CN113855222A - Regulating system of arrhythmia radio frequency catheter - Google Patents
Regulating system of arrhythmia radio frequency catheter Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0538—Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
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- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
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- A—HUMAN NECESSITIES
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- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
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Abstract
The invention discloses a regulating system of an arrhythmia radio frequency catheter, which comprises a signal acquisition module, a signal processing module, an amplifier module, a display module, a power selection module and an ablation electrode, wherein the signal acquisition module acquires impedance signals of a heart, the impedance signals are amplified and transmitted to the signal processing module through the amplifier module, the signal processing module processes and calculates the signals to obtain impedance information, and the power selection module selects the working power of the ablation electrode according to the processing result of the signal processing module; the display module is used for displaying the result of the cardiac impedance and the working power of the ablation electrode, and the ablation electrode carries out ablation treatment on the cardiac region. The invention can detect the impedance of the focus area in real time, judge the impedance value, and melt the focus area, thereby achieving the purpose of continuous ablation of the radio frequency catheter and improving the treatment effect.
Description
Technical Field
The invention belongs to the technical field of medical equipment, and particularly relates to a regulating system of an arrhythmia radio frequency catheter.
Background
With the development of biomedicine, the treatment of arrhythmia by using the radio frequency catheter technology is widely applied. The radiofrequency catheter for treating arrhythmia is used for ablating and blocking the most critical part causing arrhythmia by using radiofrequency energy of high-frequency sinusoidal alternating current with 300-1000 kilohertz, so that the arrhythmia is treated radically. The radio frequency catheter generates radio frequency current, so that high-speed ion vibration and friction are generated on surrounding tissues, the high-speed ion vibration and friction are converted into heat energy, the local tissue cells are subjected to thermal coagulation necrosis and denaturation, and from the pathological angle, when the temperature reaches above 60 ℃, protein in human tissues can change the characteristics due to heat, so that irreversible necrosis of the tissue cells is caused, and normal cell tissues still have the self-treatment recovery capability within the thermotherapy range of 43-60 ℃. In the radio frequency ablation treatment, the focal zone is thoroughly ablated, a better treatment effect can be achieved, and continuous ablation in the ablation process has important significance for treating arrhythmia.
The existing radio frequency catheter can not continuously ablate, and can easily damage normal tissue cells in the process of ablating the focal zone, thereby influencing the treatment effect.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a regulating system of an arrhythmia radio frequency catheter, which can detect the impedance of a focus area in real time, judge the impedance value, ablate aiming at the focus area, achieve the aim of continuously ablating by the radio frequency catheter and improve the treatment effect.
The invention provides the following technical scheme:
a regulating system of an arrhythmia radio frequency catheter comprises a signal acquisition module, a signal processing module, an amplifier module, a display module, a power selection module and an ablation electrode, wherein the signal acquisition module acquires impedance signals of a heart, the impedance signals are amplified and transmitted to the signal processing module through the amplifier module, the signal processing module processes and calculates the signals to obtain impedance information, and the power selection module selects the working power of the ablation electrode according to the processing result of the signal processing module; the display module is used for displaying the result of the cardiac impedance and the working power of the ablation electrode, and the ablation electrode carries out ablation treatment on the cardiac region.
Preferably, when the signal acquisition module acquires data, two electrodes are used for measurement, wherein one group of electrodes measures voltage signals, the other group of electrodes provides excitation current, and the acquired cardiac impedance signals are processed by an orthogonal adjustment algorithm to obtain the module value and phase angle information of the impedance signals.
Preferably, the exciting current adopts a sinusoidal constant current signal:
i=Asin（wt）；
a is the amplitude of the excitation signal, and w is the angular frequency;
detected voltage signal:
V（t）=A∣M∣sin（wt+β）；
m is the module value of the tissue to be measured, beta is the phase angle variation value.
Preferably, the impedance signal is processed by kalman filtering before being amplified, and the kalman filtering step includes: initializing filtering, establishing a discrete equation, estimating a system priori, updating measurement, updating a system posterior, and ending.
Preferably, the system further comprises a database, wherein the database stores training data, and the system performs model training on the training data in the database to obtain corresponding parameters.
Preferably, the training data is impedance data acquired from a normal part of the heart, and the acquired data is subjected to kalman filtering before the training data.
Preferably, the power selection module comprises a data processing module, the data processing module is connected with the signal processing module, the data processing module can read trained data in a database, compare the trained data with impedance information obtained by the signal processing module, and control the power selection module to select corresponding ablation power.
