CN113288384A - Self-assembled injection type intervertebral fusion device in vivo - Google Patents
Self-assembled injection type intervertebral fusion device in vivo Download PDFInfo
- Publication number
- CN113288384A CN113288384A CN202110518844.5A CN202110518844A CN113288384A CN 113288384 A CN113288384 A CN 113288384A CN 202110518844 A CN202110518844 A CN 202110518844A CN 113288384 A CN113288384 A CN 113288384A
- Authority
- CN
- China
- Prior art keywords
- cavity
- fusion
- state
- injection
- cavity part
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
- A61B17/8825—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by syringe details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
- A61B17/7094—Solid vertebral fillers; devices for inserting such fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
- A61B17/7097—Stabilisers comprising fluid filler in an implant, e.g. balloon; devices for inserting or filling such implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8802—Equipment for handling bone cement or other fluid fillers
- A61B17/8841—Tools specially adapted to engage a prosthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2/4611—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Prostheses (AREA)
Abstract
The invention discloses an in vivo self-assembled injection type intervertebral fusion device, which comprises: the fusion device comprises a fusion structure used for being implanted into an intervertebral space, the fusion structure is provided with a first cavity part used for filling bone grains and a second cavity part used for filling bone cement, the second cavity part surrounds the first cavity part, at least part of the injector is communicated with the fusion structure, the fusion structure is provided with a first state and a second state, the first cavity part and the second cavity part are not filled in the first state and are in a contraction shape, and the first cavity part and the second cavity part are filled in the second state and are in an expansion shape. The bone particles and the bone cement are injected into the fusion structure through the injector, so that the fusion structure is changed from a contraction state to an expansion state, and the fusion structure is changed in shape and volume after being implanted into a human body, thereby realizing the effect of the fusion cage with supporting and bone induction capabilities for intervertebral implantation fusion under a minimally invasive channel, and having the advantages of simple operation, safety and stability.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to an in-vivo self-assembled injection type intervertebral fusion device.
Background
With the development of modern spinal endoscopy technology, minimally invasive intervertebral disc surgery has advanced significantly. The traditional large incision surgery has been gradually replaced by the minimally invasive surgery with small channels, and now, the surgery can be realized through an operation channel with the diameter of about 6 mm with the assistance of an endoscope. Treatment of degenerative lumbar diseases sometimes requires intervertebral fusion procedures to re-establish spinal stabilization in addition to discectomy and neural decompression. The intervertebral fusion operation of the existing open surgery generally needs to place a square-shaped intervertebral fusion cage into an intervertebral space and fill bone particles or bone inducing materials into the space inside and around the fusion cage to promote the fusion of adjacent vertebral bodies. Most of the interbody fusion cages for open surgery are hollow block-like supports filled with autologous bone materials, the size and height of the interbody fusion cages are completely adapted to the size of the corresponding intervertebral space, the size and the volume are large, the height of the intervertebral discs of the lower lumbar of normal people is generally about 10-20 mm, if an operation channel is only 6 mm, an interbody fusion cage with the height exceeding 10mm cannot be placed, and with the mature application of the intervertebral foramen endoscope technology, the problem that how to realize intervertebral implantation fusion under a minimally invasive channel needs to be solved.
Disclosure of Invention
The present invention is directed to solve at least one of the problems of the prior art, and to this end, the present invention provides an in vivo self-assembled injection type intervertebral fusion device, comprising: an injector and a fusion cage comprising a fusion construct for implantation in an intervertebral space, the fusion construct having a first cavity portion for filling with bone particles and a second cavity portion for filling with bone cement, the second cavity portion surrounding the first cavity portion, at least a portion of the injector being in communication with the fusion construct, the fusion construct having a first state in which the first and second cavity portions are unfilled in a contracted state and a second state in which the first and second cavity portions are filled in an expanded state.
The invention has the advantages that the bone particles and bone cement are injected into the fusion structure through the injector, so that the fusion structure is changed from a contraction state to an expansion state, the fusion structure is changed in shape and volume after being implanted into a human body, the effects of supporting and bone induction capability of intervertebral implantation fusion under a minimally invasive channel are realized, and the invention has the advantages of simple operation, safety and stability.
