CN113456174A

CN113456174A - Tissue transplantation reducing mechanism

Info

Publication number: CN113456174A
Application number: CN202110549201.7A
Authority: CN
Inventors: 程若川; 王军; 张兵; 周兴龙; 龚蕾
Original assignee: Saide Biotechnology Shandong Co ltd
Current assignee: Saide Biotechnology Shandong Co ltd
Priority date: 2021-05-19
Filing date: 2021-05-19
Publication date: 2021-10-01
Anticipated expiration: 2041-05-19
Also published as: CN113456174B

Abstract

The invention provides a tissue transplantation smashing device, and belongs to the technical field of medical instrument manufacturing; the invention comprises the following steps: the device comprises an accommodating pipe, a push rod, a stirring rod and a base; one end of the accommodating tube is an injection port, and the other end of the accommodating tube is an opening; the push rod is inserted into the accommodating pipe from the opening direction and can slide along the inner wall of the accommodating pipe; the stirring rod is sleeved in the push rod and can rotate in the push rod; one end of the stirring rod is provided with a crushing knife which is positioned in the accommodating pipe; a coupler is arranged at the other end of the stirring rod and is positioned at the bottom of the push rod; the base is provided with a rotating shaft capable of driving the coupler, and the rotating shaft can be inserted into the coupler; the base is further provided with a fixer, and the accommodating pipe is detachably mounted on the base through the fixer. The transplantation crushing device can conveniently crush and inject tissues to be transplanted, and the accommodating tube and the base are designed in a separated mode, so that the transplantation crushing device is convenient to use integrally, lower in cost and easy to popularize.

Description

Tissue transplantation reducing mechanism

Technical Field

The invention relates to the manufacturing technology of medical instruments, in particular to a tissue transplantation smashing device, and belongs to the technical field of tissue transplantation equipment production.

Background

Need transplant gland tissue in partial operation, common transplant gland tissue divide into around transplant, forearm injection transplantation, all need smash the tissue in these two kinds of circumstances and transplant, need use the scalpel to cut up under the circumstances that does not have this equipment, it is extremely inconvenient and gland tissue crushing size is different in the operation, use this equipment to smash through control rotational speed tool bit, make gland tissue smash evenly and improve the survival rate

Adult parathyroid gland is in the shape of brownish-yellow flat ellipse, and has a total weight of about 120mg, a length of about 3-8 mm, a width of 2-5 mm, and a thickness of 0.5-2 mm. Parathyroid hormone is a peptide hormone, and has the main functions of influencing the metabolism of calcium and phosphorus in vivo, acting on bone cells and osteoclasts, mobilizing calcium from bones, dissolving bone salts, increasing the concentration of calcium ions in blood, and simultaneously acting on intestines and renal tubules to increase the absorption of calcium, thereby increasing the blood calcium. The body maintains the stability of blood calcium under the co-regulation of parathyroid hormone and calcitonin. If the secretion function of the parathyroid gland is low, the blood calcium concentration is reduced, and tetany disease appears; if the function is hyperfunction, bone resorption will occur, and fracture will easily occur. Parathyroid gland dysfunction can cause an aberration in the ratio of calcium to phosphorus in the blood. Therefore, the determination of parathyroid hormone has important clinical value for early prediction of the occurrence of hypocalcemia after thyroidectomy.

Taking parathyroid gland transplantation as an example, in the previous experiment or detection step, a tissue homogenizer is often needed to crush tissues, and parathyroid glands are small and are difficult to be crushed by measuring bottom by using the tissue homogenizer, so the method in the prior art is to manually shear the parathyroid glands with the size of mung beans by scissors, the process is long in time consumption, in addition, the parathyroid glands are implanted into experimental recipients by using an injector after being sheared, and if the parathyroid glands cannot be sufficiently crushed, the injection step cannot be carried out.

Therefore, it is an object of the present invention to provide a tissue crushing device that can be easily operated and can rapidly crush and transplant tissue.

Disclosure of Invention

The invention provides a novel tissue transplantation smashing device, which is characterized in that a smashing knife is arranged in a containing pipe, and a base separation type design is adopted, so that the technical problems that the smashing is not easy to happen and the operation is inconvenient in the tissue transplantation process in the prior art are solved.

