CN113274099B - Cutting device for treating atherosclerosis obliterans - Google Patents
Cutting device for treating atherosclerosis obliterans Download PDFInfo
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- CN113274099B CN113274099B CN202110581548.XA CN202110581548A CN113274099B CN 113274099 B CN113274099 B CN 113274099B CN 202110581548 A CN202110581548 A CN 202110581548A CN 113274099 B CN113274099 B CN 113274099B
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- cutting
- drug delivery
- catheter sheath
- cutting assembly
- locking
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/32075—Pullback cutting; combined forward and pullback cutting, e.g. with cutters at both sides of the plaque
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3415—Trocars; Puncturing needles for introducing tubes or catheters, e.g. gastrostomy tubes, drain catheters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B2017/320716—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions comprising means for preventing embolism by dislodged material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B2017/320741—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions for stripping the intima or the internal plaque from a blood vessel, e.g. for endarterectomy
Abstract
The invention relates to a cutting device for treating atherosclerosis obliterans, and relates to the technical field of medical instruments. The cutting device includes a lever, a cutting assembly, a catheter sheath, and a locking mechanism. The lever has a cutting end and a gripping end. The cutting assembly is fixed to the cutting end. The cutting assembly is used to cut atherosclerotic plaque and to collect plaque cut by the cutting assembly. The operating rod is sleeved in the catheter sheath. The locking mechanism is used for locking the operating rod and the catheter sheath. When the locking mechanism is in the unlocked state, the cutting assembly can be positioned in the catheter sheath and in a furled state; when the locking mechanism is in the locked state, the cutting assembly is positioned outside the catheter sheath and in the open state. The cutting device is simple to operate, can realize natural release of the cutting assembly without an additional instrument so as to effectively remove atherosclerotic plaques, and is short in treatment time, small in wound and not easy to bring secondary symptoms when used for treating atherosclerotic occlusive disease.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a cutting device for treating atherosclerosis obliteration.
Background
Atherosclerosis is a systemic disease associated with a disorder of lipid metabolism characterized by the entrance of lipids in the blood into the arterial wall and deposition on the intima to form an atheromatous plaque, resulting in thickening and hardening of the arteries.
The atherosclerosis of China is in an ascending situation and is often seen in middle-aged and elderly people. Atherosclerosis is a common disease that seriously compromises human health. The sites of atherosclerosis include coronary artery, aorta, cerebral artery, renal artery, etc. Coronary atherosclerosis and heart disease caused by myocardial ischemia and anoxia due to coronary atherosclerosis and luminal stenosis account for the majority of coronary heart diseases, so the coronary atherosclerotic heart disease is usually called coronary heart disease for short. Coronary atherosclerosis causes artery lumen stenosis, even lumen occlusion due to secondary change, thus causing diseases such as myocardial infarction, cerebral infarction, aneurysm, hypertension and the like, and causing great pain to patients.
At present, the atherosclerosis obliteration is generally treated by adopting operative intervention, thrombolysis, stent implantation or bypass transplantation (coronary artery bypass surgery), percutaneous transluminal balloon dilatation and the like. The bypass grafting operation process is complex, the wound is large, complications easily exist, and non-emergency situations are generally not considered. Implanted stents are at risk of detachment and are prone to restenosis, with no more effective treatment after restenosis. Balloon dilation is not ideal for symptomatic atherosclerotic plaque effects.
Therefore, there is a need for an interventional medical device that does not require implantation, is less traumatic during surgery, has a short duration of action, and can effectively remove atherosclerotic plaques, thereby being useful for treating atherosclerotic occlusive disease.
Disclosure of Invention
The invention aims to provide a cutting device which does not need to be implanted, has small trauma during operation and short action time, can effectively remove atherosclerotic plaques and can be used for treating atherosclerotic occlusive disease.
