CN113576416A - Method and device for improving hand tremor - Google Patents
Method and device for improving hand tremor Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
- A61B5/0022—Monitoring a patient using a global network, e.g. telephone networks, internet
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1101—Detecting tremor
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- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36031—Control systems using physiological parameters for adjustment
Abstract
A method and device for improving hand tremor, the method comprising: acquiring three-dimensional acceleration data and myoelectric data, determining a prescription based on the three-dimensional acceleration data and the myoelectric data, selecting an electrical stimulation waveform according to the determined prescription, and stimulating the wrist radial nerve by using the selected electrical stimulation waveform. The scheme of determining the prescription based on tremor detection can adopt a targeted electrical stimulation prescription according to different tremor conditions, is suitable for treatment of different illness states and different patients, and meanwhile improves the flexibility of an electrical stimulation treatment scheme through a timely and effective treatment feedback channel.
Description
Technical Field
The invention belongs to the field of medical detection, and particularly relates to a method and a device for improving hand tremor.
Background
Usually, an unintended tremor occurs in a part of the human body, which is medically known as "tremor". Tremor is commonly found in the limbs and head of the human body and is one of the most common neurological diseases, such as Essential Tremor (ET), Parkinson's Disease (PD), etc. The pathological tremor is tremor caused by pathological changes of human bodies and can move along with the movement of the human bodies all the time, and the pathological tremor has the characteristics of large amplitude and low frequency. Although tremor does not directly harm life, it brings inconvenience to life for many patients and reduces the quality of life of the patients.
The assessment of the symptom of the motor dysfunction of the tremor patients in early clinical practice mainly depends on a scoring scale, but the scoring method is influenced by the operation experience and subjectivity of scoring doctors, and the assessment of the motor function of the tremor patients by the scoring scale is not objective and accurate enough, so that the early diagnosis and the stage of the tremor patients are influenced; in recent years, a patient is provided with wearable equipment to measure hand movements by utilizing an accelerometer, and then tremor is identified, however, the identification precision of the method is limited, the algorithm is usually very crude, physiological tremor or pathological tremor cannot be accurately and truly distinguished, and the measurement is easily affected by personal physiological characteristics, equipment and other noises, so that the measurement result is inaccurate, and even the situation of repeated measurement occurs.
The traditional tremor treatment scheme mainly takes medicines as main medicines to inhibit specific nerve conduction and neuron activity, but the effect is not ideal and the medicine property is easy to generate. The treatment period of the electrical stimulation method is long, and the method is difficult to apply to clinic. With the iterative upgrade of wearable equipment, the wearable equipment represented by Cala Trio can measure specific tremor and send mild stimulation to the nervous system of a human body, and the tremor of a part of thalamus ventral medial nucleus is interrupted, so that the hand tremor condition of a patient can be relieved.
While Trio combines modern medical technology with advanced equipment technology, it is clearly only an initial product. The Trio has a single electrical stimulation mode, so that the Trio cannot be effectively applied to different diseases and different patients; the treatment effect of the Trio on the patient cannot be monitored and fed back in time, the treatment scheme cannot be adjusted adaptively, and the patient may need to frequently go to a hospital to detect and modify the treatment scheme.
Disclosure of Invention
To solve at least one of the above problems, the present invention aims to provide a flexible and effective method and device for improving hand tremor.
In a first aspect, there is provided a method of improving hand tremor, comprising: step 1, collecting three-dimensional acceleration data and myoelectric data; step 2, determining a prescription based on the three-dimensional acceleration data and the myoelectric data; step 3, selecting an electrical stimulation waveform according to the determined prescription; and 4, stimulating the radial nerve of the wrist by using the selected electrical stimulation waveform. Based on the acquired three-dimensional acceleration and myoelectric data, the tremor condition of the patient can be accurately fed back and recognized, different electrical stimulation prescriptions are determined according to different tremor conditions, and the method can be effectively suitable for treatment of different conditions and different patients.
Optionally, a corresponding relationship between the specific prescription and the three-dimensional acceleration data and the electromyographic data is pre-stored, and in step 2, the prescription is determined by using the pre-stored corresponding relationship. Therefore, the most suitable prescription can be determined for the patient at any time and any place, and the patient can adapt to different disease conditions. Preferably, in step 2, the three-dimensional acceleration data and the electromyographic data are sent to a remote monitoring terminal, and a prescription is determined through the remote monitoring terminal. Generally, the medical staff at the monitoring side has more professional and comprehensive medical knowledge, and can determine the prescription with the best treatment effect for the patient.
