CN113598739A - Pipeline patency detection device and method - Google Patents
Pipeline patency detection device and method Download PDFInfo
- Publication number
- CN113598739A CN113598739A CN202111050176.4A CN202111050176A CN113598739A CN 113598739 A CN113598739 A CN 113598739A CN 202111050176 A CN202111050176 A CN 202111050176A CN 113598739 A CN113598739 A CN 113598739A
- Authority
- CN
- China
- Prior art keywords
- flow rate
- pipeline
- liquid
- patency
- wall
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000001514 detection method Methods 0.000 title claims abstract description 17
- 238000000034 method Methods 0.000 title abstract description 15
- 239000007788 liquid Substances 0.000 claims abstract description 149
- 230000036772 blood pressure Effects 0.000 claims abstract description 76
- 238000009530 blood pressure measurement Methods 0.000 claims abstract description 19
- 230000005611 electricity Effects 0.000 claims abstract 2
- 238000007789 sealing Methods 0.000 claims description 54
- 239000000523 sample Substances 0.000 claims description 16
- 239000013013 elastic material Substances 0.000 claims description 7
- 230000000149 penetrating effect Effects 0.000 claims description 7
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 238000012360 testing method Methods 0.000 claims description 2
- 238000001125 extrusion Methods 0.000 claims 1
- 230000008569 process Effects 0.000 abstract description 3
- 238000001802 infusion Methods 0.000 description 33
- 239000012530 fluid Substances 0.000 description 12
- 230000010412 perfusion Effects 0.000 description 8
- 238000010586 diagram Methods 0.000 description 7
- 208000007536 Thrombosis Diseases 0.000 description 5
- 206010001526 Air embolism Diseases 0.000 description 4
- 210000004204 blood vessel Anatomy 0.000 description 4
- 238000003825 pressing Methods 0.000 description 4
- 230000007704 transition Effects 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 238000004891 communication Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 230000008719 thickening Effects 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 206010008088 Cerebral artery embolism Diseases 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000004872 arterial blood pressure Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000013130 cardiovascular surgery Methods 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000035487 diastolic blood pressure Effects 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003978 infusion fluid Substances 0.000 description 1
- 201000010849 intracranial embolism Diseases 0.000 description 1
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229920002529 medical grade silicone Polymers 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012806 monitoring device Methods 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000035488 systolic blood pressure Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
- A61B5/02156—Calibration means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Physiology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Abstract
The application provides a pipeline patency detection device and method for detect the patency of invasive blood pressure measurement pipeline, including first connecting portion, velocity of flow control portion, second connecting portion, pressure sensing portion and blood pressure display device, first connecting portion, velocity of flow control portion, second connecting portion, pressure sensing portion have the liquid circulation passageway of intercommunication, pressure sensing portion includes the wire, the wire with blood pressure display device electricity is connected, flows through the liquid of velocity of flow control portion has first velocity of flow and second velocity of flow, just the second velocity of flow is greater than the first velocity of flow. The device and the method for detecting the patency of the pipeline can rapidly and accurately judge the patency of the pipeline of the invasive blood pressure measuring equipment in the process of measuring the invasive blood pressure of a patient.
Description
Technical Field
The application belongs to the invasive blood pressure measuring field, and particularly relates to an invasive blood pressure measuring pipeline patency detection device and a using method thereof.
Background
Invasive Blood Pressure (IBP) measurement is a method of directly measuring the Blood pressure in a Blood vessel after puncturing and placing the Blood vessel, can directly, continuously and dynamically monitor the real Blood pressure condition of a patient, and is widely applied in the field of emergency treatment, cardiovascular surgery, intensive care units and surgical anesthesia.
The principle of obtaining blood pressure by invasive blood pressure measurement is as follows: the Pressure sensor converts the intravascular Pressure into an electric signal and processes the electric signal to display Blood Pressure waveform and Blood Pressure values in a continuous and dynamic mode on a Blood Pressure display device such as a screen of an electrocardiogram monitor and the like, wherein the Blood Pressure waveform and the Blood Pressure values comprise Systolic Pressure (SBP), Diastolic Pressure (DBP), mean arterial Pressure and the like.
One of the complications of invasive blood pressure measurement is air embolism, which may enter the blood vessel of a human body and form air embolism if air bubbles are contained in a liquid circulation pipeline, and can enter the cerebral vessels in serious cases to cause cerebral embolism; in addition, the presence of air bubbles also affects the patency of the fluid line and further affects the accuracy of the blood pressure measurement, thus requiring the fluid flow line to be flushed through with the perfusate to evacuate the air bubbles prior to lancing.
In clinical application of invasive blood pressure measurement, even if bubbles in the liquid circulation pipeline are completely exhausted before puncture, a large amount of micro bubbles are generated and attached to the inner wall of the liquid circulation pipeline and gradually fused to form bubbles with larger volume and possibly further form air embolism as time goes on; in addition, thrombus formed at the tail end of a pipeline in a patient body may influence the accuracy of a blood pressure measurement result, so that the patency of a liquid pipeline needs to be detected frequently clinically to ensure the accuracy and the safety of the blood pressure measurement result, and a device capable of rapidly, accurately and visually detecting whether air bubbles, air embolism, thrombus and other factors influencing the patency of the pipeline exist in the invasive blood pressure measurement pipeline is needed.
Disclosure of Invention
The application aims to provide a pipeline patency detection device and a using method thereof, which are used for rapidly, accurately and visually detecting whether air bubbles exist in an invasive blood pressure measurement pipeline or not and other factors influencing the patency of the pipeline.
