CN113425496A - Contact lens for treating fungal keratitis by administration - Google Patents
Contact lens for treating fungal keratitis by administration Download PDFInfo
- Publication number
- CN113425496A CN113425496A CN202110753247.0A CN202110753247A CN113425496A CN 113425496 A CN113425496 A CN 113425496A CN 202110753247 A CN202110753247 A CN 202110753247A CN 113425496 A CN113425496 A CN 113425496A
- Authority
- CN
- China
- Prior art keywords
- contact lens
- tablet
- contact
- piece
- fungal keratitis
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
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- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures
Abstract
The invention discloses a contact lens for drug delivery treatment of fungal keratitis, which comprises a contact lens, wherein one end of the contact lens is provided with a contact lens contact outer edge, one end of the contact lens contact outer edge is provided with a contact lens tablet bin, one end of the contact lens tablet bin is provided with a contact lens pupil contact piece, a contact lens inner piece is arranged in the contact lens, and one end of the contact lens inner piece is provided with a contact lens inner piece tablet layer; the contact lens tablet is soaked in the liquid medicine to absorb the treatment medicine, the contact lens inner piece is attached to the contact lens outer piece, the absorbed contact lens tablet is embedded into the contact lens tablet bin, the contact lens inner piece tablet layer is attached to the contact lens outer piece tablet layer, after the contact lens is worn into the eye, the medicine absorbed by the contact lens tablet is slowly released through the nanometer micropores, and the contact lens can be brought to each position of the eye along with blinking, so that the eye can be continuously treated.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to a contact lens for treating fungal keratitis by drug delivery.
Background
Fungal keratitis is an infectious keratopathy caused by pathogenic fungi with extremely high blindness rate. The fungal keratitis has slow onset and long course of disease, the course of disease can last for 2 to 3 months, and corneal ulcer usually appears within days of disease onset. In China, farmers have more patients; . More than 70 fungi have been found to cause corneal infections to date. Fungi are divided into two main categories, filamentous fungi and yeasts according to their different pathogenic effects in ocular infections.
Fungal keratitis is slow in onset, sub-acute in passing, mild in irritation symptom and accompanied with visual disturbance. The corneal infiltrative focus is white or grey, compact, dry in appearance and lusterless in surface, is toothpaste-like or fur-like in appearance, and is a gray raised focus (hypha coating) with clear boundary formed by hypha and necrotic tissue on the surface, sometimes pseudo-podia or satellite-like infiltrative focus is visible beside the corneal focus. The ulcer is surrounded by a shallow groove formed by collagen dissolution or an immune ring formed by antigen-antibody reaction, which is the reaction of the organism to the antigen and the antibody of fungi, and the corneal endothelial surface after the hypha focus is swollen and wrinkled, so that grey-white plaque-shaped deposits (endothelial spots) can be seen. Pus is collected in the anterior chamber, which is gray, sticky or pasty. The fungus has strong penetrability, and fungal endophthalmitis is easily caused when the fungus enters the anterior chamber or the cornea is punctured.
The fungal keratitis needs to be treated timely, and usually oral medicines or intraocular drops are used for treatment, but the treatment mode has poor continuous effect.
Disclosure of Invention
The present invention is directed to a contact lens for drug delivery treatment of fungal keratitis that solves the problems set forth in the background above.
In order to achieve the purpose, the invention provides the following technical scheme:
the utility model provides a contact lens for treating mycotic keratitis doses, includes the contact lens, contact lens one end is provided with the contact lens contact outside, contact lens contact outside one end is provided with contact lens tablet storehouse, contact lens tablet storehouse one end is provided with contact lens pupil contact piece, the inside contact lens inner piece that is provided with of contact lens, contact lens inner piece one end is provided with contact lens inner piece tablet layer, contact lens inner piece one end is provided with the contact lens outer piece, contact lens outer piece one end is provided with contact lens outer piece tablet layer, contact lens outer piece tablet layer inside is provided with nanometer micropore.
As a further scheme of the invention: and a contact lens tablet is arranged between the contact lens inner tablet layer and the contact lens outer tablet layer.
As a still further scheme of the invention: the contact outer edge of the contact lens, the contact lens tablet bin and the contact lens pupil contact piece are all formed by jointing the contact lens inner piece and the contact lens outer piece.
As a still further scheme of the invention: the contact lens tablet is located inside the contact lens tablet chamber.
As a still further scheme of the invention: the contact lens inner sheet is made of silicon hydrogel material with water content of fifty percent to fifty-five percent.
As a still further scheme of the invention: the contact lens outer sheet is made of a hydrogel material containing thirty to thirty-five percent of water.
