CN113368337B - Device for delivering chemotherapeutic drugs - Google Patents
Device for delivering chemotherapeutic drugs Download PDFInfo
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- CN113368337B CN113368337B CN202110792856.7A CN202110792856A CN113368337B CN 113368337 B CN113368337 B CN 113368337B CN 202110792856 A CN202110792856 A CN 202110792856A CN 113368337 B CN113368337 B CN 113368337B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
Abstract
The invention discloses a device for delivering chemotherapeutic drugs, which comprises a liquid storage part, an air filtering mechanism, an automatic liquid stopper, a flow rate regulator and an injection needle which are sequentially connected through a delivery hose, and further comprises a delivery pressure regulating mechanism and a delivery pressure control mechanism, wherein the delivery pressure regulating mechanism comprises a first air pressure output end and a second air pressure output end, and the liquid storage part is connected with the first air pressure output end or the second air pressure output end through a pressure input part; the infusion pressure control mechanism comprises a low-pressure output end with the pressure smaller than the venous pressure, and when the delivery of the liquid medicine in the liquid storage part is finished, the infusion hose or the liquid storage part is communicated with the low-pressure output end. The device for infusing the chemotherapeutic drugs can provide two different air pressures for the infusion apparatus, so that the internal pressure of the infusion system can be adjusted under the condition that the height of the liquid storage part is not required to be adjusted, the requirement of partial chemotherapeutic drugs on the infusion time is met, and meanwhile, the air can be effectively prevented from entering the veins of a patient.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a device for delivering chemotherapeutic drugs.
Background
The chemotherapeutic medicine is used to treat pathogenic microbe, parasite, some autoimmune diseases and malignant tumor, and can kill tumor cell. The medicines can act on different links of growth and reproduction of tumor cells to inhibit or kill the tumor cells. Chemotherapy is one of the main means for treating tumor at present, and the chemotherapy needs to be precisely controlled, so that the chemotherapy not only has the effect of killing and inhibiting tumor cells, but also has great harm to normal cells, and at present, the common chemotherapy is an intravenous infusion method.
If the utility model is published under the number CN206577139U and named as 'a chemotherapy drug dosage quantitative input device', the published under the number 2017, 10, 24 and 24, the utility model comprises a quantitative metering tube and a liquid pumping mechanism, the quantitative metering tube is composed of a spiral hollow tube made of transparent material, the upper end of the quantitative metering tube is provided with a needle head for sucking the chemotherapy drugs, the side wall surface of the upper end tube wall of the quantitative metering tube is connected with a vent tube, the outer wall surface of the quantitative metering tube is sequentially provided with a plurality of scale marks for measuring the liquid volume from top to bottom, the vent tube is provided with a first water stop valve, the quantitative metering tube below the needle head is provided with a second water stop valve, the liquid pumping mechanism comprises a liquid containing cylinder, a piston, a fixed plate, a push rod and a corrugated rubber sleeve, the other end of the quantitative metering tube is communicated with the liquid containing cylinder, the piston is arranged in the liquid containing cylinder in a sliding way, the side surface of the piston is tightly attached to the inner wall surface of the liquid containing cylinder, the fixed plate is fixed with the other end of holding the liquid pipe, be provided with the screw hole on the fixed plate, be provided with on the pole wall of push rod with screw hole complex screw thread, the push rod passes through screw-thread fit and sets up on the fixed plate, the one end of piston is provided with the holding tank, the one end rotation of push rod sets up in the holding tank, the rubber sleeve cover is established on the fixed plate, the other end setting of push rod is provided with the drain pipe on the side of holding liquid section of thick bamboo upper end in the cavity that rubber sleeve and fixed plate formed, the drain pipe is provided with the third stagnant water valve. The utility model discloses an utilize the hollow tube to dispense in the patent, use the ration metering tube to carry out the liquid medicine and measure, carry out the venous transfusion to the chemotherapy medicine through the transfer line at last.
If the publication number is CN201235115Y, the name is "a combined chemotherapy infusion apparatus", the publication number is 2009, 5 months and 13 days of the utility model discloses a patent application, including puncture bottle needle A, intake pipe, branch flow regulator A, Murphy's dropper, total flow regulator, infusion filter, venous transfusion needle, puncture bottle needle B, branch flow regulator B constitutes, infusion hose one end is connected with parallelly connected puncture bottle needle A, puncture bottle needle B and intake pipe, the other end is connected with venous transfusion needle, the centre is equipped with Murphy's dropper, total flow regulator and infusion filter in proper order. The utility model discloses a during the patent is used, under closing the branch flow regulator state, use branch pipe B, patient can carry out the infusion of generality, if patient need inject the chemotherapy medicine when, temporarily close branch pipe B, stop ordinary infusion, then open branch flow regulator A, adjust the chemotherapy liquid medicine velocity of flow, the chemotherapy medicine just passes through branch pipe A, the Murphy's dropper, the total flow regulator, the infusion filter, among the vein infusion needle injection vein, thereby the effect of chemotherapy has been reached, the chemotherapy medicine drips the back, close branch flow regulator A, open branch flow regulator B ordinary infusion alright normally gone on.
In the actual operation process, part of the chemotherapy drugs need to be infused within a certain time, and the chemotherapy drugs need to be infused completely, in the prior art, the infusion rate is generally adjusted and controlled by adjusting the height of a flow regulator and an infusion bottle, but the infusion time cannot be controlled by the two adjustment modes in many cases, so that the chemotherapy drugs are delivered by a method of injecting the chemotherapy drugs by using an injector by medical staff in an intravenous injection manner under necessary conditions, the injection method has high requirements on the medical staff, the inconsistent injection speed of the drugs easily occurs, and the symptoms of pain, swelling and the like are caused to patients, so that the medical risk exists.
