CN113143290A - Data synchronization method of electroencephalogram device and electroencephalogram device - Google Patents

Data synchronization method of electroencephalogram device and electroencephalogram device Download PDF

Info

Publication number
CN113143290A
CN113143290A CN202110482597.8A CN202110482597A CN113143290A CN 113143290 A CN113143290 A CN 113143290A CN 202110482597 A CN202110482597 A CN 202110482597A CN 113143290 A CN113143290 A CN 113143290A
Authority
CN
China
Prior art keywords
subsystem
data
communication protocol
wireless communication
processing system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202110482597.8A
Other languages
Chinese (zh)
Other versions
CN113143290B (en
Inventor
王浩冲
史改革
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xi'an Zhentai Intelligent Technology Co ltd
Original Assignee
Xi'an Zhentai Intelligent Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xi'an Zhentai Intelligent Technology Co ltd filed Critical Xi'an Zhentai Intelligent Technology Co ltd
Priority to CN202110482597.8A priority Critical patent/CN113143290B/en
Publication of CN113143290A publication Critical patent/CN113143290A/en
Application granted granted Critical
Publication of CN113143290B publication Critical patent/CN113143290B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0022Monitoring a patient using a global network, e.g. telephone networks, internet

Abstract

The invention discloses a data synchronization method of an electroencephalogram device and the electroencephalogram device, comprising the following steps: the central processing system sends an instruction to each subsystem through a first wireless communication protocol so as to complete the synchronization of each subsystem; the system comprises an acquisition subsystem, a marking subsystem and a central processing system, wherein the acquisition subsystem acquires data information and transmits the data information at a preset frequency, adds a first time stamp corresponding to the data information into a data packet, and transmits the data information to the central processing system; the central processing system receives the data packet sent by the acquisition subsystem through a second wireless communication protocol, acquires a current second timestamp from the marking subsystem through a wired communication protocol, a first wireless communication protocol or a second wireless communication protocol, and aligns a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem.

Description

Data synchronization method of electroencephalogram device and electroencephalogram device
Technical Field
The embodiment of the invention relates to the technical field of biological information, in particular to a data synchronization method of an electroencephalogram device and the electroencephalogram device.
Background
Event-related evoked potentials (ERP) are the brain electrical signals (EEG) caused by specific stimuli that reflect neuroelectrophysiological changes in the cognitive processes of the brain under stimulation. In the electroencephalogram signal acquisition process, events and data often have a strict time-locking relationship, such as event-related evoked potentials (ERP) and phase-related steady-state visual evoked potentials. Therefore, when electroencephalogram data are recorded, the time when an event occurs needs to be accurately recorded, and the time error of the event and the data is required to be +/-1 ms.
The existing synchronization methods mainly include two types: one is digital wired synchronization, and specifically comprises: the event generator can generate Transistor-Transistor Logic (TTL) level signals while generating events, and the TTL level signals are transmitted to the electroencephalogram acquisition device in a wired mode. And after the electroencephalogram acquisition device detects the TTL level, a synchronous label is added to the data to mark the occurrence time of the event. The other one is analog wired synchronization, which specifically comprises the following steps: the synchronous trigger signal generated by the event generator is directly connected to 1 lead of the multi-lead electroencephalogram acquisition device, and the trigger signal and the electroencephalogram signal are acquired simultaneously. And the synchronization of events and data can be realized by analyzing the collected data of the triggering signal leads and the EEG signal leads.
However, most of the existing high-precision data transmission methods are wired transmission, and the event generator and the electroencephalogram acquisition system are required to be connected in a wired mode, so that great inconvenience is brought to relevant experiments and researches. The existing wireless data synchronization technology has the disadvantages of low transmission speed, low transmission efficiency and complex transmission process, and is difficult to realize the synchronous acquisition of various stimulation systems.
Disclosure of Invention
The embodiment of the invention provides a data synchronization method of an electroencephalogram device and the electroencephalogram device, which are used for realizing wireless data synchronization of a general computer and wireless electroencephalogram equipment, aligning events in the computer with electroencephalogram acquisition data, ensuring that the synchronization precision is within 1ms, being applicable to various stimulation events and realizing data synchronization of a plurality of electroencephalogram acquisition devices.
