CN113580649A - Tabletting equipment is used in production of metformin hydrochloride sustained-release tablet convenient to thresh - Google Patents

Tabletting equipment is used in production of metformin hydrochloride sustained-release tablet convenient to thresh Download PDF

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Publication number
CN113580649A
CN113580649A CN202110818721.3A CN202110818721A CN113580649A CN 113580649 A CN113580649 A CN 113580649A CN 202110818721 A CN202110818721 A CN 202110818721A CN 113580649 A CN113580649 A CN 113580649A
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CN
China
Prior art keywords
punch
metformin hydrochloride
fixedly connected
tablet
stamping
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN202110818721.3A
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Chinese (zh)
Inventor
林康
林峰
陈静
王广霞
刘梅芝
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Xiangrui Pharmaceutical Co ltd
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Jiangsu Xiangrui Pharmaceutical Co ltd
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Application filed by Jiangsu Xiangrui Pharmaceutical Co ltd filed Critical Jiangsu Xiangrui Pharmaceutical Co ltd
Priority to CN202110818721.3A priority Critical patent/CN113580649A/en
Publication of CN113580649A publication Critical patent/CN113580649A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B15/00Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/32Discharging presses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B30PRESSES
    • B30BPRESSES IN GENERAL
    • B30B11/00Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to the technical field of medicine production, in particular to tabletting equipment for producing a metformin hydrochloride sustained-release tablet convenient to thresh, which comprises a tabletting machine, wherein the tabletting machine is connected with a stamping structure for stamping metformin hydrochloride particles into tablets, the stamping structure is provided with an air compression structure for air injection, the stamping structure is connected with a compression structure for pressurizing the air compression structure, and the stamping structure is provided with a touch structure for touching the opening and closing structure to work; can be with the quick punching press of metformin hydrochloride granule into the tablet through stamping structure, under the cooperation through compressing air structure and compression structure, be convenient for jet-propelled the breaking away from with higher speed of tablet, under the cooperation of opening and closing structure and touch the structure, when the metformin hydrochloride slowly-releasing piece that has pressed breaks away from, jet-propelled the tablet to be convenient for the tablet breaks away from fast from stamping structure, avoid tablet bonding and stamping structure to bond and lead to the damage, improve the quality of tablet.

Description

Tabletting equipment is used in production of metformin hydrochloride sustained-release tablet convenient to thresh
Technical Field
The invention relates to the technical field of medicine production, in particular to tabletting equipment for producing a metformin hydrochloride sustained-release tablet convenient to thresh.
Background
The dosage forms of the medicines are various as follows: the production method of the powder, the tablet, the granule, the capsule, the solution, the emulsion, the suspension and the like is different according to different dosage forms, in the production process of the metformin hydrochloride sustained release tablet, the metformin hydrochloride is required to be mixed with auxiliary materials such as a disintegrant, a sustained release agent and the like to be prepared into powder or granules, then a tablet machine is used for tabletting, and in order to facilitate the degranulation of the tablet machine, tabletting equipment for producing the metformin hydrochloride sustained release tablet, which is convenient for degranulation, is required.
At present, the tabletting equipment for producing the metformin hydrochloride sustained-release tablets is a rotary disc type tabletting machine generally, in the tabletting process, tablets are easy to be bonded with the upper surface of a lower punch, when a scraper of the tabletting machine scrapes off, the bonding part of the tablets and the lower punch is easy to break, and the broken tablets do not accord with the production standard, so that the efficiency of medicine production is influenced.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides tabletting equipment for producing the metformin hydrochloride sustained-release tablets convenient for threshing.
The technical scheme adopted by the invention for solving the technical problems is as follows: the utility model provides a tablet pressing equipment is used in production of metformin hydrochloride sustained-release tablet convenient to thresh, includes the tablet press, the tablet press is connected with the stamping structure that is used for punching into the tablet with the metformin hydrochloride granule, stamping structure installs and is used for the jet-propelled structure of calming anger, stamping structure is connected with and is used for carrying out the compression structure that pressurizes to the structure of calming anger, stamping structure installs the opening and closing structure that is used for controlling the gas flow, stamping structure installs and is used for touching the structure of opening and closing and carry out the structure that touches of work.