Disclosure of Invention
The invention aims to provide a device for infusing chemotherapeutic drugs, which aims to overcome the defects in the prior art.
In order to achieve the above purpose, the invention provides the following technical scheme:
a device for infusing chemotherapeutic drugs comprises a liquid storage part, an air filtering mechanism, an automatic liquid stopper, a flow rate regulator and an injection needle which are sequentially connected through an infusion hose, and further comprises an infusion pressure regulating mechanism and an infusion pressure control mechanism, wherein the infusion pressure regulating mechanism comprises a first air pressure output end and a second air pressure output end, and the liquid storage part is connected with the first air pressure output end or the second air pressure output end through a pressure input part;
the infusion pressure control mechanism comprises a low-pressure output end with the pressure smaller than the venous pressure, and when the delivery of the liquid medicine in the liquid storage part is finished, the infusion hose or the liquid storage part is communicated with the low-pressure output end.
In the device for delivering chemotherapeutic drugs, the air pressure at the first air pressure output end is greater than the air pressure at the second air pressure output end, and the low pressure output end is the first air pressure output end.
The infusion pressure adjusting mechanism of the device for infusing the chemotherapeutic drugs further comprises an adjusting piece, and the adjusting piece is used for adjusting the pressure input piece to be communicated with the first air pressure output end or the second air pressure output end.
The pressure input part of the chemotherapy drug infusion device comprises an air inlet part arranged on the liquid storage part.
The pressure input part of the device for infusing the chemotherapeutic drugs comprises a connecting part arranged on the infusion hose, and the liquid storage part is connected with the first air pressure output end or the second air pressure output end through the connecting part.
The infusion pressure control mechanism of the device for infusing the chemotherapeutic drugs comprises an automatic adjusting piece which automatically opens or closes the low-pressure output end along with the change of the infusion liquid level.
The infusion pressure control mechanism of the device for infusing the chemotherapeutic drugs comprises a liquid medicine caching piece, and a liquid medicine cavity of the liquid medicine caching piece is communicated with the infusion hose through a liquid inlet channel;
the automatic regulating part is arranged in the liquid medicine cavity, and a sealing part capable of automatically opening or closing the liquid inlet channel is arranged on the automatic regulating part.
According to the chemotherapy drug delivery device, a magnetic connecting piece is arranged between the automatic adjusting piece and the low-voltage output end, and when the low-voltage output end is closed, the automatic adjusting piece is attached to the low-voltage output end through the magnetic connecting piece.
The automatic liquid stopper of the chemotherapy drug transfusion device comprises a liquid inlet cavity and a liquid outlet cavity, wherein liquid stopping films with at least two apertures are arranged between the liquid inlet cavity and the liquid outlet cavity.
The automatic liquid stopper of the device for infusing the chemotherapeutic drugs is provided with a control part which can regulate and control the liquid medicine to pass through one, two or more liquid stopping films.
In the technical scheme, the device for infusing the chemotherapeutic drugs provided by the invention has the following beneficial effects:
the device for delivering the chemotherapeutic drugs comprises a liquid storage part, an air filtering mechanism, an automatic liquid stopper, a flow rate regulator and an infusion device formed by an injection needle which are sequentially connected through an infusion hose, and is also provided with a fluid delivery pressure regulating mechanism, wherein the fluid delivery pressure regulating mechanism is provided with a first air pressure output end and a second air pressure output end which have different air pressures, so that two different air pressures can be provided for the infusion device, the internal pressure of the infusion system can be regulated under the condition that the height of the liquid storage part is not required to be regulated, the requirement of partial chemotherapeutic drugs on the drug delivery time is met, and the delivery of liquid drugs is ensured to be completed within the specified time.
According to the device for delivering the chemotherapeutic drugs, provided by the embodiment of the invention, after the chemotherapeutic drugs in the liquid storage part are delivered through the fluid delivery control mechanism, the fluid delivery pressure regulating mechanism is cut off to provide high pressure for the infusion apparatus, so that the infusion apparatus is connected with the low-pressure output end of the fluid delivery control mechanism, the air pressure of the low-pressure output end is smaller than the venous pressure, so that the liquid medicine in the infusion apparatus cannot be completely delivered into the veins of a patient, and part of the liquid medicine is always positioned in the infusion hose under the action of the pressure difference between the venous pressure and the low-pressure output end, so that the air is effectively prevented from entering the veins of the patient.
Drawings
In order to more clearly illustrate the embodiments of the present application or technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present invention, and other drawings can be obtained by those skilled in the art according to the drawings.
FIG. 1 is a schematic structural diagram of a device for delivering chemotherapeutic agents according to an embodiment of the present invention;
fig. 2 is a schematic structural view of an infusion pressure adjusting mechanism according to an embodiment of the present invention;
FIG. 3 is a schematic structural diagram of an adjusting member according to an embodiment of the present invention;
FIG. 4 is a schematic structural diagram of a hydraulic pressure control mechanism according to another embodiment of the present invention;
FIG. 5 is a schematic structural diagram of a magnetic connector according to another embodiment of the present invention;
FIG. 6 is a schematic structural view of a ring plate according to another embodiment of the present invention;
FIG. 7 is a schematic structural view of a buoyancy opening structure provided in accordance with another embodiment of the present invention;
FIG. 8 is a schematic structural diagram of an automatic liquid stopper according to yet another embodiment of the present invention;
FIG. 9 is a schematic structural view of a vertical partition according to still another embodiment of the present invention;
fig. 10 is a schematic structural view of a buoyancy structure according to still another embodiment of the present invention.
