CN113712506A - Intraocular pressure sensing system based on Moire patterns and intraocular pressure measuring method - Google Patents

Intraocular pressure sensing system based on Moire patterns and intraocular pressure measuring method Download PDF

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Publication number
CN113712506A
CN113712506A CN202111049252.XA CN202111049252A CN113712506A CN 113712506 A CN113712506 A CN 113712506A CN 202111049252 A CN202111049252 A CN 202111049252A CN 113712506 A CN113712506 A CN 113712506A
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CN
China
Prior art keywords
contact lens
moire
standard
intraocular pressure
concentric circles
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Pending
Application number
CN202111049252.XA
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Chinese (zh)
Inventor
邹文军
武志峰
杨广宇
张清
吴俊�
唐俊逸
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Southeast University
Wuxi No 2 Peoples Hospital
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Southeast University
Wuxi No 2 Peoples Hospital
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Application filed by Southeast University, Wuxi No 2 Peoples Hospital filed Critical Southeast University
Priority to CN202111049252.XA priority Critical patent/CN113712506A/en
Publication of CN113712506A publication Critical patent/CN113712506A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/16Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring intraocular pressure, e.g. tonometers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14Arrangements specially adapted for eye photography

Abstract

The invention discloses an intraocular pressure sensing system based on Moire, which comprises a contact lens, a standard comparison grating and a high-precision camera, wherein concentric circles are printed on the contact lens, the standard comparison grating is positioned between the high-precision camera and the contact lens during shooting, the plane of the standard comparison grating is perpendicular to the connecting line between the contact lens and the high-precision camera, the positions of the standard comparison grating and the contact lens are relatively fixed, the standard Moire is obtained firstly, then the Moire during measurement is obtained, and the Moire is compared with the standard Moire, so that whether the intraocular pressure is normal or not can be obtained. By adopting the intraocular pressure sensing system and the intraocular pressure measuring method based on Moire patterns, the phenomena of contact lens heating, eyeball resonance and the like can not be generated, and the scheme of the invention has low cost and simple operation flow.