One aspect of the application provides a pipeline patency detection device for detecting patency of an invasive blood pressure measurement pipeline, comprising a first connection part, a flow rate control part, a second connection part, a pressure sensing part and a blood pressure display device, wherein the first connection part, the flow rate control part, the second connection part and the pressure sensing part are provided with communicated liquid circulation passages, the pressure sensing part comprises a lead, and the lead is electrically connected with the blood pressure display device; the liquid flowing through the flow rate control portion has a first flow rate and a second flow rate, and the second flow rate is greater than the first flow rate.
Preferably, the first flow rate is 2 to 4 ml/h and the second flow rate is 10 to 60 ml/min.
Further, the flow rate control part includes a micro-hole tube and a flow rate switching tube; the micropore pipe is a cylinder with micropores which are axially communicated at the radial center; the flow rate switching pipe comprises a hollow elastic round pipe, circular sealing parts arranged at two ends of the hollow elastic round pipe and a lifting part arranged at the upper part of the outer wall of the hollow elastic round pipe.
Further, the micro-hole pipe is made of a hard material, and the flow rate switching pipe is made of a soft elastic material; the hollow elastic round pipe is sleeved outside the microporous pipe in an interference fit manner; the annular sealing part is formed by extending two ends of the hollow elastic circular tube along the axial direction, and the diameter of the inner wall of the annular sealing part is larger than that of the outer wall of the microporous tube.
Furthermore, the first connecting part comprises a first liquid pipeline, an annular first sealing groove positioned at one end of the first liquid pipeline facing the flow rate control part, a first limiting part and a pipeline joint, and the diameter of the inner wall of the first liquid pipeline facing the flow rate control part is larger than that of the outer wall of the microporous pipe; the second connecting part comprises a second liquid pipeline, a circular second sealing groove and a second limiting part, wherein the circular second sealing groove is positioned at one end, facing the flow rate control part, of the second liquid pipeline, and the diameter of the inner wall, facing the flow rate control part, of the second liquid pipeline is larger than that of the outer wall of the microporous pipe; the first sealing groove and the second sealing groove are in sealing connection with the annular sealing part through interference fit, and the first limiting part is detachably connected with the second limiting part; the pressure sensing part further comprises a third liquid pipeline, the second connecting part is fixedly connected with the pressure sensing part, and the second liquid pipeline is communicated with the third liquid pipeline.
Preferably, the first liquid pipeline has a slot penetrating through the inner wall and the outer wall towards the upper part of one end of the flow rate control part; the second liquid pipeline is provided with a slot penetrating through the inner wall and the outer wall towards the upper part of one end of the flow rate control part; and non-through slots are formed in the upper parts of the inner walls of the two ends of the hollow elastic round pipe.
Preferably, the flow rate switching tube further comprises pressing pieces located at both sides of an upper portion of an outer wall of the flow rate switching tube.
Furthermore, the pressure sensing part also comprises a pressure sensing probe, a pressure sensor chip, a shell and a rear cover; the third liquid pipeline is provided with an opening for accommodating the pressure sensing probe, and the pressure sensing probe is arranged in the third liquid pipeline through the opening and is sealed and fixed; the pressure sensing chip is electrically connected with the pressure sensing probe and receives the liquid pressure data in the third liquid pipeline acquired by the pressure sensing probe, and the wire transmits the liquid pressure data acquired by the pressure sensing chip to the blood pressure display device.
Another aspect of the application provides a method for detecting the patency of an invasive blood pressure measurement pipeline by using the device for detecting the patency of the pipeline, which comprises the following steps:
a first step of pulling up the pulling portion for a certain time;
reading a liquid pressure waveform in a third liquid pipeline at the second flow rate from the blood pressure display device;
thirdly, loosening the lifting part;
fourthly, reading a liquid pressure waveform in a third liquid pipeline at the first flow rate from the blood pressure display device;
and fifthly, judging the patency of the pipeline of the invasive blood pressure measuring equipment according to the state of the conversion from the liquid pressure waveform at the second flow rate to the liquid pressure waveform at the first flow rate.
The embodiment of the application has at least the following beneficial effects:
the embodiment of the application comprises a flow rate control part, wherein the lifting part is lifted and released, so that liquid flowing through the flow rate control part and entering a third liquid pipeline has a first flow rate and a second flow rate which is larger than the first flow rate, the liquid pressure in the third liquid pipeline is consistent with the blood pressure at the tip of an intravascular catheter at the first flow rate, and the liquid pressure in the third liquid pipeline is consistent with the liquid pressure in a liquid conveying pipeline at one end of an infusion device at the second flow rate; the pressure sensing part acquires the liquid pressure in the third liquid pipeline and displays a pressure waveform on the blood pressure display device, when factors influencing the smoothness of the pipeline, such as bubbles, thrombus and the like exist in the infusion pipeline at the puncture end, the conversion time of recovering the pressure waveform at the second flow rate to the pressure waveform at the first flow rate is longer than that of the infusion pipeline at the puncture end in a good smoothness state, and the smoothness of the pipeline of the invasive blood pressure measuring equipment can be rapidly and accurately judged in the process of carrying out invasive blood pressure measurement on a patient through judgment of the conversion state of the pressure waveform on the blood pressure display device.