Description of reference numerals:
1. an infusion set;
1.1, a transfusion hose; 1.2, an air filtering mechanism; 1.3, a flow rate regulator; 1.4, an injection needle;
2. a liquid storage member;
3. an automatic liquid stopping device;
3.1, a liquid inlet cavity; 3.2, a liquid outlet cavity; 3.3, stopping the liquid film; 3.4, a buoyancy structure; 3.5, adjusting a rod; 3.6, vertical partition boards; 3.6.1, through holes; 3.7, an air exhaust part; 3.8 air delivery section
4. A transfusion pressure adjusting mechanism;
4.1, a first air pressure output end; 4.2, a second air pressure output end; 4.3, a pressure cavity; 4.4, adjusting parts; 4.5, a round fixing plate; 4.6, a circular rotating plate; 4.7, sealing the soft film; 4.8, a sliding part; 4.9, driving the gear;
5. a pressure input;
6. a hydraulic pressure transmission control mechanism;
6.1, a low-voltage output end; 6.2, a liquid medicine caching piece; 6.3, a liquid medicine cavity; 6.4, a liquid inlet channel; 6.5, a buoyancy piece; 6.6, sealing element; 6.7, a buoyancy opening structure;
7. a magnetic connector;
7.1, a first magnetic part; 7.2, a second magnetic suction piece; 7.3, opening grooves; 7.4, a movable hole; 7.5, annular plates; 7.6, a movable column; 7.7, an elastic piece.
Detailed Description
In order to make the technical solutions of the present invention better understood, those skilled in the art will now describe the present invention in further detail with reference to the accompanying drawings.
As shown in fig. 1-10, an embodiment of the present invention provides a device for delivering chemotherapeutic drugs, including a liquid storage component 2, an air filtering mechanism 1.2, an automatic liquid stopper 3, a flow rate regulator 1.3, an injection needle 1.4, a fluid delivery pressure regulating mechanism 4 and a fluid delivery pressure controlling mechanism 6, which are sequentially connected through a fluid delivery hose 1.1, wherein the fluid delivery pressure regulating mechanism 4 includes a first air pressure output end 4.1 and a second air pressure output end 4.2, and the liquid storage component 2 is connected with the first air pressure output end 4.1 or the second air pressure output end 4.2 through a pressure input component 5; the hydraulic pressure delivery control mechanism 6 comprises a low-pressure output end 6.1 with the pressure smaller than the venous pressure, and when the delivery of the liquid medicine in the liquid storage part 2 is finished, the infusion hose 1.1 or the liquid storage part 2 is communicated with the low-pressure output end 6.1.
Specifically, the liquid storage part 2, the air filtering mechanism 1.2, the automatic liquid stopper 3, the flow rate regulator 1.3 and the injection needle 1.4 are sequentially connected through the infusion hose 1.1 to form the infusion apparatus 1, a channel between the liquid medicine and the vein is established through the infusion apparatus 1, the intravenous infusion of the chemotherapy medicine is realized, the infusion apparatus 1 can further comprise a needle head protective cap, a drip cup, a bottle plug puncture outfit, a liquid medicine filter and the like in the prior art, the flow rate regulator 1.3, the air filtering mechanism 1.2, the injection needle 1.4, the needle head protective cap, the drip cup, the bottle plug puncture outfit and the liquid medicine filter are medical equipment commonly used in the prior art, and are well known by those skilled in the art and are not described herein again. When chemotherapy drugs are delivered to a patient through the infusion apparatus 1, the delivery principle is as follows: when the internal pressure of the infusion system is greater than the venous pressure, the infusion apparatus 1 conveys the chemotherapeutic drug into the vein along the infusion hose 1.1, when the internal pressure of the infusion system is less than the venous pressure, the chemotherapeutic drug can not be conveyed into the vein, and meanwhile, the blood in the vein has the risk of flowing back to the infusion hose 1.1, in the prior art, the liquid medicine conveying is realized under the action of the atmospheric pressure, namely, the internal pressure of the infusion system is equal to the atmospheric pressure plus the hydrostatic pressure in the infusion apparatus 1, the hydrostatic pressure in the infusion apparatus 1 is the water column pressure formed by the height of the liquid medicine pressure surface in the liquid storage part 2 away from the puncture part, because the atmospheric pressure is fixed, when the internal pressure of the infusion system needs to be adjusted in the prior art, the hydrostatic pressure in the infusion apparatus 1 can be increased only by adjusting the height of the liquid storage part 2, but due to the limitations of the existing ward, place and height, the height of the infusion apparatus is limited, the height adjustment range of the liquid storage part 2 is limited, therefore, the hydrostatic pressure adjusting range in the infusion apparatus 1 is fixed, the infusion pressure adjusting mechanism 4 in the embodiment is used for providing two air pressures for the infusion apparatus 1, at least one air pressure in the first air pressure output end 4.1 and the second air pressure output end 4.2 is larger than the atmospheric pressure, so that the air pressure larger than the atmospheric pressure can be provided for the liquid storage part 2, the internal pressure of the infusion system can be adjusted without adjusting the height of the liquid storage part 2, the requirement of partial chemotherapy drugs on the drug delivery time is met, and the delivery of the drug liquid is ensured to be completed within the specified time.
In this embodiment, when the air pressure provided by the infusion pressure adjusting mechanism 4 is greater than the venous pressure, if the chemotherapy drug is delivered, the medical staff or the patient does not close the flow rate adjuster 1.3 in time, there is a risk of delivering air into the vein, in order to avoid this risk, the automatic liquid stopper 3 in the existing infusion apparatus 1 can be used, and the precise filtering device avoids its risk, in this embodiment, on the basis of the structure of the existing infusion apparatus 1, the infusion pressure control mechanism 6 is further provided, so as to realize multiple protection, and effectively avoid air from being delivered into the vein of the patient, after the infusion pressure control mechanism 6 is used for delivering the chemotherapy drug in the liquid storage part 2, the infusion pressure adjusting mechanism 4 is cut off to provide high pressure for the infusion apparatus 1, so that the infusion apparatus 1 is connected with the low-pressure output end 6.1 of the infusion pressure adjusting mechanism 6, and the air pressure at the low-pressure output end 6.1 is less than the venous pressure. Optionally, the pressure of the low-pressure output end 6.1 can be set according to the structure and height of the infusion apparatus 1, namely when the infusion apparatus 1 is connected with the low-pressure output end 6.1, the liquid medicine in the infusion apparatus 1 can not be completely conveyed into the vein of the patient, namely, under the action of the pressure difference between the venous pressure and the low-pressure output end 6.1, part of the liquid medicine is always positioned in the infusion hose 1.1, so that the air is effectively prevented from entering the vein of the patient.
