CN113144284B - Zinc-titanium composite surface bone implant and preparation method thereof - Google Patents
Zinc-titanium composite surface bone implant and preparation method thereof Download PDFInfo
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- 239000007943 implant Substances 0.000 title claims abstract description 60
- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 57
- YJVLWFXZVBOFRZ-UHFFFAOYSA-N titanium zinc Chemical compound [Ti].[Zn] YJVLWFXZVBOFRZ-UHFFFAOYSA-N 0.000 title claims abstract description 50
- 239000002131 composite material Substances 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 238000002513 implantation Methods 0.000 title description 3
- 229910001297 Zn alloy Inorganic materials 0.000 claims abstract description 70
- 229910001069 Ti alloy Inorganic materials 0.000 claims abstract description 48
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims abstract description 46
- 229910052719 titanium Inorganic materials 0.000 claims abstract description 46
- 239000010936 titanium Substances 0.000 claims abstract description 46
- 238000005498 polishing Methods 0.000 claims abstract description 15
- 238000005242 forging Methods 0.000 claims abstract description 11
- 238000005488 sandblasting Methods 0.000 claims abstract description 10
- 239000002253 acid Substances 0.000 claims abstract description 9
- 230000007797 corrosion Effects 0.000 claims abstract description 4
- 238000005260 corrosion Methods 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 claims description 17
- 239000000463 material Substances 0.000 abstract description 9
- 230000000399 orthopedic effect Effects 0.000 abstract description 3
- 230000035807 sensation Effects 0.000 abstract description 2
- 239000010410 layer Substances 0.000 description 15
- 208000001132 Osteoporosis Diseases 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 238000005530 etching Methods 0.000 description 5
- 238000010883 osseointegration Methods 0.000 description 4
- 210000000963 osteoblast Anatomy 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 3
- 238000000227 grinding Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000003746 surface roughness Effects 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 238000002306 biochemical method Methods 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000004069 differentiation Effects 0.000 description 2
- 210000002997 osteoclast Anatomy 0.000 description 2
- 238000000053 physical method Methods 0.000 description 2
- 230000035755 proliferation Effects 0.000 description 2
- 229910000838 Al alloy Inorganic materials 0.000 description 1
- 208000010392 Bone Fractures Diseases 0.000 description 1
- 208000037408 Device failure Diseases 0.000 description 1
- 206010017076 Fracture Diseases 0.000 description 1
- 241000282414 Homo sapiens Species 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000037182 bone density Effects 0.000 description 1
- 230000008468 bone growth Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000011229 interlayer Substances 0.000 description 1
- 238000005468 ion implantation Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000011164 ossification Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 238000007745 plasma electrolytic oxidation reaction Methods 0.000 description 1
- 238000007750 plasma spraying Methods 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000007425 progressive decline Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/06—Titanium or titanium alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22F—CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS
- C22F1/00—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
- C22F1/16—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of other metals or alloys based thereon
- C22F1/165—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of other metals or alloys based thereon of zinc or cadmium or alloys based thereon
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22F—CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS
- C22F1/00—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
- C22F1/16—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of other metals or alloys based thereon
- C22F1/18—High-melting or refractory metals or alloys based thereon
- C22F1/183—High-melting or refractory metals or alloys based thereon of titanium or alloys based thereon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Thermal Sciences (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Mechanical Engineering (AREA)
- Metallurgy (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention relates to the technical field of orthopedic implant materials, and particularly provides a zinc-titanium composite surface-promoting bone implant and a preparation method thereof. The preparation method comprises the following steps: polishing, sand blasting and acid corrosion treatment are carried out on the pure titanium or titanium alloy bar to obtain a pretreated pure titanium or titanium alloy bar; polishing the inner wall of the zinc alloy bar after perforation treatment to obtain a zinc alloy pipe; preheating the zinc alloy pipe, and sleeving the pure titanium or titanium alloy bar into the preheated zinc alloy pipe to obtain a zinc-titanium bar; and performing multiple-pass rotary forging treatment on the zinc-titanium bar to obtain a zinc-titanium composite bar, and turning the zinc-titanium composite bar to obtain the zinc-titanium composite surface-driven bone implant with embedded threads and fixing holes. The bone implant provided by the invention has high overall structural stability and small exposed foreign body sensation, and can be widely applied to orthopedic implant materials.
