CN113599716A - Optical medical device - Google Patents
Optical medical device Download PDFInfo
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- CN113599716A CN113599716A CN202111026832.7A CN202111026832A CN113599716A CN 113599716 A CN113599716 A CN 113599716A CN 202111026832 A CN202111026832 A CN 202111026832A CN 113599716 A CN113599716 A CN 113599716A
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Classifications
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- A61N2005/063—Radiation therapy using light comprising light transmitting means, e.g. optical fibres
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Abstract
The application discloses light medical treatment device includes: a central shaft; the sealing adjusting cavity is wrapped at the end part of the central shaft; the flexible light source is arranged on the outer surface of the sealed adjusting cavity and is used for providing a therapeutic light source; and the adjusting channel is arranged along the central shaft and is used for injecting a substance into the sealed adjusting cavity to support the sealed adjusting cavity. The device can be unfolded along with the unfolding of the sealed adjusting cavity after entering the body, and a large-area therapeutic light source is provided; since the flexible light sources are arranged only at the surface of the support structure, i.e. distributed only at positions corresponding to the treatment area, loss of light sources along the path is avoided.
Description
Technical Field
The present disclosure relates generally to the field of photomedical technology, and in particular, to a photomedical device.
Background
The flexible light source can be used in various occasions, such as indoor illumination, photodynamic therapy and the like, due to the changeable shape. Photodynamic therapy is a method for treating diseases by directly utilizing light or utilizing the cooperation of light and medicines, and is applied to clinical treatment at present. There are two main ways of photodynamic therapy, one is direct light therapy, and the other is light therapy and drug (also called photosensitizer) synergistic therapy. Photodynamic therapy is favored because of the advantages of good selectivity, minimal invasion, good tolerance, simple operation and the like. The photodynamic therapy can be divided into in vivo therapy and in vitro therapy, the in vivo therapy comprises bladder cancer, throat cancer, bronchial cancer and the like, the light source of the in vivo therapy is mainly laser optical fiber, and the optical fiber has the advantages of easy insertion into the body and small wound. However, the light energy loss of the optical fiber is large, the uniformity of the light emission is poor, and the light energy irradiated to the focus through the optical fiber is low in the treatment process of a large organ, which is not favorable for photodynamic treatment.
Disclosure of Invention
In view of the above-mentioned deficiencies or inadequacies in the prior art, it would be desirable to provide a photomedical device comprising:
a central shaft;
the sealing adjusting cavity is wrapped at the end part of the central shaft;
the flexible light source is arranged on the outer surface of the sealed adjusting cavity and is used for providing a therapeutic light source;
and the adjusting channel is arranged along the central shaft and is used for injecting a substance into the sealed adjusting cavity to support the sealed adjusting cavity.
According to the technical scheme provided by the embodiment of the application, the adjusting channel is formed by an injection pipe fixed outside the central shaft, and the injection pipe extends into the sealing adjusting cavity.
According to the technical scheme provided by the embodiment of the application, the central shaft is hollow, wherein a hollow cavity body forms the adjusting channel; the central shaft is provided with a radial outlet corresponding to the sealing adjusting cavity.
According to the technical scheme provided by the embodiment of the application, the sealing adjusting cavity is formed by fixing a flexible substrate on the outer wall of the central shaft, and the flexible light source is fixedly attached to the surface of the flexible substrate.
According to the technical scheme provided by the embodiment of the application, the flexible light source is a flexible OLED which is in a fusiform sheet shape, and the edge of the flexible OLED is fixed on the flexible substrate.
According to the technical scheme provided by the embodiment of the application, a row of connecting ribs are fixed on the bottom surface of the substrate of the OLED in the direction perpendicular to the central axis.
According to the technical scheme provided by the embodiment of the application, the flexible light source comprises at least one of an OLED light source, an LED light source, a quantum point light source, a miniLED light source, a micro LED light source and an optical fiber, and a skin-friendly material layer is coated outside the flexible light source.
According to the technical scheme that this application embodiment provided, still include the lamp area, be fixed with on the lamp area flexible light source, the lamp area weave in sealed regulation chamber surface.
According to the technical scheme provided by the embodiment of the application, the substance is gas or liquid; preferably, the thermal conductivity of the liquid is 0.5W/(mK).