Drawings
FIG. 1 is a system framework of an invasive blood pressure measurement device according to an embodiment of the present application;
FIG. 2 is an enlarged view of a portion of an invasive blood pressure measuring device according to an embodiment of the present application;
FIG. 3 is a perspective view of a microporous tube according to an embodiment of the present application;
FIG. 4 is a perspective view of a microporous tube D-D cut away according to an embodiment of the present application;
FIG. 5 is a perspective view of a flow rate switching tube according to an embodiment of the present application;
FIG. 6 is a perspective view of a flow switching tube D-D cut away in an embodiment of the present application;
FIG. 7 is a schematic view of the assembly of the micro-bore tube and the flow rate switching tube according to the embodiment of the present application;
FIG. 8(a) is a plan view of a flow rate control section C-C cut along the line in the invasive blood pressure measuring state according to the embodiment of the present application;
FIG. 8(b) is a perspective view of the flow rate control part C-C cut away when the pulling part is lifted up in the patency detection state according to the embodiment of the present application;
fig. 9 is a perspective view of a first connection portion of an embodiment of the present application;
FIG. 10 is a perspective view of a first connector portion of an embodiment of the present application taken in a direction D-D;
FIG. 11 is a perspective view of a second connection portion of an embodiment of the present application;
FIG. 12 is a perspective view of a second connector portion of an embodiment of the present application taken along line D-D;
fig. 13 is an exploded view of the first connection portion, the flow control portion, the second connection portion, and the pressure sensing portion according to the embodiment of the present application;
FIG. 14 is a plan view taken in direction D-D of the first connecting portion, the flow rate control portion and the second connecting portion in an invasive blood pressure measuring state according to the embodiment of the present application;
FIG. 15 is a plan view, cut along direction D-D, of the first connecting portion, the flow rate control portion, and the second connecting portion 13 assembled when the pulling portion is lifted in the patency detection state according to the embodiment of the present application
FIG. 16 is an exploded view of a pressure sensing section of an embodiment of the present application;
FIG. 17 is a flow chart of a method of using the device for testing patency of a conduit according to an embodiment of the present application;
FIG. 18(a) is a schematic diagram illustrating a transition state of a pressure waveform in a pipeline open state according to an embodiment of the present application;
fig. 18(b) is a schematic diagram showing a transition state of a pressure waveform when factors affecting patency, such as air bubbles and thrombus, are present in the tube according to the embodiment of the present application.
Reference numerals in the figures
11 a first connection part, 111 a first liquid pipeline, 112 a first sealing groove, 113 a first limit part, 114 a pipeline joint, 12 a flow rate control part, 121 a micropore pipe, 1211 a micropore, 122 a flow rate switching pipe, 1221 a hollow elastic circular pipe, 1222 a circular sealing part, 1223 a pulling part, 1224 a squeezing sheet, 13 a second connection part, 131 a second liquid pipeline, 132 a second sealing groove, 133 a second limit part, 2 a pressure sensing part, 21 a third liquid pipeline, 22 an opening, 23 a pressure sensing probe, 24 a pressure sensor chip, 25 a rear cover, 26 a shell, 27 a lead wire, 3 a blood pressure display device, 4 an infusion pipeline, 5 an infusion set, 6 a pressurizable infusion bag, 7 a roller regulator, 8 a zero calibration three-way valve, 9 a three-way valve, 10 a puncture joint, 101 an intravascular catheter, a local amplification position A and a liquid circulation passage B.
Detailed Description
The present application is further described below in conjunction with the following figures based on preferred embodiments, and it is to be understood that the specific examples described herein are for purposes of illustration only and are not intended to limit the present application.
In addition, for convenience of understanding, various components on the drawings are enlarged (thick) or reduced (thin), but this is not intended to limit the scope of the present application.
Singular references also include plural references and vice versa.
In the description of the embodiments of the present application, it should be noted that if the terms "upper", "lower", "inner", "outer", etc. are used for indicating the orientation or positional relationship based on the orientation or positional relationship shown in the drawings or the orientation or positional relationship which is usually arranged when the embodiments of the present application are used, the description is only for convenience and simplicity, but the indication or suggestion that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and thus, cannot be understood as the limitation of the present application. Moreover, the terms first, second, etc. may be used in the description to distinguish between various elements, but these should not be limited by the order of manufacture or by importance to be understood as indicating or implying any particular importance, such as may be found in various claims.
The terminology used in the description is for the purpose of describing the embodiments of the application and is not intended to be limiting of the application. It is also to be understood that, unless otherwise expressly stated or limited, the terms "disposed," "connected," and "connected" are intended to be open-ended, i.e., may be fixedly connected, detachably connected, or integrally connected; they may be mechanically coupled, directly coupled, indirectly coupled through intervening media, or may be interconnected between two elements. The above-mentioned meanings specifically ascribed to the present application will be understood to those skilled in the art.
An aspect of the embodiments of the present application provides a tube patency detection apparatus for detecting patency of an invasive blood pressure measurement device tube, as shown in fig. 1 to 2, including:
the blood pressure monitoring device comprises a first connecting part 11, a flow rate control part 12, a second connecting part 13, a pressure sensing part 2 and a blood pressure display device 3, wherein the first connecting part 11, the flow rate control part 12, the second connecting part 13 and the pressure sensing part 2 are provided with communicated liquid circulation passages, the pressure sensing part 2 comprises a lead 27, and the lead 27 is electrically connected with the blood pressure display device 3; the liquid flowing through the flow rate control portion 12 has a first flow rate and a second flow rate, and the second flow rate is greater than the first flow rate.
Fig. 1 is an overall configuration device diagram of an invasive blood pressure measuring device provided with a tube patency detection apparatus according to the present embodiment, and fig. 2 is an enlarged view of a partially enlarged position a in fig. 1.
