CN113816955A - RET kinase inhibitor intermediate and preparation method thereof - Google Patents
RET kinase inhibitor intermediate and preparation method thereof Download PDFInfo
- Publication number
- CN113816955A CN113816955A CN202111147388.4A CN202111147388A CN113816955A CN 113816955 A CN113816955 A CN 113816955A CN 202111147388 A CN202111147388 A CN 202111147388A CN 113816955 A CN113816955 A CN 113816955A
- Authority
- CN
- China
- Prior art keywords
- compound
- reaction
- preparation
- diazabicyclo
- kinase inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111147388.4A CN113816955B (en) | 2021-09-29 | 2021-09-29 | RET kinase inhibitor intermediate and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111147388.4A CN113816955B (en) | 2021-09-29 | 2021-09-29 | RET kinase inhibitor intermediate and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN113816955A true CN113816955A (en) | 2021-12-21 |
CN113816955B CN113816955B (en) | 2022-08-26 |
Family
ID=78915818
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202111147388.4A Active CN113816955B (en) | 2021-09-29 | 2021-09-29 | RET kinase inhibitor intermediate and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN113816955B (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020200316A1 (en) * | 2019-04-03 | 2020-10-08 | 南京明德新药研发有限公司 | Pyrazolopyridine compound as ret inhibitor and application thereof |
-
2021
- 2021-09-29 CN CN202111147388.4A patent/CN113816955B/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020200316A1 (en) * | 2019-04-03 | 2020-10-08 | 南京明德新药研发有限公司 | Pyrazolopyridine compound as ret inhibitor and application thereof |
Also Published As
Publication number | Publication date |
---|---|
CN113816955B (en) | 2022-08-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2903797C (en) | Processes for the preparation of an apoptosis-inducing agent | |
JP7365349B2 (en) | Method for producing prostaglandin analogs that donate nitric oxide | |
KR102396059B1 (en) | Novel compound and method for preparing same | |
CA2351528C (en) | Process for the preparation of a piperazine derivative | |
CN115417816B (en) | Preparation method of 3, 6-dibromo-1-chloro-isoquinoline | |
CN113816955B (en) | RET kinase inhibitor intermediate and preparation method thereof | |
EP2483246B1 (en) | Process for preparing biphenyl imidazole compounds | |
CN113336703B (en) | Synthesis of 1,3,4, 5-tetrasubstituted 1H-pyrazole derivatives | |
US6562975B1 (en) | Process for preparing zolpidem | |
EP3911660B1 (en) | Process for preparation of 2-amino-5-hydroxy propiophenone | |
CA2445766A1 (en) | Improved process for preparing zolpidem | |
KR101557702B1 (en) | Method for the preparation of Mitiglinide Calcium Dihydrate | |
CN113372281A (en) | Synthetic method of metronidazole | |
WO2016115962A1 (en) | Preparation method for nebivolol intermediate and preparation method for nebivolol | |
KR100856133B1 (en) | Improved process for preparing atorvastatin | |
KR101529963B1 (en) | Method for preparing everolimus and its intermediates | |
CN113549070B (en) | Preparation method of malavisuo and derivatives thereof | |
KR100448640B1 (en) | Method for producing phenyl propionic acid derivatives with high yield and purity | |
KR100759640B1 (en) | Process for producing penicillanic acid compound | |
JP2022529000A (en) | Method for Producing Substituted 2- [2- (Phenyl) Ethylamino] Alkaneamide Derivative | |
KR100388108B1 (en) | New process for producing intermediates of cephalosporin antibiotics | |
JP2023503647A (en) | Process for the preparation of novel crystalline forms of 1-(4-benzyloxy-benzyl)-3-methyl-thiourea | |
KR20230027521A (en) | Method for producing high-purity everolimus using a metal catalyst, an acid catalyst, and a phase transfer catalyst | |
KR100566896B1 (en) | Processes for the preparation of an optically active 5,6-dioxopiperazine-2-carboxylic acid derivative | |
JP2685896B2 (en) | Cyclopenta [d] pyrimidine derivative and process for producing the same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Luo Shanmei Inventor after: Ye Zhaobao Inventor after: Chen Zhijun Inventor after: Wang Huangwei Inventor after: Chen Jiahui Inventor after: Zeng Yuandong Inventor after: Yang Hua Inventor before: Luo Shange Inventor before: Ye Zhaobao Inventor before: Chen Zhijun Inventor before: Wang Huangwei Inventor before: Chen Jiahui Inventor before: Zeng Yuandong Inventor before: Yang Hua |
|
CP01 | Change in the name or title of a patent holder | ||
CP01 | Change in the name or title of a patent holder |
Address after: 361101 room 402A, qiangye building, industrial zone, Xiamen Torch High tech Zone (Xiang'an), Xiamen, Fujian Patentee after: Xiamen Yunfan Biotechnology Co.,Ltd. Address before: 361101 room 402A, qiangye building, industrial zone, Xiamen Torch High tech Zone (Xiang'an), Xiamen, Fujian Patentee before: XIAMEN YUNFAN PHARMACEUTICAL Co.,Ltd. |