CN113440252B

CN113440252B - Laser catheter with adjustable light spot

Info

Publication number: CN113440252B
Application number: CN202110892057.7A
Authority: CN
Inventors: 钟晨; 陶茜; 吴寒; 李力
Original assignee: Guangdong Diguang Medical Technology Co ltd
Current assignee: Guangdong Diguang Medical Technology Co ltd
Priority date: 2021-08-04
Filing date: 2021-08-04
Publication date: 2023-03-31
Anticipated expiration: 2041-08-04
Also published as: CN113440252A

Abstract

The invention relates to a laser catheter with adjustable light spots. The device comprises a laser transmitter, a laser receiver and a laser processing unit, wherein the laser transmitter is used for generating multiple paths of laser pulses; the transmission fiber core is coupled with the laser transmitter and is used for transmitting the laser pulse emitted by the laser transmitter to output a laser spot; the transmission fiber core is provided with at least two transmission channels which are coaxially arranged, a refraction area is formed between every two adjacent transmission channels, and the refractive index of the refraction area is smaller than that of the transmission channels; a catheter body for receiving and conducting the laser spot. Different laser pulses are controlled to be turned on and turned off, so that the transmission fiber core emits laser spots in different shapes. So as to facilitate laser ablation of lesions of different shapes. In the process, different laser catheters do not need to be replaced, and the operation is convenient.

Description

Laser catheter with adjustable light spot

Technical Field

The invention relates to the technical field of laser catheters, in particular to a laser catheter with adjustable light spots.

Background

With the development of laser technology and medical technology, laser ablation technology is becoming an important means for treating cardiovascular diseases. In the laser ablation technology, a laser catheter is adopted to guide laser pulses to a lesion position in a blood vessel for irradiation, so that the effects of eliminating plaque tissues and dredging the blood vessel are achieved.

In the actual operation of the conventional laser catheter, since the shape of the lesion is irregular, in the laser ablation treatment process, the laser ablation is usually performed multiple times by using fiber optic catheters with various sizes to eliminate the lesion.

However, the above laser catheter is troublesome in operation because the optical fiber catheter needs to be replaced many times during operation. There is a need for a laser catheter that can ablate lesions of different shapes.

Disclosure of Invention

Therefore, the laser catheter with the adjustable light spot is provided for solving the problem that when the laser catheter carries out laser ablation on irregular focuses, different laser catheters need to be replaced, and operation is troublesome.

A laser catheter with adjustable beam spot, comprising:

a laser transmitter including a laser generator for generating a plurality of laser pulses;

the transmission fiber core is coupled with the laser transmitter and is used for transmitting the laser pulse emitted by the laser transmitter to output a laser spot; at least two transmission channels which are coaxially arranged are formed on the transmission fiber core, a refraction area is formed between the adjacent transmission channels, and the refractive index of the refraction area is smaller than that of the transmission channels;

a catheter body for receiving and conducting the laser spot.

In one embodiment, the width of the refraction region is less than or equal to 10um.

In one embodiment, the transmission fiber core includes a central fiber core and an annular fiber core, the annular fiber core is sleeved outside the central fiber core and is coaxially arranged to form the transmission channel, and the laser transmitter includes a laser module coupled to the central fiber core and the annular fiber core respectively.

In one embodiment, the transmission fiber core includes a central fiber core and a plurality of annular fiber cores, the annular fiber cores are sequentially coaxially sleeved along the radial direction of the central fiber core, and the laser transmitter includes laser modules respectively coupled with the central fiber core and the annular fiber cores so as to send laser pulses to the central fiber core and the annular fiber cores through the corresponding laser modules.

In one embodiment, the transmission channel has at least one perturbation portion for perturbing the laser light during transmission of the laser light, wherein the perturbation portion includes a spirally extending section, and/or the perturbation portion has a first bending section and a second bending section, and the first bending section and the second bending section are respectively bent towards different directions.

