CN113318344B - Pulsating centrifugal blood pump - Google Patents
Pulsating centrifugal blood pump Download PDFInfo
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- CN113318344B CN113318344B CN202110335111.8A CN202110335111A CN113318344B CN 113318344 B CN113318344 B CN 113318344B CN 202110335111 A CN202110335111 A CN 202110335111A CN 113318344 B CN113318344 B CN 113318344B
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Abstract
The invention provides a pulsating centrifugal blood pump applied to the assistance of artificial hearts and ventricles. The blood pump mainly comprises a blood pump system and a pulsation system, wherein the blood pump system consists of a pump shell, a base, a corrugated pipe, an impeller and a main shaft and is used for maintaining blood circulation, the pulsation system consists of the pump shell, the corrugated pipe, the base, a connecting rod and the main shaft and is used for periodically changing the volume of a pump cavity to realize blood pressure pulsation, and the blood pump system and the pulsation system work in a coupling mode. The invention has the advantages of simple structure, small volume, implantation and accordance with the physiological characteristics of human body.
Description
Technical Field
The invention relates to the technical field of centrifugal pumps, in particular to a pulsating centrifugal blood pump.
Background
Cardiovascular disease causes unmortal damage to human health, the end result of which is heart failure, taking away the patient's life. The most effective means of treating and even curing severe cardiovascular disease is to perform heart transplantation, but many patients die indefinitely while waiting for a cardiac source due to the difficulty in accurately matching the patient to the heart provider's heart and the always much higher amount of cardiac recipients than the cardiac donor. The heart, one of the most critical organs of human, if only relying on natural heart transplantation, will be far from meeting the demand of patients for donors, so finding a new suitable reliable heart source, alleviating the suffering of patients with heart diseases becomes an important research direction in the medical field of science, and artificial heart and ventricular assist are brought to bear.
Artificial heart and ventricular assist generally comprises four major parts, a blood pump, a monitoring system, a drive device and an energy supply device, wherein the blood pump is the most central component. Artificial heart and ventricular assist have experienced a long developmental history from the advent to the present. The first generation artificial heart and ventricular assist blood pumps were pneumatic positive displacement, were biomimetic pulsatile, but were large and poorly implantable. The second generation artificial heart and ventricle auxiliary blood pump is a rotary blade type, including centrifugal type, axial flow type and mixed flow type, and has small volume and good implantation property. It produces continuous stable blood pressure without pulsatility. In addition, because it uses mechanical bearings to support the rotor, the blood is destroyed by frictional heating to cause hemolysis and thrombosis, and sealing measures are required. The third generation artificial heart and ventricle auxiliary blood pump is still of a rotary blade type, but a magnetic suspension or liquid suspension bearing is adopted, so that the occurrence probability of hemolysis and thrombus is effectively reduced.
The human natural heart is beating, and in one cardiac cycle, systolic and diastolic pressures are generated as a result of the contraction and relaxation of the ventricles. Whether a blood pump needs to pulsate to conform to the natural physiological characteristics of the human body has been a topic of considerable discussion. Some scholars believe that the pulsatile blood pump can improve microcirculation, promote metabolism, and improve perfusion and functions of important organs such as kidney, brain, liver, heart and the like. The non-pulsatile blood pump outputs continuous fluid, the flow rate is low, the pressure is low, the non-pulsatile blood pump has no negative pressure period, the resistance of peripheral blood vessels is increased along with the prolonging of time, capillary vessels are closed, the microcirculation is poor in perfusion, metabolic acidosis is easy to generate, tissue edema and important organ dysfunction are caused. Others believe that in many respects, beat flow is not significantly different from non-beat flow, and have associated example subsidies. Therefore, at present, the pulsatile flow must be the best, and whether the non-pulsatile flow has a hidden trouble is questionable.
Based on the technical background, the pulsating centrifugal blood pump has the advantages of small volume and easiness in implantation, and also has pulsation to accord with the physiological characteristics of a human body.
