CN113721175A - Semi-automatic tuning system and tuning method for nuclear magnetic resonance - Google Patents
Semi-automatic tuning system and tuning method for nuclear magnetic resonance Download PDFInfo
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- CN113721175A CN113721175A CN202110803019.XA CN202110803019A CN113721175A CN 113721175 A CN113721175 A CN 113721175A CN 202110803019 A CN202110803019 A CN 202110803019A CN 113721175 A CN113721175 A CN 113721175A
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- 238000005481 NMR spectroscopy Methods 0.000 title claims abstract description 47
- 238000000034 method Methods 0.000 title claims abstract description 10
- 238000001208 nuclear magnetic resonance pulse sequence Methods 0.000 claims description 4
- 239000000523 sample Substances 0.000 description 32
- 238000010586 diagram Methods 0.000 description 4
- 239000000696 magnetic material Substances 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 2
- 239000010963 304 stainless steel Substances 0.000 description 1
- 229910001369 Brass Inorganic materials 0.000 description 1
- 229910000589 SAE 304 stainless steel Inorganic materials 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000010951 brass Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
- G01R33/36—Electrical details, e.g. matching or coupling of the coil to the receiver
- G01R33/3628—Tuning/matching of the transmit/receive coil
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- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Abstract
The invention relates to a semi-automatic tuning system and a tuning method for nuclear magnetic resonance, which comprise a control system and a driving system, wherein: the control system is configured to: acquiring operation information input by a user, generating a control signal and sending the control signal to the driving system; the drive system is configured to: and driving the nuclear magnetic resonance tuning rod to move in response to receiving the control signal. By tuning through the semi-automatic tuning system disclosed by the invention, not only is tuning convenient and fast, but also excessive tuning can be avoided.
Description
Technical Field
The disclosure relates to the technical field of nuclear magnetic resonance, in particular to a nuclear magnetic resonance semi-automatic tuning system and a tuning method.
Background
Since the discovery in 1946, the technology of nuclear magnetic resonance has been developed for over 70 years, and is continuously developed to high field and digitalization. At present, nuclear magnetic resonance spectrometers at home and abroad have high popularity, are indispensable hardware facilities of colleges and universities and scientific research institutions, and are also widely applied to various fields of chemistry and chemical industry, medicines, high polymer materials, polysaccharides, macromolecular bioscience and the like. The nuclear magnetic resonance spectrometer is developed from the earliest permanent magnet to the current high-resolution superconducting magnet from a low field to a high field, and is developed from 30MHz, which is originally proposed by Warran corporation, to the current Bruk 1.2GHz, so that the sensitivity and the resolution are greatly improved. In order to meet different requirements, nuclear magnetic resonance probes have been developed rapidly, and various probes have diversified types, such as three-core, four-core and multi-core probes, liquid, solid and semisolid probes, reverse probes, forward probes, temperature-changing probes, living probes and the like.
Probe tuning is the first operation of performing nmr examination of a sample. And tuning the probe to the resonance frequency corresponding to each atomic nucleus according to the atomic nucleus to be detected and the experiment type. At present, nuclear magnetic resonance probe tuning modes include two types: one is the traditional manual tuning and the other is the full automatic tuning.
Most instruments on the market use the traditional manual means of tuning the probe with the tuning rod at the bottom of the magnet probe. Due to the strong magnetic field, the magnet is at a distance (about six meters) from the workstation where the data is collected. And the operator takes a sample from the workstation, puts the sample into the magnet probe, returns to the workstation to operate the software tuning interface and selects the atomic nucleus to be tuned. Then the operator needs to return to the magnet, squat under the magnet probe and manually rotate the tuning rod at the bottom of the probe by using a special tuning tool, and then the operator returns to the workstation to observe the tuning signal diagram, or turns the display screen of the workstation to the magnet in advance to remotely observe the tuning signal diagram until the target position is tuned. And only one atomic nucleus can be tuned in one tuning operation, and when the multi-nuclear tuning is carried out, the next nuclear nucleus to be tuned is sequentially selected by a tuning interface of the workstation to carry out multiple operations. Manual tuning is inconvenient to handle and view because of distance.
