CN113796912A

CN113796912A - Intratumoral embolization device

Info

Publication number: CN113796912A
Application number: CN202111178110.3A
Authority: CN
Inventors: 王格; 刘斌
Original assignee: Shanghai Li Kai Technology Co ltd
Current assignee: Shanghai Li Kai Technology Co ltd
Priority date: 2021-10-09
Filing date: 2021-10-09
Publication date: 2021-12-17

Abstract

The application relates to an intratumoral embolization device, which comprises a connector and an extension tentacle; the connecting head is provided with a release structure for releasing in the tumor; the extension tentacle is metal or macromolecular material, and quantity is a plurality of, the extension tentacle is fixed extremely the surface of connector, not with release structure interferes with. Through the surface at the tie point be provided with a plurality of extensions tentacles, and extend and tentacle for metal or macromolecular material, the intratumoral embolism device of this application is similar to the sea anemone structure, after putting this embolism device into the aneurysm wholly, can form the thrombus in the aneurysm, the tumor body can atrophy gradually, reach the treatment purpose, adopt this structure to compare and fill into many pieces of spring coils, the operation is simpler, each aneurysm only needs once to pack just can obtain better treatment, and only once fill intratumoral embolism device reasonable the time of operation that has not only reduced, the operation risk is also littleer.

Description

Intratumoral embolization device

Technical Field

The application relates to the technical field of medical equipment, in particular to an intratumoral embolism device.

Background

The current primary treatment techniques for intracranial aneurysms are simple coil packing and stent/flow guide assisted coil packing, where the coil plays an important role in packing the aneurysm during treatment. After the aneurysm is filled, the aneurysm is not impacted by continuous blood flow any more, thrombus can be formed in the aneurysm, and the aneurysm body can be gradually shrunk, so that the aim of healing is fulfilled. One of the major problems with current metal coils is that a more desirable treatment effect can be achieved after multiple coils are inserted during a single operation, which prolongs the operation time and increases the risk of the operation.

Disclosure of Invention

In view of the above, the present application provides an intratumoral embolization device, which is characterized by comprising a connector and an extension tentacle; the outer surface of the connector is provided with a plurality of extending tentacles which extend outwards from the connector; the extension tentacle is soft material.

In a possible implementation manner, the extension tentacle is of a spring structure, and the extension tentacle is welded and fixed with the connector.

In a possible implementation manner, the extension tentacle is of a filiform structure, and the extension tentacle is fixedly bonded with the connector.

In one possible embodiment, the elongate tentacles are arranged uniformly on the connection head.

In a possible embodiment, the spring structure or the wire-like structure has at least one bend in the extension tentacle.

In a possible implementation manner, the connector is of a spherical structure, and the release structure is arranged on an outer wall of one side of the connector.

In a possible implementation manner, the connector is of an annular structure, and the extension tentacle is arranged on the annular side wall of the connector.

In one possible implementation, the number of the extension tentacles is within 50; the connector with the extension tentacle is the polymer material.

In one possible implementation, the length of each of the extended tentacles is in the range of 0-20 inches; the connector with the material of extending tentacle is degradable material.

In one possible implementation, the connector is further provided with a release structure, and the release structure can be detachably connected with the delivery guide wire.

The beneficial effect of this application: be provided with a plurality of extensions tentacles through the surface at the tie point, and extend and tentacle for soft materials, intratumoral embolism device of this application is similar to the sea anemone structure, medical personnel only need put this embolism device into aneurysm wholly, just can form the thrombus in the aneurysm, the tumor body can atrophy gradually, reach the treatment purpose, adopt this structure to compare and fill into many pieces of spring coils, the operation is simpler, each aneurysm only need once fill just can obtain better treatment, and only once fill intratumoral embolism device reasonable the time of operation that has not only reduced in the tumour, the operation risk is also littleer. The embolism device filled in the tumor not only reasonably reduces the operation time, but also has smaller operation risk.

Other features and aspects of the present application will become apparent from the following detailed description of exemplary embodiments, which proceeds with reference to the accompanying drawings.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate exemplary embodiments, features, and aspects of the application and, together with the description, serve to explain the principles of the application.

Fig. 1 shows a perspective view of an intratumoral plug structure according to an embodiment of the present application;

fig. 2 shows a perspective view of an intratumoral plug structure according to another embodiment of the present application.

