CN113353873B - Quick aseptic partial shipment device of bacterin semi-manufactured goods - Google Patents

Quick aseptic partial shipment device of bacterin semi-manufactured goods Download PDF

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Publication number
CN113353873B
CN113353873B CN202110114592.XA CN202110114592A CN113353873B CN 113353873 B CN113353873 B CN 113353873B CN 202110114592 A CN202110114592 A CN 202110114592A CN 113353873 B CN113353873 B CN 113353873B
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tank
subpackaging
vaccine
unit
disinfection
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CN113353873A (en
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王倩
杨孝延
刘国东
钱立生
韩伟丽
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Anhui University of Science and Technology
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Anhui University of Science and Technology
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67CCLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C7/00Concurrent cleaning, filling, and closing of bottles; Processes or devices for at least two of these operations
    • B67C7/0073Sterilising, aseptic filling and closing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67CCLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C3/00Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
    • B67C3/02Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
    • B67C3/22Details
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67CCLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C3/00Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
    • B67C3/02Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
    • B67C3/22Details
    • B67C3/26Filling-heads; Means for engaging filling-heads with bottle necks

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  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

The invention relates to the technical field of vaccine production, in particular to a quick aseptic subpackaging device for a vaccine semi-finished product, which comprises a rack, a liquid storage tank, a sterilizing unit, a subpackaging unit, a bottle conveying unit and a controller for controlling the work of the aseptic subpackaging device, wherein the rack is used for accommodating a vaccine to be packaged; the liquid storage tank is arranged on the rack, the liquid storage tank is communicated with the disinfection unit through a liquid conveying pipe, and an infusion pump is arranged on the liquid conveying pipe and is used for pumping the vaccine in the liquid storage tank into the disinfection unit; through setting up the disinfection jar, ultraviolet lamp, pivot and roof, it is rotatory that rotary mechanism drives the roof through the pivot, the transfer line spouts the bacterin on the roof, rotatory roof is got rid of the bacterin through centrifugal force on the inner wall of disinfection jar, make the bacterin slide down along the inner wall of disinfection jar, the ultraviolet lamp of rotating condition this moment can disinfect to the bacterin on the disinfection jar inner wall by the efficient, the bacterin after the disinfection falls into the partial shipment unit after, empty medicine on the delivery bottle unit is filled.

Description

Quick aseptic partial shipment device of bacterin semi-manufactured goods
Technical Field
The invention relates to the technical field of vaccine production, in particular to a quick aseptic subpackaging device for semi-finished vaccine products.
Background
The vaccine is an automatic immune preparation for preventing infectious diseases, which is prepared by artificially attenuating, inactivating or utilizing transgenosis methods for pathogenic microorganisms (such as bacteria, rickettsia, viruses and the like) and metabolites thereof. The vaccine retains the property of pathogenic bacteria to stimulate the immune system of an animal. The production of vaccines generally comprises the steps of preparing a vaccine semi-finished product solution, subpackaging the solution into packaging bottles, and then carrying out freeze-drying to obtain a vaccine finished product. The split charging device for the vaccine semi-finished products mostly conveys the vaccine semi-finished product solution to the split charging head during split charging, then presses the vaccine semi-finished product solution into a packaging bottle through a piston in the cylinder split charging head, and although the split charging of the vaccine semi-finished product solution can be realized, the problem of inaccurate metering exists. In addition, the dispensing head used on the existing dispensing device is a syringe type dispensing head which is in a hollow conical shape and consists of a dispensing head entity and an inner cylinder of the dispensing head, and the upper part and the lower part of the dispensing head are provided with openings.
