CN113832026A - Collagen peptide low temperature enzymolysis system - Google Patents
Collagen peptide low temperature enzymolysis system Download PDFInfo
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- CN113832026A CN113832026A CN202111191798.9A CN202111191798A CN113832026A CN 113832026 A CN113832026 A CN 113832026A CN 202111191798 A CN202111191798 A CN 202111191798A CN 113832026 A CN113832026 A CN 113832026A
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- 102000008186 Collagen Human genes 0.000 title claims abstract description 114
- 108010035532 Collagen Proteins 0.000 title claims abstract description 114
- 229920001436 collagen Polymers 0.000 title claims abstract description 112
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 109
- 238000003756 stirring Methods 0.000 claims abstract description 133
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 118
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 30
- 229910021389 graphene Inorganic materials 0.000 claims abstract description 30
- 238000010438 heat treatment Methods 0.000 claims abstract description 18
- 230000003068 static effect Effects 0.000 claims abstract description 13
- 239000012530 fluid Substances 0.000 claims abstract description 12
- 239000012780 transparent material Substances 0.000 claims abstract description 8
- 239000000110 cooling liquid Substances 0.000 claims description 17
- 238000009434 installation Methods 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 6
- 238000004891 communication Methods 0.000 claims description 5
- 238000007789 sealing Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 102000004190 Enzymes Human genes 0.000 description 53
- 108090000790 Enzymes Proteins 0.000 description 53
- 229940088598 enzyme Drugs 0.000 description 53
- 239000000203 mixture Substances 0.000 description 27
- 230000000694 effects Effects 0.000 description 19
- 229910002804 graphite Inorganic materials 0.000 description 14
- 239000010439 graphite Substances 0.000 description 14
- -1 graphite alkene Chemical class 0.000 description 14
- 102000004196 processed proteins & peptides Human genes 0.000 description 9
- 150000003384 small molecules Chemical class 0.000 description 7
- 230000003197 catalytic effect Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 238000002156 mixing Methods 0.000 description 6
- 230000008569 process Effects 0.000 description 5
- 102000029816 Collagenase Human genes 0.000 description 4
- 108060005980 Collagenase Proteins 0.000 description 4
- 239000004365 Protease Substances 0.000 description 4
- 230000004071 biological effect Effects 0.000 description 4
- 229920001184 polypeptide Polymers 0.000 description 4
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 3
- 108091005804 Peptidases Proteins 0.000 description 3
- 102000035195 Peptidases Human genes 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 230000002457 bidirectional effect Effects 0.000 description 3
- 229940098773 bovine serum albumin Drugs 0.000 description 3
- 229960002424 collagenase Drugs 0.000 description 3
- 235000019419 proteases Nutrition 0.000 description 3
- 239000002826 coolant Substances 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 238000010030 laminating Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 108090000526 Papain Proteins 0.000 description 1
- 102000057297 Pepsin A Human genes 0.000 description 1
- 108090000284 Pepsin A Proteins 0.000 description 1
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- 239000002253 acid Substances 0.000 description 1
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
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- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
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- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
- C12M27/08—Stirrer or mobile mixing elements with different stirrer shapes in one shaft or axis
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- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
- C12M41/24—Heat exchange systems, e.g. heat jackets or outer envelopes inside the vessel
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Abstract
The invention belongs to the technical field of collagen peptide production, and particularly relates to a low-temperature enzymolysis system for collagen peptide, which comprises an enzymolysis container, wherein the enzymolysis container comprises a columnar container, a heating ball positioned at the rotation center of the columnar container, a mounting frame, a graphene layer, a first spherical shell, a first pipe, a second spherical shell and a second pipe; a plurality of stirring blades are uniformly distributed on the second spherical shell, and all the stirring blades are positioned on the same horizontal plane; a first water pipe is arranged between the first pipe and the second pipe; the first water pipe comprises a first static pipe, a first moving pipe and a fluid slip ring; the first moving pipe penetrates through a gap between the first spherical shell and the second spherical shell and is wound at the gap, and the first moving pipe is wound and then sequentially penetrates into each stirring blade, penetrates out of the gap between the first pipe and the second pipe and is communicated to the first cavity; the first spherical shell, the second spherical shell, the stirring blade and the first water pipe are all made of transparent materials; the technical scheme of the invention can solve the problem of low-temperature enzymolysis rate of the existing collagen peptide.
Description
Technical Field
The invention belongs to the technical field of collagen peptide production, and particularly relates to a low-temperature enzymolysis system for collagen peptide.
Background
Collagen is a white, opaque and unbranched fibrous structure protein, and the unique triple-strand supercoiled structure of collagen makes it have very stable chemical properties, and weak acid hardly decomposes it. Therefore, it is difficult to be directly digested and utilized by human body. However, after collagen is hydrolyzed to form collagen polypeptide with smaller molecular weight, the bioavailability of the collagen polypeptide can be obviously improved, and the collagen polypeptide is more beneficial to being absorbed and utilized by human bodies. The principle of hydrolyzing collagen protein by an enzymolysis method to prepare collagen peptide is to hydrolyze collagen protein by protease, such as collagenase, pepsin, papain and the like, so as to obtain polypeptide.