In order to achieve the purpose, the invention provides the following technical scheme:
the present invention provides a cutting device for treating atherosclerotic occlusive disease, the cutting device comprising:
an operating rod having a cutting end and a gripping end;
a cutting assembly fixedly attached to the cutting end, the cutting assembly having a deployed configuration and a stowed configuration, the cutting assembly including a cutting blade for cutting atherosclerotic plaque and a collection member fixedly attached to the cutting blade, the collection member including a collection portion at a distal end of the cutting blade, a connector for connecting a proximal end of the collection portion to the cutting end;
the catheter sheath is sleeved on the operating rod and is connected with the operating rod in a sliding way, and the holding end is always positioned outside the catheter sheath;
a locking mechanism for locking the relative positions of the operating rod and the catheter sheath;
when the locking mechanism is in the unlocked state, the cutting assembly may be positioned within the catheter sheath and in a collapsed state; when the locking mechanism is in the locked state, the cutting assembly is positioned outside the catheter sheath and in an open state.
The operating rod is arranged to push or withdraw the cutting assembly out of or back into the catheter sheath, so that the cutting assembly can be naturally released after being pushed out of the catheter sheath, and atherosclerotic plaques can be conveniently cut. The cutting assembly can collect plaque that falls off after being cut by the cutting assembly, so as to prevent the plaque from causing secondary thrombus along with blood flow.
The locking mechanism facilitates locking of the relative positions of the operating rod and the catheter sheath after the cutting assembly is pushed out of the catheter sheath.
The cutting device for treating the atherosclerotic occlusive disease does not need to be implanted into a blood vessel, is simple to operate, can realize the natural release of the cutting assembly without an additional instrument so as to effectively remove the atherosclerotic plaque, and has short treatment time, small wound and difficult secondary symptoms.
Preferably, the cutting blade is fixedly attached at a distal end of the connector and/or at a proximal end of the collecting portion. The atherosclerotic plaque cut by the cutting blade may immediately enter the collection portion with the blood flow.
Preferably, the distal end of the connecting piece is fixedly connected with the proximal end of the collecting part, the distal ends of every two connecting pieces are connected to form a unit, and a plurality of units are distributed along the circumferential direction of the cutting end.
Specifically, when the cutting assembly is the state of expanding, the one end of connecting piece all with cutting end fixed connection, the other end to keeping away from the direction diffusion of cutting end. The connecting piece forms and follows a plurality of petal forms that cutting end circumference evenly set up have fine stability after cutting assembly expandes.
Preferably, the collecting means includes 5 to 7 sets of the units arranged uniformly in a circumferential direction of the operation rod.
Further preferably, each connecting piece is fixedly connected with a cutting blade, and when the cutting assembly is in a deployed state, an included angle formed between two cutting blades on the same unit is 50-70 degrees, so that the cutting assembly can cut off plaques uniformly after being attached to the plaques, and the cutting assembly can be conveniently and quickly retracted into the catheter sheath.
It is further preferred that the cutting blades on the same attachment form an angle of 55-65 ° when the cutting member is in the deployed state, so that as much plaque as possible is removed.
In some embodiments of the invention, the cutting blade is bonded to the distal end of the connector.
Preferably, the cross-sectional area of the collecting portion tapers from its proximal end to its distal end when the cutting assembly is in the deployed state.
In some embodiments of the present invention, when the cutting assembly is in the deployed state, the collecting portion is conical, the proximal ends of the connecting members are all fixedly connected to the cutting end, and the distal end of the connecting member spreads away from the cutting end and is connected to an end of the collecting portion opposite to the conical tip, so as to facilitate rapid deployment and rapid retraction of the cutting assembly into the catheter sheath.
Preferably, the cutting assembly is generally elliptical when deployed, facilitating rapid deployment and rapid retraction of the cutting assembly into the catheter sheath.
Preferably, the distal end of the collecting part is provided with a guide hole through which a guide wire or a balloon dilatation catheter can pass.
In some embodiments of the invention, the collection portion is a filter screen that intercepts plaque cut by the cutting blade, and blood flow is allowed to pass through the filter aperture.