Preferably, the signal acquisition module is connected with the power module through a current protection circuit, and the system circuit is timely cut off when the current is abnormal.
Preferably, a Kalman digital algorithm model is established before the impedance signal is subjected to Kalman filtering processing, impedance signal data are imported into the Kalman model, two parameters of state noise and observation noise are set, and the value of the state noise parameter is small based on the condition that the impedance of the focus region is not changed in a short time.
Preferably, the amplifier module adopts a low offset voltage and low noise operational amplifier OPA333, has a low noise, low current, low offset voltage, rail-to-rail input and output mode, meets the requirement of heart rate offset radio frequency ablation, and the system adopts an ohm law mode to obtain the human body impedance.
Preferably, the current protection circuit mainly comprises a power switch tube and a load resistor, when the current is detected to be abnormal, the buzzer alarms and cuts off output, so that the safety and reliability of equipment are improved, and the power switch tube is VIPER12A and has a restarting function and overvoltage protection.
Preferably, the ablation electrode is connected with a clock circuit module, the clock circuit module provides a clock signal required by the ablation electrode, and the ablation electrode generates a corresponding ablation current according to the clock signal.
Preferably, a method of treating arrhythmia using a radio frequency catheter, comprising the steps of:
s1: establishing a database, collecting a comparison sample, detecting impedance of a normal part of the heart, collecting a signal of the normal part of the heart, establishing the database, using the database as the comparison sample and judging a focus part;
s2: judging a focus area, namely moving the radio frequency catheter to the focus area, extracting an impedance signal, and judging by combining a sample in a database;
s3: performing ablation treatment, namely performing ablation treatment on the changed point if the judgment result is the focus area point, and prompting if the judgment result is normal, wherein the ablation electrode does not perform treatment;
s4: and moving the ablation electrode, and moving the ablation electrode to the next part after the ablation treatment is finished, so as to judge and ablate the focal zone.
Compared with the prior art, the invention has the following beneficial effects:
(1) the adjusting system of the arrhythmia radio frequency catheter detects the impedance of a focus area in real time, judges the impedance value, can perform ablation on a focus area, achieves the aim of continuous ablation of the radio frequency catheter, and improves the treatment effect.
(2) According to the adjusting system of the arrhythmia radio frequency catheter, effective impedance signals are extracted by performing Kalman filtering processing on the impedance signals, the influence of noise is reduced, and the analysis precision of the impedance signals is improved.
(3) According to the adjusting system of the arrhythmia radio frequency catheter, the database model is established, and the extracted impedance signal in the focal region is compared with the database model, so that the condition of a signal acquisition point in the focal region is judged, the impedance analysis precision is further improved, the ablation treatment and the targeted ablation treatment can be accurately performed, and the ablation effect is improved.
(4) The invention relates to a regulating system of an arrhythmia radio frequency catheter, which adopts a current protection circuit, and when the current is detected to be abnormal, a buzzer alarms and cuts off the output, thereby improving the safety and the reliability of equipment.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a schematic diagram of the system architecture of the present invention.
Fig. 2 is a diagram of a current protection circuit of the present invention.
Fig. 3 is a circuit diagram of a signal acquisition module of the present invention.
Fig. 4 is a schematic diagram of a method of treating arrhythmia of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be described in detail and completely with reference to the accompanying drawings. It is to be understood that the described embodiments are only a few embodiments of the present invention, and not all embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
The first embodiment is as follows:
with reference to fig. 1 and 3, a system for adjusting an arrhythmia rf catheter includes a signal acquisition module, a signal processing module, an amplifier module, a display module, a power selection module, and an ablation electrode, where the signal acquisition module is connected to the amplifier module, the amplifier module is connected to the signal processing module, both the display module and the power selection module are connected to the signal processing module, the ablation electrode is connected to the power selection module, the signal acquisition module acquires an impedance signal of a heart, the impedance signal is amplified by the amplifier module and transmitted to the signal processing module, the signal processing module processes and calculates the signal to obtain impedance information, and the power selection module selects a working power of the ablation electrode according to a processing result of the signal processing module; the display module is used for displaying the result of the cardiac impedance and the working power of the ablation electrode, the ablation electrode carries out ablation treatment on a cardiac region, and the ablation electrode releases current to generate high temperature so as to denature and necrose cell protein in a lesion region.
