CN113521528A - Peristaltic pump special for treating heart failure and in-vitro left heart auxiliary device system thereof - Google Patents

Peristaltic pump special for treating heart failure and in-vitro left heart auxiliary device system thereof Download PDF

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Publication number
CN113521528A
CN113521528A CN202110808997.3A CN202110808997A CN113521528A CN 113521528 A CN113521528 A CN 113521528A CN 202110808997 A CN202110808997 A CN 202110808997A CN 113521528 A CN113521528 A CN 113521528A
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CN
China
Prior art keywords
peristaltic pump
roller
rotating base
support frame
output
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN202110808997.3A
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Chinese (zh)
Inventor
陈红武
崔畅
张峰
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Nanjing Beili Medical Technology Co ltd
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Nanjing Beili Medical Technology Co ltd
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Priority to CN202110808997.3A priority Critical patent/CN113521528A/en
Publication of CN113521528A publication Critical patent/CN113521528A/en
Priority to CN202210393049.2A priority patent/CN114668966A/en
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/104—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
    • A61M60/117—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body for assisting the heart, e.g. transcutaneous or external ventricular assist devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/247—Positive displacement blood pumps
    • A61M60/253—Positive displacement blood pumps including a displacement member directly acting on the blood
    • A61M60/268—Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders
    • A61M60/279—Peristaltic pumps, e.g. roller pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/50—Details relating to control
    • A61M60/508—Electronic control means, e.g. for feedback regulation
    • A61M60/538—Regulation using real-time blood pump operational parameter data, e.g. motor current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/835—Constructional details other than related to driving of positive displacement blood pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3327—Measuring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow

Abstract

The invention relates to a peristaltic pump special for treating heart failure and an in-vitro left heart auxiliary device system thereof. The peristaltic pump comprises a shell, wherein the shell is provided with a groove, a pipeline inlet and a pipeline outlet, the pipeline inlet and the pipeline outlet are respectively communicated with the groove, and a pump rotor is arranged in the groove; the pump rotor comprises a motor, a rotating base, a supporting frame and a roller; the motor is arranged in the shell, the rotating base is in transmission connection with the motor, one end of the support frame is hinged with the rotating base, the other end of the support frame is in rotating connection with the roller, and a gap for the guide pipe to pass through is reserved between the roller and the side wall of the groove; an elastic buffer part is arranged between the rotating base and the supporting frame. The external left heart auxiliary device system takes the peristaltic pump as a power source. The output pulse pressure range of the peristaltic pump is suitable for the acceptable degree of a human body, and the requirement of serving as a power source of a left heart auxiliary device can be met; the left heart auxiliary device system can effectively realize the left heart auxiliary function, the incidence rate of long-term complications is low, and the treatment cost is greatly reduced compared with the existing treatment scheme.

Description

Peristaltic pump special for treating heart failure and in-vitro left heart auxiliary device system thereof
Technical Field
The invention relates to a peristaltic pump special for treating heart failure and an in-vitro left heart auxiliary device system comprising the peristaltic pump, and belongs to the technical field of medical instruments.
Background
At present, at least 1000 ten thousand patients with heart failure in China exist, wherein about 5 percent of patients with heart failure progress to end-stage heart failure every year, and the 1-year survival rate of the patients with end-stage heart failure is only 11 to 25 percent. For these patients with advanced heart failure, Left Ventricular Assist Devices (LVADs) have become an alternative treatment option outside of cardiac transplantation. LVAD generally involves introducing left ventricular blood flow into an auxiliary pump body, which pumps the blood flow into the aorta, thereby completely replacing left ventricular pump function.
However, traditional LVAD treatment regimens require expensive instrumentation and present a higher risk of complications such as embolism, bleeding, infection, machine malfunction, and the like. The important factor is that the pump body adopted in the treatment scheme is often a magnetic suspension axial-flow pump which needs to be in direct contact with blood, and because the pump body has a complex structure that a stator and a rotor rotate in a matched manner, the pump body can easily cause the above complication risk after being in direct contact with the blood; moreover, because the pump body directly contacts with blood, the pump body itself becomes disposable consumptive material, can't used repeatedly to improve treatment cost greatly. In addition, for the magnetic suspension pump adopting the electromagnetic driving force, the risk that the pump body operates abnormally due to external electromagnetic interference exists.