Specifically, the stamping structure includes the upper punch, the tablet press is connected with the upper punch in a rotating manner, the tablet press is connected with the die in a rotating manner, the upper punch is connected with the die in a sliding manner, the tablet press is connected with the lower punch in a rotating manner, and the die is connected with the lower punch in a sliding manner.
Specifically, the structure of calming anger includes the third spring, down punch inside fixedly connected with third spring, the other end fixedly connected with backup pad of third spring, the top fixedly connected with gasbag of backup pad, the gasbag is cylindrical, the backup pad is the cake form.
Specifically, compression structure includes the clamp plate, the top fixedly connected with clamp plate of gasbag, the both ends fixedly connected with depression bar of clamp plate, be equipped with a pair of second spout on the depression bar, the depression bar passes through second spout and lower punching sliding connection, lower punching sliding connection has the clamping ring, and is a pair of depression bar and clamping ring fixed connection, the clamp plate is the cake form, the depression bar is "L" shape.
Specifically, the switching structure includes the air chamber, down the inside air chamber that is equipped with of punching, down the inside fixedly connected with trachea of punching, tracheal one end and air chamber intercommunication, the trachea other end runs through in the inside intercommunication of clamp plate and gasbag, down the inside fixedly connected with second spring of punching, the top fixedly connected with rubber buffer of second spring, the top and the lower conflict of rubber buffer, the air chamber passes through rubber buffer and outside intercommunication, the air chamber is cylindricly, the trachea is the heliciform.
The utility model discloses a structure, it includes the trigger piece to touch the structure, the inside sliding connection of undershoot has the trigger piece, the top fixedly connected with rubber circle of undershoot, the top and the rubber circle sliding connection of trigger piece, the bottom of trigger piece is contradicted with the top of rubber buffer, the both ends fixedly connected with trigger rod of trigger piece, trigger rod and undershoot sliding connection, the trigger rod cup jointed the sealing washer and with sealing washer sliding connection, sealing washer and undershoot fixed connection, the undershoot has cup jointed the touch ring, touch ring and trigger rod fixed connection, the die is equipped with first spout, the touch ring is through first spout and die sliding connection, the trigger rod is "L" shape, the tangent plane of trigger piece is "ten" font.
The invention has the beneficial effects that:
(1) the tabletting equipment for producing the metformin hydrochloride sustained-release tablets convenient for threshing is characterized in that the tabletting machine is connected with a stamping structure for stamping metformin hydrochloride granules into tablets, and the metformin hydrochloride granules can be rapidly stamped into the tablets through the stamping structure, namely: the metformin hydrochloride particles are poured into a tablet press, the tablet press is started, the metformin hydrochloride particles enter a cylindrical punching groove formed by a punch die and a lower punch, the punch die, the upper punch and the lower punch synchronously rotate, the upper punch moves towards the punch die, the bottom end of the lower punch enters the cylindrical punching groove formed by the punch die and the lower punch, the metformin hydrochloride particles in the punching groove are punched, the metformin hydrochloride particles are punched into tablets, the punch die, the upper punch and the lower punch continuously rotate, the upper punch is separated from the punch die, the lower punch slides towards the top end of the punch die, the tablets in the punch die are pushed out of the surface of the punch die, and the tablets are scraped by the tablet press, so that the operation of punching the metformin hydrochloride particles into the tablets is completed.
(2) The tabletting equipment for producing the metformin hydrochloride sustained release tablets convenient for threshing, disclosed by the invention, is characterized in that a stamping structure is provided with a gas compression structure for gas injection, the stamping structure is connected with a compression structure for pressurizing the gas compression structure, gas can be compressed under the matching of the gas compression structure and the compression structure, and after metformin hydrochloride particles are punched into tablets, gas injection is facilitated to accelerate separation, namely: when punching to the top of die when sliding down, the clamping ring will contradict with the bottom of die, the undershoot continues to move to the die top, thereby make the clamping ring drive depression bar along second spout and undershoot sliding fit, make the undershoot move to the clamp plate direction, thereby alright pressurize the gasbag, thereby be convenient for discharge the inside gas of gasbag, when the gasbag is compressed, because the rubber buffer is closed state, the gasbag volume will diminish, the gasbag is with gaseous input air chamber, the gasbag will move to the backup pad direction, when gasbag internal pressure continues to increase, the clamp plate will promote the gasbag and move to the backup pad direction, the backup pad will move downwards, thereby make the compression of third spring, prevent that the gasbag from damaging because of internal pressure is too big, wait to jet-blast acceleration to break away from to it behind the punching into the tablet of metformin hydrochloride granule.