In some embodiments of the invention, the fusion cage further comprises a channel structure in communication with the fusion cage, and at least a portion of the injector is in communication with the fusion cage through the channel structure.
In some embodiments of the invention, the injector has an injection cavity, the channel structure comprises a first channel portion, and the injection cavity, the first channel portion and the first cavity portion are in communication in that order.
In some embodiments of the present invention, the channel structure further comprises a second channel portion, and the injection cavity, the second channel portion and the second cavity portion are sequentially communicated.
In some embodiments of the present invention, the first chamber portion is a mesh-bag-shaped structure woven by expandable polymer materials.
In some embodiments of the present invention, the second cavity is made of a polymer material, and the channel structure is made of a metal material.
Drawings
The invention is further described in the following with reference to the accompanying drawings, it is obvious that the drawings in the following description are some embodiments of the invention, and that for a person skilled in the art, other drawings can be derived from these drawings without inventive effort.
FIG. 1 is a schematic view of a fusion construct of the present invention in a first state;
FIG. 2 is a schematic diagram of a fusion construct of the present invention in a second state;
FIG. 3 is a schematic diagram of the first chamber section of the present invention before filling by injection;
FIG. 4 is a schematic representation of the first lumen portion of the present invention expanded following injection filling;
FIG. 5 is a schematic diagram of the fill injection configuration of the first and second chambers of the present invention;
fig. 6 is a schematic view of the fusion construct of the present invention after implantation into an intervertebral space.
In the figure: a fusion construct 100, a first lumen portion 110, a second lumen portion 120, a channel construct 200, a first channel portion 210, a second channel portion 220, a reservoir 300, an infusion lumen 310, an infusion handle 400.
Detailed Description
The following detailed description of the present invention is given for the purpose of better understanding technical solutions of the present invention by those skilled in the art, and the present description is only exemplary and explanatory and should not be construed as limiting the scope of the present invention in any way.
It is to be understood that, herein, if there is an orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", "front", "rear", "inner", "outer", "top", etc., based on the orientation or positional relationship shown in the drawings, it is merely for convenience of describing and simplifying the present invention, and it is not intended to indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, is not to be construed as limiting the present invention. Herein, the terms "first", "second", and the like are used for distinguishing different objects, not for describing a particular order.
It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. In the description of the present invention, unless otherwise explicitly limited, terms such as arrangement, installation, connection and the like should be understood in a broad sense, and those skilled in the art can reasonably determine the specific meanings of the above terms in the present invention in combination with the specific contents of the technical solutions.
Reference will now be made in detail to the present preferred embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to like elements throughout.
Referring to fig. 1 to 6, the present invention provides an in vivo self-assembled injection type intervertebral fusion device, comprising: the fusion cage comprises a fusion structure 100 for implanting in an intervertebral space, the fusion structure 100 comprises a first cavity part 110 for filling bone particles and a second cavity part 120 for filling bone cement, the second cavity part 120 surrounds the first cavity part 110, at least part of the injector is communicated with the fusion structure 100, the fusion structure 100 has a first state and a second state, in the first state, the first cavity part 110 and the second cavity part 120 are not filled and are in a contraction shape, and in the second state, the first cavity part 110 and the second cavity part 120 are filled and are in an expansion shape.
Further, the injector includes a storage 300 and an injection handle 400, the storage 300 is used for storing bone particles or bone cement, further, the storage 300 has an injection cavity 310, the injection handle 400 at least partially extends into the injection cavity 310, and the bone particles or bone cement in the injection cavity 310 are compressed to inject the bone particles or bone cement into the fusion structure 100. In other embodiments of the invention, the bone particles or cement are injected in a pneumatic injection mode, preferably a slow injection mode with low air pressure.
Preferably, the cage further comprises a channel structure 200, the channel structure 200 being in communication with the cage 100, and at least part of the injector being in communication with the cage 100 through the channel structure 200.