If the pump body does not need to be in direct contact with blood and a magnetic suspension structure is not adopted, the problems can be avoided. In existing medical pump bodies, peristaltic pumps can meet the above conditions. However, the existing medical peristaltic pump is mainly represented by a peristaltic pump for dialysis, and the peristaltic pump is difficult to be directly applied to the left heart auxiliary device for the following reasons: (1) the diameter of an input/output flow-switching conduit used by the left heart auxiliary device is obviously larger than that of a conduit for dialysis, and the existing medical peristaltic pump can not be directly matched and used; (2) the blood pumping amount required by the left heart auxiliary device is obviously larger than that of the conventional medical peristaltic pump, so that the left heart auxiliary device cannot meet the requirement; (3) more importantly, when the left heart auxiliary device directly pumps blood into the aorta, the output pressure of the left heart auxiliary device is kept stable, however, the output pressure of the peristaltic pump is changed in a pulse fluctuation mode, and the existing medical peristaltic pump has the problem that the pulse pressure is changed too much and easily exceeds the acceptable degree of a human body, so that the left heart auxiliary device cannot be directly used.
It was found that the invention patent No. cn201180009824.x, issued publication No. CN102762863B, discloses a peristaltic roller pump, preferably for dialysis apparatuses, comprising a rotor mounting and a rotor connectable to the rotor mounting. The rotor preferably has a plurality of marking devices, by the type and/or arrangement of which at least one property of the rotor is coded. The peristaltic roller pump further comprises a safety device having at least one detection device by means of which at least one characteristic of the rotor coded by the marking device can be checked and which can be activated as a function of at least one of these characteristics of the rotor. In this document, it is mentioned that the pressure is exerted on the pressure rollers by springs and that the mounting avoids a risk of the hose being damaged by a rapid increase in the pressure of the hose, and that in this case the maximum blocking pressure is determined by the spring constant and thus the delivery pressure of the peristaltic roller pump is limited. On one hand, the peristaltic roller pump is preferably suitable for a dialysis device, and the technical problem solved by the peristaltic roller pump is independent of the tube diameter and the pump flow rate, so the peristaltic roller pump still has the problems of the prior medical peristaltic pump in the aspects of the tube diameter and the pump flow rate; on the other hand, the peristaltic roller pump applies pressure to the squeezing roller by a spring, and the purpose is mainly to avoid that the hose is easy to damage, so that the purpose can be achieved by simply selecting a spring with a proper elastic coefficient and simply installing the spring, and the situation of the left heart auxiliary device is more complicated, and the simple structure cannot be directly applied to the left heart auxiliary device.
Disclosure of Invention
The main purposes of the invention are: the peristaltic pump overcomes the problems in the prior art, the range of the output pulse pressure is suitable for the acceptable degree of a human body, and the requirement of serving as a power source of a left heart auxiliary device can be met. And simultaneously provides a corresponding matched external left heart auxiliary device system.
The technical scheme for solving the technical problems of the invention is as follows:
a peristaltic pump special for treating heart failure comprises a shell, wherein the shell is provided with a groove, a pipeline inlet and a pipeline outlet, the pipeline inlet and the pipeline outlet are respectively communicated with the groove, and a pump rotor is arranged in the groove; the pump rotor is characterized by comprising a motor, a rotating base, a supporting frame and a roller; the motor is arranged in the shell and provided with a controlled end connected with an external controller, the rotating base is in transmission connection with the motor and is provided with a rotating axis, one end of the supporting frame is hinged with the rotating base, the other end of the supporting frame is in rotating connection with the roller, and a gap for the guide pipe to pass through is reserved between the roller and the side wall of the groove; an elastic buffer part is arranged between the rotating base and the supporting frame.
In the structure, the roller wheel arranged on the support frame is used for extruding the catheter, the gap between the roller wheel and the side wall of the groove is matched with the diameter of the catheter of the left heart auxiliary device, and the rotating speed of a pump rotor motor can be adjusted to meet the requirement of larger blood pumping volume of the left heart auxiliary device; however, the problem that the amplitude of the pulse pressure change becomes larger is generated, and for the problem, the structure mainly adopts the following solving means: a buffer structure which can be adjusted along with the extrusion pressure is formed between the support frame and the base through the hinge structure and the elastic buffer piece, so that the range of the output pulse pressure is narrowed, and the pulse pressure can be always in the acceptable degree of a human body.
The technical scheme of the invention is further perfected as follows:
preferably, the number of the support frames is two, the number of the idler wheels is two, the support frames correspond to the idler wheels one by one, and the idler wheels are rotatably connected with the other ends of the corresponding support frames; the supporting frame and the rollers are respectively distributed on two sides of the rotating base and are respectively in central symmetry with respect to the rotating axis of the rotating base; the elastic buffer parts are two and correspond to the support frames one by one, and are respectively positioned between the corresponding support frames and the rotating base.