According to the technical scheme provided by the embodiment of the application, the central shaft is provided with sealed outwards-protruding adjusting cavities at two sides of the sealed adjusting cavity, and the sealed outwards-protruding adjusting cavities are provided with auxiliary adjusting channels for injecting substances into the outwards-protruding adjusting cavities to support the outwards-protruding adjusting cavities.
The device comprises a central shaft, a sealed adjusting cavity and a flexible light source arranged on the outer surface of the sealed adjusting cavity; the flexible light source on the sealing adjusting cavity can be contracted along with the contraction of the sealing adjusting cavity and expanded along with the expansion of the sealing adjusting cavity by injecting substances into the sealing adjusting cavity to support the sealing adjusting cavity, so that the device can conveniently enter a body in a small-volume structure and can be expanded along with the expansion of the sealing adjusting cavity after entering the body, and a large-area therapeutic light source is provided; since the flexible light sources are arranged only at the surface of the support structure, i.e. only distributed at positions corresponding to the treatment area, loss of light sources along the path is avoided.
Drawings
Other features, objects and advantages of the present application will become more apparent upon reading of the following detailed description of non-limiting embodiments thereof, made with reference to the accompanying drawings in which:
FIG. 1a is a schematic structural diagram of a first embodiment of example 1 of the present application;
FIG. 1b is a schematic structural diagram of a second embodiment of example 1 of the present application;
FIG. 2a is a schematic structural diagram of embodiment 2 of the present application;
FIG. 3a is a schematic structural diagram of a first arrangement of a flexible OLED in example 3 of the present application;
FIG. 3b is a schematic structural diagram of a second arrangement of a flexible OLED in example 3 of the present application;
fig. 4a is a schematic view of an unfolded structure of the woven lamp strip in embodiment 4 of the present application;
fig. 4b is a schematic cross-sectional structure view of the woven lamp strip in embodiment 4 of the present application;
FIG. 5a is a schematic structural diagram of a first operating state in embodiment 5 of the present application;
FIG. 5b is a schematic structural diagram illustrating a second operating state in embodiment 5 of the present application;
reference numbers in the figures:
10. a central shaft; 21. sealing the adjusting cavity; 30. a flexible light source; 20. a flexible substrate; 40. an injection pipe; 41. an injection pipe I; 42. an injection pipe II; 43. a planarization layer; 11. adjusting the channel; 31. a flexible OLED; 31-1. connecting ribs; 45. a light strip; 45-1, a transverse lamp strip; 45-2, longitudinal lamp band; 50. a convex adjusting cavity; 51. a convex adjusting cavity I; 52. and a convex adjusting cavity II.
Detailed Description
The present application will be described in further detail with reference to the following drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the relevant invention and not restrictive of the invention. It should be noted that, for convenience of description, only the portions related to the present invention are shown in the drawings.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to the embodiments with reference to the attached drawings.
Example 1
Referring to fig. 1, the present embodiment provides a photomedical device, including:
a central shaft 10;
a seal adjusting cavity 21 wrapped at the end of the central shaft 10;
the flexible light source 30 is arranged on the outer surface of the sealed adjusting cavity 21 and is used for providing a therapeutic light source;
and a regulating passage arranged along the central shaft 10 for injecting a substance into the sealed regulating cavity 21 to support it.
In the present embodiment, the central shaft 10 is made of steel wire, thin deformable plastic rod or tube, hollow or solid rubber tube; the end part of the sealed adjusting cavity 21 is used for extending into the body for treatment, and the other end is exposed out of the body.
In this embodiment, the sealed adjustment cavity 21 is formed by fixing a flexible substrate on the outer wall of the central shaft 10, and the flexible light source 30 is fixed on the surface of the flexible substrate 20.
The flexible substrate 20 can be made of rubber, PMDS, PTFE, fibroin, or other materials, and when the flexible light source is a sheet-like OLED, each sheet of OLED can be fixed on the surface of the flexible substrate by gluing; the fixed connection position of the flexible base material 20 and the central shaft is fixed in an ultrasonic welding, laser welding and electric welding mode, or is connected and sealed by adopting a sealant.
In some embodiments, a plurality of spliced sheet-shaped OLEDs can be used to directly form the sealed adjustment cavity 21, and the substrate of the OLED is made of organic polymer materials such as parylene, rubber, and nitrile.
