CN113520359A - Radial artery blood pressure value optimization method and device - Google Patents
Radial artery blood pressure value optimization method and device Download PDFInfo
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- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
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- A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
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Abstract
The invention discloses a method and a device for optimizing a radial artery blood pressure value, wherein the method comprises the following steps: acquiring pulse wave signals of a plurality of channels in the thin film type array sensor at the radial artery of the wrist according to the thin film type array sensor and the pressure device; fitting and synthesizing Gaussian curves according to envelope lines determined by the pulse wave signals in the channels to obtain expectation, highest points and standard deviations of the Gaussian curves; determining an optimal channel according to the expectation, the highest point and the preset standard deviation condition; and acquiring a systolic pressure value in the optimal channel according to the expected sampling time determined by the standard deviation and the standard deviation, and acquiring a diastolic pressure value of the optimal channel according to the sampling time determined by calculating a second derivative value of the Gaussian curve. According to the invention, the pulse wave signals are acquired by the film type array sensor and pressurized by the pressure device, the optimal channel and the systolic pressure value and the diastolic pressure value of the channel are screened, and the accuracy and the efficiency of acquiring the blood pressure value are improved.
Description
Technical Field
The invention relates to the technical field of blood pressure measurement, in particular to a method and a device for optimizing a radial artery blood pressure value.
Background
The existing device for testing the blood pressure of the radial artery is generally based on an oscillometric method, pressurization is carried out through an air bag surrounding the wrist, then pulse wave amplitude in the pressurization process is collected through an air pressure sensor, a wrapping line is drawn, and finally values of systolic pressure and diastolic pressure are estimated through a waveform feature method or an amplitude coefficient method.
The existing method for acquiring the radial artery blood pressure by acquiring the comprehensive signals in the air bag through the air pressure sensor cannot acquire local radial artery signals on the wrist, so that the blocking condition of the radial artery at the position with the best stress transmission effect cannot be acquired, and accurate radial artery systolic pressure cannot be directly acquired.
The conventional patent application number CN 112998676A discloses a continuous blood pressure measurement method based on multi-feature extraction of a photoelectric array enhanced signal, which can acquire abundant volume wave information, but the continuous blood pressure measurement method based on multi-feature extraction of the photoelectric array enhanced signal requires calibration of a standard sphygmomanometer to obtain an accurate blood pressure value, so that continuous blood pressure data can be estimated and acquired, and a plurality of instruments are required for measurement and calibration, so that the accuracy is not high.
Disclosure of Invention
The invention aims to provide a radial artery blood pressure value optimization method and a radial artery blood pressure value optimization device to solve the problem of low accuracy of obtaining a radial artery blood pressure value.
To achieve the above object, the present invention provides a preferred radial artery blood pressure value, comprising:
acquiring pulse wave signals of a plurality of channels in the thin film type array sensor at the radial artery of the wrist according to the thin film type array sensor and the pressure device;
fitting a Gaussian curve according to envelope lines determined by the pulse wave signals in the channels to obtain the highest point, expectation and standard deviation of the Gaussian curve;
determining an optimal channel according to the expectation, the highest point and the preset standard deviation condition;
and acquiring a systolic pressure value in the optimal channel according to the expected sampling time determined by the standard deviation and the standard deviation, and acquiring a diastolic pressure value of the optimal channel according to the sampling time determined by calculating a second derivative value of the Gaussian curve.
Preferably, the envelope curves determined according to the pulse wave signals in the channels are respectively fitted to form a gaussian curve f (x) as follows:
(x) a1 exp ((((x- μ)/σ) ^ 2)/2) where a1 represents the highest point, μ represents the expectation, and σ represents the standard deviation.
Preferably, the determining an optimal channel according to the preset conditions of the expectation, the highest point and the standard deviation includes: the desired screening condition;
acquiring the expected screening condition according to the pulse taking time d1 at which the maximum pressure value of the pressure device is located, the expected mu and the standard deviation sigma, and as follows:
d1-2*σ≥μ≥2*σ；
and removing channels which do not meet the expected screening conditions to obtain a first screening result.
Preferably, the determining an optimal channel according to the preset conditions of the expectation, the highest point and the standard deviation further includes: screening conditions for the highest point;
obtaining the screening condition of the highest point according to the highest point a1, the starting point A of the envelope curve, the end point B of the envelope curve and the Gaussian function f (x), as follows:
a1≥2*f(A)；
a1≥2*f(B)；
A＝μ-2*σ；
B＝μ+2*σ；
and removing the channels which do not accord with the screening conditions of the highest point, and obtaining a second screening result.