(3) The tabletting equipment for producing the metformin hydrochloride sustained release tablets convenient for threshing, disclosed by the invention, has the advantages that the stamping structure is provided with the opening and closing structure for controlling the gas flow, the stamping structure is provided with the touch structure for touching the opening and closing structure to work, and under the matching of the opening and closing structure and the touch structure, when the pressed metformin hydrochloride sustained release tablets are separated, gas is sprayed to the tablets, so that the tablets can be quickly separated from the stamping structure, the damage caused by the adhesion of the tablets and the stamping structure is avoided, and the quality of the tablets is improved, namely: when the air bag is compressed, the air in the air bag enters the air chamber through the air pipe, the air in the air chamber pushes the rubber plug, the rubber plug is tightly abutted with the lower punch under the action of the second spring, so that the rubber plug cannot be opened, the air in the air chamber cannot be sprayed out from the rubber ring, when the lower punch moves to the surface of the punch die, the air bag is continuously compressed, the air pressure in the air chamber is continuously increased, the contact ring slides to one end, close to the upper punch, of the first chute, is abutted against the punch die, the lower punch continues to move, so that the contact ring pulls the contact rod to move, the contact rod pulls the contact block to move, the contact block pushes the rubber plug to move, the top end of the contact block is separated from the rubber ring, the first spring is compressed, the rubber plug moves towards the second spring, the second spring is compressed, the lower punch is separated from the rubber plug, so that the air chamber is communicated with the outside, at this moment, the lower punch moves to the surface of the punch die with the tablet, and the air pressure in the air chamber enables air to be sprayed out from the rubber ring, so that the tablet adhered to the top end of the lower punch is pushed away, thereby being convenient for quick threshing, and under the cooperation of the tablet press, the tablet is completely scraped from the punch die, so that the tablet is conveniently and quickly separated from the tablet press, the tablet is prevented from being adhered to the lower punch to cause damage, and the quality of the tablet is improved.
Drawings
The invention is further illustrated with reference to the following figures and examples.
FIG. 1 is a schematic structural diagram of the overall structure of a preferred embodiment of a tabletting device for producing a metformin hydrochloride sustained release tablet which is convenient to thresh provided by the present invention;
FIG. 2 is an enlarged view of the part A shown in FIG. 1;
FIG. 3 is a schematic view of the connection of the die and the lower punch shown in FIG. 2;
FIG. 4 is an enlarged view of the structure of the portion B shown in FIG. 3;
FIG. 5 is an enlarged view of the structure of the portion C shown in FIG. 3;
fig. 6 is a schematic view of a connection structure of the pressure ring and the undershoot shown in fig. 5.
In the figure: 1. the tablet press comprises a tablet press, 2, a stamping structure, 21, an upper punch, 22, a die, 23, a lower punch, 3, a touch structure, 31, a touch block, 32, a rubber ring, 33, a touch rod, 34, a first spring, 35, a first sliding groove, 36, a touch ring, 37, a sealing ring, 4, an opening and closing structure, 41, a second spring, 42, a rubber plug, 43, an air chamber, 44, an air pipe, 5, a gas compression structure, 51, an air bag, 52, a supporting plate, 53, a third spring, 6, a compression structure, 61, a pressing plate, 62, a pressing rod, 63, a pressing ring, 64 and a second sliding groove.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
As shown in fig. 1-6, the tabletting equipment for producing the metformin hydrochloride sustained release tablet convenient for degranulation comprises a tabletting machine 1, wherein the tabletting machine 1 is connected with a stamping structure 2 for stamping metformin hydrochloride particles into tablets, the stamping structure 2 is provided with a gas compression structure 5 for gas injection, the stamping structure 2 is connected with a compression structure 6 for pressurizing the gas compression structure 5, the stamping structure 2 is provided with an opening and closing structure 4 for controlling gas flow, and the stamping structure 2 is provided with a trigger structure 3 for triggering the opening and closing structure 4 to work.
