CN113827638A - 一种鼻炎药油及其制备方法 - Google Patents
一种鼻炎药油及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种鼻炎药油及制备方法,重量份数的原料制备而成:黄芩52‑70份、辛夷16‑24份、防风15‑25份、荊芥14‑23份、白术18‑24份、柴胡17‑23份、金银花36‑42份、大黄15‑22份、白芷18‑22份、川穹19‑25份、苍耳子26‑33份、鹅不食草17‑21份。本发明鼻炎药油通过多种组分相互配合,协同促进,使治疗鼻炎的效果显著,治愈率高,不复发。
Description
技术领域
本发明涉及一种中药,尤其指一种鼻炎药及制备方法。
背景技术
鼻炎即鼻腔炎性疾病,是病毒、细菌、变应原、各种理化因子以及某些全身性疾病引起的鼻腔黏膜的炎症。鼻炎的主要病理改变是鼻腔黏膜充血、肿胀、渗出、增生、萎缩或坏死等。鼻炎病因包括:病毒感染、鼻黏膜易感性等,病毒感染是其首要病因,或在病毒感染的基础上继发细菌感染,已知有100多种病毒可引起本病,最常见的是鼻病毒,其次是流感和副流感病毒、腺病毒、冠状病毒、柯萨奇病毒及黏液和副黏液病毒等,病毒传播方式主要是经过呼吸道吸入,其次是通过被污染体或食物进入机体,易感性的产生源于抗原物质的经常刺激,但其易感程度则视鼻黏膜组织中肥大细胞、嗜碱性粒细胞的数量和释放化学介质的能力,变应性鼻炎患者鼻黏膜中上述细胞数量不仅高于正常人,且有较强释放化学介质的能力,患者可以将一些鼻炎治疗药物敷在鼻子内部,可以暂时对鼻炎起到一定的治疗作用。
目前,治疗鼻炎、鼻窦炎、额窦炎以及鼻息肉、鼻甲肥大等疾病的药物很多,但是,大都存在效果不够明显,治愈率较低,而且治疗时间长、治疗费用高、而且会反复复发等缺陷。
发明内容
本发明要解决的技术问题是克服以上技术问题,提供一种疗效好、药效稳定、复发率低、使用方便的鼻炎药油及制备方法。
一种鼻炎药油,包括下列重量份数的原料制备而成:黄芩52-70份、辛夷16-24份、防风15-25份、荊芥14-23份、白术18-24份、柴胡17-23份、金银花36-42份、大黄15-22份、白芷18-22份、川穹19-25份、苍耳子26-33份、鹅不食草17-21份。
优选地,包括下列重量份数的原料制备而成:黄芩60份、辛夷20份、防风20份、荊芥20份、白术20份、柴胡20份、金银花40份、大黄20份、白芷20份、川穹20份、苍耳子30份、鹅不食草20份。
本发明的另一个目的是提供一种鼻炎药油的制备方法,步骤如下:
(1)、按照重量组分分别称量各原料,经过筛选、去除杂质后,放入容器内混合;
(2)、取豆油放到步骤(1)所述的容器中,使各原料在豆油中浸泡36小时,然后按照黑豆馏油的办法,等到了时间。
(3)、对步骤(2)中浸有中药的豆油使用文火煎熬,煎熬60分钟;
(4)、待步骤(3)在豆油中煎熬的中药即将出现黑化现象时,立即停火,并对其进行过滤,过滤掉煎熬后的混合中药渣,获得药油;
(5)、将步骤(4)中所得药油静置冷却,装入清洁瓶内密封,即得鼻炎药油。
上述一种鼻炎药油的制备方法,优选的方案是,所述步骤(2)中原料药:豆油按照1:120的重量比混合浸泡。
上述一种鼻炎药油的制备方法,优选的方案是,所述步骤(3)中文火温度为70℃。
本发明具有如下有益效果:
黄芩补肺气,益卫气,辛夷化湿通鼻窍,为治疗鼻渊要药;防风、荊芥祛风解表,白术健脾益气配伍柴胡、金银花、大黄、白芷、川穹、苍耳子、鹅不食草共同起到清热解毒通窍止痛的功效;可以快速控制致敏原、清理鼻腔内的致病菌和垃圾,可以有效的避免过敏源,冷空气和病菌的刺激,提高鼻炎患者的机体免疫能力,适用于各种急慢性鼻炎、鼻窦炎、过敏性鼻炎;可外用鼻炎药油,治愈率高,不易复发。
具体实施方式