Detailed Description

Various exemplary embodiments, features and aspects of the present application will be described in detail below with reference to the accompanying drawings. In the drawings, like reference numbers can indicate functionally identical or similar elements. While the various aspects of the embodiments are presented in drawings, the drawings are not necessarily drawn to scale unless specifically indicated.

It will be understood, however, that the terms "central," "longitudinal," "lateral," "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in an orientation or positional relationship indicated in the drawings for convenience in describing the present application or for simplicity of description, and do not indicate or imply that the device or element so referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be considered limiting of the present application.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present application, "a plurality" means two or more unless specifically limited otherwise.

The word "exemplary" is used exclusively herein to mean "serving as an example, embodiment, or illustration. Any embodiment described herein as "exemplary" is not necessarily to be construed as preferred or advantageous over other embodiments.

Furthermore, in the following detailed description, numerous specific details are set forth in order to provide a better understanding of the present application. It will be understood by those skilled in the art that the present application may be practiced without some of these specific details. In some instances, methods, means, elements and circuits that are well known to those skilled in the art have not been described in detail so as not to obscure the present application.

Fig. 1 shows a perspective view of an intratumoral plug structure according to an embodiment of the present application; fig. 2 shows a perspective view of an intratumoral plug structure according to another embodiment of the present application.

As shown in fig. 1-2, the intratumoral embolization device comprises a connector 20 and an extension tentacle 10; a plurality of extending tentacles 10 are arranged on the outer surface of the connector 20, and the extending tentacles 10 extend outwards from the connector 20; the extension tentacle 10 is made of soft material; the connector 20 is further provided with a release structure 21, and the release structure 21 can be detachably connected with the delivery guide wire.

In this embodiment, through being provided with a plurality of extensions tentacles 10 at the surface of tie point, and extension tentacles 10 is soft materials, the intratumoral embolism device of this application is similar to the sea anemone structure, medical personnel only need put this embolism device into aneurysm wholly, just can form the thrombus in the aneurysm, the tumor body can atrophy gradually, reach the treatment purpose, adopt this structure to compare and fill into the spring coil many times, it is simpler to operate, each aneurysm only need once fill just can obtain better treatment, and only once fill intratumoral embolism device not only the reasonable time of shortening the operation, the risk of operation is also littleer.

The specific work flow of the intratumoral embolization device of the present application is: the connecting point is connected with the conveying guide wire, medical personnel operate the conveying guide wire to convey the intratumoral embolism device to the far end until the intratumoral embolism device is placed into an aneurysm, the aneurysm is plugged, continuous blood flow impact is avoided, thrombus can be formed in the aneurysm, the intratumoral embolism device and the conveying guide wire are released, and the intratumoral embolism device is left in the aneurysm to achieve the purpose of treatment.

Here, the detachment may be mechanical detachment or electrical detachment, in which the proximal end of the delivery rod is connected to an electrode through electrolysis, and the junction between the implanted intratumoral embolization device of the present application and the delivery rod is electrified and the junction is dissolved through electrochemical reaction, thereby achieving the purpose of detachment. The releasing mode is the prior art in the field, and no change is made in the scheme, so the details are not described herein.

In one embodiment, as shown in fig. 1, the extension tentacle 10 is a spring structure, and the extension tentacle 10 is welded to the connector 20.

In this embodiment, it should be pointed out specifically that, according to the material difference of extension tentacle 10, the physical property is different, and extension tentacle and connector 20 can select different connected mode for it is more firm, the stronger connection two of adaptation, and a plurality of extension tentacles 10 of multi-angle outside fixed on connector 20, except playing the function of packing, can also the auxiliary stay whole embolism device, do benefit to the formation of thrombus in the tumour.

More specifically, the extension tentacle 10 may be of a spring structure, and the extension tentacle 10 of the spring structure is usually made of a metal material, such as gold, platinum iridium, platinum tungsten, platinum nickel alloy, etc., and is fixed to the connector 20 by a welding fixing method.

In one embodiment, as shown in fig. 2, the extension tentacle 10 is a thread-like structure, and the extension tentacle 10 is adhesively fixed to the connector 20.

In this embodiment, the extension tentacles 10 are wire-like structures, and the wire-like structures of the extension tentacles 10 are usually fixed to the connecting head 20 by an adhesive fixing method.

It should be noted that the length of the elongate tentacle 10 is not limited in any way in the above embodiments, and that the elongate tentacle 10 may be sized appropriately to deliver the intratumoral embolic device into the aneurysm.

In one embodiment, the extended tentacles 10 are evenly distributed on the connection head 20.

