CN113476205A - Eyeball vitreous cavity injection device capable of achieving accurate positioning and quantitative injection - Google Patents

Eyeball vitreous cavity injection device capable of achieving accurate positioning and quantitative injection Download PDF

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Publication number
CN113476205A
CN113476205A CN202110936734.0A CN202110936734A CN113476205A CN 113476205 A CN113476205 A CN 113476205A CN 202110936734 A CN202110936734 A CN 202110936734A CN 113476205 A CN113476205 A CN 113476205A
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China
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injection
syringe
eyeball
vitreous cavity
needle
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Granted
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CN202110936734.0A
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Chinese (zh)
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CN113476205B (en
Inventor
颜繁诚
王艳玲
王康
董宁
孟照洋
汪晓磊
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Beijing Friendship Hospital
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Beijing Friendship Hospital
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Priority to CN202311548079.7A priority patent/CN117481905A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/00736Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F2009/0035Devices for immobilising a patient's head with respect to the instrument
    • A61F2009/0043Devices for immobilising a patient's head with respect to the instrument by supporting the instrument on the patient's head, e.g. head bands
    • A61F2009/0052Devices for immobilising a patient's head with respect to the instrument by supporting the instrument on the patient's head, e.g. head bands the instrument being supported on the patient's eye

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention is suitable for the technical field of ophthalmic medical instruments, and discloses an injection device for injecting medicine into an eyeball vitreous cavity, which is used for accurate positioning and quantitative injection, wherein the inner side wall of a bracket is attached to the corneal edge of an eyeball of a patient, and then two positioning holes with certain distance are needle insertion inlets on the bracket, so that an injector can be positioned quickly, the depth and the angle of a needle head section of the injector entering the eyeball vitreous cavity are fixed due to the thickness and the gradient of the positioning holes of the bracket, the condition that the lens enters the eyeball with different depths and the needle insertion angle are not deviated when the needle head is inserted is avoided, the crystalline lens or peripheral retina is damaged when the needle head is inserted, and the medicine outlet holes on the needle head are arranged on the side surface of the periphery of the needle head section, so that the possibility that the traditional needle head injects the medicine to the fundus retina when injecting the medicine, especially the hidden danger of injecting to the macular part of the retina is avoided, and the arrangement of the bracket can also press and stop bleeding when the injector is extracted, the operation efficiency of the operation type is improved.