The hydrolysis temperature of the existing collagen enzymolysis mode is mostly in the range of 40-60 ℃, the activity of protease is strongest in the temperature range, but the hydrolyzed small molecular collagen peptide easily loses the biological activity in the temperature range; if the temperature of the low-temperature enzymolysis of the collagen peptide is reduced, the biological activity of the collagen peptide is ensured, the activity of collagenase is reduced, and the low-temperature enzymolysis rate of the collagen peptide is further reduced.
Disclosure of Invention
In order to make up for part of the defects in the prior art, the invention provides a collagen peptide low-temperature enzymolysis system which is used for improving the low-temperature enzymolysis rate of collagen peptide.
The technical scheme adopted by the invention for solving the technical problems is as follows: a low-temperature enzymolysis system for collagen peptide comprises an enzymolysis container, wherein the enzymolysis container comprises a columnar container, a heating ball positioned at the rotation center of the columnar container and a mounting frame; the heating ball is sleeved with a graphene layer; a first spherical shell is sleeved outside the graphene layer, and the inner wall of the first spherical shell is not in contact with the outer wall of the graphene layer; a first pipe is arranged at the upper end of the first spherical shell, an installation frame is arranged on the side part of the columnar container, and the installation frame is in an inverted L shape; one end of the mounting frame is fixedly connected with the side part of the columnar container, the other end of the mounting frame extends to the top end of the first pipe, and the first pipe is fixed with the side part of the columnar container through the mounting frame; the first spherical shell is also sleeved with a second spherical shell, and the inner wall of the second spherical shell is not contacted with the outer wall of the first spherical shell; the upper end of the second spherical shell is connected with a second pipe; the first tube is positioned in the second tube, and the first tube and the second tube are not contacted with each other; the second pipe extends out of the upper end of the columnar container, and a gear ring is fixedly arranged on the second pipe outside the columnar container; the second pipe is rotationally connected with the columnar container; a motor is arranged on the side surface of the columnar container; the motor drives the gear ring to rotate through the gear belt; a plurality of stirring blades are uniformly distributed on the outer surface of the second spherical shell, and all the stirring blades are positioned on the same horizontal plane; a first water pipe is arranged between the first pipe and the second pipe; the first water pipe comprises a first static pipe, a first moving pipe and a fluid slip ring; the fluid slip ring comprises an upper annular cover and a lower annular shell capable of rotating relative to the upper annular cover in a sealing mode, and the upper annular cover and the lower annular shell enclose to form a first cavity; the first static pipe penetrates through the upper annular cover and is communicated with the first cavity; the first moving pipe penetrates through the lower annular shell and is communicated with the first cavity; the side wall of the lower annular shell is fixedly connected with the inner wall of the second pipe;
the upper annular cover is fixedly connected with the outer wall of the first pipe through a bracket; one end of the first moving pipe is communicated with the first cavity, the other end of the first moving pipe penetrates through a gap between the first spherical shell and the second spherical shell and is wound at the gap, the first moving pipe is sequentially inserted into each stirring blade after being wound, penetrates out of the gap between the first pipe and the second pipe and is communicated with the first cavity again; the first spherical shell, the second spherical shell, the stirring blade and the first water pipe are all made of transparent materials; the upper end of the columnar container is provided with a raw material inlet, and the side wall of the lower end of the columnar container is provided with a material outlet.
A second water pipe is arranged between the first pipe and the second pipe; the second water pipe and the first water pipe are arranged in parallel and are fixedly connected with each other; a second cavity concentric with the first cavity is further isolated in the fluid sliding ring, the inner diameter of the first cavity is larger than the outer diameter of the second cavity, and the second water pipe comprises a second static pipe and a second moving pipe; the second static pipe penetrates through the upper annular cover and is communicated with the second cavity; the second moving pipe penetrates through the lower annular shell and is communicated with the second cavity; a first water pipe and a second water pipe in the stirring blade are arranged in a fitting manner; the second water pipe is made of transparent materials; the flow direction of the cooling liquid in the first water pipe is opposite to that of the cooling liquid in the second water pipe.
The first water pipe and the second water pipe in the gap between the first spherical shell and the second spherical shell are arranged in parallel contact, the contact surface of the first water pipe and the second water pipe which are in parallel contact penetrates through the lower part of the rotation center of the second water pipe, and the first water pipe and the second water pipe which are positioned below the rotation center of the second water pipe are communicated; a first rotating shaft is arranged at the communication part of the first water pipe and the second water pipe; the one end equipartition of a pivot has drive blade, and the other end equipartition of a pivot has a plurality of stirring pieces, drive blade is located the central authorities of a water pipe and No. two water pipe intercommunication departments.
