CN1139400C - Medicine for treating arthritis and bone injury disease - Google Patents

Abstract

The present invention discloses a medicine for treating arthronosos and bone diseases, which belongs to the technical field of traditional Chinese medicines. The method of the medicine comprises the steps: 4.5 to 9 shares of paniculate swallowwort root, 0.5 to 1 part of natural copper, 2 to 5 shares of bungarus minimus and 0.15 to 0.6 part of naproxen are pulverized by a pulverizer after being uniformly mixed, the pulverized materials are prepared into powder after being sieved, and then the powder is put into medical capsules to prepare the medicine. The medicine has the reasonable prescription, the effect on treating arthronosos and relevant bone diseases and the advantages of short course of treatment, high treatment effect, no recurrence, etc. In addition, more than 98 % of patients can receive good clinic effect. The medicine is an ideal Chinese patent medicine for treating arthronosos and bone diseases.

Description

A kind of medicine for the treatment of arthrosis and orthopedic disease

Technical field

A kind of medicine for the treatment of arthrosis and orthopedic disease that the present invention relates to belongs to the Chinese medicine technical field.

Background technology

Rheumatic, rheumatoid arthritis, joint movement disorder diseases such as orthopedic disease such as hyperosteogeny rheumatism involving the bone, scapulohumeral periarthritis, cervical spondylosis, prolapse of lumbar intervertebral disc are a kind of common and be difficult to the disease of thoroughly curing.Motherland's medical science thinks that mostly the pathogenic factor of this class disease is the endogenous cause of ill deficiency of the liver and kindey, diseases caused by exogenous pathogenic factor wind, cold, wet, hot, thus cause qi depression to blood stasis and cause.Clinical symptoms mostly is neck, shoulder, waist, the pain that has a pain in the leg, numb all over the body, and muscle, joint, muscles and bones are ached, and are weighing joint stuffiness, joint movement disorder etc.The many employings of the traditional Chinese medical science consolidate cold expelling, dispel wind and remove dampness, declare the Therapeutic Principle of the network of promoting blood circulation.Usually adopt Chinese medicinal formulae, Chinese patent medicines such as Chinese medicine decoction, DAHUOLUO WAN, Tongbi pill, anti-hyperosteogeny pill, JINGFUKANG, YAOTONGNING.These Therapeutic Method and decoction, Chinese patent medicine usually can only be at a certain diseases, and its course of treatment is long, curative effect is very not remarkable, the not very good and easy recurrence of cure rate.

Summary of the invention

Purpose of the present invention is intended to improve above-mentioned deficiency, and a kind of evident in efficacy, short treating period is provided, and can the double medicine of controlling arthrosis and orthopedic disease.

In order to achieve the above object, the principles of formulating prescriptions of the present invention: and blood blood stasis dispelling, anti-inflammatory analgetic, wind-damp dispelling, cold expelling numbness.

Medicament composing prescription of the present invention is as follows, and in weight portion: it is by Radix Cynanchi Paniculati 4.5-9 part, Pyritum 0.5-1 part, and Agkistrodon 2-5 part, naproxen 0.15-0.6 part behind the mix homogeneously, utilizes pulverizer to pulverize, by becoming powder behind the dusting cover, the medical capsule of packing into.

The Radix Cynanchi Paniculati acrid in the mouth is warm in nature, returns liver, stomach warp.Has wind-expelling pain-stopping, the effect that dampness removing is antipruritic.The outer dispelling wind evil of its hot flavor, interior qi and blood circulation promotion and pain relieving, antipruritic.Be widely used in the various pain due to rheumatism, cold coagulation, the stagnation of QI, the blood stasis.Radix Cynanchi Paniculati contains volatile oil, contains paeonol in the oil; Corallium Japonicum Kishinouye glycoside unit, deacylcynanchogenin, flavonoid glycoside etc. in also containing; Still contain saccharide, aminoacid, micro-alkaloid etc.Radix Cynanchi Paniculati has significant analgesia role.Radix Cynanchi Paniculati can make the tension force of animal smooth muscle descend, and the strong convulsion of ileum that energy antagonism barium chloride causes is twin.The Radix Cynanchi Paniculati injection can significantly reduce the spontaneous activity of mice, makes mice peace and quiet, blepharoptosis, and certain sedation is arranged.Radix Cynanchi Paniculati also has has certain therapeutical effect to toothache and traumatic injury etc.