The tissue transplantation crushing device of the embodiment of the invention comprises: the device comprises an accommodating pipe, a push rod, a stirring rod and a base;

one end of the accommodating tube is an injection port, and the other end of the accommodating tube is an opening; the push rod is inserted into the accommodating pipe from the opening direction and can slide along the inner wall of the accommodating pipe; the stirring rod is sleeved in the push rod and can rotate in the push rod;

one end of the stirring rod is provided with a crushing knife which is positioned in the accommodating pipe; a coupler is arranged at the other end of the stirring rod and is positioned at the bottom of the push rod;

the base is provided with a rotating shaft capable of driving the coupler, and the rotating shaft can be inserted into the coupler; the base is further provided with a fixer, and the accommodating pipe is detachably mounted on the base through the fixer.

The tissue graft size reduction apparatus as described above, wherein the holder comprises: a fixed mount and a support arm; the fixed frame is fixed on the top of the base through the supporting arm; the fixing frame is a plastic card or a spring clamp with a C-shaped opening.

The tissue transplantation smashing device comprises a base, a motor, a driving device and a control device, wherein the base is internally provided with the motor which is provided with an output shaft; the rotating shaft is sleeved on the output shaft, and the rotating shaft is located at the top of the base.

The tissue transplantation crushing device as described above, wherein the front end of the push rod is provided with a piston for sealing; the side wall of the piston is provided with a plurality of sealing rings which are contacted with the inner wall of the accommodating pipe.

The tissue transplantation smashing device is characterized in that the front end of the push rod is provided with an annular clamping groove, and the piston is installed on the push rod through the annular clamping groove.

The tissue transplantation smashing device comprises a stirring rod, a plurality of sealing grooves and a plurality of sealing grooves, wherein the stirring rod is provided with a plurality of annular sealing grooves; the stirring rod penetrates through the piston and is in contact with the piston through the annular sealing groove.

The tissue transplantation crushing device is characterized in that the crushing knife is a multi-blade saw-tooth crushing knife and comprises a plurality of blades distributed on different planes;

the crushing cutter is provided with a shaft sleeve, and the crushing cutter is sleeved at the top end of the stirring rod through the shaft sleeve.

The tissue transplantation smashing device comprises a base, wherein the top of the base is a panel, and a control switch is further arranged on the panel; the control switch is electrically connected with the motor.

The tissue transplantation reduction device as described above, wherein the fixing frame is mounted to a tip end of the support arm; the bottom of the supporting arm is the same as the top of the output shaft in horizontal height; the height of the supporting arm is equal to that of the stirring rod.

The tissue transplantation pulverization apparatus as described above, wherein an injection needle is provided on the injection port; the accommodating tube is provided with a dial gauge; the accommodating tube is a transparent tube.

The transplantation crushing device can conveniently crush and inject tissues to be transplanted, and the accommodating tube and the base are designed in a separated mode, so that the transplantation crushing device is convenient to use integrally, lower in cost and easy to popularize.

Drawings

FIG. 1 is a schematic view showing the overall structure of a tissue graft crushing apparatus according to an embodiment of the present invention;

FIG. 2 is a schematic view showing the overall assembly of the tissue graft reduction apparatus according to the embodiment of the present invention;

FIG. 3 is a schematic front view of a tissue transplant reducing apparatus according to an embodiment of the present invention;

FIG. 4 is a schematic cross-sectional view of a receiving tube of the tissue transplantation reduction device according to an embodiment of the present invention;

fig. 5 is a partially enlarged view of fig. 4.

Detailed Description

FIG. 1 is a schematic view showing the overall structure of a tissue graft crushing apparatus according to an embodiment of the present invention; and with reference to figures 2 to 5.

The tissue transplantation crushing device of the embodiment of the invention comprises: the device comprises an accommodating pipe 1, a push rod 2, a stirring rod 3 and a base 7; this example is mainly used for autologous cell homogenate transplantation and parathyroid gland transplantation.

One end of the accommodating tube 1 is an injection port, and the other end of the accommodating tube is an opening; in general, as shown in fig. 2, an injection needle 10 is provided at the injection port; a dial gauge is arranged on the accommodating pipe 1; the accommodating tube 10 is a transparent tube.