实施例1一种鼻炎药油的制备方法,包括如下步骤:
(1)、按照重量组分准备:黄芩52份、辛夷16份、防风15份、荊芥14份、白术18份、柴胡17份、金银花36份、大黄15份、白芷18份、川穹19份、苍耳子26份、鹅不食草17份,经过筛选、去除杂质后,放入容器内混合;
(2)、取豆油放到步骤(1)所述的容器中,使各原料在豆油中浸泡36小时,其中原料药与豆油的重量比为1:120;
(3)、对步骤(2)中浸有中药的豆油使用文火煎熬,文火温度为70℃,煎熬60分钟;
(4)、待步骤(3)在豆油中煎熬的中药即将出现黑化现象时,立即停火,并对其进行过滤,过滤掉煎熬后的混合中药渣,获得药油;
(5)、将步骤(4)中所得药油静置冷却,装入清洁瓶内密封,即得鼻炎药油。
该鼻炎药油的使用方法:用棉球均匀蘸涂药油一半,塞入鼻腔,棉球导入药油。可根据病情分上、中、下鼻道导入鼻孔2—2.5cm。治疗以早中晚每天3-4次,晚上睡觉前1—2个小时效果最佳。每日3—4次,每次15—30分钟或棉球自动掉出,儿童在三十分钟以上即可。病症严重者,可根据需要白天适量涂抹本药或者塞中药油。棉球的大小以不影响正常呼吸为准,2个月为一个疗程。
实施例2一种鼻炎药油的制备方法,包括如下步骤:
(1)、按照重量组分准备:黄芩70份、辛夷24份、防风25份、荊芥23份、白术24份、柴胡23份、金银花42份、大黄22份、白芷22份、川穹25份、苍耳子33份、鹅不食草21份,经过筛选、去除杂质后,放入容器内混合;
(2)、取豆油放到步骤(1)所述的容器中,使各原料在豆油中浸泡36小时,其中原料药与豆油的重量比为1:120;
(3)、对步骤(2)中浸有中药的豆油使用文火煎熬,文火温度为70℃,煎熬60分钟;
(4)、待步骤(3)在豆油中煎熬的中药即将出现黑化现象时,立即停火,并对其进行过滤,过滤掉煎熬后的混合中药渣,获得药油;
(5)、将步骤(4)中所得药油静置冷却,装入清洁瓶内密封,即得鼻炎药油。
该鼻炎药油的使用方法:用棉球均匀蘸涂药油一半,塞入鼻腔,棉球导入药油。可根据病情分上、中、下鼻道导入鼻孔2—2.5cm。治疗以早中晚每天3-4次,晚上睡觉前1—2个小时效果最佳。每日3—4次,每次15—30分钟或棉球自动掉出,儿童在三十分钟以上即可。病症严重者,可根据需要白天适量涂抹本药或者塞中药油。棉球的大小以不影响正常呼吸为准,2个月为一个疗程。
实施例3一种鼻炎药油的制备方法,包括如下步骤:
(1)、按照重量组分准备:黄芩60份、辛夷20份、防风20份、荊芥20份、白术20份、柴胡20份、金银花40份、大黄20份、白芷20份、川穹20份、苍耳子30份、鹅不食草20份,经过筛选、去除杂质后,放入容器内混合;
(2)、取豆油放到步骤(1)所述的容器中,使各原料在豆油中浸泡36小时,其中原料药与豆油的重量比为1:120;
(3)、对步骤(2)中浸有中药的豆油使用文火煎熬,文火温度为70℃,煎熬60分钟;
(4)、待步骤(3)在豆油中煎熬的中药即将出现黑化现象时,立即停火,并对其进行过滤,过滤掉煎熬后的混合中药渣,获得药油;
(5)、将步骤(4)中所得药油静置冷却,装入清洁瓶内密封,即得鼻炎药油。
该鼻炎药油的使用方法:用棉球均匀蘸涂药油一半,塞入鼻腔,棉球导入药油。可根据病情分上、中、下鼻道导入鼻孔2—2.5cm。治疗以早中晚每天3-4次,晚上睡觉前1—2个小时效果最佳。每日3—4次,每次15—30分钟或棉球自动掉出,儿童在三十分钟以上即可。病症严重者,可根据需要白天适量涂抹本药或者塞中药油。棉球的大小以不影响正常呼吸为准,2个月为一个疗程。
临床研究:
1、皮肤刺激试验:选择10毫升药油大白兔三只,将背部兔毛全部剃干净。用本发明实施例3所得鼻炎油每天涂搓大白兔背部4次,每两小时观察一次,是否有红、肿、热、水疱、渗出、结痂、眼睑红肿等症状。