The Pyritum acrid in the mouth is flat, returns Liver Channel.Eliminating stasis to stop pain is arranged, the effect that synthetism is cured the wound.The capable master of loosing of Pyritum acrid in the mouth goes into the Liver Channel blood system.Eliminating stasis to stop pain can promote union of fracture, the key medicine of curing the wound for the orthopedics department synthetism.Pyritum mainly contains ferrous disulfide, also impurity such as cupric, nickel, antimony, silicon, barium, calcium, zinc, manganese.Pyritum has the union of fracture of promotion effect, still can promote skein cell and hemoglobin hypertrophy in bone marrow self and the peripheral blood.

The Agkistrodon sweet-salty is warm in nature, and is poisonous, returns Liver Channel.Has dispelling wind and removing obstruction in the collateral, the effect of pain relieving counteracting toxic substances.This moral character is apt to away scurry, in walk internal organs, outer thorough fur, nowhere less than, can search ailment said due to cold or exposure, saturating joint, arresting convulsion is taken out, relieving convulsion is jerked, treat malignant boil, except that the tinea leprosy.Key medicine for insensitive impediment paralysis, tinea leprosy malignant boil.Spend Herba potentillae kleinianae protein, fat, Saponin, Palmic acid, lauric acid in vain.Contain hyaluronidase, Defibrinogenase, lipase, anticoagulin and thrombin-like material in the snake venom of head poison gland.Agkistrodon has calmness, hypnosis, analgesic activity to mice, slow wave can occur on the electroencephalogram of rabbit, and high amplitude promptly shows inhibitory action.The Agkistrodon extract can reduce the permeability of blood capillary, and oozing out when reducing inflammation has certain antiinflammatory action, and compositions such as Palmic acid that it is contained and lauric acid may be antiphlogistic effective ingredient.Agkistrodon has the thrombin-like effect, fibrinolysis is also arranged, and can make the fibrinogen deposition in the blood plasma is fibrin, forms little clot and is deposited in the blood plasma, the little clot of these fibrins dissolves through the plasmin effect, and Fibrinogen is exhausted.

Naproxen, chemistry naproxen by name, trade name has another name called congex, is white or micro white crystalline powder, odorless.Be soluble in ethanol.This product is the non-steroidal anti-inflammatory analgesics.Antiinflammatory action is about 11 times of Phenylbutazone, and analgesic activity is about 7 times of aspirin, and refrigeration function is about 22 times of aspirin, is a kind of antiinflammatory, analgesia, antipyretic of high-efficiency low-toxicity.Be used for rheumatoid arthritis, osteoarthritis, each rheumatoid disease, tendon spondylitis, acute gout etc.To caused pain of various diseases and heating, the better antipyretic analgesic effect is arranged also.Be particularly useful for to tolerate the patient of aspirin, indometacin etc. because of anemia, gastroenteropathy or other reason.The untoward reaction of this product be accidentally feel sick, vomiting, dyspepsia, constipation, gastrointestinal hemorrhage, insomnia or drowsiness, headache, dizziness, tinnitus, pruritus, erythra, vasodilation, visual disorder and bleeding time prolongation, be generally slight and temporary transient discomfort, do not need therapy discontinued.

A kind of drug absorption for the treatment of arthrosis and orthopedic disease of the present invention the Chinese medicine chief, has reasonable recipe, can receive the double effect of controlling arthrosis and relevant orthopedic disease, there are taking convenience, low price, toxic and side effects little simultaneously, reduce the characteristics of patient economy burden, and have advantages such as short treating period, curative effect is high and do not recur.Take the 1-3 month, the patient more than 98% all can receive good clinical effectiveness.

Concrete embodiment

For understanding better and implementing, the present invention is described in detail below in conjunction with embodiment.

Embodiment 1, takes by weighing Radix Cynanchi Paniculati 45kg, Pyritum 5kg, and Agkistrodon 20kg, naproxen 1.5kg behind the mix homogeneously, utilizes pulverizer to pulverize, by becoming powder behind the dusting cover, packs in the medical capsule by the specification of 0.3g/ ball, every bottle 100 particle packing.

Embodiment 2, take by weighing Radix Cynanchi Paniculati 90kg, Pyritum 10kg, and Agkistrodon 50kg, naproxen 6kg behind the mix homogeneously, utilizes pulverizer to pulverize, by becoming powder behind the dusting cover, packs in the medical capsule by the specification of 0.3g/ ball, every bottle 100 particle packing.

Embodiment 3, take by weighing Radix Cynanchi Paniculati 60kg, Pyritum 8kg, and Agkistrodon 35kg, naproxen 4kg behind the mix homogeneously, utilizes pulverizer to pulverize, by becoming powder behind the dusting cover, packs in the medical capsule by the specification of 0.3g/ ball, every bottle 100 particle packing.