The stirring piece overcoat is equipped with barrel-shaped casing, casing and No. two spherical shell fixed connection, the stirring piece is the heliciform, the top of casing evenly is provided with a plurality of conveyer pipes, the one end and the inside UNICOM of barrel-shaped casing of conveyer pipe, the other end of conveyer pipe is located the top of No. two spherical shells.
The stirring blade is provided with a turbulent flow pipe; the turbulent flow tubes are arranged along the length direction of the stirring blade, one ends of the turbulent flow tubes are positioned at the edges of the stirring blade, and the tube openings of the turbulent flow tubes face the direction tangential to the rotation direction of the stirring blade; the other end of the turbulent flow pipe points to the stirring sheet along the surface of the second spherical shell.
The surfaces of the stirring blades and the stirring sheets are adhered with soft films.
The invention has the following beneficial effects:
1. in the scheme, on one hand, the motor drives the gear ring to rotate through the gear belt, so that the stirring blade is driven to rotate, the collagen peptide and the enzyme are fully mixed, and the collagen peptidase hydrolysis rate is improved; on the other hand, through set up graphite alkene layer in spherical shell, the graphite alkene layer that makes to be heated launches the enzyme catalysis of far infrared ray to can improve the efficiency and the speed of enzymolysis, and then improve the speed of collagen peptide low temperature enzymolysis.
2. In this scheme, a water pipe is through the clearance between a spherical shell and No. two spherical shells, can completely cut off or reduce graphite alkene layer and give off the heat to the outer collagen peptide of No. two spherical shells and the mixture of enzyme, the light that makes the graphite alkene layer of heating distribute is cooled down when passing a water pipe or closing on a water pipe, avoid or reduce the collagen peptide and the too high problem of enzyme temperature that close on No. two casing departments, and then reduced the influence that graphite alkene layer generates heat to collagen peptide and enzyme temperature, thereby make the collagen peptide enzymolysis process be in the comparatively mild environment of a temperature, be favorable to improving the active micromolecule collagen peptide of low temperature enzymolysis of collagen peptide, satisfy the actual production demand.
3. According to the scheme, the soft films are attached to the upper surfaces of the stirring blades and the stirring sheets, so that the surfaces of the stirring blades and the stirring sheets are soft, and the damage degree of enzymolysis to collagen peptides can be reduced when the stirring blades and the stirring sheets are stirred; in addition, when wasing stirring vane and stirring piece, can tear the mantle, wash the mantle to reduce the abluent degree of difficulty of stirring vane and stirring piece corner.
Drawings
The invention will be further explained with reference to the drawings.
FIG. 1 is a general view of the structure of an enzymatic hydrolysis vessel;
FIG. 2 is a view showing the internal structure of the enzymolysis vessel;
FIG. 3 is a sectional view showing the internal structure of the enzymolysis container;
FIG. 4 is a schematic view of the connection of the fluid slip ring with the first water pipe and the second water pipe;
FIG. 5 is a partial schematic view of the arrangement of the driving vanes at the communication position of the first water pipe and the second water pipe;
in the figure: columnar container 1, raw materials entry 11, material outlet 12, heating ball 2, mounting bracket 21, graphite alkene layer 22, a spherical shell 23, No. one pipe 24, No. two spherical shells 25, No. two pipes 26, gear ring 27, motor 28, stirring vane 3, a water pipe 4, No. one quiet pipe 41, No. one move pipe 42, fluid sliding ring 5, upper annular cover 51, lower annular housing 52, No. one cavity 53, support 54, No. two water pipes 6, No. two cavities 61, pivot 7, drive blade 71, stirring piece 72, casing 73, conveyer pipe 74, stirring vane 3, vortex pipe 75.
Detailed Description
In order to make the technical means, the creation features, the achievement purposes and the effects of the invention easy to understand, the invention is further explained below by combining the detailed description and the attached drawings 1-5 in the specification.