In one embodiment, the catheter body comprises an incident end face and an emergent end face, the incident end face is provided with more than two incident areas, the incident areas are connected with the corresponding transmission fiber cores to receive the corresponding laser spots, the emergent end face comprises emergent areas, and the number of the emergent areas is the same as that of the incident areas and corresponds to that of the incident areas one to one.

In one embodiment, the distance from the center of part of the exit area to the center of the exit end face is different from the distance from the center of the corresponding incident area to the center of the incident end face.

In one embodiment, the catheter body includes a fiber optic bundle coupled to the transmission core to receive the laser spot.

In one embodiment, the distance between the end face of the fiber bundle and the end face of the transmission core is less than 5um.

In one embodiment, the laser transmitter and the transmission core are coupled to each other by a focusing lens or by fiber fusion splicing.

According to the laser catheter with the adjustable light spots, the laser transmitter transmits laser pulses of different paths to the transmission fiber core, and the laser light spots formed by the transmission fiber core are received and transmitted through the catheter main body, so that laser ablation is performed on a focus. The refraction area can lead the laser in each transmission fiber core to be bound in the respective transmission fiber core for propagation, and ensures that the shape of the laser spot is convenient to control. Different laser pulses are controlled to be started and stopped, so that laser spots of different shapes are emitted by the transmission fiber core. So as to facilitate laser ablation of lesions of different shapes. In the process, different laser catheters do not need to be replaced, and the operation is convenient.

Drawings

Fig. 1 is a schematic diagram of a laser catheter apparatus according to an embodiment of the present invention.

FIG. 2 is a graph of the transmission core versus refractive index according to one embodiment of the present invention.

Fig. 3 is a schematic diagram of an output end face structure of a laser transmitter according to an embodiment of the present invention.

FIG. 4 is a schematic structural view of a twisted transmission core according to an embodiment of the present invention.

Fig. 5 is a schematic structural view of a catheter body according to an embodiment of the present invention.

Fig. 6 is a schematic structural diagram of an incident end surface according to an embodiment of the present invention.

Fig. 7 is a schematic structural diagram of an exit end face according to an embodiment of the present invention.

FIG. 8 is a schematic view of a fiber optic catheter outputting a laser beam according to one embodiment of the present invention.

FIG. 9 is a schematic diagram of a laser spot output by a transmission core in accordance with one embodiment of the present invention.

FIG. 10 is a schematic view of an ablation spot on the output end face of a fiber optic catheter in accordance with an embodiment of the present invention.

Reference numerals:

100. a laser transmitter; 101. a first laser module; 102. a second laser module; 103. a third laser module; 200. a transmission core; 201. A central core; 202. an annular core; 203. a first core; 204. a second core; 205. a disturbing section; 220. a refractive region; 300. a catheter body; 310. a fiber optic bundle; 311. an optical fiber; 320. an incident end face; 321. a first incident region; 322. a second incident region; 323. a third incident region; 330. an exit end face; 331. a first exit area; 332. a second emission region; 333. a third exit area; 340. a first opening; 350. a second opening; 360. a guidewire channel; 400. a laser beam;

a-f laser spots; g-l ablation spots.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein, as those skilled in the art will recognize without departing from the spirit and scope of the present invention.

In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and are not to be considered limiting of the invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or to implicitly indicate the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.

In the present invention, unless otherwise explicitly stated or limited, the terms "mounted," "connected," "fixed," and the like are to be construed broadly, e.g., as being permanently connected, detachably connected, or integral; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

In the present invention, unless otherwise expressly stated or limited, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. As used herein, the terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like are for purposes of illustration only and do not denote a single embodiment.

Referring to fig. 1, an embodiment of the invention provides a laser catheter with adjustable light spot, which includes a laser emitter 100, a transmission core 200, and a catheter main body 300.

In one embodiment, the laser transmitter 100 may generate different laser pulses. The wavelength of each laser pulse may be the same. For example, a laser pulse having a wavelength of 355mm may be selected.

