CN113244659A - Separation and extraction device for animal blood - Google Patents

Separation and extraction device for animal blood Download PDF

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Publication number
CN113244659A
CN113244659A CN202110715827.0A CN202110715827A CN113244659A CN 113244659 A CN113244659 A CN 113244659A CN 202110715827 A CN202110715827 A CN 202110715827A CN 113244659 A CN113244659 A CN 113244659A
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CN
China
Prior art keywords
driving structure
detection element
animal blood
transparent container
suction pipe
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Pending
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CN202110715827.0A
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Chinese (zh)
Inventor
唐琪
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Qingyuan Taisheng Biotechnology Co ltd
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Qingyuan Taisheng Biotechnology Co ltd
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Priority to CN202110715827.0A priority Critical patent/CN113244659A/en
Publication of CN113244659A publication Critical patent/CN113244659A/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D17/00Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/02Separation of non-miscible liquids
    • B01D17/0208Separation of non-miscible liquids by sedimentation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D17/00Separation of liquids, not provided for elsewhere, e.g. by thermal diffusion
    • B01D17/12Auxiliary equipment particularly adapted for use with liquid-separating apparatus, e.g. control circuits

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  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention provides a separation and extraction device for animal blood, and relates to the field of blood separation. The separation and extraction device for the animal blood comprises a machine shell, a transparent container, an extraction mechanism and a circuit main board, wherein the transparent container is positioned and installed in an accommodating cavity of the machine shell, and the extraction mechanism comprises a driving structure, a detection element, an absorption pipe, a negative pressure absorption pump and a communication pipeline for connecting the absorption pipe and the negative pressure absorption pump; the detection element and the suction pipe are respectively in transmission connection with the driving structure, the detection element and the suction pipe are arranged at intervals, and the detection height of the detection element and the pipe orifice at the lower end of the suction pipe are positioned on the same horizontal plane, so that the suction pipe can suck the layering liquid in the transparent container, and the detection element can detect the components of the layering liquid outside the transparent container; detection component, drive structure, negative pressure suction pump are connected with the circuit mainboard electricity respectively, and detection component is used for sending the composition detection signal of layering liquid to the circuit mainboard, and the circuit mainboard receives detection signal and control drive structure and open and stop, draws operation reliability and efficiency higher.

