CN113519503A - Isolated kidney perfusion apparatus for kidney transplantation - Google Patents
Isolated kidney perfusion apparatus for kidney transplantation Download PDFInfo
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- CN113519503A CN113519503A CN202110816912.6A CN202110816912A CN113519503A CN 113519503 A CN113519503 A CN 113519503A CN 202110816912 A CN202110816912 A CN 202110816912A CN 113519503 A CN113519503 A CN 113519503A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
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Abstract
The invention provides an isolated kidney perfusion apparatus for kidney transplantation, which relates to the field of isolated organ perfusion and aims to solve the problems that the height of an isolated kidney needs to be adjusted, and the kidney is damaged due to the fact that overflowing liquid is easy to remain to soak the isolated kidney during perfusion; the front end of the supporting mechanism is provided with a fixing mechanism; an installation mechanism is arranged above the contact mechanism; the rear end of the mounting mechanism is provided with a connecting mechanism; and the front end of the fixing mechanism is provided with a circulating mechanism and a collecting mechanism. Inside first circulation piece inputed the inside perfusate of stock solution spare into the kidney through the transfer pump, the imbibition pump of second circulation spare assisted the inside perfusate of second circulation spare suction kidney, inside the perfusate enters into the circular tube of second circulation spare, can press the pressure switch and move down, under the feedback of work piece, makes first circulation spare carry out the action of infusing next time.
Description
Technical Field
The invention belongs to the technical field of isolated organ perfusion, and particularly relates to an isolated kidney perfusion apparatus for kidney transplantation.
Background
The kidney transplantation technology is the most effective therapy in the end stage of kidney disease, and before the kidney transplantation, the isolated kidney needs to be preserved in a mechanical perfusion mode.
For example, application No.: CN201911404577.8 relates to an in vitro kidney perfusion system, which comprises a liquid delivery pipeline as a main body, a liquid inlet pipe, a liquid dropping funnel, a fluid speed regulation roller and an outflow assembly sequentially connected in series on the delivery pipeline, and the arrangement of the structure can make up the defects of inconvenience of a perfusion device used in the kidney transplantation process in the prior art, when multiple blood vessels or the blood vessels are thin, the simple device can be used for injecting medicine, the flow rate can be regulated by a pulley, the pressure can be generated during liquid conversion and extrusion by a soft ball, the perfusion is convenient, and a proper silicone tube can be selected for perfusion according to the thickness and the number of the renal artery, so that the perfusion system has the advantages of simple structure, wide material, convenient operation, low price, practicality, full perfusion and scientific and reasonable structure, the use is safe and convenient.
Based on prior art discovery, current separation kidney perfusion ware is when using, need adjust the height of separation kidney many times, take place the landing very easily and cause the destruction to the kidney, and the liquid that overflows when filling persists easily and leads to soaking the separation kidney and lead to the kidney to appear damaging, current separation kidney perfusion ware is when using simultaneously, needs the staff to adjust the frequency of filling, and is comparatively troublesome, prevents that too much or too few of perfusate from causing the damage to the separation kidney.
Disclosure of Invention
In order to solve the technical problems, the invention provides an in-vitro kidney perfusion apparatus for kidney transplantation, which is used for solving the problems that the height of an in-vitro kidney needs to be adjusted frequently when the existing in-vitro kidney perfusion apparatus is used, the kidney is easily damaged due to slipping, overflowing liquid is easily reserved during perfusion, the in-vitro kidney is soaked, the kidney is damaged, meanwhile, when the existing in-vitro kidney perfusion apparatus is used, a worker is required to adjust the perfusion frequency, the operation is troublesome, and the in-vitro kidney is prevented from being damaged due to too much or too little perfusion liquid.