Specifically, the stamping structure 2 comprises an upper punch 21, the tablet press 1 is rotationally connected with the upper punch 21, the tablet press 1 is rotationally connected with a punch 22, the upper punch 21 is slidably connected with the punch 22, the tablet press 1 is rotationally connected with a lower punch 23, and the punch 22 is slidably connected with the lower punch 23; the metformin hydrochloride particles are poured into the tablet press machine 1, the tablet press machine 1 is started, the metformin hydrochloride particles enter a cylindrical punching groove formed by a punch 22 and a lower punch 23, the punch 22, an upper punch 21 and the lower punch 23 rotate synchronously, the upper punch 21 moves towards the punch 22, the bottom end of the lower punch 23 enters the cylindrical punching groove formed by the punch 22 and the lower punch 23, the metformin hydrochloride particles in the punching groove are punched, the metformin hydrochloride particles are punched into tablets, the punch 22, the upper punch 21 and the lower punch 23 continue to rotate, the upper punch 21 is separated from the punch 22, the lower punch 23 slides towards the top end of the punch 22, the tablets in the punch 22 are pushed out of the surface of the punch 22, and the tablets are scraped by the tablet press machine 1, so that the metformin hydrochloride particles are punched into the tablets.
Specifically, the air compressing structure 5 comprises a third spring 53, the third spring 53 is fixedly connected inside the lower punch 23, the other end of the third spring 53 is fixedly connected with a support plate 52, the top end of the support plate 52 is fixedly connected with an air bag 51, the air bag 51 is cylindrical, and the support plate 52 is in a round cake shape; when the air bag 51 is compressed, the volume of the air bag 51 is reduced due to the closing state of the rubber stopper 42, the air bag 51 inputs air into the air chamber 43, the air bag 51 moves towards the direction of the support plate 52, when the internal pressure of the air bag 51 continues to increase, the pressure plate 61 pushes the air bag 51 to move towards the direction of the support plate 52, the support plate 52 moves downwards, so that the third spring 53 is compressed, the air bag 51 is prevented from being damaged due to the excessive internal pressure, and after the metformin hydrochloride particles are punched into tablets, the metformin hydrochloride particles can be conveniently sprayed with air to accelerate the disengagement.
Specifically, the compression structure 6 comprises a pressure plate 61, the top end of the air bag 51 is fixedly connected with the pressure plate 61, two ends of the pressure plate 61 are fixedly connected with pressure rods 62, a pair of second sliding grooves 64 are arranged on the pressure rods 62, the pressure rods 62 are slidably connected with the lower punch 23 through the second sliding grooves 64, the lower punch 23 is slidably connected with a pressure ring 63, the pair of pressure rods 62 are fixedly connected with the pressure ring 63, the pressure plate 61 is in a round cake shape, and the pressure rods 62 are in an L shape; when the lower punch 23 slides towards the top end of the die 22, the press ring 63 collides with the bottom end of the die 22, and the lower punch 23 continues to move towards the top end of the die 22, so that the press ring 63 drives the press rod 62 to slide and match with the lower punch 23 along the second slide groove 64, the lower punch 23 moves towards the press plate 61, the airbag 51 can be pressurized, and the gas in the airbag 51 can be conveniently discharged.
Specifically, the opening and closing structure 4 includes an air chamber 43, the air chamber 43 is arranged inside the lower punch 23, the air pipe 44 is fixedly connected inside the lower punch 23, one end of the air pipe 44 is communicated with the air chamber 43, the other end of the air pipe 44 penetrates through the pressure plate 61 to be communicated with the inside of the air bag 51, the second spring 41 is fixedly connected inside the lower punch 23, the rubber plug 42 is fixedly connected to the top end of the second spring 41, the top end of the rubber plug 42 is abutted against the lower punch 23, the air chamber 43 is communicated with the outside through the rubber plug 42, the air chamber 43 is cylindrical, and the air pipe 44 is spiral; when the air bag 51 is compressed, the gas in the air bag 51 enters the air chamber 43 through the air tube 44, the gas in the air chamber 43 pushes the rubber stopper 42, and the rubber stopper 42 tightly collides with the lower punch 23 under the action of the second spring 41, so that the rubber stopper 42 cannot be opened, and the gas in the air chamber 43 cannot be ejected out of the rubber ring 32.