More specifically, one end of the conical tip of the filter screen is provided with a guide hole through which a guide wire or a balloon dilatation catheter can pass.
The arrangement of the guide hole ensures that the cutting device for treating the atherosclerosis obliterans can be matched with a guide wire or a balloon dilatation catheter for use, so that the success rate of the operation is improved, and the operation is convenient and quick.
Preferably, the locking mechanism comprises a first locking portion disposed at a gripping end and a second locking portion disposed at an end of the catheter sheath near the gripping end, the first locking portion and the second locking portion being cooperatively lockable.
In some embodiments of the invention, the first and second locking portions snap-fit; the first locking part is provided with a bayonet, and the second locking part is provided with a chuck matched with the bayonet.
In some embodiments of the invention, the first locking portion and the second locking portion are threadedly connected; and one end of the first locking part, which is close to the second locking part, is fixedly provided with a boss, the second locking part is provided with a connecting groove matched with the boss, and the boss is in threaded connection with the connecting groove.
Preferably, the cutting device further comprises a drug delivery channel for injecting an anticoagulant drug and/or a thrombolytic drug into the atherosclerotic plaque site, the drug delivery channel being located outside the catheter sheath.
The medicine conveying channel is convenient and direct to convey medicine to the cutting part, and the cutting effect of the cutting assembly on the plaque is favorably improved.
In some embodiments of the present invention, the cutting device includes a membrane having a distal end welded or bonded to the sheath to form a sealed end, a proximal end of the membrane is connected to the drug delivery device, the drug delivery channel is formed between the membrane and the sheath, and a portion of the membrane near the sealed end is provided with a plurality of drug delivery pores.
In some embodiments of the present invention, the drug delivery channel includes an annular body wrapped on the outer circumferential surface of the catheter sheath, a plurality of drug delivery micro-tubes are uniformly arranged inside the annular body along the circumferential direction of the annular body, the distal end of each drug delivery micro-tube is a sealed end, the proximal end of each drug delivery channel is communicated with the drug feeding device, and a plurality of drug delivery micro-holes are formed in the side wall of each drug delivery micro-tube near the sealed end.
Specifically, the drug delivery micropores are uniformly distributed along the circumferential direction and the axial direction of the catheter sheath, so that the application area of the drug can be increased, the drug can cover the focus as comprehensively as possible, and the treatment effect is ensured.
Because the drug delivery channel is usually made of soft materials, if the drug delivery channel is arranged into a complete annular channel, the drug delivery channel can collapse and be attached to the catheter sheath when no drug is introduced, so that the surface of the catheter sheath is not smooth and flat, the movement of the catheter sheath in a blood vessel can be influenced, meanwhile, because the volume of the complete annular channel is large, more drugs are needed, and drug waste is easily caused.
Specifically, the annular body is fixed on the outer peripheral surface of the catheter sheath in a welding or bonding mode.
Specifically, on the cross section of the annular body, the drug delivery micro-tubes are uniformly distributed at intervals; in the axial direction of the annular body, a plurality of drug delivery micro-holes are uniformly distributed on each drug delivery micro-tube at intervals, so that the drug application area can be increased as much as possible, the drug can cover the focus as comprehensively as possible, and the treatment effect is ensured.