Description

Eyeball vitreous cavity injection device capable of achieving accurate positioning and quantitative injection
Technical Field
The invention belongs to the technical field of ophthalmic medical instruments, and particularly relates to an injection device for injecting medicine into an eyeball vitreous cavity, which is used for accurate positioning and quantitative injection.
Background
Intravitreal drug injection, injection of anti-VEGF drugs for wet AMD, diabetic retinopathy and other ocular fundus vascular diseases; hormone preparations such as triamcinolone acetonide injection and dexamethasone injection are injected. Methotrexate is injected to treat lymphoma; the Marantan and the topotecan are injected to treat retinoblastoma; injecting amphotericin B, fluconazole and voriconazole to treat fungal endophthalmitis; ganciclovir, tolerous (foscarnet) for treating viral retinitis. At present, the national ophthalmic industry has no unified and authoritative quality control standard, and particularly, the key problems related to the injection process and quality (such as injection equipment, injection technology and the like) are not uniformly recognized. The increasing frequency of potential risks of treating retinopathy using intravitreal drug injections highlights the importance and urgency of quality control.
The treatment method comprises the following steps:
1. the peribulbar anesthesia is performed conventionally, and if necessary, retrobulbar block anesthesia is performed.
2. The eyelids are opened with an eyelid retractor and the conjunctival sac is rinsed with diluted gentamicin solution or diluted organic iodine solution.
3. The prepared drug to be injected is extracted by using a 1m1 syringe, connecting a needle.
4. Fixing eyeball with toothed forceps 3.5-4 mm, 6-12 points (right eye) or 12-6 points (left eye) behind corneal limbus, penetrating eyeball with the injection needle 4-6 mm deep, with the needle pointing to center of vitreous cavity, and slowly injecting medicinal liquid. The needle tip direction should avoid subtending the retina, especially the posterior pole macula. After the liquid medicine is injected, the needle head is quickly pulled out, and the needle eye is immediately pressed by a cotton swab for 1 min.
5. Gentamicin 2 uquor and dexamethasone 2.5mg are injected under the conjunctiva.
The existing intravitreal injection method: when injecting the eyeball, need the patient cooperation, look to one side, keep the eyeball motionless, and then utilize the gauge to measure the position of pricking needle on the eyeball and in sclera surface nick location, because patient's eyeball turns to behind one side, often can't keep the eyeball fixed for a long time, and still need to fall the hand-held needle after the location measurement and find the needle insertion position of preceding with gauge score mark on the sclera again, lead to often need repeated many times to measure position and angle that just can confirm the pricking needle, inefficiency, the length of syringe needle for the injection is different simultaneously, lead to the depth of needle insertion unable the same, above these all probably increase the risk of operation.
Disclosure of Invention
The invention provides an injection device for injecting medicine into an eyeball vitreous cavity, which is used for accurate positioning and quantitative injection and aims to solve the problems of low efficiency and potential risk in the actual operation process of the existing vitreous cavity medicine injection method.
The invention is realized in such a way that the injection device for the eyeball vitreous cavity injection with accurate positioning and quantitative injection comprises
A syringe for quantitatively drawing a liquid medicine and injecting the liquid medicine into an eyeball of a patient;
the bracket is used for positioning the position of the injector, limiting the angle of the injector when the injector is inserted, supporting the injector and pressing the sclera part of the injector after the needle head is pulled out.
Preferably, the injector comprises a syringe and a piston rod inserted in the syringe in a pulling manner, wherein a sliding foot is arranged on the inner wall of the opening end of the syringe and slides in a notch on the outer wall of the piston rod, so that the piston rod is quantitatively limited.
Preferably, the notch comprises two limiting grooves which are formed in the symmetrical positions of the outer wall of the piston rod and are axially arranged along the piston rod, and one ends of the two limiting grooves are communicated through a semi-arc groove.
Preferably, the top of the piston rod is provided with two large and small arrow marks which are respectively corresponding to the two 0.05ml and 0.03ml limiting grooves one by one, and the open end of the needle cylinder is provided with another arrow mark corresponding to the sliding foot.
Preferably, the support sets up to crescent, and wholly for circular-arc laminating in eyeball surface, the both ends department of support respectively is provided with an ascending handle.
Preferably, the crescent inner side of the support corresponds to the corneal limbus of the eyeball, and two inclined positioning holes for inserting the injector are formed in the positions, 3.5mm and 4.0mm away from the corneal limbus, of the outer side of the support.
Preferably, the lower surface of the bracket is rough, and bumps for compression hemostasis of the taken-out part of the syringe are arranged near the two positioning holes.
Preferably, the support is provided with a thickness of 1mm to 1.5mm for defining the length of the needle of the syringe.
Preferably, the syringe has a closed needle tip with an aperture in a side wall and a length sufficient to penetrate tissue.
Compared with the prior art, the invention has the beneficial effects that: according to the injection device for injecting the medicine into the vitreous cavity of the eyeball with the accurate positioning and quantitative injection, the inner side wall of the support is attached to the corneal limbus of the eyeball of a patient, and the other two positioning holes with the determined distance on the support are needle insertion inlets, so that the injector can be positioned quickly.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic view of the structure of the syringe of the present invention;
FIG. 3 is a schematic view of the structure of the stent of the present invention;
FIG. 4 is a schematic cross-sectional view of the syringe of the present invention;
FIG. 5 is a schematic view of the position of the stent on the eyeball in the present invention;
FIG. 6 is a schematic cross-sectional view taken along line D-D in FIG. 5;
in the figure: 1. an injector; 11. a needle cylinder; 12. a piston rod; 13. a sliding foot; 14. a limiting groove; 15. a half-arc groove; 16. an arrow mark; 2. a support; 21. positioning holes; 22. a handle; 23. a bump;
A. a cornea; B. a limbus; C. the sclera.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Referring to fig. 1-6, the present invention provides a technical solution: an injection device for injecting medicine into the vitreous cavity of eyeball with accurate positioning and quantitative injection comprises
The injector 1 is used for quantitatively extracting the liquid medicine and injecting the liquid medicine into the eyeball of the patient;
and the bracket 2 is used for positioning the position of the injector 1, limiting the angle of the injector 1 when being inserted, supporting the injector 1 and pressing the part of the injector 1 after being taken out.
The invention can be attached to the corneal limbus of the eyeball of a patient through the inner side wall of the bracket 2, and then the other two positioning holes 21 with determined distance on the bracket 2 are the needle inserting inlets, thereby positioning the injector 1 more quickly, because the thickness of the bracket 2 makes the depth and the angle of the needle head section of the injector 1 entering the vitreous cavity of the eyeball fixed, the different depth and the inclination of the needle inserting angle of the needle head entering the eyeball when injecting the liquid medicine can not occur, thereby causing the occurrence of the situations of damaging crystalline lens or peripheral retina and the like when the needle head is inserted, simultaneously avoiding the possibility that the traditional needle head sprays to the fundus retina when injecting liquid medicine, especially the hidden trouble of spraying to the macula part of the retina, meanwhile, the arrangement of the bracket 2 can also press the needle insertion point when the injector 1 is pulled out to stop bleeding, so that the operation speed and efficiency of the operation type are improved.