Embodiment 4, take by weighing Radix Cynanchi Paniculati 450kg, Pyritum 100kg, and Agkistrodon 35kg, naproxen 5kg behind the mix homogeneously, utilizes pulverizer to pulverize, by becoming powder behind the dusting cover, packs in the medical capsule by the specification of 0.5g/ ball, every bottle 100 particle packing.

Embodiment 5, take by weighing Radix Cynanchi Paniculati 600kg, Pyritum 100kg, and Agkistrodon 500kg, naproxen 50kg behind the mix homogeneously, utilizes pulverizer to pulverize, by becoming powder behind the dusting cover, packs in the medical capsule by the specification of 0.5g/ ball, every bottle 100 particle packing.

Embodiment 6, take by weighing Radix Cynanchi Paniculati 900kg, Pyritum 100kg, and Agkistrodon 200kg, naproxen 40kg behind the mix homogeneously, utilizes pulverizer to pulverize, by becoming powder behind the dusting cover, packs in the medical capsule by the specification of 0.5g/ ball, every bottle 100 particle packing.

Embodiment 7, take by weighing Radix Cynanchi Paniculati 750kg, Pyritum 75kg, and Agkistrodon 300kg, naproxen 40kg behind the mix homogeneously, utilizes pulverizer to pulverize, by becoming powder behind the dusting cover, packs in the medical capsule by the specification of 0.5g/ ball, every bottle 100 particle packing.

1, clinical diagnosis and criterion of cure

1.1 list of references: the Chinese medicine industry standard ZY/T001.1-001.9-94 of the People's Republic of China (PRC) " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " (publishing house of issue Nanjing University of State Administration of Traditional Chinese Medicine 1994 July the 1st edition).

" surgery " Wu Zaide chief editor (People's Health Publisher February calendar year 2001 the 5th edition).

" practical surgery handbook Li Biao Wu Jin art is write (Hunan science tech publishing house 2000 November the 1st edition)

1.2 clinical diagnosis standard and efficacy evaluation

1.2.1 rheumatic arthritis

Rheumatic arthritis waits the exopathogen invasion because wind and cold is damp and hot, impatency meridians joint, QI-blood circulation is not smooth, with the whole body joint be migration red, swell, weighing, pain is main clinical manifestation.The so-called rheumatism numbness of the traditional Chinese medical science.

Diagnosis basis.Walk to scurry pain based on the big joint of extremity, the companion is weighing, miserable, numb, joint joint stuffiness.Diseases such as aversion to cold, heating are arranged more.Before sick pharyngalgia tonsillitis history is arranged more, or paddle and drench with rain, occupy for a long time the wetland history.Part patient can have low grade fever, extremity erythema iris, or erythema nodosum.But normal heart is got involved.Erythrocyte sedimentation rate speeds, and antistreptolysin " O " is greater than 500 units.

Syndrome-classification.Migratory arthralgia (ailment said due to cold or exposure wins partially): the limbs joint myalgia, migration is indefinite, joint stuffiness, or see fever with aversion to wind etc.Thin white fur of tongue, floating pulse.

Arthralgia aggravated by cold (cold-evil wins partially): limbs joint pain is acute, meets cold increasing the weight of, pain alleviated while getting warmth, and light night in daytime is heavy, and the joint can not be bent and stretched, and sore spot is not red, and that touches is not hot.White, slippery and moist fur, stringy and tense pulse.

Damp arthralgia (damp wins partially): limbs joint is weighing aches, and sore spot is fixed, and lower limb are for very, or swelling is arranged, numbness of the skin, and the weather wet weather increases the weight of.White and greasy fur, relaxed and soft pulse.

Pyretic arthralgia (pathogenic heat wins partially): onset is hurried, arthralgia, and local red and swollen scorching hot, pain can not be touched, and joint stuffiness gets cold easypro slightly.Fever and aversion to wind is arranged, hyperhidrosis, restlessness and thirst more.Red tongue with yellow fur, slippery and rapid pulse.

Paralysis (QI and blood deficiency): with the passing of time the course of disease does not heal repeatedly, arthralgia, the time heavy when light.Yellowish complexion is simple and unadorned, and the cardiopalmus spontaneous perspiration is dizzy weak.Pale tongue, tongue are thin in vain, soft pulse.

Efficacy evaluation.Cure: transference cure, joint motion is normal, and lab testing is normal.Take a turn for the better: symptom is clearly better, and lab testing has improvement.Do not heal: symptom and lab testing do not have progress.

1.2.2 rheumatoid arthritis

Rheumatoid arthritis be by the wind-cold damp pathogen visitor in the joint, QI and blood numbness resistance causes with little arthralgia, swelling, morning, deadlock was the disease of characteristics.

