CN113881552A

CN113881552A - Cell crusher

Info

Publication number: CN113881552A
Application number: CN202111198373.0A
Authority: CN
Inventors: 罗磊; 王梓光; 罗梓成
Original assignee: Bozhou Qiananzhi Medical Biotechnology Co ltd
Current assignee: Bozhou Qiananzhi Medical Biotechnology Co ltd
Priority date: 2021-10-14
Filing date: 2021-10-14
Publication date: 2022-01-04

Abstract

The invention provides a cell crusher, which comprises a base, wherein a rotating rod and a first servo motor used for rotating the rotating rod are arranged on the base, a plurality of connecting rods distributed in the circumferential direction are arranged on the rotating rod, a placing block is arranged at one end, away from the rotating rod, of each connecting rod, a placing groove is formed in each placing block, two fixing plates are arranged on each placing block, each placing groove is located between the two fixing plates, a positioning frame located above each placing groove and a driving piece used for driving each positioning frame to move in the vertical direction of the corresponding fixing plate are arranged on the opposite sides of the two fixing plates, and a cell crushing mechanism used for crushing cells is arranged on the base. The invention provides a cell crusher, which can be used for conveniently and rapidly feeding and discharging liquid in a container and can also effectively prevent the phenomenon of shaking during crushing.

Description

Cell crusher

Technical Field

The invention relates to the technical field of cell crushing, in particular to a cell crusher.

Background

The ultrasonic cell crusher is a multifunctional and multipurpose instrument which utilizes strong ultrasound to generate cavitation effect in liquid and carry out ultrasonic treatment on substances, can be used for crushing animal and plant tissues, cells, bacteria and spore strains, and can be used for emulsifying, separating, dispersing, homogenizing, extracting, degassing, cleaning, accelerating chemical reaction and the like; the machine is widely applied to teaching, scientific research and production in the fields of biochemistry, microbiology, medicinal chemistry, surface chemistry, physics, zoology, agriculture, medicine, pharmacy and the like.

The existing cell crusher has certain disadvantages when in use, is inconvenient for carrying out quick feeding and discharging on a container filled with liquid, and is easy to cause the cell crusher to shake and be inconvenient for fixing the cell crusher when the liquid in the container is crushed.

Disclosure of Invention

Based on the technical problems in the background art, the invention provides a cell crusher

The invention provides a cell crusher, which comprises a base, wherein a rotating rod and a first servo motor used for rotating the rotating rod are installed on the base, a plurality of connecting rods distributed in the circumferential direction are installed on the rotating rod, a placing block is installed at one end, away from the rotating rod, of each connecting rod, a placing groove is formed in each placing block, two fixing plates are installed on each placing block, the placing grooves are located between the two fixing plates, a positioning frame located above the placing grooves and a driving piece used for driving the positioning frames to move in the vertical direction of the fixing plates are installed on the opposite sides of the two fixing plates, and a cell crushing mechanism used for crushing cells is installed on the base.

Preferably, the fixed plate is L type structure, place the piece in and seted up the rotation chamber, the driving piece includes gear, threaded rod, rack, sleeve, gear revolve connects and rotates the intracavity, the vertical connection of threaded rod is on the gear and the threaded rod one end of keeping away from the gear rotates and passes and place the piece and rotate with the fixed plate and be connected, place the piece in set up with rack looks adaptation and with the chamber of inserting that rotates the chamber intercommunication, rack slides and passes and insert chamber and rack and install a plurality of racks with gear engaged with, set up the spout of vertical setting on the fixed plate, sleeve thread cover establishes on the threaded rod and install on the sleeve with spout sliding connection's stopper, the locating rack is installed on the sleeve.

Preferably, the locating rack is including installing the dead lever on the sleeve and transversely setting up, it keeps away from telescopic one end and is connected with the telescopic link that inserts smooth intracavity to have smooth chamber and dead lever in the dead lever, threaded connection has the bolt that compresses tightly with the telescopic link on the dead lever, the fixture block of U type structure is installed to one side that the telescopic link is close to the piece of placing, install the cotton piece of two relative settings in the fixture block.

Preferably, an elastic positioning piece for locking the container is arranged in the placing groove.

Preferably, the elastic positioning piece comprises a plurality of springs and a plurality of rubber blocks, the springs are all arranged in the placing groove and distributed in an annular mode, and the rubber blocks are arranged on the springs respectively.