In one embodiment, the transmission cores 200 form at least two transmission channels arranged coaxially. The transmission channel may transmit a corresponding laser pulse emitted by the laser transmitter 100 and output a laser spot.

Specifically, in some embodiments, as shown in fig. 1 and 2, the transmission core 200 may include a central core 201 and a ring core 202. The ring core 202 is disposed outside the central core 201, and the two are disposed coaxially to form the transmission channels. A refractive region 220 is provided between the central core 201 and the annular core 202. The refractive index at the refractive region 220 is smaller than that of the transmission core 200 so that the laser light is confined in the transmission channel in which the laser light is located during the transmission of the laser light in the transmission channel. The width of the aforementioned refraction region 220 refers to: the distance between the refractive region 220 and the surface of the central core 201, and the refractive region 220 and the inner surface of the annular core 202. In some embodiments, the width of the refractive region 220 is less than or equal to 10um.

In some embodiments, the transmission core 200 may be selected to be a multimode optical fiber 311, some of which areIn one embodiment, the numerical aperture of the multimode optical fiber 311

. Wherein n is _core Refractive indices of the central core 201 and the ring core 202, n _clad Is the refractive index of the refractive region 220. In one embodiment, the central core 201 and the ring core 202 may be made of pure silica glass, the refractive region 220 may be made of fluorine-doped glass, and the refractive index of the refractive region 220 may be adjusted by controlling the amount of fluorine doping to form the refractive index difference required for guiding light.

Correspondingly, as shown in fig. 1 and 3, the laser transmitter 100 includes laser modules coupled to the central core 201 and the ring core 202, respectively. Wherein the laser module coupled to the central core 201 may generate a first laser pulse and the laser module coupled to the ring core 202 may generate a second laser pulse, the first laser pulse and the second laser pulse having the same laser wavelength. Other parameters of the first laser pulse and the second laser pulse may be different, such as repetition frequency of the laser pulses may be different. The repetition frequency range can be arbitrarily selected in the range of 30-80 Hz. When the laser modules are coupled to the corresponding central core 201 or ring core 202, they may be coupled to each other by fusion splicing through a focusing lens or an optical fiber 311.

By controlling the corresponding laser module, the laser can be selectively excited, so that the corresponding transmission channel transmits the laser and outputs the corresponding light spot.

It should be noted here that the number of laser modules may be the same as or greater than the number of transmission channels. For example, in one embodiment, as shown in fig. 1, the number of laser modules is the same as the number of transmission channels, and corresponds to one another.

In another embodiment, as shown in fig. 3, the number of laser modules is greater than the number of transmission channels, and each transmission channel corresponds to at least one laser module. For example, for a ring core 202, it corresponds to more than two laser modules, and the laser modules are arranged along the ring direction of the ring core 202, and the arrangement mode can be uniformly arranged. The above arrangement has at least the following advantages: 1. when special requirements are placed on the energy distribution of the light spot or the power of a single laser module is limited, the power of the laser in a certain transmission channel can be improved by overlapping the laser modules. 2. The multiple laser modules help to improve the uniformity of the laser energy in the annular core 202.

In other embodiments, the transmission core 200 may include a central core 201 and a plurality of annular cores 202. The plurality of annular fiber cores 202 are sequentially and coaxially sleeved along the radial direction of the central fiber core 201. Similarly, the central core 201 has a refractive region 220 with an adjacent annular core 202, and the adjacent annular cores 202 also have refractive regions 220 with each other.

Correspondingly, the laser transmitter 100 includes laser modules coupled to the central core 201 and the plurality of annular cores 202, respectively, to emit different laser pulses to the central core 201 and the plurality of annular cores 202 through the respective laser modules. Likewise, the number of laser modules may be equal to or greater than the number of transmission channels, i.e., the number of laser modules is equal to or greater than the sum of the number of annular cores 202 and central cores 201.