Preferably, the determining an optimal channel according to the preset conditions of the expectation, the highest point and the standard deviation further includes: screening conditions for the standard deviation;
and determining the screening condition of the standard deviation according to the minimum standard deviation value of the Gaussian curve in the selected first screening result and the second screening result, and obtaining the optimal channel.
Preferably, the sampling time T1 determined according to the expectation and the standard deviation comprises:
T1＝μ+e1*σ；
wherein e1 represents a parameter value in the interval [1, 3], the systolic pressure value being determined from the pressure value at the sampling time T1.
Preferably, the sampling time T2 determined according to the calculation of the second derivative value of the gaussian curve includes:
and selecting an increasing function in the Gaussian curve, calculating a second derivative value of the increasing function, if the second derivative value is 0, acquiring a corresponding abscissa in the increasing function as the sampling time T2, and determining the diastolic pressure value according to the pressure value of the sampling time T2.
The invention also provides a radial artery blood pressure value optimizing device, which comprises:
the first acquisition module is used for acquiring pulse wave signals of a plurality of channels in the thin film type array sensor at the radial artery of the wrist according to the thin film type array sensor and the pressure device;
the second acquisition module is used for respectively fitting a Gaussian curve according to the envelope curve determined by the pulse wave signals in the channel to acquire the highest point, the expectation and the standard deviation of the Gaussian curve;
the determining module is used for determining an optimal channel according to the expectation, the highest point and the preset condition of the standard deviation;
and the calculation module is used for acquiring a systolic pressure value in the optimal channel according to the expected sampling time determined by the standard deviation and the standard deviation, and acquiring a diastolic pressure value of the optimal channel according to the sampling time determined by calculating the second derivative value of the Gaussian curve.
The invention also provides application of the radial artery blood pressure value optimization method in preparation of a medical sphygmomanometer, wherein the application comprises monitoring of blood pressure parameters.
The invention also provides a computer terminal device comprising one or more processors and a memory. A memory coupled to the processor for storing one or more programs; when executed by the one or more processors, cause the one or more processors to implement a preferred method of radial artery blood pressure values as described in any of the embodiments above.
The present invention also provides a computer-readable storage medium having stored thereon a computer program which, when executed by a processor, implements a radial artery blood pressure value preference method as described in any of the above embodiments.
The invention is applied to the field of medical health detection, is used for monitoring blood pressure parameters, combines the characteristics of an array type film pressure sensor and a pressure device, applies pressure by the pressure device, obtains pulse wave signals of a plurality of channels in the array type film pressure sensor, obtains an expectation, a peak and a standard deviation through Gaussian fitting, respectively sets screening conditions of the expectation, the peak and the standard deviation, determines an optimal channel, screens out an optimal systolic pressure value and an optimal diastolic pressure value of the channel, and improves the accuracy of obtaining the blood pressure value.
Drawings
In order to more clearly illustrate the technical solution of the present invention, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic flow chart of a preferred method for measuring radial artery blood pressure according to an embodiment of the present invention;
FIG. 2 is a graph of 12-channel pressurization provided by another embodiment of the present invention;
FIG. 3 is a graph of the pulse wave of each channel after filtering according to another embodiment of the present invention;
FIG. 4 is a graph of pulse wave and envelope fit for an optimal channel after filtering according to another embodiment of the present invention;
fig. 5 is a schematic structural diagram of a preferred device for measuring radial artery blood pressure according to an embodiment of the present invention.
Detailed Description
The technical solutions in the present invention will be described clearly and completely with reference to the accompanying drawings, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be understood that the step numbers used herein are for convenience of description only and are not used as limitations on the order in which the steps are performed.
It is to be understood that the terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in the specification of the present invention and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
The terms "comprises" and "comprising" indicate the presence of the described features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof.
The term "and/or" refers to and includes any and all possible combinations of one or more of the associated listed items.
Referring to fig. 1, the present invention provides a method for optimizing radial artery blood pressure, comprising:
s101, acquiring pulse wave signals of a plurality of channels in the thin film type array sensor at the radial artery of the wrist according to the thin film type array sensor and the pressure device.
Specifically, according to the blood pressure testing principle, when external pressure reaches the systolic pressure of a blood vessel, the blood vessel is blocked, pulse wave signals disappear, and considering that the wrist is irregular in shape and the pressure applied by the air bag at different positions is difficult to keep consistent, the blood vessel is blocked at first at a position with good stress transmission to reach the value of the systolic pressure, so that the sensor is required to obtain local accurate pulse wave signals and perform processing calculation.