In a first aspect, an embodiment of the present invention provides a data synchronization method for an electroencephalogram device, where the electroencephalogram device includes a central processing system, a labeling subsystem, and at least one acquisition subsystem;
the data synchronization method of the electroencephalogram device comprises the following steps:
the central processing system sends an instruction to the marking subsystem and the acquisition subsystem through a first wireless communication protocol so as to complete the synchronization of the marking subsystem and the acquisition subsystem;
the acquisition subsystem acquires data information and transmission data information at a preset frequency, adds a first time stamp corresponding to the data information into a data packet, and sends the data packet and the data information to the central processing system, and meanwhile, the marking subsystem sends a second time stamp at a corresponding moment of an event occurrence signal according to the event occurrence signal transmitted by the central processing system through a wired communication protocol; wherein the data information in the data packet comprises consecutive 1 st signal data point, …, i-1 st signal data point and i signal data point, i is a positive integer;
and the central processing system receives the data packet sent by the acquisition subsystem through a second wireless communication protocol, acquires a current second timestamp from the marking subsystem through the wired communication protocol, the first wireless communication protocol or the second wireless communication protocol, and aligns a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem.
Optionally, the first timestamp includes:
…, a 1 st sampling time point corresponding to the 1 st signal data point, an i-1 st sampling time point corresponding to the i-1 st signal data point, and an i-th sampling time point corresponding to the i-th signal data point; alternatively, the first and second electrodes may be,
sequence numbers 1 and … corresponding to the 1 st signal data point, sequence number 2 corresponding to the i-1 st signal data point, and sequence number i corresponding to the i-th signal data point.
Optionally, the sending, by the central processing system, an instruction to the tagging subsystem and the collecting subsystem through a first wireless communication protocol includes:
step 111, the central processing system sends a preparation start synchronization instruction to the marking subsystem and the acquisition subsystem through a first wireless communication protocol;
step 112, the marking subsystem and the collecting subsystem respond to the central processing system according to the preparation starting synchronous instruction to prepare a finishing instruction;
and step 113, the central processing system determines the marking subsystem and the acquisition subsystem to complete preparation and start synchronization according to the preparation completion instruction, and sends a synchronization instruction to the marking subsystem and the acquisition subsystem through the first wireless communication protocol, so that the marking subsystem resets the time stamp according to the synchronization instruction and the acquisition subsystem resets the time stamp according to the synchronization instruction.
Optionally, after step 113, the method further includes:
the central processing system sends a synchronous query instruction to the at least one acquisition subsystem and the marking subsystem simultaneously through a first wireless communication protocol;
the acquisition subsystem responds a first initial timestamp to the central processing system at the moment according to the synchronous query instruction, and the marking subsystem responds a second initial timestamp to the central processing system at the moment according to the synchronous query instruction;
the central processing system judges whether the difference value of the first initial timestamp and the second initial timestamp is within a first preset range;
and if the difference value of the first initial timestamp and the second initial timestamp is within a first preset range, completing the synchronization of the marking subsystem and the acquisition subsystem.
Optionally, if the difference between the first initial timestamp and the second initial timestamp is not within the first preset range, the step 113 is returned to until the difference between the first initial timestamp and the second initial timestamp is within the first preset range.
Optionally, the marking subsystem includes a first chip, and the collecting subsystem includes a second chip;
the first chip and the second chip are of the same chip type.
Optionally, the acquisition subsystem includes at least one of an electroencephalogram acquisition device, a myoelectricity acquisition device and an electrocardiograph acquisition device;
the data information comprises an electroencephalogram signal, an electromyogram signal or an electrocardiosignal.
Optionally, the wired communication protocol includes one of TTL, SDIO protocol, parallel port communication, serial port communication, USB protocol, and HMDI protocol;
the first wireless communication protocol includes: UDP protocol or ICMP protocol;
the second wireless communication protocol includes: TCP/IP protocol.