Further, the method comprises the following steps of; the liquid outlet of the needle head of the injector 1 is arranged on the side surface and is used for avoiding the damage to the retina caused by directly spraying the liquid medicine to the retina when the liquid medicine is injected.
Because on patient's eyeball need be put into to support 2 to need carry out high temperature and high pressure disinfection to support 2 and handle, and then just need support 2 to be high temperature and high pressure resistant material, when support 2 covers on the eyeball, can not shelter from the syringe needle simultaneously, cause the not clear in operation field of vision, thereby need set up support 2 to transparent, and then whole support 2 need adopt materials such as high temperature and high pressure resistant transparent glass, plastics or colloid.
Syringe 1 includes syringe 11 and piston rod 12 of taking out the plug in syringe 11, and 11 open end inner walls of syringe are provided with runner 13, and this runner 13 slides in the notch of piston rod 12 outer wall for carry out the ration spacing to piston rod 12, and two along 12 axial spacing grooves 14 are seted up to the notch including the symmetrical position of piston rod 12 outer wall, and the one end of two spacing grooves 14 is linked together with crossing half arc groove 15.
Generally; the piston rod 12 is pushed towards the inside of the syringe 11 until the front end of the piston rod 12 abuts against the inner end of the syringe 11, then the piston rod 12 is rotated, so that the sliding foot 13 positioned in the half-arc groove 15 moves along the half-arc groove 15, the sliding foot moves from the upper end of one limiting groove 14 to the upper end of the other limiting groove 14, then the piston rod 12 is pulled outwards to extract the liquid medicine, and the sliding foot 13 on the needle tube slides along the limiting groove 14 until the sliding foot slides to the bottom of the limiting groove 14, so that the piston rod 12 cannot be pulled upwards, and the quantitative extraction of the liquid medicine is realized.
Two arrow marks 16 with one big and one small are arranged at the top of the piston rod 12 and respectively correspond to the two limit grooves 14 of 0.05ml and 0.03ml one by one, and the open end of the needle cylinder 11 is provided with another arrow mark 16 corresponding to the sliding foot 13.
Specifically, the method comprises the following steps of; big arrow mark 16 on the piston rod 12 corresponds the spacing groove 14 position of 0.05ml, the sign of 0.03ml that little arrow mark 16 corresponds, arrow mark 16 on the cylinder 11 corresponds the position of smooth foot 13, thereby through rotating piston rod 12, make the spout rotate and rotate in half arc groove 15 when both ends, align arrow mark 16 on the syringe needle with big arrow mark 16 or little arrow mark 16 on the piston rod 12 respectively, thereby the surface spout enters into the spacing groove 14 upper end that this arrow mark 16 corresponds, thereby can follow this spacing groove 14 and carry out the pull that corresponds the scale, be used for the ration extraction liquid medicine, make things convenient for doctor's use, avoid rough estimation to lead to the data discrepancy great, influence the problem of treatment.
Furthermore; the bracket 2 is crescent-shaped, is integrally in an arc shape and is attached to the surface of the eyeball, and two upward handles 22 are respectively arranged at two ends of the bracket 2; the crescent inner side of the support 2 corresponds to the corneal limbus of the eyeball, and two inclined positioning holes 21 for inserting the injector 1 are arranged at the positions 3.5mm and 4.0mm away from the corneal limbus on the outer side of the support 2.
It should be explained that: the whole of the support 2 is arc-shaped, and is attached to the surface of an eyeball, so that the mutual curvature is guaranteed to be close to each other, the accuracy of the position during needle insertion is guaranteed, and the compression hemostasis is performed on the needle hole left after the syringe 1 is taken out conveniently.
The positioning hole 21 is inclined, and the inclination angle is perpendicular to the eyeball surface and is deviated to the direction far away from the cornea, so that the distance of the needle entering the eyeball is shorter, and the liquid medicine is prevented from being shot onto the retina to influence a patient.
In addition; the support 2 is arranged in a crescent shape, so that the inner side arc of the support 2 is conveniently attached to the outer side of the corneal limbus, and then a doctor directly determines the position of the needle insertion according to the positions of the two positioning holes 21 on the support, thereby avoiding the problems that the position of the needle insertion needs to be determined for the sclera indentation through a ruler and the determination mode is low in efficiency.
Both ends of crescent respectively set up an ascending handle 22, and the person of facilitating the use gets to put and adjust support 2, and this handle 22's height is 5mm, and the diameter is 2 mm.
The vitreous cavity of the eyeball is injected, and in order to ensure the safety of the needle head penetrating into the vitreous cavity, the needle is generally inserted vertically at the position 3.5mm or 4.0mm away from the corneal limbus to ensure that the liquid medicine can be normally injected into the interior of the eyeball.
It is to be noted that; the lower surface of the bracket 2 is rough, and bumps 23 for pressing the parts of the syringe 1 after being taken out are arranged near the two positioning holes 21.
The lower surface of support 2 sets up to be coarse to support 2 is difficult to slide on the eyeball surface, can be comparatively firm and stable laminating in patient's eyeball, guarantees the stability of supporting syringe 1, is located near locating hole 21 and sets up a plurality of lugs 23 for after syringe 1 takes out, carries out the oppression after the deviation to the bleeding point in the eyeball, avoids the bleeding point to bleed continuously.
The holder 2 is provided with a thickness of 1mm to 1.5mm for a certain limit of the length of the needle of the syringe 1.
It is to be noted that; in order to ensure the consistency of medicine injection and needle insertion at each time and reduce the potential risk of damage to retina and crystalline lens during operation, the bracket 2 needs to be arranged with a certain thickness, and the positioning hole is designed in an inclined manner, so that the length and the needle insertion angle of the needle head which can finally enter the eyeball are limited, the needle head is ensured to be inserted into the vitreous cavity of the eyeball to smoothly inject medicine liquid, and the purpose of treatment is realized.
The working principle and the using process of the invention are as follows: after the device is installed, firstly, a doctor rotates the piston rod 12 in the needle cylinder 11 to the corresponding limiting groove 14 by confirming how much liquid medicine needs to be injected, then pushes the piston rod 12 to go deep into the needle cylinder 11, and then pulls out the piston rod 12 to extract the liquid medicine;
let the patient look to a certain direction, and keep the eye position unchangeable, then place the crescent inboard of support 2 along the corneal limbus, later select corresponding locating hole 21, insert syringe 1 along the inclined injection hole in the eyeball vitreous body intracavity, and inject liquid medicine into patient's eyeball vitreous body, later outwards extract syringe 1, move support 2 afterwards, let lug 23 under support 2 carry out the hemostasis by compression to the hemorrhage point after syringe 1 breaks away from.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.