Further, each prescription corresponds to at least two electrical stimulation waveforms for selection; different electrical stimulation waveforms have different amplitudes and/or frequencies. The patient can select the electrostimulation waveform meeting the self requirement according to different situation requirements and different real-time requirements, so that the flexibility of the electrostimulation treatment scheme is further improved.
In a second aspect, there is provided a device for improving hand tremor, comprising: the device comprises a first electrode plate group, a second electrode plate group, a myoelectric data acquisition circuit, an acceleration detection circuit, a main control chip, an electrical stimulation waveform control circuit and a key; the myoelectric data acquisition circuit is electrically connected with the second electrode plate group and used for acquiring myoelectric data, the acceleration detection circuit is used for acquiring three-dimensional acceleration data, and the myoelectric data acquisition circuit and the acceleration detection circuit respectively send the acquired myoelectric data and the three-dimensional acceleration data to the main control chip; the main control chip determines a prescription based on the three-dimensional acceleration data and the myoelectric data, an electrical stimulation waveform corresponding to the prescription is selected through a key, the main control chip sends the selected electrical stimulation waveform to the electrical stimulation waveform control circuit, and the electrical stimulation waveform control circuit generates the corresponding electrical stimulation waveform and transmits the electrical stimulation waveform to the first electrode plate group.
Optionally, the device further comprises a storage circuit for pre-storing a corresponding relation between a specific prescription and the three-dimensional acceleration data and the electromyographic data, and the main control chip determines the prescription by using the pre-stored corresponding relation, the three-dimensional acceleration data and the electromyographic data. Each prescription corresponds to at least two electrical stimulation waveforms for selection; the different electrical stimulation waveforms have different amplitudes and/or frequencies, and information of each prescription and all corresponding electrical stimulation waveforms is stored in the storage circuit.
Optionally, the device further includes a communication component, and the main control chip sends the three-dimensional acceleration data and the myoelectric data to a remote monitoring terminal through the communication component, and the remote monitoring terminal determines the prescription and transmits the prescription back to the main control chip through the communication component. Preferably, the communication component is a short-range communication component, and the device is connected with the intelligent terminal or the gateway in a pairing mode through the short-range communication component.
Further, the device further comprises a display component, and the display component is used for displaying the information of the prescription and/or the information of the electric stimulation waveform.
Furthermore, the device is wearable equipment, and the first electrode plate group is located the wrist radial nerve after wearing.
In a third aspect, there is provided a computer-readable storage medium having stored thereon computer-executable instructions which, when executed by a processor, implement the method of the first aspect of the invention. There is also provided a computer apparatus comprising storage means and processing means, the storage means storing a computer program which, when executed by the processing means, causes the computer apparatus to carry out the method of the first aspect of the invention.
According to the first to third aspects of the present invention, the following advantageous effects can be achieved: 1. hand tremor detection and treatment are integrated, the treatment mode is flexibly determined according to the actual condition, and the treatment effect is improved; 2. the treatment state is monitored and fed back in real time, specific nerves are stimulated accurately, so that doctors and patients can master treatment progress in time, and a treatment scheme can be adjusted at any time to ensure the optimal treatment effect; 3. in the daily treatment process of a patient, the frequency and the amplitude of an electrical stimulation waveform can be properly adjusted according to different requirements of different scenes, and the use experience is considered on the basis of ensuring the treatment effect.
Additional features and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention.
Drawings
FIG. 1 shows a schematic view of a method of improving hand tremor according to a first embodiment of the invention;
fig. 2 is a schematic structural diagram of a device for improving hand tremor according to a second embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without inventive effort based on the embodiments of the present invention, are within the scope of the present invention.
According to a first embodiment of the present invention, as shown in fig. 1, there is provided a method of improving hand tremor, comprising:
step 1, collecting three-dimensional acceleration data and myoelectric data.
Tremor is a repetitive, graduated motion with some regularity in both frequency and amplitude. The types of tremor are many and easy to confuse, Parkinson's tremor and essential tremor are two diseases which are most easily confused and misdiagnosed, sometimes other types of tremor or various dyskinesias are difficult to distinguish only through clinical manifestations, but diagnosis can be assisted through electrophysiological detection, and compared with simple clinical assessment or acceleration assessment, analysis of tremor through electrophysiological examination can more reliably determine the regularity of tremor, and can be used for distinguishing typical tremor syndromes (which are generally regular) from myoclonus syndromes or psychogenic syndromes (which are generally irregular).