The technical scheme adopted by the invention for solving the technical problems is as follows: a low-temperature enzymolysis system for collagen peptide comprises a raw material processing device, a separation container, an enzymolysis container, an inactivation container, a decoloration container, a filtering device and a drying device, wherein the enzymolysis container is used for carrying out low-temperature enzymolysis on the collagen peptide; the enzymolysis container comprises a columnar container 1, a heating ball 2 positioned at the rotation center of the columnar container 1 and a mounting rack 21; the heating ball 2 is sleeved with a graphene layer 22; a first spherical shell 23 is sleeved outside the graphene layer 22, and the inner wall of the first spherical shell 23 is not in contact with the outer wall of the graphene layer 22; a first pipe 24 is arranged at the upper end of the first spherical shell 23, an installation frame 21 is arranged at the side part of the columnar container 1, and the installation frame 21 is in an inverted L shape; one end of the mounting frame 21 is fixedly connected with the side part of the columnar container 1, the other end of the mounting frame 21 extends to the top end of the first tube 24, and the first tube 24 is fixed with the side part of the columnar container 1 through the mounting frame 21; a second spherical shell 25 is further sleeved outside the first spherical shell 23, and the inner wall of the second spherical shell 25 is not in contact with the outer wall of the first spherical shell 23; the upper end of the second spherical shell 25 is connected with a second pipe 26; the first tube 24 is positioned inside the second tube 26, and the first tube and the second tube are not contacted with each other; the second pipe 26 extends out of the upper end of the columnar container 1, and a gear ring 27 is fixedly arranged on the second pipe 26 positioned outside the columnar container 1; the second pipe 26 is rotatably connected with the columnar container 1; the side surface of the columnar container 1 is provided with a motor 28; the motor 28 drives the gear ring 27 to rotate through a gear belt; a plurality of stirring blades 3 are uniformly distributed on the outer surface of the second spherical shell 25, and each stirring blade 3 is positioned on the same horizontal plane; a first water pipe 4 is arranged between the first pipe 24 and the second pipe 26; the first water pipe 4 comprises a first static pipe 41, a first moving pipe 42 and a fluid slip ring 5; the fluid slip ring 5 comprises an upper annular cover 51 and a lower annular shell 52 capable of rotating in a sealing manner relative to the upper annular cover 51, wherein the upper annular cover 51 and the lower annular shell 52 enclose a first cavity 53; the first number static pipe 41 penetrates through the upper annular cover 51 and is communicated with the first number cavity 53; the first number pipe 42 penetrates through the lower annular shell 52 and is communicated with the first number cavity 53; the side wall of the lower annular shell 52 is fixedly connected with the inner wall of the second pipe 26;
the upper annular cover 51 is fixedly connected with the outer wall of the first tube 24 through a bracket 54; one end of the first moving pipe 42 is communicated with the first cavity 53, the other end of the first moving pipe passes through a gap between the first spherical shell 23 and the second spherical shell 25 and is coiled at the gap, and the first moving pipe 42 is sequentially threaded into each stirring blade 3 after being coiled, penetrates out of the gap between the first pipe 24 and the second pipe 26 and is communicated with the first cavity 53 again; the first spherical shell 23, the second spherical shell 25, the stirring blades 3 and the first water pipe 4 are all made of transparent materials; the upper end of the columnar container 1 is provided with a raw material inlet 11, and the side wall of the lower end of the columnar container 1 is provided with a material outlet 12;
when the device works, the raw material inlet 11 is used for introducing collagen peptide and enzyme corresponding to the decomposition of the collagen peptide into the columnar container 1, the enzyme is collagenase, and the collagen peptide is decomposed by the enzyme; the collagen peptide is subjected to enzymolysis in a high-temperature environment with optimal enzyme activity, so that the hydrolyzed small-molecule collagen peptide easily loses biological activity and is contrary to the required small-molecule collagen peptide with biological activity, and if the collagen peptide is subjected to enzymolysis in a low-temperature environment lower than 40 ℃, the activity of the enzyme for decomposing the collagen peptide is limited at the temperature, so that the low-temperature enzymolysis rate of the collagen peptide is reduced; in the scheme, in order to solve the problem of low-temperature enzymolysis rate of the collagen peptide, on one hand, the motor 28 drives the gear ring 27 to rotate through the gear belt, so as to drive the stirring blade 3 to rotate, thereby realizing the full mixing of the collagen peptide and the enzyme and being beneficial to improving the enzymolysis rate of the collagen peptide; on the other hand, the graphene layer 22 is arranged in the first spherical shell 23, and the graphene layer 22 is heated by the heating ball 2, so that the heated graphene layer 22 emits far infrared rays to have a catalytic effect on enzymes, and the first spherical shell 23, the second spherical shell 25, the stirring blades 3 and the first water pipe 4 are all made of transparent materials, so that the barrier of the graphene layer 22 for emitting far infrared rays can be reduced, the enzymolysis efficiency and speed can be improved, and the low-temperature enzymolysis speed of collagen peptide can be further improved;
