CN113462103A - Medical antibacterial light-resistant and emigration-resistant PVC composite material and preparation method thereof - Google Patents
Medical antibacterial light-resistant and emigration-resistant PVC composite material and preparation method thereof Download PDFInfo
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- CN113462103A CN113462103A CN202110985987.7A CN202110985987A CN113462103A CN 113462103 A CN113462103 A CN 113462103A CN 202110985987 A CN202110985987 A CN 202110985987A CN 113462103 A CN113462103 A CN 113462103A
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L27/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
- C08L27/02—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L27/04—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
- C08L27/06—Homopolymers or copolymers of vinyl chloride
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/03—Polymer mixtures characterised by other features containing three or more polymers in a blend
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Abstract
The invention relates to a medical antibacterial light-resistant and migration-resistant PVC composite material and a preparation method thereof, solves the technical problems that the existing PVC composite material is easy to migrate and does not have an antibacterial effect, and provides a medical antibacterial light-resistant and migration-resistant PVC composite material with good light-resistant performance, antibacterial performance and migration-resistant performance. The material comprises the following components in parts by weight: 100 parts of polyvinyl chloride; 30-70 parts of a plasticizer PPA; 25-45 parts of a bio-based antibacterial polyester plasticizer QBPE; 30-50 parts of bio-Based Polyester (BPE); 1-2 parts of calcium-zinc stabilizer. The invention also provides a preparation method thereof. The invention can be used in the field of medical antibacterial light-resistant materials.
Description
Technical Field
The invention relates to a high polymer material and a preparation method thereof, in particular to a medical antibacterial light-resistant and emigration-resistant PVC composite material and a preparation method thereof.
Background
PVC has lower cost advantage and excellent performance, is widely used in the field of medical health, and is a disposable medical consumable with larger annual consumption. At present, infusion apparatus products without a light-shielding function are generally used clinically; but because of some injection drugs such as nitroprusside, nitroglycerin and vitamin B2And the like, the drugs are unstable in chemical property, deteriorate and discolor when being exposed to light, even have photosensitive reaction, phototoxicity and the like, and the photochemical reaction reduces the due value of the drugs and even can generate side effects. Therefore, in order to ensure the safety and reliability of the treatment, the light shielding is required to be added in the infusion process so as to meet the treatment effect and the requirement.
The light-shielding medical polyvinyl chloride equipment is usually prepared by adding a light-shielding agent or dye into polyvinyl chloride plastic to meet the light-shielding requirement of the medical equipment, wherein the added light-shielding agent or dye can be dissolved into liquid medicine to a certain extent, and the transmittance of the medical plastic is mostly over 30 percent, so that the light-shielding purpose cannot be achieved, the effect of the infused medicine is seriously influenced, and the harm to a certain degree can be possibly brought to patients. Meanwhile, the existing materials cannot play an antibacterial role, and pathogenic microorganisms such as bacteria, mold and the like in the environment are ubiquitous, so that the health of human beings is threatened all the time.
Disclosure of Invention
The invention aims to solve the technical problems that the existing PVC composite material is easy to migrate and does not have an antibacterial effect, and provides a medical antibacterial light-resistant and migration-resistant PVC composite material with good light-resistant performance, antibacterial performance and migration-resistant performance and a preparation method thereof.
Therefore, the invention provides a medical antibacterial light-resistant and emigration-resistant PVC composite material which comprises the following components in parts by weight: 100 parts of polyvinyl chloride; 30-70 parts of a plasticizer PPA; 25-45 parts of a bio-based antibacterial polyester plasticizer QBPE; 30-50 parts of bio-Based Polyester (BPE); 1-2 parts of calcium-zinc stabilizer.
Preferably, the molecular weight of the QBPE is between 1000 and 2000.
Preferably, the molecular weight of the bio-based polyester BPE is 20000.