When the signal acquisition module acquires data, two electrodes are used for measurement, one group of electrodes is used for measuring voltage signals, the other group of electrodes is used for providing exciting current, the acquired cardiac impedance signals are processed by an orthogonal adjustment algorithm to obtain the module value and phase angle information of the impedance signals, and the two groups of electrodes are used for measurement, so that the problem of uneven current distribution is avoided, the problem of electrode polarization is reduced, and the detection precision is improved. The exciting current adopts a sinusoidal constant current signal: i = asin (wt); a is the amplitude of the excitation signal, and w is the angular frequency; detected voltage signal: v (t) = a | sin (wt + β); m is the module value of the tissue to be measured, beta is the phase angle variation value.
The impedance signal is processed by Kalman filtering before amplification, and the Kalman filtering processing step comprises: initializing filtering, establishing a discrete equation, estimating a system priori, updating measurement, updating a system posterior, and ending. The impedance after Kalman filtering has the advantages of high stability and small error, and the filtered impedance signal is amplified by an amplifier.
The system also comprises a database, wherein training data are stored in the database, the system carries out model training on the training data in the database so as to obtain corresponding parameters, a data model is established, and the data model is used for comparing with signal data obtained in the ablation process and judging whether the ablation treatment is carried out at the point. The training data are impedance data acquired from normal positions of the heart, and before the training data, Kalman filtering processing is performed on the acquired data.
The power selection module comprises a data processing module, the data processing module is connected with the signal processing module, the data processing module can read trained data in a database, the trained data are compared with impedance information obtained by the signal processing module, and the power selection module is controlled to select corresponding ablation power.
As shown in fig. 2, the signal acquisition module is connected with the power supply module through the current protection circuit, and the system circuit is timely cut off when the current is abnormal, so that the stability and the safety of the system are ensured.
A Kalman digital algorithm model is established before impedance signals are subjected to Kalman filtering processing, impedance signal data are imported into the Kalman model, two parameters of state noise and observation noise are set, and the state noise parameters are small in value based on the condition that the impedance of a focus region is not changed in a short time, so that the Kalman filtering precision is improved, and the filtering effect is improved.
The amplifier module adopts a low offset voltage and low noise operational amplifier OPA333, has low noise, low current, low offset voltage and rail-to-rail input and output modes, meets the requirement of heart rate offset radio frequency ablation, and the system adopts an ohm law mode to obtain human body impedance. The current protection circuit mainly comprises a power switch tube and a load resistor, when the detected current is abnormal, a buzzer alarms and the output is cut off, so that the safety and the reliability of equipment are improved, and the power switch tube selects VIPER12A and has a restarting function and overvoltage protection.
Example two
With reference to fig. 1, a system for adjusting an arrhythmia rf catheter includes a signal acquisition module, a signal processing module, an amplifier module, a display module, a power selection module, and an ablation electrode, where the signal acquisition module is connected to the amplifier module, the amplifier module is connected to the signal processing module, both the display module and the power selection module are connected to the signal processing module, the ablation electrode is connected to the power selection module, the signal acquisition module acquires impedance signals of a heart, the impedance signals are amplified by the amplifier module and transmitted to the signal processing module, the signal processing module processes and calculates the signals to obtain impedance information, and the power selection module selects working power of the ablation electrode according to a processing result of the signal processing module; the display module is used for displaying the result of the cardiac impedance and the working power of the ablation electrode, the ablation electrode carries out ablation treatment on a cardiac region, and the ablation electrode releases current to generate high temperature so as to denature and necrose cell protein in a lesion region.
The impedance signal is processed by Kalman filtering before amplification, and the Kalman filtering processing step comprises: initializing filtering, establishing a discrete equation, estimating a system priori, updating measurement, updating a system posterior, and ending. The impedance after Kalman filtering has the advantages of high stability and small error, and the filtered impedance signal is amplified by an amplifier.
The system also comprises a database, wherein training data are stored in the database, the system carries out model training on the training data in the database so as to obtain corresponding parameters, a data model is established, and the data model is used for comparing with signal data obtained in the ablation process and judging whether the ablation treatment is carried out at the point. The training data are impedance data acquired from normal positions of the heart, and before the training data, Kalman filtering processing is performed on the acquired data.
The ablation electrode is connected with a clock circuit module, the clock circuit module provides a clock signal required by the ablation electrode, the ablation electrode generates corresponding ablation current according to the clock signal, and the ablation current is used for ablating the focus area.