More preferably, the support frames are a first support frame and a second support frame, the rollers are a first roller and a second roller, the first roller is rotatably connected with the other end of the first support frame, and the second roller is rotatably connected with the other end of the second support frame; the first support frame and the first idler wheel are positioned on one side of the rotating base, and the second support frame and the second idler wheel are positioned on the other side of the rotating base; one end of the rotating base is provided with a first connecting column at one side, and the other end of the rotating base is provided with a second connecting column at the other side; one end of the first support frame is hinged with a first connecting column of the rotating base, and one end of the second support frame is hinged with a second connecting column of the rotating base; the elastic buffer part is a first elastic part and a second elastic part, the first elastic part is positioned between one side of the rotating base and the first support frame, and the second elastic part is positioned between the other side of the rotating base and the second support frame.
By adopting the preferable scheme, the specific structure of the pump rotor can be further optimized, so that a more stable blood pumping effect can be realized.
Preferably, rotating base is equipped with the telescopic machanism that corresponds with the support frame, telescopic machanism's output is flexible member, the clamp plate has been set firmly in the circumference of flexible member, the end of flexible member is equipped with the slot hole, the support frame is equipped with the accommodation space that supplies flexible member to penetrate, the support frame is equipped with the pin that passes the slot hole in its accommodation space, the circumference of flexible member is located to the elastic buffer cover, elastic buffer's one end links firmly or looks butt with the clamp plate, and its other end links firmly or looks butt with the support frame.
More preferably, the telescoping mechanism has a controlled end connected to an external controller; the telescopic mechanism is provided with a pressure sensor, and the signal output end of the pressure sensor is connected with an external controller; the long hole of the telescopic rod piece extends along the telescopic direction of the telescopic rod piece.
By adopting the above preferred scheme, the basic position of the roller can be further adjusted through the telescopic mechanism, so that the extrusion force of the roller on the guide pipe is increased or reduced, the output pulse pressure range of the pump body can be adjusted more directly, the output pulse pressure range of the pump body can be controlled within the acceptable degree of a human body more easily, and the output of a proper pulse pressure range can be realized according to the specific blood pressure conditions of different patients. The support frame can keep a certain buffer displacement amount through the matching of the long hole and the pin and the buffer action of the elastic buffer piece, so that the catheter can be more gently and gradually extruded to be flattest when the roller turns into the catheter extrusion area, and the blood pumping flow is more stable; the pressure sensor of the telescopic mechanism can provide a pressure signal for an external controller, and better monitoring and controlling effects can be realized.
Preferably, the rotating base is further provided with auxiliary rollers, and the auxiliary rollers correspond to the supporting frames one by one; the rotating base is provided with an accommodating groove, and the accommodating groove is provided with at least one vertical guide pillar; the auxiliary roller comprises a roller and a roller, the roller is rotatably connected with one end of the roller, and the other end of the roller is sleeved on the periphery of the guide pillar and forms a moving pair with the guide pillar; the guide post is also provided with an elastic reset piece positioned below the rolling shaft in the circumferential direction; the support frame is provided with a space for the rolling shaft to pass through.
More preferably, the secondary roller has a supporting state for supporting the conduit pressed by the roller to restore its shape by the elastic restoring member.
By adopting the preferable scheme, the action structure of the pump rotor on the catheter can be further optimized, the auxiliary roller has a supporting effect on the catheter under the action of the elastic reset piece, the shape of the catheter extruded by the roller can be quickly restored, the catheter does not need to completely depend on the elasticity of the catheter, and the catheter can be quickly filled with blood after being extruded so as to be prepared for the next time of extruding the blood by the roller and further play a role in stabilizing the flow of the blood pump.
Preferably, the shell is provided with a transparent flip cover, one end of the flip cover is hinged with the shell, and the other end of the flip cover is attracted with the shell through a magnetic attraction device; the rotating base is provided with a rotation detection sensor, and the shell is also provided with an uncovering protection sensor and an ultrasonic bubble detector; the pipeline inlet and the pipeline outlet are respectively provided with a pipe clamp assembly; and the signal output ends of the rotation detection sensor, the cover opening protection sensor and the ultrasonic bubble detector are respectively connected with an external controller.
By adopting the preferred scheme, the rest specific structures of the peristaltic pump can be further optimized. Wherein, the rotation detection sensor can detect whether the pump rotor operates; the cover opening protection sensor can detect whether the turnover cover is opened or not, and if the turnover cover is opened, the pump rotor motor is closed by the controller; the ultrasonic bubble detector can monitor whether bubbles exist in liquid in the pipeline or not, if the bubbles are detected, the controller closes the pump rotor motor and emits a bubble discharge warning to avoid serious complications; the clamp assembly may assist in positioning the pipe.