The invention also provides a preparation method of the medical antibacterial light-resistant and migration-resistant PVC composite material, which comprises the following steps: (1) mixing polyvinyl chloride powder, a plasticizer PPA, a bio-based antibacterial polyester plasticizer QBPPE and a stabilizer in proportion, adding the mixture into a high-speed mixer, heating and stirring the mixture at a low speed of 20-40 rmp to 80 ℃, adding the bio-based polyester BPE, operating at 400-600 rmp, discharging the mixture to a cold mixer when the temperature reaches 160 ℃, and cooling the mixture to 40-50 ℃; the weight ratio of parts of each component is as follows: 100 parts of polyvinyl chloride; 30-70 parts of a plasticizer PPA; 25-45 parts of a bio-based antibacterial polyester plasticizer QBPE; 30-50 parts of bio-Based Polyester (BPE); 1-2 parts of a calcium-zinc stabilizer; (2) granulating the material obtained in the step (1) by using a double-screw extruder, wherein the rotating speed of a screw of a host is 40-100 rmp, and the temperature of each section of the extruder is as follows: the temperature of the first section is 100-120 ℃, the temperature of the second section is 120-150 ℃, the temperature of the third section is 150-170 ℃, the temperature of the fourth section is 150-170 ℃, the temperature of the die head is 145-165 ℃, and the materials are plasticized by an extruder, granulated by air cooling and granulated
The invention has the following beneficial effects:
the bio-based antibacterial polyester plasticizer QBPPE not only plays a plasticizing role, but also plays an excellent light-shielding effect, and simultaneously the quaternary ammonium salt component in the plasticizer QBPPE effectively improves the antibacterial performance of the PVC material; the added bio-based polyester BPE is a macromolecular polymer, can effectively inhibit the migration of plasticizers PPA, QBPPE and the like, and can avoid the influence of the migration of a light shielding agent on the drugs to a certain extent.
Detailed Description
The present invention will be further described with reference to the following examples.
Example 1
The mixture ratio (parts by weight) is as follows: 100 parts of polyvinyl chloride; 30 parts of a plasticizer PPA; 30 parts of a bio-based antibacterial polyester plasticizer QBPE; 45 parts of bio-based polyester BPE; 2 parts of a calcium zinc stabilizer;
the bio-based antibacterial polyester plasticizer QBPPE is prepared from bio-based polyester BPE, N dimethyl hexamethylene diamine and brominated alkane; the molecular weight is between 1000-2000. The molecular weight of the bio-based polyester BPE is 20000.
A preparation method of a medical antibacterial light-resistant and migration-resistant PVC composite material comprises the following steps: (1) mixing polyvinyl chloride powder, a plasticizer PPA, a bio-based antibacterial polyester plasticizer QBPPE and a stabilizer in proportion, adding the mixture into a high-speed mixer, heating and stirring the mixture at a low speed of 20rmp to 80 ℃, adding the bio-based polyester BPE, operating at 450rmp, discharging the mixture to a cold mixer when the temperature reaches 160 ℃, and cooling the mixture to 40 ℃; (2) granulating the material obtained in the step (1) by using a double-screw extruder, wherein the rotating speed of a screw of a host is 50rmp, and the temperature of each section of the extruder is as follows: the temperature of the first section is 120 ℃, the temperature of the second section is 150 ℃, the temperature of the third section is 150 ℃, the temperature of the fourth section is 170 ℃, the temperature of the die head is 165 ℃, and the materials are plasticized, air-cooled and granulated by an extruder.
Example 2
The mixture ratio (parts by weight) is as follows: 100 parts of polyvinyl chloride; 40 parts of a plasticizer PPA; 30 parts of a bio-based antibacterial polyester plasticizer QBPE; 45 parts of bio-based polyester BPE; 1.5 parts of calcium zinc stabilizer.
The bio-based antibacterial polyester plasticizer QBPPE is prepared from bio-based polyester BPE, N dimethyl hexamethylene diamine and brominated alkane; the molecular weight is between 1000-2000.
The molecular weight of the bio-based polyester BPE is 20000.
A preparation method of a medical antibacterial light-resistant and migration-resistant PVC composite material comprises the following steps: (1) mixing polyvinyl chloride powder, a plasticizer PPA, a bio-based antibacterial polyester plasticizer QBPPE and a stabilizer in proportion, adding the mixture into a high-speed mixer, heating and stirring the mixture at a low speed of 20rmp to 80 ℃, adding the bio-based polyester BPE, operating at 450rmp, discharging the mixture to a cold mixer when the temperature reaches 160 ℃, and cooling the mixture to 40 ℃; (2) granulating the material obtained in the step (1) by using a double-screw extruder, wherein the rotating speed of a screw of a host is 50rmp, and the temperature of each section of the extruder is as follows: the temperature of the first section is 120 ℃, the temperature of the second section is 150 ℃, the temperature of the third section is 150 ℃, the temperature of the fourth section is 170 ℃, the temperature of the die head is 165 ℃, and the materials are plasticized, air-cooled and granulated by an extruder.
Example 3
The mixture ratio (parts by weight) is as follows: 100 parts of polyvinyl chloride; 50 parts of a plasticizer PPA; 35 parts of a bio-based antibacterial polyester plasticizer QBPE; 45 parts of bio-based polyester BPE; 1.5 parts of calcium zinc stabilizer.
The bio-based antibacterial polyester plasticizer QBPPE is prepared from bio-based polyester BPE, N dimethyl hexamethylene diamine and brominated alkane; the molecular weight is between 1000-2000.