Description

Intraocular pressure sensing system based on Moire patterns and intraocular pressure measuring method
Technical Field
The invention belongs to the technical field of intraocular pressure measurement, and particularly relates to an intraocular pressure sensing system and an intraocular pressure measuring method based on Moire patterns.
Background
There are many intraocular pressure sensing systems based on electrical properties, such as: the tonometer takes a graphene strain resistor as a core device, and an intraocular pressure system for realizing intraocular pressure wireless measurement through variable inductance/variable capacitance and the like. However, such devices tend to have problems:
1) there is a great deal of current energy converted to heat energy during the operation of the circuitry in the contact lens, thereby risking burning of the cornea.
2) Electromagnetic waves may resonate in the eyeball, thereby heating the inside of the eyeball, with the risk of causing diseases such as cataract.
The optical scheme based on Moire patterns does not generate the above-mentioned problems, and has low cost and simple operation flow.
Disclosure of Invention
The intraocular pressure sensing system based on Moire patterns comprises contact lenses printed with concentric circles, a standard comparison grating and a high-precision camera; the contact lens printed with the concentric circles comprises a contact lens body and concentric circle patterns printed on the surface of the contact lens body, wherein the distance between every two adjacent concentric circles is in the micrometer order of magnitude; the standard comparison grating comprises a transparent substrate and stripes printed on the surface of the substrate and having equal intervals; and the high-precision camera is used for shooting Moire patterns formed by the concentric circles on the contact lenses and the patterns of the standard comparison grating. When shooting, the standard comparison grating is positioned between the high-precision camera and the contact lenses, the plane of the standard comparison grating is perpendicular to the connecting line between the contact lenses and the high-precision camera, and the positions of the standard comparison grating and the contact lenses are relatively fixed.
Further, under normal eye pressure, the contact lens printed with concentric circles is worn on eyes of a person, a high-precision camera is used for shooting the contact lens and the standard comparison grating which are mutually overlapped, and at the overlapped part, the concentric circles on the contact lens and the stripes of the standard comparison grating form standard Moire patterns.
Further, when measuring intraocular pressure, a contact lens printed with concentric circles is worn on eyes, a high-precision camera is used to photograph the contact lens and the standard comparison grating which are mutually overlapped, at the overlapped part, the concentric circles on the contact lens and the stripes of the standard comparison grating form moire patterns, and the moire patterns obtained by measurement are compared with the standard moire patterns, so that the change of intraocular pressure relative to normal intraocular pressure during measurement is obtained.
Has the advantages that: by adopting the intraocular pressure sensing system and the intraocular pressure measuring method based on Moire patterns, the phenomena of contact lens heating, eyeball resonance and the like can not be generated, and the scheme of the invention has low cost and simple operation flow.
Drawings
FIG. 1 is a schematic view of concentric circle printed contact lenses and a standard alignment grid of the present invention.
FIG. 2 is a schematic diagram of the Moire pattern formation of the present invention.
FIG. 3 is a graph of the change in Moire pattern with increasing intraocular pressure.
Detailed Description
The intraocular pressure sensing system based on Moire patterns comprises contact lenses printed with concentric circles, a standard comparison grating and a high-precision camera.
As shown in fig. 1, the contact lens printed with concentric circles comprises a contact lens body and a pattern of concentric circles printed on the surface of the contact lens body, wherein the distance between adjacent concentric circles is in the order of micrometers. The contact lens printed with the concentric circles has the characteristics of a contact lens body and has good elasticity, when the contact lens is worn, the surface printed with the concentric figures is outward, the contact lens printed with the concentric circles is arranged on the eyeball of a patient, and the distance between the adjacent concentric circles can be changed according to the change of intraocular pressure.
The standard comparison grating comprises a transparent substrate and stripes printed on the surface of the substrate and having equal intervals. The spacing of the stripes on the grid is similar to the spacing of the concentric circles on the contact lens for standard alignment.
And the high-precision camera is used for shooting Moire patterns formed by the concentric circles on the contact lenses and the patterns of the standard comparison grating.
Under normal eye pressure, the contact lens printed with concentric circles is worn on eyes of a person, the standard comparison grating is placed between the high-precision camera and the contact lens, the plane where the standard comparison grating is located is perpendicular to the connecting line between the contact lens and the high-precision camera, the position of the standard comparison grating and the position of the contact lens are relatively fixed, the high-precision camera is used for shooting the contact lens and the standard comparison grating which are mutually overlapped, and in the overlapping part, as shown in fig. 2, the concentric circles on the contact lens and the stripes of the standard comparison grating form standard Moire patterns. The standard Moire patterns are axisymmetric patterns, the symmetry axis is vertical to the strips of the standard contrast grating, the standard Moire patterns formed by the concentric circles and the strips of the grating are in a plurality of arc shapes, the opening direction of the arc shapes deviates from the direction of the concentric circles,
the principle of moire formation is that when two fringes close in spatial frequency are superimposed, the superimposed positions are gradually shifted due to the difference in fringe spacing, thereby forming a beat, and the filled portions constitute moire.
When the intraocular pressure is increased, the cornea expands, the contact lens deforms, so that the distance between concentric circles on the contact lens is increased, the distance between the concentric circles on the contact lens and the moire fringes formed by the standard comparison grating are unchanged in shape, when the size and the distance between the concentric circles on the contact lens are increased due to the increase of the intraocular pressure, the angle of the moire formed is gradually increased, and the arc-shaped opening of the moire becomes large. As shown in fig. 3, the distance between the concentric circles increases from left to right, and the arc-shaped openings of the moire pattern also increases. A Moire pattern formed by concentric circles on the contact lens and the pattern of the standard comparison grating is shot by the precision camera, the shot Moire pattern is compared with the standard Moire pattern, and if the arc-shaped opening of the Moire pattern is larger, the intraocular pressure is considered to be increased.
The intraocular pressure measuring method based on Moire provided by the invention specifically comprises the following steps:
step 1, obtaining standard Moire patterns;
under normal eye pressure, the contact lens printed with concentric circles is worn on eyes of a person, a high-precision camera is used for shooting the contact lens and the standard comparison grating which are mutually overlapped, and at the overlapped part, the concentric circles on the contact lens and the standard comparison grating form standard Moire patterns.
Step 2, acquiring Moire patterns during measurement;
when measuring intraocular pressure, the contact lens printed with concentric circles is worn on human eyes, a high-precision camera is used for shooting the contact lens and the standard comparison grating which are mutually overlapped, and at the overlapped part, the concentric circles on the contact lens and the stripes of the standard comparison grating form Moire patterns during measurement.
Step 3, comparing the standard moire pattern with the moire pattern during measurement;
and comparing the Moire obtained by measurement with the standard Moire, wherein the larger the arc-shaped opening of the Moire is, the higher the intraocular pressure is, so that the change of the intraocular pressure relative to the normal intraocular pressure during measurement is known.

Claims (5)

