CN113243312B - A cylinder device that is used for automatic controllable lift platform of behavioural experiment - Google Patents
A cylinder device that is used for automatic controllable lift platform of behavioural experiment Download PDFInfo
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- CN113243312B CN113243312B CN202110385788.2A CN202110385788A CN113243312B CN 113243312 B CN113243312 B CN 113243312B CN 202110385788 A CN202110385788 A CN 202110385788A CN 113243312 B CN113243312 B CN 113243312B
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- flat plate
- circular flat
- cylindrical container
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K29/00—Other apparatus for animal husbandry
- A01K29/005—Monitoring or measuring activity, e.g. detecting heat or mating
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/02—Breeding vertebrates
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
Abstract
The invention belongs to the technical field of biological experiments, and particularly relates to a cylindrical device of an automatic controllable lifting platform for a behavioral experiment. The device consists of a basic bracket, a cylindrical container, a circular flat plate, a motor, a transmission mechanism driven by the motor and a computer automatic control system; during experiment, water is contained in the cylindrical container, and the experimental animal is placed on the circular flat plate; the computer automatic control system controls the motor to drive the transmission mechanism, so that the circular flat plate in the cylindrical container rises and falls, and the animals are placed in the water body or leave the water body; these operations are repeated according to design requirements. The experimental animal can complete the non-evasive, discontinuous and repeated swimming experience for a plurality of times; the experience represents a unique experimental animal behavior, such that the behavior comprises the transition from just resistant behavior to gradually non-resistant behavior at a later time, providing a reliable experimental animal model for the in-depth exploration of the neurobiological mechanisms behind this unique behavior.
Description
Technical Field
The invention belongs to the technical field of biological experiments, and particularly relates to an experimental device for detecting animal abandon sample behaviors.
Background
The inescapable, discrete, repeated unpleasant experience is important to the development of disclaimer behavior, as a student who is difficult to learn math may be because he is given a second and a third hit in math to eventually disclaimer learning math, but such disclaimers do not affect his learning of other disciplines. Relinquishing behavior is very important for living creatures. In daily life, we often face some uncontrollable unpleasant experiences. During this time, we must make a decision: continue to resist in vain or abandon things before the eye to do something more fruitful; abandonment is one of the important activities in personal life. On the one hand, premature and repeated abstinence may lead to the loss of self-esteem of the individual, which in turn may lead to depression; on the other hand, the lack of timely and judicious abandonment results in a significant waste of energy, time, and resources, which may also result in remorseness/shame and depression, which in turn translates into depression. Therefore, timely/judicious abandonment plays a crucial role in human survival.
To date, the study on abandonment is almost blank internationally, and it is desired to explore the neurobiological mechanism of abandonment, wherein the biggest challenge is the lack of experimental devices that can perfectly simulate the behavior of giving up the abandonment, and such devices should have the following characteristics: the experimental animals were able to complete an inescapable, discrete, repeated unpleasant experience during the course of the experiment. The experimental device has the characteristics of perfectly fitting the requirements, the round flat plate which can be controlled to lift realizes the non-evasive, discontinuous and repeated swimming experience on the experimental animal, and the swimming is unpleasant for the experimental animal. The device can continuously observe that the experimental animal continuously struggles resistance in water from beginning after going through the swimming experience which cannot escape again and again until the behavior state of the experimental animal is changed to give up resistance later.
Disclosure of Invention
The invention aims to provide a cylinder device of an automatic controllable lifting platform for a behavioural experiment, which has the advantages of simple structure, convenient operation and excellent effect.
The invention relates to a cylinder device of an automatic controllable lifting platform for a behavioural experiment, aiming at enabling an experimental animal to complete an inescapable, discontinuous and repeated swimming experience for many times, wherein the experience embodies a unique and brand-new experimental animal behavioural method and researches a neurobiological mechanism of animal abandoning behaviors according to the experience.