The invention relates to an in vitro kidney perfusion apparatus for kidney transplantation, which is realized by the following specific technical means:
an ex vivo kidney perfusion apparatus for kidney transplantation, comprising:
a support mechanism;
a contact mechanism is arranged above the supporting mechanism, and a columnar bulge below the contact piece is inserted into the sealing cylinder; the front end of the supporting mechanism is provided with a fixing mechanism, and the fixing support is fixedly connected with the supporting box body through a screw; an installation mechanism is installed above the contact mechanism, and the T-shaped bulge of the installation plate is inserted into the T-shaped groove of the fixed support; the rear end of the mounting mechanism is provided with a connecting mechanism, and the connecting piece is connected with a conduit inside the mounting piece; the front end of the fixing mechanism is provided with a circulating mechanism and a collecting mechanism, and the first circulating piece and the second circulating piece are inserted into the fixing ring.
Further, the supporting mechanism comprises:
the supporting box body is of a rectangular structure, and a round-corner rectangular groove is formed in the rear end of the supporting box body; a circular through hole is formed in the right side of the supporting box body, and a rectangular bulge is formed in the front end of the supporting box body;
the rotating piece is of a circular structure, and a columnar bulge is arranged on the left side of the rotating piece; a gear is arranged on the left side of the columnar bulge of the rotating piece, and the columnar bulge of the rotating piece is inserted into the through hole of the supporting box body;
the sealing cylinder is a circular sleeve, the sealing cylinder is fixedly connected inside the supporting box body, and two circular through holes are formed in the bottom of the sealing cylinder.
Further, the supporting mechanism further comprises:
the one-way valve is inserted into the through hole at the bottom of the sealing cylinder;
the air release valve is inserted into the through hole of the sealing cylinder, and a sealing cover is arranged inside the air release valve.
Further, the contact mechanism includes:
the contact element is a rectangular box body, the lower surface of the interior of the contact element is a five-degree inclined plane, and the left side of the interior of the contact element is provided with a through hole; a columnar bulge is arranged below the contact element, and a sealing ring is arranged below the columnar bulge of the contact element;
the collecting box is a rectangular box body, and a fifteen-degree inclined plane is arranged below the collecting box; the collecting box is fixedly connected below the contact element and is communicated with the contact element through a through hole, and a liquid outlet is formed in the rear end of the collecting box;
the connecting plate is of an L-shaped plate-shaped structure and is fixedly connected below the contact element through screws; and a rack is arranged at the rear end of the connecting plate, and the rack of the connecting plate is meshed with a gear of a rotating part of the supporting mechanism.
Further, the fixing mechanism comprises:
the fixing support is a rectangular frame body, and the left side and the right side of the rear end of the fixing support are provided with T-shaped grooves;
the fixing rings are of L-shaped plate structures, circular through holes are formed in the fixing rings, and the two fixing rings are fixedly connected to the front end of the fixing support through screws;
and the workpiece is a control instrument and is fixedly connected to the front end of the fixing support through a screw.
Further, the installation mechanism includes:
the mounting plate is of a rectangular plate-shaped structure, and T-shaped bulges are arranged on the left side and the right side of the front end of the mounting plate; two rectangular bulges are arranged below the mounting plate, and two rotating shafts are arranged above the mounting plate;
the installed part, installed part are circular box, and the installed part is connected with the mounting panel through the pivot to installed part internally mounted has the pipe.
Further, the connecting mechanism comprises:
the connecting piece is of a metal tubular structure, four rectangular grooves are formed in the outer side above the connecting piece, and a metal needle is arranged below the connecting piece;
the fastener is of a circular structure, and four rectangular bulges are arranged inside the fastener; a circular through hole is formed below the fastener, and a metal needle of the connecting piece is inserted into the circular through hole of the fastener.
Further, the circulation mechanism includes:
the infusion pump is arranged above the first circulating piece, an infusion straw is arranged below the first circulating piece, and the first circulating piece is inserted into the fixing ring;
the liquid storage part is of a circular structure and is connected below the first circulating part through threads.