Wherein the regulating channel is optionally formed in the following manner:
embodiment 1: as shown in fig. 1a, the adjustment channel is formed by an injection tube 40 fixed outside the central shaft 10, the injection tube 40 extending into the sealed adjustment chamber 21.
At this time, an opening is formed at one end of the injection pipe 40, which is far away from the sealed adjustment cavity 21, and air is injected into the sealed adjustment cavity 21 through the opening, at this time, preferably, an air pump connector is installed at the opening, and after an air outlet of the inflator pump is connected with the connector, the inflator pump is started to inflate the sealed adjustment cavity 21; in a further preferred embodiment, a pressure sensor is provided in the injection tube 40, and the air pump stops the inflation when the pressure sensor reaches a set pressure, so that the seal adjusting chamber 21 is in a state of constant pressure. Preferably, a valve which can be manually or electrically controlled to open and close is arranged in the injection pipe 40 and is used for disconnecting the injection pipe 40 from an air supply path of the inflator pump and stopping air supply when the pressure of the sealed adjusting cavity 21 reaches a set value; when the treatment is completed, the valve can be opened to release the gas in the sealed adjustment chamber 21.
After the treatment is finished, the opening of the injection tube 40 is deflated, so that the sealed adjusting cavity 21 is contracted, the volume is reduced, and the device can be taken out of the body.
In other embodiments, the gas may be replaced by a liquid and correspondingly the gas pump replaced by a water pump. At this time, it is preferable that the thermal conductivity of the liquid is > 0.5W/(m.K); for example, the physiological saline is convenient for cooling the light-emitting device through the circulation of the liquid, so that the working time of the device in the body is prolonged, and the working efficiency is improved. And avoid the pain caused by high temperature.
Embodiment 2: as shown in fig. 1b, the central shaft 10 is hollow, wherein the hollow body forms the regulating passage 11; the central shaft is provided with a radial outlet corresponding to the seal adjusting cavity 21.
At this time, the end of the central shaft 10 away from the seal adjustment chamber 21 is opened, and the using process is the same as that of embodiment 1, which is not described again.
In this embodiment, the color of the flexible light source may be red light, blue-green light or blue light, or a light source with multiple mixed colors:
the irradiation depth of the yellow green light with the wave band of 510 nm-590 nm is between the blue light and the red light, so that the dredging and the expansion of the capillary vessel in the skin depth can be promoted, the resistance of cells is enhanced, and the treatment effect of the affected part is accelerated.
Red light with a waveband of 590-810 nm can enable mitochondria to release cytochrome c oxidase, increase adenosine triphosphate, and enable cells to provide energy by utilizing the adenosine triphosphate, so that the metabolism of the cells is promoted; meanwhile, the red light irradiation heats molecules in the blood vessel, so as to adjust the blood vessel expansion and improve the blood circulation;
the blue light irradiation of the 440-510 nm wave band can be used for relieving pain and swelling caused by inflammation. Therefore, the present embodiment can achieve a plurality of different therapeutic effects by arranging different light sources.
The flexible light source can also be at least one of an OLED light source, an LED light source, a quantum dot light source, a miniLED light source, a microLED light source and an optical fiber or a combination of any two or three of the above.
In other embodiments, the flexible light source 40 is coated with a skin-friendly material layer, such as silica gel, Polydimethylsiloxane (PDMS), silica gel, Collagen (Collagen), Silicone Hydrogel (Hydrogel), Hydrogel (hydrocoloid), Polyurethane (PU), polymethyl methacrylate (PMMA), polymethylpentene polymer (PMP), Polyethylene (PE), polycarbonate, polystyrene, acrylonitrile butadiene styrene, polyolefin, polyamide, polyvinyl chloride, polyethylene, polypropylene, nylon, polyester, Silicone, polyimide, polytetrafluoroethylene, polyethersulfone, polysulfone, polyetheretherketone, chitosan, pectin, gelatin, nylon, fiber, and the like.
OLED light source, LED light source directly set up on bearing structure's surface, compare the mode of single fiber treatment among the prior art, have avoided the loss on the route.