the heating of the graphene layer 22 inevitably affects the temperature of the mixture of the collagen peptide and the enzyme, so that the temperature of the mixture of the collagen peptide and the enzyme is increased, the graphene layer 22 is not required to be heated in the enzymolysis process of the collagen peptide, and if the graphene layer 22 continuously heats to continuously increase the temperature of the collagen peptide, the collagen peptide of the small molecule is inactivated; the present case uses graphite alkene layer 22 is in order to utilize graphite alkene layer 22 to be heated the after-emitting far infrared to the catalytic action of enzyme, and graphite alkene layer 22 is heated the temperature low, and the far infrared that emits is comparatively faint, and graphite alkene layer 22 is heated the temperature high, and the far infrared intensity that emits is high. If bovine serum albumin is subjected to enzymolysis, under proper conditions, the required enzymolysis result can be obtained within several hours without the assistance of far infrared rays, and under proper conditions, the bovine serum albumin is subjected to enzymolysis by far infrared rays-assisted bovine serum albumin protease, the enzymolysis time which originally needs several hours can be shortened to dozens of minutes, and the results of the two are equivalent, so that the far infrared rays have better catalytic action on enzymes, the enzymolysis speed of collagen peptides can be greatly improved, in the scheme, the higher temperature carried by the graphene layer 22 when emitting stronger far infrared rays is inconsistent with the loss of activity of small-molecule collagen peptides due to the rise of temperature, and the key for solving the contradiction is that the influence of the higher temperature carried by the graphene layer 22 on the small-molecule collagen peptides is reduced, and the problem is solved, the low-temperature enzymolysis speed of the collagen peptide can be greatly improved under the assistance of far infrared rays to enzymes. In the scheme, on one hand, the first spherical shell 23 and the second spherical shell 25 are arranged, and a gap exists between the first spherical shell 23 and the second spherical shell 25, so that most of heat emitted by the graphene layer 22 is isolated, and the influence of heating of the graphene layer 22 on collagen peptide is reduced; on the other hand, the first water pipe 4 is arranged in the stirring blade 3, and the cooling liquid is introduced into the first water pipe 4, so that the effect of the stirring blade 3 on cooling the mixture of the collagen peptide and the enzyme in the stirring process is realized, the heating effect of the graphene layer 22 on the mixture of the collagen peptide and the enzyme is relieved, and the influence of the heating of the graphene layer 22 on the collagen peptide is reduced; in addition, the first water pipe 4 of the scheme can further reduce or isolate the heat conduction of the graphene layer 22 to the mixture of the collagen peptide and the enzyme outside the second spherical shell 25 through the gap between the first spherical shell 23 and the second spherical shell 25, and the heat emitted by the heated graphene layer 22 is absorbed or blocked when the first water pipe 4 or the first water pipe 4 is close to, so that the problem of overhigh temperature of the collagen peptide and the enzyme at the position close to the second shell 73 is avoided or reduced, and the influence of the heating of the graphene layer 22 on the temperature of the collagen peptide and the enzyme is further reduced; if the first water pipe 4 is not arranged between the first spherical shell 23 and the second spherical shell 25, the heat emitted from the heated graphene layer 22 cannot be temperature filtered by the first water pipe 4, so that the portion of the mixture of collagen peptides and enzymes adjacent to the graphene layer 22 is in a state of higher temperature, therefore, the first water pipe 4 is arranged between the first spherical shell 23 and the second spherical shell 25, the heat emitted by the graphene layer 22 can be effectively filtered, therefore, the enzymolysis process of the collagen peptide is in a mild environment, the low-temperature enzymolysis of the collagen peptide is facilitated to be improved, the active small-molecular collagen peptide is obtained, the actual production requirement is met, and after the low-temperature enzymolysis of the collagen peptide is completed, the material outlet 12 is formed in the side wall of the lower end of the columnar container 1 and is taken out.
As one embodiment of the scheme, a second water pipe 6 is arranged between the first pipe 24 and the second pipe 26; the second water pipe 6 and the first water pipe 4 are arranged in parallel and are fixedly connected with each other; a second cavity 61 concentric with the first cavity 53 is further isolated from the fluid slip ring 5, the inner diameter of the first cavity 53 is larger than the outer diameter of the second cavity 61, and the second water pipe 6 comprises a second static pipe and a second moving pipe; the second static pipe penetrates through the upper annular cover 51 and is communicated with the second cavity 61; the second number pipe passes through the lower annular housing 52 and communicates with the second number cavity 61; a first water pipe 4 and a second water pipe 6 in the stirring blade 3 are arranged in a fitting manner; the second water pipe 6 is made of transparent materials; the flow direction of the cooling liquid in the first water pipe 4 is opposite to that of the cooling liquid in the second water pipe 6;
during operation, because the first water pipe 4 is close to the surface of the first spherical shell 23, the graphene layer 22 and the heating ball 2 are arranged in the first spherical shell 23, the temperature of the cooling liquid at the inlet end of the first water pipe 4 is higher than that of the cooling liquid at the outlet end of the first water pipe 4 due to the heating of the heating ball 2, so that the temperature of the cooling liquid in the first water pipe 4 is uneven, the temperature difference is formed between the collagen peptide and the enzyme mixture at different positions in the cylindrical container 1, and the collagen peptide of small molecules hydrolyzed out easily loses bioactivity due to overhigh local temperature, and the low-temperature enzymolysis process of the collagen peptide is influenced; in the present case, set up No. two water pipes 6 that the coolant liquid flow direction is opposite through the side at a water pipe 4, and No. 4 water pipes 6 laminating in the stirring vane 3 are arranged, can make a water pipe 4 and No. two water pipes 6 carry out the heat exchange under the state that the laminating was arranged, thereby reduce the temperature fluctuation range of coolant liquid in a water pipe 4 and No. two water pipes 6, thereby make the mixture difference in temperature of the collagen peptide of different positions and enzyme reduce in the columnar container 1, be favorable to maintaining the stability of the mixture temperature of collagen peptide and enzyme, thereby improve the low temperature enzymolysis effect of collagen peptide.