Further, the collection mechanism comprises:
a liquid suction pump is arranged above the second circulating piece, a round pipe is arranged below the second circulating piece, a rectangular through hole is formed in the left side of the second circulating piece, and the second circulating piece is inserted into the fixing ring;
the pressure switch is of a circular plate-shaped structure, and a spring is arranged below the pressure switch; the pressure switch is arranged inside the circular pipe of the second circulating piece, and the pressure switch and the circular pipe of the second circulating piece are sealed.
Further, the collecting mechanism further comprises:
the collecting cylinder is of a circular tubular structure, a rectangular through hole is formed in the right side of the collecting cylinder, and the rectangular through hole of the collecting cylinder is communicated with the rectangular through hole of the second circulating piece.
Compared with the prior art, the invention has the following beneficial effects:
1. in the device, a supporting mechanism is arranged, a one-way valve and an air release valve are arranged in a through hole below a sealing cylinder, a columnar bulge below a contact piece is sealed with the inside of the sealing cylinder when in use, the contact piece is lifted up through a rack of a connecting plate by rotating a rotating piece when in use, meanwhile, air can enter the sealing cylinder through the one-way valve under the driving of the columnar bulge of the contact element, thereby the contact piece can be supported by the air in the sealing cylinder and simultaneously buffered, thereby preventing the mechanism at the rising part from being damaged and falling down suddenly, the in vitro kidney inside the contact piece is damaged, when the contact piece needs to be put down, the air release valve can be opened, and the rotating piece is rotated to lead the contact piece to descend, during pouring, overflowing pouring liquid is collected through the contact element, flows into the through hole of the contact element along the inclined surface and is collected through the collecting box;
2. in the device, a circulating mechanism is arranged, when the isolated kidney needs to be filled, the isolated kidney is connected through a connecting mechanism, the metal needles of a connecting piece are respectively inserted into a liquid inlet and a liquid outlet of the kidney, and the connecting piece and the kidney are quickly fixed through a fastening piece, so that the device can be quickly connected with the isolated kidney, the trouble caused by suture and disconnection is avoided, meanwhile, under the control of a workpiece, a first circulating piece inputs the perfusion liquid in a liquid storage piece into the kidney through an infusion pump, meanwhile, a liquid suction pump of a second circulating piece is used for assisting the second circulating piece to suck out the perfusion liquid in the kidney, when the perfusion liquid enters into the round pipe below the second circulating piece, when the weight of the perfusion liquid reaches a certain degree, a pressure switch can be pressed to move downwards, and under the feedback of the workpiece, the first circulating piece carries out next infusion action, simultaneously the inside perfusate of the circular pipe of second circulation spare can enter into the collecting vessel through the rectangle through-hole inside, through above mechanism, can control the perfusion cycle to the separation kidney effectively, prevents that the inside perfusate of kidney from too much causing the influence to the kidney, or the perfusate makes less perfusion effect unobvious, has also avoided the staff to observe the trouble of organ constantly simultaneously.
Drawings
Fig. 1 is a schematic perspective view of the present invention.
Fig. 2 is a perspective view of the internal components of the present invention.
Fig. 3 is a rear view of the internal components of the present invention.
Fig. 4 is a schematic perspective sectional structure of the support mechanism of the present invention.
FIG. 5 is a perspective view of the mounting mechanism of the present invention.
Fig. 6 is a schematic perspective sectional structure of the circulation mechanism of the present invention.
Fig. 7 is a partially enlarged structural view at a shown in fig. 2 according to the present invention.
Fig. 8 is a partial enlarged structural view at B of fig. 2 according to the present invention.
In the drawings, the corresponding relationship between the component names and the reference numbers is as follows:
1. a support mechanism;
101. supporting the box body; 102. a rotating member; 103. a sealing cylinder; 104. a one-way valve; 105. a gas release valve;
2. a contact mechanism;
201. a contact member; 202. a collection box; 203. a connecting plate;
3. a fixing mechanism;
301. fixing a bracket; 302. a fixing ring; 303. a workpiece;
4. an installation mechanism;
401. mounting a plate; 402. a mounting member;
5. a connecting mechanism;
501. a connecting member; 502. a fastener;
6. a circulating mechanism;
601. a first circulating member; 602. a liquid storage member;
7. a collection mechanism;
701. a second circulating member; 702. a pressure switch; 703. and a collection cylinder.