Due to the application of the technical scheme, compared with the prior art, the invention has the following advantages:
the cutting device for treating atherosclerosis obliterans provided by the invention can realize natural release of the cutting component without implanting a blood vessel or using an additional instrument, and can directly filter and collect the atherosclerotic plaques after being cut, so that the atherosclerotic plaques are effectively removed, the operation is simple and convenient, the whole treatment process is short in time, the wound is small, and secondary symptoms are not easily brought.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
FIG. 1 is a schematic structural view of a cutting assembly provided in embodiment 1 of the present invention before release;
FIG. 2 is an enlarged view of a portion of FIG. 1 at location II;
fig. 3 is a schematic structural diagram of the cutting assembly provided in embodiment 1 of the present invention after being released;
FIG. 4 is a schematic view of a cutting assembly provided in embodiment 1 of the present invention in a blood vessel;
FIG. 5 is a schematic structural view of a cutting assembly provided in embodiment 2 of the present invention before release;
FIG. 6 is a schematic view of a released cutting assembly according to embodiment 2 of the present invention;
fig. 7 is a schematic structural view of a drug delivery channel provided in example 1 of the present invention;
FIG. 8 is a schematic cross-sectional view of the closed end of the drug delivery channel provided in example 1 of the present invention;
FIG. 9 is a schematic cross-sectional view taken at location III of FIG. 7;
FIG. 10 is an enlarged partial front view of the drug delivery channel at position III of FIG. 7;
FIG. 11 is an enlarged partial perspective view of the drug delivery channel at position III of FIG. 7;
FIG. 12 is a perspective view of FIG. 11;
FIG. 13 is a partial cross-sectional view of FIG. 11;
icon: 1-cutting device for treating atherosclerotic occlusive disease, 11-operating rod, 111-cutting end, 112-holding end, 113-first locking portion, 114-handle, 115-bayonet, 12-cutting component, 121-connecting piece, 122-cutting blade, 123-filter screen, 124-guide hole, 13-catheter sheath, 131-second locking portion, 132-chuck, 14-drug delivery channel, 141-drug delivery micropore, 142-annular body, 143-drug delivery microtubule, 144-sealing end, 15-three-way valve, 2-guide wire, 3-blood vessel, 4-plaque, 5-cutting device for treating atherosclerotic occlusive disease, 516-boss, 533-connecting groove.
Detailed Description
In the following, only certain exemplary embodiments are briefly described. As those skilled in the art will recognize, the described embodiments may be modified in various different ways, all without departing from the spirit or scope of the embodiments of the invention. Accordingly, the drawings and description are to be regarded as illustrative in nature, and not as restrictive.
In the description of the embodiments of the present invention, it should be understood that the terms "inside", "outside", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience in describing the embodiments of the present invention and simplifying the description, but do not indicate or imply that the referred devices or elements must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the embodiments of the present invention.
Furthermore, the terms "proximal" and "distal" are described in terms of an operator, with the side of the gripping end being the proximal end and the side of the cutting end being the distal end.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or to implicitly indicate the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the embodiments of the present invention, "a plurality" means two or more unless specifically limited otherwise.
In the embodiments of the present invention, unless otherwise explicitly specified or limited, the terms "mounted," "connected," "fixed," and the like are to be construed broadly, e.g., as being fixedly connected, detachably connected, or integrated; the connection can be mechanical connection, electrical connection or communication; either directly or indirectly through intervening media, either internally or in any other relationship. Specific meanings of the above terms in the embodiments of the present invention can be understood by those of ordinary skill in the art according to specific situations.
In embodiments of the invention, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may comprise the first and second features being in direct contact, or the first and second features being in contact, not directly, but via another feature therebetween. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly above and obliquely above the second feature, or simply meaning that the first feature is at a lesser level than the second feature.
The following disclosure provides many different embodiments or examples for implementing different configurations of embodiments of the invention. To simplify the disclosure of embodiments of the invention, specific example components and arrangements are described below. Of course, they are merely examples and are not intended to limit embodiments of the invention. Furthermore, embodiments of the present invention may repeat reference numerals and/or letters in the various examples, such repetition is for the purpose of simplicity and clarity and does not in itself dictate a relationship between the various embodiments and/or configurations discussed.
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings.
Example 1
Referring to fig. 1-4 and 7-13, the present embodiment provides a cutting device 1 for treating atherosclerotic occlusive disease, mainly including: a shaft 11, a cutting assembly 12 having an expanded state and a collapsed state, a catheter sheath 13, and a locking mechanism for locking the shaft 11 and the catheter sheath 13.
