CN113264271A - Evaluation gene group for gastric cancer prognosis prediction and corresponding kit - Google Patents

Evaluation gene group for gastric cancer prognosis prediction and corresponding kit Download PDF

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Publication number
CN113264271A
CN113264271A CN202110615720.9A CN202110615720A CN113264271A CN 113264271 A CN113264271 A CN 113264271A CN 202110615720 A CN202110615720 A CN 202110615720A CN 113264271 A CN113264271 A CN 113264271A
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CN
China
Prior art keywords
fixing frame
shell
fixedly connected
gastric cancer
gene group
Prior art date
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Pending
Application number
CN202110615720.9A
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Chinese (zh)
Inventor
高立明
刘娇
孔祥蕾
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First Hospital Of Qinhuangdao
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First Hospital Of Qinhuangdao
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Priority to CN202110615720.9A priority Critical patent/CN113264271A/en
Publication of CN113264271A publication Critical patent/CN113264271A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/20External fittings
    • B65D25/205Means for the attachment of labels, cards, coupons or the like
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02Internal fittings
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/28Handles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/02Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses an assessment gene group for gastric cancer prognosis prediction and a corresponding kit, comprising a shell upper cover and an upper fixing frame, wherein the rear end of the upper surface of the shell upper cover is rotatably connected with the rear surface of the shell through a hinge, a constant temperature controller is fixedly connected at the middle position of the lower end of the front surface of the shell, through holes are uniformly arranged in the upper fixing frame, a lower fixing frame is arranged right below the upper fixing frame, and the through holes are uniformly arranged in the lower fixing frame. Can make the temperature conduction more uniform, and has certain heat preservation effect when transferring the kit.

Description

Evaluation gene group for gastric cancer prognosis prediction and corresponding kit
Technical Field
The invention belongs to the technical field of kits, and particularly relates to an assessment gene group for gastric cancer prognosis prediction and a corresponding kit.
Background
The kit is a box for containing chemical reagents for detecting chemical components, drug residues, virus species and the like, is used by general hospitals and pharmaceutical enterprises, and in gastric cancer, mutation analysis of a complete exogenome discovers that the mutation rate of the RhoA gene in gastric cancer people is high, and particularly the mutation enrichment exists in diffuse subtype gastric cancer. However, there was no significant correlation between survival analysis and prognosis analysis by using the mutation of RhoA gene alone. Therefore, the prognosis of gastric cancer can only be associated with RhoA gene, and the need for prognosis prediction of gastric cancer cannot be met, so that a new prediction index having high correlation with the prognosis of gastric cancer needs to be found, and in addition, for the relationship between the gene and the prognosis in gastric cancer, there are two main types of current prediction indexes: the first type is the result of prognosis associated with mutation of a single gene, however, the index is limited by the mutation frequency of the population, for example, the mutation frequency of RhoA gene is 6.3%, and the size of the collected sample can limit the robustness of the survival analysis result; the second category relates to prognosis by mutation of certain gene combinations, and molecular markers obtained by combining multiple genes can achieve higher mutation frequency. However, the genes are usually selected from a group of genes with higher mutation frequency found in tumors, and reliable biological mechanism evidence among the genes is lacked, so that the genes are difficult to reliably apply to clinical practice.
General kit classification is clear, mark clear application method and information, but the function of kit itself is less, can not control temperature in the kit, some reagent only can preserve under certain temperature, need put into other constant temperature container, and the mount in few kit does not have the device of protection test tube, cause the damage of test tube easily, on the other hand, current kit in the use, need place the test tube in the kit, when needing to take out the test tube, because current kit and test tube upper end are in horizontal position each other, consequently difficult take out the test tube from the kit.
Disclosure of Invention
The invention aims to provide an assessment gene group for gastric cancer prognosis prediction and a corresponding kit, so as to solve the problems that the general kit proposed in the background art is clear in classification and marked with clear using methods and information, but the kit has fewer functions, the temperature in the kit cannot be controlled, part of reagents can be stored at a certain temperature and need to be put into other constant-temperature containers, and a small part of fixing frames in the kit are not provided with devices for protecting test tubes, so that the test tubes are easily damaged.