Detailed Description
The embodiments of the present invention will be described in further detail with reference to the drawings and examples. The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.
In the description of the present invention, "a plurality" means two or more unless otherwise specified; the terms "upper", "lower", "left", "right", "inner", "outer", "front", "rear", "head", "tail", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are only for convenience in describing and simplifying the description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed in a particular orientation, and be operated, and thus, should not be construed as limiting the invention. Furthermore, the terms "first," "second," "third," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "connected" and "connected" are to be interpreted broadly, e.g., as being fixed or detachable or integrally connected; can be mechanically or electrically connected; may be directly connected or indirectly connected through an intermediate. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Example (b):
as shown in figures 1 to 8:
the invention provides an isolated kidney perfusion apparatus for kidney transplantation, which comprises: a supporting mechanism 1, wherein a contact mechanism 2 is arranged above the supporting mechanism 1, and a columnar bulge below a contact element 201 is inserted into the sealing cylinder 103; the front end of the supporting mechanism 1 is provided with a fixing mechanism 3, and the fixing bracket 301 is fixedly connected with the supporting box body 101 through screws; an installation mechanism 4 is installed above the contact mechanism 2, and the T-shaped bulge of the installation plate 401 is inserted into the T-shaped groove of the fixed bracket 301; the rear end of the mounting mechanism 4 is provided with a connecting mechanism 5, and the connecting piece 501 is connected with a conduit inside the mounting piece 402; the front end of the fixing mechanism 3 is mounted with a circulation mechanism 6 and a collection mechanism 7, and a first circulation piece 601 and a second circulation piece 701 are inserted inside the fixing ring 302.
Wherein, supporting mechanism 1 is including: the supporting box body 101 is of a rectangular structure, and a round-corner rectangular groove is formed in the rear end of the supporting box body 101; a circular through hole is formed in the right side of the supporting box body 101, and a rectangular bulge is formed in the front end of the supporting box body 101; the rotating part 102, the rotating part 102 is a circular structure, and a columnar bulge is arranged on the left side of the rotating part 102; a gear is arranged on the left side of the columnar bulge of the rotating piece 102, and the columnar bulge of the rotating piece 102 is inserted into the through hole of the supporting box body 101; the sealing cylinder 103 is a circular sleeve, the sealing cylinder 103 is fixedly connected inside the supporting box body 101, and the bottom of the sealing cylinder 103 is provided with two circular through holes; a check valve 104, the check valve 104 is inserted into the through hole at the bottom of the sealing cylinder 103; and an air release valve 105, the air release valve 105 being inserted inside the through hole of the sealing cylinder 103, and a sealing cover being installed inside the air release valve 105.
Wherein, contact mechanism 2 includes: the contact element 201 is a rectangular box body, the lower surface of the inside of the contact element 201 is a five-degree inclined plane, and the left side of the inside of the contact element 201 is provided with a through hole; a columnar bulge is arranged below the contact element 201, and a sealing ring is arranged below the columnar bulge of the contact element 201; the collecting box 202 is a rectangular box body, and a fifteen-degree inclined plane is arranged below the collecting box 202; the collecting box 202 is fixedly connected below the contact element 201, the collecting box 202 is communicated with the contact element 201 through a through hole, and a liquid outlet is formed in the rear end of the collecting box 202; the connecting plate 203 is of an L-shaped plate-shaped structure, and the connecting plate 203 is fixedly connected below the contact element 201 through screws; the rear end of the connecting plate 203 is provided with a rack, and the rack of the connecting plate 203 is meshed with the gear of the rotating member 102 of the supporting mechanism 1; during pouring, overflowing pouring liquid is collected through the contact element 201, flows into the through hole of the contact element 201 along the inclined surface, and is collected through the collection box 202; when the sealing device is used, the columnar bulge below the contact element 201 is sealed with the inside of the sealing cylinder 103, when the sealing device is used, the rotating element 102 is rotated, the contact element 201 is lifted through the rack of the connecting plate 203, meanwhile, air can enter the inside of the sealing cylinder 103 through the one-way valve 104 under the driving of the columnar bulge of the contact element 201, and then the contact element 201 can be supported by the air in the sealing cylinder 103.