The full-automatic tuning completes the probe tuning through automatic tuning software. At present, only a small part of novel nuclear magnetic resonance instruments are equipped with full-automatic tuning systems when being purchased. Bruker, Agilent and Japan electron are three major brands of the current high-field nuclear magnetic resonance spectrometer, and the automatic tuning system of the Bruker, Agilent and Japan electron is expensive and has higher maintenance and accessory cost. The change of tuning positions can be influenced by the dissolution states, temperatures, solvents, salt concentrations, different experiment types and the like of different samples, the resonance frequency and the positions can be calculated through software in full-automatic tuning, and the tuning rod is inevitably damaged due to excessive tuning after receiving instructions by the tuning rod caused by the calculation disorder of complex pulse power of the samples.
Disclosure of Invention
The technical problem that this disclosure will solve is: on one hand, manual tuning operation and observation inconvenience; on the other hand, fully automatic tuning equipment is expensive and may be subject to over-tuning.
The invention provides a semi-automatic nuclear magnetic resonance tuning system for solving the technical problems.
Specifically, the present disclosure proposes the following technical solutions:
a semi-automatic nuclear magnetic resonance tuning system comprising a control system and a drive system, wherein:
the control system is configured to: acquiring operation information input by a user, generating a control signal and sending the control signal to the driving system;
the drive system is configured to: and driving the nuclear magnetic resonance tuning rod to move in response to receiving the control signal.
Optionally, the tuning system above, wherein the drive system comprises a driver, the control system is further configured to: and receiving and storing driver information which is sent by a driving system and corresponds to the position of the nuclear magnetic resonance tuning rod.
Optionally, the tuning system above, wherein the control system is further configured to: and obtaining tuning limit information set by a user, and displaying early warning information when the nuclear magnetic resonance tuning rod is located at a limit position indicated by the tuning limit information.
Optionally, in the tuning system, the warning information includes an image, text and/or audio.
Optionally, in the tuning system, the driving system comprises at least one motor, and the control signal comprises a motor identifier and a pulse sequence.
Optionally, in the tuning system described above, the driving system includes a motor, a flexible shaft and a tuning rod joint, and two ends of the flexible shaft are respectively connected to the motor and the tuning rod joint.
Optionally, in the tuning system, the flexible shaft is a non-magnetic or weakly magnetic flexible shaft; the tuning rod joint is a non-magnetic joint.
In another aspect, the present disclosure provides a method for tuning the tuning system, including the following steps:
the control system acquires operation information input by a user, generates a control signal and sends the control signal to the driving system;
and the driving system drives the nuclear magnetic resonance tuning rod to move corresponding to the received control signal.
Optionally, the tuning method further includes the steps of:
the control system detects the storage operation input by a user, and receives and stores the driver information which is sent by the driving system and corresponds to the position of the nuclear magnetic resonance tuning rod.
Optionally, the method further includes:
the control system acquires tuning limit information set by a user, and when the nuclear magnetic resonance tuning rod is located at a limit position indicated by the tuning limit information, early warning information is presented.
The beneficial effects of this disclosure include:
the semi-automatic tuning system provided by some embodiments of the present disclosure can solve the problem of inconvenience caused by manual tuning, and an operator does not need to repeatedly walk between a workstation and a magnet, and can automatically realize the switching of each atomic nucleus, and the semi-automatic tuning system is simple and convenient to operate and easy to observe.
According to the semi-automatic tuning system provided by some embodiments of the disclosure, a traditional manual tuning mode can be upgraded to a semi-automatic tuning mode, the original instrument is not required to be changed, the normal operation of the original instrument and equipment is not influenced, and the equipment is not damaged.
Some embodiments of the present disclosure provide a semi-automatic tuning system that can avoid the risk of excessive damage to the tuning rod due to the disturbance of the fully automatic tuning calculation.
Drawings
Fig. 1 is a schematic diagram of a bottom tuning rod of a prior art manual tuning probe, which includes six tuning rods, where 1: X-Band tuning rod, 2: X-Match tuning rod, 3: X-Tune1 tuning bar, 4: X-Tune2 tuning bar, 5: 1H-Match tuning rod, 6: 1H-Tune tuning rod.
