CN113740127A - Non-contact refrigeration type ultrasonic pulverizer - Google Patents

Non-contact refrigeration type ultrasonic pulverizer Download PDF

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Publication number
CN113740127A
CN113740127A CN202110906300.6A CN202110906300A CN113740127A CN 113740127 A CN113740127 A CN 113740127A CN 202110906300 A CN202110906300 A CN 202110906300A CN 113740127 A CN113740127 A CN 113740127A
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CN
China
Prior art keywords
amplitude transformer
ring
ultrasonic
box body
double
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Pending
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CN202110906300.6A
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Chinese (zh)
Inventor
周芳
肖长锦
陈华
王仁华
黎池元
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Ningbo Scientz Biotechnology Co ltd
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Ningbo Scientz Biotechnology Co ltd
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Priority to CN202110906300.6A priority Critical patent/CN113740127A/en
Publication of CN113740127A publication Critical patent/CN113740127A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Crushing And Pulverization Processes (AREA)
  • Crushing And Grinding (AREA)

Abstract

The invention discloses a non-contact refrigeration type ultrasonic pulverizer which comprises a box body, an amplitude transformer, an energy converter and a rotating motor, wherein the rotating motor is arranged on the upper side of the box body, the output end of the rotating motor vertically extends into the box body and is connected with a centrifugal tube adapter, one or more hole sites for installing a centrifugal tube are arranged on the centrifugal tube adapter, the energy converter is vertically fixed at the lower end of the amplitude transformer, the upper end of the amplitude transformer vertically extends into the box body, the upper end of the amplitude transformer is positioned below the centrifugal tube adapter, ultrasonic medium liquid is arranged in the box body, a liquid discharge port is formed in the bottom of the box body, and circulating cooling water is arranged on the periphery of the box body. The ultrasonic crusher can avoid the pollution of samples and effectively solve the problem that the ultrasonic cavitation effect is influenced by unnecessary ultrasonic conduction of flowing circulating cooling water, in addition, the ultrasonic crusher can realize zero loss of energy conduction, can simultaneously carry out non-contact treatment on one or more samples, and has good treatment consistency.