Wherein, fixed establishment 3 is including: the fixing bracket 301 is a rectangular frame body, and the left side and the right side of the rear end of the fixing bracket 301 are provided with T-shaped grooves; the fixing rings 302 are L-shaped plate-shaped structures, circular through holes are formed in the fixing rings 302, and the two fixing rings 302 are fixedly connected to the front end of the fixing support 301 through screws; and a workpiece 303, wherein the workpiece 303 is a control instrument, and the workpiece 303 is fixedly connected to the front end of the fixed bracket 301 through screws.
Wherein, installation mechanism 4 includes: the mounting plate 401 is of a rectangular plate-shaped structure, and T-shaped protrusions are arranged on the left side and the right side of the front end of the mounting plate 401; two rectangular bulges are arranged below the mounting plate 401, and two rotating shafts are arranged above the mounting plate 401; a mounting member 402, the mounting member 402 is a circular box, the mounting member 402 is connected with the mounting plate 401 by a rotating shaft, and the mounting member 402 has a guide pipe mounted inside.
Wherein, coupling mechanism 5 is including: the connecting piece 501 is of a metal tubular structure, four rectangular grooves are formed in the outer side above the connecting piece 501, and a metal needle is arranged below the connecting piece 501; the fastener 502 is of a circular structure, and four rectangular protrusions are arranged inside the fastener 502; a circular through hole is formed below the fastener 502, and a metal needle of the connecting piece 501 is inserted into the circular through hole of the fastener 502; coupling mechanism 5 connects the separation kidney, inserts the income liquid mouth and the liquid outlet that enter the kidney respectively through the metal needle with connecting piece 501 to through fastener 502 with connecting piece 501 and kidney quick fixation, make the device be connected with the separation kidney with this can be quick.
Wherein, circulation mechanism 6 includes: a first circulating part 601, wherein an infusion pump is arranged above the first circulating part 601, an infusion straw is arranged below the first circulating part 601, and the first circulating part 601 is inserted into the fixing ring 302; the liquid storage part 602 is of a circular structure, and the liquid storage part 602 is connected below the first circulating part 601 through threads; under the control of the working unit 303, the first circulation unit 601 inputs the perfusion fluid inside the fluid storage unit 602 into the kidney via the infusion pump.
Wherein, collect mechanism 7 including: a liquid suction pump is arranged above the second circulating part 701, a round pipe is arranged below the second circulating part 701, a rectangular through hole is formed in the left side of the second circulating part 701, and the second circulating part 701 is inserted into the fixing ring 302; the pressure switch 702 is of a circular plate-shaped structure, and a spring is arranged below the pressure switch 702; the pressure switch 702 is installed inside the circular pipe of the second circulating member 701, and the pressure switch 702 is sealed with the circular pipe of the second circulating member 701; the collecting cylinder 703 is of a circular tubular structure, a rectangular through hole is formed in the right side of the collecting cylinder 703, and the rectangular through hole of the collecting cylinder 703 is communicated with the rectangular through hole of the second circulating piece 701; when the perfusion fluid enters the circular tube below the second circulating part 701, when the weight of the perfusion fluid reaches a certain degree, the pressure switch 702 is pressed to move downwards, so that the first circulating part 601 performs the next transfusion action under the feedback of the workpiece 303, and meanwhile the perfusion fluid in the circular tube of the second circulating part 701 enters the collecting cylinder 703 through the rectangular through hole.