In a second aspect, an embodiment of the present invention further provides an electroencephalogram device, configured to implement the data synchronization method of the electroencephalogram device according to the first aspect, where the electroencephalogram device includes: the system comprises a central processing system, a marking subsystem and at least one acquisition subsystem;
the central processing system is used for sending instructions to the marking subsystem and the acquisition subsystem through a first wireless communication protocol so as to complete the synchronization of the marking subsystem and the acquisition subsystem;
the acquisition subsystem is used for acquiring data information and transmitting the data information at a preset frequency, adding a first time stamp corresponding to the data information into a data packet, and sending the data packet and the data information to the central processing system; wherein the data information in the data packet comprises consecutive 1 st signal data point, …, i-1 st signal data point and i signal data point, i is a positive integer;
the marking subsystem is used for sending a second timestamp of a corresponding moment of an event occurrence signal according to the event occurrence signal transmitted by the central processing system through a wired communication protocol;
the central processing system is further configured to receive a data packet sent by the acquisition subsystem through a second wireless communication protocol, acquire a current second timestamp from the marking subsystem through the wired communication protocol, the first wireless communication protocol, or the second wireless communication protocol, and align a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem.
Optionally, the central processing system includes a data processing module, a first wired communication module and a first wireless communication module;
the marking subsystem comprises a second wired communication module and a second wireless communication module;
the acquisition subsystem comprises a data acquisition processing module and a network communication module;
the first wired communication module is used for establishing wired connection with the second wired communication module through a wired communication protocol;
the first wireless communication module is used for establishing wireless network connection with the second wireless communication module through a first wireless communication protocol; the wireless network communication module is also used for establishing wireless network connection with the network communication module through a first wireless communication protocol and a second wireless communication protocol;
the data processing module is used for sending instructions to the marking subsystem and the acquisition subsystem through the first wireless communication module in the central processing system in the first wireless communication protocol so as to complete the synchronization of the marking subsystem and the acquisition subsystem;
the data acquisition processing module is used for acquiring data information and transmitting the data information at a preset frequency, adding a first time stamp corresponding to the data information into a data packet, transmitting the data packet and the data information to the data processing module, and meanwhile, the marking subsystem transmits a second time stamp at a corresponding moment of an event occurrence signal according to the event occurrence signal transmitted by the data processing module through the wired communication protocol;
the data processing module is further configured to receive a data packet sent by the acquisition subsystem through the second wireless communication protocol, acquire a current second timestamp from the marking subsystem through the wired communication protocol, the first wireless communication protocol, or the second wireless communication protocol, and align a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem.
The electroencephalogram device provided by the embodiment of the invention is provided with the marking subsystem, the central processing system controls the occurrence of the event, when the event occurs, the central processing system transmits an event occurrence signal to the marking subsystem through the low-delay wired transmission protocol, and when the marking subsystem receives the event occurrence signal, the marking subsystem immediately sends the timestamp of the current moment to the central processing system through the low-delay wired transmission protocol or the wireless communication protocol, so that the central processing system determines the data corresponding to the timestamp when the event occurs according to the timestamp, the delay problem is avoided, and the time position of the event is accurately aligned with the data position of the electroencephalogram and the like. In addition, when the electroencephalogram device comprises a plurality of acquisition subsystems, data information of the acquisition subsystems can be aligned with each other, and high-precision synchronization of the acquired data is guaranteed; the data synchronization method and the electroencephalogram device provided by the embodiment of the invention can be applied to various stimulation events.
Drawings
FIG. 1 is a schematic structural diagram of an electroencephalogram device provided by an embodiment of the present invention;
FIG. 2 is a flowchart of a data synchronization method of an electroencephalogram device according to an embodiment of the present invention;
FIG. 3 is a flowchart of a data synchronization method for an electroencephalogram device according to an embodiment of the present invention;
FIG. 4 is a flowchart of a data synchronization method for an electroencephalogram device according to an embodiment of the present invention;
fig. 5 is a schematic structural diagram of another electroencephalogram device provided by an embodiment of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be further noted that, for the convenience of description, only some of the structures related to the present invention are shown in the drawings, not all of the structures.