As one embodiment of the scheme, the first water pipe 4 and the second water pipe 6 in the gap between the first spherical shell 23 and the second spherical shell 25 are arranged in parallel in a contact manner, the contact surface of the first water pipe 4 and the second water pipe 6 in parallel contact penetrates through the lower part of the rotation center of the second pipe 26, and the first water pipe 4 and the second water pipe 6 positioned below the rotation center of the second pipe 26 are communicated; a first rotating shaft 7 is arranged at the communication part of the first water pipe 4 and the second water pipe 6; one end of the first rotating shaft 7 is uniformly provided with a driving blade 71, the other end of the first rotating shaft 7 is uniformly provided with a plurality of stirring blades 72, the driving blade 71 is positioned in the center of the communication part of the first water pipe 4 and the second water pipe 6, one half of the driving blade 71 is positioned in the first water pipe 4, and the other half of the driving blade 71 is positioned in the second water pipe 6; the stirring sheet 72 is located outside the second spherical shell 25, and the stirring sheet 72 is driven by the driving blade 71 to rotate and stir below the second spherical shell 25. When the bidirectional water pump works, because the cooling liquid in the first water pipe 4 and the second water pipe 6 flows in the reverse direction, the cooling liquid in the first water pipe 4 impacts the driving blade 71 in the first water pipe 4, and the cooling liquid in the second water pipe 6 impacts the driving blade 71 in the second water pipe 6 in the reverse direction, so that the driving blade 71 rotates, the higher the flow velocity of the cooling liquid in the first water pipe 4 and the second water pipe 6 is, the higher the rotating speed of the driving blade 71 is, and the first water pipe 4 and the second water pipe 6 drive the cooling liquid through different water pumps, wherein the forward rotation of the blades of the bidirectional water pump can drive the cooling liquid to flow in the forward direction, and the reverse rotation of the blades of the bidirectional water pump can drive the cooling liquid to flow in the reverse direction; under the driving of the driving blade 71, the coaxial stirring blades 72 are rotated, so that the stirring blades 72 have a stirring effect; stir collagen peptide and enzyme simultaneously through stirring piece 72 and stirring vane 3, on the one hand, the intensive mixing of collagen peptide and enzyme has been improved, make the enzymolysis effect of collagen peptide low temperature improve, on the other hand, make the mixture temperature of collagen peptide and enzyme more even, avoid the local temperature of the mixture of collagen peptide and enzyme to rise and lead to the problem emergence of local collagen peptide deactivation, in addition, stir collagen peptide and enzyme simultaneously through stirring piece 72 and stirring vane 3, make the far infrared that the enzyme can be sent by graphite alkene layer 22 shine, the catalytic effect of enzyme has been improved, and then make the enzymolysis efficiency of collagen peptide low temperature improve. When the stirring piece 72 and the stirring blade 3 rotate forward or backward and the rotating speeds are different, multiple stirring forms exist in the scheme, for example, when the rotating directions of the stirring piece 72 and the stirring blade 3 are the same, the speed of the stirring piece 72 is greater than that of the stirring blade 3; if the rotation directions of the stirring blades 72 and the stirring blades 3 are the same, the speed of the stirring blades 72 is lower than that of the stirring blades 3; if the rotation direction of the stirring blade 72 is opposite to that of the stirring blade 3, the speed of the stirring blade 72 is higher than that of the stirring blade 3; if the rotation direction of the stirring blade 72 is opposite to that of the stirring blade 3, the speed of the stirring blade 72 is lower than that of the stirring blade 3; the multiple stirring modes can adopt one or more stirring modes to mix the collagen peptide and the enzyme according to actual requirements, so that the stirring effect is improved; and when the rotation direction of the stirring sheet 72 is opposite to that of the stirring blade 3, the mixture of the collagen peptide and the enzyme at the position of the stirring sheet 72 and the mixture of the collagen peptide and the enzyme at the position of the stirring blade 3 reversely flow, and the effect of better turbulent flow mixing stirring is achieved, so that the effect of low-temperature enzymolysis of the collagen peptide is improved.
As one embodiment of the present disclosure, a barrel-shaped housing 73 is sleeved outside the stirring blade 72, the housing 73 is fixedly connected to the second spherical shell 25, the stirring blade 72 is spiral, a plurality of delivery pipes 74 are uniformly arranged on the top of the housing 73, one end of each delivery pipe 74 is communicated with the inside of the barrel-shaped housing 73, and the other end of each delivery pipe 74 is located at the top end of the second spherical shell 25.
During operation, stirring piece 72 spiral rotates, the mixture spiral of collagen peptide and enzyme in the promotion casing 73 rotates, and then in being impressed the conveyer pipe 74 on casing 73 top, thereby the mixture of collagen peptide and enzyme in the promotion casing 73 flows to No. two spherical shell 25 tops, No. two interior graphite alkene layer 22 that has heated of spherical shell 25, graphite alkene layer 22 that is heated distributes far infrared, can improve the catalytic action of enzyme, thereby the mixture of collagen peptide and enzyme of No. two spherical shell 25 tops and bottom has been promoted on the one hand flows and mixes, improve the effect of collagen peptide low temperature enzymolysis, on the other hand, under the far infrared's that graphite alkene layer 22 distributes effect, the catalytic action of enzyme has been improved, and further improvement collagen peptide low temperature enzymolysis's effect.