A chinese patent with patent application number 2019204089332 discloses a quick aseptic subpackaging device for vaccine semi-finished products, which comprises a subpackaging and sterilizing device and a controller. Partial shipment degassing unit includes the frame, be equipped with the ultraviolet germicidal lamp in the frame, the ultraviolet germicidal lamp spirals outward and is equipped with the sterilization pipeline, the sterilization pipeline lower extreme all is connected with the drain pipe, the drain pipe stretches out the frame, be equipped with flowmeter and solenoid valve on the drain pipe, flowmeter and solenoid valve are connected with the controller electricity respectively, the frame outer joint has the storage tank that is used for supplying bacterin semi-manufactured goods solution, drain pipe exit sliding connection has the leak protection pipe, the leak protection pipe includes outer entity and cavity pipeline, the cavity pipeline is for leaking hopper-shaped, be connected with on the leak protection pipe and be used for driving the leak protection pipe for the gliding mobile device from top to bottom of drain pipe.
According to the technical scheme, the vaccine semi-finished products can be subpackaged, but the technical scheme has the following defects: 1. when the ultraviolet lamp irradiates the sterilizing pipeline, the sterilizing effect on the vaccine in the sterilizing pipeline is poor; 2. during subpackaging, air bubbles are generated in the vaccine, and the technical scheme cannot extract the air bubbles in the vaccine, so that the subpackaging amount of the vaccine in a medicine bottle is reduced, and the later inoculation effect is influenced; 3. in this partial shipment in-process, when stopping the canning, because bacterin semi-manufactured goods solution viscosity is less, cause the overhead remaining bacterin semi-manufactured goods solution of partial shipment to slide down from the partial shipment overhead, on the drip leaks the workstation, cause the waste of bacterin semi-manufactured goods solution, cause the pollution more easily.
Disclosure of Invention
The invention aims to provide a quick aseptic subpackaging device for semi-finished vaccine products, and aims to solve the problems in the prior art.
The invention is realized by the following steps:
a quick sterile subpackaging device for vaccine semi-finished products comprises a rack, a liquid storage tank, a sterilizing unit, a subpackaging unit, a bottle conveying unit and a controller for controlling the work of the sterile subpackaging device; wherein the content of the first and second substances,
the liquid storage tank is arranged on the rack, the liquid storage tank is communicated with the disinfection unit through a liquid conveying pipe, and an infusion pump is arranged on the liquid conveying pipe and is used for pumping the vaccine in the liquid storage tank into the disinfection unit;
the disinfection unit comprises a disinfection tank, an ultraviolet lamp, a rotating shaft and a top plate, wherein the disinfection tank is of a hollow structure with an opening at the lower end, a liquid conveying pipe penetrates through the center of the top wall of the disinfection tank, a water outlet of the liquid conveying pipe is arranged inside the disinfection tank, the top plate is arranged right below the water outlet of the liquid conveying pipe, the upper side surface of the top plate is of a conical structure, the rotating shaft is fixedly connected with the center of the lower side of the top plate, the lower end of the rotating shaft is connected with a rotating mechanism, the rotating mechanism is used for driving the rotating shaft to rotate, the ultraviolet lamp is fixedly mounted on the side wall of the rotating shaft, and the ultraviolet lamp is electrically connected with a controller;
the split charging unit is communicated with the lower part of the sterilizing tank and is used for receiving the vaccine flowing down from the sterilizing tank and split charging the vaccine into medicine bottles;
the bottle conveying unit is arranged below the sub-packaging unit and is used for conveying medicine bottles to the lower side of the sub-packaging unit.
Further, the partial shipment unit is including dividing tinning, mounting panel, branch tubulation, flowmeter and solenoid valve, the jar mouth of branch tinning rotates between the jar mouth of jar mouth and disinfection jar to be connected, and the fixed interlude has the pivot on the tank bottoms of branch tinning, the pivot is used for driving the partial shipment jar rotatory, and a plurality of mounting panels of fixedly connected with on the outer wall of branch tinning, the one end intercommunication of branch tubulation is on dividing the tinning, and the vertical setting of the other end of branch tubulation is provided with flowmeter and solenoid valve on the branch tubulation on the mounting panel.
Further, the solenoid valve includes casing, case, connecting rod, piston, iron plate, electro-magnet, No. two electro-magnets and pipette, the branch tubulation is connected to the both sides of casing, and case sliding connection has case and piston at the inner wall sliding connection of casing, through connecting rod fixed connection between case and piston, the middle part fixedly connected with iron plate of connecting rod, electro-magnet and No. two electro-magnets of fixedly connected with on the inner wall of casing, electro-magnet and No. two electro-magnets set up respectively in the upper and lower both sides of iron plate, and the intercommunication has the one end of pipette on the diapire of casing, and the other end intercommunication of pipette is on the branch tubulation, and electro-magnet and No. two electro-magnets all with controller electric connection.