The three-dimensional acceleration data and the myoelectric data are collected to diagnose the tremor state of an illness and determine the actual tremor characteristics of different patients so as to provide a prescription with the best treatment effect in the follow-up process, thereby effectively improving the tremor state of an illness.
And 2, determining a prescription based on the three-dimensional acceleration data and the myoelectric data. Specifically, the correspondence relationship between each prescription and the three-dimensional acceleration data and the myoelectric data may be stored in advance, for example, a certain three-dimensional acceleration data has the feature Ca1A certain electromyographic data has a characteristic Ce1Then, it corresponds to the first prescription R1(ii) a The other three-dimensional acceleration data having a characteristic Ca2The other electromyographic data has a characteristic Ce2Then, it corresponds to the second prescription R2(ii) a … …, and so on, these correspondences are usually set according to a large number of clinical practice experiences. Acceleration data can assist us in understanding the frequency, amplitude and rhythmicity of tremor, and electromyography can be used to assess the regularity, burst pattern and duration of tremors. The tremor situation is detected comprehensively by recording one or more pairs of electromyographic signals of muscles which move synchronously. Different characteristics actually reflect different illness states of the patient, corresponding prescriptions are designed and stored in advance according to different illness states, and the prescriptions are determined by utilizing the preset corresponding relation, so that the most appropriate prescription can be determined for the patient at any time and any place, and the patient can adapt to different illness states.
Optionally, in step 2, the three-dimensional acceleration data and the electromyographic data may also be sent to a remote monitoring terminal by using a remote communication technology, so as to determine the prescription through the remote monitoring terminal. Generally, a remote monitoring terminal is arranged in a hospital or a rehabilitation center and is monitored by medical staff with professional medical knowledge, so that a prescription with the best treatment effect can be determined for a patient, and on one hand, the loophole that the pre-stored preset relationship cannot be covered comprehensively is made up; on the other hand, medical staff can monitor the treatment effect in real time, and can adjust the prescription manually and remotely guide the treatment in manual and automatic ways if the improvement effect is not good enough or the treatment effect is not in compliance with the medical advice.
And 3, selecting an electrical stimulation waveform according to the determined prescription.
Each prescription corresponds to at least two electrical stimulation waveforms for selection by the patient, with different electrical stimulation waveforms having different amplitudes and/or frequencies. The patient can select the electrostimulation waveform meeting the self-demand in the prescription according to different situation demands and different real-time demands, for example, the amplitude of the electrostimulation waveform can be properly weakened when the patient needs to concentrate on work at a desk, the lower-frequency electrostimulation waveform can be selected when the patient has a rest in the noon, and the default or higher-amplitude electrostimulation waveform can be selected when the patient moves daily, so that the flexibility of the electrostimulation treatment scheme can be further improved according to the actual scene and the actual demands of the patient.
And 4, stimulating the radial nerve of the wrist by using the selected electrical stimulation waveform. Based on the acquired three-dimensional acceleration and myoelectric data, the tremor condition of the patient can be accurately fed back and recognized, different electrical stimulation prescriptions are determined according to different tremor conditions, and the method can be effectively suitable for treatment of different conditions and different patients.
According to a second embodiment of the present invention, as shown in fig. 2, there is provided a device for improving hand tremor, comprising: the device comprises a first electrode plate group, a second electrode plate group, a myoelectric data acquisition circuit, an acceleration detection circuit, a main control chip, an electrical stimulation waveform control circuit and a key. The device for improving hand tremor of this embodiment is preferably wearable equipment, for example intelligent bracelet, intelligent watchband, intelligent wrist-watch etc. and the patient can reach the purpose of long-term electrostimulation treatment through daily wearing.
In order to track the treatment effect and adjust the treatment scheme according to the state of illness in due time, the device for improving hand tremor in the embodiment is provided with a component for detecting tremor: the myoelectric data acquisition circuit is electrically connected with the second electrode plate group and used for acquiring myoelectric data, and the acceleration detection circuit is used for acquiring three-dimensional acceleration data. Acceleration data can assist us in understanding the frequency, amplitude and rhythmicity of tremor, and electromyography can be used to assess the regularity, burst pattern and duration of tremors. The actual tremor condition of the patient can be comprehensively obtained by recording one or more pairs of electromyographic signals of muscles which move synchronously. In this embodiment, the electromyographic data of the specific muscle of the wrist, such as the extensor carpi radialis, flexor carpi radialis, extensor carpi ulnaris, flexor carpi ulnaris, etc., of the wrist, is acquired through the second electrode plate group by using the paired muscle electrical signal differential sensors.