The invention also proposes:
an in vitro left heart assist device system comprises a controller and a power source; the peristaltic pump is characterized by further comprising an input pipe, an output pipe and a peristaltic pipe, wherein one end of the peristaltic pipe is communicated with the input pipe, and the other end of the peristaltic pipe is communicated with the output pipe; the power source is the peristaltic pump special for treating the heart failure; in the peristaltic pump, the peristaltic pipe penetrates through the inlet of the pipeline, passes through a gap between the roller and the side wall of the groove and penetrates out of the outlet of the pipeline; the input pipe is positioned at the input side of the peristaltic pump, and the output pipe is positioned at the output side of the peristaltic pump; the controlled end of the peristaltic pump motor is connected with the control end of the controller; the peristaltic tube is provided with an output pressure sensor at the output side of the peristaltic pump, or the output tube is provided with an output pressure sensor, and the signal output end of the output pressure sensor is connected with the signal input end of the controller.
When the in-vitro left heart auxiliary device system is implemented, the front end of an input tube is arranged in the left atrium of a patient through a femoral vein, the front end of an output tube is arranged in the aorta of the patient through a femoral artery, and the input tube and the output tube are transited through a peristaltic tube; the peristaltic pump is arranged outside the body of the patient to provide a power source, so that the left heart auxiliary function is realized. Only the input tube, the output tube and the peristaltic tube contact blood, but the peristaltic pump does not contact blood, and only all the pipelines need to be removed after the treatment of a patient is finished, so that the long-term complication incidence rate is low; meanwhile, the disposable consumables in the treatment scheme only comprise the input tube, the output tube and the peristaltic tube, and the peristaltic pump can be repeatedly used, so that the treatment cost is greatly reduced, and the delayed heart failure treatment can be repeatedly developed. In addition, by adjusting the blood flow rate, the in vitro left heart auxiliary device system can be applied to various clinical scenes such as chronic heart failure, acute heart failure, pericardial tamponade treatment and the like.
The invention also proposes:
the control method of the in vitro left heart assist device system is characterized by comprising a calibration step, or comprising the calibration step and a control step;
calibrating step, calibrating the peristaltic pump; the calibration process comprises the following steps:
s1, connecting an output pipe with a flowmeter, connecting a signal output end of the flowmeter with a controller, adjusting the rotating speed of the peristaltic pump by the controller to enable the pump flow to reach a preset flow value, and taking the rotating speed of the peristaltic pump at the moment as a calibration rotating speed;
s2, controlling the rotation speed of the peristaltic pump to be at a calibration rotation speed by the controller, controlling the telescopic mechanism to gradually adjust the telescopic amount by the controller, monitoring the maximum pressure of the telescopic mechanism and the maximum output pressure of the peristaltic pump under different telescopic amounts, and fitting according to the data to obtain a relation function between the maximum pressure of the telescopic mechanism and the maximum output pressure of the peristaltic pump;
s3, calculating the maximum pressure limit value of the telescopic mechanism according to the relation function according to the preset output pressure limit value of the peristaltic pump by the controller; finishing calibration;
the controller controls the rotation speed of the peristaltic pump to be in a calibrated rotation speed, and controls the telescopic mechanism to adjust the telescopic amount so that the maximum pressure of the telescopic mechanism is kept below the maximum pressure limit value of the telescopic mechanism.
The control method can implement calibration steps before or in the middle of the first use of the in-vitro left heart auxiliary device system when the preset flow value needs to be changed so as to determine the control parameters, and then the peristaltic pump is controlled according to the control parameters, so that the pulse pressure can be ensured to be always in the acceptable degree of a target patient.
Compared with the prior art, the peristaltic pump special for treating heart failure has the advantages that the output pulse pressure range is suitable for the acceptable degree of a human body, and the requirement of serving as a power source of a left heart auxiliary device can be met; the left heart auxiliary device system can effectively realize the left heart auxiliary function, has low long-term complication incidence rate, greatly reduces the treatment cost compared with the prior treatment scheme, and can be suitable for various clinical scenes such as chronic heart failure, acute heart failure, pericardium stuffing treatment and the like.
Drawings
Fig. 1 is an overall schematic view of embodiment 1 of the present invention.
Fig. 2 is a schematic front perspective view of embodiment 1 of the present invention.