As shown in fig. 1 and 2, the device for detecting the patency of the pipeline comprises a first connecting part 11, a flow rate control part 12, a second connecting part 13, a pressure sensing part 2 and a blood pressure display device 3;
in this embodiment, a liquid flow path is provided between the first connection portion 11, the flow rate control portion 12, the second connection portion 13, and the pressure sensing portion 2, the first connection portion 11 is connected to the syringe 5 through the infusion pipeline 4, the syringe 5 is connected to the replaceable pressurizable infusion bag 6, the pressurizable infusion bag 6 is filled with infusion solution, the infusion pipeline between the syringe 5 and the first connection portion 11 is further provided with the roller adjuster 7, the pressure sensing portion 2 is connected to the zeroing three-way valve 8, and further is sequentially communicated with the three-way valve 9, the puncture connector 10 and the like through the infusion pipeline 4, the puncture connector 10 is connected to the intravascular catheter 101, so that a liquid flow path is formed by the invasive blood pressure measuring device from the pressurizable infusion bag 6 to the tip of the intravascular catheter 101, and the blood pressure at the tip of the intravascular catheter is the blood pressure to be measured, the infusion pipeline 4, the perfusion device 5, the perfusion bag 6, the roller regulator 7, the zero calibration three-way valve 8, the three-way valve 9, the puncture joint 10 and the intravascular catheter 101 are all standard components or common components known by the technicians in the field, and the structure and the principle of the components are known by the technicians in the field;
in the present embodiment, the liquid flowing through the flow rate control portion 12 has a first flow rate and a second flow rate, and the second flow rate is greater than the first flow rate.
Preferably, the first flow rate is 2 to 4 ml/h and the second flow rate is 10 to 60 ml/min.
Further, as shown in fig. 3 to 7, the flow rate control part 12 includes a micro-hole tube 121 and a flow rate switching tube 122; the micropore pipe 121 is a cylinder having micropores 1211 penetrating in the axial direction at the radial center; the flow rate switching tube 122 includes a hollow elastic circular tube 1221, annular sealing portions 1222 provided at both ends of the hollow elastic circular tube 1221, and a pulling portion 1223 provided at an upper portion of an outer wall of the hollow elastic circular tube 1221.
Further, the orifice tube 121 is made of a hard material, and the flow rate switching tube 122 is made of a soft elastic material; the hollow elastic round tube 1221 is wrapped outside the microporous tube 121 through interference fit; the annular sealing portion 1222 is formed by extending the two ends of the hollow elastic circular tube 1221 in the axial direction, and the diameter of the inner wall of the annular sealing portion 1222 is larger than the diameter of the outer wall of the microporous tube 121.
In this embodiment, the microporous tube 121 is a cylinder made of hard material such as glass for medical use, plastic for medical use, etc., and as shown in a perspective view of the microporous tube 121 of fig. 3 and a sectional perspective view of the microporous tube 121 taken in a direction D-D of fig. 4, a radial center thereof has micropores 1211 penetrating in an axial direction, and the pore size of the micropores 1211 is set such that a flow rate of liquid flowing through the micropores 1211 is 2 to 4 ml/hr.
In the present embodiment, the flow rate switching tube 122 is made of a soft polymer material having elasticity such as medical silicone, and as shown in a perspective view of the flow rate switching tube 122 in fig. 5 and a perspective view of the flow rate switching tube cut in a direction D-D in fig. 6, the flow rate switching tube 122 includes a hollow elastic circular tube 1221, an annular sealing portion 1222, and a pulling portion 1223, which are integrally formed.
Specifically, as shown in the schematic diagram of fig. 7 in which the microporous tube 121 is assembled with the flow rate switching tube 122 (where the flow rate switching tube 122 is cut along the direction D-D), the inner wall diameter of the hollow elastic circular tube 1221 is slightly smaller than the outer wall diameter of the microporous tube 121, and the hollow elastic circular tube 1221 is wrapped outside the microporous tube 121 by interference fit by using the elasticity of the hollow elastic circular tube 1221; the annular sealing part 1222 is formed by extending two ends of the hollow elastic round tube 1221 along the axial direction, the diameter of the outer wall of the annular sealing part 1222 is the same as that of the outer wall of the hollow elastic round tube 1221, and the diameter of the inner wall of the annular sealing part 1222 is larger than that of the outer wall of the microporous tube 121, so that a space which can be filled with liquid is formed between the inner wall of the annular sealing part 1222 and the outer wall of the microporous tube 121; the pulling portion 1223 is located at an upper portion of the outer wall of the hollow elastic circular tube 1221.
In a normal use state, as shown in a sectional plan view of the flow rate control portion 12 in the direction of C — C in fig. 8(a), the inner wall of the hollow elastic circular tube 1221 and the outer wall of the microporous tube 121 are sealed by interference fit; when the pulling portion 1223 is pulled up, as shown in a C-C cut plan view of the flow rate control portion 12 in fig. 8(B), since the flow rate switching tube 122 is made of a soft elastic material, the elastic hollow elastic circular tube 1221 is pulled up and slightly deformed, and a liquid flow path B is formed between the inner wall of the hollow elastic circular tube 1221 and the outer wall of the microporous tube 121.
Further, the first connection portion 11 includes a first liquid pipeline 111, an annular first sealing groove 112 located at an end of the first liquid pipeline facing the flow rate control portion 12, a first limiting portion 113, and a pipeline joint 114, and a diameter of an inner wall of the first liquid pipeline 111 facing the flow rate control portion 12 is larger than a diameter of an outer wall of the microporous tube 121; the second connection portion 13 includes a second liquid pipeline 131, an annular second sealing groove 132 located at one end of the second liquid pipeline facing the flow rate control portion 12, and a second limiting portion 133, and the diameter of the inner wall of the second liquid pipeline 131 facing the flow rate control portion 12 is greater than the diameter of the outer wall of the microporous tube 121; the first sealing groove 112 and the second sealing groove 132 are in sealing connection with the annular sealing part 1222 through interference fit, and the first limiting part 113 is detachably connected with the second limiting part 133; the pressure sensing part 2 further comprises a third liquid pipeline 21, the second connecting part 13 is fixedly connected with the pressure sensing part 2, and the second liquid pipeline 131 is communicated with the third liquid pipeline 21.
