CN113453713A - 用于治疗癌症的具有修饰的b5r基因的溶瘤痘苗病毒 - Google Patents
用于治疗癌症的具有修饰的b5r基因的溶瘤痘苗病毒 Download PDFInfo
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/70503—Immunoglobulin superfamily
- C07K14/70532—B7 molecules, e.g. CD80, CD86
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- A61K2039/525—Virus
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Applications Claiming Priority (3)
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| GBGB1816547.2A GB201816547D0 (en) | 2018-10-10 | 2018-10-10 | Oncolytic virus for the treatment of cancer |
| GB1816547.2 | 2018-10-10 | ||
| PCT/GB2019/052877 WO2020074902A1 (en) | 2018-10-10 | 2019-10-10 | Oncolytic vaccinia virus with modified b5r gene for the treatment of cancer |
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| CN113453713A true CN113453713A (zh) | 2021-09-28 |
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| CN201980081698.5A Pending CN113453713A (zh) | 2018-10-10 | 2019-10-10 | 用于治疗癌症的具有修饰的b5r基因的溶瘤痘苗病毒 |
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| JP (1) | JP7410139B2 (enExample) |
| KR (1) | KR20210102196A (enExample) |
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| GB (1) | GB201816547D0 (enExample) |
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| CA3262167A1 (en) * | 2022-07-27 | 2024-02-01 | Astrazeneca Ab | COMBINATIONS OF RECOMBINATING VIRUSES EXPRESSING INTERLEUKIN-12 WITH PD-1/PDL1 INHIBITORS |
| WO2025184411A1 (en) | 2024-02-27 | 2025-09-04 | Calidi Biotherapeutics (Nevada), Inc. | Serum-resistant eev viruses and uses thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170020938A1 (en) * | 2014-04-01 | 2017-01-26 | Queen Mary University Of London | Oncolytic Vaccinia Virus |
| US20170340687A1 (en) * | 2016-05-30 | 2017-11-30 | Astellas Pharma Inc. | Novel genetically engineered vaccinia viruses |
| WO2018049261A1 (en) * | 2016-09-09 | 2018-03-15 | Icellhealth Consulting Llc | Oncolytic virus expressing immune checkpoint modulators |
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2018
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2019
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- 2019-10-10 EP EP19794623.9A patent/EP3863669A1/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170020938A1 (en) * | 2014-04-01 | 2017-01-26 | Queen Mary University Of London | Oncolytic Vaccinia Virus |
| CN106795527A (zh) * | 2014-04-01 | 2017-05-31 | 玛丽女王伦敦大学 | 溶瘤病毒 |
| US20170340687A1 (en) * | 2016-05-30 | 2017-11-30 | Astellas Pharma Inc. | Novel genetically engineered vaccinia viruses |
| WO2018049261A1 (en) * | 2016-09-09 | 2018-03-15 | Icellhealth Consulting Llc | Oncolytic virus expressing immune checkpoint modulators |
Non-Patent Citations (1)
| Title |
|---|
| ELIZABETH MATHEW 等: "The extracellular domain of vaccinia virus protein B5R affects plague phenotype, extracellualr enveloped virus release, and intracellular actin tail formation", JOURNAL OF VIROLOGY, vol. 72, no. 3, pages 2430 * |
Also Published As
| Publication number | Publication date |
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| KR20210102196A (ko) | 2021-08-19 |
| JP2022502066A (ja) | 2022-01-11 |
| CA3123973A1 (en) | 2020-04-16 |
| JP7410139B2 (ja) | 2024-01-09 |
| US20210332384A1 (en) | 2021-10-28 |
| WO2020074902A1 (en) | 2020-04-16 |
| GB201816547D0 (en) | 2018-11-28 |
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