FIG. 2 is a schematic view of a nuclear magnetic resonance semi-automatic tuning system coupled to a tuning rod according to one embodiment of the present disclosure.
FIG. 3 is a nuclear magnetic resonance semi-automatic tuning system software interface according to one embodiment of the present disclosure.
Detailed Description
The present disclosure is described in further detail below with reference to the accompanying drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the relevant invention and not restrictive of the invention. It should be noted that, for convenience of description, only the portions related to the related invention are shown in the drawings.
As described above, the present disclosure is directed to provide a semi-automatic nuclear magnetic resonance tuning system to solve the technical problems of inconvenient manual tuning.
Figure 1 shows a schematic view (bottom view) of the bottom of a manually tuned nmr probe.
The bottom of the probe is provided with six nuclear magnetic resonance tuning rods, and the tuning rods are selectively rotated clockwise or anticlockwise to tune aiming at different atomic nuclei to be measured. The X-Band tuning rod 1 is used for adjusting different nuclear resonance frequency ranges, the 1H-Match tuning rod 5 and the 1H-Tune tuning rod 6 are used for tuning two kinds of detecting nuclei of H1 and F19, and the X-Match tuning rod 2, the X-Tune1 tuning rod 3 and the X-Tune2 tuning rod 4 are used for tuning other various common nuclei, such as C13, P31, N15, Si29, O17, Se77 and the like.
FIG. 2 shows a schematic structural view of a nuclear magnetic resonance semi-automatic tuning system connected to the bottom tuning rod of the probe of FIG. 1 according to one embodiment of the present disclosure.
The nuclear magnetic resonance semi-automatic tuning system comprises a control system and a driving system, one end of the driving system is connected with the control system, the other end of the driving system is connected to a tuning rod at the bottom of the probe through a tuning rod joint, six tuning rods are arranged at the bottom of the probe, and correspondingly, six tuning rod joints are arranged in the driving system and connected with the tuning rods. The user inputs the operation information of the driving system to the control system according to the atomic nucleus to be detected, the control system generates a control signal according to the operation information after receiving the operation information and sends the control signal to the driving system, and the driving system drives the tuning rod to move after receiving the control signal sent by the control system, so that the probe is tuned. The control system comprises an upper computer which can be placed at a position close to the nuclear magnetic resonance workstation, so that when the atomic nucleus is tuned through the semi-automatic tuning system, a user can simultaneously observe tuning signals displayed by the workstation computer, and when tuning is not completed, the semi-automatic tuning system can be continuously used for tuning until tuning is completed without walking to the probe for many times.
In some embodiments, the control system comprises an upper computer and a controller, and the drive system comprises a driver, a motor, a flexible shaft and a tuning rod joint. The user inputs the running information of the motor into the upper computer, and the upper computer sends the running information to the controller. The controller receives the operation information from the upper computer, generates a control signal and sends the control signal to the driver. The driver controls the motor to rotate according to the control signal, the rotation of the motor drives the tuning rod joint to rotate through the flexible shaft, and then the nuclear magnetic resonance tuning rod is driven to rotate, so that the tuning of the probe is realized. The semi-automatic tuning system drives six nuclear magnetic resonance tuning rods to rotate through six motors respectively, each motor is provided with a unique motor identifier which is distinguished from each other, a control signal generated by the controller comprises the motor identifiers and a pulse sequence, and the driver controls the motors corresponding to the received motor identifiers to operate. Here, the pulse sequence includes motor operation direction and motor operation angular displacement information, and the operation direction includes counterclockwise or clockwise. In order not to interfere detection, the flexible shaft and the tuning rod joint are both made of weak magnetic or non-magnetic materials, for example, the flexible shaft can be made of weak magnetic materials such as 304 stainless steel, and the tuning rod joint can be made of non-magnetic materials such as brass.