When in use: a one-way valve 104 and an air release valve 105 are arranged in a through hole below the sealing cylinder 103, a columnar bulge below the contact 201 is sealed with the inside of the sealing cylinder 103 when in use, the contact 201 is lifted through a rack of the connecting plate 203 by rotating the rotating member 102 when in use, meanwhile, air enters the sealing cylinder 103 through the one-way valve 104 under the driving of the columnar projection of the contact element 201, and further, the contact member 201 can be supported by the air inside the sealing cylinder 103, and simultaneously, buffering is performed, thereby preventing the mechanism at the rise from being damaged to cause a sudden drop, damage is caused to the kidney in vitro inside the contact 201, and when the contact 201 needs to be put down, the release valve 105 can be opened, and the rotating member 102 is rotated to lower the contact member 201, during pouring, overflowing pouring liquid is collected through the contact element 201, flows into the through hole of the contact element 201 along the inclined surface, and is collected through the collection box 202; when the isolated kidney needs to be perfused, the isolated kidney is connected through the connecting mechanism 5, the metal needles of the connecting piece 501 are respectively inserted into a liquid inlet and a liquid outlet of the kidney, and the connecting piece 501 and the kidney are quickly fixed through the fastening piece 502, so that the device can be quickly connected with the isolated kidney, the trouble caused by suture and stitch removal is avoided, meanwhile, under the control of the workpiece 303, the perfusate in the liquid storage piece 602 is input into the kidney through the infusion pump by the first circulating piece 601, meanwhile, the perfusate in the kidney is sucked out by the second circulating piece 701 through the liquid suction pump of the second circulating piece 701, when the perfusate enters into the circular pipe below the second circulating piece 701, when the weight of the perfusate reaches a certain degree, the pressure switch 702 is pressed to move downwards, under the feedback of the workpiece 303, the first circulating piece 601 is used for next transfusion action, simultaneously inside the perfusate of the circular intraduct of second circulation piece 701 can enter into the collecting vessel 703 through the rectangle through-hole, through above mechanism, can control the perfusion cycle to the separation kidney effectively, prevent that the inside perfusate of kidney from too much causing the influence to the kidney, or the perfusate makes less perfusion effect unobvious, has also avoided the staff to need the trouble of observing the organ constantly simultaneously.
The embodiments of the present invention have been presented for purposes of illustration and description, and are not intended to be exhaustive or limited to the invention in the form disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiment was chosen and described in order to best explain the principles of the invention and the practical application, and to enable others of ordinary skill in the art to understand the invention for various embodiments with various modifications as are suited to the particular use contemplated.
Claims (10)
1. An ex vivo kidney perfusion apparatus for kidney transplantation, comprising:
a support mechanism (1);
a contact mechanism (2) is arranged above the supporting mechanism (1), and a columnar bulge below the contact piece (201) is inserted into the sealing cylinder (103); the front end of the supporting mechanism (1) is provided with a fixing mechanism (3), and the fixing bracket (301) is fixedly connected with the supporting box body (101) through a screw; an installation mechanism (4) is installed above the contact mechanism (2), and the T-shaped bulge of the installation plate (401) is inserted into the T-shaped groove of the fixing support (301); the rear end of the mounting mechanism (4) is provided with a connecting mechanism (5), and the connecting piece (501) is connected with a conduit inside the mounting piece (402); the front end of the fixing mechanism (3) is provided with a circulating mechanism (6) and a collecting mechanism (7), and the first circulating piece (601) and the second circulating piece (701) are inserted into the fixing ring (302).