After acquiring and acquiring the tremor signal, the electromyographic data acquisition circuit and the acceleration detection circuit respectively send the acquired electromyographic data and the three-dimensional acceleration data to the main control chip. The main control chip is a core component with a data processing function in the device for improving hand tremor in the embodiment, and is connected with most functional components in the device, namely, the main control chip receives the acquired data of the tremor detection component, is connected with the communication component to realize external interaction, is connected with components such as local keys and display to realize local functions, and is connected with the electrical stimulation waveform control circuit to realize treatment control. Meanwhile, the main control chip has certain signal processing capacity, and the main control chip can determine a prescription based on the three-dimensional acceleration data and the myoelectric data sent by the acceleration detection circuit and the myoelectric data acquisition circuit. Specifically, the corresponding relation between the specific prescription and the three-dimensional acceleration data and the myoelectric data is pre-stored through the storage circuit, the pre-stored corresponding relation can be called by the main control chip, and then the optimal prescription is determined through the three-dimensional acceleration data and the myoelectric data. The correspondence between the prescription, the three-dimensional acceleration data and the electromyographic data is the same as that in the first embodiment of the present invention, and is obtained according to sufficient clinical practice experience. The storage circuit is also stored with information of each prescription and corresponding electrical stimulation waveforms, each prescription corresponds to at least two electrical stimulation waveforms for selection, and different electrical stimulation waveforms have different amplitudes and/or frequencies. The patient can select the electrical stimulation waveform corresponding to the prescription through keys, and can also view information of the prescription and/or information of the electrical stimulation waveform selected by the patient through the display component.
The main control chip receives the key selection information and sends the selected electrical stimulation waveform to the electrical stimulation waveform control circuit so as to generate a corresponding electrical stimulation waveform and transmit the corresponding electrical stimulation waveform to the first electrode plate group. Preferably, after wearing the device for improving hand tremor of this embodiment, the first electrode plate set is located at the radial nerve of the wrist, and the second electrode plate set is located at the radial and ulnar wrist, extensor carpi and flexor carpi muscles. In case of improper position, the adjustment can be performed by the strap adjusting device. For certain waveforms, it may be desirable to utilize a boost circuit to allow the resulting electrical stimulation waveform to meet the waveform requirements selected by the patient.
Optionally, the main control chip may further send the acquired three-dimensional acceleration data and the acquired electromyographic data to a remote monitoring terminal through a communication component, and the remote monitoring terminal determines the prescription and receives the prescription returned by the remote monitoring terminal. Generally, a remote monitoring terminal is arranged in a hospital or a rehabilitation center and is monitored by medical staff with professional medical knowledge, so that a prescription with the best treatment effect can be determined for a patient, and on one hand, the loophole that the pre-stored preset relationship cannot be covered comprehensively is made up; on the other hand, medical staff can monitor the treatment effect in real time, and can adjust the prescription manually and remotely guide the treatment in manual and automatic ways if the improvement effect is not good enough or the treatment effect is not in compliance with the medical advice. The communication component is preferably a short-distance communication component, such as a wireless fidelity (WiFi), a BLUETOOTH (BLUETOOTH), a wireless carrier ultra-wideband (UWB), and the like, and the device for improving hand tremor of the embodiment can be connected with an intelligent terminal (and a client) or a gateway in a pairing manner, so that information interaction is realized through a wide area network, a server and a remote monitoring terminal located in a hospital or a rehabilitation center.
According to a third embodiment of the invention, there is provided a computer-readable storage medium having stored thereon computer-executable instructions which, when executed by a processor, implement the method in the first embodiment of the invention. There is also provided a computer apparatus comprising storage means and processing means, the storage means storing a computer program which, when executed by the processing means, causes the computer apparatus to carry out the method of the first embodiment of the invention.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that various changes in the embodiments and/or modifications of the invention can be made, and equivalents and modifications of some features of the invention can be made without departing from the spirit and scope of the invention.
Claims (14)
1. A method of improving hand tremor, comprising:
step 1, collecting three-dimensional acceleration data and myoelectric data;
step 2, determining a prescription based on the three-dimensional acceleration data and the myoelectric data;
step 3, selecting an electrical stimulation waveform according to the determined prescription;
and 4, stimulating the radial nerve of the wrist by using the selected electrical stimulation waveform.
2. A method of improving hand tremor according to claim 1, wherein the correspondence between a specific prescription and three-dimensional acceleration and electromyography data is pre-stored; in step 2, the prescription is determined by using the pre-stored correspondence.