The blood pressure value comprises a systolic pressure value and a diastolic pressure value, the film array sensor can be well attached to the wrist, detailed pulse wave signals and distribution in a certain area can be obtained by designing the number and arrangement distribution of channels of the sensing units, the size of the units can be smaller than the diameter (3mm) of the radial artery by the flexible design mode of the film array sensor, accurate pulse wave signals are ensured to be obtained, multi-channel pulse waves are filtered, and signals with the signal frequency within 0.5Hz-30Hz are reserved.
Referring to fig. 2 and 3, assuming that there are 12 channels, the pressurizing curves of the 12 channels are obtained, after filtering the multi-channel pulse waves, the pulse wave curves of the channels are obtained respectively, and then the optimal blood pressure value is calculated according to the highest point, the expectation and the standard deviation of each channel curve.
S102, fitting a Gaussian curve according to the envelope curve determined by the pulse wave signals in the channel to obtain the highest point, expectation and standard deviation of the Gaussian curve.
Specifically, envelope extraction is performed according to the pulse wave screened in step S101, a gaussian curve is fitted according to the envelope, the highest point, the expectation and the standard deviation of the gaussian curve are obtained according to the coordinate parameters of the gaussian curve, and the gaussian function of the gaussian curve is as follows:
f(x)＝a1*exp((-((x-μ)/σ)∧2)/2)；
where a1 represents the highest point of the gaussian curve, μ represents the expectation of the gaussian curve, and σ represents the standard deviation of the gaussian curve.
S103, determining an optimal channel according to the expectation, the highest point and the preset standard deviation condition.
Referring to fig. 4, specifically, the screening conditions of the highest point, the expectation and the standard deviation of the gaussian curve are respectively set as follows:
1) firstly, respectively screening the expectation of Gaussian curves of a plurality of channels, wherein the envelope curve should have a complete increasing and decreasing process in the whole pressurizing process, and acquiring expected screening conditions according to the sampling time d1 where the pressure maximum value of the pressure device is located, the expectation mu and the standard deviation sigma, wherein the expected screening conditions are as follows:
d1-2*σ≥μ≥2*σ；
and removing channels which do not meet expected screening conditions to obtain a first screening result.
2) Secondly, screening the highest point of the Gaussian curve, namely screening the highest amplitude of the pulse wave, removing channels with unobvious pulse wave amplitude increase, and obtaining the screening condition of the highest point according to the highest point a1, the abscissa A of the starting point of the envelope line, the abscissa B of the end point of the envelope line and a Gaussian function f (x), wherein the abscissa A is the same as the initial point of the envelope line, and the abscissa B is the same as the terminal point of the envelope line, and the Gaussian function f (x) is as follows:
a1≥2*f(A)；
a1≥2*f(B)；
A＝μ-2*σ；
B＝μ+2*σ；
and ensuring that the maximum amplitude of the pulse wave is more than twice of the amplitude when the pulse wave is at the lowest pressure and the highest pressure, and rejecting a channel which does not accord with the screening condition of the highest point to obtain a second screening result.
3) And finally, screening the standard deviation of the Gaussian curve, wherein the pulse wave amplitude is increased firstly and then reduced at a higher speed at the place with the best stress transmission effect, and selecting the Gaussian fitting curve with the smallest standard deviation of the envelope line as the optimal channel according to the first screening result and the second screening result.
Referring to fig. 3 and table 1, a film array sensor including twelve channels is selected, the highest point, the expectation and the standard deviation of each channel are respectively obtained, according to respective screening conditions, an optimal channel is selected first, then the blood pressure value of the channel is calculated, assuming that d1 is 30, the standard diastolic pressure obtained by a sphygmomanometer is 75mmHg, the systolic pressure is 115mmHg, as shown in table 1, the screening conditions of the expectation and the highest point are met, and then the channel with the smallest standard deviation of a gaussian fit curve of an envelope is selected as the optimal channel, that is, the standard deviation of the twelfth channel is 2.3 smallest, therefore, according to the selected twelfth channel, the diastolic pressure and the systolic pressure of the channel are calculated, as shown in table 1, the screening conditions are met, and otherwise, the channel is determined to be not met.
TABLE 1 comparison of priority data for each of twelve channels
And S104, acquiring a systolic pressure value in the optimal channel according to the expected sampling time determined by the standard deviation and the standard deviation, and acquiring a diastolic pressure value of the optimal channel according to the sampling time determined by calculating a second derivative value of the Gaussian curve.
Specifically, the pressure value of the thin film type array sensor unit at the sampling time T1 is taken as the systolic pressure value, as follows:
T1＝μ+e1*σ；
wherein e1 represents a parameter value in the interval [1, 3], and the pressure value of the thin film type array sensor unit at the sampling time T1 can be adjusted according to the actual situation (obesity degree, blood vessel depth, etc.).