Fig. 1 is a schematic structural diagram of an electroencephalogram device provided by an embodiment of the present invention, and as shown in fig. 1, the electroencephalogram device 100 provided by the embodiment of the present invention includes a central processing system 10, a marking subsystem 20, and at least one acquisition subsystem 30, where fig. 1 illustrates that the electroencephalogram device 100 includes two acquisition subsystems 30. A central processing system 10 for sending instructions to the marking subsystem 20 and the acquisition subsystem 30 via a first wireless communication protocol to complete synchronization of the marking subsystem 20 and the acquisition subsystem 30. The acquisition subsystem 30 is used for acquiring data information and transmitting the data information at a preset frequency, adding a first time stamp corresponding to the data information into a data packet, and sending the data packet and the data information to the central processing system 10; the data information in the data packet comprises continuous 1 st signal data point, …, i-1 st signal data point and ith signal data point, wherein i is a positive integer; and a marking subsystem 20 for sending a second time stamp of the corresponding time of the event occurrence signal according to the event occurrence signal transmitted by the central processing system 10 through the wired communication protocol. The central processing system 10 is further configured to receive the data packet sent by the acquisition subsystem 30 through the second wireless communication protocol, acquire a current second timestamp from the marking subsystem 20 through the wired communication protocol, the first wireless communication protocol, or the second wireless communication protocol, and align a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem 20.
Fig. 2 is a flowchart of a data synchronization method of an electroencephalogram device according to an embodiment of the present invention, and as shown in fig. 2, the data synchronization method of the electroencephalogram device according to the embodiment of the present invention includes:
and step 110, the central processing system sends an instruction to the marking subsystem and the acquisition subsystem through a first wireless communication protocol so as to complete the synchronization of the marking subsystem and the acquisition subsystem.
Wherein the first wireless communication protocol comprises: UDP protocol or ICMP protocol, etc. The marking subsystem 20 and the collecting subsystem 30 are two independent systems respectively, the marking subsystem 20 is used for transmitting the time stamp, and the collecting subsystem 30 is used for transmitting the collected data information; alternatively, both data information and time stamps are transmitted. The acquisition subsystem 30 includes at least one of an electroencephalogram acquisition device, an electromyogram acquisition device and an electrocardiograph acquisition device, and correspondingly, the data information includes an electroencephalogram signal, an electromyogram signal or an electrocardiograph signal. The tagging subsystem 20 may be plugged into the central processing system 10 via USB, for example.
Illustratively, before the acquisition subsystem 30 transmits the data information, the central processing system 10 sends commands to the acquisition subsystem 30 (e.g., an electroencephalogram acquisition device) and the marking subsystem 20 simultaneously via a wireless broadcast protocol (e.g., UDP protocol) to complete the synchronization of the marking subsystem 20 and the acquisition subsystem 30. If there are multiple acquisition subsystems 30, the timestamps of all the acquisition subsystems 30 are also aligned due to the UDP broadcast method.
Optionally, the marking subsystem 20 includes a first chip, and the collecting subsystem 30 includes a second chip; the first chip and the second chip are of the same chip type. That is, the acquisition subsystem 30 and the marking subsystem 20 use embedded hardware, so that high-precision synchronization can be completed when the marking subsystem 20 and the acquisition subsystem 30 receive instructions simultaneously, and error accumulation is slow in subsequent acquisition.
And step 120, the acquisition subsystem acquires data information and transmits the data information at a preset frequency, adds a first time stamp corresponding to the data information into a data packet, transmits the data packet and the data information to the central processing system, and simultaneously transmits a second time stamp at a time corresponding to an event occurrence signal according to the event occurrence signal transmitted by the central processing system through a wired communication protocol.
The wired communication protocol comprises one of TTL, SDIO protocol, parallel port communication, serial port communication, USB protocol and HMDI protocol.
The data packet includes both consecutive signal data points, including signal data point 1, signal data point …, signal data point i-1, and signal data point i, and a first time stamp; the first timestamp comprises a point count form or a time form; the time form is for example: …, a 1 st sampling time point corresponding to the 1 st signal data point, an i-1 st sampling time point corresponding to the i-1 st signal data point, and an i-th sampling time point corresponding to the i-th signal data point; the sampling time point may be a specific time, for example, the 1 st sampling time point corresponding to the 1 st signal data point is 0.01s, and the 2 nd sampling time point corresponding to the 2 nd signal data point is 0.02s, …. The dot count form is, for example: for example, the sequence number corresponding to the signal data point is 1, the time stamp corresponding to the 1 st signal data point is 2, …, and the time stamp corresponding to the i-th signal data point is i.