In the present embodiment, as shown in the perspective view of the first connection portion 11 of fig. 9 and the cut-away perspective view of the first connection portion 11 in the direction D-D of fig. 10, the first connection portion 11 includes the first liquid pipe 111, and the diameter of the inner wall of the first liquid pipe 111 at the end facing the flow rate control portion 12 is set larger than the diameter of the outer wall of the microporous tube 121; a pipeline joint 114 is arranged at one end of the first liquid pipeline facing the perfusion apparatus, the pipeline joint 114 can be a standard joint such as a luer joint, and is connected with the perfusion apparatus 5 and the pressurizable infusion bag 6 through the infusion pipeline 4 (the infusion pipeline 4, the perfusion apparatus 5 and the pressurizable infusion bag 6 are not shown in the figure); a first sealing groove 112 is further formed in one end, facing the flow rate control portion 12, of the first connecting portion 11, the first sealing groove 112 is an annular groove surrounding the first liquid pipeline 111, and is formed by radially thickening a pipe wall of the first liquid pipeline 111 and axially extending the pipe wall in an annular groove form; the lower portion of the first connecting portion 11 is further provided with a first limiting portion 113.
In this embodiment, as shown in the perspective view of the second connection portion 13 in fig. 11 and the D-D cut perspective view of the second connection portion 13 in fig. 12, the second connection portion 13 includes a second liquid pipeline 131, the pressure sensing portion includes a third liquid pipeline 21, the second connection portion 13 is fixedly connected to the pressure sensing portion 2 by gluing or integral molding, and the second liquid pipeline 131 is communicated with the third liquid pipeline 21 and further connected to the zeroing three-way valve 8, the three-way valve 9, and the puncture connector 10 through the infusion pipeline 4 (the infusion pipeline 4, the three-way valve 9, and the puncture connector 10 are not shown); the diameter of the inner wall of the second liquid pipe 131 toward the end of the flow rate control part 12 is set larger than the diameter of the outer wall of the microporous tube 121; a second sealing groove 132 is further formed in one end, facing the flow rate control portion 12, of the second connecting portion 13, the second sealing groove 132 is an annular groove surrounding the second liquid pipeline 131, and is formed by radially thickening a pipe wall of the second liquid pipeline 131 and axially extending the pipe wall in the form of an annular groove; the second connecting portion 13 is further provided at a lower portion thereof with a second stopper 133.
The flow of the liquid through the first connection portion 11, the flow rate control portion 12, the second connection portion 13, and the pressure sensor 2 when the lifting portion 1223 is lifted in the invasive blood pressure measurement state and the patency detection state will be described in detail below with reference to fig. 13 to 15.
Fig. 13 shows an explosion diagram of the assembly of the first connection portion 11, the flow rate control portion 12, the second connection portion 13, and the pressure sensing portion 2, as shown in fig. 13, since the flow rate switching tube 122 is made of a soft elastic material, the annular sealing portion 1222 can enter the first sealing groove 112 and the second sealing groove 132 (not shown in the figure), and form a sealing connection through interference fit, the first limiting portion 113 and the second limiting portion 133 are detachably connected and fixed in a limiting manner by means of plugging or the like, so that the first connection portion 11, the flow rate control portion 12, and the second connection portion 13 are hermetically connected and fixed.
Fig. 14 is a sectional plan view of the first connection part 11, the flow rate control part 12, and the second connection part 13 assembled in a state of invasive blood pressure measurement, taken along line D-D, as shown in fig. 14, under the normal use condition of the invasive blood pressure measuring device, because the first sealing groove 112 and the second sealing groove 132 are hermetically connected with the annular sealing part 1222 (the overlapped part of the cross section in the figure is the interference fit and the sealing connection part), and the inner wall of the hollow elastic round tube 1221 is wrapped around the outer wall of the microporous tube 121 to form a seal, so that the perfusion fluid in the pressurizable infusion bag 6 can only flow through the micropores 1211 at a first flow rate after passing through the first fluid pipeline 111, and after sequentially flowing through the second liquid pipeline 131 and the third liquid pipeline 21, the liquid is communicated with the tip end of the intravascular catheter 101 through the infusion pipeline 4, due to the fluid pressure transfer, the fluid pressure in the third fluid line 21 now coincides with the blood pressure at the tip of the intravascular catheter 101.
Fig. 15 shows a D-D sectional plan view of the assembly of the first connection portion 11, the flow rate control portion 12, and the second connection portion 13 when the lifting portion 1223 is lifted in the patency detection state, as shown in fig. 15, when the lifting portion 1223 is lifted, because the flow rate switching tube 122 is made of a soft elastic material, the hollow elastic circular tube 1221 will be pulled upward and slightly deformed, so that a liquid flow path B is formed between the inner wall of the hollow elastic circular tube 1221 and the outer wall of the microporous tube 121, the perfusate flows through the flow rate control portion 12 at a second flow rate greater than the first flow rate and flows through the second liquid line 131 and the third liquid line 21 in sequence, at this time, because the flow rate of the perfusate increases, a new pressure balance is formed between the perfusate in the third liquid line 21 and the perfusate in the infusion line 4 at one end of the syringe 5, at this time, the liquid pressure in the third liquid line 21 is kept consistent with the liquid pressure in the infusion line 4 at one end of the syringe 5, and is greater than the blood pressure in the blood vessel at the puncture site.
Preferably, an upper portion of the first liquid pipe 111 toward one end of the flow rate control part 12 has a groove penetrating through an inner wall and an outer wall; the upper portion of the second liquid pipe 131 facing one end of the flow rate control part 12 has a slot penetrating the inner wall and the outer wall; the upper parts of the inner walls of the two ends of the hollow elastic round tube 1221 are provided with non-through slots.