Diagnosis basis.Originally how to be the symmetry pain and swelling with little joint, to be mainly in articulations digitorum manus or back, morning, deadlock was movable unfavorable.Onset is slow, repeatedly protracted course of disease, emaciated physique gradually.Chang Yin is affected by the cold damp and shows effect repeatedly.The disease joint of getting involved for a long time is fusiformis swelling, tenderness tenderness, pain when movable.The later stage joint deformity is stiff, smooth surface, amyotrophy on every side.The minority case has subcutaneous nodule.Blood is looked into the rheumatoid factor positive, stage of attack erythrocyte sedimentation rate can speed.The X line is taken the photograph the visible osteoporosis of sheet and is changed, or the joint surface of bone corrodes and be subluxation or dislocation, and sclerotin is tetanic, articular surface fusion etc.

Syndrome-classification.Wind-cold-damp retention: joint swelling and pain, localized pain, morning, stiff joint stuffiness was met the play of cold then pain, and local fear of cold is afraid of cold.Thin white fur of tongue, floating and tense pulse or heavy tight.

The rheumatism heat stagnation: joint congestion and swelling pain is as burning, morning deadlock, limitation of activity.Have fever with aversion to wind concurrently, have antiperspirant not understand, restlessness and thirst is convenient to dark coloured urine.Red tongue, yellow fur or dry, slippery and rapid pulse.

Phlegm and blood stasis: the joint overflows that swollen with the passing of time stiffness and deforming bends and stretches limitedly, and pain is fixed, pain as being stabbed, and light night in daytime is heavy, and xerostomia is the desire drink not.Purplish tongue, tongue are greasy in vain or yellow greasy, thready and hesitant pulse or fine and smooth.

The cold coagulation of suffering from a deficiency of the kidney: arthralgia swelling, morning deadlock, movable unfavorable, fear of cold is afraid of cold, refreshing tired lazyness is moving, aching pain in waist and back, pitching is unfavorable, cold weather increases the weight of.White, slippery and moist fur, deep-thready pulse.

The hepatic and renal YIN deficiency: sick arthroncus deformity for a long time, the scorching hot pain in local joint, joint stuffiness, the thin bone of shape is upright, soreness of the waist and knees.With dizziness and tinnitus, night sweat, insomnia.Red tongue, few tongue, thready and rapid pulse.

Deficiency of qi and blood: arthralgia, swelling is stiff, apathy, it is difficult to take action, pale white complexion, cardiopalmus spontaneous perspiration, spiritlessness and weakness.Light red tongue, white and thin fur, thready and weak pulse.

Efficacy evaluation.Cure: arthralgia, swelling disappear, and movable function is normal, and lab testing is normal.Take a turn for the better: arthralgia, swelling alleviate, and movable function takes a turn for the better, and lab testing has improvement.Do not heal: arthralgia, swelling and lab testing no change.

1.2.3 scapulohumeral periarthritis

Diagnosis basis.Chronic strain, wound muscles and bones, insufficiency of vital energy and blood is affected by the cold due to the damp again.Send out the age about 50 years old well, women's sickness rate is higher than the male, and right shoulder is more common in physical labourer more than left side shoulder, mostly is chronic disease.Shoulder perimembranous pain, with night for very, often bring out shoulder joint movement function obstacle because of Changes in weather and fatigue.The shoulder muscle atrophy, takeing on forward and backward, the outside all has tenderness, and the abduction function limitation is obvious, typical " shouldering shoulder " phenomenon occurs.It is negative that the X ray examination mostly is, the visible osteoporosis of course of disease person of a specified duration.

Syndrome-classification.The wind and cold wet type: shoulder string pain, meet wind and cold and increase bitterly, it is slow to get warm pain, the anemophobia aversion to cold, or shoulder has sense of heaviness.Pale tongue, white and thin fur or greasy, stringy and rolling pulse or stringy and tense pulse.

Stasis type: shoulder swelling, pain with tenderness, with night for very.Dark tongue quality or ecchymosis is arranged, Tai Bai or BOHUANG, stringy pulse or carefully puckery.

The asthenia of qi and blood type: shoulder is ached, and tired back pain increases the weight of, and the companion has a dizzy spell, the lazy speech of breathing hard, palpitation and insomnia, limbs fatigue.Pale tongue, tongue is few or white, thready and weak pulse or heavy.

Efficacy evaluation.Cure: shoulder pain disappears, and shoulder joint function recovers fully or substantially.Take a turn for the better: shoulder pain alleviates, and movable function improves.Do not heal: symptom does not have improvement.