Description

Non-contact refrigeration type ultrasonic pulverizer
Technical Field
The invention relates to an ultrasonic crusher, in particular to a non-contact refrigeration type ultrasonic crusher.
Background
An ultrasonic crusher is an analytical instrument which is widely applied to the fields of biology, materials, medicines, chemical engineering and the like. The ultrasonic crusher utilizes the action of ultrasonic aggregation energy to enable liquid to generate a cavitation effect, and cell substances and materials can be crushed, cracked and extracted under the action of the cavitation effect, so that researchers can extract useful components to conduct relevant research. The existing ultrasonic crusher is in a contact type, an amplitude transformer (namely a probe) of the existing ultrasonic crusher needs to extend into a centrifugal tube filled with a sample to be contacted with the sample, the amplitude transformer is made of a metal material, and in the process of contacting with the sample, metal elements on the surface of the amplitude transformer are possibly dissolved into the sample to pollute the sample; moreover, an operator needs to visually observe whether the amplitude transformer rod extends in place in the centrifugal tube and correspondingly adjust the amplitude transformer rod, so that the operation is complicated. In addition, most of the existing ultrasonic crushers adopt a horn, only a single sample can be detected each time, and the efficiency is low. Some ultrasonic crushers adopt a plurality of amplitude transformer to process a plurality of samples at the same time, but the action consistency of a plurality of probes is difficult to guarantee, and the accuracy of the experimental result is influenced.
Disclosure of Invention
The technical problem to be solved by the invention is to provide a non-contact refrigeration type ultrasonic crusher aiming at the defects of the prior art, which can avoid the pollution of samples and effectively solve the problem that the ultrasonic cavitation effect is influenced by unnecessary ultrasonic conduction of flowing circulating cooling water.
The technical scheme adopted by the invention for solving the technical problems is as follows: the utility model provides a non-contact refrigeration formula ultrasonic pulverizer, includes box, becomes width of cloth pole, transducer and rotating electrical machines, the rotating electrical machines install the upside of box, the vertical income of output of rotating electrical machines the box in link to each other with a centrifuging tube adapter, the centrifuging tube adapter on be equipped with one or more hole sites that are used for installing the centrifuging tube, the transducer vertical fix become the lower extreme of width of cloth pole, the upper end of width of cloth pole vertical stretch into the box in, the upper end of width of cloth pole be located the below of centrifuging tube adapter, the box in installed ultrasonic medium liquid, the bottom of box be provided with the leakage fluid dram, the periphery of box be provided with recirculated cooling water.
The refrigeration type ultrasonic crusher is a non-contact type ultrasonic crusher, and when a sample is subjected to ultrasonic crushing, the amplitude transformer of the refrigeration type ultrasonic crusher is not contacted with the sample, so that the sample can be prevented from being polluted. The non-contact refrigeration type ultrasonic crusher separates the circulating cooling water from the ultrasonic medium liquid, namely the circulating cooling water is arranged on the periphery of the box body to cool the box body, and the ultrasonic medium liquid is arranged in the box body for ultrasonic conduction, so that the problem that the ultrasonic cavitation effect is influenced by unnecessary ultrasonic conduction of the flowing circulating cooling water can be effectively solved. The temperature control range of the non-contact refrigeration type ultrasonic crusher can be designed to be-10 ℃ to room temperature. In addition, the non-contact refrigeration type ultrasonic crusher has large power selection range of the amplitude transformer, the high-power amplitude transformer can be used as a wave generation source, the upper end surface of the amplitude transformer is a wave generation surface, glue required by the traditional wave generation is not required to be coated on the surface of the wave generation surface, and zero loss of energy conduction can be realized.
The non-contact refrigeration type ultrasonic crusher can simultaneously process one or more samples under the condition that the amplitude transformer is fixed. The centrifugal tube with the sample is mounted on the centrifugal tube adapter, and after the ultrasonic medium liquid is filled in the box body, the sample can be processed in a non-contact mode, and the processing consistency is good. In the experimental process, the ultrasonic medium liquid and the centrifugal tube in the box body are cooled by circulating cooling water. After the experiment is finished, the ultrasonic medium liquid in the box body can be discharged through the liquid discharge port.
Preferably, the box body comprises a double-layer glass, a cup cover and a mounting flange, the double-layer glass comprises an inner cylinder, an outer cylinder, an upper ring cover and a lower ring cover, the inner cylinder, the outer cylinder, the upper ring cover and the lower ring cover enclose a sealed annular cavity, the outer cylinder is provided with a water inlet and a water outlet which are communicated with the annular cavity, the water inlet is connected with an outlet of an external cooling water supply mechanism, the water outlet is connected with an inlet of the external cooling water supply mechanism, the external cooling water supply mechanism is used for supplying circulating cooling water to the annular cavity, the cup cover is detachably arranged at the top end of the double-layer glass, the rotating motor is mounted on the cup cover, the lower part of the double-layer glass is connected with the amplitude transformer through the mounting flange, and a plurality of first sealing rings are arranged between the mounting flange and the lower part of the double-layer glass, and a plurality of second sealing rings are arranged between the mounting flange and the amplitude transformer. Through letting in recirculated cooling water in double-deck glass cup, take away the heat that produces when the ultrasonic wave sends out ripples, simple structure, the cooling effect is good.
Preferably, the mounting flange includes an axial flange ring and a radial flange ring which are integrally arranged, the axial flange ring is sleeved outside the lower portion of the double-layer glass cup, the double-layer glass cup and the axial flange ring clamp the plurality of first seal rings internally and externally, the bottom end of the double-layer glass cup is supported by the radial flange ring, the radial flange ring is sleeved outside the amplitude transformer, the liquid discharge port is arranged on the radial flange ring, a radial positioning ring is fixed on the outer periphery of the amplitude transformer, the radial flange ring and the radial positioning ring clamp one of the second seal rings up and down, the radial positioning ring and an annular pressing plate clamp the other of the second seal rings up and down, and the annular pressing plate is fixed on the radial positioning ring. The mounting flange with the specific structure is connected with the double-layer glass cup and the amplitude transformer, so that the double-layer glass cup and the amplitude transformer can be conveniently mounted and replaced. In addition, the second sealing ring is combined with the design of the radial flange ring, a labyrinth sealing structure can be formed, and the effect of preventing the leakage of the ultrasonic medium liquid is better.