Preferably, cell crushing mechanism includes electronic slide rail, installation pole, transducer, amplitude transformer pole, second servo motor, carousel, electronic slide rail is vertical to be installed on the base, and the installation pole is transversely installed on the slider of electronic slide rail, and the transducer is installed in the one end that electronic slide rail was kept away from to the installation pole, and amplitude transformer installs the one side that is close to the base at the transducer, the carousel is installed and is connected with the base rotation at the one end that electronic slide rail is close to the base and carousel, it installs in first installation cavity and second servo motor to have seted up in the base, second servo motor's output is connected with the carousel, the transducer passes through the wire and connects supersonic generator.

Preferably, a cleaning mechanism for cleaning the horn is mounted on the base.

Preferably, clean mechanism includes the wash bowl, install the assembly jig on the base, install two connecting blocks on the assembly jig and be used for driving the electric putter of the vertical removal of two connecting blocks, the wash bowl sets up between two connecting blocks and rotates with two connecting blocks to be connected, it washs the chamber to have seted up in the wash bowl, wash the intracavity and install the filter screen section of thick bamboo of vertical setting and be used for driving filter screen section of thick bamboo pivoted third servo motor, the brush hair is installed to the peripheral round in the filter screen section of thick bamboo, install the drain pipe that communicates with washing chamber on the filter screen section of thick bamboo.

Preferably, the cleaning cavity is rotatably connected with a threaded disc, the filter screen cylinder is sleeved on the threaded disc in a threaded manner, a second mounting cavity is formed in the cleaning cylinder, and the third servo motor is mounted in the second mounting cavity and the output end of the third servo motor is connected with the threaded disc.

Preferably, the base is of a cross structure, a third installation cavity is formed in the base, the first servo motor is installed in the third installation cavity, and the output end of the first servo motor is connected with the rotating rod.

The cell crusher provided by the invention has the following beneficial effects:

through the design of the placing blocks and the positioning frame, as the placing blocks are arranged in a plurality of numbers and are arranged around the circumferential direction of the rotating rod, a plurality of containers filled with liquid can be placed in the placing grooves formed in the placing blocks, then the positioning frame can be driven by the driving piece to slide on the fixing plate, so that the positioning frame is tightly pressed on the edges of the containers, the positions of the containers on the placing blocks are fixed, then the rotating rod is driven by the first servo motor to drive the containers on the placing blocks to rotate, the containers filled with the liquid are placed at the lower positions of the cell crushing mechanism, the liquid in the containers can be crushed by the cell crushing mechanism, after the liquid in the container on one of the placing blocks is crushed, the rotating rod can be driven by the first servo motor again to drive the placing blocks to rotate, so that the liquid in the container which is not crushed is rotated to the lower positions of the cell crushing mechanism, and the structure can realize the rapidness of the containers filled with the liquid, the fixing device can be fixed conveniently, the shaking is prevented, and the use by people is facilitated.

Drawings

FIG. 1 is a schematic view of the overall structure of a cell crusher according to the present invention.

FIG. 2 is a schematic view of a partial plan structure of a cell crusher according to the present invention.

FIG. 3 is a schematic view of an installation structure of a plurality of placing blocks and rotating rods in the cell crusher according to the present invention.

FIG. 4 is a schematic structural diagram of a placing block in the cell crusher according to the present invention.

FIG. 5 is a schematic plan view of a placing block of the cell crusher according to the present invention.

FIG. 6 is a schematic structural diagram of a cleaning mechanism in the cell crusher according to the present invention.

FIG. 7 is an enlarged view of A in FIG. 4 according to the present invention.

Detailed Description

Referring to fig. 1-7, the present invention provides a cell crusher, which includes a base 1, wherein a rotating rod 2 and a first servo motor 3 for rotating the rotating rod 2 are installed on the base 1; the base 1 is of a cross structure, a third installation cavity is formed in the base 1, the first servo motor 3 is installed in the third installation cavity, and the output end of the first servo motor 3 is connected with the rotating rod 2; install connecting rod 4 and connecting rod 4 that a plurality of circumference distribute on the bull stick 2 and keep away from the one end of bull stick 2 and install and place piece 5, place and seted up the standing groove in the piece 5, place and install two fixed plates 6 and standing groove on the piece 5 and be located between two fixed plates 6, the locating rack 7 that is located the standing groove top position and be used for driving the driving piece that locating rack 7 removed in the vertical direction of fixed plate 6 are all installed to 6 relative one sides of two fixed plates.