Disclosure of Invention
The invention provides a pulsating centrifugal blood pump applied to artificial heart and ventricle assistance, which is characterized by comprising a blood pump system and a pulsating system which work in a coupling way; the blood pump system comprises a pump shell (2), a base (8), a corrugated pipe (6), an impeller (18) and a main shaft (11); the pulsation system comprises a pump shell (2), a corrugated pipe (6), a base (8), a connecting rod (9) and a main shaft (11); the pump shell (2) is provided with 2 groups of pump shell platforms (4) and pump shell cylinders (5) which are symmetrically distributed on the circumference of the pump shell relative to the pump shell inlet (1), and the pump shell platforms (4) and the pump shell cylinders (5) are in one-to-one correspondence; the base (8) is provided with a base center hole (17), 2 groups of base platforms (14) and base platform holes (15) which are symmetrically distributed on the circumference relative to the base center hole (17), the base platforms (14) and the base platform holes (15) are in one-to-one correspondence, and a base rectangular hole (16) is formed below each base platform (14); the impeller (18) is provided with an impeller center hole (19), a plurality of impeller blades (20) are uniformly distributed in the circumferential direction, and the impeller blades (20) are spiral flow channels; the connecting rod (9) is provided with a connecting rod pump shell hole (12) and a connecting rod base hole (13), and the connecting rod (9) is in a broken line type or an arc line type; the main shaft (11) is provided with a main shaft groove-shaped lug (10), the section of the main shaft groove-shaped lug (10) is rectangular or double-round-head groove-shaped, and the main shaft groove-shaped lug (10) is centrosymmetric about the main shaft (11).
The blood pump system has the following connection modes of all parts: the bottom surface of the pump shell (2) is fixedly connected with a cylindrical corrugated pipe (6), the other surface of the corrugated pipe (6) is fixedly connected with the base (8), the pump shell (2), the corrugated pipe (6) and the base (8) form a closed pump cavity, and the main shaft (11) penetrates through a central hole (19) of the impeller and is fixedly connected with the impeller (18).
The connection mode of each component of the pulse system is as follows: the connecting rod (9) penetrates through a base rectangular hole (16) of the base (8), is sleeved on a pump shell cylinder (5) of the pump shell (2) through a connecting rod pump shell hole (12), is not fixedly connected and can rotate relatively; the bolt (7) passes through a base platform hole (15) of the base (8) and a connecting rod base hole (13) of the connecting rod (9), and the connecting rod (9) and the base (8) are connected, are not fixedly connected and can rotate relatively.
The structure parameter relationship of the pulse system is as follows: the length of the main shaft groove-shaped convex block (10) is l1The length of the minimum radial distance between the connecting rod (9) and the main shaft (11) is l2The axial distance between the base (8) and the groove-shaped projection (10) of the main shaft is l3The maximum axial distance between the base (8) and the pump shell cylinder (5) is l4The maximum contraction of the length of the corrugated pipe is delta lmaxThey satisfy the following formula:
the working process of the device is as follows: in the embodiment, a main shaft (11) is driven by a motor, the main shaft (11) rotates to drive a impeller (18) to synchronously rotate, meanwhile, a main shaft groove-shaped lug (10) of the main shaft (11) rotates to periodically poke a connecting rod (9), the connecting rod (9) periodically pulls a pump shell (2), and the pump shell (2) periodically compresses a corrugated pipe (6) to realize the periodic change of the volume of a pump cavity. Blood flows into the blood pump from the pump shell inlet (1), works and pressurizes through the impeller (18), and flows out from the pump shell outlet (3) due to centrifugal force. In the process, the force for restoring the connecting rod (9) to the original position comes from the elastic force of the corrugated pipe (6). As the main shaft groove-shaped lug (10) is symmetrical about the center of the main shaft (11), the reaction force of the main shaft groove-shaped lug (10) received by the connecting rod (9) is also symmetrical about the center of the main shaft (11), and the main shaft (11) cannot be subjected to unbalanced force during high-speed rotation, so that the vibration stability is good.
The beating principle of the device of the invention is as follows: the main shaft groove-shaped convex blocks (10) of the main shaft (11) rotate to periodically stir the connecting rods (9), the connecting rods (9) periodically pull the pump shell (2), and the pump shell (2) periodically compresses the corrugated pipes (6) to realize the periodic change of the volume of the pump cavity. When the pump chamber volume is maximum, the pressure increasing ratio of the impeller (18) is minimum, and the blood pressure flowing out of the pump shell outlet (3) is lowest and is diastolic pressure. When the pump chamber volume is minimum, the pressure ratio of the impeller (18) is maximum, and the blood pressure flowing out from the pump shell outlet (3) is highest and is contraction pressure. The duration of the pump chamber volume from maximum to minimum to maximum is the cardiac cycle. The size and the amplitude of the pulsating blood pressure can be adjusted by adjusting the length and the elastic coefficient of the corrugated pipe (6). The frequency of the pulsating blood pressure can be adjusted by adjusting the rotation speed of the main shaft (11). In the process, the force for restoring the connecting rod (9) to the original position comes from the elastic force of the corrugated pipe (6). As the main shaft groove-shaped lug (10) is symmetrical about the center of the main shaft (11), the reaction force of the main shaft groove-shaped lug (10) received by the connecting rod (9) is also symmetrical about the center of the main shaft (11), and the main shaft (11) cannot be subjected to unbalanced force during high-speed rotation, so that the vibration stability is good. The application scene of the beating mechanism of the device is not limited to artificial heart and ventricular assist, and the device can be applied to or slightly changed on the basis of the invention in the mechanical field of centrifugal impellers such as centrifugal compressors, centrifugal pumps, centrifugal fans, centripetal turbines and centripetal water turbines which need to provide pulsating pressure.