Preferably, a motor cover is arranged on the outer side of the rotating motor, and a motor switch and an aviation plug are mounted on the motor cover.
Preferably, the upside of centrifuging tube adapter be provided with the centrifuging tube clamp plate, the centrifuging tube clamp plate install rotating electrical machines's output end on, the centrifuging tube clamp plate be used for compressing tightly the centrifuging tube adapter on the centrifuging tube of installation. The design of centrifuging tube clamp plate can effectively solve rocking or showy problem of centrifuging tube in supersound media liquid among the experimentation.
Preferably, the transducer is fixed at the lower end of the amplitude transformer through a connecting screw.
Compared with the prior art, the invention has the following advantages: the refrigeration type ultrasonic crusher is a non-contact type ultrasonic crusher, and when a sample is subjected to ultrasonic crushing, the amplitude transformer of the refrigeration type ultrasonic crusher is not contacted with the sample, so that the sample can be prevented from being polluted. The non-contact refrigeration type ultrasonic crusher separates the circulating cooling water from the ultrasonic medium liquid, namely the circulating cooling water is arranged on the periphery of the box body to cool the box body, and the ultrasonic medium liquid is arranged in the box body for ultrasonic conduction, so that the problem that the ultrasonic cavitation effect is influenced by unnecessary ultrasonic conduction of the flowing circulating cooling water can be effectively solved. In addition, the non-contact refrigeration type ultrasonic crusher has large power selection range of the amplitude transformer, the high-power amplitude transformer can be used as a wave generation source, the upper end surface of the amplitude transformer is a wave generation surface, glue required by the traditional wave generation is not required to be coated on the surface of the wave generation surface, and zero loss of energy conduction can be realized. The non-contact refrigeration type ultrasonic crusher can simultaneously carry out non-contact treatment on one or more samples under the condition that the amplitude transformer is fixed, and the treatment consistency is good.
Drawings
FIG. 1 is a top view of a non-contact refrigerated ultrasonic pulverizer of an embodiment;
FIG. 2 is a cross-sectional view taken along line A-A of FIG. 1;
fig. 3 is an enlarged view of fig. 2 at B.
Detailed Description
The invention is described in further detail below with reference to the accompanying examples.
The non-contact refrigeration type ultrasonic pulverizer comprises a box body, an amplitude transformer 2, an energy converter 3 and a rotating motor 4, wherein the rotating motor 4 is installed on the upper side of the box body, a motor cover 41 is arranged on the outer side of the rotating motor 4, a motor switch 42 and an aviation plug 43 are installed on the motor cover 41, the output end of the rotating motor 4 vertically extends into the box body to be connected with a centrifuge tube adapter 5, one or more hole sites for installing centrifuge tubes 51 are arranged on the centrifuge tube adapter 5, a centrifuge tube pressing plate 52 is arranged on the upper side of the centrifuge tube adapter 5, the centrifuge tube pressing plate 52 is installed on the output end of the rotating motor 4, the centrifuge tube pressing plate 52 is used for pressing the centrifuge tubes 51 installed on the centrifuge tube adapter 5, the energy converter 3 is vertically fixed at the lower end of the amplitude transformer 2 through a connecting screw 31, the upper end of the amplitude transformer 2 vertically extends into the box body, and the upper end of the amplitude transformer 2 is positioned below the centrifuge tube adapter 5, the box body is internally provided with ultrasonic medium liquid, the bottom of the box body is provided with a liquid outlet 10, and the periphery of the box body is provided with circulating cooling water.
In the embodiment, the box body comprises a double-layer glass 1, a glass cover 18 and a mounting flange 6, the double-layer glass 1 comprises an inner cylinder 11, an outer cylinder 12, an upper ring cover 13 and a lower ring cover 14, the inner cylinder 11, the outer cylinder 12, the upper ring cover 13 and the lower ring cover 14 enclose a sealed annular cavity 15, the outer cylinder 12 is provided with a water inlet 16 and a water outlet 17 which are communicated with the annular cavity 15, the water inlet 16 is connected with an outlet of an external cooling water supply mechanism, the water outlet 17 is connected with an inlet of the external cooling water supply mechanism, the external cooling water supply mechanism is used for supplying circulating cooling water to the annular cavity 15, the glass cover 18 is detachably arranged at the top end of the double-layer glass 1, a rotating motor 4 is arranged on the glass cover 18, the lower part of the double-layer glass 1 is connected with an amplitude transformer 2 through the mounting flange 6, two first sealing rings 71 are arranged between the mounting flange 6 and the lower part of the double-layer glass 1, two second sealing rings 72 are arranged between the mounting flange 6 and the horn 2.
In this embodiment, the mounting flange 6 includes an axial flange ring 61 and a radial flange ring 62 that are integrally disposed, the axial flange ring 61 is sleeved on the outer side of the lower portion of the double-layer glass cup 1, the two first sealing rings 71 are clamped between the inner side and the outer side of the double-layer glass cup 1 and the axial flange ring 61, the bottom end of the double-layer glass cup 1 is supported by the radial flange ring 62, the radial flange ring 62 is sleeved on the outer side of the amplitude transformer 2, the liquid discharge port 10 is disposed on the radial flange ring 62, the radial positioning ring 21 is fixed on the outer periphery of the amplitude transformer 2, the radial flange ring 62 and the radial positioning ring 21 clamp one second sealing ring 72 from top to bottom, the radial positioning ring 21 and an annular pressing plate clamp the other second sealing ring 72 from top to bottom, and the annular pressing plate is fixed on the radial positioning ring 21.
The non-contact refrigeration type ultrasonic crusher can simultaneously process one or more samples under the condition that the amplitude transformer 2 is fixed. The centrifugal tube 51 filled with the sample is mounted on the centrifugal tube adapter 5 and is tightly pressed by the centrifugal tube pressing plate 52, and after the ultrasonic medium liquid is filled in the box body, the sample can be processed in a non-contact manner, and the processing consistency is good. In the experiment process, the ultrasonic medium liquid and the centrifugal tube 51 in the box body are cooled by circulating cooling water. After the experiment is finished, the ultrasonic medium liquid in the box body can be discharged through the liquid discharge port 10.