Further, it includes inner rotating disc and spacing ring to send a bottle unit, set up a plurality of recesses that correspond with the medicine appearance on the outer edge of inner rotating disc, the position setting of recess is under the branch dress pipe, the fixed cup joint of inner rotating disc is in the pivot, the spacing ring cup joints the periphery at the inner rotating disc, has seted up feed inlet and discharge gate on the spacing ring.
Furthermore, a threaded water tank is arranged on the inner wall of the disinfection tank and used for drainage of the vaccine.
Further, be provided with agitating unit in the liquid storage pot, agitating unit is used for stirring the bacterin in the liquid storage pot.
Further, rotary mechanism includes step motor and bevel gear, step motor's output shaft passes through the transmission connection pivot between the bevel gear, step motor and controller electric connection.
Further, the shape of the split charging tank is a cone with the diameter of the bottom larger than that of the top.
Compared with the prior art, the quick sterile subpackaging device for the vaccine semi-finished product provided by the invention has the following advantages:
1. through setting up the disinfection jar, ultraviolet lamp, pivot and roof, it is rotatory that rotary mechanism drives the roof through the pivot, the transfer line spouts the bacterin on the roof, rotatory roof is got rid of the bacterin through centrifugal force on the inner wall of disinfection jar, make the bacterin slide down along the inner wall of disinfection jar, the ultraviolet lamp of rotating condition this moment can disinfect to the bacterin on the disinfection jar inner wall by the efficient, the bacterin after the disinfection falls into the partial shipment unit after, empty medicine on the delivery bottle unit is filled.
2. By arranging the split charging tank, the mounting plate, the split charging pipe, the flowmeter and the electromagnetic valve, the amount of the vaccine solution to be split charged into a single medicine bottle is input into the controller, then the controller controls the bottle-feeding unit to work, the vaccine in the subpackaging tank is extruded into the subpackaging pipe through centrifugal force and enters the medicine bottle through the subpackaging pipe, the flow meter measures the flow, when the flow reaches a set value, the controller controls the electromagnetic valve to close, when the subpackaged medicine bottles reach the discharge hole, the materials are discharged from the discharge hole, the feeding and the sub-packaging can be continuously carried out, when the sub-packaging amount is changed, new set values can be input into the controller again, so that the requirements of different dispensing quantities can be met, the rotating dispensing cans can drive the vaccine inside to rotate, because the density of the vaccine is greater than that of the air bubbles, the air bubbles in the vaccine can be extruded out of the vaccine, and the condition that the subpackage amount is inaccurate due to the existence of the air bubbles in the vaccine is eliminated.
3. Through setting up the casing, the case, the connecting rod, the piston isotructure, when the solenoid valve was opened, an electro-magnet outage, No. two electro-magnets circular telegrams, No. two electro-magnets adsorb the iron plate, make case intercommunication partial shipment pipe, the piston extrusion is in the bottom of casing simultaneously, the partial shipment is carried out this moment, after the partial shipment is accomplished, an electro-magnet circular telegram, No. two electro-magnet outage, an electro-magnet adsorbs the iron plate this moment, make the case plug up the partial shipment pipe, the piston upwards moves simultaneously, with the intraductal bacterin suction of partial shipment to imbibition intraductal, therefore the hourglass can not take place for bacterin semi-manufactured goods solution.
4. Through set up the screw thread basin on the inner wall at the disinfection jar, the screw thread basin is used for the drainage effect of bacterin, is got rid of the bacterin that can follow the spiral of screw thread basin and flows down by the roof on the disinfection jar inner wall, can increase the length of time of bacterin whereabouts to further improve the effect of sterilization.
5. Through be provided with agitating unit in the liquid storage pot, can improve the mixing degree of bacterin, guarantee the even degree of bacterin.