1.2.4 cervical spondylosis

Diagnosis basis.Chronic strain or trauma history are arranged.Or there are cervical vertebra congenital malformation, cervical vertebra to move back the change of shape sexually transmitted disease (STD).Be mainly in middle age more than 40 years old, the worker or get used to seeing for a long time TV, video recording person of bowing for a long time often is chronic disease.Neck, shoulder and back ache, headache and dizzy, neck board is hard, upper limb numbness.The cervical region movable function is limited, and going up the angle in pathological changes cervical spine, the Ipsilateral scapula often has tenderness, can touch strip scleroma, can have the upper limb muscular strength to weaken and amyotrophy, the brachial plexus distraction test positive.The pressure head test is positive.X line normotopia is taken the photograph sheet and is shown, the uncovertebral joint hypertrophy, and mouth-open can have the cutter shape prominent askew partially, and the side position is taken the photograph sheet and is shown that cervical curvature becomes straight, and narrowing of intervertebral space has hyperosteogeny or ligament calcification, and loxosis is taken the photograph the visible intervertebral foramina of sheet and is diminished.CT and magnetic resonance examination are meaningful to qualitative level diagnosis.

Syndrome-classification.Tcm syndrome classification: wind and cold wet type: neck, shoulder, upper limb string pain numbness, based on pain, head has sense of heaviness, and Wry Neck is movable unfavorable, the aversion to cold anemophobia.Light red tongue, white and thin fur, stringy and tense pulse.

Qi depression to blood stasis: neck and shoulder part, upper limb twinge, sore spot is fixed, with numb limbs and tense tendons.Dark tongue quality, stringy pulse.

Phlegm-damp resistance network: have a dizzy spell, heaviness of the head as if it were tightly bandaged, numb limbs and tense tendons is meciless, and is indigestion and loss of appetite.Tongue is dark red, thick and greasy fur, stringy and rolling pulse.

Deficiency of the liver and kindey: dizziness and headache, Hiccough and deaf, insomnia and dreamful sleep, numb limbs and tense tendons, flushed face with red ears.Red tongue with a little fluid, stringy pulse.

Deficiency of qi and blood: have a dizzy spell pale complexion, shortness of breath and palpitation, numb limbs and tense tendons, fatigue and weakness.The light red tongue tongue is few, thready and weak pulse.

Pathological classification.The neck type: pillow cervical region pain, the neck limitation of activity, cervical muscle is stiff, and corresponding pressure pain point is arranged.X-ray film shows: the cervical vertebrae physiological radian changes in lesion segment.

Spondylotic radiculopathy: cervicodynia companion upper limb radiating pain, increase the weight of when stretching behind the neck, pressurized nerve root skin sections areal area decreased sensation, tendon reflex is unusual, amyotrophy, muscular strength goes down, neck limitation of activity, distraction test, the pressure head test positive.Cervical vertebra X line shows: hyperosteogeny, and the uncovertebral joint hypertrophy is obvious, narrowing of intervertebral space, intervertebral foramina diminishes.Vegetation and nerve root canal narrow down behind the visible vertebral body of CT.

Myeloid form: early stage lower limb are felt nervous, and walking is unstable, as carrying out the sandy beach, late period one side lower limb or quadriplegia, incontinence of urination and defecation or urine retention.The following sensory disturbance of pressurized segments of spinal cord, muscular hypertonia, hyperreflexia, fibrae pyramidales is levied the positive.X-ray film shows: stenosis of disc space, vertebral body trailing edge hypertrophy are serious and charge into canalis spinalis.CT, MRI check and show: canalis spinalis narrows down, vertebral body trailing edge proliferation or annuler bulge compressing spinal cord.

Vertebral artery type: headache, dizzy, tinnitus, deafness, blurring of vision has position to damping off, when bend the cervical vertebra rear flank, sx.The X sheet shows: transverse process pitch smaller, uncovertebral joint hypertrophy.CT examination can show that left and right sides transverse foramen size is asymmetric, and a side is narrow relatively.Vertebral arteriography sees that vertebral artery is tortuous, attenuates or blocks fully.

Adrenergic type: eyelid is unable, blurred vision, and platycoria, the eye socket distending pain is shed tears, headache, migraine, dizziness, the pillow cervicodynia, tachycardia or bradycardia, precordial pain, blood pressure increases, and extremity are cool or point rubescent heating, a side hyperhidrosis or hypohidrosis etc.X-ray film is seen hook vertebra hypertrophy, and the intervertebral foramina stenosis is narrow, and the cervical vertebrae physiological radian changes or dislocation in various degree arranged.Vertebral arteriography has the pressurized phenomenon.

Efficacy evaluation.Cure: original various disease disappears, and muscular strength is normal, and neck, limb functional recover are normal, can participate in and normally work or work.Take a turn for the better: original various disease alleviates, and neck, shoulder and back ache alleviate, and neck, limb function improve.Do not heal: symptom does not have improvement.