As an embodiment of the present disclosure, the stirring blade 3 is provided with a turbulent flow tube 75; the turbulent flow pipe 75 is arranged along the length direction of the stirring blade 3, one end of the turbulent flow pipe 75 is positioned at the edge of the stirring blade 3, and the pipe orifice of the turbulent flow pipe 75 faces the rotation direction tangential to the stirring blade 3; the other end of the turbulent flow tube 75 is directed to the stirring blade 72 along the surface of the second spherical shell 25.
During operation, when the stirring blade 3 rotates, the stirring blade 3 drives the turbulent flow tube 75 thereon to rotate together, so that the mixture of the collagen peptide and the enzyme is poured into the turbulent flow tube 75 and flows out from the other end of the turbulent flow tube 75, and the mixture of the collagen peptide and the enzyme at the edge of the stirring blade 3 is conveyed to the second spherical shell 25, and under the stirring of the stirring blade 3, the mixture of the collagen peptide and the enzyme at the edge of the stirring blade 3 is continuously conveyed to the stirring sheet 72 below the second spherical shell 25, so that the mixing of the collagen peptide and the enzyme is better promoted, the temperature of the mixture of the collagen peptide and the enzyme is more uniform, and the low-temperature enzymolysis effect of the collagen peptide is improved.
When the mixture of the collagen peptide and the enzyme at the edge of the stirring blade 3 is conveyed to the stirring sheet 72 at the second spherical shell 25, the mixture of the collagen peptide and the enzyme can be stirred for the second time, so that the effect of low-temperature enzymolysis of the collagen peptide is promoted;
meanwhile, under the spiral stirring of the stirring sheet 72, partial mixture of the collagen peptide and the enzyme is spirally conveyed into the conveying pipe 74, under the continuous conveying of the stirring sheet 72, the mixture of the collagen peptide and the enzyme in the shell 73 can be conveyed to the top end of the second spherical shell 25, so that the sufficient flowing and mixing of the mixture of the collagen peptide and the enzyme above and below the second spherical shell 25 are promoted, the mixture of the collagen peptide and the enzyme at the edge of the stirring blade 3 is also promoted to be conveyed to the stirring sheet 72 and to the top end of the second spherical shell 25, the sufficient mixing of the collagen peptide and the enzyme and the uniformity of temperature distribution are improved, and the low-temperature enzymolysis rate of the collagen peptide is further improved.
As an example of the present embodiment, a soft film is attached to the surfaces of the stirring blade 3 and the stirring piece 72.
When the device works, the surfaces of the stirring blades 3 and the stirring sheets 72 are soft by attaching the soft films to the upper surfaces of the stirring blades 3 and the stirring sheets 72, so that the damage degree of the small-molecule collagen peptide can be reduced when the stirring blades 3 and the stirring sheets 72 are stirred; in addition, when the stirring blade 3 and the stirring sheet 72 are cleaned, the soft film can be torn off and cleaned, so that the difficulty in cleaning the corners of the stirring blade 3 and the stirring sheet 72 is reduced; if the soft film is difficult to fix, the soft film is fixed by bonding with edible glue or by screws, and the soft film comprises an edible biological fiber film or an edible composite film made of polyester resin/polyethylene material.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. Any embodiment of the present disclosure may be deleted or modified as appropriate according to actual requirements, and the scope of the present disclosure is defined by the appended claims and their equivalents.