Description

Separation and extraction device for animal blood
Technical Field
The invention relates to the technical field of blood separation, in particular to a separation and extraction device for animal blood.
Background
The pig blood protein powder is a nutriment prepared by separating, concentrating and drying blood, wherein the blood can be separated into plasma at the upper layer, red blood cells at the lower layer and white blood cells and platelets at the middle layer, the plasma can be used for preparing plasma protein powder, and the rest components can be used for preparing blood cell protein powder.
A conventional patent discloses a blood component separation apparatus including a first container, a second container and a third container which are connected in this order, the first container being a container for separating blood into a plasma leukocyte mixed layer and a blood cell layer, the second container being a container for storing the plasma leukocyte mixed layer and centrifugally separating the same into a plasma layer and a leukocyte layer, the plasma layer being sent to the first container for storage, and the leukocyte layer being sent to the third container for storage. Wherein, the first catheter is provided with a first three-way joint for adding reaction liquid to stratify blood; the second conduit is provided with a second three-way joint for adding the frozen stock solution to preserve the blood sample; the fifth conduit is provided with a third three-way joint for the needle of the syringe to extend into to draw the sample.
In the prior art, the blood after layering is extracted manually, because the plasma layer is faint yellow, the middle layer is white and opaque, and the red cells are dark red and opaque, the color appearance of each component can not be visually observed manually, the plasma component can not be fully extracted, other blood components can not be mixed, and the extraction operation reliability and efficiency are low.
Disclosure of Invention
In order to solve the above problems, an object of the present invention is to provide an apparatus for separating and extracting animal blood, which solves the problems that sufficient extraction of plasma components is not ensured and other blood components are not mixed by manually observing the color appearance of each component, and the reliability and efficiency of extraction operation are low.
The technical scheme of the device for separating and extracting the animal blood comprises the following steps:
the separation and extraction device for the animal blood comprises a machine shell, a transparent container, an extraction mechanism and a circuit main board, wherein a containing cavity is formed in the machine shell, the transparent container is positioned and installed in the containing cavity, and the extraction mechanism comprises a driving structure, a detection element, an absorption pipe, a negative pressure absorption pump and a communication pipeline for connecting the absorption pipe and the negative pressure absorption pump;
the detection element and the suction pipe are respectively in transmission connection with the driving structure, the detection element and the suction pipe are arranged at intervals, the detection height of the detection element and the lower end pipe orifice of the suction pipe are positioned on the same horizontal plane, so that the suction pipe sucks the layered liquid in the transparent container, and the detection element detects the components of the layered liquid outside the transparent container;
the detection element, the driving structure and the negative pressure suction pump are electrically connected with the circuit main board respectively.
Further, the drive structure is gone up the transmission and is installed the support of falling L shape, the support of falling L shape includes fixed connection's horizontal branch and vertical branch, the detecting element is fixed the lower extreme of vertical branch, the suction tube is installed horizontal branch's overhang end.
Furthermore, the driving structure is a screw nut driving structure and comprises a vertical guide rail, a sliding block, a motor, a screw rod and a nut, the sliding block is installed on the vertical guide rail in a guiding mode, the nut is fixedly installed on the sliding block, the nut is in threaded fit with the screw rod, the motor is in transmission connection with the screw rod, and the inverted L-shaped support is fixed on the sliding block.
Furthermore, the detection element is a turbidity sensor, and a turbidity threshold value is preset on the circuit board, so that when the turbidity value detected by the turbidity sensor exceeds the turbidity threshold value, the circuit board controls the driving structure to stop.
Further, the turbidity threshold is any value between 10ppm and 50 ppm.
Further, the turbidity threshold is any value between 15ppm and 30 ppm.
Furthermore, a sealing plug is fixed on the lower portion of the suction pipe, the lower side face of the sealing plug is arranged close to the pipe orifice at the lower end of the suction pipe, and the sealing plug is in sliding sealing fit with the inner wall of the transparent container.
Furthermore, the vertical distance between the lower side surface of the sealing plug and the lower end pipe orifice of the suction pipe is any value from 2mm to 5 mm.
Furthermore, the driving structure is a gear and rack driving structure and comprises a vertical guide rail, a sliding block, a motor, a rack and a gear, the sliding block is installed on the vertical guide rail in a guiding mode, the motor is fixedly installed on the sliding block and is in transmission connection with the gear, the rack is in meshing fit with the gear, and the inverted L-shaped support is fixed on the sliding block.