In this embodiment, the liquid storage part 2 is used for storing chemotherapy drugs, the liquid storage part 2 and the infusion hose 1.1 may be integrally arranged, a puncture outfit may be arranged at an end of the infusion hose 1.1, the infusion hose 1.1 is communicated with the liquid storage part 2 through the puncture outfit, the liquid storage part 2 is further provided with identification scales, the chemotherapy drugs stored in the liquid storage part 2 can be measured through the identification scales, quantitative delivery of the chemotherapy drugs is achieved, the air filtering mechanism 1.2, the flow speed device, the automatic liquid stopper 3 and the injection needle 1.4 can all adopt the structure of the infusion apparatus 1 in the prior art, the air filtering mechanism 1.2, the flow speed device, the automatic liquid stopper 3 and the injection needle 1.4 are all connected through the infusion hose 1.1, it should be noted that, in the device for delivering chemotherapy drugs in this embodiment, the structure sequentially connected on the infusion hose 1.1 is not limited to the above structure, a drip pot, a drip, A bottle stopper puncture outfit, a liquid medicine filter, an injection piece, a medicine adding port and the like.
In this embodiment, the infusion adjusting mechanism includes a first air pressure output end 4.1, a second air pressure output end 4.2 and an air pressure providing structure, the air pressure providing structure may be a pressure pump, the first air pressure output end 4.1 and the second air pressure output end 4.2 respectively provide two different air pressures, the air pressures output by the first air pressure output end 4.1 and the second air pressure output end 4.2 may both be greater than the atmospheric pressure, or one of the air pressures of the first air pressure output end 4.1 and the second air pressure output end 4.2 may be greater than the atmospheric pressure, and the other air pressure is equal to or less than the atmospheric pressure, when the first air pressure output end 4.1 or the second air pressure output end 4.2 is equal to the atmospheric pressure, it may be directly connected to the atmosphere at this time, and does not need to be connected to the air pressure providing structure. The regulating part 4.4 is arranged in the transfusion regulating mechanism, the opening and closing of the first air pressure output end 4.1 and the opening or closing of the second air pressure output end 4.2 are realized through the regulating part 4.4, the regulating part 4.4 can be an automatic opening valve or a manual opening valve, the first air pressure output end 4.1 and the second air pressure output end 4.2 are connected with the liquid storage part 2 through the pressure input part 5, the pressure input part 5 can be a structure arranged on the liquid storage part 2, such as a connecting port arranged on the liquid storage part 2, the pressure input part 5 can also be a structure arranged on the transfusion hose 1.1, such as a connecting port arranged on the transfusion hose 1.1, so that the transfusion pressure regulating mechanism 4 is communicated with the liquid storage part 2 through the transfusion hose 1.1, therefore, when various kinds of liquid medicines are delivered at one time, only the liquid storage part 2 needs to be replaced, and the transfusion pressure regulating mechanism 4 does not need to be reconnected, so that the operation is more convenient. Further, the liquid storage part 2 in this embodiment can be a liquid storage bottle or a liquid storage soft bag, when the liquid storage part 2 is a liquid storage bottle, the infusion pressure adjusting mechanism 4 is directly communicated with the liquid storage bottle through the pressure input part 5, namely, as the liquid level of the liquid medicine in the infusion bottle is lowered, the air is gradually input into the infusion bottle, the air pressure in the infusion bottle is kept consistent with the air pressure of the first air pressure output end 4.1 or the second air pressure output end 4.2, when the infusion part is a liquid storage soft bag, the pressure input part 5 comprises an inflatable bag, the liquid storage soft bag is placed inside the inflatable bag, the inflatable bag is communicated with the first air pressure output end 4.1 or the second air pressure output end 4.2, the air pressure of the inflatable bag is kept consistent with that of the first air pressure output end 4.1 or the second air pressure output end 4.2, and the pressure generated by the inflation of the inflatable bag is transmitted to the infusion soft bag wrapped inside, so that the liquid in the infusion soft bag flows out from the infusion hose 1.1.