1. The intraocular pressure sensing system based on Moire patterns is characterized by comprising contact lenses printed with concentric circles, a standard comparison grating and a high-precision camera;
the contact lens printed with the concentric circles comprises a contact lens body and concentric circle patterns printed on the surface of the contact lens body;
the standard comparison grating comprises a transparent substrate and stripes printed on the surface of the substrate and having equal intervals;
the high-precision camera is used for shooting Moire patterns formed by concentric circles on the contact lenses and the patterns of the standard comparison grating; when shooting, the standard comparison grating is positioned between the high-precision camera and the contact lenses, the plane of the standard comparison grating is perpendicular to the connecting line between the contact lenses and the high-precision camera, and the positions of the standard comparison grating and the contact lenses are relatively fixed.
2. The intraocular pressure sensing system based on moire at the base of claim 1, wherein the contact lens with concentric circles printed thereon is worn on the eye under normal eye pressure, and the high precision camera is used to photograph the contact lens and the standard alignment grating in registration with each other, wherein the concentric circles on the contact lens and the fringes of the standard alignment grating form a standard moire at the registration portion.
3. The intraocular pressure sensing system according to claim 1, wherein the intraocular pressure is measured by wearing a contact lens having concentric circles printed thereon on a human eye, photographing the contact lens and the standard alignment grating with each other using a high-precision camera, forming a moir e in the overlapped portion between the concentric circles on the contact lens and the standard alignment grating, and comparing the obtained moir e with the standard moir e to know a change in intraocular pressure with respect to the normal intraocular pressure at the time of measurement.
4. Intraocular pressure sensing system based on moire at the base of claim 1, characterized in that the distance between adjacent concentric circles is in the order of micrometers.
5. Tonometry method based on moire, characterized in that it is based on the measurement system of claim 1, comprising in particular the following steps:
step 1, obtaining standard Moire patterns;
under normal eye pressure, wearing the contact lens printed with concentric circles on eyes, shooting the contact lens and the standard comparison grating which are mutually overlapped by using a high-precision camera, wherein at the overlapped part, the concentric circles on the contact lens and the stripes of the standard comparison grating form standard Moire patterns;
step 2, acquiring Moire patterns during measurement;
when measuring intraocular pressure, wearing a contact lens printed with concentric circles on human eyes, shooting the contact lens and the standard comparison grating which are mutually overlapped by using a high-precision camera, wherein at the overlapped part, the concentric circles on the contact lens and the stripes of the standard comparison grating form Moire patterns during measurement;
step 3, comparing the standard moire pattern with the moire pattern during measurement;
and comparing the Moire obtained by measurement with the standard Moire, wherein the larger the arc-shaped opening of the Moire is, the higher the intraocular pressure is, so that the change of the intraocular pressure relative to the normal intraocular pressure during measurement is known.
CN202111049252.XA 2021-09-08 2021-09-08 Intraocular pressure sensing system based on Moire patterns and intraocular pressure measuring method Pending CN113712506A (en)

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CN202111049252.XA CN113712506A (en) 2021-09-08 2021-09-08 Intraocular pressure sensing system based on Moire patterns and intraocular pressure measuring method

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Application Number Priority Date Filing Date Title
CN202111049252.XA CN113712506A (en) 2021-09-08 2021-09-08 Intraocular pressure sensing system based on Moire patterns and intraocular pressure measuring method

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3206410A1 (en) * 1982-02-23 1983-09-01 Fa. Carl Zeiss, 7920 Heidenheim Device for topography of the ocular fundus
US20070291997A1 (en) * 2004-09-29 2007-12-20 Positive Eye-D Ltd. Corneal Biometry Apparatus and Method
EP2305100A1 (en) * 2008-06-06 2011-04-06 Consejo Superior De Investigaciones Científicas Sensor contact lens, system for the non-invasive monitoring of intraocular pressure and method for measuring same
JP2013533046A (en) * 2010-07-30 2013-08-22 オフティマリア Integrated flexible passive sensor in soft contact lens for intraocular pressure monitoring
FR3001378A1 (en) * 2013-01-25 2014-08-01 Ophtimalia Sensor for incorporation of intraocular pressure in flexible contact lens to diagnose glaucoma in patient, has inductor provided in star geometry and including series of branches and valleys, where end of each branch and valley is rounded
US20150073253A1 (en) * 2013-09-06 2015-03-12 Syntec Technologies, Inc. Contact lens for intraocular pressure measurement
CN107850792A (en) * 2015-04-30 2018-03-27 王伦 The central contact lenses without moire pattern, the analysis method of change and the monitoring system of varieties of intraocular pressure of its moire pattern
CN108065909A (en) * 2017-12-29 2018-05-25 圆环有限公司 For determining the contact lenses device of cornea shape, system and intraocular pressure method for monitoring

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3206410A1 (en) * 1982-02-23 1983-09-01 Fa. Carl Zeiss, 7920 Heidenheim Device for topography of the ocular fundus
US20070291997A1 (en) * 2004-09-29 2007-12-20 Positive Eye-D Ltd. Corneal Biometry Apparatus and Method
EP2305100A1 (en) * 2008-06-06 2011-04-06 Consejo Superior De Investigaciones Científicas Sensor contact lens, system for the non-invasive monitoring of intraocular pressure and method for measuring same
JP2013533046A (en) * 2010-07-30 2013-08-22 オフティマリア Integrated flexible passive sensor in soft contact lens for intraocular pressure monitoring
FR3001378A1 (en) * 2013-01-25 2014-08-01 Ophtimalia Sensor for incorporation of intraocular pressure in flexible contact lens to diagnose glaucoma in patient, has inductor provided in star geometry and including series of branches and valleys, where end of each branch and valley is rounded
US20150073253A1 (en) * 2013-09-06 2015-03-12 Syntec Technologies, Inc. Contact lens for intraocular pressure measurement
CN107850792A (en) * 2015-04-30 2018-03-27 王伦 The central contact lenses without moire pattern, the analysis method of change and the monitoring system of varieties of intraocular pressure of its moire pattern
CN108065909A (en) * 2017-12-29 2018-05-25 圆环有限公司 For determining the contact lenses device of cornea shape, system and intraocular pressure method for monitoring

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