The molecular weight of the bio-based polyester BPE is 20000.
A preparation method of a medical antibacterial light-resistant and migration-resistant PVC composite material comprises the following steps: (1) mixing polyvinyl chloride powder, a plasticizer PPA, a bio-based antibacterial polyester plasticizer QBPPE and a stabilizer in proportion, adding the mixture into a high-speed mixer, heating and stirring the mixture at a low speed of 20rmp to 80 ℃, adding the bio-based polyester BPE, operating at 450rmp, discharging the mixture to a cold mixer when the temperature reaches 160 ℃, and cooling the mixture to 40 ℃; (2) granulating the material obtained in the step (1) by using a double-screw extruder, wherein the rotating speed of a screw of a host is 50rmp, and the temperature of each section of the extruder is as follows: the temperature of the first section is 120 ℃, the temperature of the second section is 150 ℃, the temperature of the third section is 150 ℃, the temperature of the fourth section is 170 ℃, the temperature of the die head is 165 ℃, and the materials are plasticized, air-cooled and granulated by an extruder.
Example 4
The mixture ratio (parts by weight) is as follows: 100 parts of polyvinyl chloride; 60 parts of a plasticizer PPA; 41 parts of a bio-based antibacterial polyester plasticizer QBPE; 48 parts of bio-based polyester BPE; 1.1 parts of calcium zinc stabilizer.
The bio-based antibacterial polyester plasticizer QBPPE is prepared from bio-based polyester BPE, N dimethyl hexamethylene diamine and brominated alkane; the molecular weight is between 1000-2000.
The molecular weight of the bio-based polyester BPE is 20000.
A preparation method of a medical antibacterial light-resistant and migration-resistant PVC composite material comprises the following steps: (1) mixing polyvinyl chloride powder, a plasticizer PPA, a bio-based antibacterial polyester plasticizer QBPPE and a stabilizer in proportion, adding the mixture into a high-speed mixer, heating and stirring the mixture at a low speed of 20rmp to 80 ℃, adding the bio-based polyester BPE, operating at 450rmp, discharging the mixture to a cold mixer when the temperature reaches 160 ℃, and cooling the mixture to 40 ℃; (2) granulating the material obtained in the step (1) by using a double-screw extruder, wherein the rotating speed of a screw of a host is 50rmp, and the temperature of each section of the extruder is as follows: the temperature of the first section is 120 ℃, the temperature of the second section is 150 ℃, the temperature of the third section is 150 ℃, the temperature of the fourth section is 170 ℃, the temperature of the die head is 165 ℃, and the materials are plasticized, air-cooled and granulated by an extruder.
Example 5
The mixture ratio (parts by weight) is as follows: 100 parts of polyvinyl chloride; 70 parts of a plasticizer PPA; 40 parts of a bio-based antibacterial polyester plasticizer QBPE; 50 parts of bio-based polyester BPE; 1 part of calcium zinc stabilizer.
The bio-based antibacterial polyester plasticizer QBPPE is prepared from bio-based polyester BPE, N dimethyl hexamethylene diamine and brominated alkane; the molecular weight is between 1000-2000.
The molecular weight of the bio-based polyester BPE is 20000.
A preparation method of a medical antibacterial light-resistant and migration-resistant PVC composite material comprises the following steps: (1) mixing polyvinyl chloride powder, a plasticizer PPA, a bio-based antibacterial polyester plasticizer QBPPE and a stabilizer in proportion, adding the mixture into a high-speed mixer, heating and stirring the mixture at a low speed of 20rmp to 80 ℃, adding the bio-based polyester BPE, operating at 450rmp, discharging the mixture to a cold mixer when the temperature reaches 160 ℃, and cooling the mixture to 40 ℃; (2) granulating the material obtained in the step (1) by using a double-screw extruder, wherein the rotating speed of a screw of a host is 50rmp, and the temperature of each section of the extruder is as follows: the temperature of the first section is 120 ℃, the temperature of the second section is 150 ℃, the temperature of the third section is 150 ℃, the temperature of the fourth section is 170 ℃, the temperature of the die head is 165 ℃, and the materials are plasticized, air-cooled and granulated by an extruder.
Table 1: performance indices for examples 1-5:
note: the tensile strength is detected by using the test standard GB/T1004-2006.
The detection method of the breaking elongation adopts the test standard of GB/T1004-2006.
The detection method of the Shore hardness adopts the test standard GB/T531-2008.
The light transmittance detection method adopts the test standard GB/T2410-2008.
The method for detecting the bacteriostasis rate adopts the test standard of GB/T31402-2015.