Description
Technical Field
The invention relates to the technical field of orthopedic implant materials, and particularly provides a zinc-titanium composite surface-promoting bone implant and a preparation method thereof.
Background
Osteoporosis is a systemic disease that results in progressive decrease in overall bone mass, reduced bone density and destruction of bone microstructure, thereby causing increased bone fragility and susceptibility to fracture in patients. The pathological factors that lead to osteoporosis can be summarized as the destruction of the bone balance established by osteoclasts and osteoblasts, and the bone pits formed by the absorption of osteoclasts cannot be filled with new bone formed by osteoblasts, i.e. the reduction of the total bone mass occurs with a smaller amount of new bone mass than that absorbed. Aiming at osteoporosis of bone tissues around teeth, the tooth fixing force can be reduced, early falling is easy, and the life quality of a patient is seriously influenced.
The implant is considered as the third tooth of human beings, and after the implant denture is repaired, the chewing efficiency of the patient suffering from the deficiency of teeth can be improved to the greatest extent, and the alveolar bone absorption is delayed. However, osteoporosis can affect the process of implant osseointegration, resulting in prolonged healing time of the implant and even failure of implant integration. In order to promote implant osseointegration, reduce the influence of osteoporosis on implant osseointegration, improve the implant success rate of patients, a novel implant surface is generally constructed to promote implant osseointegration. At present, three main methods for promoting bone formation on the surface of an implant are as follows: (1) physical method: sand blasting, laser microetching, plasma spraying, ion implantation, physical gas phase hot working, ceramic treatment and the like; (2) chemical method: anodic oxidation, micro-arc oxidation, sol-gel technology, acid-base treatment, etc.: (3) biochemical method: the surface adsorbs biomolecules, chemical bond grafted proteins or polypeptides, etc. However, the physical method or the chemical method only increases the surface roughness or the bone compatibility of the implant, and the problem of the bone mass loss of the osteoporosis is not improved. While biochemical methods have certain bone effect, processes such as loading grafting of biomacromolecules are not easy to industrialize, and the quality guarantee period of products is short.
Disclosure of Invention
Aiming at the problems existing in the prior art, the invention forms the zinc alloy-pure titanium or titanium alloy composite implant by compounding a layer of zinc alloy coat on the surface of the pure titanium or titanium alloy implant; the pure titanium or titanium alloy bar is pretreated to obtain the composite bar which has large surface area and is beneficial to bone growth, the bar is sleeved into the aluminum alloy pipe and is subjected to rotary forging to obtain the composite bar which is inlaid stably and can bear turning, and the bone implant with embedded threads and fixing holes is obtained after turning, so that the bone implant has high stability and small exposed foreign body sensation.
In order to achieve the aim of the invention, the invention provides a preparation method of a zinc-titanium composite surface-driven bone implant, which specifically comprises the following steps:
polishing, sand blasting and acid corrosion treatment are carried out on the pure titanium or titanium alloy bar to obtain a pretreated pure titanium or titanium alloy bar;
polishing the inner wall of the zinc alloy bar after perforation treatment to obtain a zinc alloy pipe;
preheating the zinc alloy pipe, and sleeving the pure titanium or titanium alloy bar into the preheated zinc alloy pipe to obtain a zinc-titanium bar;
and performing multiple-pass rotary forging treatment on the zinc-titanium bar to obtain a zinc-titanium composite bar, and turning the zinc-titanium composite bar to obtain the zinc-titanium composite surface-driven bone implant with embedded threads and fixing holes.
Further, the diameter of the pure titanium or titanium alloy bar is 9-20mm, the outer diameter of the zinc alloy pipe is 11-40mm, and the wall thickness is 1-10mm.
Further, the diameter of the zinc-titanium composite bar is 4-10mm.
Further, the multi-pass rotary swaging treatment comprises at least two passes of hot rotary swaging and at least two passes of cold rotary swaging, and the temperature of the hot rotary swaging is 150-190 ℃.