The push rod 2 is inserted into the accommodating tube 1 from the opening direction and can slide along the inner wall of the accommodating tube 1; the push rod 2 is inserted into the receiving tube 1 and slides, thereby pressing the liquid and tissue inside the receiving tube. The stirring rod 3 is sleeved in the push rod 2 and can rotate in the push rod 2; the rotation axis direction of the stirring rod 3 is consistent with the sliding length direction of the push rod 2.

One end of the stirring rod 3 is provided with a crushing knife 4, and the crushing knife 4 is positioned in the accommodating pipe 1; the crushing knife 4 can rotate along with the stirring rod 3, and cuts and crushes the tissues in the accommodating tube 1 through the high-speed cutting function.

A coupler 30 is arranged at the other end of the stirring rod 3, and the coupler 30 is positioned at the bottom of the push rod 2; that is, the crushing blades and the couplers are distributed at both ends of the push rod 2.

As shown in fig. 4, a rotating shaft 80 capable of driving the coupling 30 is disposed on the base 7, and the rotating shaft 80 can be inserted into the coupling 30; the base 7 is further provided with a fixer, and the accommodating tube 1 is detachably mounted on the base 7 through the fixer.

The fixer is used for fixing the top of the accommodating pipe 1, so that the accommodating pipe is firmly installed on the base, and then is in butt joint with the rotating shaft through the coupler, the rotating shaft rotates to drive the stirring rod and the crushing knife to rotate at a high speed, and tissues in the accommodating pipe are crushed.

The device of the embodiment has the following operation steps in the process of carrying out tissue transplantation:

1. cutting a tissue to be crushed, transferring the tissue into the accommodating tube, inserting the push rod, and discharging redundant air in the accommodating tube;

2. the physiological saline or other medicaments are sucked through the injection needle on the accommodating tube, and the tissue can be ensured to survive to the maximum extent by controlling the parameters of the related medicaments;

3. fixing the accommodating tube on the fixer, aligning a coupler on the accommodating tube with a rotating shaft on the base, starting the power device, and rotating the rotating shaft at a high speed so as to drive the stirring rod and the crushing knife to rotate at a high speed, thereby crushing tissues in the accommodating tube;

4. and after the crushing is finished, obtaining tissue fluid with the crushing degree reaching the standard, taking down the whole accommodating tube from the fixer, and finishing tissue transplantation or inoculation by adopting an injection needle.

In the tissue graft size reduction apparatus of the present embodiment, as shown in fig. 1, the holder includes: a fixed mount 6 and a support arm 5; the fixed frame 6 is fixed on the top of the base 7 through the supporting arm 5; the fixing frame 6 is a plastic card or a spring clip with a C-shaped opening. The fixing frame 6 can also be a sleeve structure, a magnetic attraction structure or other detachable structures.

In the tissue transplantation pulverizing apparatus of the present embodiment, as shown in fig. 2, a motor 8 is disposed in the base 7, and the motor 8 has an output shaft; the rotating shaft 80 is sleeved on the output shaft, and the rotating shaft 80 is positioned at the top of the base. The axes of the rotating shaft, the output shaft and the stirring rod are kept on the same straight line.

In the tissue transplantation comminuting device of the present embodiment, as shown in fig. 4 and 5, the front end of the push rod 2 is provided with a piston 20 for sealing; the side wall of the piston 20 has a plurality of sealing rings 200 contacting the inner wall of the receiving tube 1. The cross section of the sealing ring 200 is U-shaped, rectangular or semicircular, so that a multi-layer sealing effect can be formed between the piston and the accommodating pipe, and the sealing property is improved.

Further, in order to ensure that the piston and the push rod have good connection strength and sealing performance, the front end of the push rod 2 is provided with an annular clamping groove 21, and the piston 20 is mounted on the push rod 2 through the annular clamping groove 21. The annular clamping groove 21 is formed in the radial surface of the top of the push rod, so that a part of the piston is clamped into the annular clamping groove, and the piston and the push rod are prevented from falling off.

Referring to fig. 5, the tissue graft crushing apparatus of the present embodiment is provided with a plurality of annular sealing grooves 300 formed in the stirring bar 3; the pin 3 passes through the piston 20 and contacts the piston 20 through the annular seal groove 300.