Has the advantages that: this separation extraction element of animal blood has adopted the casing, transparent container, extract the structural design of mechanism and circuit board, wherein, it includes the drive structure to extract the mechanism, the detection component, the suction tube, negative pressure suction pump and intercommunication pipeline, drive the detection component through the drive structure, the suction tube reciprocates, because detection component and suction tube interval arrangement, and the detection height of detection component is located same horizontal plane with the lower extreme mouth of pipe of suction tube, the detection component can be in the composition of transparent container's outside detection layering liquid, and the suction tube then absorbs the layering liquid of corresponding height in transparent container.
The upper layer of plasma is sucked and close to the middle leucocyte and platelet layer, the turbidity of the middle stratified fluid is obviously increased compared with that of the plasma, namely, the stratified fluid component at the height is no longer the plasma, so that the driving structure is controlled to stop working in time, and the sucking tube does not suck the stratified fluid at the lower part. Compared with the prior art, the color appearance of each component is manually observed, the plasma component can be fully extracted without mixing other blood components, and the extraction operation reliability and efficiency are higher.
Drawings
Fig. 1 is a schematic structural view of an animal blood separation and extraction device according to embodiment 1 of the present invention;
FIG. 2 is a schematic view showing the structure of an apparatus for separating and extracting animal blood according to embodiment 1 of the present invention (in an initial operation state);
fig. 3 is a schematic circuit diagram of the apparatus for separating and extracting animal blood according to embodiment 1 of the present invention.
In the figure: the device comprises a machine shell 1, a positioning clamping seat 10, a transparent container 2, an extraction mechanism 3, a screw and nut driving structure 30, a vertical guide rail 300, a sliding block 301, a motor 302, a screw rod 303, a nut 304, a turbidity sensor 31, a suction pipe 32, a negative pressure suction pump 33, a communication pipeline 34, a sealing plug 35, a 4-inverted L-shaped support, a horizontal support rod 41 and a vertical support rod 42.
Detailed Description
The following detailed description of embodiments of the present invention is provided in connection with the accompanying drawings and examples. The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.
In embodiment 1 of the apparatus for separating and extracting animal blood of the present invention, as shown in fig. 1 to 3, the apparatus for separating and extracting animal blood includes a casing 1, a transparent container 2, an extraction mechanism 3 and a circuit board, wherein an accommodating cavity is formed inside the casing 1, the transparent container is positioned and mounted on a positioning card seat 10 in the accommodating cavity, and the extraction mechanism 3 includes a driving structure, a detecting element, an absorption tube 32, a negative pressure suction pump 33 and a communication pipeline 34 connecting the absorption tube 32 and the negative pressure suction pump 33; the detection element and the suction pipe 32 are respectively in transmission connection with the driving structure, the detection element and the suction pipe 32 are arranged at intervals, and the detection height of the detection element and the lower end pipe orifice of the suction pipe 32 are positioned on the same horizontal plane, so that the suction pipe 32 sucks the layering liquid in the transparent container 2, and the detection element detects the composition of the layering liquid outside the transparent container 2; the detection element, the driving structure and the negative pressure suction pump 33 are respectively electrically connected with the circuit main board, the detection element is used for sending component detection signals of the layering liquid to the circuit main board, and the circuit main board receives the detection signals and controls the driving structure to start and stop.
This separation extraction element of animal blood has adopted casing 1, transparent container 2, the structural design who draws mechanism 3 and circuit board, wherein, it includes the drive structure to draw mechanism 3, detecting element, suction tube 32, negative pressure suction pump 33 and communicating pipe 34, drive detecting element through the drive structure, suction tube 32 reciprocates, because detecting element and suction tube 32 interval arrangement, and detecting element's the lower extreme mouth of pipe that detects height and suction tube 32 is located same horizontal plane, detecting element can be at the composition of transparent container 2's outside detection layering liquid, and suction tube 32 then absorbs the layering liquid of corresponding height in transparent container 2.