Fig. 3 is a schematic view of a pump rotor according to embodiment 1 of the present invention.
Fig. 4 is an enlarged perspective view of the area a of fig. 3 with respect to the telescopic mechanism.
Fig. 5 is an enlarged perspective view of the region B of fig. 3 with respect to the secondary roller.
Fig. 6 is a cross-sectional view of the secondary roller at view C-C of fig. 5.
Fig. 7 is an electrical connection diagram of embodiment 1 of the present invention.
Fig. 8 is an electrical connection diagram according to embodiment 2 of the present invention.
Detailed Description
The invention is described in further detail below with reference to embodiments and with reference to the drawings. The invention is not limited to the examples given.
Example 1
As shown in fig. 1 to 7, the peristaltic pump for treating heart failure of the present embodiment includes a housing 01, the housing 01 has a groove 02, a tube inlet 03 and a tube outlet 04, the tube inlet 03 and the tube outlet 04 are respectively communicated with the groove 02, and a pump rotor is disposed in the groove 02; the pump rotor comprises a motor, a rotating base 05, a support frame 06 and a roller 07; the motor is arranged in the shell 01, the motor is provided with a controlled end connected with an external controller, the rotating base 05 is in transmission connection with the motor, the rotating base 05 is provided with a rotating axis, one end of the support frame 06 is hinged with the rotating base 05, the other end of the support frame 06 is in rotating connection with the roller 07, and a gap for the guide pipe to pass through is reserved between the roller 07 and the side wall of the groove 02; an elastic buffer 08 (e.g., a spring) is disposed between the rotating base 05 and the supporting frame 06.
Specifically, two support frames 06 are provided, two idler wheels 07 are provided, the support frames 06 correspond to the idler wheels 07 one by one, and the idler wheels 07 are rotatably connected with the other ends of the corresponding support frames 06; the support frame 06 and the rollers 07 are respectively distributed on two sides of the rotating base 05 and are respectively symmetrical about the center of the rotating axis of the rotating base 05; the two elastic buffer members 08 are in one-to-one correspondence with the support frames 06, and are respectively located between the corresponding support frame 06 and the rotating base 05.
As shown in fig. 3, the support frames 06 are a first support frame 09 and a second support frame 10, the rollers 07 are a first roller 11 and a second roller 12, the first roller 11 is rotatably connected with the other end of the first support frame 09, and the second roller 12 is rotatably connected with the other end of the second support frame 10; the first support frame 09 and the first roller 11 are positioned on one side of the rotating base 05, and the second support frame 10 and the second roller 12 are positioned on the other side of the rotating base 05; one end of the rotating base 05 is provided with a first connecting column 13 at one side thereof, and the other end of the rotating base 05 is provided with a second connecting column 14 at the other side thereof; one end of the first support frame 09 is hinged with the first connecting column 13 of the rotating base 05, and one end of the second support frame 10 is hinged with the second connecting column 14 of the rotating base 05; the elastic buffer 08 is a first elastic element 15 and a second elastic element 16, the first elastic element 15 is located between one side of the rotating base 05 and the first support frame 09, and the second elastic element 16 is located between the other side of the rotating base 05 and the second support frame 10.
Specifically, as shown in fig. 4, the rotating base 05 is provided with a telescopic mechanism 17 corresponding to the support frame 06, an output end of the telescopic mechanism 17 is a telescopic rod 18, a pressing plate 19 is fixedly arranged on the circumference of the telescopic rod 18, a long hole 20 is arranged at the end of the telescopic rod 18, the support frame 06 is provided with an accommodating space 21 for the telescopic rod 18 to penetrate, a pin 22 penetrating through the long hole 20 is arranged in the accommodating space 21 of the support frame 06, an elastic buffer 08 is sleeved on the circumference of the telescopic rod 18, one end of the elastic buffer 08 is fixedly connected or abutted to the pressing plate 19, and the other end of the elastic buffer 08 is fixedly connected or abutted to the support frame 06. The telescopic mechanism 17 has a controlled end connected with an external controller; the telescopic mechanism 17 is provided with a pressure sensor, and the signal output end of the pressure sensor is connected with an external controller; the elongated hole 20 of the telescopic link 18 extends in the telescopic direction of the telescopic link 18.
Note: the telescopic mechanism 17 may be a hydraulic oil pump and its driving hydraulic rod (using hydraulic rod as telescopic rod 18), a stepping motor and its driving screw (using screw as telescopic rod 18), etc. existing structures.
