CN113384655A - Traditional Chinese medicine for preventing and treating phlebitis caused by infusion - Google Patents

Traditional Chinese medicine for preventing and treating phlebitis caused by infusion Download PDF

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Publication number
CN113384655A
CN113384655A CN202010169612.9A CN202010169612A CN113384655A CN 113384655 A CN113384655 A CN 113384655A CN 202010169612 A CN202010169612 A CN 202010169612A CN 113384655 A CN113384655 A CN 113384655A
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China
Prior art keywords
parts
traditional chinese
chinese medicine
infusion
preventing
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CN202010169612.9A
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Chinese (zh)
Inventor
何刘鑫
熊丹
何孙香
黎余余
侯延军
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides a traditional Chinese medicine for preventing and treating phlebitis caused by infusion, which belongs to the technical field of traditional Chinese medicines and comprises the following raw materials in parts by weight: 6-10 parts of ephedra, 6-10 parts of divaricate saposhnikovia root, 6-10 parts of safflower, 6 parts of rhubarb and 6-10 parts of bletilla striata; adopts a pure traditional Chinese medicine formula, has no stimulation and harm to the body and the skin, and has good effect.

Description

Traditional Chinese medicine for preventing and treating phlebitis caused by infusion
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine for preventing and treating phlebitis caused by infusion.
Background
Clinically, infusion is an indispensable treatment means for treating diseases, complications such as phlebitis are most easily generated in the infusion process, pain is often brought to patients, and the treatment period of the patients is even prolonged. The main clinical manifestations of phlebitis include: mild individuals may present with localized pain, redness of the skin along the superficial venular run, or pigmentation, and the skin around the vein may be itchy or swollen; septic phlebitis may occur in severe cases. At present, cold compress and magnesium sulfate external application are generally adopted clinically, gentamicin external application and other means are used by severe people, and no better means is provided for preventing and treating phlebitis caused by infusion. Particularly, the drugs with larger irritation to blood vessels are often interrupted due to the occurrence of phlebitis, so that the treatment period of a patient is prolonged.
Disclosure of Invention
Aiming at the technical defects, the invention aims to provide the traditional Chinese medicine for preventing and treating phlebitis caused by infusion.
In order to solve the technical problems, the invention adopts the following technical scheme:
the traditional Chinese medicine for preventing and treating phlebitis caused by infusion is characterized by comprising the following raw materials in parts by weight: 6-10 parts of ephedra, 6-10 parts of divaricate saposhnikovia root, 6-10 parts of safflower, 6 parts of rhubarb and 6-10 parts of bletilla striata.
The preparation and use method comprises the following steps: pulverizing the above Chinese medicinal materials into powder, adding oleum Sesami and 50% alcohol, concocting into paste, soaking with two layers of gauze, applying on local part, covering with film for 20-30 min, and performing 1-2 times daily with good effect.
The invention has the beneficial effects that: the traditional Chinese medicine adopts a pure traditional Chinese medicine formula, has no stimulation and harm to the body and the skin, and has good effect.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A traditional Chinese medicine for preventing and treating phlebitis caused by infusion comprises the following raw materials in parts by weight: 6 parts of ephedra, 8 parts of divaricate saposhnikovia root, 7 parts of safflower, 6 parts of rhubarb and 9 parts of bletilla striata, the raw materials are pulverized into powder, and sesame oil and 50% alcohol are added to be blended into thin paste.
Example 2
A traditional Chinese medicine for preventing and treating phlebitis caused by infusion comprises the following raw materials in parts by weight: 7 parts of ephedra, 9 parts of divaricate saposhnikovia root, 10 parts of safflower, 6 parts of rhubarb and 6 parts of bletilla striata, the raw materials are pulverized into powder, and sesame oil and 50% alcohol are added to be blended into thin paste.
Example 3
A traditional Chinese medicine for preventing and treating phlebitis caused by infusion comprises the following raw materials in parts by weight: 9 parts of ephedra, 7 parts of divaricate saposhnikovia root, 8 parts of safflower, 6 parts of rhubarb and 8 parts of bletilla striata, the raw materials are pulverized into powder, and sesame oil and 50% alcohol are added to be blended into thin paste.
And (3) observation of clinical experiments:
the invention carries out clinical observation and treatment on more than 2000 patients, the patients are male and female patients of all ages, the patients with the largest age are 90 years old, the patients with the smallest age are only 10 years old, and the patients are venous transfusion patients, have potential phlebitis risk, and can effectively prevent phlebitis.
The treatment method comprises the following steps:
the traditional Chinese medicine of embodiments 1 to 3 of the invention is externally applied, the raw materials are ground into powder, sesame oil and 50% alcohol are added to be mixed into thin paste, the paste is soaked by two layers of gauze and is applied to the part, and the film is covered and kept for 20 to 30 minutes for 1 to 2 times per day.
The evaluation standard of curative effect is as follows:
and (3) curing: the clinical signs disappeared.
Improvement: the clinical symptoms are obviously improved or improved.
And (4) invalidation: there was no improvement in clinical signs.
The treatment effect is as follows:
the external application is carried out for 5 days as a course of treatment, wherein patients with mild symptoms can be cured in 3 courses of treatment, and patients with severe symptoms can be cured in 5 courses of treatment. The traditional Chinese medicine for preventing and treating phlebitis caused by infusion has the effective rate of 95%, the cure rate of 70%, the improvement rate of 25% and the ineffective rate of 5%.
Typical case
Case 1: the patient Wangzhi, woman and 67 years old need hospitalization for later-stage lung cancer patients, the patient is subjected to anti-tumor treatment by using the Chinese patent medicine Kanglaite, the patient has symptoms and expressions of red gall in infusion veins, redness of skin in a superficial vein running region, pigmentation and the like after two days of infusion, the symptoms of the patient are obviously relieved after the patient is given the appeasing method for one treatment course, and the phlebitis expression does not appear after the patient continues to use the Kanglaite medicine.
Case 2: the patients are old, male and 48 years old, need to be hospitalized for chemotherapy treatment after the gastric cancer operation, and refuse to use deep vein catheterization transfusion, so a superficial vein transfusion mode is adopted, and the symptoms of skin redness, pain, pigmentation and the like appear in the traveling area along the superficial vein in the next day after the chemotherapy of the patients.
Case 3: patients need to be treated by transfusion in my family due to the disease condition, more than ninety percent of patients can have phlebitis according to the past experience due to the use of the sodium cantharidinate injection, so the method is externally applied to prevent the generation of phlebitis, and the patients do not have the generation of phlebitis within 28 days of transfusion.
The traditional Chinese medicine adopts a pure traditional Chinese medicine formula, has no stimulation and harm to the body and the skin, and has good effect.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims (1)