In this embodiment, fixed plate 6 is L type structure, place and to have seted up the rotation chamber in 5, the driving piece includes gear 9, threaded rod 10, rack 11, sleeve 12, gear 9 rotates to be connected at rotating the intracavity, the vertical connection of threaded rod 10 is on gear 9 and threaded rod 10 keeps away from the one end rotation of gear 9 and passes and place 5 and rotate with fixed plate 6 and be connected, place and set up in 5 with rack 11 looks adaptation and with the chamber of inserting that rotates the chamber intercommunication, rack 11 slides and passes and install a plurality of racks with gear 9 looks meshing on inserting chamber and rack 11, set up the spout of vertical setting on the fixed plate 6, sleeve 12 thread bush is established on threaded rod 10 and sleeve 12 on install with spout sliding connection's stopper 13, locating rack 7 is installed on sleeve 12.

The positioning frame 7 comprises a fixing rod 71 which is installed on the sleeve 12 and transversely arranged, a sliding cavity is formed in the fixing rod 71, one end, far away from the sleeve 12, of the fixing rod 71 is connected with an expansion rod 72 inserted into the sliding cavity, a bolt 73 tightly pressed with the expansion rod 72 is connected onto the fixing rod 71 in a threaded mode, a clamping block 74 of a U-shaped structure is installed on one side, close to the placing block 5, of the expansion rod 72, and two cotton blocks 75 which are oppositely arranged are installed in the clamping block 74.

In order to fix the container conveniently, through the design of the positioning frame 7 and the driving member, the container to be fixed can be placed in a placing groove formed in the placing block 5, then the position of the telescopic rod 72 on the fixing rod 71 is adjusted, so that the fixture block 74 on the telescopic rod 72 is aligned with the edge of the container, the position of the telescopic rod 72 on the fixing rod 71 can be fixed through the bolt 73, then the rack 11 on the placing block 5 is pulled and pulled, the gear 9 is driven to rotate in the rotating cavity through the rack 11, the threaded rod 10 is driven to rotate while the gear 9 rotates, the sleeve 12 moves on the threaded rod 10, the limiting block 13 on the sleeve 12 slides in the sliding groove formed in the fixing plate 6, so that the fixture block 74 on the telescopic rod 72 gradually approaches the container, the fixture block 74 is clamped at the edge position of the container, the clamping degree can be improved through the cotton block 75 in the fixture block 74, and the structure is convenient for fixing the container, the body is prevented from greatly shaking when the liquid in the container is broken, and the stability of the container is ensured.

In this embodiment, an elastic positioning member for locking the container is provided in the placement groove. Elastic positioning element includes a plurality of springs 14, a plurality of block rubber 15, and a plurality of springs 14 are all installed in the standing groove and are the annular and distribute, and a plurality of block rubber 15 are installed respectively on a plurality of springs 14.

In order to further prevent the container from shaking, through the design of the elastic positioning piece, when the container is placed in the placing groove formed in the placing block 5, the container is abutted against the rubber blocks 15, and meanwhile, the spring 14 is extruded and generates reaction force, so that the container is clamped among the plurality of rubber blocks 15.

In this embodiment, the cell pulverization mechanism 8 for pulverizing cells is attached to the base 1. Cell crushing mechanism 8 includes electronic slide rail 81, installation pole 82, transducer 83, change width of cloth pole 84, second servo motor 85, carousel 86, electronic slide rail 81 is vertical to be installed on base 1, installation pole 82 transversely installs on the slider of electronic slide rail 81, transducer 83 installs the one end of keeping away from electronic slide rail 81 at installation pole 82, change width of cloth pole 84 installs the one side that is close to base 1 at transducer 83, carousel 86 installs the one end and carousel 86 rotation that are close to base 1 at electronic slide rail 81 and are connected, it installs in first installation cavity to have seted up first installation cavity and second servo motor 85 in base 1, the output of second servo motor 85 is connected with carousel 86, transducer 83 passes through wire connection supersonic generator.