Claims (6)

1. The utility model provides a non-contact refrigeration formula ultrasonic grinder, its characterized in that, includes box, amplitude transformer, transducer and rotating electrical machines, the rotating electrical machines install the upside of box, the vertical income of output of rotating electrical machines the box in link to each other with a centrifuging tube adapter, the centrifuging tube adapter on be equipped with one or more hole sites that are used for installing the centrifuging tube, the transducer vertical fix the lower extreme of amplitude transformer, the upper end of amplitude transformer vertical stretch into the box in, the upper end of amplitude transformer be located the below of centrifuging tube adapter, the box in installed ultrasonic medium liquid, the bottom of box be provided with the leakage fluid dram, the periphery of box be provided with recirculated cooling water.
2. The non-contact refrigeration type ultrasonic crusher as claimed in claim 1, wherein the box body comprises a double-layer glass, a cup cover and a mounting flange, the double-layer glass comprises an inner cylinder, an outer cylinder, an upper ring cover and a lower ring cover, the inner cylinder, the outer cylinder, the upper ring cover and the lower ring cover enclose a sealed annular cavity, the outer cylinder is provided with a water inlet and a water outlet which are communicated with the annular cavity, the water inlet is connected with an outlet of an external cooling water supply mechanism, the water outlet is connected with an inlet of the external cooling water supply mechanism, the external cooling water supply mechanism is used for supplying circulating cooling water to the annular cavity, the cup cover is detachably arranged at the top end of the double-layer glass, the rotating motor is arranged on the cup cover, and the lower part of the double-layer glass is connected with the amplitude transformer through the mounting flange, a plurality of first sealing rings are arranged between the mounting flange and the lower part of the double-layer glass cup, and a plurality of second sealing rings are arranged between the mounting flange and the amplitude transformer.
3. The non-contact refrigeration type ultrasonic crusher as claimed in claim 2, wherein said mounting flange comprises an axial flange ring and a radial flange ring which are integrally arranged, said axial flange ring is sleeved outside the lower portion of said double-layer glass, said double-layer glass and said axial flange ring clamp said plurality of first sealing rings inside and outside, the bottom end of said double-layer glass is supported by said radial flange ring, said radial flange ring is sleeved outside said horn, said drain port is arranged on said radial flange ring, a radial positioning ring is fixed on the outer periphery of said horn, said radial flange ring and said radial positioning ring clamp one of said second sealing rings above and below, said radial positioning ring and an annular pressing plate clamp the other of said second sealing rings above and below, the annular pressing plate is fixed on the radial positioning ring.
4. The non-contact refrigeration type ultrasonic pulverizer as claimed in claim 2, wherein a motor cover is provided outside the rotating motor, and a motor switch and an aviation plug are mounted on the motor cover.
5. The non-contact refrigeration type ultrasonic pulverizer as claimed in claim 1, wherein a centrifuge tube pressing plate is arranged on the upper side of the centrifuge tube adapter, the centrifuge tube pressing plate is installed on the output end of the rotating motor, and the centrifuge tube pressing plate is used for pressing the centrifuge tube installed on the centrifuge tube adapter.
6. A non-contact refrigerated ultrasonic pulverizer as claimed in claim 1 wherein said transducer is secured to the lower end of said horn by a connecting screw.
CN202110906300.6A 2021-08-09 2021-08-09 Non-contact refrigeration type ultrasonic pulverizer Pending CN113740127A (en)