EXAMPLE III
Referring to fig. 4, a method for treating arrhythmia using a radio frequency catheter comprises the following steps:
s1: establishing a database, collecting a comparison sample, detecting impedance of a normal part of the heart, collecting a signal of the normal part of the heart, establishing the database, using the database as the comparison sample and judging a focus part;
s2: judging a focus area, namely moving the radio frequency catheter to the focus area, extracting an impedance signal, and judging by combining a sample in a database;
s3: performing ablation treatment, namely performing ablation treatment on the changed point if the judgment result is the focus area point, and prompting if the judgment result is normal, wherein the ablation electrode does not perform treatment;
s4: and moving the ablation electrode, and moving the ablation electrode to the next part after the ablation treatment is finished, so as to judge and ablate the focal zone.
The device obtained by the technical scheme is an arrhythmia radio frequency catheter adjusting system, in the using process, firstly, impedance signals of normal parts are collected to serve as reference samples, a database model is established, then, impedance signals are collected and analyzed in a focus area, when the impedance signals are abnormal with signals in the database, the focus area can be judged, then, a preset power is selected by a power selection module, ablation treatment is carried out by using an ablation electrode, after ablation is finished, the next area is detected, judged and ablated, abnormal parts in the focus area can be ablated by adopting the arrhythmia radio frequency catheter adjusting system, normal tissues in the focus area cannot be damaged, and the treatment effect of the radio frequency catheter is greatly improved.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and it will be apparent to those skilled in the art that various modifications and variations can be made in the present invention; any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (7)
1. A regulating system of an arrhythmia radio frequency catheter is characterized by comprising a signal acquisition module, a signal processing module, an amplifier module, a display module, a power selection module and an ablation electrode, wherein the signal acquisition module acquires impedance signals of a heart, the impedance signals are amplified by the amplifier module and transmitted to the signal processing module, the signal processing module processes and calculates the signals to obtain impedance information, and the power selection module selects the working power of the ablation electrode according to the processing result of the signal processing module; the display module is used for displaying the result of the cardiac impedance and the working power of the ablation electrode, and the ablation electrode carries out ablation treatment on the cardiac region.
2. The system of claim 1, wherein the signal acquisition module is configured to acquire data using two electrodes, one of the electrodes is configured to measure a voltage signal, the other electrode is configured to provide an excitation current, and the acquired cardiac impedance signal is processed by a quadrature modulation algorithm to obtain a modulus and a phase angle of the impedance signal.
3. The system for regulating an arrhythmic radiofrequency catheter, according to claim 2, wherein the excitation current is a sinusoidal constant current signal:
i=Asin（wt）；
a is the amplitude of the excitation signal, and w is the angular frequency;
detected voltage signal:
V（t）=A∣M∣sin（wt+β）；
m is the module value of the tissue to be measured, beta is the phase angle variation value.
4. The system for conditioning an arrhythmic radiofrequency catheter of claim 1, wherein the impedance signal is processed by kalman filtering before amplification, the kalman processing step comprising: initializing filtering, establishing a discrete equation, estimating a system priori, updating measurement, updating a system posterior, and ending.
5. The system for regulating an arrhythmic rf catheter, according to claim 1, further comprising a database, wherein the database stores training data, and the system performs model training on the training data in the database to obtain the corresponding parameters.
6. The system for regulating an arrhythmic rf catheter according to claim 5, wherein the power selection module comprises a data processing module, the data processing module is connected to the signal processing module, the data processing module can read the trained data in the database, compare the trained data with the impedance information obtained by the signal processing module, and control the power selection module to select the corresponding ablation power.
7. The system for regulating an arrhythmic radiofrequency catheter, according to claim 1, wherein the signal acquisition module is connected with the power supply module through a current protection circuit, and the system circuit is cut off in time when the current is abnormal.
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| CN114983557A (en) * | 2022-04-29 | 2022-09-02 | 天津市鹰泰利安康医疗科技有限责任公司 | Device and method for catheter-mediated irreversible electroporation ablation of tissue |
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| CN113476136A (en) * | 2021-06-29 | 2021-10-08 | 苏州心岭迈德医疗科技有限公司 | Pulse field ablation control method and system |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114983557A (en) * | 2022-04-29 | 2022-09-02 | 天津市鹰泰利安康医疗科技有限责任公司 | Device and method for catheter-mediated irreversible electroporation ablation of tissue |
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