In order to achieve the purpose, the invention provides the following technical scheme: an evaluation gene group for gastric cancer prognosis prediction and a corresponding kit, which comprises a shell upper cover and an upper fixing frame, the rear end of the upper surface of the upper cover of the shell is rotationally connected with the rear surface of the shell through a hinge, the middle of the lower end of the front surface of the shell is fixedly connected with a constant temperature controller, through holes are uniformly arranged in the upper layer fixing frame, a lower layer fixing frame is arranged right below the upper layer fixing frame, through holes are uniformly arranged in the lower layer fixing frame, one corner in the shell is fixedly connected with a waterproof clapboard, the surface of a cavity formed by the lower layer fixing frame, the shell and the waterproof partition board is provided with a waterproof membrane, harmless liquid is filled in the waterproof membrane, the compressor is fixedly connected in a cavity formed by the waterproof partition board and the shell, a small hole is formed in one corner of the right surface of the shell, and a transmission line of the plug penetrates through the small hole to be connected with the compressor.
As a further scheme of the invention: the edge of the through hole of the lower layer fixing frame is provided with a concave waterproof membrane, and harmless liquid is filled in the membrane.
As a further scheme of the invention: a label is adhered to the center of the front surface of the shell.
As a further scheme of the invention: four quadrant points of the through hole in the upper fixing frame are fixedly connected with rubber cushions, and the bottom end in the through hole is provided with a protective cushion.
As a further scheme of the invention: the upper surface of the upper cover of the shell is fixedly connected with a handle.
As a further scheme of the invention: the upper layer fixing frame and the lower layer fixing frame are clamped and connected inside the shell.
As a further scheme of the invention: and a through hole in the lower-layer fixing frame is not provided with a rubber cushion.
As a further scheme of the invention: the utility model discloses a portable electronic device, including casing, casing outside surface is provided with visual window, the equal fixedly connected with in the inside both sides of casing connects the guide rail, two connect the equal sliding connection in guide rail inboard has link block, two fixedly connected with lifter plate, two in the middle of the link block equal fixed connection of lifter plate is at the support frame side, the support frame surface is provided with a plurality of connecting holes.
As a further scheme of the invention: rotate in the middle of the casing and be connected with the threaded rod, the threaded rod both ends are all rotated and are connected at the casing side, threaded rod one end transmission is connected with driving motor, threaded rod both ends surface is provided with opposite direction screw thread, the equal threaded connection in threaded rod both ends has the carriage release ring, the carriage release ring upper surface rotates and is connected with the lifter, the lifter other end rotates and connects at the sliding block lower surface, the equal fixedly connected with dead lever in carriage release ring lower extreme both sides, dead lever other end fixed connection is at the spacing ring side, spacing ring sliding connection is inside the gag lever post, the equal fixed connection in casing side in gag lever post both ends.
As a further scheme of the invention: the lifter plate both sides all are provided with the sliding tray, two the equal sliding connection of sliding tray inside has the sliding block, sliding block one side fixedly connected with telescopic link, telescopic link other end fixed connection is inboard at the sliding tray, buffer spring has been cup jointed on the telescopic link surface.
As a further scheme of the invention: the support frame upper surface both sides equal fixedly connected with sliding guide, two sliding guide intermediate sliding connection has a plurality of limiting plates, limiting plate surface all is provided with a plurality of spacing grooves, limiting plate inboard surface is provided with the inoxidizing coating, is provided with a plurality of fixed springs in the middle of two relative limiting plates.
Compared with the prior art, the invention has the following beneficial effects:
1. according to the invention, the temperature in the reagent box can be controlled through the constant temperature controller and the compressor, so that the reagent in the reagent box is in an active temperature range, the test tube can be fixed through the arranged rubber cushion, the placement is more stable, the label at the outer side of the test tube can be protected from being scratched easily, and harmless liquid is filled in the waterproof membrane through the arranged waterproof membrane, so that the temperature conduction is more uniform, and a certain heat preservation effect is achieved when the reagent box is transferred;
2. according to the invention, through the arranged threaded rod, the surfaces of two ends of the threaded rod are provided with opposite-direction threads, the threaded rod is driven to rotate by the driving motor, the moving rings at two ends of the threaded rod can keep moving in opposite directions, and the lower end of the lifting rod can be stretched by moving the positions of the moving rings, so that the height of the lifting rod can be adjusted, the height of the lifting plate can be adjusted, the height of a test tube in a middle support frame of the lifting plate can be adjusted, and a user can take the test tube out of a reagent box conveniently;
3. according to the test tube height adjusting device, the sliding block and the sliding groove are arranged, when the lifting rod is adjusted in height, the sliding block can be driven to slide in the sliding groove, when the sliding block slides, the telescopic rod and the buffer spring can be extruded towards one end, the buffer effect can be achieved on the sliding block through extrusion of the buffer spring, and therefore the situation that the height adjusting range of a test tube is too large can be effectively avoided;
4. according to the test tube lifting device, the fixing springs are arranged among the limiting plates, the test tube in the middle of the limiting plates can be clamped through the fixing springs, the lifting plate can drive the test tube to move when moving, and the rubber material is arranged inside the protective layer, so that the pressure of the limiting plates on the test tube can be reduced, and the test tube is prevented from being damaged;
5. according to the invention, through the arranged protection pads and the arrangement of the plurality of protection pads at the bottom end of the through hole, when a test tube is placed into the through hole, the impact force of the bottom end of the through hole on the test tube can be reduced, the situation that the bottom end of the test tube is broken when contacting with the through hole is avoided, and through the arranged visual windows, a user can conveniently observe the test tube situation in the reagent box by arranging the plurality of visual windows on the surface of the reagent box.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention without limiting the invention in which:
FIG. 1 is a perspective view of a kit of the present invention;
FIG. 2 is a side sectional view of the kit of the present invention;
FIG. 3 is a top view of the kit of the present invention;
FIG. 4 is a top cross-sectional view of a kit of the present invention;
FIG. 5 is a bottom view of a lifting plate of the reagent cartridge of the present invention;
FIG. 6 is a front view of a lower holder of the kit of the present invention;
FIG. 7 is an enlarged view of A in FIG. 2 of the kit of the present invention;
FIG. 8 is an enlarged view of B in FIG. 4 of the kit of the present invention.
In the figure: 1. a housing upper cover; 2. a housing; 3. an upper layer fixing frame; 4. a rubber cushion; 5. a lower layer fixing frame; 6. a water-resistant film; 7. a waterproof partition plate; 8. a thermostatic controller; 9. a compressor; 10. a hinge; 11. a non-hazardous liquid; 12. a handle; 13. a plug; 14. a label; 15. a through hole; 16. connecting the guide rails; 17. connecting the sliding block; 18. a lifting plate; 19. a lifting rod; 20. a threaded rod; 21. a moving ring; 22. a limiting rod; 23. a limiting ring; 24. fixing the rod; 25. a visible window; 26. a support frame; 27. a sliding guide rail; 28. a limiting plate; 29. a limiting groove; 30. fixing the spring; 31. a sliding groove; 32. a slider; 33. a telescopic rod; 34. a buffer spring; 35. a protective pad; 36. a protective layer; 37. and connecting the holes.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and all other embodiments obtained by a person of ordinary skill in the art without creative efforts based on the embodiments of the present invention belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front", "rear", "both ends", "one end", "the other end", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of describing the present invention and simplifying the description, but do not indicate or imply that the designated cover body or element must have a specific orientation, be configured in a specific orientation, and operate, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "connected," and the like are to be construed broadly, and for example, "connected" may be a fixed connection, a detachable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Referring to fig. 1-8, the present invention provides an assessment gene group for prognosis prediction of gastric cancer and a corresponding kit, including a housing upper cover 1 and an upper fixing frame 3, the rear end of the upper surface of the housing upper cover 1 is rotatably connected with the rear surface of the housing 2 through a hinge 10, a constant temperature controller 8 is fixedly connected in the middle of the lower end of the front surface of the housing 2, through holes 15 are uniformly arranged in the upper fixing frame 3, a lower fixing frame 5 is arranged right below the upper fixing frame 3, through holes 15 are uniformly arranged in the lower fixing frame 5, a waterproof partition plate 7 is fixedly connected to one corner of the interior of the housing 2, a waterproof membrane 6 is arranged on the surface of a cavity formed by the lower fixing frame 5, the housing 2 and the waterproof partition plate 7, a harmless liquid 11 is filled in the waterproof membrane 6, a compressor 9 is fixedly connected in a hollow space formed by the waterproof partition plate 7 and the housing 2, and a small hole is arranged at one corner of the right surface of the housing 2, the transmission line of plug 13 runs through the aperture and is connected with compressor 9, through setting up thermostatic control ware 8 and compressor 9, can realize the control of temperature in the reagent box, make reagent be in the temperature range that has activity in the box, through the rubber cushion 4 that sets up, not only can fix the test tube, it is more firm to place, the difficult fish tail of outside label that can also protect the test tube, waterproof membrane 6 through the setting, 6 inside packings of waterproof membrane have harmless liquid, can make the more even of temperature conduction, and when shifting the kit, certain heat preservation effect has.
In the invention, preferably, the edge of the through hole 15 of the lower layer fixing frame 5 is provided with the concave waterproof membrane 6 which is filled with the harmless liquid 11, so that the test tube is more stable when being placed, the temperature of the reagent in the test tube is more uniformly transferred when being controlled by the constant temperature controller 8, and the test tube has a certain heat preservation effect when being transferred.
In the present invention, it is preferable that a label 14 is attached to the front surface of the case 2 at the center, and the name, usage, effective temperature range, storage method, gene type to be detected, and the like of the reagent in the kit are recorded on the label 14.
In the invention, preferably, the four quadrant points of the through hole 15 in the upper fixing frame 3 are all fixedly connected with the rubber soft cushion 4, and the bottom end in the through hole 15 is provided with the protective cushion 35, so that the test tube can be fixed and placed more stably, and the outer label 14 of the test tube can be protected from being scratched.
In the present invention, preferably, a handle 12 is fixedly connected to the upper surface of the housing upper cover 1 for opening the reagent box and accessing the reagent.
In the present invention, it is preferable that the upper fixing frame 3 and the lower fixing frame 5 are engaged with each other inside the casing 2, and when the harmless liquid 11 leaks due to the breakage of the waterproof film 6, the upper fixing frame 3 and the lower fixing frame 5 are detached and the harmless liquid 11 and the waterproof film 6 are replaced.
In the invention, preferably, the visible window 25 is arranged on the outer side surface of the shell 2, the connecting guide rails 16 are fixedly connected to two sides inside the shell 2, the connecting sliders 17 are slidably connected to the inner sides of the two connecting guide rails 16, the lifting plate 18 is fixedly connected between the two connecting sliders 17, the two lifting plates 18 are fixedly connected to the side edges of the support frame 26, and the plurality of connecting holes 37 are arranged on the surface of the support frame 26. when the lifting plate 18 is adjusted in height, the connecting sliders 17 connected to two ends of the lifting plate 18 can slide in the connecting guide rails 16, so that the lifting plate 18 can be moved in the shell 2, and the connecting guide rails 16 are arranged at the same horizontal position on two sides in the shell 2, so that two ends of the lifting plate 18 can be ensured to be in a horizontal state when moving, thereby effectively avoiding the situation that the test tube is inclined during height adjustment, and increasing the stability of the device.
In the invention, preferably, a threaded rod 20 is rotatably connected in the middle of the shell 2, two ends of the threaded rod 20 are rotatably connected to the side of the shell 2, one end of the threaded rod 20 is in transmission connection with a driving motor, opposite-direction threads are arranged on the surfaces of two ends of the threaded rod 20, two ends of the threaded rod 20 are in threaded connection with movable rings 21, the upper surface of the movable ring 21 is rotatably connected with a lifting rod 19, the other end of the lifting rod 19 is rotatably connected to the lower surface of a sliding block 32, the threaded rod 20 is driven to rotate by the driving motor, the movable rings 21 at two ends of the threaded rod 20 can keep moving in opposite directions, the lower end of the lifting rod 19 can be stretched by moving the positions of the movable rings 21, the height of the lifting rod 19 can be adjusted, the height of the lifting plate 18 can be adjusted, the height of a test tube in the support frame 26 can be adjusted, a user can take out the test tube from the reagent box conveniently, the fixed rods 24 are fixedly connected to two sides of the lower end of the movable rings 21, the other end fixed connection of dead lever 24 is at the spacing ring 23 side, and spacing ring 23 sliding connection is inside the gag lever post 22, and the equal fixed connection in casing 2 side in gag lever post 22 both ends can drive the gag lever post 23 and slide on the gag lever post 22 when the shift ring 21 removes on threaded rod 20 surface to avoid the shift ring 21 the rotatory condition to appear.
In the invention, preferably, sliding grooves 31 are respectively arranged on two sides of the lifting plate 18, sliding blocks 32 are respectively connected in the two sliding grooves 31 in a sliding manner, an expansion link 33 is fixedly connected to one side of each sliding block 32, the other end of each expansion link 33 is fixedly connected to the inner side of each sliding groove 31, a buffer spring 34 is sleeved on the surface of each expansion link 33, the sliding blocks 32 can be driven to slide in the sliding grooves 31 when the height of the lifting rod 19 is adjusted, the expansion links 33 and the buffer springs 34 can be extruded towards one end of each sliding block 31 when the sliding blocks 31 slide, the buffer effect can be achieved on the sliding blocks 32 by extruding the buffer springs 34, and therefore, the situation that the height adjustment range of the test tube is too large can be effectively avoided.
In the invention, preferably, sliding guide rails 27 are fixedly connected to both sides of the upper surface of the support frame 26, a plurality of limiting plates 28 are slidably connected between the two sliding guide rails 27, a plurality of limiting grooves 29 are formed in the surfaces of the limiting plates 28, a protective layer 36 is arranged on the inner side surface of each limiting plate 28, a plurality of fixing springs 30 are arranged between the two opposite limiting plates 28, the fixing springs 30 are arranged between the limiting plates 28, the fixing springs 30 can clamp a test tube in the middle of each limiting plate 28, and the lifting plate 18 can drive the test tube to move when moving.
The working principle and the using process of the invention are as follows: when storing the reagent, the plug 13 is connected to a power supply to supply power to the reagent kit, the temperature in the reagent kit is in an effective temperature range of the prestored reagent by adjusting the thermostatic controller 8, the upper cover 1 of the casing is opened, the reagent is placed in the through hole 15 of the upper fixing frame 3, the bottom of the test tube enters the through hole 15 of the lower fixing frame 5 and is tightly attached to the waterproof membrane 6, the fixing springs 30 are arranged among the limiting plates 28, the fixing springs 30 can clamp the test tube in the middle of the limiting plates 28, the test tube can be driven to move when the lifting plate 18 moves, and finally the upper cover 1 of the casing is covered; when using the reagent, the upper cover 1 of the casing is opened, the threaded rod 20 is driven to rotate by the driving motor, the moving rings 21 at the two ends of the threaded rod 20 can keep moving in opposite directions, the lower end of the lifting rod 19 can be stretched by moving the position of the moving rings 21, so that the height of the lifting rod 19 can be adjusted, the height of the lifting plate 18 can be adjusted, the height of a test tube in the supporting frame 26 can be adjusted, a user can take the test tube out of the reagent box conveniently, when adjusting the height of the lifting rod 19, the sliding block 32 can be driven to slide in the sliding groove 31, when the sliding block 31 slides, the telescopic rod 33 and the buffer spring 34 can be extruded towards one end, the buffer effect can be achieved on the sliding block 32 by extruding the buffer spring 34, the condition that the height adjustment range of the test tube is too large can be effectively avoided, the inside rubber material that is of inoxidizing coating 36, can reduce the pressure that limiting plate 28 caused between to the test tube, avoid the test tube the condition of damage to appear, when shift ring 21 removes on threaded rod 20 surface, can drive spacing ring 23 and slide on gag lever post 22, thereby avoid shift ring 21 rotatory condition to appear, take out behind the required reagent, need close casing upper cover 1 immediately, through set up a plurality of visual windows 25 on the kit surface, can the person of facilitating the use observe the test tube condition in the reagent box.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (10)

1. An assessment gene group and a corresponding kit for gastric cancer prognosis prediction comprise a shell upper cover (1) and an upper fixing frame (3), and are characterized in that: the rear end of the upper surface of the upper cover (1) of the shell is rotatably connected with the rear surface of the shell (2) through a hinge (10), a constant temperature controller (8) is fixedly connected to the middle position of the lower end of the front surface of the shell (2), a through hole (15) is uniformly formed in the upper fixing frame (3), a lower fixing frame (5) is arranged under the upper fixing frame (3), the through hole (15) is uniformly formed in the lower fixing frame (5), a waterproof partition plate (7) is fixedly connected to one corner in the shell (2), a waterproof film (6) is arranged on the surface of a cavity formed by the lower fixing frame (5), the shell (2) and the waterproof partition plate (7), a harmless liquid (11) is filled in the waterproof film (6), and a compressor (9) is fixedly connected to the waterproof partition plate (7) and the shell (2) in the cavity, one corner of the right surface of the shell (2) is provided with a small hole, and a transmission line of the plug (13) penetrates through the small hole to be connected with the compressor (9).