3. A method of improving hand tremor according to claim 1, wherein step 2 specifically comprises:
and sending the three-dimensional acceleration data and the myoelectric data to a remote monitoring terminal, and determining a prescription through the remote monitoring terminal.
4. A method of improving hand tremor according to any of claims 1-3, wherein at least two electrical stimulation waveforms are selected for each prescription.
5. A method of improving hand tremor according to claim 4, wherein each of the differently prescribed electrical stimulation waveforms has a different amplitude and/or frequency.
6. A device for improving hand tremor, comprising: the device comprises a first electrode plate group, a second electrode plate group, a myoelectric data acquisition circuit, an acceleration detection circuit, a main control chip, an electrical stimulation waveform control circuit and a key; wherein the content of the first and second substances,
the myoelectric data acquisition circuit is electrically connected with the second electrode plate group and is used for acquiring myoelectric data;
the acceleration detection circuit is used for acquiring three-dimensional acceleration data;
the electromyographic data acquisition circuit and the acceleration detection circuit respectively send the acquired electromyographic data and the three-dimensional acceleration data to the main control chip;
the main control chip determines a prescription based on the three-dimensional acceleration data and the myoelectric data, selects an electrical stimulation waveform corresponding to the prescription through a key, and sends the selected electrical stimulation waveform to the electrical stimulation waveform control circuit;
the electric stimulation waveform control circuit generates corresponding electric stimulation waveforms and transmits the electric stimulation waveforms to the first electrode plate group.
7. A device for improving hand tremor according to claim 6, further comprising a memory circuit for pre-storing the correspondence between a specific prescription and the three-dimensional acceleration and electromyographic data;
and the main control chip determines a prescription by utilizing the pre-stored corresponding relation, the three-dimensional acceleration data and the myoelectric data.
8. The device for improving hand tremor of claim 7, wherein each prescription corresponds to at least two electrical stimulation waveforms for selection; the storage circuit also stores information of each prescription and all corresponding electric stimulation waveforms.
9. The device for improving hand tremor of claim 6, further comprising a communication component, wherein the main control chip sends the three-dimensional acceleration data and myoelectric data to a remote monitoring terminal through the communication component, the remote monitoring terminal determines the prescription, and transmits the prescription back to the main control chip through the communication component.
10. The device for improving hand tremor of claim 9, wherein said communication element is a short-range communication element, and said device is paired with a smart terminal or gateway through said short-range communication element.
11. A device for improving hand tremor according to any of claims 6-10, further comprising a display assembly for displaying information of the prescription and/or information of the electrical stimulation waveform.
12. The apparatus for improving hand tremor of any of claims 6-10, wherein said apparatus is a wearable device, and said first electrode pad set is located on the radial nerve of the wrist after wearing.
13. A computer-readable storage medium having stored thereon computer-executable instructions, which when executed by a processor, implement the method of any one of claims 1-5.
14. A computer device comprising storage means and processing means, characterized in that the storage means store a computer program which, when executed by the processing means, causes the computer device to carry out the method according to any one of claims 1-5.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN117085244A (en) * | 2023-08-18 | 2023-11-21 | 天津大学 | Parkinson's stationary tremor suppression system based on neuromuscular electrical stimulation |
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| US20030149457A1 (en) * | 2002-02-05 | 2003-08-07 | Neuropace, Inc. | Responsive electrical stimulation for movement disorders |
| US20140336722A1 (en) * | 2013-05-08 | 2014-11-13 | Consejo Superior De Investigaciones Cientificas (Csic) | Method and neuroprosthetic device for monitoring and suppression of pathological tremors through neurostimulation of the afferent pathways |
| CN106170244A (en) * | 2014-02-04 | 2016-11-30 | 蒂姆土库尔斯有限公司 | Wearable device |
| CN106413805A (en) * | 2014-06-02 | 2017-02-15 | 卡拉健康公司 | Systems and methods for peripheral nerve stimulation to treat tremor |
| US20170274208A1 (en) * | 2016-03-25 | 2017-09-28 | Universidad Adolfo Ibañez | Methods and Systems for Tremor Reduction |
| KR20200144901A (en) * | 2019-06-19 | 2020-12-30 | 주식회사 옴니버스 | Wearable system for tremor reduction and method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117085244A (en) * | 2023-08-18 | 2023-11-21 | 天津大学 | Parkinson's stationary tremor suppression system based on neuromuscular electrical stimulation |
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