Claims (9)

1. The utility model provides an eyeball vitreous cavity injection device of accurate location and ration injection which characterized in that: comprises that
The injector (1) is used for quantitatively extracting the liquid medicine and injecting the liquid medicine into the eyeball of the patient;
the support (2), the support (2) are used for right the position of syringe (1) is fixed a position, right angle when syringe (1) inserts is spacing, right syringe (1) supports and to syringe (1) annotate the position of pulling out the syringe needle after the medicine and oppress.
2. An injection device for vitreous cavity medicine injection with precise positioning and quantitative injection as claimed in claim 1, wherein: the injector (1) comprises a needle cylinder (11) and a piston rod (12) inserted in the needle cylinder (11) in a pulling mode, wherein a sliding foot (13) is arranged on the inner wall of the opening end of the needle cylinder (11), and the sliding foot (13) slides in a notch in the outer wall of the piston rod (12) and is used for quantifying and limiting the piston rod (12).
3. An injection device for vitreous cavity medicine injection with precise positioning and quantitative injection as claimed in claim 2, wherein: the notch comprises two limiting grooves (14) which are arranged at symmetrical positions of the outer wall of the piston rod (12) along the axial direction of the piston rod (12), and one ends of the two limiting grooves (14) are communicated through a semi-arc groove (15).
4. An injection device for vitreous cavity medicine injection with precise positioning and quantitative injection as claimed in claim 3, wherein: the top of the piston rod (12) is provided with two large and small arrow marks (16) which are respectively in one-to-one correspondence with the two limiting grooves (14) of 0.05ml and 0.03ml, and the open end of the needle cylinder (11) is provided with another arrow mark (16) corresponding to the sliding foot (13).
5. An injection device for vitreous cavity medicine injection with precise positioning and quantitative injection as claimed in claim 1, wherein: support (2) set up to crescent, and wholly laminate in the eyeball surface for circular-arc, the both ends department of support (2) respectively is provided with an ascending handle (22).
6. An injection device for vitreous cavity medicine injection with precise positioning and quantitative injection as claimed in claim 1, wherein: crescent inboard of support (2) is corresponding with the limbus of eyeball, the outside perpendicular distance crescent inside wall 3.5mm and 4.0 mm's of support (2) two all offer inclination be used for syringe (1) male locating hole (21).
7. An injection device for vitreous cavity medicine injection with precise positioning and quantitative injection as claimed in claim 6, wherein: the lower surface of the bracket (2) is rough, and bumps (23) used for pressing the taken-out part of the syringe (1) are arranged near the two positioning holes (21).
8. An injection device for vitreous cavity medicine injection with precise positioning and quantitative injection as claimed in claim 1, wherein: the thickness that support (2) set up is 1mm to 1.5mm for carry out certain restriction to the syringe needle length of syringe (1).
9. An injection device for vitreous cavity medicine injection with precise positioning and quantitative injection as claimed in claim 1, wherein: the needle top end of the syringe (1) is closed, the side surface of the syringe is provided with a hole, and the length of the syringe is enough to penetrate into tissues.
CN202110936734.0A 2021-08-16 2021-08-16 Injection device for injecting medicine into vitreous cavity of eyeball with accurate positioning and quantitative injection Active CN113476205B (en)