Specifically, as shown in fig. 3, 5 and 6, the rotating base 05 is further provided with auxiliary rollers 23, and the auxiliary rollers 23 correspond to the support frame 06 one by one; the rotating base 05 is provided with a receiving groove 24, and the receiving groove 24 is provided with at least one vertical guide post 25 (two in this embodiment); the auxiliary roller 23 comprises a roller 26 and a roller 27, the roller 27 is rotatably connected with one end of the roller 26, and the other end of the roller 26 is sleeved on the periphery of the guide post 25 and forms a moving pair with the guide post 25; the guide post 25 is also provided with an elastic return element 28 (e.g. a spring) circumferentially below the roller 26; the support frame 06 has a space through which the roller 26 passes. The secondary roller 23 has a supporting state for supporting the conduit pressed by the roller 07 to restore its shape by an elastic restoring member 28.
In addition, the shell 01 is provided with a transparent flip 29, one end of the flip 29 is hinged with the shell 01, and the other end of the flip 29 is attracted with the shell 01 through a magnetic attraction device 30; the rotary base 05 is provided with a rotation detection sensor 32 (such as a hall sensor and a corresponding magnet), and the shell 01 is also provided with an uncovering protection sensor 33 (such as a hall sensor and a corresponding magnet) and an ultrasonic bubble detector; the pipe inlet 03 and the pipe outlet 04 are respectively provided with a pipe clamp assembly 31. The signal output ends of the rotation detection sensor, the cover opening protection sensor and the ultrasonic bubble detector are respectively connected with an external controller. Note: the ultrasonic bubble detector can adopt bubble and liquid detectors produced by Sinonsonic ultrasonic, Dongfangjinglong.
The peristaltic pump special for treating heart failure in the embodiment has the highest pumping capacity of 1.5L/min, which is 3 times of the highest pumping capacity (500ml/min) of the existing dialysis medical peristaltic pump, and can meet the pumping capacity requirement of the left heart auxiliary device and enable the output pulse pressure range to be suitable for the acceptable degree of a human body.
It should be noted that: the peristaltic pump special for treating heart failure mainly has the function of partially replacing the heart blood pumping, so that when an accident (such as air bubble detection) occurs, the peristaltic pump can be temporarily stopped to perform emergency treatment so as to prevent serious complications, the current cardiac output of a patient cannot be influenced, and the patient cannot die due to the temporary stop of the pump body. Therefore, the peristaltic pump special for treating heart failure can further improve the safety of LVAD treatment.
Example 2
The extracorporeal left heart assist device system of the embodiment includes a controller, a power source, an input tube, an output tube, and a peristaltic tube, wherein one end of the peristaltic tube is communicated with the input tube and the other end of the peristaltic tube is communicated with the output tube; the power source is the peristaltic pump special for treating the heart failure in the embodiment 1; in the peristaltic pump, a peristaltic pipe penetrates through a pipeline inlet, passes through a gap between a roller and the side wall of the groove and penetrates out of a pipeline outlet; the input pipe is positioned at the input side of the peristaltic pump, and the output pipe is positioned at the output side of the peristaltic pump; the controlled end of the peristaltic pump motor is connected with the control end of the controller, and the signal output end of the telescopic mechanism pressure sensor is connected with the signal input end of the controller; the peristaltic tube is provided with an output pressure sensor at the output side of the peristaltic pump, or the output tube is provided with an output pressure sensor, and the signal output end of the output pressure sensor is connected with the signal input end of the controller. The electrical connection scheme is shown in fig. 8. In addition, the signal output ends of the rotation detection sensor, the cover opening protection sensor and the ultrasonic bubble detector of the peristaltic pump are respectively connected with the controller.
When the device is used, the front end of the input tube is arranged in the left atrium of a patient through a femoral vein, the front end of the output tube is arranged in the aorta of the patient through a femoral artery, and the input tube and the output tube are transited through a peristaltic tube; the peristaltic pump is arranged outside the body of the patient to provide a power source, so that the left heart auxiliary function is realized. The blood oxygenated by the left atrium can be pumped into the main artery by the driving action of the peristaltic pump, so that the workload of the left ventricle is reduced, the perfusion of main organs such as kidneys and the like is improved, and the symptoms of patients with heart failure are improved; after the treatment is finished, all the pipelines are removed from the human body.