In order to facilitate the liquid in the container to be crushed and rapidly loaded and unloaded, through the design of the rotating rod 2 and the cell crushing mechanism 8, after the container is fixed, the rotating rod 2 is driven by the first servo motor 3 to drive the container on the placing blocks 5 to rotate, so that the container filled with the liquid is placed below the amplitude transformer 84, then the amplitude transformer 84 on the transducer 83 is driven by the sliding block on the electric sliding rail 81 to approach the container, so that the amplitude transformer 84 is inserted into the liquid in the container, the liquid in the container can be crushed, after the liquid in the container on one of the placing blocks 5 is crushed, the rotating rod 2 is driven again by the first servo motor 3 to drive the placing blocks 5 to rotate, so that the liquid in the uncrushed container is rotated to the position below the cell crushing mechanism 8 to crush the liquid, and the loading and unloading structure can realize the rapid loading and unloading of the container filled with the liquid, the efficiency of work is improved.

In a further embodiment, a cleaning mechanism 16 for cleaning the horn 84 is mounted on the base 1. Cleaning mechanism 16 includes wash bowl 161, install assembly jig 17 on the base 1, install two connecting blocks 18 and be used for driving the electric putter 19 of the vertical removal of two connecting blocks 18 on the assembly jig 17, wash bowl 161 sets up between two connecting blocks 18 and rotates with two connecting blocks 18 and be connected, it washs the chamber to have seted up in the wash bowl 161, wash the intracavity and install the filter screen section of thick bamboo 162 of vertical setting and be used for driving filter screen section of thick bamboo 162 pivoted third servo motor 163, brush hair 164 is installed to the inner peripheral round of filter screen section of thick bamboo 162, install the drain pipe 165 with washing the chamber intercommunication on the filter screen section of thick bamboo 162. The cleaning cavity is internally and rotatably connected with a threaded disc 166, the filter screen cylinder 162 is sleeved on the threaded disc 166 in a threaded manner, a second mounting cavity is formed in the cleaning cylinder 161, the third servo motor 163 is mounted in the second mounting cavity, and the output end of the third servo motor 163 is connected with the threaded disc 166.

In order to clean the amplitude transformer 84 and facilitate the next use, the second servo motor 85 can drive the rotary disc 86 to drive the electric slide rail 81 to rotate, so that the amplitude transformer 84 on the transducer 83 rotates to the position above the cleaning mechanism 16, then the electric push rod 19 drives the connecting block 18 to approach the amplitude transformer 84, so that the filter screen cylinder 162 in the cleaning cylinder 161 is sleeved on the amplitude transformer 84, the amplitude transformer 84 is in contact with the bristles 164 in the filter screen cylinder 162, then cleaning liquid is poured into the cleaning cylinder 161, the threaded disc 166 is driven by the third servo motor 163 to drive the filter screen cylinder 162 to rotate, the amplitude transformer 84 can be cleaned by the bristles 164 in the filter screen cylinder 162, and the cleaned sewage can be discharged through the drain pipe 165.

To facilitate cleaning of the bristles 164 in the screen cartridge 162, the screen cartridge 162 may be removed from the threaded plate 166, which facilitates cleaning of the bristles 164 in the screen cartridge 162.

In order to clean the dirt in the washing cylinder 161, the washing cylinder 161 can be rotated on the connecting block 18, so that the opening of the washing cylinder 161 faces downwards, and the structure is convenient for cleaning the dirt in the washing cylinder 161.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims

1. A cell crusher is characterized by comprising a base (1), wherein a rotating rod (2) and a first servo motor (3) used for rotating the rotating rod (2) are arranged on the base (1), a plurality of connecting rods (4) which are distributed in the circumferential direction are arranged on the rotating rod (2), a placing block (5) is arranged at one end of each connecting rod (4) far away from the rotating rod (2), a placing groove is arranged in the placing block (5), two fixing plates (6) are arranged on the placing block (5), the placing groove is positioned between the two fixing plates (6), a positioning frame (7) positioned above the placing groove and a driving piece for driving the positioning frame (7) to move in the vertical direction of the fixing plates (6) are respectively arranged at one opposite side of the two fixing plates (6), the cell crushing mechanism (8) for crushing cells is installed on the base (1).