The detection method of the migration resistance rate comprises the following steps: weighing a batch of sample strips, respectively placing the sample strips in three solvents of 200mL of water, ethanol and petroleum ether, soaking for 48h at 25 ℃, taking out the sample strips, placing the sample strips in a blast oven at 30 ℃ for drying for 48h, weighing the weight of the sample strips, and calculating the mass loss rate.
However, the above description is only exemplary of the present invention, and the scope of the present invention should not be limited thereby, and the replacement of the equivalent components or the equivalent changes and modifications made according to the protection scope of the present invention should be covered by the claims of the present invention.
Claims (4)
1. The medical antibacterial light-resistant and emigration-resistant PVC composite material is characterized by comprising the following components in parts by weight: 100 parts of polyvinyl chloride; 30-70 parts of a plasticizer PPA; 25-45 parts of a bio-based antibacterial polyester plasticizer QBPE; 30-50 parts of bio-Based Polyester (BPE); 1-2 parts of calcium-zinc stabilizer.
2. The medical antibacterial light-resistant and migration-resistant PVC composite material according to claim 1, wherein the molecular weight of the bio-based polyester plasticizer QBPE is 1000-2000.
3. The medical antibacterial light-resistant and migration-resistant PVC composite material according to claim 1, wherein the molecular weight of the bio-based polyester BPE is 20000.
4. The preparation method of the medical antibacterial light-resistant and migration-resistant PVC composite material as claimed in any one of claims 1 to 3, which is characterized by comprising the following steps:
(1) mixing polyvinyl chloride powder, a plasticizer PPA, a bio-based antibacterial polyester plasticizer QBPPE and a stabilizer in proportion, adding the mixture into a high-speed mixer, heating and stirring the mixture at a low speed of 20-40 rmp to 80 ℃, adding the bio-based polyester BPE, operating at 400-600 rmp, discharging the mixture to a cold mixer when the temperature reaches 160 ℃, and cooling the mixture to 40-50 ℃;
the weight ratio of parts of each component is as follows: 100 parts of polyvinyl chloride; 30-70 parts of a plasticizer PPA; 25-45 parts of a bio-based antibacterial polyester plasticizer QBPE; 30-50 parts of bio-Based Polyester (BPE); 1-2 parts of a calcium-zinc stabilizer;
(2) granulating the material obtained in the step (1) by using a double-screw extruder, wherein the rotating speed of a screw of a host is 40-100 rmp, and the temperature of each section of the extruder is as follows: the temperature of the first section is 100-120 ℃, the temperature of the second section is 120-150 ℃, the temperature of the third section is 150-170 ℃, the temperature of the fourth section is 150-170 ℃, the temperature of the die head is 145-165 ℃, and the materials are plasticized by an extruder, air-cooled and granulated.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202110985987.7A CN113462103A (en) | 2021-08-26 | 2021-08-26 | Medical antibacterial light-resistant and emigration-resistant PVC composite material and preparation method thereof |
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| CN202110985987.7A CN113462103A (en) | 2021-08-26 | 2021-08-26 | Medical antibacterial light-resistant and emigration-resistant PVC composite material and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116253960A (en) * | 2022-12-26 | 2023-06-13 | 常州天龙医用新材料有限公司 | Migration-resistant antibacterial PVC material and preparation method thereof |
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| CN103571105A (en) * | 2013-11-06 | 2014-02-12 | 江南大学 | Environment-friendly polyvinyl chloride resin composition and preparation method thereof |
| CN105237907A (en) * | 2015-10-12 | 2016-01-13 | 上海新上化高分子材料有限公司 | Antibacterial shading medical polyvinyl chloride plastic and preparation method thereof |
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2021
- 2021-08-26 CN CN202110985987.7A patent/CN113462103A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103571105A (en) * | 2013-11-06 | 2014-02-12 | 江南大学 | Environment-friendly polyvinyl chloride resin composition and preparation method thereof |
| CN105237907A (en) * | 2015-10-12 | 2016-01-13 | 上海新上化高分子材料有限公司 | Antibacterial shading medical polyvinyl chloride plastic and preparation method thereof |
Non-Patent Citations (2)
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| YAO XIE,ET AL.,: "Antibacterial plasticizers based on bio-based engineering elastomers for medical PVC: synthesis, characterization and properties", 《POLYMER CHEMISTRY》 * |
| 唐颂超: "《高分子材料成型加工 第三版》", 31 May 2013 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116253960A (en) * | 2022-12-26 | 2023-06-13 | 常州天龙医用新材料有限公司 | Migration-resistant antibacterial PVC material and preparation method thereof |
| CN116253960B (en) * | 2022-12-26 | 2024-05-28 | 常州天龙医用新材料有限公司 | Migration-resistant antibacterial PVC material and preparation method thereof |
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