In this embodiment, infusion pressure control mechanism 6 can set up in the inside of infusion pressure adjustment mechanism 4, also can set up on pressure input 5, low pressure output 6.1 can be the lower one of air pressure in first air pressure output 4.1 and the second air pressure output 4.2, so in normal infusion in-process, stock solution spare 2 is connected with the higher one of air pressure in first air pressure output 4.1 and the second air pressure output 4.2 through pressure input 5, after the liquid medicine has been carried in stock solution spare 2, stock solution spare 2 is connected with low pressure output 6.1 this moment, promptly stock solution spare 2 is connected with the lower one of air pressure in first air pressure output 4.1 and the second air pressure output 4.2 through pressure input 5. Optionally, infusion pressure control mechanism 6 can also be an independent mechanism, low pressure output 6.1 also can be an independent atmospheric pressure output structure that sets up, after the liquid medicine transport of stock solution spare 2 was accomplished, infusion pressure control mechanism 6 can be linked together with low pressure output 6.1 according to liquid level automatic control stock solution spare 2 or infusion hose 1.1 of liquid medicine, thereby make the atmospheric pressure in infusion hose 1.1 be less than the venous pressure, effectively avoid carrying the air to human vein after the liquid medicine transport is accomplished. The liquid conveying pressure control mechanism 6 can detect the liquid level of the liquid storage part 2 by a detection part or a sensor and the like, when the liquid conveying of the liquid storage part 2 is finished, the detection part or the sensor transmits a signal to the liquid conveying pressure control mechanism 6, the liquid conveying pressure control mechanism 6 enables the liquid storage part 2 or the liquid conveying hose 1.1 to be connected with the low-pressure output end 6.1,
the device for infusing the chemotherapeutics provided by the embodiment of the invention comprises an infusion apparatus 1 formed by a liquid storage part 2, an air filtering mechanism 1.2, an automatic liquid stopper 3, a flow rate regulator 1.3 and an injection needle 1.4 which are sequentially connected through an infusion hose 1.1, and is also provided with an infusion pressure regulating mechanism 4, wherein the infusion pressure regulating mechanism 4 is provided with a first air pressure output end 4.1 and a second air pressure output end 4.2 which have different air pressures, so that two different air pressures can be provided for the infusion apparatus 1, the internal pressure of an infusion system can be regulated under the condition that the height of the liquid storage part 2 does not need to be regulated, the requirement of partial chemotherapeutics on the infusion time is met, and the delivery of liquid medicines is ensured to be completed within the specified time.
According to the device for delivering the chemotherapeutic drug, provided by the embodiment of the invention, after the chemotherapeutic drug in the liquid storage part 2 is delivered, the delivery hydraulic control mechanism 6 cuts off the delivery hydraulic adjustment mechanism 4 to provide high pressure for the infusion apparatus 1, so that the infusion apparatus 1 is connected with the low-pressure output end 6.1 of the infusion pressure control mechanism 6, as the air pressure of the low-pressure output end 6.1 is smaller than the venous pressure, the liquid medicine in the infusion apparatus 1 cannot be completely delivered into the vein of a patient, and part of the liquid medicine is always positioned in the infusion hose 1.1 under the action of the pressure difference between the venous pressure and the low-pressure output end 6.1, so that air is effectively prevented from entering the vein of the patient.
In the embodiment provided by the invention, preferably, the air pressure of the first air pressure output end 4.1 is greater than the air pressure of the second air pressure output end 4.2, and the low pressure output end 6.1 is the first air pressure output end 4.1; the air pressure of the first air pressure output end 4.1 is greater than the atmospheric pressure, the air pressure of the second air pressure output end 4.2 is less than the venous pressure, and the air pressure of the second air pressure output end 4.2 can be greater than the atmospheric pressure, and can also be equal to or less than the atmospheric pressure, when the infusion pressure control mechanism 6 is arranged inside the infusion pressure adjusting mechanism 4 or the pressure input part 5, the low pressure output end 6.1 is directly the second air pressure output end 4.2, when the infusion pressure control mechanism 6 is an independent structure, the low pressure output end 6.1 is communicated with the second air pressure output end 4.2, namely the low pressure output end 6.1 and the second air pressure output end 4.2 share one air pressure providing structure, when the second air pressure output end 4.2 is the same as the atmospheric pressure, the low pressure output end 6.1 and the second air pressure output end 4.2 are the atmospheric pressure, and the second air pressure output end 4.2 and the low pressure output end 6.1 are directly communicated with the atmosphere.
In the embodiment provided by the invention, further, the infusion pressure adjusting mechanism 4 further comprises an adjusting part 4.4 for adjusting the communication between the pressure input part 5 and the first air pressure output end 4.1 or the second air pressure output end 4.2; the adjusting part 4.4 can open or close the first air pressure output end 4.1 and can also open or close the second air pressure output end 4.2, namely the adjusting part 4.4 adjusts and controls to realize that the pressure input part 5 can be communicated with the first air pressure output end 4.1, and the adjusting part 4.4 adjusts and controls to realize that the pressure input part 5 can be communicated with the second air pressure output end 4.2, so that the liquid storage part 2 can be selectively connected with the first air pressure output end 4.1 or the second air pressure output end 4.2.
In the embodiment provided by the present invention, preferably, the infusion pressure adjusting mechanism 4 includes a pressure chamber 4.3, one side of the pressure chamber 4.3 is provided with an air outlet, the air outlet is communicated with the pressure input member 5, the other side of the pressure chamber 4.3 is connected with the first air pressure output end 4.1 and the second air pressure output end 4.2, the adjusting member 4.4 realizes that the pressure chamber 4.3 is communicated with the first air pressure output end 4.1 or communicated with the second air pressure output end 4.2, the adjusting member 4.4 can be an automatic opening valve or a manual opening valve arranged on the first air pressure output end 4.1 and the second air pressure output end 4.2, the first air pressure output end 4.1 and the second air pressure output end 4.2 of the present embodiment are both provided with an adjusting member 4.4, the adjusting member 4.4.4 includes a circular fixing plate 4.5 and a circular rotating plate 4.6, the circular fixing plate 4.5 is arranged along the radial direction of the first air pressure output end 4.1 and the second air pressure output end 4.2, the circular fixing plate 4.5 is provided with a communicating part, the circular rotating plate 4.6 is rotatably connected to the circular fixing plate 4.5, an opening portion and a sealing portion are arranged on the circular rotating plate 4.6, when the opening portion corresponds to the communicating portion in the rotating process of the circular rotating plate 4.6, the communicating portion is opened to be communicated with the pressure cavity 4.3, when the sealing portion corresponds to the communicating portion, the communicating portion is closed, the communicating portion can be a communicating opening or a communicating hole 3.6.1, and the opening portion and the sealing portion are arranged corresponding to the communicating portion. Meanwhile, a driving part is arranged on the side wall of the pressure cavity 4.3 and used for driving the circular rotating plate 4.6 to rotate, the driving part can be a driving gear 4.9, a sawtooth part is arranged on the circular rotating plate 4.6, and the driving gear 4.9 is meshed with the sawtooth part, so that the driving gear 4.9 is driven by a hand to rotate to correspondingly drive the circular rotating plate 4.6 to rotate, and the communication part is correspondingly adjusted and controlled to be opened or closed. Further, in order to improve the sealing performance between the driving element and the pressure chamber 4.3, a sealing element 6.6 is arranged between the driving element and the pressure chamber 4.3, the sealing element 6.6 may be a sealing soft film 4.7, two ends of the sealing soft film 4.7 are provided with sliding elements 4.8, a sliding groove for the sliding elements 4.8 to slide back and forth is arranged in the pressure chamber 4.3, the sealing soft film 4.7 is positioned between the driving gear 4.9 and the saw-tooth portions, the sliding element 4.8 may be provided with a roll receiving element capable of receiving and releasing the sealing soft film 4.7, or the sliding element 4.8 may be provided with an elastic element 7.7 to limit the sliding stroke of the sliding element 4.8, so that when the driving gear 4.9 rotates, the sealing soft film 4.7 and the saw-tooth portions are driven to move simultaneously, thereby improving the sealing performance between the driving element and the pressure chamber 4.3.