In this embodiment, the extension tentacles 10 are uniformly arranged on the outer surface of the connector 20, and the extension heads are uniformly distributed on the connector 20.

In one embodiment, the spring structure extends to form at least one bend in the tentacle 10.

In this embodiment, the extension tentacle 10 with the spring structure is molded to have at least one bending structure, so that the extension tentacle 10 with the bending structure can be more easily attached to the inside of the aneurysm, the aneurysm can be more efficiently embolized, and the extension tentacle 10 with the bending structure has better support strength.

Preferably, the spring-structured extension tentacle 10 is "S" shaped, that is, the spring-structured extension tentacle 10 has two bending structures.

In one embodiment, the connection head 20 has a ball-shaped structure, and the release structure 21 is disposed on an outer wall of one side of the connection head 20.

In one embodiment, the connector is a ring structure, and the extension tentacle 10 is disposed on the annular sidewall of the connector 20.

In one embodiment, the number of tentacles 10 is extended to within 50.

In this embodiment, it is preferable that the number of the extension tentacles 10 on the outer surface of the connecting head 20 is less than 50, and it should be noted that, in general, the number of the extension tentacles 10 having the spring structure or the wire structure is less, and the number of the extension tentacles 10 having the wire structure is more.

In one embodiment, each of the extended tentacles 10 has a length in the range of 5-20 inches.

In this embodiment, in general, the wire diameter or the spring diameter of the extension tentacle 10 is inversely proportional to the length of the extension tentacle, and practitioners in the art can determine how many specifications of extension tentacles to use by themselves according to specific situations, and only need to ensure that the intratumoral embolization device can be smoothly and simply placed into an aneurysm and effectively embolize the aneurysm, so that specifications and sizes of the specific extension tentacle do not need to be more specifically limited.

In one embodiment, the connector 20 and the extension tentacle 10 are made of degradable material.

In this embodiment, the material of the connector 20 and the extension tentacle 10 may be LGA, iron-based degradable alloy, magnesium-based degradable alloy, etc., which can be absorbed or discharged by human body, and after the therapeutic effect is achieved, the connector is not required to be manually taken out, which is simple and fast. The device release mode can be electrolytic release or mechanical release.

In one embodiment, the releasing structure 21 is a column structure, and is connected to the connecting head 20 smoothly.

In one embodiment, the connector 20 and the extension tentacle 10 are made of polymer.

In this embodiment, the material of the connector 20 and the extension tentacle 10 may be PP, PE, PET, etc.

Having described embodiments of the present application, the foregoing description is intended to be exemplary, not exhaustive, and not limited to the disclosed embodiments. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments. The terminology used herein is chosen in order to best explain the principles of the embodiments, the practical application, or improvements made to the technology in the marketplace, or to enable others of ordinary skill in the art to understand the embodiments disclosed herein.

Claims

1. An intratumoral embolization device is characterized by comprising a connector and an extension tentacle;

the outer surface of the connector is provided with a plurality of extending tentacles which extend outwards from the connector; the extension tentacle is made of metal or high polymer materials.

2. The intratumoral embolization device according to claim 1, wherein the extension tentacle is of a spring construction, and the extension tentacle is fixed to the connector by means of gluing, welding or nesting.

3. The intratumoral embolization device according to claim 1, wherein the extension tentacle is a filiform structure, said extension tentacle being fixed to said connector by means of gluing, welding or nesting.

4. An intratumoral embolization device according to claim 1, wherein the extension tentacles are arranged on the connecting head, overall in a sea anemone configuration.

5. An intratumoral embolization device according to claim 2, wherein said extension of the spring structure or wire-like structure comprises at least one bend.

6. An intratumoral embolization device according to any one of claims 1 to 5, wherein the connecting head is of a bulbous configuration, the disengaging structure being provided on one side of the outer wall of the connecting head.

7. An intratumoral embolization device according to any one of claims 1 to 5, wherein the connecting head is of annular configuration, the extension tentacles being provided on the annular side wall of the connecting head.

8. An intratumoral embolization device according to claim 6, wherein the number of extending tentacles is within 50;

the connector with extend tentacle and be metal or polymer material.

9. An intratumoral embolization device according to claim 6, wherein each of the extending tentacles has a length in the range of 0-20 inches.

10. An intratumoral embolization device according to claim 6, wherein said connecting head is further provided with a detachment structure which is releasably connectable to a delivery guidewire.