Selecting an increasing function in the Gaussian curve, calculating a second-order derivative value of the increasing function, if the second-order derivative value is 0, acquiring a corresponding abscissa in the increasing function as sampling time T2, and determining the diastolic pressure value according to a pressure value of the sampling time T2.
The invention utilizes the characteristics of the array type film pressure sensor that the number, distribution and size of channels can be flexibly designed, combines a pressure device to obtain rich pulse wave information near the radial artery in the process of blood pressure test pressurization, and obtains the optimal blood pressure value by fitting pulse wave signals into a Gaussian curve, respectively setting the screening conditions of the highest point, expectation and variance in the Gaussian curve, and calculating the optimal channel and the optimal pulse wave of the channel according to the screening conditions, thereby obtaining the optimal blood pressure value and improving the accuracy of obtaining the blood pressure value.
Referring to fig. 5, the present invention provides a radial artery blood pressure optimizing device, including:
the first acquisition module 11 is used for acquiring pulse wave signals of a plurality of channels in the thin film type array sensor at the radial artery of the wrist according to the thin film type array sensor and the pressure device;
a second obtaining module 12, configured to respectively fit a gaussian curve according to the envelope determined by the pulse wave signal in the channel to which the pulse wave signal belongs, and obtain a highest point, an expectation, and a standard deviation of the gaussian curve;
a determining module 13, configured to determine an optimal channel according to the expected value, the highest point, and a preset condition of the standard deviation;
and the calculating module 14 is configured to obtain a systolic pressure value in the optimal channel according to the sampling time determined by the expectation and the standard deviation, and obtain a diastolic pressure value of the optimal channel according to the sampling time determined by calculating the second derivative value of the gaussian curve.
For the specific definition of the preferred device for the radial artery blood pressure value, reference may be made to the above definition, which is not described herein again. The modules in the above-mentioned radial artery blood pressure value optimization device can be realized by software, hardware and their combination in whole or in part. The modules can be embedded in a hardware form or independent from a processor in the computer device, and can also be stored in a memory in the computer device in a software form, so that the processor can call and execute operations corresponding to the modules.
The invention provides a computer terminal device comprising one or more processors and a memory. The memory is coupled to the processor for storing one or more programs which, when executed by the one or more processors, cause the one or more processors to implement the preferred method of radial artery blood pressure values as in any of the embodiments described above.
The processor is used for controlling the overall operation of the computer terminal device so as to complete all or part of the steps of the preferred method for measuring the radial artery blood pressure. The memory is used to store various types of data to support the operation at the computer terminal device, which data may include, for example, instructions for any application or method operating on the computer terminal device, as well as application-related data. The Memory may be implemented by any type of volatile or non-volatile Memory device or combination thereof, such as Static Random Access Memory (SRAM), Electrically Erasable Programmable Read-Only Memory (EEPROM), Erasable Programmable Read-Only Memory (EPROM), Programmable Read-Only Memory (PROM), Read-Only Memory (ROM), magnetic Memory, flash Memory, magnetic disk, or optical disk.
In an exemplary embodiment, the computer terminal Device may be implemented by one or more Application Specific 1 integrated circuits (AS 1C), a Digital Signal Processor (DSP), a Digital Signal Processing Device (DSPD), a Programmable Logic Device (PLD), a Field Programmable Gate Array (FPGA), a controller, a microcontroller, a microprocessor or other electronic components, and is configured to perform the above-mentioned radial artery blood pressure value optimization method and achieve the technical effects consistent with the above-mentioned methods.
In another exemplary embodiment, a computer readable storage medium is also provided that includes program instructions which, when executed by a processor, implement the steps of the radial artery blood pressure value preference method in any of the above embodiments. For example, the computer readable storage medium may be the memory described above comprising program instructions executable by the processor of the computer terminal device to perform the preferred method for radial artery blood pressure values described above and achieve a technical effect consistent with the method described above.
While the foregoing is directed to the preferred embodiment of the present invention, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the invention.
Claims (11)
1. A method for optimizing radial artery blood pressure values, comprising:
acquiring pulse wave signals of a plurality of channels in the thin film type array sensor at the radial artery of the wrist according to the thin film type array sensor and the pressure device;
fitting a Gaussian curve according to envelope lines determined by the pulse wave signals in the channels to obtain the highest point, expectation and standard deviation of the Gaussian curve;
determining an optimal channel according to the expectation, the highest point and the preset standard deviation condition;
and acquiring a systolic pressure value in the optimal channel according to the expected sampling time determined by the standard deviation and the standard deviation, and acquiring a diastolic pressure value of the optimal channel according to the sampling time determined by calculating a second derivative value of the Gaussian curve.