Specifically, the trigger structure 3 comprises a trigger block 31, the interior of the lower punch 23 is slidably connected with the trigger block 31, the top end of the lower punch 23 is fixedly connected with a rubber ring 32, the top end of the touch block 31 is connected with the rubber ring 32 in a sliding way, the bottom end of the touch block 31 is abutted against the top end of the rubber plug 42, the two ends of the touch block 31 are fixedly connected with touch rods 33, the touch rod 33 is connected with the lower punch 23 in a sliding way, the touch rod 33 is sleeved with a sealing ring 37 and is connected with the sealing ring 37 in a sliding way, the sealing ring 37 is fixedly connected with the lower punch 23, the lower punch 23 is sleeved with the contact ring 36, the contact ring 36 is fixedly connected with the contact rod 33, the die 22 is provided with a first sliding chute 35, the contact ring 36 is connected with the punch die 22 in a sliding manner through a first sliding chute 35, the contact rod 33 is in an L shape, and the section of the contact block 31 is in a cross shape; when the lower punch 23 is going to move to the surface of the die 22, the air bag 51 continues to be compressed, the air pressure inside the air chamber 43 continues to increase, at this time, the contact ring 36 slides to the end of the first chute 35 close to the upper punch 21, the contact ring 36 is in contact with the die 22, the lower punch 23 continues to move, so that the contact ring 36 pulls the contact rod 33 to move, the contact rod 33 pulls the trigger block 31 to move, the trigger block 31 pushes the rubber plug 42 to move, the top end of the trigger block 31 is separated from the rubber ring 32, the first spring 34 is compressed, the rubber plug 42 moves towards the second spring 41, the second spring 41 is compressed, the rubber plug 42 is separated from the lower punch 23, so that the air chamber 43 is communicated with the outside, at this time, the lower punch 23 moves to the surface of the die 22 with tablets, the air pressure inside the air chamber 43 causes the air to be ejected from the rubber ring 32, so that the tablets adhered to the top end of the lower punch 23 are pushed away, thereby facilitating quick threshing, under the cooperation of the tablet press 1, the tablet is completely scraped from the punch die 22, so that the tablet is conveniently and quickly separated from the tablet press 1, the damage caused by the adhesion of the tablet and the adhesion of the lower punch 23 is avoided, and the quality of the tablet is improved.
When the invention is used, firstly, the metformin hydrochloride granules are poured into the tablet press machine 1, the tablet press machine 1 is started, the metformin hydrochloride granules enter a cylindrical punching groove formed by a punch 22 and a lower punch 23, the punch 22, the upper punch 21 and the lower punch 23 synchronously rotate, the upper punch 21 moves towards the punch 22, the bottom end of the lower punch 23 enters the cylindrical punching groove formed by the punch 22 and the lower punch 23, the metformin hydrochloride granules in the punching groove are punched, the metformin hydrochloride granules are punched into tablets, the punch 22, the upper punch 21 and the lower punch 23 continuously rotate, the upper punch 21 is separated from the punch 22, the lower punch 23 slides towards the top end of the punch 22, the tablets in the punch 22 are pushed out of the surface of the punch 22, the tablets are scraped by the tablet press machine 1, so that the operation of punching the metformin hydrochloride granules into the tablets is completed, when the lower punch 23 slides towards the top end of the punch 22, the press ring 63 will collide with the bottom end of the die 22, the lower punch 23 will move towards the top end of the die 22, so that the press ring 63 drives the press rod 62 to slide-fit with the lower punch 23 along the second slide groove 64, the lower punch 23 will move towards the press plate 61, so as to pressurize the air bag 51, thereby facilitating the discharge of the gas inside the air bag 51, when the air bag 51 is compressed, because the rubber plug 42 is in a closed state, the volume of the air bag 51 will become small, the air bag 51 will input the gas into the air chamber 43, the air bag 51 will move towards the support plate 52, when the internal pressure of the air bag 51 continues to increase, the press plate 61 will push the air bag 51 to move towards the support plate 52, the support plate 52 will move downwards, thereby compressing the third spring 53, preventing the air bag 51 from being damaged due to the