1.2.5 prolapse of lumbar intervertebral disc

Diagnosis basis.Waist wound, chronic strain or the thermal history of catching cold are arranged.Most of patient has the chronic back pain history at premorbid.Often betide person between twenty and fifty.Lumbago is to buttocks and lower limb radiation, and pain increased the weight of when abdominal pressure increased (as cough, sneeze).Scoliosis, the waist physiologic radian disappears, and the diseased region vertebra is other tenderness, and to lower limb radiation, waist limitation of activity.The lower limb innervation district that gets involved feels irritatedly or blunt, and amyotrophy can appear in course of disease elder.Straight lower limb is raised or is strengthened the test positive, and knee joint, Achilles tendon reflex weaken or disappear, and the big toe back of the body power of stretching weakens.The X line is taken the photograph the sheet inspection: scoliosis, and waist physiology lordosis disappears, and the pathological interspinal dish may narrow down, and neighboring edge has osteophytosis.CT examination can show the position and the degree of intervertebral disk hernia.

Syndrome-classification.Tcm syndrome classification: syndrome of blood stasis: lumbago and skelalgia is as thorn, localized pain, and a day light night is heavy, and the waist plate is hard, and the pitching rotation is limited, the sore spot tenderness.Body of the tongue is dark violet, or ecchymosis is arranged, stringy and tense pulse or puckery.

Cold-damp syndrome: waist lower limb cold type of pain is weighing, and it is unfavorable to change one's position, and the pain that reposes does not subtract, and catches cold and wet weather increases the weight of, and limbs are sent out cold.Pale tongue, Tai Bai or greasy, deep and tense pulse or moisten slow.

Damp-heat syndrome: flank pain, lower limb is soft unable, and sore spot is with hotness, and chance heat or rainy day increase bitterly, movable back alleviation of pain, aversion to heat is thirsty, oliguria with reddish urine.Yellow and greasy fur, soft and rapid pulse or stringy and rapid pulse.

Caused by liver and kidney deficiency: soreness of waist pain, the lower limb knee joint is weak, and fatigue is more very, and is for sleeping in then alleviate.Inclined to one side yang deficiency person, hands and feet being not warm, deficiency of QI with disinclination to talk waist lower limb is sent out cold, or sexual impotence, premature ejaculation are arranged, and women's leukorrhagia is rare clearly, pale tongue, deep-thready pulse.Deficiency of YIN person partially, dry throat and mouth, flushed face, fatigue and weakness, vexed insomnia, dreaminess or seminal emission is arranged, women's leucorrhea with yellow discharge flavor is smelly, the few tongue of red tongue, stringy,thready and rapid pulse.

Pathology typing: one-sided intervertebral disk hernia: low back pain is accompanied a side lower limb radiating pain, and scoliosis, waist physiology lordosis reduce or disappear, and the other tenderness of pathological interspinal dish Ipsilateral vertebra can be radiated the straight-leg raising test positive along sciatic nerve to lower limb.CT examination: intervertebral disc is side-prominent to canalis spinalis one.

The bilateral intervertebral disk hernia: low back pain, companion's bilateral lower limb radiating pain, waist physiology lordosis reduces or disappears, and pathological interspinal dish both sides vertebra is other all tenderness, can radiate two lower limb straight-leg raising test positives along sciatic nerve to lower limb.CT examination: intervertebral disc is outstanding to the left and right, and as seen free piece.

Last mo(u)ld bottom half intervertebral disk hernia: most of patient only has the lumbago symptom, the visible Schmorl tuberosity of X-ray examination pathological interspinal dish.

Central type intervertebral disk hernia: except that the symptom that lumbago and skelalgia occurs, cauda equina nerve stress disorders such as perineal position numbness and fecal and urinary functions obstacle also can occur.CT examination: intervertebral disc is outstanding to the center direction.

Efficacy evaluation.Cure: lumbago and skelalgia disappears, and straight lower limb is raised more than 70 °, can recover former work.Take a turn for the better: lumbago and skelalgia alleviates, and the waist movable function improves.Do not heal: symptom, sign do not have improvement.

1.2.6 rheumatism involving the bone

Rheumatism involving the bone is because worn with age, and bone loses and nourishes, disorder of QI and blood, due to part or whole body osteoarthrosis degenerate and change.Clinical manifestation is with big arthralgia, and limitation of activity is a primary symptom.Be more common in degenerative osteoarthritis, hypertrophy sexually revises.Doctor trained in Western medicine is referred to as hyperosteogeny, osteoarthritis, degenerative osteoarthritis etc.