The invention relates to a cylinder device of an automatic controllable lifting platform for a behavioural experiment, which consists of a basic bracket, a cylinder container, a circular flat plate, an electric mechanism and a computer automatic control system; wherein:
the primary support, comprising: the square base is provided with two vertical rectangular supporting plates at diagonal positions of the square base, and the rectangular supporting plates are fixedly connected with the tops of the two vertical rectangular supporting plates and are parallel to the base;
the cylindrical container is used for containing experimental water; the square base is placed at the center of the square base;
the circular flat plate is positioned in the cylindrical container, and a gap is formed between the circular flat plate and the inner wall of the cylindrical container; the round flat plate is used for placing experimental animals;
the center of the square base, the center of the cylindrical container and the center of the circular flat plate are positioned on a straight line vertical to the base;
the motor mechanism comprises a motor and a transmission mechanism driven by the motor; the transmission mechanism is used for pulling the circular flat plate in the cylindrical container to lift up and down; specifically, the motor is arranged on a rectangular support plate parallel to the base; the transmission mechanism comprises a cylindrical sleeve and a cylindrical traction rod arranged in the cylindrical sleeve; the lower end of the cylindrical traction rod is connected with the circular flat plate;
the computer automation control system comprises an environment control connecting plate, an integrated control acquisition box and a computer; wherein, the computer transmits control signal to integrated control collection box, environmental control connecting plate in proper order to control electric work, thereby drive mechanism realizes that the circular flat board of cylinder container inside rises and descends.
The device of the invention can lead the experimental animal to complete the non-evasive, discontinuous and repeated swimming experience for a plurality of times through the circular flat plate which can be controlled to lift. The method comprises the following specific operations: firstly, a circular flat plate is arranged at the higher position of a cylindrical container, a proper amount of water is injected into the cylindrical container, and then the experimental animal is placed on the circular flat plate; when the experiment animal is needed, the computer automatic control system controls the motor mechanism to pull the circular flat plate to gradually descend until the experiment animal falls into the water and stays in the water for a period of time (such as 15 seconds), and then the computer automatic control system controls the motor mechanism to pull the circular flat plate to gradually ascend so that the experiment animal leaves the water body.
The above operation process is repeated according to design requirements.
Such behaviors include a transition from just-beginning resistant behavior to later increasingly less resistant behavior, providing a reliable experimental animal model for the in-depth exploration of the neurobiological mechanisms behind this unique and novel behavior.
Compared with the prior art (a cylindrical container for forced swimming experiments), the invention has the following main advantages:
firstly, the round flat plate capable of lifting in the invention has novel conception. The computer automatic system controls the electric mechanism to realize ascending and descending at any time, and the experimental animal realizes the non-evasive, discontinuous and repeated swimming experience by applying a simple mechanical principle, thereby realizing the purpose of creating the abandoning behavior animal model.
Secondly, the invention has a plurality of experimental functions and purposes. When the circular flat plate is dragged or pushed to ascend or descend, the invention can be used for detecting abandoned behavior induced by non-evasive, discontinuous and repeated swimming experiences or can be used for exploring a dynamic state change before depression-like behavior is formed; the invention can be used in conventional forced swimming experiments to test depression-like behavior or stress-related animal models when the circular plate is in the lowest position and is immobile.
Thirdly, the invention has strong practicability and operability. The lifting device is very simple to use, and the circular flat plate can be conveniently lifted or lowered by controlling the electric mechanism through the computer automatic control system.
Fourthly, the invention has reasonable structure, easy manufacture and low cost.
Drawings
FIG. 1 is a schematic diagram of the structure of the experimental apparatus of the present invention.
FIG. 2 is a top view of the experimental set-up of the present invention.
Fig. 3 is a diagram of a computer automated control system.
FIG. 4 is a right side view of the experimental apparatus of the present invention.