The locking mechanism includes a first locking portion 113 provided on the operating lever 11 and a second locking portion 131 provided on the catheter sheath 13, the first locking portion 113 and the second locking portion 131 being cooperatively lockable and unlockable. When the locking mechanism is in the unlocked state, the cutting assembly 12 may be positioned within the catheter sheath 13 and in a collapsed state; when the locking mechanism is in the locked state, the cutting assembly 12 is positioned outside the catheter sheath 13 and in the open state.
A lever 11 having a cutting end 111 and a gripping end 112. The first locking portion 113 is provided at the grip end 112.
And a cutting assembly 12 fixed to the cutting end 111. The cutting assembly 12 has a deployed state and a collapsed state, the cutting assembly 12 including a cutting blade 122 for cutting atherosclerotic plaque, and a collection member fixedly attached to the cutting blade 122, the collection member including a collection portion at a distal end of the cutting blade 122, a coupling 121 for coupling a proximal end of the collection portion to the cutting end. The collecting part in this embodiment is a filter screen 123.
The catheter sheath 13, the operating rod 11 is sleeved in the catheter sheath 13. The second locking portion 131 is disposed at an end of the catheter sheath 13 proximate the gripping end 112.
The operating rod 11 is configured to push or retract the cutting assembly 12 from within the sheath 13, such that the cutting assembly 12 is released from the sheath 13 to facilitate cutting of the atherosclerotic plaque 4. The cutting assembly 12 is capable of collecting plaque 4 dislodged by the cutting assembly 12 after cutting, to prevent the plaque 4 from causing secondary thrombosis with blood flow. The first locking portion 113 and the second locking portion 131 are configured to lock the relative positions of the operating rod 11 and the catheter sheath 13 after the cutting assembly 12 is pushed out of the catheter sheath 13. The cutting device 1 for treating atherosclerotic occlusive disease does not need to be implanted into a blood vessel 3, is simple to operate, can realize natural release of the cutting assembly 12 without the help of additional instruments so as to effectively remove atherosclerotic plaques 4, and has short treatment time, small wound and difficult secondary symptoms of the cutting device 1 for treating atherosclerotic occlusive disease.
More specifically, the holding end 112 is fixedly provided with a handle 114 for facilitating the movement of the operation rod 11 by the user.
More specifically, the catheter sheath 13 and the operation rod 11 are made of one or more of PTFE, FEP or PEBAX, so that the catheter sheath 13 and the operation rod 11 can pass through the curved lesion of the blood vessel 3 while having certain strength.
Specifically, the distal ends of the connecting members 121 are fixedly connected to the proximal end of the filter screen 123, the distal ends of every two connecting members 121 are connected to form a unit, and a plurality of units are distributed along the circumferential direction of the cutting end 111. When the cutting assembly 12 is in the unfolded state, one end of the connecting member 121 is fixedly connected to the cutting end 111, and the other end thereof is spread in a direction away from the cutting end 111. The connecting member 121 is formed in a plurality of petal shapes uniformly arranged in the circumferential direction of the cutting end 111, and has excellent stability after the cutting assembly 12 is unfolded.
Specifically, the collecting means includes 6 sets of units arranged uniformly in the circumferential direction of the operation rod 11.
Specifically, each connector 121 is fixedly connected with a cutting blade 122, when the cutting assembly 12 is in the unfolded state, an included angle formed between two cutting blades 122 on the same unit is 60 degrees, so that the cutting assembly can uniformly cut off the plaque 4 after being attached to the plaque 4, and the cutting assembly 12 can be conveniently and rapidly retracted into the catheter sheath.
More specifically, the cutting blade 122 is bonded to the distal end of the connector 121.
Specifically, when the cutting assembly 12 is in the deployed state, the cross-sectional area of the filter mesh 123 tapers from its proximal end to its distal end. The filter mesh 123 can filter the plaque 4 cut by the cutting assembly 12 from the blood.