2. The ex vivo kidney perfusion apparatus for kidney transplantation as defined in claim 1, wherein the support mechanism (1) comprises:
the supporting box body (101), the supporting box body (101) is of a rectangular structure, and a round-corner rectangular groove is formed in the rear end of the supporting box body (101); a circular through hole is formed in the right side of the supporting box body (101), and a rectangular bulge is formed in the front end of the supporting box body (101);
the rotating piece (102), the rotating piece (102) is of a circular structure, and a columnar bulge is arranged on the left side of the rotating piece (102); a gear is arranged on the left side of the columnar bulge of the rotating piece (102), and the columnar bulge of the rotating piece (102) is inserted into the through hole of the supporting box body (101);
the sealing device comprises a sealing cylinder (103), wherein the sealing cylinder (103) is a circular sleeve, the sealing cylinder (103) is fixedly connected inside the supporting box body (101), and two circular through holes are formed in the bottom of the sealing cylinder (103).
3. The ex vivo kidney perfusion apparatus for kidney transplantation as defined in claim 2, wherein said support mechanism (1) further comprises:
the check valve (104), the check valve (104) is inserted in the through hole of the bottom of the sealing cylinder (103);
the air release valve (105), the air release valve (105) inserts in the through-hole inside sealed section of thick bamboo (103), and the inside of air release valve (105) is installed sealed lid.
4. An ex vivo kidney perfusion device for kidney transplantation according to claim 1, wherein said contact means (2) comprises:
the contact element (201), the contact element (201) is a rectangular box body, the lower surface of the inside of the contact element (201) is a five-degree inclined plane, and the left side of the inside of the contact element (201) is provided with a through hole; a columnar bulge is arranged below the contact element (201), and a sealing ring is arranged below the columnar bulge of the contact element (201);
the collecting box (202), the collecting box (202) is a rectangular box body, and a fifteen-degree inclined plane is arranged below the collecting box (202); the collecting box (202) is fixedly connected below the contact element (201), the collecting box (202) is communicated with the contact element (201) through a through hole, and a liquid outlet is formed in the rear end of the collecting box (202);
the connecting plate (203), the connecting plate (203) is L-shaped plate structure, and the connecting plate (203) is fixedly connected below the contact element (201) through screws; the rear end of the connecting plate (203) is provided with a rack, and the rack of the connecting plate (203) is meshed with a gear of the rotating piece (102) of the supporting mechanism (1).
5. The ex vivo kidney perfusion apparatus for kidney transplantation as set forth in claim 1, wherein the fixing mechanism (3) comprises:
the fixing support (301), the fixing support (301) is a rectangular frame body, and the left side and the right side of the rear end of the fixing support (301) are provided with T-shaped grooves;
the fixing rings (302) are of L-shaped plate structures, circular through holes are formed in the fixing rings (302), and the two fixing rings (302) are fixedly connected to the front ends of the fixing supports (301) through screws;
the working piece (303), the working piece (303) is the control instrument, and the working piece (303) passes through screw fixed connection at the fixed bolster (301) front end.
6. The ex vivo kidney perfusion apparatus for kidney transplantation as claimed in claim 1, wherein said mounting means (4) comprises:
the mounting plate (401), the mounting plate (401) is a rectangular plate-shaped structure, and the left side and the right side of the front end of the mounting plate (401) are provided with T-shaped bulges; two rectangular bulges are arranged below the mounting plate (401), and two rotating shafts are arranged above the mounting plate (401);
the mounting piece (402) is a circular box body, the mounting piece (402) is connected with the mounting plate (401) through a rotating shaft, and the mounting piece (402) is internally provided with a guide pipe.
7. The ex vivo kidney perfusion apparatus for kidney transplantation as set forth in claim 1, wherein the connection mechanism (5) comprises:
the connecting piece (501) is of a metal tubular structure, four rectangular grooves are formed in the outer side above the connecting piece (501), and a metal needle is arranged below the connecting piece (501);
the fastening piece (502), the fastening piece (502) is a round structure, and four rectangular bulges are arranged inside the fastening piece (502); a circular through hole is formed below the fastening piece (502), and a metal needle of the connecting piece (501) is inserted into the circular through hole of the fastening piece (502).