Drawings
Fig. 1 is a schematic diagram of the general structure of a pulsating centrifugal blood pump of the present invention.
Fig. 2 is an isometric illustration of the spindle of a pulsatile centrifugal blood pump of the present invention.
Fig. 3 is an isometric illustration of the linkage of a pulsatile centrifugal blood pump of the present invention.
Figure 4 is an isometric illustration of the base of a pulsatile centrifugal blood pump of the present invention.
Fig. 5 is a schematic elevational view of the impeller of a pulsatile centrifugal blood pump of the present invention.
Fig. 6 is an isometric illustration of the pump housing of a pulsatile centrifugal blood pump of the present invention.
Fig. 7 is a schematic diagram of some of the structural parameters of a pulsatile centrifugal blood pump of the present invention.
Detailed Description
The following detailed description of embodiments of the present invention is provided in connection with the accompanying drawings and examples. The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.
The working process of the pulsating centrifugal blood pump is as follows: the main shaft (11) is driven by a motor, the main shaft (11) rotates to drive the impeller (18) to synchronously rotate, meanwhile, the main shaft groove-shaped convex block (10) of the main shaft (11) rotates to periodically stir the connecting rod (9), the connecting rod (9) periodically pulls the pump shell (2), and the pump shell (2) periodically compresses the corrugated pipe (6) to realize the periodic change of the volume of the pump cavity. Blood flows into the blood pump from the pump shell inlet (1), works and pressurizes through the impeller (18), and flows out from the pump shell outlet (3) due to centrifugal force.
The pulsation principle of the pulsation type centrifugal blood pump provided by the invention is as follows: the main shaft groove-shaped convex blocks (10) of the main shaft (11) rotate to periodically stir the connecting rods (9), the connecting rods (9) periodically pull the pump shell (2), and the pump shell (2) periodically compresses the corrugated pipes (6) to realize the periodic change of the volume of the pump cavity. When the pump chamber volume is maximum, the pressure increase ratio of the impeller (18) is minimum, and the blood pressure flowing out of the pump case outlet (3) is lowest and is diastolic pressure. When the pump chamber volume is minimum, the pressure ratio of the impeller (18) is maximum, and the blood pressure flowing out from the pump shell outlet (3) is highest and is contraction pressure. The duration of the pump chamber volume from maximum to minimum to maximum is the cardiac cycle. The size and the amplitude of the pulsating blood pressure can be adjusted by adjusting the length and the elastic coefficient of the corrugated pipe (6). The frequency of the pulsating blood pressure can be adjusted by adjusting the rotation speed of the main shaft (11). In the process, the force for restoring the connecting rod (9) to the original position comes from the elastic force of the corrugated pipe (6). As the main shaft groove-shaped lug (10) is symmetrical about the center of the main shaft (11), the reaction force of the main shaft groove-shaped lug (10) received by the connecting rod (9) is also symmetrical about the center of the main shaft (11), and the main shaft (11) cannot be subjected to unbalanced force during high-speed rotation, so that the vibration stability is good. The application scene of the beating mechanism of the device is not limited to artificial heart and ventricular assist, and the device can be applied to or slightly changed on the basis of the invention in the mechanical field of centrifugal impellers such as centrifugal compressors, centrifugal pumps, centrifugal fans, centripetal turbines and centripetal water turbines which need to provide pulsating pressure.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that are within the spirit and principle of the present invention are intended to be included therein.