Specifically, the filtering mesh 123 is provided with a guide hole 124 through which the guide wire 2 or the balloon dilatation catheter can pass.
More specifically, when the cutting assembly 12 is in the unfolded state, the filter screen 123 is in a conical structure, one end of the conical tip of the filter screen 123 is far away from the cutting end 111, one end of the filter screen 123 opposite to the conical tip is fixedly connected with the connecting piece 121, the plaque 4 cut by the cutting blade 122 enters the filter screen 123 along with blood, and the blood passes through the filter holes. The filter mesh 123 is conical, so that the filter mesh 123 can be conveniently and quickly retracted into the catheter sheath 13. The guide hole 124 is provided so that the cutting device 1 for treating atherosclerotic occlusion can be used with a guide wire 2 or a balloon dilatation catheter to improve the success rate of the procedure.
More specifically, the filter mesh 123 is fixed to the distal end of the connection member 121. The cutting assembly 12 is made of shape memory metal, and the cutting assembly 12 is elliptical. The cutting assembly 12 is positioned adjacent to the plaque 4 to uniformly cut the plaque 4 and allow the plaque 4 to fall into the filter mesh 123. Because the cutting assembly 12 is generally oval, the entire cutting device can simply and quickly retract the shaft 11 into the sheath 13 after the plaque 4 has been cut.
Specifically, the first locking portion 113 and the second locking portion 131 are snapped. The first locking portion 113 is provided with a bayonet 115, and the second locking portion 131 is provided with a chuck 132 matching with the bayonet 115.
In particular, the cutting device 1 for treating atherosclerotic occlusive disease further comprises a drug delivery channel 14, the drug delivery channel 14 being fixed to the catheter sheath 13, the drug delivery channel 14 being adapted for injecting anticoagulant and thrombolytic drugs into the site of the plaque 4. The setting of medicine conveying channel 14 makes things convenient for cutting assembly 12 to the cutting of plaque 4, is favorable to improving the cutting effect of cutting assembly 12 to plaque 4.
Specifically, the distal end of the drug delivery channel 14 is welded or bonded to the outer side of the catheter sheath 13 and sealed at the distal end, the proximal end is communicated with the drug delivery device, and a plurality of drug delivery micro-holes 141 are formed near the distal end of the drug delivery channel 14.
More specifically, the drug delivery channel 14 includes an annular body 142 wrapped on the outer circumferential surface of the catheter sheath 13, a plurality of drug delivery micro-tubes 143 are uniformly arranged in the annular body 142 along the circumferential direction thereof, the distal end of each drug delivery micro-tube 143 is a sealed end 144, the proximal end of each drug delivery micro-tube 143 is communicated with the drug delivery device, and a plurality of drug delivery micro-holes 141 are formed in the side wall of each drug delivery micro-tube 143 near the sealed end 144.
More specifically, the medicine feeding device is a three-way valve 15 communicated with the medicine conveying passage 14 through a pipeline.
More specifically, a three-way valve 15 can be used to introduce anticoagulant and thrombolytic drugs such as urokinase, recombinant tissue plasminogen activator, heparin, etc. into the drug delivery channel 14.
The working principle of the cutting device 1 for the treatment of atherosclerotic occlusive disease is:
before the cutting assembly 12 is released: the operating rod 11 and the cutting assembly 12 are within the catheter sheath 13. Part of the operating rod 11 and the handle 114 end are outside the catheter sheath 13.
Release of the cutting assembly 12: after the operating rod 11 is moved and the cutting assembly 12 is released naturally after being pulled out of the catheter sheath 13, the first locking portion 113 and the second locking portion 131 are matched and locked to lock the position of the cutting assembly 12, and after the operating rod 11 is unlocked, the position of the cutting assembly 12 is adjusted.