Furthermore, in some embodiments, as shown in FIG. 1, the transmission cores 200 are straight. In other embodiments, as shown in FIG. 4, the transmission core 200 has at least one perturbation 205. Wherein the perturbation 205 comprises a helically extending segment. In addition, the disturbing portion 205 may also have a first bending section and a second bending section, and the first bending section and the second bending section are bent in different directions. The above-described manner corresponds to at least two bends of the transmission core 200, so that the transmission core 200 forms the perturbation 205, and the laser light can be totally reflected in the transmission core 200 when it is transmitted in the transmission core 200.

During the transmission of the laser light along the transmission core 200, the laser light propagates in a straight line. When the transmission core 200 has the perturbation 205, since the perturbation 205 is nonlinear, the laser light is deviated in the transmission core 200 during the laser light transmission. That is, the laser light may be totally reflected within the transmission core 200 several times during the transmission process, i.e., the laser light transmission is disturbed. After the laser is disturbed, laser spots formed on the output end face of the transmission fiber core 200 can be uniformly distributed on the end face of the transmission fiber core 200, so that the laser spots output by the transmission fiber core 200 are uniform, and the subsequent catheter main body 300 is convenient to transmit the laser spots, so that uniform ablation spots are obtained, and the lesion is ablated more uniformly.

For example, in some embodiments, as shown in FIG. 4, the transmission core 200 has a plurality of perturbations 205 arranged in sequence. The disturbance 205 of the transmission core 200 is a helically extending segment, and the disturbance 205 is twisted. For example, in obtaining the transmission core 200, the transmission core 200 may be wound around a cylindrical auxiliary member surface such that the transmission core 200 forms the spirally extending perturbation 205.

For another example, in some embodiments, the perturbation portion 205 has a first bending section and a second bending section, and the first bending section and the second bending section are respectively bent toward different directions, so that the perturbation portion 205 is formed like an S shape, or a plurality of S shapes can be continuously arranged.

In some embodiments, as shown in fig. 1 and 5, the catheter body 300 includes a fiber bundle 310, the fiber bundle 310 being capable of receiving the light spot output by the transmission core 200. The optical fiber bundle 310 may include a plurality of optical fibers 311, and the optical fibers 311 are arranged in a compact manner, for example, in a circular arrangement as shown in fig. 6. The above-described manner may be such that the maximum number of optical fibers 311 can be arranged per unit area of the optical fiber bundle 310 in the case where the diameter of the optical fibers 311 is constant. In addition, the diameter of the optical fiber 311 may be selected to be 70um. The catheter body 300 may be 0.9mm in diameter.

As shown in fig. 5-7, the catheter body 300 includes an entrance end face 320 and an exit end face 330. The incident end surface 320 refers to an end surface of the optical fiber bundle 310 connected to the transmission core 200, and a distance between the end surface of the optical fiber bundle 310 and the end surface of the transmission core 200 is less than or equal to 5um, so that the optical fiber bundle 310 and the transmission core 200 are coupled with less loss. The bundle 310 of optical fibers and the transmission core 200 may be secured by a connector of optical fibers 311. The exit end face 330 refers to the end face of the fiber bundle 310 that is distal from the transmission core 200. As shown in fig. 8, an ablation laser beam 400 is output from the exit end face 330 to form a corresponding ablation spot for laser ablation of the lesion.

The incident end surface 320 is provided with more than two incident regions, and the incident regions are connected with the corresponding transmission fiber cores 200 to receive the corresponding laser spots. The exit end surface 330 includes exit areas, and the number of the exit areas is the same as the number of the incident areas, and the exit areas correspond to the incident areas one by one.