When adopting flexible light source to lay on bearing structure's surface, compare the mode of single fiber treatment among the prior art, because when the treatment, bearing structure is expanded, can be close to the focus area more, avoids the loss that liquid leads to. For example, some lesions such as bladder may sometimes block the lesion due to larger organs, and the whole bladder may be supported by filling liquid during treatment, and light loss may also be caused due to the presence of liquid, especially for the case of a single light guide fiber, the liquid needs to be transmitted from the end of the fiber to the lesion, and in this case, the light loss may be very serious; and in the technical scheme of this application, strut through bearing structure for the light source can be close to focus position more, and the distance that light permeates through liquid is shorter, and correspondingly, light loss also can be a lot less.
When the photomedical device provided by the embodiment is used for in-vivo treatment, the supporting structure and the flexible light source can be sent into the body by pushing the central shaft. The photomedical device provided by the embodiment can also be used for extracorporeal treatment, and local treatment can be performed by selectively electrifying part of the flexible light source.
Example 2
On the basis of example 1, as shown in fig. 2a, in this example, the flexible light source is a flexible OLED31, which is in the form of a shuttle sheet, and the edge of which is fixed on the flexible substrate 20.
When the sealed adjusting cavity 21 is contracted, the flexible light source is folded along the central line, and the central shaft is rotated clockwise or anticlockwise at the moment, so that the folded flexible light source and the shuttle-shaped sheet can be curled; if the treatment is performed by clockwise curling, the flexible light source is turned on by rotating the central shaft 10 counterclockwise after entering the body.
In this embodiment, can curl flexible OLED through the rotation center pin during shrink, further reduce the volume of the entering end of this device, provide convenience for the use.
Example 3
In addition to embodiment 2, in this embodiment, as shown in fig. 3a, a row of connection ribs 31-1 is fixed on the bottom surface of the substrate of the flexible OLED31 in a direction perpendicular to the central axis.
Therefore, when the support structure is contracted, the folded part of the flexible OLED31 can avoid the damage of the flexible OLED31 caused by complete folding, and particularly, for a whole piece of OLED light source, the connecting rib 31-1 increases the bending angle.
In other embodiments, as shown in fig. 3b, the effect of the enlarged folding angle of the connecting ribs can also be achieved by providing a greater thickness in the middle of the flexible OLED31 substrate material along the length direction.
Example 4
As shown in fig. 4a and 4b, the present embodiment differs from embodiment 1 in that, based on embodiment 1: the fixing mode of the light source is changed into a flexible braided structure, and the flexible braided structure covers the outside of the flexible base material 20; the light source is fixed to a light strip, which in this embodiment, as shown in fig. 4a, comprises a transverse strip 45-1 and a longitudinal strip 45-2; the transverse strip 45-1 and the longitudinal strip 45-2 are woven on the supporting structure 30, and the transverse strip 45-1 and the longitudinal strip 45-2 may be made of thin rubber sheets, for example.
In this embodiment, the light sources are LED beads, which are connected in parallel or in series by a circuit, the horizontal light strip 45-1 and the vertical light strip 45-2 are provided with a flat layer 43 covering all the light sources 40, the flat layer is made of an organic material, such as PMMA, parylene, etc., and the thickness of the flat layer is 10 μm to 50 μm higher than that of the light sources. The flat layer 43 enables the lamp strip to be relatively flat, and improves comfort in use.
In other embodiments, the LED lamp beads can be replaced by optical fibers or OLED light sources, and the optical fibers are attached to the transverse lamp strip 45-1 and the longitudinal lamp strip 45-2 along the length direction;
because the lamps arranged at all positions of the lamp strip are independent individuals and have consistent luminous brightness, the luminous uniformity of the whole braided lamp strip is better compared with that of a massive whole flexible light source; because the light-emitting brightness of the large and integral flexible light source at the position far away from the bonding area is darker, and the light-emitting brightness of the position close to the bonding area is brighter.
Example 5
On the basis of embodiment 1, in this embodiment, a sealed outer convex adjusting cavity is arranged on the central shaft 10 on both sides of the sealed adjusting cavity 21, and a secondary adjusting channel is used for injecting a substance into the outer convex adjusting cavity to support the outer convex adjusting cavity.