Illustratively, when the first time stamp is in the form of time, after the marking subsystem 20 and the acquisition subsystem 30 are synchronized, the time stamps of all the acquisition subsystems 30 and the time stamps of the marking subsystem 20 are accumulated at the same time interval, and all the acquisition subsystems 30 acquire and transmit data at the same frequency. When an event occurs, transmitting an event occurrence signal to the marking subsystem 20 through a low-latency wired transmission protocol, and the marking subsystem 20 transmitting a timestamp at this time, i.e., a second timestamp, to the central processing system 10 through a wired communication protocol; wherein the second timestamp is also typically single independent, since the event occurrences are separate (e.g., flashing visual stimulus occurring at a certain time). The acquisition subsystem 30 transmits data including the successive sampling time points and all signal data points corresponding to the successive sampling time points to the central processing system 10.
It should be noted that although there is still a delay of millisecond in the signal transmission process, this delay is a fixed system error and can be eliminated by data processing.
Step 130, the central processing system receives the data packet sent by the acquisition subsystem through the second wireless communication protocol, acquires a current second timestamp from the marking subsystem through the wired communication protocol, the first wireless communication protocol or the second wireless communication protocol, and aligns a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem.
Wherein the second wireless communication protocol comprises: TCP/IP protocol, etc.
Illustratively, the first timestamp and the second timestamp, in this example in the form of a point count, such as 1, 2, 3, 4 … … N, where N is the total number of collected points. For example, the sampling rate of the system is 256Hz, the total number of sampling points at time t is t × 256, and if an event occurs at this time, the second timestamp returned by the tagging subsystem 20 is "t × 256", and it can be known by the central processing system 10 that the data at the time t × 256 sampling points in the data packet returned by the acquisition subsystem 30 is the data at the time when the event starts to occur. The data position of the event occurrence moment can be accurately determined.
Because the wireless brain electricity collection system and the general computer central processing system in the prior art carry out data transmission such as brain electricity, the wireless connection protocol adopts high-delay protocols such as TCP/IP, the transmission time is long, and the real-time performance is poor, so when the general computer central processing system generates an event, the timestamps in the collection system cannot be directly read for alignment. In the embodiment of the present invention, when the general-purpose computer central processing system generates an event, the event can be transmitted to the marking subsystem 20 through the wired connection, so that the marking subsystem 20 can timely stamp the time corresponding to the event, thereby avoiding the delay problem and accurately aligning the time position of the event to the data position of electroencephalogram and the like.
To sum up, in the technical solution provided in the embodiment of the present invention, a marking subsystem is arranged in the electroencephalogram device, the central processing system controls an event, when the event occurs, the marking subsystem transmits an event occurrence signal to the marking subsystem through a low-delay wired transmission protocol, and when the marking subsystem receives the event occurrence signal, the marking subsystem immediately transmits a timestamp of the current time to the central processing system through the low-delay wired transmission protocol or a wireless transmission protocol, so that the central processing system determines, according to the timestamp, data corresponding to the timestamp when the event occurs, thereby avoiding a delay problem, and enabling an event time position to be accurately aligned with an electroencephalogram data position. In addition, when the electroencephalogram device comprises a plurality of acquisition subsystems, data information of the acquisition subsystems can be aligned with each other, and high-precision synchronization of the acquired data is guaranteed; the data synchronization method and the electroencephalogram device provided by the embodiment of the invention can be applied to various stimulation events.
Optionally, fig. 3 is a flowchart of another data synchronization method for an electroencephalogram device according to an embodiment of the present invention, where the data synchronization method for the electroencephalogram device and the data synchronization method for the electroencephalogram device according to the above embodiments belong to the same inventive concept, and details that are not described in detail in this embodiment may refer to an embodiment of the data synchronization method for the electroencephalogram device. As shown in fig. 3, the data synchronization method for an electroencephalogram device according to an embodiment of the present invention includes:
and step 211, the central processing system sends a preparation start synchronization instruction to the marking subsystem and the acquisition subsystem through the first wireless communication protocol.