The upper plasma layer is drawn and close to the middle leukocyte and platelet layer, and the turbidity of the middle stratified fluid is significantly increased compared to that of the plasma, that is, the high stratified fluid component is no longer plasma, so that the driving mechanism is controlled to stop working in time, and the drawing tube 32 no longer draws the lower stratified fluid. Compared with the prior art, the color appearance of each component is manually observed, the plasma component can be fully extracted without mixing other blood components, and the extraction operation reliability and efficiency are higher.
In this embodiment, the driving structure is mounted with an inverted L-shaped bracket 4 in a transmission manner, the inverted L-shaped bracket 4 comprises a horizontal strut 41 and a vertical strut 42 which are fixedly connected, the detecting element is fixed at the lower end of the vertical strut 42 of the inverted L-shaped bracket 4, and the suction pipe 32 is mounted at the overhanging end of the horizontal strut 41 of the inverted L-shaped bracket 4. Make detecting element and suction tube 32 interval distribution through falling L shape support 4, detecting element's mounted position is in suction tube 32's lower extreme mouth of pipe department, utilizes to survey highly parallel and level with the imbibition, guarantees the composition that can real-time detection intake layering liquid.
The driving structure is a screw nut driving structure 30, which comprises a vertical guide rail 300, a sliding block 301, a motor 302, a screw rod 303 and a nut 304, wherein the sliding block 301 is installed on the vertical guide rail 300 in a guiding manner, the nut 304 is fixedly installed on the sliding block 301, the nut 304 is in threaded fit with the screw rod 303, the motor 302 is in transmission connection with the screw rod 303, and the inverted L-shaped support 4 is fixed on the sliding block 301. The motor 302 works to drive the screw rod 303 to rotate, and the screw rod 303 is in threaded fit with the nut 304 to drive the nut 304 and the slide block 301 to move up and down in a translation manner along the vertical guide rail 300; correspondingly, the inverted L-shaped bracket 4, the detection element and the suction pipe 32 all generate up-and-down translation motion, the driving precision of the screw nut driving structure 30 is high, and the detection element and the suction pipe 32 can be accurately and stably driven to move for sucking liquid.
Moreover, the detection element is a turbidity sensor 31, and a turbidity threshold value is preset on the circuit board, so that when the turbidity value detected by the turbidity sensor 31 exceeds the turbidity threshold value, the circuit board controls the driving structure to stop. Wherein, the turbidity threshold value of the circuit main board is any value between 10ppm and 50ppm, and further, the turbidity threshold value is any value between 15ppm and 30 ppm.
Specifically, the turbidity sensor 31 is CG-34 in model, and the working principle is that suspended matters in water scatter light, and the turbidity value of the water is calculated by measuring the scattered light intensity in the direction perpendicular to the incident light and comparing the scattered light intensity with an internal calibration value; the preset turbidity threshold value on the circuit main board is 20ppm, because the transparency of the separated upper layer plasma is good, if the detected turbidity value is less than 20ppm, the circuit main board is indicated as a plasma layer, and once the detected turbidity value exceeds 20ppm, the circuit main board indicates that leucocyte and platelet layers are detected, so that the driving structure is controlled to stop moving downwards, and other components of blood are prevented from being extracted.
In addition, a sealing plug 35 is fixed on the lower part of the suction pipe 32, the lower side surface of the sealing plug 35 is arranged close to the lower end pipe opening of the suction pipe 32, and the sealing plug 35 is in sliding sealing fit with the inner wall of the transparent container 3. And the vertical distance between the lower side surface of the sealing plug 35 and the lower end pipe orifice of the suction pipe 32 is any value between 2mm and 5 mm. Specifically, the vertical interval between the downside of sealing plug 35 and the lower extreme mouth of pipe of suction tube 32 is 2mm, and sealing plug 35 can play the effect of scraping attached plasma to the inner wall of transparent container 3, moreover, plays the extrusion effect downwards through sealing plug 35 to the blood after the separation, makes the plasma of layering can be pumped and draw by fully pumping.
In order to meet different use requirements, the driving structure can be designed into a gear and rack driving structure which comprises a vertical guide rail, a sliding block, a motor, a rack and a gear, wherein the sliding block is installed on the vertical guide rail in a guiding mode, the motor is fixedly installed on the sliding block, the motor is in transmission connection with the gear, the rack is in meshing fit with the gear, the length of the rack is parallel to the extending direction of the vertical guide rail, and an inverted L-shaped support is fixed on the sliding block. The motor works to drive the gear to rotate, and the rack is meshed with the gear to move along the extending direction of the rack, so that the sliding block, the inverted L-shaped support, the detection element and the suction pipe are driven to move up and down to suck the layering liquid with corresponding height.
The above description is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and substitutions can be made without departing from the technical principle of the present invention, and these modifications and substitutions should also be regarded as the protection scope of the present invention.