Claims (6)
1. The utility model provides a collagen peptide low temperature enzymolysis system, includes the enzymolysis container, its characterized in that: the enzymolysis container comprises a columnar container (1), a heating ball (2) positioned at the rotation center of the columnar container (1) and a mounting rack (21); the heating ball (2) is sleeved with a graphene layer (22); a first spherical shell (23) is sleeved outside the graphene layer (22), and the inner wall of the first spherical shell (23) is not in contact with the outer wall of the graphene layer (22); a first pipe (24) is arranged at the upper end of the first spherical shell (23), an installation frame (21) is arranged on the side part of the columnar container (1), and the installation frame (21) is in an inverted L shape; one end of the mounting frame (21) is fixedly connected with the side part of the columnar container (1), the other end of the mounting frame (21) extends to the top end of the first pipe (24), and the first pipe (24) is fixed with the side part of the columnar container (1) through the mounting frame (21); a second spherical shell (25) is further sleeved outside the first spherical shell (23), and the inner wall of the second spherical shell (25) is not in contact with the outer wall of the first spherical shell (23); the upper end of the second spherical shell (25) is connected with a second pipe (26); the first tube (24) is positioned inside the second tube (26), and the first tube and the second tube are not contacted with each other; the second pipe (26) extends out of the upper end of the columnar container (1), and a gear ring (27) is fixedly arranged on the second pipe (26) positioned outside the columnar container (1); the second pipe (26) is rotationally connected with the columnar container (1); a motor (28) is arranged on the side surface of the columnar container (1); the motor (28) drives the gear ring (27) to rotate through a gear belt; a plurality of stirring blades (3) are uniformly distributed on the outer surface of the second spherical shell (25), and the stirring blades (3) are positioned on the same horizontal plane; a first water pipe (4) is arranged between the first pipe (24) and the second pipe (26); the first water pipe (4) comprises a first static pipe (41), a first moving pipe (42) and a fluid slip ring (5); the fluid slip ring (5) comprises an upper annular cover (51) and a lower annular shell (52) capable of rotating in a sealing mode relative to the upper annular cover (51), and the upper annular cover (51) and the lower annular shell (52) enclose to form a first cavity (53); the first static pipe (41) penetrates through the upper annular cover (51) and is communicated with the first cavity (53); the first number of moving pipes (42) penetrate through the lower annular shell (52) and are communicated with the first number of cavities (53); the side wall of the lower annular shell (52) is fixedly connected with the inner wall of the second tube (26);
the upper annular cover (51) is fixedly connected with the outer wall of the first pipe (24) through a bracket (54); one end of the first moving pipe (42) is communicated with the first cavity (53), the other end of the first moving pipe penetrates through a gap between the first spherical shell (23) and the second spherical shell (25) and is wound at the gap, the first moving pipe (42) is wound and then sequentially penetrates into each stirring blade (3), penetrates out of the gap between the first pipe (24) and the second pipe (26), and is communicated with the first cavity (53) again; the first spherical shell (23), the second spherical shell (25), the stirring blade (3) and the first water pipe (4) are all made of transparent materials; the upper end of the columnar container (1) is provided with a raw material inlet (11), and the side wall of the lower end of the columnar container (1) is provided with a material outlet (12).
2. The low-temperature enzymolysis system for collagen peptide according to claim 1, wherein: a second water pipe (6) is arranged between the first pipe (24) and the second pipe (26); the second water pipe (6) and the first water pipe (4) are arranged in parallel and are fixedly connected with each other; a second cavity (61) concentric with the first cavity (53) is further isolated in the fluid slip ring (5), the inner diameter of the first cavity (53) is larger than the outer diameter of the second cavity (61), and the second water pipe (6) comprises a second static pipe and a second moving pipe; the second static pipe penetrates through the upper annular cover (51) and is communicated with the second cavity (61); the second moving pipe penetrates through the lower annular shell (52) and is communicated with the second cavity (61); a first water pipe (4) in the stirring blade (3) is attached to a second water pipe (6); the second water pipe (6) is made of transparent material; the flow direction of the cooling liquid in the first water pipe (4) is opposite to that of the cooling liquid in the second water pipe (6).
3. The low-temperature enzymolysis system for collagen peptide according to claim 2, wherein: the first water pipe (4) and the second water pipe (6) in the gap between the first spherical shell (23) and the second spherical shell (25) are arranged in parallel in a contact manner, the contact surface of the first water pipe (4) and the second water pipe (6) which are in parallel contact penetrates through the lower part of the rotation center of the second water pipe (26), and the first water pipe (4) and the second water pipe (6) which are positioned below the rotation center of the second water pipe (26) are communicated; a first rotating shaft (7) is arranged at the communication position of the first water pipe (4) and the second water pipe (6); the one end equipartition of a pivot (7) has drive blade (71), and the other end equipartition of a pivot (7) has a plurality of stirring pieces (72), drive blade (71) are located the central authorities of a water pipe (4) and No. two water pipe (6) intercommunication departments.
4. The low-temperature enzymolysis system for collagen peptide according to claim 3, wherein: the stirring blade (72) is sleeved with a barrel-shaped shell (73), the shell (73) is fixedly connected with the second spherical shell (25), the stirring blade (72) is spiral, a plurality of conveying pipes (74) are uniformly arranged at the top of the shell (73), one ends of the conveying pipes (74) are communicated with the inside of the barrel-shaped shell (73), and the other ends of the conveying pipes (74) are located at the top end of the second spherical shell (25).
5. The system according to claim 2, 3 or 4, wherein the collagen peptide low temperature enzymolysis system comprises: the stirring blade (3) is provided with a turbulent flow pipe (75); the turbulent flow pipe (75) is arranged along the length direction of the stirring blade (3), one end of the turbulent flow pipe (75) is positioned at the edge of the stirring blade (3), and the pipe orifice of the turbulent flow pipe (75) faces to the rotation direction tangential to the stirring blade (3); the other end of the turbulent flow pipe (75) points to the stirring sheet (72) along the surface of the second spherical shell (25).
6. The low-temperature enzymolysis system for collagen peptide according to claim 2, wherein: and soft films are attached to the surfaces of the stirring blades (3) and the stirring sheets (72).
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| CN202111191798.9A CN113832026A (en) | 2021-10-13 | 2021-10-13 | Collagen peptide low temperature enzymolysis system |
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