As shown in fig. 6 and 7, the distance from the center of the partial exit area to the center of the exit end surface 330 is different from the distance from the center of the corresponding incident area to the center of the incident end surface 320. In some embodiments, the area of the exit end face 330 is larger than the area of the entrance end face 320. Further, in some embodiments, as shown in fig. 5, the catheter body 300 is provided with a guide wire channel 360, the end of the guide wire channel 360 having two openings, a first opening 340 and a second opening 350. Wherein the first opening 340 is located at a sidewall of the catheter body 300. The second opening 350 is located at the exit end face 330 of the catheter body 300. The guide wire channel 360 may be configured to facilitate movement of the laser catheter within the blood vessel under the guidance of a metal guide wire (not shown). The diameter of the guide wire channel 360 may be slightly larger than the diameter of the metal guide wire, for example, 0.37mm may be selected. In this embodiment, the area of the exit end surface 330 is larger than the area of the entrance end surface 320, for example, in an embodiment, the diameter of the entrance end surface 320 is 0.7mm, and the diameter of the exit end surface 330 may be 0.9mm. In addition, the distance from each exit area to the center of the exit end surface 330 is greater than the distance from the center of the corresponding entrance area to the center of the entrance end surface 320. In addition, the incident region is a circular incident region or an annular incident region, and the exit region is a circular exit region or an annular exit region, so as to arrange the optical fiber bundle 310.

In the laser ablation process, different laser modules can be controlled to be opened and closed according to different focuses to deliver corresponding laser pulses, so that corresponding laser spots are input to the catheter main body 300 and output as corresponding ablation spots through transmission of the optical fiber bundle 310 to irradiate the focuses.

For the sake of understanding, the following description will be made by taking the illustrated embodiment as an example.

As shown in fig. 1-3, in the illustrated embodiment, the transmission core 200 includes a central core 201 and two annular cores 202. For ease of description, the two annular core 202 profiles will be designated as a first core 203 and a second core 204. The first core 203 and the second core 204 are coaxially sleeved in sequence along the outward direction of the center of the central core 201. Refractive regions 220 are formed between adjacent cores.

Correspondingly, as shown in fig. 3, the laser transmitter 100 includes a first laser module 101 coupled to the central core 201, a second laser module 102 coupled to the first core 203, and a third laser module 103 coupled to the second core 204. The first laser module 101 is located in the middle of the emitting end of the laser emitter 100. The number of the second laser modules 102 is 6, and the second laser modules are annularly arranged around the outer edge of the first laser module 101. The number of the third laser modules 103 is 12 and is arranged around the outer edge of the annular module ring formed by the second laser modules 102.

When the first laser module 101, the second laser module 102 and the third laser module 103 are excited simultaneously, a laser spot a as shown in fig. 9 can be obtained correspondingly. When the third laser module 103 is excited, the laser spot b shown in fig. 9 can be obtained correspondingly. When the first laser module 101 and the third laser module 103 are excited, a laser spot c shown in fig. 9 can be obtained. When the first laser module 101 and the second laser module 102 are excited, a laser spot d shown in fig. 9 can be obtained. When the second laser module 102 is excited, a laser spot e as shown in fig. 9 can be obtained. When the first laser module 101 is excited, a laser spot f shown in fig. 9 can be obtained.

Correspondingly, the catheter body 300 includes an entrance end face 320 and an exit end face 330. As shown in fig. 6, the incident end surface 320 includes three incident regions, namely a first incident region 321, a second incident region 322, and a third incident region 323. As shown in fig. 7, the exit end surface 330 includes three exit regions, i.e., a first exit region 331, a second exit region 332, and a third exit region 333. Since the catheter body 300 is provided with the guide wire channel 360, the exit end face 330 is the exit end face 330 having the second opening 350.

In the illustrated embodiment, the optical fiber 311 having an end surface located in the first entrance region 321 is coupled to the central core 201, and the other end surface is located in the first exit region 331. The optical fiber 311 having an end surface located in the second incident region 322 is coupled to the first core 203, and the other end surface is located in the second exit region 332. The optical fiber 311 having an end surface positioned in the third incident region 323 is coupled to the second core 204, and the other end surface is positioned in the third exit region 333.