Example 3
The embodiment is a control method of the in vitro left heart assist device system of embodiment 2, comprising a calibration step, or comprising a calibration step and a control step;
calibrating step, calibrating the peristaltic pump; the calibration process comprises the following steps:
s1, connecting an output pipe with a flowmeter, connecting a signal output end of the flowmeter with a controller, adjusting the rotating speed of the peristaltic pump by the controller to enable the pump flow to reach a preset flow value, and taking the rotating speed of the peristaltic pump at the moment as a calibration rotating speed;
s2, controlling the rotation speed of the peristaltic pump to be at a calibration rotation speed by the controller, controlling the telescopic mechanism to gradually adjust the telescopic amount by the controller, monitoring the maximum pressure of the telescopic mechanism and the maximum output pressure of the peristaltic pump under different telescopic amounts, and fitting according to the data to obtain a relation function between the maximum pressure of the telescopic mechanism and the maximum output pressure of the peristaltic pump;
s3, calculating the maximum pressure limit value of the telescopic mechanism according to the relation function according to the preset output pressure limit value of the peristaltic pump by the controller; finishing calibration;
the controller controls the rotation speed of the peristaltic pump to be in a calibrated rotation speed, and controls the telescopic mechanism to adjust the telescopic amount so that the maximum pressure of the telescopic mechanism is kept below the maximum pressure limit value of the telescopic mechanism.
The embodiment can implement calibration steps before or in the middle of the first use of the in-vitro left heart auxiliary device system when the preset flow value needs to be changed so as to determine the control parameters, and then the peristaltic pump is controlled according to the control parameters, so that the pulse pressure can be ensured to be always in the acceptable degree of the target patient.
In addition to the above embodiments, the present invention may have other embodiments. All technical solutions formed by adopting equivalent substitutions or equivalent transformations fall within the protection scope of the claims of the present invention.

Claims (10)

1. A peristaltic pump special for treating heart failure comprises a shell, wherein the shell is provided with a groove, a pipeline inlet and a pipeline outlet, the pipeline inlet and the pipeline outlet are respectively communicated with the groove, and a pump rotor is arranged in the groove; the pump rotor is characterized by comprising a motor, a rotating base, a supporting frame and a roller; the motor is arranged in the shell and provided with a controlled end connected with an external controller, the rotating base is in transmission connection with the motor and is provided with a rotating axis, one end of the supporting frame is hinged with the rotating base, the other end of the supporting frame is in rotating connection with the roller, and a gap for the guide pipe to pass through is reserved between the roller and the side wall of the groove; an elastic buffer part is arranged between the rotating base and the supporting frame.
2. The peristaltic pump special for treating heart failure as claimed in claim 1, wherein there are two support frames, there are two rollers, the support frames correspond to the rollers one by one, and the rollers are rotatably connected to the other ends of the corresponding support frames; the supporting frame and the rollers are respectively distributed on two sides of the rotating base and are respectively in central symmetry with respect to the rotating axis of the rotating base; the elastic buffer parts are two and correspond to the support frames one by one, and are respectively positioned between the corresponding support frames and the rotating base.
3. The peristaltic pump as claimed in claim 2, wherein the support frame is a first support frame and a second support frame, the rollers are a first roller and a second roller, the first roller is rotatably connected to the other end of the first support frame, and the second roller is rotatably connected to the other end of the second support frame; the first support frame and the first idler wheel are positioned on one side of the rotating base, and the second support frame and the second idler wheel are positioned on the other side of the rotating base; one end of the rotating base is provided with a first connecting column at one side, and the other end of the rotating base is provided with a second connecting column at the other side; one end of the first support frame is hinged with a first connecting column of the rotating base, and one end of the second support frame is hinged with a second connecting column of the rotating base; the elastic buffer part is a first elastic part and a second elastic part, the first elastic part is positioned between one side of the rotating base and the first support frame, and the second elastic part is positioned between the other side of the rotating base and the second support frame.
4. The peristaltic pump for treating heart failure as claimed in claim 1, wherein the rotary base has a telescopic mechanism corresponding to the support frame, the output end of the telescopic mechanism is a telescopic rod, the circumference of the telescopic rod is fixedly provided with a pressing plate, the end of the telescopic rod is provided with a long hole, the support frame is provided with an accommodating space for the telescopic rod to penetrate, the support frame is provided with a pin passing through the long hole in the accommodating space, the elastic buffer member is sleeved on the circumference of the telescopic rod, one end of the elastic buffer member is fixedly connected or abutted to the pressing plate, and the other end of the elastic buffer member is fixedly connected or abutted to the support frame.
5. The peristaltic pump of claim 4, wherein the telescoping mechanism has a controlled end connected to an external controller; the telescopic mechanism is provided with a pressure sensor, and the signal output end of the pressure sensor is connected with an external controller; the long hole of the telescopic rod piece extends along the telescopic direction of the telescopic rod piece.
