CN113270138A - Method for enriching fetal free DNA for analyzing copy number variation based on bioinformatics - Google Patents
Method for enriching fetal free DNA for analyzing copy number variation based on bioinformatics Download PDFInfo
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- CN113270138A CN113270138A CN202110397074.3A CN202110397074A CN113270138A CN 113270138 A CN113270138 A CN 113270138A CN 202110397074 A CN202110397074 A CN 202110397074A CN 113270138 A CN113270138 A CN 113270138A
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/30—Detection of binding sites or motifs
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
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CN202110397074.3A CN113270138B (en) | 2021-04-13 | 2021-04-13 | Analysis method for enriching fetal free DNA (deoxyribonucleic acid) for copy number variation based on bioinformatics |
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CN202110397074.3A CN113270138B (en) | 2021-04-13 | 2021-04-13 | Analysis method for enriching fetal free DNA (deoxyribonucleic acid) for copy number variation based on bioinformatics |
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CN113270138A true CN113270138A (en) | 2021-08-17 |
CN113270138B CN113270138B (en) | 2023-09-22 |
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106591451A (en) * | 2016-12-14 | 2017-04-26 | 北京贝瑞和康生物技术股份有限公司 | Method for detecting content of fetal-free DNA, and apparatus for enforcing method |
WO2017093561A1 (en) * | 2015-12-04 | 2017-06-08 | Genesupport Sa | Method for non-invasive prenatal testing |
US20170220735A1 (en) * | 2016-02-03 | 2017-08-03 | Verinata Health, Inc. | Using cell-free dna fragment size to determine copy number variations |
CN107133495A (en) * | 2017-05-04 | 2017-09-05 | 北京医院 | A kind of analysis method and analysis system of aneuploidy biological information |
CN108573125A (en) * | 2018-04-19 | 2018-09-25 | 上海亿康医学检验所有限公司 | Method for detecting genome copy number variation and device comprising same |
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- 2021-04-13 CN CN202110397074.3A patent/CN113270138B/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017093561A1 (en) * | 2015-12-04 | 2017-06-08 | Genesupport Sa | Method for non-invasive prenatal testing |
US20170220735A1 (en) * | 2016-02-03 | 2017-08-03 | Verinata Health, Inc. | Using cell-free dna fragment size to determine copy number variations |
CN106591451A (en) * | 2016-12-14 | 2017-04-26 | 北京贝瑞和康生物技术股份有限公司 | Method for detecting content of fetal-free DNA, and apparatus for enforcing method |
CN107133495A (en) * | 2017-05-04 | 2017-09-05 | 北京医院 | A kind of analysis method and analysis system of aneuploidy biological information |
CN108573125A (en) * | 2018-04-19 | 2018-09-25 | 上海亿康医学检验所有限公司 | Method for detecting genome copy number variation and device comprising same |
Non-Patent Citations (2)
Title |
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HUDECOVA, I., ET AL.: "Maternal plasma fetal DNA fractions in pregnancies withlow and high risks for fetal chromosomal aneuploidies", 《PLOS ONE》, vol. 9, no. 2, XP055662324, DOI: 10.1371/journal.pone.0088484 * |
梅瑾;王昊;王敏;何茶英;: "二代测序技术在流产物染色体拷贝数改变检测中的应用", 浙江医学, no. 02 * |
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Inventor after: Xu Xiong Inventor after: Hu Dahui Inventor after: Ding Linfeng Inventor after: Xiao Rui Inventor after: Li Haibo Inventor after: Shi Danhua Inventor after: Tian Liyun Inventor after: Xu Jun Inventor after: Qiu Haiyan Inventor before: Xu Xiong Inventor before: Hu Dahui Inventor before: Ding Lingfeng Inventor before: Xiao Rui Inventor before: Li Haibo Inventor before: Shi Danhua Inventor before: Tian Liyun Inventor before: Xu Jun Inventor before: Qiu Haiyan |
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