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Application Number Priority Date Filing Date Title
CN202110906300.6A CN113740127A (en) 2021-08-09 2021-08-09 Non-contact refrigeration type ultrasonic pulverizer

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Application Number Priority Date Filing Date Title
CN202110906300.6A CN113740127A (en) 2021-08-09 2021-08-09 Non-contact refrigeration type ultrasonic pulverizer

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CN113740127A true CN113740127A (en) 2021-12-03

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115287180A (en) * 2022-08-02 2022-11-04 江苏百航超声科技有限公司 Ultrasonic DNA breaks appearance

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1923329A (en) * 2005-08-29 2007-03-07 北京弘祥隆生物技术开发有限公司 Multipurpose thermostatic ultrasonic extractor
CN204237799U (en) * 2014-11-06 2015-04-01 成都康华生物制品有限公司 A kind of Ultrasonic cell smash
CN205443320U (en) * 2015-12-28 2016-08-10 南京先欧仪器制造有限公司 Non -contact accuse temperature automatic focusing ultrasonic crashing appearance
CN106362628A (en) * 2016-11-01 2017-02-01 绍兴文理学院 Noncontact type high-frequency ultrasonic dispersing device
CN107036919A (en) * 2017-03-31 2017-08-11 中国矿业大学 The experimental provision and experimental method of a kind of utilization ultrasonic exciting fractured rock
CN108504564A (en) * 2018-05-22 2018-09-07 南京赛博生物科技有限公司 A kind of integrated ultrasonic cell disruption instrument of miniaturization
CN209006114U (en) * 2018-10-12 2019-06-21 上海生析超声仪器有限公司 Non-contact type ultrasonic processor
CN209778885U (en) * 2019-02-27 2019-12-13 广东华鸿科技有限公司 Cooling system of ultrasonic cell crusher
CN210163459U (en) * 2019-04-22 2020-03-20 南京赛飞生物科技有限公司 Liquid crystal type ultrasonic wave breaker

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1923329A (en) * 2005-08-29 2007-03-07 北京弘祥隆生物技术开发有限公司 Multipurpose thermostatic ultrasonic extractor
CN204237799U (en) * 2014-11-06 2015-04-01 成都康华生物制品有限公司 A kind of Ultrasonic cell smash
CN205443320U (en) * 2015-12-28 2016-08-10 南京先欧仪器制造有限公司 Non -contact accuse temperature automatic focusing ultrasonic crashing appearance
CN106362628A (en) * 2016-11-01 2017-02-01 绍兴文理学院 Noncontact type high-frequency ultrasonic dispersing device
CN107036919A (en) * 2017-03-31 2017-08-11 中国矿业大学 The experimental provision and experimental method of a kind of utilization ultrasonic exciting fractured rock
CN108504564A (en) * 2018-05-22 2018-09-07 南京赛博生物科技有限公司 A kind of integrated ultrasonic cell disruption instrument of miniaturization
CN209006114U (en) * 2018-10-12 2019-06-21 上海生析超声仪器有限公司 Non-contact type ultrasonic processor
CN209778885U (en) * 2019-02-27 2019-12-13 广东华鸿科技有限公司 Cooling system of ultrasonic cell crusher
CN210163459U (en) * 2019-04-22 2020-03-20 南京赛飞生物科技有限公司 Liquid crystal type ultrasonic wave breaker

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115287180A (en) * 2022-08-02 2022-11-04 江苏百航超声科技有限公司 Ultrasonic DNA breaks appearance
CN115287180B (en) * 2022-08-02 2024-05-07 江苏百航超声科技有限公司 Ultrasonic wave DNA breaks appearance

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