In the present embodiment, by providing the above-mentioned slot, the liquid flow path between the first connection portion 11, the second connection portion 13 and the flow rate control portion 12 is expanded, so as to avoid blocking the liquid flow path in the case that the microporous tube 121 may move axially.
Preferably, the flow rate switching tube further includes pressing pieces 1224 at both sides of an upper portion of an outer wall of the flow rate switching tube.
In this embodiment, the pressing pieces 1224 are symmetrically disposed on two sides of the upper portion of the outer wall of the flow rate switching tube 122, when the pressing pieces 1224 are pinched from two sides to be pressed toward the middle, the hollow elastic circular tube 1221 is deformed more greatly, and a larger gap is formed between the inner wall of the hollow elastic circular tube and the outer wall of the microporous tube 121, so that the perfusate passing through the flow rate control part 12 has a third flow rate greater than the second flow rate, and the perfusate passing through the flow rate control part 12 at the third flow rate can be used to clean the invasive blood pressure measuring tube before puncturing and to remove air bubbles in the tube in advance.
Further, as shown in the exploded view of the pressure sensing section 2 of fig. 16, the pressure sensing section 2 further includes a pressure sensing probe 23, a pressure sensor chip 24, a back cover 25, and a housing 26; the third liquid pipeline 21 is provided with an opening 22 for accommodating a pressure sensing probe 23, and the pressure sensing probe 23 is arranged in the third liquid pipeline 21 through the opening 22 and is fixed in a sealing way; the pressure sensing chip 24 is electrically connected with the pressure sensing probe 23 and receives the liquid pressure data in the third liquid pipeline 21 acquired by the pressure sensing probe 23, and the lead 27 transmits the liquid pressure data acquired by the pressure sensing chip 24 to the blood pressure display device 3 and supplies power to the pressure sensing chip 24.
In this embodiment, the pressure sensing unit 2 and the blood pressure display unit 3 are both conventional modules constituting an invasive blood pressure measuring device, and the structure and principle thereof are well known to those skilled in the art and will not be described herein again.
Another aspect of the embodiments of the present application also provides a use method of the above-mentioned device for detecting patency of a tube of an invasive blood pressure measuring apparatus. The use method will be described in detail below with reference to fig. 17 to 18 (b).
It should be noted that, when the invasive blood pressure measuring apparatus is in a normal use state, because the first sealing groove 112 and the second sealing groove 132 are in sealing connection with the annular sealing portion 1222, and the inner wall of the hollow elastic circular tube 1221 is wrapped around the outer wall of the microporous tube 121 to form a seal, the perfusion fluid in the pressurizable infusion bag 6 can only flow through the micropores 1211 at a first flow rate after passing through the first liquid tube 111, and sequentially flow through the second liquid tube 131 and the third liquid tube 21, and form a liquid communication with the tip of the intravascular catheter 101 through the infusion tube 4, due to the liquid pressure transmission effect, the liquid pressure in the third liquid tube 21 is kept consistent with the blood pressure at the tip of the intravascular catheter 101, and the pressure sensing portion 2 obtains and displays the liquid pressure waveform on the blood pressure display device 3, that is, i.e., the blood pressure waveform at the tip of the intravascular catheter 101.
As shown in fig. 17, when performing the detection of the patency of the invasive blood pressure measurement tube, the using method of the tube patency detection apparatus includes the following steps:
s1: and pulling the pulling part upwards for a certain time.
Specifically, since the flow rate switching tube 122 is made of a soft elastic material, the hollow elastic circular tube 1221 is pulled upward and slightly deformed, so that a liquid flow path is formed between the inner wall of the hollow elastic circular tube 1221 and the outer wall of the microporous tube 121, the perfusate flows through the flow rate control unit 12 at a second flow rate greater than the first flow rate, and flows through the second liquid line 131 and the third liquid line 21 in sequence, and as the flow rate of the perfusate increases, the perfusate in the third liquid line 21 and the perfusate in the infusion line at one end of the syringe form a new pressure balance, and at this time, the liquid pressure in the third liquid line 21 and the liquid pressure in the infusion line 4 at one end of the syringe 5 are kept consistent and are greater than the blood pressure at the tip of the intravascular catheter 101.
S2: reading a fluid pressure waveform in a third fluid line at the second flow rate from the blood pressure display device.
Specifically, the pressure intensity obtained and converted by the pressure sensing part 2 and displayed on the blood pressure display device 3 is greater than the blood pressure at the tip of the intravascular catheter 101, and the pressure waveform displayed by the blood pressure display device 3 is in a step-like rising form.
S3: releasing the pull-up portion.
Specifically, the inner wall of the hollow elastic circular tube 1221 and the outer wall of the microporous tube 121 are sealed again, the perfusate flows through the flow rate control part again at the first flow rate, sequentially flows through the second liquid pipeline 131 and the third liquid pipeline 21, and then forms liquid communication with the tip of the intravascular catheter through the infusion pipeline, and due to the liquid pressure transmission effect, the liquid pressure in the third liquid pipeline 21 is kept consistent with the blood pressure at the tip of the intravascular catheter 101 again.
S4: reading a fluid pressure waveform in a third fluid line at the first flow rate from the blood pressure display device.
Specifically, the pressure obtained and converted by the pressure sensing part 2 and displayed on the blood pressure display device 3 changes to the blood pressure at the tip of the intravascular catheter 101 again, and the pressure waveform displayed by the blood pressure display device 3 shows a form of descending from a step-like high pressure and then changing to a periodic change.