In the embodiment provided by the present invention, preferably, the pressure input member 5 includes an air inlet portion provided on the liquid storage member 2; the air inlet portion can be an air inlet hole or an air inlet hose, the air inlet portion is communicated with the infusion pressure adjusting mechanism 4, the air inlet portion can be adjusted and controlled to be communicated with the first air pressure output end 4.1 or the second air pressure output end 4.2 through the adjusting piece 4.4, and therefore air pressure in the liquid storage piece 2 is the same as air pressure of the first air pressure output end 4.1 or the second air pressure output end 4.2.
In the embodiment provided by the invention, preferably, the pressure input part 5 comprises a connecting part arranged on the infusion hose 1.1, and the liquid storage part 2 is connected with the first air pressure output end 4.1 or the second air pressure output end 4.2 through the connecting part. The connecting piece can be the connector, connecting pipe or other structure, the connecting piece is linked together with infusion pressure adjustment mechanism 4, the adjustable control connecting piece of regulating part 4.4 is linked together with first atmospheric pressure output 4.1 or second atmospheric pressure output 4.2, so make first atmospheric pressure output 4.1 or second atmospheric pressure output 4.2 be linked together with stock solution spare 2 through connecting piece and infusion hose 1.1, so when the liquid medicine transport of a stock solution spare 2 is accomplished and is needed to be changed, only need be connected infusion hose 1.1 and stock solution spare 2 and just can continue to use, need not install and dismantle infusion adjustment mechanism, increase the convenience of using.
In another embodiment provided by the invention, the infusion pressure control mechanism 6 preferably comprises an automatic regulating element 4.4 which automatically opens or closes the low pressure output 6.1 as the infusion level changes. Automatic regulating part 4.4 can be the detection piece that can detect the infusion liquid level, at low pressure output 6.1, all set up an automatic opening valve on first atmospheric pressure output 4.1 and the second atmospheric pressure output 4.2, after the liquid medicine that detects in stock solution spare 2 was carried to the detection piece, automatic opening valve automatically opened low pressure output 6.1, automatic opening valve closes first atmospheric pressure output 4.1 and second atmospheric pressure output 4.2 simultaneously, make low pressure output 6.1 be linked together with infusion hose 1.1 or stock solution spare 2.
In another embodiment provided by the present invention, preferably, the infusion pressure control mechanism 6 includes a liquid medicine buffer storage piece 6.2, and a liquid medicine cavity 6.3 of the liquid medicine buffer storage piece 6.2 is communicated with the infusion hose 1.1 through a liquid inlet channel 6.4; the automatic regulating part 4.4 is arranged in the liquid medicine cavity 6.3, and a sealing part 6.6 which can automatically open or close the liquid inlet channel 6.4 is arranged on the automatic regulating part 4.4; the upper end of the liquid medicine cavity 6.3 is connected with the transfusion hose 1.1 through the liquid inlet channel 6.4, the liquid outlet at the lower end of the liquid medicine cavity 6.3 is also connected with the transfusion hose 1.1, the low-pressure output end 6.1 is positioned at the side part of the liquid medicine cavity 6.3, the low-pressure output end 6.1 is also communicated with the liquid medicine cavity 6.3, the automatic adjusting piece 4.4 is connected in the liquid medicine cavity 6.3 in a sliding way, the automatic adjusting piece 4.4 comprises a buoyancy piece 6.5, the sealing piece 6.6 is connected with the buoyancy piece 6.5 through a connecting structure, the buoyancy opening structure 6.7 capable of opening or closing the low-pressure output end 6.1 is arranged on the buoyancy piece 6.5, the buoyancy opening structure 6.7 can be a sealing plate or a sealing ball and the like which are arranged corresponding to the low-pressure output end 6.1, so that in the starting process, liquid medicine flows into the liquid medicine cavity 6.3 from the liquid medicine cavity 1.1 under the manual action of medical staff, the buoyancy opening structure 6.5 moves upwards along with the rising liquid medicine cavity 6.3, thereby closing the buoyancy opening mechanism, liquid inlet channel 6.4 is opened to sealing member 6.6, after the liquid medicine in stock solution spare 2 is carried and is accomplished, the liquid medicine liquid level in liquid medicine chamber 6.3 continues to descend, thereby make buoyancy spare 6.5 downstream, sealing member 6.6 closes liquid inlet channel 6.4 this moment, then buoyancy opening mechanism opens low pressure output 6.1, make liquid medicine chamber 6.3 and infusion hose 1.1 that is located liquid medicine chamber 6.3 below be linked together with low pressure output 6.1, because the atmospheric pressure of low pressure output 6.1 is less than the vein pressure, effectively avoid air transportation to patient's vein, after changing stock solution spare 2, continue the infusion through manual operation.