共观察外用涂搓30天,三只大白兔背部均无皮肤刺激症状,无红、肿、热、小疱、渗出、结痂现象。证明中药外用油剂无刺激,无副作用。
2、人体治疗试验:
(1)选择急慢性鼻炎和过敏性鼻炎、鼻窦炎、筛窦炎、副鼻窦炎、泪囊炎、上额窦炎等各种鼻炎患者,临床症状有打喷嚏、流鼻涕、鼻塞、臭觉减退、鼻痒、干、出血、个别伴头痛头晕眼睛干痒迎风流泪、中耳炎的等病人为治疗对象。
(2)具体分组情况:
治疗组:病例选择1岁-60岁男女565例,男性310例,女性255例,采用本发明实施例3所得鼻炎药油,治疗观察三个月为限制。
对照组:选择过敏性鼻炎1-60岁男女550例,男性300例,女性250例。治疗外用滴鼻净、抗过敏药物,如扑尔敏、进口药物等。
(3)疗效判定标准:
治愈:病人临床症状消失,无打喷嚏、流鼻涕、鼻塞、鼻痒、嗅觉减退或消失,伴有头痛、头晕病人。症状全部消失。
显效:病人无打喷嚏、流鼻涕、鼻痒、鼻塞患者,仍有嗅觉减退或消失,自觉有头痛不适等症状。
有效:病人打喷嚏、流鼻涕减轻,鼻塞、鼻痒、眼睛中耳炎等症状均减轻。
无效:以临床症状均无明显改善。
(4)治疗结果:
治疗组:
治愈:543例,治愈率96.1%,
显效:11例,显效率1.9%,
有效:5例,有效率1%,
无效:6例,无效率1%,
总有效率(治愈率+显效率+有效率)为99%。
对照组:
治愈:456例,治愈率83%。
显效:28例,显效率5%。
有效:38例,有效率7%。
无效:128例,无效率5%。
总有效率为95%。
两组治疗效果对照差异较大。
结果显示:本发明鼻炎油治疗急慢性鼻炎和过敏性鼻炎、鼻窦炎、筛窦炎、副鼻窦炎、泪囊炎、上额窦炎等各种鼻炎患者,临床症状有打喷嚏、流鼻涕、鼻塞、臭觉减退、鼻痒、干、出血、个别伴头痛头晕眼睛干痒迎风流泪、中耳炎均有显著治疗效果。观察一年内无复发效果。治疗过程中发现,患病时间越短,治疗效果越明显,而且一年内无复发。该鼻炎药治疗过敏性鼻炎不但效果显著,而且有不复发功效,起到预防和治疗作用。
以上所述仅是本发明的优选实施方式,应当指出,对于本技术领域的普通技术人员来说,在不脱离本发明技术原理的前提下,还可以做出若干改进,这些改进也应视为本发明的保护范围。
Claims (5)
1.一种鼻炎药油,其特征在于,包括下列重量份数的原料制备而成:黄芩52-70份、辛夷16-24份、防风15-25份、荊芥14-23份、白术18-24份、柴胡17-23份、金银花36-42份、大黄15-22份、白芷18-22份、川穹19-25份、苍耳子26-33份、鹅不食草17-21份。
2.根据权利要求1所述的一种鼻炎药油,其特征在于,包括下列重量份数的原料制备而成:黄芩60份、辛夷20份、防风20份、荊芥20份、白术20份、柴胡20份、金银花40份、大黄20份、白芷20份、川穹20份、苍耳子30份、鹅不食草20份。
3.一种如权利要求1-2任一所述的鼻炎药油的制备方法,其特征在于,步骤如下:
(1)、按照重量组分分别称量各原料,经过筛选、去除杂质后,放入容器内混合;
(2)、取豆油放到步骤(1)所述的容器中,使各原料在豆油中浸泡36小时,然后按照黑豆馏油的办法,等到了时间。
(3)、对步骤(2)中浸有中药的豆油使用文火煎熬,煎熬60分钟;
(4)、待步骤(3)在豆油中煎熬的中药即将出现黑化现象时,立即停火,并对其进行过滤,过滤掉煎熬后的混合中药渣,获得药油;
(5)、将步骤(4)中所得药油静置冷却,装入清洁瓶内密封,即得鼻炎药油。
4.根据权利要求3所述的一种鼻炎药油的制备方法,其特征在于:所述步骤(2)中原料药:豆油按照1:120的重量比混合浸泡。
5.根据权利要求3所述的一种鼻炎药油的制备方法,其特征在于:所述步骤(3)中文火温度为70℃。
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