S5: and judging the patency of the pipeline of the invasive blood pressure measuring equipment according to the state of the liquid pressure waveform at the second flow rate converted into the liquid pressure waveform at the first flow rate.
Fig. 18(a) shows a waveform transition diagram of the liquid pressure displayed on the blood pressure display device 3 when the infusion line 4 of the invasive blood pressure measuring apparatus maintains good patency, and fig. 18(b) shows a waveform transition diagram of the liquid pressure when there are factors in the infusion line on the puncture adapter 10 side that affect the patency of the line, such as air bubbles and thrombi.
Specifically, when the infusion line 4 maintains good patency, the above-mentioned steps S1 to S4 are executed, the liquid pressure in the third liquid line 21 is rapidly changed from keeping consistent with the liquid pressure in the infusion line 4 at one end of the perfusion apparatus to keeping consistent with the blood pressure at the tip of the intravascular catheter 101, correspondingly, the waveform displayed on the blood pressure display device 3 presents a steep falling edge, and then the periodically changing blood pressure waveform is recovered; when air bubbles and thrombus exist in the infusion pipeline 4 on one side of the puncture joint, the smoothness of the invasive blood pressure measuring pipeline is influenced, so that the pressure transmission time is prolonged, correspondingly, the time for restoring the liquid pressure in the third liquid pipeline 21 to be consistent with the blood pressure at the tip of the intravascular catheter 101 is prolonged, the waveform displayed on the blood pressure display device 3 presents a slow falling edge, and then the periodically changed blood pressure waveform is restored. And judging the patency of the invasive blood pressure measuring pipeline by analyzing the state of the conversion from the liquid pressure waveform at the second flow rate to the liquid pressure waveform at the first flow rate.
While the present invention has been described in detail and with reference to specific embodiments thereof, it will be apparent to one skilled in the art that various changes and modifications can be made therein without departing from the spirit and scope thereof as defined in the appended claims.
Claims (9)
1. The utility model provides a pipeline patency detection device for detect the patency of invasive blood pressure measurement pipeline, including first connecting portion, flow rate control portion, second connecting portion, pressure sensing portion and blood pressure display device, first connecting portion, flow rate control portion, second connecting portion, pressure sensing portion have the liquid circulation passageway of intercommunication, pressure sensing portion includes the wire, the wire with blood pressure display device electricity is connected, its characterized in that: the liquid flowing through the flow rate control portion has a first flow rate and a second flow rate, and the second flow rate is greater than the first flow rate.
2. The device for testing the patency of a conduit according to claim 1, wherein the first flow rate is 2 to 4 ml/hr and the second flow rate is 10 to 60 ml/min.
3. The pipeline patency detection device of claim 2, wherein:
the flow rate control part comprises a micropore pipe and a flow rate switching pipe;
the micropore pipe is a cylinder with micropores which are axially communicated at the radial center;
the flow rate switching pipe comprises a hollow elastic round pipe, circular sealing parts arranged at two ends of the hollow elastic round pipe and a lifting part arranged at the upper part of the outer wall of the hollow elastic round pipe.
4. The device for detecting the patency of the pipeline according to claim 3, wherein:
the micropore pipe is made of a hard material, and the flow speed switching pipe is made of a soft elastic material;
the hollow elastic round pipe is sleeved outside the microporous pipe in an interference fit manner;
the annular sealing part is formed by extending two ends of the hollow elastic circular tube along the axial direction, and the diameter of the inner wall of the annular sealing part is larger than that of the outer wall of the microporous tube.
5. The device for detecting the patency of the pipeline according to claim 4, wherein:
the first connecting part comprises a first liquid pipeline, an annular first sealing groove positioned at one end of the first liquid pipeline facing the flow rate control part, a first limiting part and a pipeline joint, and the diameter of the inner wall of the first liquid pipeline facing the flow rate control part is larger than that of the outer wall of the microporous pipe;
the second connecting part comprises a second liquid pipeline, a circular second sealing groove and a second limiting part, wherein the circular second sealing groove is positioned at one end, facing the flow rate control part, of the second liquid pipeline, and the diameter of the inner wall, facing the flow rate control part, of the second liquid pipeline is larger than that of the outer wall of the microporous pipe;
the first sealing groove and the second sealing groove are in sealing connection with the annular sealing part through interference fit, and the first limiting part is detachably connected with the second limiting part;
the pressure sensing part further comprises a third liquid pipeline, the second connecting part is fixedly connected with the pressure sensing part, and the second liquid pipeline is communicated with the third liquid pipeline.
6. The device for detecting the patency of the pipeline according to claim 5, wherein:
the upper part of one end of the first liquid pipeline, which faces the flow rate control part, is provided with a slot which penetrates through the inner wall and the outer wall;
the second liquid pipeline is provided with a slot penetrating through the inner wall and the outer wall towards the upper part of one end of the flow rate control part;
and non-through slots are formed in the upper parts of the inner walls of the two ends of the hollow elastic round pipe.
7. The device for detecting the patency of the pipeline according to claim 6, wherein:
the flow rate switching tube further comprises extrusion sheets positioned on two sides of the upper part of the outer wall of the flow rate switching tube.
8. The apparatus for detecting patency of pipeline according to any one of claims 5-7, wherein:
the pressure sensing part also comprises a pressure sensing probe, a pressure sensor chip, a shell and a rear cover;
the third liquid pipeline is provided with an opening for accommodating the pressure sensing probe, and the pressure sensing probe is arranged in the third liquid pipeline through the opening and is sealed and fixed;
the pressure sensing chip is electrically connected with the pressure sensing probe and receives the liquid pressure data in the third liquid pipeline acquired by the pressure sensing probe, and the wire transmits the liquid pressure data acquired by the pressure sensing chip to the blood pressure display device.