In another embodiment provided by the invention, optionally, a magnetic connecting piece 7 is arranged between the automatic adjusting piece 4.4 and the low-voltage output end 6.1, and when the low-voltage output end 6.1 is closed, the automatic adjusting piece 4.4 is attached to the low-voltage output end 6.1 through the magnetic connecting piece 7; the magnetic connecting piece comprises a first magnetic piece 7.1 and a second magnetic piece 7.2 with different magnetism, the first magnetic piece 7.1 is arranged on the side wall of the buoyancy opening structure 6.7 close to the low-pressure output end 6.1, the first magnetic piece 7.1 is arranged from the top to the bottom of the buoyancy opening structure 6.7 in sequence, the second magnetic piece 7.2 is connected on the side wall of the low-pressure output end 6.1 through a movable piece and an elastic piece 7.7, one side of the low-pressure output end 6.1 close to the liquid medicine cavity 6.3 is provided with an open slot 7.3, a movable hole 7.4 is arranged in the open slot 7.3, the movable piece comprises a ring plate 7.5 and a movable column 7.6 connected on the ring plate 7.5, the second magnetic piece 7.2 is arranged on the ring plate 7.5, the movable column 7.6 is connected inside the movable hole 7.4 in a sliding manner, the ring plate 7.5 is movably connected in the open slot 7.3, the elastic piece 7.7 is sleeved on the column 7.6, the elastic piece 7.7 can be fixedly limited in the magnetic piece or movably in the open slot 7.3, the second magnetic piece 7.2, under the effect of magnetic attraction and elastic component 7.7, the piece is inhaled mutually with first magnetism to second magnetism 7.2 to make the annular plate 7.5 closely laminate and fix on the lateral wall that the structure 6.7 was opened to buoyancy, thereby increase the sealed effect when low pressure output 6.1 closed.
In another embodiment provided by the present invention, preferably, the automatic liquid stopper 3 includes a liquid inlet chamber 3.1 and a liquid outlet chamber 3.2, and a liquid stopping membrane 3.3 with at least two apertures is disposed between the liquid inlet chamber 3.1 and the liquid outlet chamber 3.2. The liquid stopping membrane 3.3 is an ultrafiltration membrane or a nuclear pore filter membrane and the like, can filter liquid medicine under very small pressure, the liquid stopping membrane 3.3 is arranged inside the automatic liquid stopping device 3 along the vertical direction, the liquid stopping membrane 3.3 separates the automatic liquid stopping device 3 into a liquid outlet cavity 3.2 and a liquid inlet cavity 3.1 at the left side and the right side, the liquid inlet cavity 3.1 is communicated with the infusion hose 1.1 so as to receive the liquid medicine conveyed from the infusion hose 1.1, and the bottom of the liquid outlet cavity 3.2 is connected with the infusion hose 1.1 so as to output the filtered liquid medicine. At least two liquid stopping films 3.3 or a plurality of liquid stopping films 3.3 with different apertures are arranged in sequence from top to bottom in the automatic liquid stopper 3, and the pore diameter of the liquid stopping membrane 3.3 is gradually increased from the bottom to the top, the liquid stopping membranes 3.3 with different pore diameters can realize the filtration of insoluble particles with different diameters, thus, the liquid stopping membrane 3.3 with different apertures can be selected for filtration according to different delivered chemotherapeutic drugs, if the delivered chemotherapeutic drugs can pass through the liquid stopping membrane 3.3 with small apertures, the insoluble particles with smaller diameter can be filtered at the same time, the transfusion reaction caused in the transfusion process can be avoided, and after the transfusion is finished, because the capillary action of ending liquid film 3.3 can play the effect that blocks the air to make the air remain in feed liquor chamber 3.1, effectively avoid the air to carry to the patient from infusion hose 1.1 internal, realize the effect of automatic end liquid simultaneously.
In still another embodiment of the present invention, further, a control member is disposed on the automatic liquid stopper 3, the control member can regulate and control the liquid medicine to pass through one, two or more liquid stopping films 3.3, the control member includes a buoyancy structure 3.4 disposed in the liquid inlet cavity 3.1, the buoyancy structure 3.4 partitions the liquid inlet cavity 3.1 into an upper chamber and a lower chamber, the buoyancy structure 3.4 can ascend or descend along with the liquid level of the liquid medicine in the liquid inlet cavity 3.1, an adjusting rod 3.5 is disposed on the automatic liquid stopper 3, one end of the adjusting rod 3.5 is disposed in the liquid inlet cavity 3.1, the other end of the adjusting rod 3.5 is disposed outside the automatic liquid stopper 3 and is connected with an adjusting portion, the adjusting rod 3.5 is blocked in the movement stroke of the buoyancy structure 3.4, so that the length of the adjusting rod 3.5 disposed in the liquid inlet cavity 3.1 can be adjusted by the adjusting portion, thereby limiting the movement of the buoyancy structure 3.4, that the buoyancy structure 3.4 stops moving when being conveyed to the lower end of the adjusting rod 3.5, at this time, only the liquid stopping film 3.3 with the height lower than the lower end of the adjusting rod 3.5 can filter the liquid medicine, namely, the liquid medicine can only pass through the liquid stopping film 3.3 at one side of the cavity below the buoyancy structure 3.4, and the liquid stopping film 3.3 at one side of the cavity above the buoyancy structure can not pass through the liquid medicine.