excessive internal pressure, after the metformin hydrochloride particles are punched into tablets, the air injection acceleration separation can be performed, when the air bag 51 is compressed, the gas in the air bag 51 enters the air chamber 43 through the gas pipe 44, the gas in the air chamber 43 pushes the rubber plug 42, the rubber plug 42 tightly collides with the lower punch 23 under the action of the second spring 41, so that the rubber plug 42 cannot be opened, the gas in the air chamber 43 cannot be ejected from the rubber ring 32, when the lower punch 23 is about to move to the surface of the die 22, the air bag 51 continues to compress, the gas pressure in the air chamber 43 continues to increase, at this time, the abutting ring 36 slides to the end of the first chute 35 close to the upper punch 21, the abutting ring 36 collides with the die 22, the lower punch 23 continues to move, so that the abutting ring 36 pulls the abutting rod 33 to move, the abutting rod 33 pulls the trigger block 31 to move, the trigger block 31 pushes the rubber plug 42 to move, the top end of the trigger block 31 is separated from the rubber ring 32, the first spring 34 compresses, the rubber plug 42 moves towards the second spring 41, the second spring 41 compresses, the rubber plug 42 is separated from the lower punch 23, so that the air chamber 43 is communicated with the outside, at this time, the lower punch 23 moves to the surface of the punch die 22 together with the tablets, the air pressure in the air chamber 43 will make the air jet out of the rubber ring 32, so that the tablets adhered to the top end of the lower punch 23 are pushed away, thereby facilitating quick threshing, under the cooperation of the tablet press 1, the tablets are completely scraped from the punch die 22, thereby facilitating the quick separation of the tablets from the tablet press 1, avoiding the adhesion of the tablets and the lower punch 23 to cause damage, improving the quality of the tablets, when the tablets are separated, the lower punch 23 will move to the bottom end of the punch die 22, the contact ring 36 will move to the bottom end of the first chute 35, under the action of the first spring 34, the top end of the contact block 31 will reset to the rubber ring 32, the bottom end of the contact block 31 will separate from the rubber plug 42, under the action of the second spring 41, the rubber plug 42 will again contact with the lower punch 23, therefore, the air chamber 43 is blocked from communicating with the outside, the next work is carried out, when the lower punch 23 moves to the bottom end of the die 22, the third spring 53 pushes the supporting plate 52 to reset, the air bag 51 sucks air to expand, and the pressing rod 62 drives the pressing ring 63 to reset, so that the next work is facilitated.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (10)

1. The utility model provides a tabletting equipment is used in production of metformin hydrochloride sustained release tablet convenient to thresh, a serial communication port, including tablet press (1), tablet press (1) is connected with stamping structure (2) that are used for punching into the tablet with the metformin hydrochloride granule, stamping structure (2) are installed and are used for jet-propelled compressed air structure (5), stamping structure (2) are connected with and are used for carrying out pressor compression structure (6) to compressed air structure (5), open and close structure (4) that are used for controlling the gas flow are installed in stamping structure (2), stamping structure (2) are installed and are used for touching open and close structure (4) and carry out touching structure (3) of work.
2. The tabletting equipment for producing metformin hydrochloride sustained release tablets facilitating degranulation according to claim 1, wherein: stamping structure (2) are including going up punch (21), tablet press (1) rotate to be connected with goes up punch (21), tablet press (1) rotate to be connected with die (22), go up punch (21) and die (22) sliding connection, tablet press (1) rotate to be connected with down punch (23), die (22) and down punch (23) sliding connection.
3. The tabletting equipment for producing metformin hydrochloride sustained release tablets facilitating degranulation according to claim 2, wherein: the air compression structure (5) comprises a third spring (53), the third spring (53) is fixedly connected to the inner portion of the lower punch (23), a supporting plate (52) is fixedly connected to the other end of the third spring (53), and an air bag (51) is fixedly connected to the top end of the supporting plate (52).