In some embodiments, the control system receives and stores actuator information corresponding to the position of the nuclear magnetic resonance tuning bar sent by the actuation system. The driver information comprises a motor rotation direction and a motor rotation angle, and the motor rotation direction and the motor rotation number correspond to the rotation direction and the rotation number of the nuclear magnetic resonance tuning rod one by one, so that the position of the nuclear magnetic resonance tuning rod can be determined. When a user operates for the first time, driver information corresponding to the position of the nuclear magnetic resonance tuning rod when tuning corresponding to an atomic nucleus to be tested is completed is stored in the control system, when the same atomic nucleus is tested next time, the driver information corresponding to the position of the nuclear magnetic resonance tuning rod corresponding to the atomic nucleus can be extracted to serve as motor operation information, a plurality of motors rotate simultaneously and adjust a plurality of tuning rods, and tuning time is saved.
Because the number of turns of the nuclear magnetic resonance tuning rod which can rotate on the probe is fixed, different tuning rods have different numbers of turns, in some embodiments, a user can set tuning limit information in the control system, and when the nuclear magnetic resonance tuning rod is located at a limit position indicated by the limit information, the control system presents early warning information, for example, images, texts and/or audios are used for prompting the nuclear magnetic resonance tuning rod of the user to reach the limit position, so that equipment damage caused by over-operation of a motor is prevented.
Fig. 3 illustrates a software interface of a host computer of a semi-automatic nuclear magnetic resonance tuning system according to an embodiment of the present disclosure. The first time a user uses a semi-automatic nuclear magnetic resonance tuning system, an "initialization" is required to set the relative zero point. The relative zero point is driver information corresponding to the position of the nmr tuning bar when tuning of the standard sample of the nmr spectrometer is completed. After initialization, for the atomic nucleus to be tested for the first time, for example, the atomic nucleus to be tested is Si29, the position of the X-Band tuning rod 1 is firstly adjusted to the resonance frequency range of the atomic nucleus, the X-Band is selected, operation information of a driving system is input through coarse tuning and fine tuning, the control system sends a control signal to the driving system according to the operation information, and the motor corresponding to the X-Band tuning rod 1 rotates to drive the X-Band tuning rod 1 to rotate, so that the position of the X-Band tuning rod 1 is adjusted. After the tuning of the X-Band tuning rod 1 is finished, selecting a corresponding Si29 atomic nucleus in a channel of channel 2, clicking X-Match, X-Tune1 and X-Tune2 respectively, inputting the operation information of a driving system through coarse tuning and fine tuning, and tuning the X-Match tuning rod 2, the X-Tune1 tuning rod 3 and the X-Tune2 tuning rod 4. Observing a tuning signal diagram of the workstation to confirm whether tuning is finished, and if the tuning is not finished, continuing tuning; and if tuning is finished, continuing to select corresponding atomic nuclei (such as H1 nuclei) in the channel 1, then clicking H1-Match and H1-Tune respectively, inputting running information of a driving system through coarse tuning and fine tuning to Tune the 1H-Match tuning rod 5 and the 1H-Tune tuning rod 6, if tuning is finished, clicking Save, storing driver information corresponding to the joint position of the tuning rod at the moment, clicking and selecting the Si29 nuclei as the atomic nuclei to be tested when the Si29 nuclei are tested next time, automatically switching the extracted and stored driver information of the Si29 nuclei by the control system, and then finely tuning according to the conditions of the sample.
Claims (10)
1. A semi-automatic tuning system for nuclear magnetic resonance, comprising a control system and a drive system, wherein:
the control system is configured to: acquiring operation information input by a user, generating a control signal and sending the control signal to the driving system;
the drive system is configured to: and driving the nuclear magnetic resonance tuning rod to move in response to receiving the control signal.
2. The tuning system of claim 1, wherein the drive system comprises a driver, the control system further configured to: and receiving and storing driver information which is sent by a driving system and corresponds to the position of the nuclear magnetic resonance tuning rod.
3. The tuning system of claim 1 or 2, wherein the control system is further configured to: and obtaining tuning limit information set by a user, and displaying early warning information when the nuclear magnetic resonance tuning rod is located at a limit position indicated by the tuning limit information.