Based on the same inventive concept, the invention also provides a zinc-titanium composite surface-promoting bone implant obtained by the preparation method, wherein the bone implant comprises a pure titanium or titanium alloy bar and a zinc alloy tube;
the surface of the zinc alloy pipe is provided with embedded threads; the part of the pure titanium or titanium alloy bar, which is higher than the zinc alloy tube, is a bone implant shoulder, and a fixing hole is arranged in the center of the bone implant shoulder; the lower end of the bone implant is turned into a cone.
Further, the fixing holes comprise round table holes, right polygonal row holes and threaded holes; the round table hole, the regular polygon hole and the threaded hole are concentrically arranged from top to bottom.
Further, the surface of the pure titanium or titanium alloy bar is provided with 10-50 mu m pit-shaped undulation.
Further, the embedded thread comprises a thread crest and a thread root, and the distance from the thread root to the pure titanium or titanium alloy bar is 0.1-0.4mm.
The beneficial effects are that:
(1) The implant embedded thread part is made of degradable zinc alloy material, and the degradable zinc alloy can promote differentiation and proliferation of osteoblasts and increase local tissue bone mass along with gradual degradation of the zinc alloy layer;
(2) The pure titanium or titanium alloy base layer is subjected to polishing, sand blasting and acid etching in advance, the surface roughness is large, and then when the pure titanium or titanium alloy base layer is assembled with the zinc alloy pipe through a rotary forging process, the zinc alloy pipe layer is fully meshed and inlaid with the pure titanium or titanium alloy bar material, so that the pure titanium or titanium alloy bar material is firmly combined, and after the zinc alloy is degraded, bone tissues are gradually stretched into the pure titanium or titanium alloy bar material rough layer, so that the new bone tissues fully wrap and fix the implant, and the implant stability is improved;
(3) The combination of the zinc alloy pipe and the pure titanium or titanium alloy bar is stable through a plurality of pass rotary forging processes, so that the two materials can bear mechanical turning and no interlayer stripping of the materials occurs;
(4) After the implant is subjected to turning, the root thread part is required to be a zinc alloy pipe layer, and the shoulder part is required to be a pure titanium or titanium alloy bar layer, so that the root of the whole structure is larger, the shoulder part is smaller, the stability of the implant is higher, and the exposed foreign body feeling is smaller.
Drawings
FIG. 1 is a schematic cross-sectional view of a zinc-titanium composite bar according to an embodiment of the present invention;
fig. 2 is a schematic cross-sectional view of a zinc-titanium composite surface-promoting bone implant according to an embodiment of the present invention.
[ reference numerals description ]
1. A zinc alloy tube layer; 2. pure titanium or titanium alloy bars; 3. round table holes; 4. a positive polygonal row of holes; 5. a threaded hole; 6. thread crests; 7. thread root.
Detailed Description
In order to make the technical problems, technical solutions and advantages to be solved by the present invention more apparent, the following detailed description will be provided with reference to specific embodiments, but the scope of the present invention is not limited to the following specific embodiments.
Unless defined otherwise, all technical and scientific terms used hereinafter have the same meaning as commonly understood by one of ordinary skill in the art. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the scope of the present invention.
Unless otherwise specifically indicated, the various raw materials, reagents, instruments, equipment and the like used in the present invention are commercially available or may be prepared by existing methods.