Claims (9)

1. A separation and extraction device for animal blood is characterized by comprising a machine shell, a transparent container, an extraction mechanism and a circuit board, wherein a containing cavity is arranged inside the machine shell, the transparent container is positioned and installed in the containing cavity, and the extraction mechanism comprises a driving structure, a detection element, an absorption pipe, a negative pressure absorption pump and a communication pipeline for connecting the absorption pipe and the negative pressure absorption pump;
the detection element and the suction pipe are respectively in transmission connection with the driving structure, the detection element and the suction pipe are arranged at intervals, the detection height of the detection element and the lower end pipe orifice of the suction pipe are positioned on the same horizontal plane, so that the suction pipe sucks the layered liquid in the transparent container, and the detection element detects the components of the layered liquid outside the transparent container;
the detection element, the driving structure and the negative pressure suction pump are electrically connected with the circuit main board respectively.
2. The device for separating and extracting animal blood as claimed in claim 1, wherein the driving structure is provided with an inverted L-shaped bracket in a transmission way, the inverted L-shaped bracket comprises a horizontal supporting rod and a vertical supporting rod which are fixedly connected, the detecting element is fixed at the lower end of the vertical supporting rod, and the suction pipe is arranged at the overhanging end of the horizontal supporting rod.
3. The device for separating and extracting animal blood as claimed in claim 2, wherein the driving structure is a screw nut driving structure, which comprises a vertical guide rail, a slide block, a motor, a screw rod and a nut, the slide block is guided and mounted on the vertical guide rail, the nut is fixedly mounted on the slide block, the nut is in threaded fit with the screw rod, the motor is in transmission connection with the screw rod, and the inverted L-shaped bracket is fixed on the slide block.
4. The device for separating and extracting animal blood according to claim 1, wherein the detecting element is a turbidity sensor, and a turbidity threshold value is preset on the circuit board, so that when the turbidity value detected by the turbidity sensor exceeds the turbidity threshold value, the circuit board controls the driving structure to stop.
5. The device for separating and extracting animal blood as claimed in claim 4, wherein the turbidity threshold is any value between 10ppm and 50 ppm.
6. The device for separating and extracting animal blood as claimed in claim 4, wherein the turbidity threshold is any value between 15ppm and 30 ppm.
7. The animal blood separating and extracting device as claimed in claim 1, wherein a sealing plug is further fixed to the lower portion of the suction tube, the lower side surface of the sealing plug is arranged close to the lower end opening of the suction tube, and the sealing plug is in sliding sealing fit with the inner wall of the transparent container.
8. The animal blood separating and extracting device according to claim 7, wherein the vertical distance between the lower side surface of the sealing plug and the lower end opening of the suction tube is any value between 2mm and 5 mm.
9. The device for separating and extracting animal blood as claimed in claim 2, wherein the driving structure is a rack-and-pinion driving structure, which comprises a vertical guide rail, a slide block, a motor, a rack and a pinion, the slide block is guided and mounted on the vertical guide rail, the motor is fixedly mounted on the slide block, the motor is in transmission connection with the pinion, the rack is engaged and matched with the pinion, and the inverted L-shaped bracket is fixed on the slide block.
CN202110715827.0A 2021-06-24 2021-06-24 Separation and extraction device for animal blood Pending CN113244659A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110715827.0A CN113244659A (en) 2021-06-24 2021-06-24 Separation and extraction device for animal blood

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110715827.0A CN113244659A (en) 2021-06-24 2021-06-24 Separation and extraction device for animal blood

Publications (1)

Publication Number Publication Date
CN113244659A true CN113244659A (en) 2021-08-13

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Application Number Title Priority Date Filing Date
CN202110715827.0A Pending CN113244659A (en) 2021-06-24 2021-06-24 Separation and extraction device for animal blood

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114768300A (en) * 2022-04-22 2022-07-22 正大制药(青岛)有限公司 Preparation method for paricalcitol production

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114768300A (en) * 2022-04-22 2022-07-22 正大制药(青岛)有限公司 Preparation method for paricalcitol production

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