Diagnosis basis.From the beginning of seeing that waist lower limb, spinal column, knee joint etc. have a dull ache more, bend and stretch, pitching, change one's position unfavorablely, light activity is alleviated slightly, and climate change increases the weight of, and does not touchingly repeatedly heal.Insidious onset, morbidity slowly is more common in person in middle and old age.But local joint mild swelling, often there are noise made in coughing or vomiting thorn sound or grating in the joint when movable.The visible amyotrophy of severe patient, joint deformity, the curved back of the body camel of waist.The X line is taken the photograph the sheet inspection: show osteoporosis, articular surface is irregular, and the joint space is narrow, the sclerosis of subchondral bone matter, and edge lip sample changes hyperosteogeny formation.Heavy, anti-" O ", mucin, the rheumatoid factor etc. of having a blood test are differentiated mutually with rheumatic, rheumatoid arthritis.

Syndrome-classification.The marrow of suffering from a deficiency of the kidney loses: the joint has a dull ache, soreness of the waist and knees, and the waist lower limb is unfavorable, and pitching is changed one's position unfavorable.With dizziness, tinnitus, deafness, dizzy.Light red tongue, white and thin fur, thready pulse.

The yang deficiency cold coagulation: limbs joint pain, heavily outstanding, joint stuffiness, Changes in weather increases the weight of, and light night in daytime, heavily pain increase in intensity under coldness must hotly subtract slightly.Light red tongue, tongue is white, and deep pulse blood is slow.

Stagnation of blood stasis: joint sting, sore spot is fixed, and joint deformity is movable unfavorable, or the curved back of the body camel of waist, dim complexion, deep pulse or carefully puckery.

Efficacy evaluation.Cure: arthralgia, swelling disappear, and it is normal that movable function recovers, and lab testing is normal.Take a turn for the better: arthroncus, pain relief, movable function takes a turn for the better.Do not heal: arthralgia, swelling no change.

2, clinical data.Treated arthrosis and orthopedic disease 267 examples from 2000 altogether to calendar year 2001.

Name of disease	The example number	Cure routine number	Routine number takes a turn for the better	Cure rate (%)	Total effective rate (%)
						Rheumatism involving the bone	67	59	7	88	98.5
Intervertebral disc prolapse	48	40	7	83.3	98
						Scapulohumeral periarthritis	46	42	4	91.3	100
Cervical spondylosis	59	55	3	93.2	98
						Rheumatic arthritis	26	23	2	88.5	96
Rheumatoid arthritis	21	18	2	85.7	95
						Add up to	267	237	25	88.8	98.2

3, administrated method.Day 2 times, each 1.2-1.5 gram, one after each meal, 50 days is a course of treatment.

4, through to the discussion of technique scheme as can be seen, the mutual compatibility of various medicines that prescription adopted in the technical program is consistent with the principles of formulating prescriptions with blood blood stasis dispelling, anti-inflammatory analgetic, wind-damp dispelling, cold expelling numbness.

5, model case

Example 1, Zhang Lihua, woman, 65 years old, Zang Jia village village, Zang Jiazhuan town, Xixia City, Shandong Province.Be diagnosed as prolapse of lumbar intervertebral disc (L through the People's Hospital, Xixia City in April, 1999 _3,4, L _4,5), treatment is had no result through how tame hospital and clinic, in March calendar year 2001 here seek medical advice, by every day 2 times, each 1.2 overcome usefulness, pain can walk with onlying after taking medicine 20 days, continues to obey and fully recovers in 30 days, follows up a case by regular visits to so far and recurs.

Example 2, Li Fuhai, man, 58 years old, Luo Jia village, Liu Jiahe township, Xixia City, Shandong Province.Be diagnosed as right kneecap matter hypertrophy through the X of the People's Hospital, Xixia City radiodiagnosis x in November, 2000, cooperates physical therapy through the clothes anti-hyperosteogeny pill, fail to respond to any medical treatment the back in July calendar year 2001 here seek medical advice, by every day 2 times, each 1.2 overcome usefulness, through the recovery from illness half course of treatment (25 days) of taking medicine, not recurrence so far.

Example 3, Mu Fengzhang, woman, 50 years old, Bei Bo village, Xixia City Guan Li town.Be diagnosed as prolapse of lumbar intervertebral disc (L through Laiyang City PLA 145 hospital's CT examination in July, 1998 _4,5) 0.3cm, not good through therapeutic effect, in October calendar year 2001 here seek medical advice, by every day 2 times, each 1.2 overcome usefulness, recovery from illness after taking medicine 50 days.