In the embodiment of the invention, the zinc-titanium composite surface-facilitated bone implant and the preparation method thereof comprise the following steps:
sequentially polishing, sand blasting and acid etching the surface of a pure titanium or titanium alloy bar with the diameter of 9-20mm to obtain a pretreated pure titanium or titanium alloy bar; the zinc alloy bar with the diameter of 11-40mm is perforated, and the inner wall after perforation is polished and ground to form a zinc alloy pipe with the outer diameter of 11-40mm and the wall thickness of 1-10 mm; preheating a zinc alloy pipe with the outer diameter of 11-40mm and the wall thickness of 1-10mm, sleeving the zinc alloy pipe into the pretreated pure titanium or titanium alloy bar after the diameter of the zinc alloy pipe is enlarged after the zinc alloy pipe is heated, and tightly fixing the zinc alloy pipe and the pure titanium or titanium alloy bar after the zinc alloy pipe is cooled to room temperature to form a zinc-titanium bar; the combined zinc-titanium bar is subjected to a plurality of passes of rotary forging processes to obtain a zinc-titanium composite bar with the diameter of 4-10mm, wherein the zinc-titanium composite bar is shown in a figure 1 and comprises a zinc alloy pipe layer 1 and a pure titanium or titanium alloy bar 2, and then the zinc-titanium composite bar is subjected to mechanical turning treatment to obtain a bone implant, as shown in a figure 2, the bone implant consists of the zinc alloy pipe layer 1 and the pure titanium or titanium alloy bar 2, the part, higher than the zinc alloy pipe layer 1, of the pure titanium or titanium alloy bar 2 at the upper end of the bone implant is provided with a bone implant shoulder, and the center of the bone implant shoulder is concentrically provided with a round table hole 3, a regular polygon hole 4 and a threaded hole 5 from top to bottom for fixedly connecting the bone implant with a base station; the surface of the pure titanium or titanium alloy bar 2 is subjected to polishing, sand blasting and acid corrosion treatment to obtain bullet pit-shaped fluctuation with the diameter of 10-50 mu m, so that the surface roughness is large, the pure titanium or titanium alloy bar can be meshed and inlaid with a zinc alloy pipe layer, is firmly combined, and is beneficial to bone ingrowth after the zinc alloy layer is degraded; the zinc alloy pipe layer 1 is provided with an embedded thread, the embedded thread comprises a thread crest 6 and a thread root 7, the distance from the thread root 7 to the pure titanium or titanium alloy bar 2 is 0.1-0.4mm, the material of the embedded thread part of the bone implant is degradable zinc alloy, the embedded thread part can be gradually degraded after implantation, the differentiation and proliferation of osteoblasts are promoted, and the bone mass of local tissues is increased.
The following is further illustrated by specific examples.
Example 1
And (3) sequentially polishing, sand blasting and acid etching the surface of the pure titanium bar with the diameter of 9mm to obtain the pretreated pure titanium bar. And (3) perforating the zinc alloy bar with the diameter of 11mm, polishing and grinding the inner wall after perforation to form the zinc alloy pipe with the outer diameter of 11mm and the wall thickness of 1 mm. After the zinc alloy pipe with the outer diameter of 11mm and the wall thickness of 1mm is preheated, the diameter of the zinc alloy pipe is enlarged when the zinc alloy pipe is heated, the zinc alloy pipe is sleeved into the pretreated pure titanium bar, and after the temperature is reduced to the room temperature, the zinc alloy pipe contracts when the zinc alloy pipe is cooled, and the zinc alloy pipe and the pure titanium bar are tightly fixed to form the zinc-titanium bar. And the combined zinc-titanium bar is subjected to 2-pass hot rotary forging and 2-pass cold rotary forging processes to obtain the composite zinc-titanium bar with the diameter of 4mm. The composite zinc-titanium bar is mechanically turned into a bone implant with embedded threads and fixing holes as shown in the structure of figure 2.
Example 2
And (3) sequentially polishing, sand blasting and acid etching the surface of the titanium alloy bar with the diameter of 20mm to obtain the pretreated titanium alloy bar. And (3) perforating the zinc alloy bar with the diameter of 40mm, polishing and grinding the inner wall after perforation to form the zinc alloy pipe with the outer diameter of 40mm and the wall thickness of 10mm. After the zinc alloy pipe with the outer diameter of 40mm and the wall thickness of 10mm is preheated, the diameter of the zinc alloy pipe is enlarged when the zinc alloy pipe is heated, the zinc alloy pipe is sleeved into the pretreated titanium alloy bar, and after the temperature is reduced to the room temperature, the zinc alloy pipe contracts when the zinc alloy pipe is cooled, and the zinc alloy pipe and the titanium alloy bar are tightly fixed to form the zinc-titanium bar. The combined zinc-titanium bar is subjected to 4-pass hot rotary forging and 8-pass cold rotary forging to obtain the composite zinc-titanium bar with the diameter of 10mm. The composite zinc-titanium bar is mechanically turned into a bone implant with embedded threads and fixing holes as shown in the structure of figure 2.