Wherein the outwardly convex adjustment chamber 50 is also formed by the flexible substrate material surrounding. The outer convex regulating cavity near the end of the central shaft 10 is the outer convex regulating cavity I51, and the other outer convex regulating cavity is the outer convex regulating cavity II 52. The material is injected into the convex adjusting cavity I51 through an injection pipe I41, the material is injected into the convex adjusting cavity II52 through an injection pipe II42,
the outer convex adjusting cavity I51, the outer convex adjusting cavity II52 and the sealed adjusting cavity 21 are independently controlled to independently and freely realize contraction.
As shown in fig. 5a, when the optical medical device enters the body, the outer convex adjusting cavity I51 is injected with a substance and slightly expands, the outer convex adjusting cavity II52 and the sealed adjusting cavity 21 are evacuated and are in a contracted state, and a temporary space is expanded between the front end of the outer convex adjusting cavity I51 in the entering direction and skin tissue so as to avoid the direct contact of the flexible light source outside the sealed adjusting cavity 21 and the skin tissue and protect the flexible light source.
Accordingly, as shown in fig. 5b, when the optical medical device is taken out from the body, the outward convex adjusting cavity II52 is filled with the injected substance and slightly expands, the outward convex adjusting cavity I51 and the sealed adjusting cavity 21 are evacuated, and the outward convex adjusting cavity II52 is in a contracted state, and a temporary space is expanded between the front end of the entering direction and the skin tissue, so that the flexible light source outside the sealed adjusting cavity 21 is prevented from directly contacting the skin tissue, and the flexible light source can also be protected.
The above description is only a preferred embodiment of the application and is illustrative of the principles of the technology employed. It will be appreciated by a person skilled in the art that the scope of the invention as referred to in the present application is not limited to the embodiments with a specific combination of the above-mentioned features, but also covers other embodiments with any combination of the above-mentioned features or their equivalents without departing from the inventive concept. For example, the above features may be replaced with (but not limited to) features having similar functions disclosed in the present application.
Claims (10)
1. An photomedical device, comprising:
a central shaft;
the sealing adjusting cavity is wrapped at the end part of the central shaft;
the flexible light source is arranged on the outer surface of the sealed adjusting cavity and is used for providing a therapeutic light source;
and the adjusting channel is arranged along the central shaft and is used for injecting a substance into the sealed adjusting cavity to support the sealed adjusting cavity.
2. The photomedical device of claim 1, wherein the conditioning channel is formed by an infusion tube secured outside the central shaft, the infusion tube extending into the sealed conditioning chamber.
3. The photomedical device of claim 1, wherein the central shaft is hollow, wherein a hollow cavity forms the conditioning channel; the central shaft is provided with a radial outlet corresponding to the sealing adjusting cavity.
4. The photomedical device of claim 1, wherein the sealed, regulated cavity is formed by a flexible substrate secured to an outer wall of a central shaft, the flexible light source being secured to a surface of the flexible substrate.
5. The photomedical device of claim 4, wherein the flexible light source is a flexible OLED having its edges secured to the flexible substrate.
6. The photomedical device of claim 5, wherein the bottom surface of the substrate of the OLED has a connecting rib affixed to it in a direction perpendicular to the central axis.
7. The photomedical device of claim 1, wherein the flexible light source comprises at least one of an OLED light source, an LED light source, a quantum dot light source, a miniLED light source, a microLED light source, an optical fiber; the flexible light source is coated with a skin-friendly material layer.
8. The photomedical device of any of claims 1-4 and 7, wherein the substance is a gas or a liquid; preferably, the thermal conductivity of the liquid is 0.5W/(mK).
9. The photomedical device of any of claims 1-4 and 7, further comprising a light strip to which the flexible light source is affixed, the light strip being woven onto the outer surface of the sealed conditioning chamber.
10. The photomedical device of any one of claims 1-4, 7,
and the two sides of the sealed adjusting cavity on the central shaft are provided with sealed convex adjusting cavities, and the sealed convex adjusting cavities are provided with auxiliary adjusting channels for injecting substances into the convex adjusting cavities to support the convex adjusting cavities.
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CN202111026832.7A CN113599716A (en) | 2021-09-02 | 2021-09-02 | Optical medical device |
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CN202111026832.7A CN113599716A (en) | 2021-09-02 | 2021-09-02 | Optical medical device |
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