6. The peristaltic pump special for treating heart failure as claimed in claim 1, wherein the rotary base is further provided with auxiliary rollers, and the auxiliary rollers are in one-to-one correspondence with the supporting frames; the rotating base is provided with an accommodating groove, and the accommodating groove is provided with at least one vertical guide pillar; the auxiliary roller comprises a roller and a roller, the roller is rotatably connected with one end of the roller, and the other end of the roller is sleeved on the periphery of the guide pillar and forms a moving pair with the guide pillar; the guide post is also provided with an elastic reset piece positioned below the rolling shaft in the circumferential direction; the support frame is provided with a space for the rolling shaft to pass through.
7. The peristaltic pump as claimed in claim 6, wherein the auxiliary roller has a supporting state for supporting the catheter pressed by the roller to restore its shape under the action of the elastic restoring member.
8. The peristaltic pump as claimed in any one of claims 1 to 7, wherein the housing has a transparent cover, one end of the cover is hinged to the housing, and the other end of the cover is attracted to the housing by a magnetic attraction device; the rotating base is provided with a rotation detection sensor, and the shell is also provided with an uncovering protection sensor and an ultrasonic bubble detector; the pipeline inlet and the pipeline outlet are respectively provided with a pipe clamp assembly; and the signal output ends of the rotation detection sensor, the cover opening protection sensor and the ultrasonic bubble detector are respectively connected with an external controller.
9. An in vitro left heart auxiliary device system comprises a controller, a power source and a diversion catheter; the peristaltic pump is characterized by further comprising an input pipe, an output pipe and a peristaltic pipe, wherein one end of the peristaltic pipe is communicated with the input pipe, and the other end of the peristaltic pipe is communicated with the output pipe; the power source is the peristaltic pump special for treating the heart failure as claimed in any one of claims 1 to 8; in the peristaltic pump, the peristaltic pipe penetrates through the inlet of the pipeline, passes through a gap between the roller and the side wall of the groove and penetrates out of the outlet of the pipeline; the input pipe is positioned at the input side of the peristaltic pump, and the output pipe is positioned at the output side of the peristaltic pump; the controlled end of the peristaltic pump motor is connected with the control end of the controller; the peristaltic tube is provided with an output pressure sensor at the output side of the peristaltic pump, or the output tube is provided with an output pressure sensor, and the signal output end of the output pressure sensor is connected with the signal input end of the controller.
10. The method of controlling an extracorporeal left heart assist device system of claim 9, comprising a calibration step, or comprising a calibration step and a control step;
calibrating step, calibrating the peristaltic pump; the calibration process comprises the following steps:
s1, connecting an output pipe with a flowmeter, connecting a signal output end of the flowmeter with a controller, adjusting the rotating speed of the peristaltic pump by the controller to enable the pump flow to reach a preset flow value, and taking the rotating speed of the peristaltic pump at the moment as a calibration rotating speed;
s2, controlling the rotation speed of the peristaltic pump to be at a calibration rotation speed by the controller, controlling the telescopic mechanism to gradually adjust the telescopic amount by the controller, monitoring the maximum pressure of the telescopic mechanism and the maximum output pressure of the peristaltic pump under different telescopic amounts, and fitting according to the data to obtain a relation function between the maximum pressure of the telescopic mechanism and the maximum output pressure of the peristaltic pump;
s3, calculating the maximum pressure limit value of the telescopic mechanism according to the relation function according to the preset output pressure limit value of the peristaltic pump by the controller; finishing calibration;
the controller controls the rotation speed of the peristaltic pump to be in a calibrated rotation speed, and controls the telescopic mechanism to adjust the telescopic amount so that the maximum pressure of the telescopic mechanism is kept below the maximum pressure limit value of the telescopic mechanism.
CN202110808997.3A 2021-07-16 2021-07-16 Peristaltic pump special for treating heart failure and in-vitro left heart auxiliary device system thereof Withdrawn CN113521528A (en)

Priority Applications (2)

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CN202110808997.3A CN113521528A (en) 2021-07-16 2021-07-16 Peristaltic pump special for treating heart failure and in-vitro left heart auxiliary device system thereof
CN202210393049.2A CN114668966A (en) 2021-07-16 2022-04-14 In-vitro left heart auxiliary system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110808997.3A CN113521528A (en) 2021-07-16 2021-07-16 Peristaltic pump special for treating heart failure and in-vitro left heart auxiliary device system thereof

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CN202210393049.2A Pending CN114668966A (en) 2021-07-16 2022-04-14 In-vitro left heart auxiliary system

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