Example 3
And (3) sequentially polishing, sand blasting and acid etching the surface of the titanium alloy bar with the diameter of 15mm to obtain the pretreated pure titanium or titanium alloy bar. And (3) perforating the zinc alloy bar with the diameter of 25mm, polishing and grinding the inner wall after perforation to form the zinc alloy pipe with the outer diameter of 25mm and the wall thickness of 5 mm. After the zinc alloy pipe with the outer diameter of 25mm and the wall thickness of 5mm is preheated, the diameter of the zinc alloy pipe is enlarged when the zinc alloy pipe is heated, the zinc alloy pipe is sleeved into the pretreated pure titanium or titanium alloy bar, and after the temperature is reduced to the room temperature, the zinc alloy pipe contracts when encountering cold, and is tightly fixed with the titanium alloy bar to form the zinc-titanium bar. And (3) carrying out 3-pass hot rotary swaging and 5-pass cold rotary swaging on the assembled zinc-titanium bar to obtain the composite zinc-titanium bar with the diameter of 7 mm. The composite zinc-titanium bar is mechanically turned into a bone implant with embedded threads and fixing holes as shown in the structure of figure 2.
The above embodiments are only preferred embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be able to apply equivalents and modifications according to the technical solution and the concept of the present invention within the scope of the present invention.
Claims (8)
1. The preparation method of the zinc-titanium composite surface-facilitated bone implant is characterized by comprising the following steps of:
polishing, sand blasting and acid corrosion treatment are carried out on the pure titanium or titanium alloy bar to obtain a pretreated pure titanium or titanium alloy bar;
polishing the inner wall of the zinc alloy bar after perforation treatment to obtain a zinc alloy pipe;
preheating the zinc alloy pipe, and sleeving the pure titanium or titanium alloy bar into the preheated zinc alloy pipe to obtain a zinc-titanium bar;
and performing multiple-pass rotary forging treatment on the zinc-titanium bar to obtain a zinc-titanium composite bar, and turning the zinc-titanium composite bar to obtain the zinc-titanium composite surface-driven bone implant with embedded threads and fixing holes.
2. The method for preparing a zinc-titanium composite surface-promoting bone implant according to claim 1, wherein the diameter of the pure titanium or titanium alloy bar is 9-20mm, the outer diameter of the zinc alloy tube is 11-40mm, and the wall thickness is 1-10mm.
3. The method for preparing a zinc-titanium composite surface-promoting bone implant according to claim 1, wherein the diameter of the zinc-titanium composite rod is 4-10mm.
4. The method for preparing a zinc-titanium composite surface-promoting bone implant according to claim 1, wherein the multi-pass swaging treatment comprises at least two-pass hot swaging and at least two-pass cold swaging, and the temperature of the hot swaging is 150-190 ℃.
5. The method for preparing a zinc-titanium composite surface-promoting bone implant according to claim 1, wherein the bone implant comprises pure titanium or titanium alloy bars and zinc alloy tubes;
the surface of the zinc alloy pipe is provided with embedded threads; the part of the pure titanium or titanium alloy bar, which is higher than the zinc alloy tube, is a bone implant shoulder, and a fixing hole is arranged in the center of the bone implant shoulder; the lower end of the bone implant is turned into a cone.
6. The method for preparing a zinc-titanium composite surface-promoting bone implant according to claim 5, wherein the fixing holes comprise round table holes, right polygonal row holes and threaded holes; the round table hole, the regular polygon hole and the threaded hole are concentrically arranged from top to bottom.
7. The method for preparing a zinc-titanium composite surface-promoting bone implant according to claim 5, wherein the surface of the pure titanium or titanium alloy bar is provided with 10-50 μm pit-like undulations.
8. The method of claim 5, wherein the embedded thread comprises a thread crest and a thread root, and the distance from the thread root to the pure titanium or titanium alloy bar is 0.1-0.4mm.
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