8. An ex vivo kidney perfusion device for kidney transplantation according to claim 1, wherein said circulation means (6) comprises:
the infusion pump is arranged above the first circulating piece (601), an infusion straw is arranged below the first circulating piece (601), and the first circulating piece (601) is inserted into the fixing ring (302);
the liquid storage part (602), the liquid storage part (602) is circular structure, and the liquid storage part (602) passes through threaded connection in the below of first circulation piece (601).
9. The ex vivo kidney perfusion apparatus for kidney transplantation as claimed in claim 1, wherein said collection means (7) comprises:
a liquid suction pump is arranged above the second circulating piece (701), a round pipe is arranged below the second circulating piece (701), a rectangular through hole is formed in the left side of the second circulating piece (701), and the second circulating piece (701) is inserted into the fixing ring (302);
the pressure switch (702), the pressure switch (702) is a round plate-shaped structure, and a spring is arranged below the pressure switch (702); the pressure switch (702) is installed inside the circular pipe of the second circulating member (701), and the pressure switch (702) is sealed with the circular pipe of the second circulating member (701).
10. The ex vivo kidney perfusion apparatus for kidney transplantation as defined in claim 9, wherein said collection means (7) further comprises:
the collecting cylinder (703) is of a circular tubular structure, a rectangular through hole is formed in the right side of the collecting cylinder (703), and the rectangular through hole of the collecting cylinder (703) is communicated with the rectangular through hole of the second circulating piece (701).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110816912.6A CN113519503A (en) | 2021-07-20 | 2021-07-20 | Isolated kidney perfusion apparatus for kidney transplantation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110816912.6A CN113519503A (en) | 2021-07-20 | 2021-07-20 | Isolated kidney perfusion apparatus for kidney transplantation |
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| Publication Number | Publication Date |
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| CN113519503A true CN113519503A (en) | 2021-10-22 |
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| CN202110816912.6A Pending CN113519503A (en) | 2021-07-20 | 2021-07-20 | Isolated kidney perfusion apparatus for kidney transplantation |
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| CN (1) | CN113519503A (en) |
Citations (6)
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| US20110076666A1 (en) * | 2009-09-25 | 2011-03-31 | John Brassil | Organ Preservation System |
| CN205494073U (en) * | 2016-03-01 | 2016-08-24 | 铜仁学院 | Device for infusing and fixing lungs of experimental animals |
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| CN110859178A (en) * | 2019-12-23 | 2020-03-06 | 张嘉 | MRI (magnetic resonance imaging) -compatible in-vitro kidney perfusion system |
| CN111356364A (en) * | 2017-11-20 | 2020-06-30 | 体沃索股份有限公司 | Apparatus for perfusing an isolated organ |
| CN113016778A (en) * | 2021-02-08 | 2021-06-25 | 广东乾晖生物科技有限公司 | Isolated organ perfusion preservation system based on mesenchymal stem cells |
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- 2021-07-20 CN CN202110816912.6A patent/CN113519503A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20110076666A1 (en) * | 2009-09-25 | 2011-03-31 | John Brassil | Organ Preservation System |
| CN205494073U (en) * | 2016-03-01 | 2016-08-24 | 铜仁学院 | Device for infusing and fixing lungs of experimental animals |
| CN206115320U (en) * | 2016-10-26 | 2017-04-19 | 武汉大学 | Continuous perfusion system of isolated organ |
| CN111356364A (en) * | 2017-11-20 | 2020-06-30 | 体沃索股份有限公司 | Apparatus for perfusing an isolated organ |
| CN110859178A (en) * | 2019-12-23 | 2020-03-06 | 张嘉 | MRI (magnetic resonance imaging) -compatible in-vitro kidney perfusion system |
| CN113016778A (en) * | 2021-02-08 | 2021-06-25 | 广东乾晖生物科技有限公司 | Isolated organ perfusion preservation system based on mesenchymal stem cells |
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Application publication date: 20211022 |