FIG. 5 is a schematic view of the driving mechanism of the experimental apparatus of the present invention, which shows a schematic view of the driving mechanism, respectively showing the maximum distance that it can be raised and lowered.
Reference numbers in the figures: 1 is a cylindrical container; 2 is a square base; 3 is a rectangular supporting plate vertical to the base; 4 is a rectangular supporting plate parallel to the base and positioned at the diagonal line of the top; 5 is a circular flat plate; 6 is an electric mechanism; 7 is a computer automatic control system; 8 is a motor; 9 is a transmission mechanism; 10 is an external cylinder sleeve in the transmission mechanism; 11 is an internal cylindrical traction rod in the transmission mechanism; 12 is a plate for fixing the motor; 13 is a screw; 14 is an environment control connecting plate, 15 is an integrated control acquisition box, and 16 is a computer; a is the lowest position where the circular flat plate can descend; b is the highest position where the circular flat plate can rise.
Detailed Description
The invention is different from the existing experimental device, is a cylindrical container containing a lifting flat plate, can be used for carrying out non-evasive, discontinuous and repeated swimming experience experiments on experimental animals, and has the structure shown in figures 1, 2 and 4. The method comprises the following steps: the device comprises a cylindrical container 1, a basic support, a circular flat plate 5 and an electric mechanism 6, wherein the basic support consists of a square base 2, two vertical rectangular supporting plates 3 and rectangular supporting plates 4 fixed at the top ends of the two vertical rectangular supporting plates 3; the side length of the square base 2 is 30 cm, and the height of the two vertical rectangular support plates 3 is 52 cm; the cylindrical container is positioned at the center of the square base, the diameter of the cylindrical container 1 is 18 cm, and the height of the cylindrical container is 39 cm; the circular plate 5 has a diameter of 16 cm and is located inside the cylindrical container 1 with a 1 cm gap from its inner wall.
The electric mechanism comprises a motor 8 and a transmission mechanism 9 driven by the motor, and the motor pulls the circular flat plate to lift; the motor is fixed at one end of the rectangular supporting plate 4. The specific parameters of the motor are as follows: operating voltage 24 volts, power 72 watts, lifting/lowering speed 12 mm/s, thrust 100 kg, maximum stroke 300 mm.
The transmission mechanism comprises a cylinder sleeve 10 and a cylinder traction rod 11 arranged in the cylinder sleeve; the lower end of the cylindrical traction rod 11 is connected with the circular flat plate; the transmission mechanism is parallel to the peripheral edge of the cylindrical container, the length of the transmission mechanism is 38 cm, the length of the cylindrical sleeve structure is 20 cm, and the maximum length of the inner cylindrical traction rod is 18 cm.
The computer automation control system comprises an environment control connection board 14, an integrated control collection box 15 and a computer 16. The computer 16 transmits the control signal to the integrated control acquisition box 14 and the environment control connecting plate 15 in turn, and then the circular flat plate is automatically controlled to ascend or descend through an electric mechanism.
When the test container is used as a cylindrical test container, the circular flat plate 5 is positioned at the center of the interior of the cylindrical container, and the circular flat plate is lifted and lowered in the interior of the cylindrical container through the traction action of the electric mechanism, wherein the maximum distance for lifting and lowering is 15 centimeters, and the reference figure 5 shows that the circular flat plate is arranged in the center of the interior of the cylindrical container.
The round flat plate 5 is fixed at the lower end of the inner cylindrical traction rod 11 of the transmission mechanism through the screw 13, and the screw is semi-fixed, so that the round flat plate can not cause large splash when ascending or descending in water, the water surface is relatively calm, and the influence on the behavior of experimental animals due to water surface fluctuation can not be generated.