2. A cell disruptor as claimed in claim 1, characterised in that: the fixing plate (6) is of an L-shaped structure, a rotating cavity is formed in the placing block (5), the driving piece comprises a gear (9), a threaded rod (10), a rack (11) and a sleeve (12), the gear (9) is rotatably connected in the rotating cavity, the threaded rod (10) is vertically connected to the gear (9), one end, away from the gear (9), of the threaded rod (10) is rotatably connected with the fixing plate (6) and penetrates through the placing block (5), an inserting cavity matched with the rack (11) and communicated with the rotating cavity is formed in the placing block (5), the rack (11) slidably penetrates through the inserting cavity, a plurality of racks meshed with the gear (9) are mounted on the rack (11), a vertically-arranged chute is formed in the fixing plate (6), the sleeve (12) is sleeved on the threaded rod (10), and a limiting block (13) slidably connected with the chute is mounted on the sleeve (12), the positioning frame (7) is arranged on the sleeve (12).

3. A cell disruptor as claimed in claim 2, characterised in that: locating rack (7) is including installing dead lever (71) on sleeve (12) and horizontal setting, it has telescopic link (72) of inserting smooth intracavity to have seted up smooth chamber and dead lever (71) in dead lever (71) and keep away from sleeve (12) one end, threaded connection has bolt (73) that compresses tightly with telescopic link (72) on dead lever (71), telescopic link (72) are close to one side of placing piece (5) and install fixture block (74) of U type structure, install two relative cotton blocks (75) that set up in fixture block (74).

4. A cell disruptor as claimed in claim 3, characterised in that: an elastic positioning piece for locking the container is arranged in the placing groove.

5. A cell disruptor as claimed in claim 4, characterised in that: elastic positioning spare includes a plurality of springs (14), a plurality of block rubber (15), and is a plurality of spring (14) are all installed in the standing groove and are the annular and distribute, and a plurality of block rubber (15) are installed respectively a plurality of on spring (14).

6. A cell disruptor as claimed in any of claims 1 to 5, characterised in that: the cell crushing mechanism (8) comprises an electric sliding rail (81), an installation rod (82), a transducer (83), an amplitude transformer (84), a second servo motor (85) and a rotary table (86), the electric sliding rail (81) is vertically installed on the base (1), the installation rod (82) is transversely installed on a sliding block of the electric sliding rail (81), the transducer (83) is installed at one end, away from the electric sliding rail (81), of the installation rod (82), the amplitude transformer (84) is installed at one side, close to the base (1), of the transducer (83), the rotary table (86) is installed at one end, close to the base (1), of the electric sliding rail (81), the rotary table (86) is rotatably connected with the base (1), a first installation cavity is formed in the base (1), the second servo motor (85) is installed in the first installation cavity, and the output end of the second servo motor (85) is connected with the rotary table (86), the transducer (83) is connected with an ultrasonic generator through a lead.

7. A cell disruptor as claimed in claim 6, characterised in that: and a cleaning mechanism (16) for cleaning the amplitude transformer (84) is arranged on the base (1).

8. A cell disruptor as claimed in claim 7, characterised in that: clean mechanism (16) are including wash bowl (161), install assembly jig (17) on base (1), install two connecting blocks (18) on assembly jig (17) and be used for driving electric putter (19) of two connecting block (18) vertical movements, wash bowl (161) set up between two connecting blocks (18) and rotate with two connecting blocks (18) and be connected, it washs the chamber to have seted up in wash bowl (161), wash the intracavity and install filter screen cylinder (162) of vertical setting and be used for driving filter screen cylinder (162) pivoted third servo motor (163), brush hair (164) are installed to the inner circumferential round in filter screen cylinder (162), install drain pipe (165) with washing chamber intercommunication on filter screen cylinder (162).

9. A cell disruptor as claimed in claim 8, characterised in that: the cleaning cavity is connected with a threaded disc (166) in a rotating mode, the filter screen cylinder (162) is sleeved on the threaded disc (166) in a threaded mode, a second mounting cavity is formed in the cleaning cylinder (161), the third servo motor (163) is mounted in the second mounting cavity, and the output end of the third servo motor (163) is connected with the threaded disc (166).

10. A cell disruptor as claimed in any of claims 7 to 9, characterised in that: the base (1) is of a cross structure, a third installation cavity is formed in the base (1), a first servo motor (3) is installed in the third installation cavity, and the output end of the first servo motor (3) is connected with the rotating rod (2).