6. Through adopting the partial shipment jar that the shape is the cone that the bottom diameter is greater than the top diameter, the centrifugal force that the bottom produced is greater than the centrifugal force that the top produced during rotation, and the bacterin of bottom forms ascending swirl under the effect of external force, can avoid the deposit of frame inner chamber bottom bacterin, guarantees the homogeneity of partial shipment bacterin.
Drawings
FIG. 1 is a schematic structural diagram of a rapid sterile packaging device for vaccine semi-finished products provided by the present invention;
FIG. 2 is a schematic view of the internal structure of the sterilization unit provided by the present invention;
FIG. 3 is a schematic diagram of the internal structure of the dispensing unit provided by the present invention;
FIG. 4 is a top plan view of a bottle feeding unit provided by the present invention;
FIG. 5 is a schematic view of the internal structure of the solenoid valve provided by the present invention in an open state;
fig. 6 is a schematic view of the internal structure of the solenoid valve provided by the present invention in a closed state.
In the figure: the device comprises a rack 1, a liquid storage tank 2, a disinfection unit 3, a disinfection tank 31, an ultraviolet lamp 32, a rotating shaft 33, a top plate 34, a rotating mechanism 35, a threaded water tank 36, a dispensing unit 4, a dispensing tank 41, a mounting plate 42, a dispensing pipe 43, a flow meter 44, an electromagnetic valve 45, a shell 451, a valve core 452, a connecting rod 453, a piston 454, an iron block 455, a first electromagnet 456, a second electromagnet 457, a pipette 458, a bottle conveying unit 5, an inner rotary disc 51, a limiting ring 52, a medicine 53, a feeding hole 54, a discharging hole 55, a transfusion tube 6, a transfusion pump 7 and a stirring device 8.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in further detail with reference to fig. 1 to 6 and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The following describes the implementation of the present invention in detail with reference to the preferred embodiments.
The embodiment provides a quick sterile subpackaging device for vaccine semi-finished products, which comprises a rack 1, a liquid storage tank 2, a sterilizing unit 3, a subpackaging unit 4, a bottle conveying unit 5 and a controller for controlling the work of the sterile subpackaging device, as shown in fig. 1; wherein the content of the first and second substances,
the liquid storage tank 2 is arranged on the rack 1, the liquid storage tank 2 is communicated with the disinfection unit 3 through a liquid conveying pipe 6, an liquid conveying pump 7 is arranged on the liquid conveying pipe 6, and the liquid conveying pump 7 is used for pumping the vaccine in the liquid storage tank 2 into the disinfection unit 3;
as shown in fig. 2, the sterilizing unit 3 includes a sterilizing tank 31, an ultraviolet lamp 32, a rotating shaft 33 and a top plate 34, the sterilizing tank 31 is of a hollow structure with an opening at the lower end, a liquid conveying pipe 6 penetrates through the center of the top wall of the sterilizing tank 31, a water outlet of the liquid conveying pipe 6 is arranged inside the sterilizing tank 31, the top plate 34 is arranged right below the water outlet of the liquid conveying pipe 6, the upper side surface of the top plate 34 is of a conical structure, the rotating shaft 33 is fixedly connected to the center of the lower side of the top plate 34, the lower end of the rotating shaft 33 is connected with a rotating mechanism 35, the rotating mechanism 35 is used for driving the rotating shaft 33 to rotate, the ultraviolet lamp 32 is fixedly installed on the side wall of the rotating shaft 33, and the ultraviolet lamp 32 is electrically connected with a controller;
the split charging unit 4 is communicated below the sterilizing tank 31, and the split charging unit 4 is used for receiving the vaccine flowing down from the sterilizing tank 31 and split charging the vaccine into medicine bottles;
the bottle feeding unit 5 is disposed below the dispensing unit 4, and the bottle feeding unit 5 is configured to feed a medicine bottle below the dispensing unit 4.