Further preferably, the channel structure 200 includes a first channel portion 210 and a second channel portion 220, the injection cavity 310 is sequentially communicated with the first channel portion 210 and the first cavity portion 110, and the injection cavity 310 is also sequentially communicated with the second channel portion 220 and the second cavity portion 120.
When injecting the bone particles, the bone particles are stored in the injection cavity 310 of the storage member 300, the injection handle 400 is pressed, the bone particles are injected from the injection cavity 310 into the first cavity part 110 through the first channel 210, and the first cavity part 110 is filled with the bone particles to be expanded.
When the cement is injected, the cement is stored in the injection cavity 310 of the storage member 300, the injection handle 400 is pressed, the cement is injected from the injection cavity 310 into the second cavity 120 through the second passage 220, and the cement fills the second cavity 120 to be expanded.
Preferably, the first chamber 110 is a net bag-shaped structure woven by expandable polymer materials. Further preferably, the material of the first cavity 110 is carbon fiber, and in some other embodiments of the present invention, the first cavity 110 may be made of any other polymer material such as polyetheretherketone.
Preferably, the material of the second cavity 120 is a polymer material, and the material of the channel structure 200 is a metal material. Further preferably, the material of the second cavity 120 is carbon fiber, and in some other embodiments of the present invention, the second cavity 120 may be made of any other polymer material such as polyetheretherketone. Further preferably, the channel structure 200 is made of titanium alloy.
The implementation method of the self-assembled injection type intervertebral fusion device in vivo comprises the following steps:
1) the patient takes the prone position and is locally anesthetized.
2) And (3) performing intervertebral foramen puncture on the outgoing side of the midline of the pathological change section in a 10-13 cm direction to the pathological change gap.
3) The puncture position is determined under perspective and slightly adjusted according to the situation, so that the puncture needle is positioned on the upper articular process of the lower lumbar.
4) And (5) placing a gradual expansion channel, and finally placing a 6.5 mm working channel.
5) The superior articular process of the inferior lumbar vertebra is cut a little by a trepan to enlarge the exposure of the intervertebral foramen.
6) The intervertebral disc annulus fibrosus is treated with radiofrequency electricity, and part of ligamentum flavum is removed with rongeur to reveal nerve function.
7) Discectomy decompression is performed below the nerve roots.
8) And (4) arranging a reverse scraping key and an expandable end plate reamer to treat the end plate.
9) Selecting an in vivo self-assembled injection type intervertebral fusion device with proper length, placing the device into an intervertebral space along a channel, and determining the position in a perspective way.
10) Bone pellet filling is performed under the minimally invasive canal, and the first cavity 110 is filled with bone pellets.
11) Bone cement is then injected into the second cavity 120, completing the peripheral fill.
12) The filling is observed satisfactorily in perspective, and the filling operation can be stopped when the fusion cage is completely unfolded.
The first cavity part 110 is filled with autologous or allogeneic cancellous bone grains through an injector to form a pressed bone graft, so that a central part is formed, and the second cavity part 120 surrounded by the periphery of the first cavity part 110 is injected with bone cement to form a peripheral support structure so as to be self-assembled into a fusion cage with a support function and bone induction capability in the intervertebral space.
The principles and embodiments of the present invention are explained herein using specific examples, which are presented only to assist in understanding the method and its core concepts of the present invention. It should be noted that there are no specific structures but a few objective structures due to the limited character expressions, and that those skilled in the art may make various improvements, decorations or changes without departing from the principle of the invention or may combine the above technical features in a suitable manner; such modifications, variations, combinations, or adaptations of the invention using its spirit and scope, as defined by the claims, may be directed to other uses and embodiments.
Claims (6)
1. An in vivo self-assembling injection intervertebral fusion device, comprising: an injector and a fusion cage comprising a fusion construct for implantation in an intervertebral space, the fusion construct having a first cavity portion for filling with bone particles and a second cavity portion for filling with bone cement, the second cavity portion surrounding the first cavity portion, at least a portion of the injector being in communication with the fusion construct, the fusion construct having a first state in which the first and second cavity portions are unfilled in a contracted state and a second state in which the first and second cavity portions are filled in an expanded state.