1. The traditional Chinese medicine for preventing and treating phlebitis caused by infusion is characterized by comprising the following raw materials in parts by weight: 6-10 parts of ephedra, 6-10 parts of divaricate saposhnikovia root, 6-10 parts of safflower, 6 parts of rhubarb and 6-10 parts of bletilla striata.
CN202010169612.9A 2020-03-12 2020-03-12 Traditional Chinese medicine for preventing and treating phlebitis caused by infusion Pending CN113384655A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010169612.9A CN113384655A (en) 2020-03-12 2020-03-12 Traditional Chinese medicine for preventing and treating phlebitis caused by infusion

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010169612.9A CN113384655A (en) 2020-03-12 2020-03-12 Traditional Chinese medicine for preventing and treating phlebitis caused by infusion

Publications (1)

Publication Number Publication Date
CN113384655A true CN113384655A (en) 2021-09-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010169612.9A Pending CN113384655A (en) 2020-03-12 2020-03-12 Traditional Chinese medicine for preventing and treating phlebitis caused by infusion

Country Status (1)

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CN (1) CN113384655A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101244174A (en) * 2008-02-22 2008-08-20 张景山 Pearl fumigation vascular gutron and preparation thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101244174A (en) * 2008-02-22 2008-08-20 张景山 Pearl fumigation vascular gutron and preparation thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李娜: "运用治未病理论预防肾病综合征三联疗法致浅静脉炎的效果观察", 《当代护士(下旬刊)》 *
许珍星: "自制护脉方中药塌渍对预防前列地尔注射致静脉炎的效果观察", 《当代医学》 *

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Application publication date: 20210914