Example 4, Li Shue, woman, 56 years old, the Dong Jia village, Liu Jiahe township, Xixia City, Shandong Province.Be diagnosed as scapulohumeral periarthritis (right side) in August, 2000 through the People's Hospital, Xixia City, invalid through taking Drug therapys such as SHENJIN DAN, in August calendar year 2001 here seek medical advice, by every day 2 times, each 1.2 overcome usefulness, and pain is ended after taking medicine 12 days, activity can, continue clothes recovery from illness after 20 days, do not follow up a case by regular visits to recurrence.

Example 5, Jiang Cuimei, woman, 50 years old, the Huang Jia village, Xixia City Liu Jiahe township.Be diagnosed as scapulohumeral periarthritis through the People's Hospital, Xixia City February calendar year 2001, not good through therapeutic effect, in July calendar year 2001 here seek medical advice, by every day 2 times, each 1.5 overcome usefulness, recovery from illness after taking medicine 25 days.

Example 6, Lin Guofang, woman, 48 years old, the Bei Linjia village, villa garden district, Xixia City, Shandong Province.Be diagnosed as hyperosteogeny of cervical vertebra through the People's Hospital, Xixia City February calendar year 2001, through failing to respond to any medical treatment, in July calendar year 2001 here seek medical advice, by every day 2 times, each 1.5 overcome usefulness, 5 days sxs after taking medicine, recovery from illness after 25 days.

Example 7, Ma Defu, man, 68 years old, Ma Jiatuan village, villa garden, Xixia City district.Be diagnosed as right kneecap matter hypertrophy in July, 2000 through the People's Hospital, Xixia City, fail to respond to any medical treatment after taking medicines such as anti-hyperosteogeny pill, in August calendar year 2001 here seek medical advice, by every day 2 times, each 1.5 overcome usefulness, and not recurrence is followed up a case by regular visits to so far in the half recovery from illness course of treatment after taking medicine.

Example 8, Sheng Ruiping, man, 46 years old, village behind the palace, district, villa garden, Xixia City.Be diagnosed as cervical spondylosis through the People's Hospital, Xixia City in March, 2000, after failing to respond to any medical treatment in March calendar year 2001 here go to a doctor, by every day 2 times, each 1.5 overcome usefulness, 10 days take effect after taking medicine, continue clothes recovery from illness after 30 days, follow up a case by regular visits to so far recurrence.

Example 9, Mu Yanhua, woman, 69 years old, Mu Jia village village, Xixia City Liu Jiahe township.Be diagnosed as rheumatoid arthritis through the People's Hospital, Xixia City in 1999, through how tame hospital and clinic's treatment, poor effect, in March calendar year 2001 here see a doctor, by every day 2 times, each 1.5 overcome usefulness, take behind the medicine and to take effect in 10 days, be almost recovered after 40 days, can participate in normally and work continue clothes.

Example 10, Mu Baodi, man, 68 years old, Laishan District, Yantai City.The semi-annular jade pendant top hospital diagnosis of giving birth through the Yantai City in 1998 is a rheumatoid arthritis, the effect of seeking medical advice through many places is not good enough, in in November, 2000 here see a doctor, by every day 2 times, each 1.5 overcome usefulness, the obvious effect of 20 daybreaks after taking medicine, continue and obeyed 80 days, symptom is removed, and life can be taken care of oneself, and can participate in certain physical work, follow up a case by regular visits to respond well so far.

Example 11, the refined mountain of clothing, man, 41 years old, the little distant Ge Zhuan of Shandong Province's Laiyang City village was diagnosed as rheumatic arthritis through Laiyang City central hospital in 1997, not good enough through the many places hospital effect of seeking medical advice, in in March, 2000 here see a doctor, by every day 2 times, each 1.5 overcome usefulness, the sky takes effect surplus in the of 10 after taking medicine, continue and obeyed 30 days, recurrence is followed up a case by regular visits to so far in recovery from illness.

Example 12, Wang Zhibin, man, 54 years old, Yantai City's Zhifu District.The semi-annular jade pendant of giving birth through the Yantai City in April, 1998 top hospital is diagnosed as rheumatic arthritis, and therapeutic effect is not good enough through many places, in April, 2000 here seek medical advice, by every day 2 times, each 1.5 overcome usefulness, fully recover in a day back through taking medicine surplus in the of 30.

Claims (1)

1, a kind of medicine for the treatment of arthrosis and orthopedic disease, in weight portion, it is by Radix Cynanchi Paniculati 4.5-9 part, Pyritum 0.5-1 part, Agkistrodon 2-5 part, naproxen 0.15-0.6 part is behind the mix homogeneously, utilize pulverizer to pulverize, by becoming powder behind the dusting cover, the medical capsule of packing into.