4. The tabletting equipment for producing metformin hydrochloride sustained release tablets facilitating degranulation according to claim 3, wherein: the air bag (51) is cylindrical, and the supporting plate (52) is in a round cake shape.
5. The tabletting equipment for producing metformin hydrochloride sustained release tablets facilitating degranulation according to claim 4, wherein: compression structure (6) are including clamp plate (61), the top fixedly connected with clamp plate (61) of gasbag (51), both ends fixedly connected with depression bar (62) of clamp plate (61), be equipped with a pair of second spout (64) on depression bar (62), depression bar (62) are through second spout (64) and down punch (23) sliding connection, down punch (23) sliding connection has clamping ring (63), and is a pair of depression bar (62) and clamping ring (63) fixed connection.
6. The tabletting equipment for producing metformin hydrochloride sustained release tablets facilitating degranulation according to claim 5, wherein: the pressing plate (61) is in a round cake shape, and the pressing rod (62) is in an L shape.
7. The tabletting equipment for producing metformin hydrochloride sustained release tablets facilitating degranulation according to claim 6, wherein: opening and closing structure (4) include air chamber (43), down punch (23) inside is equipped with air chamber (43), down punch (23) inside fixedly connected with trachea (44), the one end and air chamber (43) intercommunication of trachea (44), trachea (44) other end runs through in the inside intercommunication of clamp plate (61) and gasbag (51), down punch (23) inside fixedly connected with second spring (41), the top fixedly connected with rubber buffer (42) of second spring (41), the top of rubber buffer (42) and down punch (23) conflict, air chamber (43) are through rubber buffer (42) and outside intercommunication.
8. The tabletting equipment for producing metformin hydrochloride sustained release tablets facilitating degranulation according to claim 7, wherein: the air chamber (43) is cylindrical, and the air pipe (44) is spiral.
9. The tabletting equipment for producing metformin hydrochloride sustained release tablets facilitating degranulation according to claim 8, wherein: the touch structure (3) comprises a touch block (31), the lower punch (23) is connected with the touch block (31) in a sliding way, the top end of the lower punch (23) is fixedly connected with a rubber ring (32), the top end of the touch block (31) is connected with the rubber ring (32) in a sliding way, the bottom end of the touch block (31) is abutted against the top end of the rubber plug (42), both ends of the touch block (31) are fixedly connected with touch rods (33), the touch rod (33) is connected with the lower punch (23) in a sliding way, the touch rod (33) is sleeved with a sealing ring (37) and is connected with the sealing ring (37) in a sliding way, the sealing ring (37) is fixedly connected with the lower punch (23), the lower punch (23) is sleeved with a contact ring (36), the contact ring (36) is fixedly connected with the contact rod (33), the punch die (22) is provided with a first sliding chute (35), the contact ring (36) is connected with the punch die (22) in a sliding mode through a first sliding groove (35).
10. The tabletting equipment for producing metformin hydrochloride sustained release tablets facilitating degranulation according to claim 9, wherein: the touch rod (33) is L-shaped, and the cross section of the touch block (31) is cross-shaped.
CN202110818721.3A 2021-07-20 2021-07-20 Tabletting equipment is used in production of metformin hydrochloride sustained-release tablet convenient to thresh Pending CN113580649A (en)

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US6964779B1 (en) * 1998-04-08 2005-11-15 Kyowa Hakko Kogyo Co., Ltd. Tablet manufacturing method and tablet
CN204936270U (en) * 2015-09-28 2016-01-06 平湖市海特合金有限公司 With the powder compaction press of blowing device
CN106217932A (en) * 2016-08-30 2016-12-14 重庆市扬昇药业有限公司 The tablet machine of pneumatic flushing unloading piece
CN206968043U (en) * 2017-06-29 2018-02-06 北京费森尤斯卡比医药有限公司 A kind of tablet press machine blown with discharging opening baffle plate buffering
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CN213198931U (en) * 2020-09-10 2021-05-14 吉林省中晟制药有限公司 Stamping structure of high-speed tablet press

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