2. The method for optimizing radial artery blood pressure according to claim 1, wherein said envelope curves determined according to said pulse wave signals in said channels are respectively fitted to a gaussian curve f (x) as follows:
(x) a1 exp ((((x- μ)/σ) ^ 2)/2) where a1 represents the highest point, μ represents the expectation, and σ represents the standard deviation.
3. The method for optimizing radial artery blood pressure according to claim 2, wherein said determining an optimal path according to the condition preset by the expectation, the highest point and the standard deviation comprises: the desired screening condition;
acquiring the expected screening condition according to the pulse taking time d1 at which the maximum pressure value of the pressure device is located, the expected mu and the standard deviation sigma, and as follows:
d1-2*σ≥μ≥2*σ；
and removing channels which do not meet the expected screening conditions to obtain a first screening result.
4. The method of claim 3, wherein said determining an optimal path according to said expectation, said peak and said standard deviation preset conditions further comprises: screening conditions for the highest point;
obtaining the screening condition of the highest point according to the highest point a1, the starting point A of the envelope curve, the end point B of the envelope curve and the Gaussian function f (x), as follows:
a1≥2*f(A)；
a1≥2*f(B)；
A＝μ-2*σ；
B＝μ+2*σ；
and removing the channels which do not accord with the screening conditions of the highest point, and obtaining a second screening result.
5. The method of claim 4, wherein said determining an optimal path according to said expectation, said peak and said standard deviation preset conditions further comprises: screening conditions for the standard deviation;
and determining the screening condition of the standard deviation according to the minimum standard deviation value of the Gaussian curve in the selected first screening result and the second screening result, and obtaining the optimal channel.
6. The radial artery blood pressure value preference method of claim 5, wherein said sample time T1 determined according to said expectation and said standard deviation comprises:
T1＝μ+e1*σ；
wherein e1 represents a parameter value in the interval [1, 3], the systolic pressure value being determined from the pressure value at the sampling time T1.
7. The method for optimizing radial artery blood pressure according to claim 6, wherein the sampling time T2 determined according to calculating the second derivative value of the Gaussian curve comprises:
and selecting an increasing function in the Gaussian curve, calculating a second derivative value of the increasing function, if the second derivative value is 0, acquiring a corresponding abscissa in the increasing function as the sampling time T2, and determining the diastolic pressure value according to the pressure value of the sampling time T2.
8. A radial artery blood pressure value preference device, comprising:
the first acquisition module is used for acquiring pulse wave signals of a plurality of channels in the thin film type array sensor at the radial artery of the wrist according to the thin film type array sensor and the pressure device;
the second acquisition module is used for respectively fitting a Gaussian curve according to the envelope curve determined by the pulse wave signals in the channel to acquire the highest point, the expectation and the standard deviation of the Gaussian curve;
the determining module is used for determining an optimal channel according to the expectation, the highest point and the preset condition of the standard deviation;
and the calculation module is used for acquiring a systolic pressure value in the optimal channel according to the expected sampling time determined by the standard deviation and the standard deviation, and acquiring a diastolic pressure value of the optimal channel according to the sampling time determined by calculating the second derivative value of the Gaussian curve.
9. Use of a preferred method of radial artery blood pressure values according to any one of claims 1 to 7 in the manufacture of a medical sphygmomanometer, wherein the use comprises monitoring of blood pressure parameters.
10. A computer terminal device, comprising:
one or more processors;
a memory coupled to the processor for storing one or more programs;
when executed by the one or more processors, cause the one or more processors to implement a radial artery blood pressure value preferred method as claimed in any one of claims 1 to 7.
11. A computer-readable storage medium, on which a computer program is stored which, when being executed by a processor, carries out a radial artery blood pressure value preference method according to any one of claims 1 to 7.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6475154B1 (en) * | 2000-11-08 | 2002-11-05 | Taidoc Corp., Ltd. | Method and apparatus for non-invasive blood-pressure measurement |
| US20100113947A1 (en) * | 2008-11-06 | 2010-05-06 | Samsung Electronics Co., Ltd. | Apparatus and method of measuring blood pressure |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6475154B1 (en) * | 2000-11-08 | 2002-11-05 | Taidoc Corp., Ltd. | Method and apparatus for non-invasive blood-pressure measurement |
| US20100113947A1 (en) * | 2008-11-06 | 2010-05-06 | Samsung Electronics Co., Ltd. | Apparatus and method of measuring blood pressure |
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