4. The tuning system of claim 3, wherein the pre-alert information comprises an image, text, and/or audio.
5. The tuning system of any one of claims 1-4, wherein the drive system comprises at least one motor, and the control signal comprises a motor identification and a pulse sequence.
6. The tuning system of any one of claims 1-5, wherein the drive system comprises a motor, a flexible shaft, and a tuning rod joint, wherein the flexible shaft is connected at two ends to the motor and the tuning rod joint, respectively.
7. The tuning system of claim 6, wherein the flexible shaft is a non-magnetic or weakly magnetic flexible shaft; the tuning rod joint is a non-magnetic joint.
8. A method of tuning a tuning system of any one of claims 1-7, comprising the steps of:
the control system acquires operation information input by a user, generates a control signal and sends the control signal to the driving system;
and the driving system drives the nuclear magnetic resonance tuning rod to move corresponding to the received control signal.
9. The tuning method of claim 8, further comprising the steps of:
the control system detects the storage operation input by a user, and receives and stores the driver information which is sent by the driving system and corresponds to the position of the nuclear magnetic resonance tuning rod.
10. The method according to claim 8 or 9, further comprising the step of:
the control system acquires tuning limit information set by a user, and when the nuclear magnetic resonance tuning rod is located at a limit position indicated by the tuning limit information, early warning information is presented.
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Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090230956A1 (en) * | 2008-03-11 | 2009-09-17 | Jim Finnigan | Switchable manual/motor-driven nmr tuning systems and methods |
CN103941757A (en) * | 2014-05-09 | 2014-07-23 | 中国航天科技集团公司烽火机械厂 | Potentiometer processing system and method |
CN104698023A (en) * | 2015-02-25 | 2015-06-10 | 中国科学技术大学 | Remote tuning device for electron paramagnetic resonance probe |
CN108872290A (en) * | 2018-04-24 | 2018-11-23 | 厦门大学 | A kind of small-sized nuclear magnetic resonance spectrometer rotates and upgrades the method and device of resolution ratio automatically |
CN109791185A (en) * | 2016-09-29 | 2019-05-21 | 海珀菲纳研究股份有限公司 | Radio-frequency coil tuning methods and equipment |
CN112545488A (en) * | 2020-12-07 | 2021-03-26 | 武汉联影生命科学仪器有限公司 | Tuning and matching device and method and magnetic resonance imaging equipment |
CN113030820A (en) * | 2021-04-25 | 2021-06-25 | 国仪量子(合肥)技术有限公司 | Table type continuous wave paramagnetic resonance spectrometer probe |
-
2021
- 2021-07-15 CN CN202110803019.XA patent/CN113721175A/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090230956A1 (en) * | 2008-03-11 | 2009-09-17 | Jim Finnigan | Switchable manual/motor-driven nmr tuning systems and methods |
CN103941757A (en) * | 2014-05-09 | 2014-07-23 | 中国航天科技集团公司烽火机械厂 | Potentiometer processing system and method |
CN104698023A (en) * | 2015-02-25 | 2015-06-10 | 中国科学技术大学 | Remote tuning device for electron paramagnetic resonance probe |
CN109791185A (en) * | 2016-09-29 | 2019-05-21 | 海珀菲纳研究股份有限公司 | Radio-frequency coil tuning methods and equipment |
CN108872290A (en) * | 2018-04-24 | 2018-11-23 | 厦门大学 | A kind of small-sized nuclear magnetic resonance spectrometer rotates and upgrades the method and device of resolution ratio automatically |
CN112545488A (en) * | 2020-12-07 | 2021-03-26 | 武汉联影生命科学仪器有限公司 | Tuning and matching device and method and magnetic resonance imaging equipment |
CN113030820A (en) * | 2021-04-25 | 2021-06-25 | 国仪量子(合肥)技术有限公司 | Table type continuous wave paramagnetic resonance spectrometer probe |
Non-Patent Citations (1)
Title |
---|
赵勇等: "微波铁氧体铁磁共振有效线宽扫频测量可调谐振腔设计", 《磁性材料及器件》 * |
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