While the cutting assembly 12 is in the blood vessel 3: the cutting device 1 for treating atherosclerosis obliteration can be used together with a guide wire 2 or a balloon dilatation catheter in the vascular intervention operation. The guide wire 2 or the balloon dilatation catheter is passed out of the circular hole on the filter screen 123. As the cutting assembly 12 passes through the hardened plaque 4, the cutting blade 122 may cut the plaque 4, the plaque 4. Anticoagulant and thrombolytic drugs are injected into the drug delivery channel 14 through the three-way valve 15. After reaching the sealed end 144 of the drug delivery channel 14, the drug flows out of the drug delivery pores 141 to the site of the atherosclerotic plaque 4, facilitating the cutting assembly 12 to cut the plaque 4. The plaque 4 falls off after being cut and is intercepted by the filter screen 123, so that the secondary thrombus caused by the cut and fallen plaque 4 flowing along with the blood is prevented, and the blood flows out from the filter holes.
Example 2
Referring to fig. 5-6, the present embodiment provides a cutting device 5 for treating atherosclerotic occlusive disease, and is substantially the same as embodiment 1 except for the structure of the locking device.
A lever 11 having a cutting end 111 and a gripping end 112. The holding end 112 is provided with a first locking portion 113.
And a cutting assembly 12 fixed to the cutting end 111. The cutting assembly 12 is used to cut atherosclerotic plaque and to collect plaque cut by the cutting assembly 12.
The catheter sheath 13, the operating rod 11 is sleeved in the catheter sheath 13. The catheter sheath 13 is provided with a second locking part 131 at one end close to the holding end 112, and the first locking part 113 and the second locking part 131 can be matched and locked.
Specifically, the first locking portion 113 and the second locking portion 131 are screwed. One end of the first locking portion 113 close to the second locking portion 131 is fixedly provided with a boss 516, the second locking portion 131 is provided with a connecting groove 533 matched with the boss 516, and the boss 516 is in threaded connection with the connecting groove 533.
In particular, the cutting device 5 for treating atherosclerotic occlusive disease further comprises a drug delivery channel 14, the drug delivery channel 14 being arranged as in example 1.
The operating rod 11 is configured to push or retract the cutting assembly 12 from within the catheter sheath 13 to allow the cutting assembly 12 to be released from the catheter sheath 13 to facilitate cutting of atherosclerotic plaque. The cutting assembly 12 is capable of collecting plaque dislodged by the cutting assembly 12 after cutting to prevent the plaque from flowing with blood to cause secondary thrombosis. The first locking portion 113 and the second locking portion 131 are configured to lock the relative positions of the operating rod 11 and the catheter sheath 13 after the cutting assembly 12 is pushed out of the catheter sheath 13. The cutting device 5 for treating atherosclerotic occlusive disease does not need to be implanted into a blood vessel, is simple to operate, can realize natural release of the cutting assembly 12 without an additional instrument so as to effectively remove atherosclerotic plaques, and has short treatment time, small wound and difficult secondary symptoms.
The present invention has been described in terms of the preferred embodiment, and it is not intended to be limited to the embodiment. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (6)
1. A cutting device for treating atherosclerotic occlusive disease, the cutting device comprising:
an operating rod having a cutting end and a gripping end;
the cutting assembly is fixedly connected with the cutting end and has a spreading state and a folding state, the cutting assembly comprises a cutting blade for cutting atherosclerotic plaques and a collecting component fixedly connected with the cutting blade, the collecting component comprises a collecting part positioned at the distal end of the cutting blade, a connecting piece used for connecting the proximal end of the collecting part and the cutting end, the proximal end of the connecting piece is fixedly connected with the cutting end, the distal end of the connecting piece is fixedly connected with the proximal end of the collecting part, the distal ends of every two connecting pieces are connected to form a unit, the unit is in a petal shape, and a plurality of units are distributed along the circumferential direction of the cutting end;
the distal end of each connection is fixedly connected with a cutting blade, and when the cutting assembly is in an unfolded state, an included angle formed between the two cutting blades on the same unit is 50-70 degrees;
the catheter sheath is sleeved on the operating rod and is connected with the operating rod in a sliding way, and the holding end is always positioned outside the catheter sheath;
the locking mechanism is used for locking the relative positions of the operating rod and the catheter sheath and comprises a first locking part arranged at the holding end and a second locking part arranged at one end of the catheter sheath close to the holding end, and the first locking part and the second locking part can be matched and locked;
when the locking mechanism is in the unlocked state, the cutting assembly may be positioned within the catheter sheath and in a collapsed state; when the locking mechanism is in the locked state, the cutting assembly is positioned outside the catheter sheath and in an open state.