As a still further scheme of the invention: the contact lens tablet is made of starch-based water-absorbing polymer materials.
As a still further scheme of the invention: the diameter of the contact lens is thirteen millimeters to fourteen millimeters.
As a still further scheme of the invention: the number of the nanometer micropores is provided with a plurality of groups, and the nanometer micropores are uniformly distributed in the contact lens outer tablet layer.
Compared with the prior art, the invention has the beneficial effects that:
1. according to the invention, the contact lens tablets are soaked in the liquid medicine to absorb the treatment medicine, the contact lens inner sheet is attached to the contact lens outer sheet, the absorbed contact lens tablets are embedded into the contact lens tablet bin, the contact lens inner sheet tablet layer is attached to the contact lens outer sheet tablet layer, after the contact lens is worn into the eye, the medicine absorbed by the contact lens tablets is slowly released through the nanometer micropores, and the contact lens is brought to each position of the eye along with blinking, so that the eye can be continuously treated.
2. The contact lens inner piece made of the fifty to fifty percent silicon hydrogel material with the water content is attached to the eyeball, so that the comfort can be effectively improved, and the contact lens outer piece made of the thirty to thirty percent silicon hydrogel material with the water content is positioned outside, so that the drying time of the contact lens can be prolonged, and the wettability of the contact lens can be kept.
Drawings
FIG. 1 is a schematic view of a contact lens for administration to treat fungal keratitis.
Fig. 2 is a schematic view of a contact lens for administration to treat fungal keratitis.
Fig. 3 is a schematic cross-sectional view of a contact lens for administration to treat fungal keratitis.
In the figure: 1-contact lens, 2-contact lens contact outside, 3-contact lens cartridge, 4-contact lens pupil contact, 5-contact lens inner, 6-contact lens inner, 7-contact lens outer, 8-contact lens outer, 9-nano-micro-pore, 10-contact lens tablet.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1 to 3, in an embodiment of the invention, a contact lens for drug administration treatment of fungal keratitis includes a contact lens 1, a contact lens contact outer edge 2 is disposed at one end of the contact lens 1, a contact lens tablet chamber 3 is disposed at one end of the contact lens contact outer edge 2, a contact lens pupil contact piece 4 is disposed at one end of the contact lens tablet chamber 3, a contact lens inner piece 5 is disposed inside the contact lens 1, a contact lens inner piece tablet layer 6 is disposed at one end of the contact lens inner piece 5, a contact lens outer piece 7 is disposed at one end of the contact lens inner piece 5, a contact lens outer piece tablet layer 8 is disposed at one end of the contact lens outer piece 7, and nano-micro-pores 9 are disposed inside the contact lens outer piece tablet layer 8.
Example one
A contact lens tablet 10 is arranged between the contact lens inner tablet layer 6 and the contact lens outer tablet layer 8, the contact lens tablet 10 is made of starch-based water-absorbent polymer materials, and the contact lens tablet 10 is positioned inside the contact lens tablet bin 3.
Example two
The contact lens contact outer edge 2, the contact lens tablet bin 3 and the contact lens pupil contact piece 4 are all formed by jointing a contact lens inner piece 5 and a contact lens outer piece 7.
EXAMPLE III
The contact lens inner sheet 5 is made of silicon hydrogel material with the water content of fifty percent to fifty percent, and the contact lens outer sheet 7 is made of silicon hydrogel material with the water content of thirty percent to thirty percent.
Example four
The diameter of the contact lens 1 is thirteen millimeters to fourteen millimeters.
EXAMPLE five
The number of the nanometer micropores 9 is provided with a plurality of groups, and the nanometer micropores are uniformly distributed in the contact lens outer tablet layer 8.
The working principle of the invention is as follows: soaking the contact lens tablets 10 in the liquid medicine to absorb the treatment medicine, attaching the contact lens inner sheet 5 and the contact lens outer sheet 7, embedding the absorbed contact lens tablets 10 into the contact lens tablet bin 3, attaching the contact lens inner sheet tablet layer 6 and the contact lens outer sheet tablet layer 8 to the contact lens tablets 10, putting the contact lens 1 into the eyes, the medicine absorbed by the contact lens tablet 10 is slowly released through the nano-micropores 9, and can be continuously treated as the eye blinks and is brought to each position of the eye, and the contact lens inner sheet 5 made of the pentadecasiloxane hydrogel material with the water content of fifty percent to fifty percent is attached to the eyeball, so that the comfort can be effectively improved, and the contact lens outer sheet 7 made of the thirty to thirty-five percent silicone hydrogel material with the water content is positioned outside, so that the drying time of the lens can be prolonged, and the wettability of the lens can be kept.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (9)
1. A contact lens for the treatment of fungal keratitis comprising a contact lens (1), characterized in that one end of the contact lens (1) is provided with a contact lens contact outer edge (2), one end of the contact outer edge (2) of the contact lens is provided with a contact lens tablet bin (3), one end of the contact lens tablet bin (3) is provided with a contact lens pupil contact piece (4), a contact lens inner sheet (5) is arranged in the contact lens (1), one end of the contact lens inner sheet (5) is provided with a contact lens inner sheet medicine layer (6), one end of the contact lens inner sheet (5) is provided with a contact lens outer sheet (7), one end of the contact lens outer piece (7) is provided with a contact lens outer piece tablet layer (8), the contact lens outer piece tablet layer (8) is internally provided with nano micropores (9).