In still another embodiment of the present invention, preferably, a vertical partition plate 3.6 is further disposed on the sidewall of the liquid inlet chamber 3.1, a flow rate control plate is disposed on the vertical partition plate 3.6, a plurality of sets of through holes 3.6.1 are sequentially disposed on the flow rate control plate from top to bottom, and in a direction from the top to the bottom of the vertical partition plate 3.6, the hole diameters of the through holes 3.6.1 are gradually reduced, the number of the through holes 3.6.1 is not changed or is gradually reduced in a direction from the top to the bottom of the vertical partition plate 3.6, two kinds of liquid stopping films 3.3 are disposed in the automatic liquid stopper 3, at least three kinds of through holes 3.6.1 having different hole diameters are correspondingly disposed on the lower liquid stopping film 3.3, the hole diameter of the uppermost through hole 3.6.1 is designed to satisfy the flow of the liquid medicine, the hole diameter of the lowermost through hole 3.6.1 is arranged to be horizontal to the lowermost through hole 3.6.1, when the liquid medicine in the liquid inlet chamber 3.1 is lowered to the position horizontal to the lowermost through hole 3.6.1, the liquid medicine in the liquid inlet cavity 3.1 is completely conveyed into the liquid outlet cavity 3.2, the process is called a liquid medicine overflowing process, and the time of the liquid medicine overflowing process is more than 30 minutes, so that long supervision time is provided for medical staff, and medical accidents are avoided. Because the aperture of the through hole 3.6.1 positioned at the lowest part is very small, the liquid medicine in the liquid inlet cavity 3.1 can slowly pass through the through hole 3.6.1, the liquid passing through the through hole 3.6.1 slowly seeps through the hydrophilic membrane, and the liquid stopping membrane 3.3 can gradually form a uniform liquid diaphragm due to the tension action of the liquid and the gas, so that the air can not enter through holes of the liquid stopping membrane 3.3 when the liquid supply by permeation is finished, and the functions of automatic liquid stopping and blood return prevention in the true sense are achieved.
In still another embodiment provided by the present invention, preferably, air discharging portions 3.7 are disposed at the top of the liquid inlet chamber 3.1 and the top of the liquid outlet chamber 3.2, a filter membrane is disposed on the air discharging portions 3.7, the air in the liquid inlet chamber 3.1 and the air in the liquid outlet chamber 3.2 can be discharged from the filter membrane, but the liquid medicine in the liquid inlet chamber 3.1 and the liquid outlet chamber 3.2 cannot be discharged from the filter membrane, an air conveying portion 3.8 is also disposed on the buoyancy structure 3.4, and a filter membrane is also disposed on the air conveying portion 3.8, so that the air can be conveyed from the chamber below the buoyancy structure 3.4 to the chamber above the buoyancy structure 3.4, and finally output from the air discharging portion 3.7.
While certain exemplary embodiments of the present invention have been described above by way of illustration only, it will be apparent to those of ordinary skill in the art that the described embodiments may be modified in various different ways without departing from the spirit and scope of the invention. Accordingly, the drawings and description are illustrative in nature and should not be construed as limiting the scope of the invention.
Claims (10)
1. A device for infusing chemotherapeutic drugs comprises a liquid storage part, an air filtering mechanism, an automatic liquid stopper, a flow rate regulator and an injection needle which are sequentially connected through an infusion hose, and is characterized by further comprising an infusion pressure regulating mechanism and an infusion pressure control mechanism, wherein the infusion pressure regulating mechanism comprises a first air pressure output end and a second air pressure output end, and the liquid storage part is connected with the first air pressure output end or the second air pressure output end through a pressure input part;
the infusion pressure control mechanism comprises a low-pressure output end with the pressure smaller than the venous pressure, and when the delivery of the liquid medicine in the liquid storage part is finished, the infusion hose or the liquid storage part is communicated with the low-pressure output end.
2. The device of claim 1, wherein the first pneumatic output is at a higher pressure than the second pneumatic output, and the low pressure output is the first pneumatic output.
3. The device of claim 1, wherein the infusion pressure adjustment mechanism further comprises an adjustment member for adjusting the pressure input member to communicate with the first or second pneumatic output.
4. A device for delivering a chemotherapeutic agent according to claim 1, wherein the pressure input comprises an air inlet disposed on the reservoir.
5. The device of claim 1, wherein the pressure input member comprises a connector disposed on the infusion tube, and the reservoir member is connected to the first or second pneumatic output via the connector.
6. The device for infusing chemotherapeutic agents of claim 1, wherein the fluid infusion control mechanism comprises an automatic regulator that automatically opens or closes the low pressure output port as the fluid level changes.
7. The device for infusing chemotherapeutic drugs according to claim 6, wherein the fluid infusion control mechanism comprises a drug solution buffer member, and a drug solution cavity of the drug solution buffer member is communicated with the infusion hose through a fluid inlet channel;
the automatic regulating part is arranged in the liquid medicine cavity, and a sealing part capable of automatically opening or closing the liquid inlet channel is arranged on the automatic regulating part.
8. The device of claim 6, wherein a magnetic connector is disposed between the automatic adjustment member and the low pressure output end, and when the low pressure output end is closed, the automatic adjustment member is engaged with the low pressure output end through the magnetic connector.
9. The apparatus of claim 1, wherein the automatic liquid stopper comprises a liquid inlet chamber and a liquid outlet chamber, and a liquid stopper film with at least two apertures is disposed between the liquid inlet chamber and the liquid outlet chamber.
10. A device for infusing chemotherapeutic agents as claimed in claim 9, wherein said automatic infusion device is provided with a control member for adjustably controlling the passage of the liquid drug through one, two or more of said infusion membranes.
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| CN202110792856.7A CN113368337B (en) | 2021-07-14 | 2021-07-14 | Device for delivering chemotherapeutic drugs |
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