Claims (2)
1. A pulsating centrifugal blood pump applied to artificial heart and ventricle assistance is characterized by comprising a blood pump system and a pulsating system which work in a coupling way;
the blood pump system comprises a pump shell (2), a base (8), a corrugated pipe (6), an impeller (18) and a main shaft (11);
the pulsation system comprises a pump shell (2), a corrugated pipe (6), a base (8), a connecting rod (9) and a main shaft (11);
the pump shell (2) is characterized in that 2 groups of pump shell platforms (4) and pump shell cylinders (5) which are symmetrically distributed on the circumference relative to the pump shell inlet (1), wherein the pump shell platforms (4) and the pump shell cylinders (5) are in one-to-one correspondence;
the base (8) is characterized in that a base center hole (17) is formed, 2 groups of base platforms (14) and base platform holes (15) which are symmetrically distributed relative to the base center hole (17) are arranged on the circumference, the base platforms (14) and the base platform holes (15) are in one-to-one correspondence, and a base rectangular hole (16) is formed below each base platform (14);
the impeller (18) is characterized in that an impeller center hole (19) is formed, a plurality of impeller blades (20) are uniformly distributed in the circumferential direction, and the impeller blades (20) are spiral flow channels;
the connecting rod (9) is characterized in that a connecting rod pump shell hole (12) and a connecting rod base hole (13) are formed, and the connecting rod (9) is of a broken line type or an arc line type;
the spindle (11) is characterized by being provided with a spindle groove-shaped lug (10), the section of the spindle groove-shaped lug (10) is rectangular or double-round-head groove-shaped, and the spindle groove-shaped lug (10) is centrosymmetric with respect to the spindle (11);
the blood pump system is connected in the following mode: the bottom surface of the pump shell (2) is fixedly connected with a cylindrical corrugated pipe (6), the other surface of the corrugated pipe (6) is fixedly connected with a base (8), the pump shell (2), the corrugated pipe (6) and the base (8) form a closed pump cavity, and a main shaft (11) penetrates through a central hole (19) of an impeller and is fixedly connected with the impeller (18);
the connection mode of the pulse system is as follows: the connecting rod (9) penetrates through a base rectangular hole (16) of the base (8), is sleeved on a pump shell cylinder (5) of the pump shell (2) through a connecting rod pump shell hole (12), is not fixedly connected and can rotate relatively; the bolt (7) passes through a base platform hole (15) of the base (8) and a connecting rod base hole (13) of the connecting rod (9) to connect the connecting rod (9) and the base (8) without fixed connection and can rotate relatively.
2. The pulsatile centrifugal blood pump of claim 1, wherein said pulsatile system structural parameter relationship is: the length of the main shaft groove-shaped convex block (10) is l1The length of the minimum radial distance between the connecting rod (9) and the main shaft (11) is l2The axial distance between the base (8) and the groove-shaped lug (10) of the main shaft is l3The maximum axial distance between the base (8) and the pump shell cylinder (5) is l4The maximum contraction of the length of the corrugated pipe is delta lmaxThey satisfy the following formula:
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CN113318344B true CN113318344B (en) | 2022-07-01 |
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1528472A (en) * | 2003-09-30 | 2004-09-15 | 韩国纽哈特生物有限公司 | External heart-lung life-supporting system with two beating pump |
CN105246522A (en) * | 2013-03-15 | 2016-01-13 | 华思科公司 | Thoracic aorta ventricular assist system |
CN107441573A (en) * | 2017-07-20 | 2017-12-08 | 山东大学 | A kind of axial-flow type magnetic suspension blood pump with pulsation speed governing feature |
CN112156255A (en) * | 2020-10-14 | 2021-01-01 | 北京航空航天大学 | Magnetic suspension centrifugal blood pump with integrated extracorporeal circulation magnetic wheel |
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US9095428B2 (en) * | 2012-06-08 | 2015-08-04 | Cameron International Corporation | Artificial heart system |
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Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1528472A (en) * | 2003-09-30 | 2004-09-15 | 韩国纽哈特生物有限公司 | External heart-lung life-supporting system with two beating pump |
CN105246522A (en) * | 2013-03-15 | 2016-01-13 | 华思科公司 | Thoracic aorta ventricular assist system |
CN107441573A (en) * | 2017-07-20 | 2017-12-08 | 山东大学 | A kind of axial-flow type magnetic suspension blood pump with pulsation speed governing feature |
CN112156255A (en) * | 2020-10-14 | 2021-01-01 | 北京航空航天大学 | Magnetic suspension centrifugal blood pump with integrated extracorporeal circulation magnetic wheel |
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