Correspondingly, the top of the piston 20 is provided with a through hole to facilitate the stirring rod transmission; in the through hole, the piston 20 is in contact with the pin through a plurality of annular seal grooves 300, and liquid leakage and seepage along the pin are avoided.

In the tissue transplantation crushing device of the embodiment, the crushing knife 4 is a multi-blade saw-tooth crushing knife and comprises a plurality of blades distributed on different planes; a plurality of blades distributed on different planes can ensure that the rotating process has a cutting effect and can also generate the effects of crushing and shearing.

The crushing knife 4 is provided with a shaft sleeve 40, and the crushing knife 4 is sleeved at the top end of the stirring rod 3 through the shaft sleeve 40.

In the tissue transplantation smashing device of the embodiment, the top of the base 7 is a panel 71, and the panel 71 is further provided with a control switch 72; the control switch 72 is electrically connected to the motor 8 to control the start and stop of the motor.

In addition, in this embodiment, a storage battery 9 is further disposed in the base 7, and the storage battery 9 is electrically connected to the motor 8 through a control switch, and is used for providing electric energy for the motor. The battery 9 is typically a rechargeable lithium battery.

The specific control switch 72 includes: a touch key 91 and a touch switch 90, both of which are located below the panel 71.

Accordingly, in order to firmly fix the motor 8, the base 7 has a bottom plate 70, a motor groove 78 is formed on the bottom plate 70, and the motor 8 is fixed on the motor groove 78.

In the tissue transplantation pulverization apparatus of the present embodiment, the fixing frame 6 is mounted on the top end of the support arm 5; the bottom of the supporting arm 5 is at the same level as the top of the output shaft; the height of the supporting arm 5 is equal to that of the stirring rod 3, so that the containing pipe can be well fixed on the fixing frame 6 no matter how many tissues are crushed and how much liquid is sucked in the containing pipe 1.

The above-mentioned serial numbers of the embodiments of the present invention are merely for description and do not represent the merits of the embodiments. Through the above description of the embodiments, those skilled in the art will clearly understand that the above embodiment method can be implemented by some modifications plus the necessary general technical overlap; of course, the method can also be realized by simplifying some important technical features in the upper level. Based on such understanding, the technical solution of the present invention essentially or contributing to the prior art is: the overall composition and construction, and the method as described in the various embodiments of the present invention.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A tissue graft reduction device, comprising: the device comprises an accommodating pipe, a push rod, a stirring rod and a base;

2. The tissue graft morcellating device of claim 1, wherein the holder comprises: a fixed mount and a support arm; the fixed frame is fixed on the top of the base through the supporting arm; the fixing frame is a plastic card or a spring clamp with a C-shaped opening.

3. The tissue graft morcellating device of claim 2, wherein a motor is disposed within the base, the motor having an output shaft; the rotating shaft is sleeved on the output shaft, and the rotating shaft is located at the top of the base.

4. The tissue graft comminution device of one of claims 1 to 3, wherein a piston for sealing is provided at a front end of the push rod; the side wall of the piston is provided with a plurality of sealing rings which are contacted with the inner wall of the accommodating pipe.

5. The tissue graft comminution device of claim 4, wherein the forward end of the push rod is provided with an annular groove, and the piston is mounted on the push rod through the annular groove.

6. The tissue graft morcellating device of claim 4, wherein the agitator shaft is provided with a plurality of annular seal grooves; the stirring rod penetrates through the piston and is in contact with the piston through the annular sealing groove.

7. The tissue graft comminution device of one of claims 1 to 3, wherein the crushing blade is a multi-blade serrated crushing blade comprising a plurality of blades distributed in different planes;

8. The tissue graft comminution device of claim 3, wherein the top of the base is a faceplate having a control switch disposed thereon; the control switch is electrically connected with the motor.

9. The tissue graft morcellating device of claim 3, wherein the holder is mounted to a top end of the support arm; the bottom of the supporting arm is the same as the top of the output shaft in horizontal height; the height of the supporting arm is equal to that of the stirring rod.

10. The tissue graft morcellating device of claim 1, wherein the injection port is provided with an injection needle; the accommodating tube is provided with a dial gauge; the accommodating tube is a transparent tube.