The during operation, the transfer pump 7 passes through transfer line 6 suction with the bacterin in the liquid storage pot 2 to the disinfection jar 31 in, controller control ultraviolet lamp 32 and rotary mechanism 35 work, because ultraviolet lamp 32 is relative pivoted state with the controller, consequently, can pass through the mode electric connection of carbon brush between controller and ultraviolet lamp 32, rotary mechanism 35 drives roof 34 rotatory through pivot 33, transfer line 6 spouts the bacterin to roof 34 on, rotatory roof 34 is thrown to the inner wall of disinfection jar 31 with the bacterin through centrifugal force on, make the bacterin slide down along the inner wall of disinfection jar 31, the ultraviolet lamp 32 of rotating condition can the efficient disinfect to the bacterin on the disinfection jar 31 inner wall this moment, the bacterin after the disinfection falls into partial shipment unit 4 back, empty medicine 53 to sending on the bottle unit 5 is filled.
As shown in fig. 3, in this embodiment, the dispensing unit 4 includes a dispensing tank 41, a mounting plate 42, a dispensing tube 43, a flow meter 44, and a solenoid valve 45, the opening of the dispensing tank 41 is rotatably connected to the opening of the sterilizing tank 31, a rotary seal ring is used to seal the rotation joint, a rotating shaft 33 is fixedly inserted into the bottom of the dispensing tank 41, the rotating shaft 33 is used to drive the dispensing tank 41 to rotate, the mounting plates 42 are fixedly connected to the outer wall of the dispensing tank 41, one end of the dispensing tube 43 is communicated with the dispensing tank 41, the other end of the dispensing tube 43 is vertically arranged on the mounting plate 42, and the dispensing tube 43 is provided with the flow meter 44 and the solenoid valve 45;
as shown in fig. 4, the bottle feeding unit 5 includes an inner rotary disc 51 and a limiting ring 52, a plurality of grooves corresponding to the shape of the medicine 53 are formed on an outer edge of the inner rotary disc 51, the grooves are disposed right below the dispensing tube 43, the inner rotary disc 51 is fixedly sleeved on the rotating shaft 33, the limiting ring 52 is sleeved on the periphery of the inner rotary disc 51, and a feeding port 54 and a discharging port 55 are formed on the limiting ring 52.
When the automatic vaccine packaging machine works, the amount of vaccine solution required to be packaged in a single medicine bottle is input into the controller, then the controller controls the bottle conveying unit 5 to work, the empty medicine bottle is moved into the groove of the inner rotary disc 51 from the feeding hole 54, the electromagnetic valve 45 is opened at the moment, the vaccine in the packaging tank 41 is extruded into the packaging pipe 43 through centrifugal force and enters the medicine bottle through the packaging pipe 43, the flow meter 44 measures the flow, when the flow reaches a set value, the controller controls the electromagnetic valve 45 to be closed, the packaged medicine bottle is discharged from the discharging hole 55 after reaching the discharging hole 55, feeding and packaging can be continuously carried out, when the packaging amount changes, a new set value can be input into the controller again, therefore, the requirements of different packaging amounts can be met, the rotating packaging tank 41 can drive the vaccine in the inner part to rotate, and because the density of the vaccine is greater than that of bubbles, the bubbles in the vaccine can be extruded from the vaccine, thereby eliminating the condition of inaccurate subpackage amount caused by the existence of air bubbles in the vaccine.
As shown in fig. 5-6, in this embodiment, the electromagnetic valve 45 includes a housing 451, a valve core 452, a connecting rod 453, a piston 454, an iron block 455, a first electromagnet 456, a second electromagnet 457, and a pipette 458, where two sides of the housing 451 are connected to the dispensing tube 43, the valve core 452 is slidably connected to an inner wall of the housing 451 and slidably connected to the valve core 452 and the piston 454, the valve core 452 and the piston 454 are fixedly connected through the connecting rod 453, the iron block 455 is fixedly connected to a middle portion of the connecting rod 453, the first electromagnet 456 and the second electromagnet 457 are fixedly connected to an inner wall of the housing 451, the first electromagnet 456 and the second electromagnet 457 are respectively disposed on upper and lower sides of the iron block 455, one end of the pipette 458 is communicated to a bottom wall of the housing 451, the other end of the pipette 458 is communicated to the dispensing tube 43, and both the first electromagnet 456 and the second electromagnet 457 are electrically connected to the controller; when the solenoid valve 45 is opened, No. one electro-magnet 456 outage, No. two electro-magnet 457 circular telegram, No. two electro-magnet 457 adsorbs iron plate 455 for case 452 communicates branch dress pipe 43, piston 454 extrusion is in the bottom of casing 451 simultaneously, carry out the partial shipment this moment, after the partial shipment is accomplished, No. one electro-magnet 456 circular telegram, No. two electro-magnet 457 circular telegram, No. one electro-magnet 456 adsorbs iron plate 455 this moment, make case 452 block up branch dress pipe 43, piston 454 upwards moves simultaneously, with the bacterin suction in the branch dress pipe 43 in the pipette 458, consequently, the drippage can not take place for bacterin semi-manufactured product solution.