9. Use of a tube patency detection device according to any of claims 1-8 for detecting patency of an invasive blood pressure measurement tube, comprising the steps of:
a first step of pulling up the pulling portion for a certain time;
reading a liquid pressure waveform in a third liquid pipeline at the second flow rate from the blood pressure display device;
thirdly, loosening the lifting part;
fourthly, reading a liquid pressure waveform in a third liquid pipeline at the first flow rate from the blood pressure display device;
and fifthly, judging the patency of the pipeline of the invasive blood pressure measuring equipment according to the state of the conversion from the liquid pressure waveform at the second flow rate to the liquid pressure waveform at the first flow rate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111050176.4A CN113598739A (en) | 2021-09-08 | 2021-09-08 | Pipeline patency detection device and method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111050176.4A CN113598739A (en) | 2021-09-08 | 2021-09-08 | Pipeline patency detection device and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113598739A true CN113598739A (en) | 2021-11-05 |
Family
ID=78310146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111050176.4A Pending CN113598739A (en) | 2021-09-08 | 2021-09-08 | Pipeline patency detection device and method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113598739A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0331526A1 (en) * | 1988-03-04 | 1989-09-06 | Spectramed, Inc. | Improved flush-valve assembly for blood pressure measurement catheter |
| US4934375A (en) * | 1988-03-04 | 1990-06-19 | Spectramed, Inc. | Flush-valve assembly for blood pressure measurement catheter |
| US20130092256A1 (en) * | 2011-10-14 | 2013-04-18 | Horiba Stec, Co., Ltd. | Flow rate control device, diagnostic device for use in flow rate measuring mechanism or for use in flow rate control device including the flow rate measuring mechanism and recording medium having diagnostic program recorded thereon for use in the same |
| CN113598738A (en) * | 2021-09-08 | 2021-11-05 | 山东柏新医疗制品有限公司 | Flow velocity adjusting device and invasive blood pressure measuring equipment |
| CN215534337U (en) * | 2021-09-08 | 2022-01-18 | 山东柏新医疗制品有限公司 | Flow velocity adjusting device and invasive blood pressure measuring equipment |
| CN215687804U (en) * | 2021-09-08 | 2022-02-01 | 山东柏新医疗制品有限公司 | Perfusion valve of invasive blood pressure measurement pipeline |
| CN216060487U (en) * | 2021-09-08 | 2022-03-18 | 山东柏新医疗制品有限公司 | Pipeline patency detection device |
-
2021
- 2021-09-08 CN CN202111050176.4A patent/CN113598739A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0331526A1 (en) * | 1988-03-04 | 1989-09-06 | Spectramed, Inc. | Improved flush-valve assembly for blood pressure measurement catheter |
| US4934375A (en) * | 1988-03-04 | 1990-06-19 | Spectramed, Inc. | Flush-valve assembly for blood pressure measurement catheter |
| US20130092256A1 (en) * | 2011-10-14 | 2013-04-18 | Horiba Stec, Co., Ltd. | Flow rate control device, diagnostic device for use in flow rate measuring mechanism or for use in flow rate control device including the flow rate measuring mechanism and recording medium having diagnostic program recorded thereon for use in the same |
| CN113598738A (en) * | 2021-09-08 | 2021-11-05 | 山东柏新医疗制品有限公司 | Flow velocity adjusting device and invasive blood pressure measuring equipment |
| CN215534337U (en) * | 2021-09-08 | 2022-01-18 | 山东柏新医疗制品有限公司 | Flow velocity adjusting device and invasive blood pressure measuring equipment |
| CN215687804U (en) * | 2021-09-08 | 2022-02-01 | 山东柏新医疗制品有限公司 | Perfusion valve of invasive blood pressure measurement pipeline |
| CN216060487U (en) * | 2021-09-08 | 2022-03-18 | 山东柏新医疗制品有限公司 | Pipeline patency detection device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP3881037B2 (en) | Pressure transducer device with disposable dome | |
| US11969248B2 (en) | Catheter for monitoring pressure | |
| CN110996764B (en) | Catheter for monitoring intra-abdominal pressure | |
| US5993395A (en) | Pressure transducer apparatus with disposable dome | |
| JP2020522330A (en) | Catheter for monitoring uterine contraction pressure | |
| US7618370B2 (en) | Venous-arterial detector and pressure indicator | |
| US3720201A (en) | Disposable body fluid pressure monitor | |
| CA2115712A1 (en) | Intrauterine pressure catheter system | |
| CN216060487U (en) | Pipeline patency detection device | |
| EP2598015B1 (en) | Endoscopic pressure detection assembly | |
| CN215687804U (en) | Perfusion valve of invasive blood pressure measurement pipeline | |
| CN110448284A (en) | Invasive pressure sensor | |
| CN215534337U (en) | Flow velocity adjusting device and invasive blood pressure measuring equipment | |
| CN113598738A (en) | Flow velocity adjusting device and invasive blood pressure measuring equipment | |
| CN113598739A (en) | Pipeline patency detection device and method | |
| JP6472487B2 (en) | Steel tube with measuring element | |
| CN211324988U (en) | Invasive pressure sensor | |
| CN211460194U (en) | Pressure testing assembly and invasive pressure sensor | |
| CN110623650B (en) | Flush valve assembly and invasive pressure sensor | |
| CN114027815A (en) | Pressure detection device for abdominal high-pressure patient | |
| CN211834371U (en) | Pressure real-time monitoring device | |
| CN113273983A (en) | Novel invasive blood pressure monitoring system | |
| CN110448286A (en) | Invasive pressure sensor | |
| CN219803701U (en) | Arterial blood pressure and blood gas monitoring device | |
| CN219353894U (en) | Central venous pressure step sensor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |