CN113262355B - Integrated piezoelectric driving intelligent insulin patch - Google Patents
Integrated piezoelectric driving intelligent insulin patch Download PDFInfo
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- CN113262355B CN113262355B CN202110575050.2A CN202110575050A CN113262355B CN 113262355 B CN113262355 B CN 113262355B CN 202110575050 A CN202110575050 A CN 202110575050A CN 113262355 B CN113262355 B CN 113262355B
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- insulin
- control unit
- program control
- piezoelectric
- liquid level
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses an integrated piezoelectric driving intelligent insulin patch, which comprises a program control unit, a piezoelectric micropump, an embedded needle and an insulin pump drug storage tube, wherein the components are arranged in a shell; wherein insulin pump stores up pencil, it includes: the device comprises a pipe body, a split-joint head and a follow-up sealant; the pipe body is coiled centripetally, and the split joint is connected with the pipe orifice at the inner side of the pipe body; the follow-up sealant is arranged at the tail part of the insulin in the tube body; a tracer ball is arranged in the follow-up sealant; the tube body is connected with the piezoelectric micropump pipeline through the splitting head; the burst amount of the liquid level detection device and the pulse burst number of the piezoelectric micropump are corrected by the program control unit. Compared with the prior art, the piezoelectric micropump adopted in the technical scheme has the advantages of small volume, no toxicity of pump body materials and environmental protection. The flow rate of the insulin medicine can be accurately controlled by changing the driving voltage; infusion precision is high, and stability is good, and the appearance is lighter and thinner.
Description
Technical Field
The invention belongs to the technical field of instruments for inputting media into a human body or inputting the media into the human body, and particularly relates to an integrated piezoelectric driving intelligent insulin patch.
Background
Diabetes is a group of metabolic diseases characterized by hyperglycemia. Hyperglycemia is caused by a defect in insulin secretion or an impaired biological action, or both. At present, the Chinese medicine becomes the third chronic disease after cardiovascular and cerebrovascular diseases and tumors, which seriously threatens human health. In the process of treating diabetes, continuous subcutaneous insulin injection, namely insulin pump treatment, is still the best choice for treating diabetes, the treatment mode is similar to providing an artificial pancreas for patients, simulates the function of the pancreas of people, and simulates the physiological secretion mode of healthy human insulin, namely secretion of basal rate, through a mode of intelligently and accurately quantitatively subcutaneously infusing insulin, so that the blood sugar content of the human body of the patients is regulated to control hyperglycemia, the phenomena of dawn phenomenon, dusk phenomenon and the like can be eliminated, blood sugar is effectively and stably controlled, the life quality of the users is improved, and the method has obvious advantages compared with the traditional treatment method.
The insulin pump that has disclosed at present mostly utilizes motor drive, and the mode of screw drive carries out the bolus of medicine, and this kind of drive and transmission mode are restricted by pitch, motor etc. and the structure is complicated, and insulin pump's bulk ratio is great, is difficult to miniaturize, and it is more troublesome and the cost is higher to change. Meanwhile, the insulin pump is separated from the embedded needle and is connected with the embedded needle through a transfusion tube, and the insulin pump is usually hung on the waist or placed in a pocket.
Disclosure of Invention
The invention aims to solve the problems that the existing insulin pump is large in size and troublesome to replace, the insulin pump and the embedded needle are separated, the insulin pump needs to be hung externally and the like, and the integrated piezoelectric driving intelligent insulin patch is provided;
insulin stores up pencil, it includes: a tube body 61, a coupling head 63, and a follow-up sealant 64; the pipe body 61 is coiled centripetally, and the split-joint head 63 is connected with the pipe orifice at the inner side of the pipe body 61; the follow-up sealant is arranged at the tail part of the insulin 65 in the tube body 61.
One end of the tube body 61 is provided with a narrow part 611, and one end of the narrow part 611 is provided with a tapered opening.
The follower sealant 64 is provided with a tracer ball 62.
A magnet 621 is arranged in the tracer ball 62.
Integral type piezoelectricity driven intelligent insulin pastes, it includes: the program control unit 1, the piezoelectric micropump 3, the embedded needle 5, the insulin drug storage tube 6, the shell 7 and the soft adhesive 8 are arranged in the shell 7;
the insulin drug storage tube 6 is the insulin drug storage tube of claim 4;
the piezoelectric micropump 3 and the embedded needle 5 are arranged in the middle of the program control unit 1; the tube body 61 is connected with the piezoelectric micropump 3 through a pipeline by a split joint 63; the program control unit 1 is electrically connected with the piezoelectric micropump 3; the amount of burst of the liquid level detection device 4 and the number of bursts of pulses of the piezoelectric micro-pump 3 are corrected by the amount of burst of the program control unit 1.
The program control unit 1 is internally provided with a wireless transmission module 2; the program control unit 1 is provided with a liquid level detection device 4; the tube body 61 is mounted on the liquid level detection device 4.
The liquid level detection device 4 is provided with a plurality of micro magnetic control switches 41, and the micro magnetic control switches 41 are arranged along the lower edge of the pipeline path.
The liquid level detection device 4 is provided with a plurality of micro magnetic control switches 41, and the micro magnetic control switches 41 are in contact with the lower edge of the tube body 61; the micro-magnetic switch 41 is triggered by a magnet 621.
The housing 7 comprises: a button shell chassis 71 and a button shell upper cover 72; the button shell chassis 71 is fixedly connected with the button shell upper cover 72 through a concave-convex seam allowance or a thread; the bottom end face of the button type shell chassis 71 is provided with a soft pasting glue 8.
The invention provides an integrated piezoelectric driving intelligent insulin patch, which comprises a program control unit, a piezoelectric micropump, an embedded needle and an insulin pump drug storage tube, wherein the components are arranged in a shell; wherein insulin pump stores up pencil, it includes: the device comprises a pipe body, a split-joint head and a follow-up sealant; the pipe body is coiled centripetally, and the split joint is connected with the pipe orifice at the inner side of the pipe body; the follow-up sealant is arranged at the tail part of the insulin in the tube body; a tracer ball is arranged in the follow-up sealant; the tube body is connected with the piezoelectric micropump pipeline through the splitting head; the burst amount of the liquid level detection device and the pulse burst number of the piezoelectric micropump are corrected by the program control unit. Compared with the prior art, the piezoelectric micropump adopted in the technical scheme has the advantages of small volume, no toxicity of pump body materials and environmental protection. The flow rate of the insulin medicine can be accurately controlled by changing the driving voltage; infusion precision is high, and stability is good, and the appearance is lighter and thinner.
Drawings
FIG. 1 is a schematic view of an insulin storage tube;
FIG. 2 is a schematic view of a portion of an insulin cartridge in cross-section;
FIG. 3 is a schematic view of the liquid level state of the insulin storage tube;
FIG. 4 is a schematic overall view of an integrated piezoelectrically-driven intelligent insulin patch;
FIG. 5 is a schematic view of an exploded structure of an integrated piezoelectric-driven intelligent insulin patch;
FIG. 6 is a schematic side view of the interior of the integrated piezoelectrically actuated smart insulin patch;
FIG. 7 is a block diagram of an integrated piezoelectrically actuated intelligent insulin patch; in the figure: the device comprises a program control unit 1, a processing unit 11, a battery 12, a wireless transmission module 2, a piezoelectric micropump 3, a medicine inlet 31, a medicine outlet 32, a liquid level detection device 4, a micro magnetic control switch 41, an embedded needle 5, a pintle 51, an insulin pump medicine storage tube 6, a tube body 61, a narrow part 611, a ventilation port 612, a tracer ball plug 62, a magnet 621, a separation and combination head 63, a follow-up sealant 64, insulin 65, a shell 7, a button shell chassis 71, a concave stopping port 711, a needle tube through hole 712, a button shell upper cover 72 and soft adhesive 8.
Detailed Description
Referring to fig. 1 to 7, an integrated piezoelectric-driven intelligent insulin patch includes: the system comprises a program control unit 1, a wireless transmission module 2, a piezoelectric micropump 3, a liquid level detection device 4, an embedded needle 5, an insulin pump drug storage tube 6, a shell 7 and a soft adhesive 8;
the program control unit 1 is respectively electrically connected with the wireless transmission module 2, the piezoelectric micropump 3 and the liquid level detection device 4; the insulin pump drug storage tube 6 is connected with the embedded needle 5 through a piezoelectric micropump 3;
the program control unit 1 comprises: the system comprises a processing unit 11 and a battery 12, wherein the processing unit 11 adopts an ARM series processor or an RISC series processor as a central processing unit of a main controller; the processing unit 11 is powered by a battery 12, and the battery 12 is a button battery;
the program control unit 1 is arranged on a C-shaped PCB which is arranged in the shell 7; the piezoelectric micropump 3 is arranged at the notch of the C-shaped PCB;
the program control unit 1 is also provided with a buzzer, and the buzzer warns and prompts the exhaustion of the insulin;
the wireless transmission module 2 is arranged in the PCB of the program control unit 1; the processing unit 11 is provided with a communication connecting end and a control signal output end, and the communication connecting end is connected with the wireless transmission module 2; the control signal output end is connected with the piezoelectric micropump 3;
the wireless transmission module 2 is a Bluetooth module or a wifi module, and the program control unit 1 is connected with the mobile terminal through the wireless transmission module 2; the mobile terminal checks through the APP or sets injection parameters; namely, the patient can set the injection amount and the injection time of the insulin in each day and each time by using the mobile phone APP, and can also be directly connected with the wireless transmission module 2 through the mobile phone; the infusion amount comprises a basic rate and a large pre-meal dose, the insulin amount secreted by a patient per day and per hour needs to be known firstly, the basic rate of the patient can be obtained by subtracting the insulin amount secreted by the patient per day and per hour from the insulin amount secreted by a healthy person per day and the large pre-meal dose is the insulin amount required by the patient per meal estimated in advance, the patient sets the infusion amount per day and per hour of the insulin through a mobile terminal APP, the information is transmitted to a program control unit through a wireless transmission module, and the patient can adjust the initially set infusion amount according to the actual condition, so that the intelligent infusion of the insulin is realized;
the piezoelectric micro pump 3 is a piezoelectric ceramic pump, and a medicine inlet 31 and a medicine outlet 32 are arranged on the piezoelectric micro pump 3; the length multiplied by the width multiplied by the height of the outline ruler of the piezoelectric micro pump 3 is less than 10mm multiplied by 2mm, and the output pressure is more than or equal to 80 KPa; the pulse number output by the processing unit 11 accurately controls the piezoelectric micropump to jet the insulin dosage, so that the high-precision insulin output is realized;
the liquid level detection device 4 is a liquid level detection plate, a plurality of micro magnetic control switches 41 are arranged on the liquid level detection device 4, and the micro magnetic control switches 41 are arranged along the lower edge of the pipeline path;
the liquid level detection device 4 is provided with a fixed lock catch which is in an inverted omega shape and is used for fixing the insulin pump medicine storage tube 6;
the embedded needle 5 is a medical indwelling needle, and the embedded needle 5 can be a straight needle or an inclined needle; the embedded needle 5 is provided with a pintle 51, and the pintle 51 is connected with the medicine outlet 32 on the piezoelectric micro pump 3 through a hose.
Insulin pump store up medicine pipe 6 be removable formula part, insulin pump stores up medicine pipe 6 and includes: the device comprises a pipe body 61, a tracing ball plug 62, a split-joint 63 and a follow-up sealant 64;
the tube body 61 is a tube for storing insulin, the tube body 61 is coiled centripetally, one end of the tube body 61 is provided with a narrow part 611, and one end of the narrow part 611 is provided with a conical opening; the other end of the tube body 61 is provided with a ventilation port 612; a magnet 621 is arranged in the tracing ball plug 62;
the tube body 61 is a transparent tube, and the tube body 61 resists elastic deformation pressure of more than 100 KPa;
the two sides of the split-joint head 63 are provided with butt joint needle tubes 631;
the dividing and combining head 63 is respectively butted with the tube body 61 and the medicine inlet 31 on the piezoelectric micro pump 3;
the follower sealant 64 is a viscous liquid that is not reactive with insulin, such as: silicone oil, glycerin and the like, wherein the follow-up sealant is arranged at the tail part of the insulin 65 in the tube body 61 to plug the insulin 65 to prevent backflow, evaporation and pollution by the external environment; the tracer ball 62 is in the follower sealant 64 or between the follower sealant 64 and the insulin 65.
Casing 7 be circular button type shell, casing 7 includes: a button shell chassis 71 and a button shell upper cover 72; a concave spigot 711 is arranged on the button shell chassis 71, a convex spigot is arranged in the button shell upper cover 72, and the button shell chassis 71 and the button shell upper cover 72 are locked and connected through the concave spigot or the thread; the PCB is arranged in the button type shell chassis 71;
the top of the button shell upper cover 72 is provided with a transparent visual window, and the position of the tracer ball plug 62 in the pipe body 61 can be seen through the button shell upper cover 72;
the middle part of the button type shell chassis 71 is provided with a needle tube through hole 712, and the inner side of the needle tube through hole 712 is provided with a pintle fixing part; the pintle holding part holds the pintle 51 of the embedded needle 5;
the PCB provided with the program control unit 1 is C-shaped, and the C-shaped PCB is arranged in the button type shell chassis 71; the piezoelectric micropump 3 is arranged at the notch of the C-shaped PCB.
The liquid level detection device 4 is sleeved on the program control unit 1, the pipe body 61 is spirally fixed on the liquid level detection device 4, and the plurality of micro magnetic control switches 41 are in contact with the lower edge of the pipe body 61;
the liquid level detection device 4 is electrically connected with the program control unit 1, and the tracer ball plug 62 moves to different positions to trigger the micro magnetic control switch 41 at the corresponding position; the tracer ball plug 62 realizes the monitoring of the insulin injection amount by triggering the micro magnetic control switches 41 at different positions; the amount of burst of the liquid level detection device 4 and the number of bursts of pulses of the piezoelectric micro-pump 3 are corrected by the amount of burst of the program control unit 1.
When the insulin in the tube body 61 is used up, the tracing ball plug 62 is wedged tightly with the conical opening at one end of the narrow part 611; the piezoelectric micropump 3 generates reactive power, the micro magnetic control switch 41 at the position of the tracer ball plug 62 has no displacement change, a warning prompt is triggered, the program control unit can give an alarm and give a prompt to the APP on the mobile terminal through the wireless transmission module 2, so that the patient is reminded that the insulin in the tube body 61 is used up;
the bottom end face of the button type shell chassis 71 is provided with a pasting soft glue 8, and the bottom end face of the pasting soft glue 7 is provided with an adhesive; the button type shell chassis 71 is pasted on the skin of the injection position of the user through pasting soft glue 8;
the soft pasting glue 8 is made of a skin-friendly material, such as non-woven fabric, an anti-pollution pasting film or an anti-infection perforated pasting tape, the upper surface of the soft pasting glue 8 is fixed to the lower surface of the button type shell chassis 71 through glue, the lower surface of the soft pasting glue 8 is also provided with one layer of glue and one layer of film, and when being pasted by a patient, the film is torn down, so that the whole integrated insulin pump can be pasted at the position where the patient injects insulin.
Integral type piezoelectricity driven intelligence insulin pastes, and embedded needle 5 in integral type piezoelectricity driven intelligence insulin pastes can adopt the oblique needle to apply at patient's belly, and the insulin quantity can be looked over at any time to APP on the mobile terminal, and the APP on the mobile terminal still can make the suggestion when the insulin in the body 61 is used up, opens button casing upper cover 72, can change piezoelectricity micropump 3, embedded needle 5 and insulin pump storage medicine pipe 6.
The embodiments of the present invention are described in order to facilitate those skilled in the art to understand and apply the present invention, and the present invention is only an optimized embodiment or a preferred embodiment, so the present invention is not limited to the description of the embodiment. If the related technical personnel make equivalent structural changes or various modifications without creative efforts while adhering to the basic technical solution of the present invention, the protection scope of the present invention is covered.
Claims (6)
1. Insulin stores up pencil, its characterized in that: it includes: a tube body (61), a coupling head (63), and a follow-up sealant (64); the pipe body (61) is coiled centripetally, and the opening and closing head (63) is connected with an inner pipe orifice at the front end of the pipe body (61); the follow-up sealant is arranged at the tail part of the insulin (65) in the tube body (61);
one end of the pipe body (61) is provided with a narrow part (611), and one end of the narrow part (611) is provided with a conical opening;
a tracer ball (62) is arranged in the follow-up sealant (64);
a magnet (621) is arranged in the tracer ball (62).
2. Integral type piezoelectricity drive intelligence insulin pastes, its characterized in that: it includes: the medical device comprises a program control unit (1), a piezoelectric micropump (3), an embedded needle (5), an insulin drug storage tube (6), a shell (7) and a paste soft adhesive (8), wherein the program control unit (1), the piezoelectric micropump (3), the embedded needle (5) and the insulin drug storage tube (6) are arranged in the shell (7);
the insulin drug storage tube (6) is the insulin drug storage tube of claim 1;
the piezoelectric micropump (3) and the embedded needle (5) are arranged in the middle of the program control unit (1); the tube body (61) is connected with the piezoelectric micropump (3) through a split joint (63) by a pipeline; the program control unit (1) is electrically connected with the piezoelectric micropump (3); the amount of burst of the liquid level detection device (4) and the number of pulses of the piezoelectric micropump (3) are corrected by the amount of burst of the program control unit (1).
3. The integrated piezoelectric driven intelligent insulin patch according to claim 2, wherein: a wireless transmission module (2) is arranged in the program control unit (1); a liquid level detection device (4) is arranged on the program control unit (1); the tube body (61) is arranged on the liquid level detection device (4).
4. The integrated piezoelectric driven intelligent insulin patch according to claim 3, wherein: the liquid level detection device (4) is provided with a plurality of micro magnetic control switches (41), and the micro magnetic control switches (41) are arranged along the lower edge of the pipeline path.
5. The integrated piezoelectric driven intelligent insulin patch according to claim 4, wherein: the liquid level detection device (4) is provided with a plurality of micro magnetic control switches (41), and the micro magnetic control switches (41) are in contact with the lower edge of the pipe body (61); the micro magnetic control switch (41) is triggered by a magnet (621).
6. The integrated piezoelectric driven intelligent insulin patch according to claim 5, wherein: the housing (7) comprises: a button shell chassis (71) and a button shell upper cover (72); the button shell chassis (71) is in locking connection with the button shell upper cover (72) through a concave-convex spigot or a thread; the bottom end face of the button-type shell chassis (71) is provided with a soft adhesive (8).
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| CN202110575050.2A CN113262355B (en) | 2021-05-25 | 2021-05-25 | Integrated piezoelectric driving intelligent insulin patch |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202110575050.2A CN113262355B (en) | 2021-05-25 | 2021-05-25 | Integrated piezoelectric driving intelligent insulin patch |
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| CN113262355A CN113262355A (en) | 2021-08-17 |
| CN113262355B true CN113262355B (en) | 2022-02-15 |
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Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4313439A (en) * | 1980-03-24 | 1982-02-02 | Biotek, Inc. | Automated, spring-powered medicament infusion system |
| US4525164A (en) * | 1981-04-24 | 1985-06-25 | Biotek, Inc. | Wearable medication infusion system with arcuated reservoir |
| CN87206539U (en) * | 1987-04-16 | 1988-06-22 | 吉林市计量科学技术研究所 | Magneto-optical monitor for liquid level |
| US6554521B1 (en) * | 1999-09-14 | 2003-04-29 | Sakura Color Products Corporation | Applicator |
| EP2879741B1 (en) * | 2012-07-31 | 2021-04-28 | Nipro Healthcare Systems, LLC | Device and method for dispensing fluid from an infusion pump |
| WO2014156857A1 (en) * | 2013-03-27 | 2014-10-02 | 株式会社サクラクレパス | Applicator |
| CN103599578B (en) * | 2013-12-03 | 2015-08-05 | 吉林大学 | A kind of handheld piezoelectric drives insulin pump |
| CN109321035A (en) * | 2017-07-27 | 2019-02-12 | 刘兴丹 | A kind of multilayer ink neutrality pen core |
| CN107469185A (en) * | 2017-09-15 | 2017-12-15 | 金明必 | Pump transfusion means for insulin and the portable mini docile type insulin pump with this device |
| CN111376608A (en) * | 2018-12-29 | 2020-07-07 | 北京梦之墨科技有限公司 | Ink box and ink box system |
| CN210611023U (en) * | 2019-09-24 | 2020-05-26 | 北京如翼信息技术有限公司 | Follow-up sealing oil leakage prevention electronic cigarette cartridge structure |
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- 2021-05-25 CN CN202110575050.2A patent/CN113262355B/en active Active
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Effective date of registration: 20220831 Address after: Room 1201-1210, South Building, Huiyan building, Changzhou science and Education City, No.18, middle Changwu Road, Wujin District, Changzhou City, Jiangsu Province, 213164 Patentee after: Jiangsu GaoKai precision fluid technology Co.,Ltd. Address before: 130025 No. 5988 Renmin Street, Nanguan District, Jilin, Changchun Patentee before: Jilin University |
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