2. The in vivo self-assembling injection intervertebral fusion device of claim 1 wherein: the cage further includes a channel structure in communication with the cage structure, through which at least a portion of the injector communicates with the cage structure.
3. The in vivo self-assembling injection intervertebral fusion device of claim 2 wherein: the injector is provided with an injection cavity, the channel structure comprises a first channel part, and the injection cavity, the first channel part and the first cavity part are communicated in sequence.
4. The in vivo self-assembling injection intervertebral fusion device of claim 3 wherein: the channel structure further comprises a second channel part, and the injection cavity, the second channel part and the second cavity part are communicated in sequence.
5. The in vivo self-assembling injection intervertebral fusion device of any one of claims 1 to 4, wherein: the first cavity part is a net bag-shaped structure woven by expandable high polymer materials.
6. The in vivo self-assembling injection intervertebral fusion device of any one of claims 1 to 4, wherein: the second cavity part is made of high polymer materials, and the channel structure is made of metal materials.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110518844.5A CN113288384A (en) | 2021-05-12 | 2021-05-12 | Self-assembled injection type intervertebral fusion device in vivo |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110518844.5A CN113288384A (en) | 2021-05-12 | 2021-05-12 | Self-assembled injection type intervertebral fusion device in vivo |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113288384A true CN113288384A (en) | 2021-08-24 |
Family
ID=77321550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110518844.5A Pending CN113288384A (en) | 2021-05-12 | 2021-05-12 | Self-assembled injection type intervertebral fusion device in vivo |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113288384A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103655010A (en) * | 2013-11-20 | 2014-03-26 | 苏州博习医疗科技有限公司 | Intervertebral filling fusion device |
| CN110236743A (en) * | 2019-04-24 | 2019-09-17 | 宁波华科润生物科技有限公司 | A kind of minimally invasive fusion device of spontaneous coagulation sealing |
| CN112137707A (en) * | 2020-09-27 | 2020-12-29 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | A inflation sacculus and medical device for intervertebral disc plasty |
-
2021
- 2021-05-12 CN CN202110518844.5A patent/CN113288384A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103655010A (en) * | 2013-11-20 | 2014-03-26 | 苏州博习医疗科技有限公司 | Intervertebral filling fusion device |
| CN110236743A (en) * | 2019-04-24 | 2019-09-17 | 宁波华科润生物科技有限公司 | A kind of minimally invasive fusion device of spontaneous coagulation sealing |
| CN112137707A (en) * | 2020-09-27 | 2020-12-29 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | A inflation sacculus and medical device for intervertebral disc plasty |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US7156877B2 (en) | Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs | |
| EP1985260B1 (en) | Intervertebral disc prosthesis | |
| US6733533B1 (en) | Artificial spinal disc | |
| US8221460B2 (en) | Methods and devices for interbody spinal stabilization | |
| US7727263B2 (en) | Articulating spinal implant | |
| CN102395332B (en) | Minimally invasive expandable contained vertebral implant and method | |
| US20110319996A1 (en) | Expandable vertebral body replacement device and method | |
| US20060293749A1 (en) | Interbody fusion ring and method of using the same | |
| US20080009944A1 (en) | Spinal implant and method of use | |
| US7128746B2 (en) | Device for treating intervertebral disc herniations | |
| KR20020033605A (en) | Prosthetic Spinal Disc Nucleus Having a Shape Change Characteristic | |
| US20090264939A9 (en) | Instrument set and method for performing spinal nuclectomy | |
| US20060293561A1 (en) | System and methods for intervertebral disc surgery | |
| CN113288384A (en) | Self-assembled injection type intervertebral fusion device in vivo | |
| WO2021147582A1 (en) | Percutaneous intervertebral fusion system | |
| US11759328B2 (en) | Expandable motion preservation spacer | |
| CN201361103Y (en) | Perkutan parasacral interbody fusion cage | |
| AU2002366001B2 (en) | Intervertebral disc prosthesis | |
| AU2002315423A1 (en) | Methods and devices for interbody spinal stabilization |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20210824 |