2. A cutting device for use in treating atherosclerotic occlusive disease as defined in claim 1, wherein the cross-sectional area of the harvesting portion decreases from the proximal end to the distal end of the cutting assembly in the deployed state.
3. The cutting device for treating atherosclerotic occlusive disease of claim 1, wherein a guide hole through which a guide wire or a balloon dilatation catheter can pass is opened at a distal end of the collecting portion.
4. The cutting device for use in treating atherosclerotic occlusive disease of claim 1, wherein the first locking portion and the second locking portion snap fit; a bayonet is arranged on the first locking part, a chuck matched with the bayonet is arranged on the second locking part,
or, the first locking portion and the second locking portion are threadedly connected; and one end of the first locking part, which is close to the second locking part, is fixedly provided with a boss, the second locking part is provided with a connecting groove matched with the boss, and the boss is in threaded connection with the connecting groove.
5. The cutting device for treating atherosclerotic occlusive disease of claim 1, further comprising a drug delivery channel for injecting an anticoagulant drug and/or a thrombolytic drug into an atherosclerotic plaque site, the drug delivery channel being located outside the catheter sheath.
6. The cutting device for treating atherosclerotic occlusive disease as claimed in claim 5, wherein the cutting device comprises a membrane having a distal end welded or bonded to the sheath to form a sealed end, a proximal end of the membrane being in communication with a drug delivery device, the membrane and the sheath forming the drug delivery channel therebetween, a portion of the membrane near the sealed end being provided with a plurality of drug delivery micropores;
or, the drug delivery channel comprises an annular body wrapped on the outer peripheral surface of the catheter sheath, a plurality of drug delivery micro-tubes are uniformly arranged in the annular body along the circumferential direction of the annular body, the far end of each drug delivery micro-tube is a sealing end, the near end of each drug delivery channel is communicated with the drug feeding device, and a plurality of drug delivery micro-holes are formed in the side wall of each drug delivery micro-tube close to the sealing end.
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| CN2020222889220 | 2020-10-14 | ||
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| CN202110581548.XA Active CN113274099B (en) | 2020-10-14 | 2021-05-27 | Cutting device for treating atherosclerosis obliterans |
| CN202121151568.5U Active CN216394193U (en) | 2020-10-14 | 2021-05-27 | Cutting device for treating atherosclerosis obliterans |
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| DE10242444A1 (en) * | 2002-09-11 | 2004-04-01 | pfm Produkte für die Medizin AG | extractor |
| JP5636114B2 (en) * | 2010-10-28 | 2014-12-03 | コヴィディエン リミテッド パートナーシップ | Substance removal device and method of use |
| CN208388703U (en) * | 2017-10-21 | 2019-01-18 | 大连大学 | A kind of intervention thrombus removing conduit |
| CN210020778U (en) * | 2019-03-14 | 2020-02-07 | 天津博安医用有限公司 | Pipe sleeve device for placing pipe and dissolving bolt |
| CN210228259U (en) * | 2019-05-19 | 2020-04-03 | 常州市三润医疗器械科技有限公司 | Thrombus removing device of thrombus removing system |
| CN211131275U (en) * | 2019-11-08 | 2020-07-31 | 刘昌伟 | Be applied to thrombectomy device of artery, vein thrombus |
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| CN113274099A (en) | 2021-08-20 |
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