In this embodiment, threaded water tank 36 has been seted up on the inner wall of disinfection jar 31, threaded water tank 36 is used for the drainage effect of bacterin, and the bacterin that is got rid of on the inner wall of disinfection jar 31 by roof 34 can be along the spiral flow down of threaded water tank 36, can increase the length of time of bacterin whereabouts to further improve the effect of sterilization.
In this embodiment, be provided with agitating unit 8 in the liquid storage pot 2, agitating unit 8 is used for stirring the bacterin in the liquid storage pot 2, can improve the mixing degree of bacterin, guarantees the even degree of bacterin.
In this embodiment, the rotating mechanism 35 includes a stepping motor and a bevel gear, an output shaft of the stepping motor is connected to the rotating shaft 33 through transmission between the bevel gears, and the stepping motor is electrically connected to the controller.
In this embodiment, the shape of partial shipment jar 41 is the cone that the bottom diameter is greater than the top diameter, and the centrifugal force that the bottom produced is greater than the centrifugal force that the top produced during rotation, and the bacterin of bottom forms ascending swirl under the effect of external force, can avoid the deposit of frame inner chamber bottom bacterin, guarantees the homogeneity of partial shipment bacterin.
The same or similar reference numerals in the drawings of the present embodiment correspond to the same or similar components; in the description of the present invention, it should be understood that if there is an orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", etc. based on the orientation or positional relationship shown in the drawings, it is only for convenience of describing the present invention and simplifying the description, but it is not intended to indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and are not to be construed as limiting the present patent, and the specific meaning of the terms may be understood by those skilled in the art according to specific circumstances.
Referring to the drawings, there is shown a preferred embodiment of the present invention.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.

Claims (8)

1. A quick aseptic subpackaging device for semi-finished vaccine is characterized by comprising a rack (1), a liquid storage tank (2), a sterilizing unit (3), a subpackaging unit (4), a bottle conveying unit (5) and a controller for controlling the work of the aseptic subpackaging device; wherein the content of the first and second substances,
the liquid storage tank (2) is arranged on the rack (1), the liquid storage tank (2) is communicated with the disinfection unit (3) through a liquid conveying pipe (6), an liquid conveying pump (7) is arranged on the liquid conveying pipe (6), and the liquid conveying pump (7) is used for pumping the vaccine in the liquid storage tank (2) into the disinfection unit (3);
the disinfection unit (3) comprises a disinfection tank (31), an ultraviolet lamp (32), a rotating shaft (33) and a top plate (34), wherein the disinfection tank (31) is of a hollow structure with an open lower end, a liquid conveying pipe (6) penetrates through the center of the top wall of the disinfection tank (31), a water outlet of the liquid conveying pipe (6) is formed in the disinfection tank (31), the top plate (34) is arranged under the water outlet of the liquid conveying pipe (6), the upper side surface of the top plate (34) is of a conical structure, the rotating shaft (33) is fixedly connected with the center of the lower side of the top plate (34), the lower end of the rotating shaft (33) is connected with a rotating mechanism (35), the rotating mechanism (35) is used for driving the rotating shaft (33) to rotate, the ultraviolet lamp (32) is fixedly mounted on the side wall of the rotating shaft (33), and the ultraviolet lamp (32) is electrically connected with a controller;
the split charging unit (4) is communicated below the sterilizing tank (31), and the split charging unit (4) is used for receiving the vaccine flowing down from the sterilizing tank (31) and split charging the vaccine into medicine bottles;
the bottle conveying unit (5) is arranged below the sub-packaging unit (4), and the bottle conveying unit (5) is used for conveying medicine bottles to the lower portion of the sub-packaging unit (4).