When the third laser module 103 is excited, the exit end surface 330 can output an ablation spot g as shown in fig. 10. When the second laser module 102 is excited, the exit end surface 330 can output an ablation spot h as shown in fig. 10. When the first laser module 101 is excited, the exit end surface 330 can output an ablation spot i as shown in fig. 10. When the first laser module 101, the second laser module 102 and the third laser module 103 are excited simultaneously, the corresponding exit end surface 330 can output an ablation spot j as shown in fig. 10. When the first laser module 101 and the second laser module 102 are excited, the exit end surface 330 can output an ablation spot k as shown in fig. 10. When the first laser module 101 and the third laser module 103 are excited, the corresponding exit end surface 330 can output an ablation spot l as shown in fig. 10.

In the illustrated embodiment, the on-off of the different laser modules can be controlled to realize that the obtained ablation spots form a required shape to meet different shapes of focuses. In addition, in the process, the laser guide pipes with different sizes do not need to be replaced, and the operation is convenient.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent should be subject to the appended claims.

Claims

1. A laser catheter with adjustable light spot, comprising:

the catheter main body comprises an optical fiber bundle, the optical fiber bundle is used for receiving and conducting the laser light spots and outputting ablation light spots, and the ablation light spots are used for irradiating focuses;

the transmission fiber core comprises a central fiber core and an annular fiber core, the annular fiber core is sleeved outside the central fiber core and coaxially arranged to form the transmission channels respectively, and the laser transmitter comprises a laser module which is coupled with the central fiber core and the annular fiber core respectively; each transmission channel is correspondingly coupled with at least one laser module; and one annular fiber core corresponds to more than two laser modules, and each laser module is arranged along the annular direction of the corresponding annular fiber core.

2. The adjustable-spot laser catheter according to claim 1, wherein the width of the refraction area is less than or equal to 10um.

3. The laser catheter with the adjustable light spot according to claim 1, wherein the transmission fiber core includes a central fiber core and a plurality of ring fiber cores, the plurality of ring fiber cores are sequentially coaxially sleeved along a radial direction of the central fiber core, and the laser transmitter includes laser modules respectively coupled to the central fiber core and the plurality of ring fiber cores, so as to transmit laser pulses to the central fiber core and the plurality of ring fiber cores through the corresponding laser modules.

4. The laser catheter with the adjustable light spot according to claim 1, wherein the transmission channel has at least one disturbing part for disturbing the laser light during the laser light transmission, wherein the disturbing part comprises a spiral extending section, and/or the disturbing part has a first bending section and a second bending section, and the first bending section and the second bending section are respectively bent towards different directions.

5. The laser catheter with the adjustable light spot according to claim 1, wherein the catheter body includes an incident end face and an emergent end face, the incident end face is provided with two or more incident areas, the incident areas are connected with the corresponding transmission fiber cores to receive the corresponding laser light spots, the emergent end face includes emergent areas, and the number of the emergent areas is the same as that of the incident areas, and the emergent areas are in one-to-one correspondence.

6. The laser catheter with adjustable light spot according to claim 5, wherein the distance from the center of part of the exit area to the center of the exit end surface is different from the distance from the center of the corresponding incident area to the center of the incident end surface.

7. The laser catheter with the adjustable light spot as claimed in claim 5, wherein the catheter body has a guide wire channel, the guide wire channel has two openings, one opening is located on a side wall of the catheter body, and the other opening is located on the exit end face of the catheter body.

8. The spot tunable laser catheter of claim 1, wherein the catheter body comprises a fiber optic bundle coupled to the transmission core to receive the laser spot.

9. The laser catheter with the adjustable light spot according to claim 8, wherein the distance between the end face of the optical fiber bundle and the end face of the transmission core is less than 5um.

10. The adjustable-spot laser guide tube according to claim 1, wherein the laser emitter and the transmission core are coupled to each other through a focusing lens or a fiber fusion splice.