Claims (1)
1. A cylinder device of an automatic controllable lifting platform for behavioral experiments aims to enable an experimental animal to complete a non-evasive, discontinuous and repeated swimming experience for many times, the experience embodies a unique and brand-new experimental animal behavioral method, and a neurobiological mechanism of animal behavior abandoning is explored according to the experience; the device is characterized by comprising a basic bracket, a cylindrical container, a circular flat plate, an electric mechanism and a computer automatic control system; wherein:
the primary support, comprising: the square base is provided with two vertical rectangular supporting plates at diagonal positions of the square base, and the rectangular supporting plates are fixedly connected with the tops of the two vertical rectangular supporting plates and are parallel to the base;
the cylindrical container is used for containing experimental water; the square base is placed at the center of the square base;
the circular flat plate is positioned in the cylindrical container, and a gap is formed between the circular flat plate and the inner wall of the cylindrical container; the round flat plate is used for placing experimental animals;
the center of the square base, the center of the cylindrical container and the center of the circular flat plate are positioned on a straight line vertical to the base;
the electric mechanism comprises a motor and a transmission mechanism driven by the motor; the transmission mechanism is used for driving the circular flat plate in the cylindrical container to lift up and down; specifically, the motor is arranged on a rectangular support plate parallel to the base; the transmission mechanism comprises a cylindrical sleeve and a cylindrical traction rod arranged in the cylindrical sleeve; the lower end of the cylindrical traction rod is connected with the circular flat plate;
the computer automatic control system comprises an environment control connecting plate, an integrated control acquisition box and a computer; the computer transmits control signals to the integrated control acquisition box and the environment control connecting plate in sequence and controls electric work, so that the transmission mechanism is driven, and the circular flat plate in the cylindrical container rises and falls;
the specific operation flow of the device is as follows: firstly, a circular flat plate is arranged at the higher position of a cylindrical container, a proper amount of water is injected into the cylindrical container, and then the experimental animal is placed on the circular flat plate; the motor mechanism is controlled by the automatic computer control system to pull the circular flat plate to gradually descend until the experimental animal falls into the water and stays in the water for 15 seconds, and then the automatic computer control system controls the motor mechanism to pull the circular flat plate to gradually ascend so that the experimental animal leaves the water body;
the above operation process is repeated according to the design requirement.
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| CN202110385788.2A CN113243312B (en) | 2021-04-11 | 2021-04-11 | A cylinder device that is used for automatic controllable lift platform of behavioural experiment |
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| CN202110385788.2A CN113243312B (en) | 2021-04-11 | 2021-04-11 | A cylinder device that is used for automatic controllable lift platform of behavioural experiment |
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| CN113243312A CN113243312A (en) | 2021-08-13 |
| CN113243312B true CN113243312B (en) | 2022-09-16 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101811649B (en) * | 2009-12-01 | 2012-06-20 | 东莞宏威数码机械有限公司 | Automatic reciprocating type lifting gear |
| US20120079993A1 (en) * | 2010-09-30 | 2012-04-05 | University Of Durham | Behavioural apparatus |
| CN103749331B (en) * | 2013-12-26 | 2016-01-06 | 中国人民解放军成都军区总医院 | Animal imitating power exhausts swimming experiment device |
| CN103735319B (en) * | 2014-01-17 | 2015-11-25 | 中国人民解放军海军医学研究所 | Be applicable to the animal muscle power limit tolerance test device under environment under high pressure |
| CN103735332B (en) * | 2014-01-17 | 2015-11-25 | 中国人民解放军海军医学研究所 | Animal muscle power limit tolerance test method and device |
| CN108005452B (en) * | 2017-12-21 | 2019-11-08 | 镇江倍斯特曼新材料研究有限公司 | It is a kind of can automatic charging automatic garage |
| CN211470653U (en) * | 2019-12-20 | 2020-09-11 | 郑州百斯特机械制造有限公司 | Platform self-leveling control system |
| CN111358277A (en) * | 2020-04-03 | 2020-07-03 | 眉山华辰科技有限公司 | Single-motor double-shaft driving mechanism, feeding shovel stir-frying device and automatic cooker thereof |
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