2. The evaluation gene group for gastric cancer prognosis prediction and corresponding kit according to claim 1, wherein: the edge of the through hole (15) of the lower layer fixing frame (5) is provided with a concave waterproof membrane (6) which is filled with harmless liquid (11).
3. The evaluation gene group for gastric cancer prognosis prediction and corresponding kit according to claim 2, wherein: a label (14) is adhered to the center of the front surface of the housing (2).
4. The evaluation gene group for gastric cancer prognosis prediction and corresponding kit according to claim 3, wherein: four quadrant points of a through hole (15) in the upper fixing frame (3) are fixedly connected with rubber cushions (4), and the bottom end in the through hole (15) is provided with a protective cushion (35).
5. The evaluation gene group for gastric cancer prognosis prediction and corresponding kit according to claim 1, wherein: the upper surface of the shell upper cover (1) is fixedly connected with a handle (12).
6. The evaluation gene group for gastric cancer prognosis prediction and corresponding kit according to claim 5, wherein: the upper layer fixing frame (3) and the lower layer fixing frame (5) are clamped and connected inside the shell (2).
7. The evaluation gene group for gastric cancer prognosis prediction and corresponding kit according to claim 6, wherein: casing (2) outside surface is provided with visual window (25), the equal fixedly connected with connecting guide rail (16) in casing (2) inside both sides, two connecting guide rail (16) inboard equal sliding connection has link block (17), two fixedly connected with lifter plate (18), two in the middle of link block (17) equal fixed connection in support frame (26) side lifter plate (18), support frame (26) surface is provided with a plurality of connecting holes (37).
8. The evaluation gene group for gastric cancer prognosis prediction and corresponding kit according to claim 1, wherein: the utility model discloses a quick-witted, including casing (2), threaded rod (20), shift ring (21), lifter (19) other end rotation connection at sliding block (32) lower surface, the equal fixedly connected with dead lever (24) in shift ring (21) lower extreme both sides, dead lever (24) other end fixed connection is at spacing ring (23) side, spacing ring (23) sliding connection is inside spacing rod (22), the equal fixed connection in casing (2) side in spacing rod (22) both ends, threaded rod (20) both ends are all rotated and are connected at casing (2) side, threaded rod (20) one end transmission is connected with driving motor, threaded rod (20) both ends surface is provided with opposite direction screw thread, the equal threaded connection in threaded rod (20) both ends has shift ring (21), shift ring (21) upper surface rotation is connected with lifter (19), lifter (19) other end rotation is connected at sliding block (32) lower surface, the equal fixedly connected with dead lever (24) in spacing ring (23) side.
9. The evaluation gene group for gastric cancer prognosis prediction and corresponding kit according to claim 7, wherein: lifting plate (18) both sides all are provided with sliding tray (31), two sliding tray (31) inside equal sliding connection has sliding block (32), sliding block (32) one side fixedly connected with telescopic link (33), telescopic link (33) other end fixed connection is inboard in sliding tray (31), buffer spring (34) have been cup jointed on telescopic link (33) surface.
10. The evaluation gene group for gastric cancer prognosis prediction and corresponding kit according to claim 7, wherein: the supporting frame (26) upper surface both sides equal fixedly connected with sliding guide (27), two sliding guide (27) middle sliding connection has a plurality of limiting plate (28), limiting plate (28) surface all is provided with a plurality of spacing grooves (29), limiting plate (28) inboard surface is provided with inoxidizing coating (36), is provided with a plurality of fixed spring (30) in the middle of two relative limiting plate (28).
CN202110615720.9A 2021-06-02 2021-06-02 Evaluation gene group for gastric cancer prognosis prediction and corresponding kit Pending CN113264271A (en)

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CN202110615720.9A CN113264271A (en) 2021-06-02 2021-06-02 Evaluation gene group for gastric cancer prognosis prediction and corresponding kit

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Application Number Priority Date Filing Date Title
CN202110615720.9A CN113264271A (en) 2021-06-02 2021-06-02 Evaluation gene group for gastric cancer prognosis prediction and corresponding kit

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CN113264271A true CN113264271A (en) 2021-08-17

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Citations (10)

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