2. The quick aseptic subpackaging device for the vaccine semi-finished products according to claim 1, wherein the subpackaging unit (4) comprises a subpackaging tank (41), a mounting plate (42), a subpackaging pipe (43), a flow meter (44) and a solenoid valve (45), the tank opening of the subpackaging tank (41) is rotatably connected with the tank opening of the sterilizing tank (31), a rotating shaft (33) is fixedly inserted on the tank bottom of the subpackaging tank (41), the rotating shaft (33) is used for driving the subpackaging tank (41) to rotate, a plurality of mounting plates (42) are fixedly connected on the outer wall of the subpackaging tank (41), one end of the subpackaging pipe (43) is communicated with the subpackaging tank (41), the other end of the subpackaging pipe (43) is vertically arranged on the mounting plate (42), and the subpackaging pipe (43) is provided with the flow meter (44) and the solenoid valve (45).
3. The quick sterile subpackaging device for the vaccine semi-finished products according to claim 2, characterized in that the electromagnetic valve (45) comprises a housing (451), a valve core (452), a connecting rod (453), a piston (454), an iron block (455), a first electromagnet (456), a second electromagnet (457) and a pipette (458), the subpackaging tube (43) is connected to both sides of the housing (451), the valve core (452) and the piston (454) are connected to the inner wall of the housing (451) in a sliding manner, the valve core (452) and the piston (454) are fixedly connected through the connecting rod (453), the iron block (455) is fixedly connected to the middle of the connecting rod (453), the first electromagnet (456) and the second electromagnet (457) are fixedly connected to the inner wall of the housing (451), the first electromagnet (456) and the second electromagnet (457) are respectively arranged on the upper and lower sides of the iron block (455), and one end of the pipette (458) is communicated to the bottom wall of the housing (451), the other end of the pipette (458) is communicated with the split charging pipe (43), and the first electromagnet (456) and the second electromagnet (457) are both electrically connected with the controller.
4. The quick sterile subpackaging device for the vaccine semi-finished products according to claim 2, wherein the bottle feeding unit (5) comprises an inner rotary disk (51) and a limiting ring (52), the outer edge of the inner rotary disk (51) is provided with a plurality of grooves corresponding to the shapes of the medicines (53), the grooves are arranged right below the subpackaging pipe (43), the inner rotary disk (51) is fixedly sleeved on the rotating shaft (33), the limiting ring (52) is sleeved on the periphery of the inner rotary disk (51), and the limiting ring (52) is provided with a feeding hole (54) and a discharging hole (55).
5. The quick aseptic subpackaging device for the vaccine semi-finished products according to claim 1, wherein a threaded water tank (36) is formed on the inner wall of the sterilizing tank (31), and the threaded water tank (36) is used for drainage of the vaccine.
6. A rapid aseptic dispensing device for vaccine semifinished products according to claim 1, wherein a stirring device (8) is provided in said liquid storage tank (2), said stirring device (8) being adapted to stir the vaccine in the liquid storage tank (2).
7. The quick sterile subpackaging device for vaccine semi-finished products according to claim 4, wherein the rotating mechanism (35) comprises a stepping motor and bevel gears, an output shaft of the stepping motor is connected with the rotating shaft (33) through transmission between the bevel gears, and the stepping motor is electrically connected with the controller.
8. A rapid aseptic dispensing device of vaccine intermediates according to claim 3, wherein said dispensing canister (41) is in the form of a cone with a bottom diameter greater than a top diameter.
CN202110114592.XA 2021-01-26 2021-01-26 Quick aseptic partial shipment device of bacterin semi-manufactured goods Active CN113353873B (en)

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