2. The contact lens for administration in the treatment of fungal keratitis as claimed in claim 1, wherein a contact lens tablet (10) is disposed between the contact lens inner tablet layer (6) and the contact lens outer tablet layer (8).
3. The contact lens for drug delivery treatment of fungal keratitis as claimed in claim 1, wherein the contact lens contact outer edge (2), the contact lens cartridge (3) and the contact lens pupil contact piece (4) are all formed by jointing the contact lens inner piece (5) and the contact lens outer piece (7).
4. The contact lens for the administration of a drug for the treatment of fungal keratitis as claimed in claim 2, wherein the contact lens tablet (10) is located inside the contact lens cartridge (3).
5. The contact lens for the administration of drugs for the treatment of fungal keratitis as claimed in claim 1, wherein the contact lens inner sheet (5) is of a silicone hydrogel material having a water content of fifty to fifty-five percent.
6. The contact lens for the administration of drugs for the treatment of fungal keratitis as claimed in claim 1, wherein the contact lens outer sheet (7) is of a hydrogel material containing thirty to thirty-five percent of water.
7. The contact lens for the treatment of fungal keratitis as claimed in claim 2, wherein the contact lens tablet (10) is made of a starch-based water-absorbent polymer material.
8. The contact lens for administration in the treatment of fungal keratitis as claimed in claim 1, wherein the contact lens (1) has a diameter gauge of thirteen to fourteen millimeters.
9. The contact lens for drug delivery to treat fungal keratitis as claimed in claim 1, wherein the number of the nano-micropores (9) is provided with a plurality of groups which are uniformly distributed in the contact lens outer sheet layer (8).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110753247.0A CN113425496A (en) | 2021-07-02 | 2021-07-02 | Contact lens for treating fungal keratitis by administration |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110753247.0A CN113425496A (en) | 2021-07-02 | 2021-07-02 | Contact lens for treating fungal keratitis by administration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113425496A true CN113425496A (en) | 2021-09-24 |
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ID=77758844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110753247.0A Pending CN113425496A (en) | 2021-07-02 | 2021-07-02 | Contact lens for treating fungal keratitis by administration |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113425496A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107951618A (en) * | 2017-12-08 | 2018-04-24 | 华中科技大学 | A kind of contact lenses for drug treatment fungal keratitis |
| KR101877031B1 (en) * | 2016-12-30 | 2018-07-11 | 주식회사 윈스 | drug-loaded contact lens |
| US20200138702A1 (en) * | 2018-11-06 | 2020-05-07 | Korea Institute Of Science And Technology | Smart contact lens for non-invasive drug delivery |
| CN211043849U (en) * | 2019-08-01 | 2020-07-17 | 海昌隐形眼镜有限公司 | Hard contact lens |
| CN212808822U (en) * | 2020-08-07 | 2021-03-26 | 首都医科大学附属北京同仁医院 | Corneal contact lens |
-
2021
- 2021-07-02 CN CN202110753247.0A patent/CN113425496A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101877031B1 (en) * | 2016-12-30 | 2018-07-11 | 주식회사 윈스 | drug-loaded contact lens |
| CN107951618A (en) * | 2017-12-08 | 2018-04-24 | 华中科技大学 | A kind of contact lenses for drug treatment fungal keratitis |
| US20200138702A1 (en) * | 2018-11-06 | 2020-05-07 | Korea Institute Of Science And Technology | Smart contact lens for non-invasive drug delivery |
| CN211043849U (en) * | 2019-08-01 | 2020-07-17 | 海昌隐形眼镜有限公司 | Hard contact lens |
| CN212808822U (en) * | 2020-08-07 | 2021-03-26 | 首都医科大学附属北京同仁医院 | Corneal contact lens |
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