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Application Number Priority Date Filing Date Title
CN202110936734.0A CN113476205B (en) 2021-08-16 2021-08-16 Injection device for injecting medicine into vitreous cavity of eyeball with accurate positioning and quantitative injection
CN202311548079.7A CN117481905A (en) 2021-08-16 2021-08-16 Eyeball accurate positioning support

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Application Number Priority Date Filing Date Title
CN202110936734.0A CN113476205B (en) 2021-08-16 2021-08-16 Injection device for injecting medicine into vitreous cavity of eyeball with accurate positioning and quantitative injection

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113952109A (en) * 2021-10-21 2022-01-21 成都米戈思医疗技术有限公司 Eyeball is fixed and supplementary piercing depth
CN114983673A (en) * 2022-07-20 2022-09-02 北京安龙生物医药有限公司 Injection device for ophthalmic injection and application thereof

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Publication number Priority date Publication date Assignee Title
US20030060763A1 (en) * 2000-01-06 2003-03-27 Penfold Philip Leslie Guide means for intraocular injection
CN102895731A (en) * 2012-09-12 2013-01-30 广州军区广州总医院 Injection device for vitreous chamber
CN208808830U (en) * 2018-04-16 2019-05-03 温州医科大学 A kind of ocular implantation material injection device
CN209137617U (en) * 2018-10-17 2019-07-23 上海交通大学医学院附属第九人民医院 A kind of accurate syringe of pen-holding type piston
CN211658492U (en) * 2019-11-25 2020-10-13 王芬 Syringe for injecting medicine into vitreous cavity
CN213552855U (en) * 2020-10-19 2021-06-29 四川大学华西医院 Vitreous body injection positioner and vitreous body injection assembly

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030060763A1 (en) * 2000-01-06 2003-03-27 Penfold Philip Leslie Guide means for intraocular injection
CN102895731A (en) * 2012-09-12 2013-01-30 广州军区广州总医院 Injection device for vitreous chamber
CN208808830U (en) * 2018-04-16 2019-05-03 温州医科大学 A kind of ocular implantation material injection device
CN209137617U (en) * 2018-10-17 2019-07-23 上海交通大学医学院附属第九人民医院 A kind of accurate syringe of pen-holding type piston
CN211658492U (en) * 2019-11-25 2020-10-13 王芬 Syringe for injecting medicine into vitreous cavity
CN213552855U (en) * 2020-10-19 2021-06-29 四川大学华西医院 Vitreous body injection positioner and vitreous body injection assembly

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113952109A (en) * 2021-10-21 2022-01-21 成都米戈思医疗技术有限公司 Eyeball is fixed and supplementary piercing depth
CN113952109B (en) * 2021-10-21 2024-03-22 成都米戈思医疗技术有限公司 Eyeball fixing and auxiliary puncturing device
CN114983673A (en) * 2022-07-20 2022-09-02 北京安龙生物医药有限公司 Injection device for ophthalmic injection and application thereof
CN115887101A (en) * 2022-07-20 2023-04-04 北京安龙生物医药有限公司 Injection device for ophthalmic injection and application thereof

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