Wherein the central processing system 10 sends a ready to start synchronization instruction to the tagging subsystem 20 and the acquisition subsystem 30 via the first wireless communication protocol, i.e., the central processing system 10 determines whether the tagging subsystem 20 and the acquisition subsystem 30 can be synchronized at this time.
Step 212, the tagging subsystem and the acquisition subsystem respond to the central processing system with a ready to complete command based on the ready to start synchronization command.
Wherein the marking subsystem 20 and the acquisition subsystem 30 respond to the central processing system that synchronization is possible based on the prepare start synchronization command.
And step 213, the central processing system determines the marking subsystem and the acquisition subsystem according to the preparation completion instruction to complete preparation and start synchronization, and sends a synchronization instruction to the marking subsystem and the acquisition subsystem through the first wireless communication protocol, so that the marking subsystem resets the time stamp according to the synchronization instruction and the acquisition subsystem resets the time stamp according to the synchronization instruction.
When the central processing system 10 receives the message that the marking subsystem 20 and the collecting subsystem 30 can synchronize, the central processing system 10 sends a synchronization instruction to the marking subsystem 20 and the collecting subsystem 30 through the first wireless communication protocol, so that the marking subsystem 20 resets its timestamp according to the synchronization instruction and the collecting subsystem 30 resets its timestamp according to the synchronization instruction, so as to complete the synchronization of the marking subsystem 20 and the collecting subsystem 30.
Step 220, the acquisition subsystem acquires data information and transmits the data information at a preset frequency, adds a first time stamp corresponding to the data information into a data packet, transmits the data packet and the data information to the central processing system, and simultaneously, the marking subsystem transmits a second time stamp at a time corresponding to an event occurrence signal according to the event occurrence signal transmitted by the central processing system through a wired communication protocol; wherein the data information in the data packet includes consecutive 1 st signal data point, …, i-1 st signal data point and i signal data point, i being a positive integer.
Step 230, the central processing system receives the data packet sent by the acquisition subsystem through the second wireless communication protocol, and acquires a current second timestamp from the marking subsystem through the wired communication protocol, the first wireless communication protocol, or the second wireless communication protocol, and aligns a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem.
Optionally, fig. 4 is a flowchart of another data synchronization method for an electroencephalogram device according to an embodiment of the present invention, where the data synchronization method for the electroencephalogram device and the data synchronization method for the electroencephalogram device according to the above embodiments belong to the same inventive concept, and details that are not described in detail in this embodiment may refer to an embodiment of the data synchronization method for the electroencephalogram device. As shown in fig. 4, the data synchronization method for an electroencephalogram device according to an embodiment of the present invention includes:
step 311, the central processing system sends a preparation start synchronization command to the tag subsystem and the acquisition subsystem through the first wireless communication protocol.
Step 312, the tagging subsystem and the acquisition subsystem respond to the central processing system with a ready to complete command based on the ready to begin synchronization command.
Step 313, the central processing system determines the marking subsystem and the acquisition subsystem to complete preparation and start synchronization according to the preparation completion instruction, and sends a synchronization instruction to the marking subsystem and the acquisition subsystem through the first wireless communication protocol, so that the marking subsystem resets the time stamp according to the synchronization instruction and the acquisition subsystem resets the time stamp according to the synchronization instruction.
Step 314, the central processing system sends a synchronous query command to at least one acquisition subsystem and the tag subsystem simultaneously via the first wireless communication protocol.
Wherein, after the marking subsystem 20 resets its time stamp according to the synchronization instruction and the collecting subsystem 30 resets its time stamp according to the synchronization instruction, the central processing system 10 sends a synchronization query instruction to at least one collecting subsystem 30 and the marking subsystem 20 through the first wireless communication protocol to determine whether the time stamp of the at least one collecting subsystem 30 and the time stamp of the marking subsystem 20 are consistent.
Step 315, the collection subsystem responds to the central processing system with the first initial timestamp according to the synchronous query instruction, and the tagging subsystem responds to the central processing system with the second initial timestamp according to the synchronous query instruction.
Wherein the acquisition subsystem 30 and the tagging subsystem 20 reply to the central processing system 10 via UDP. For example, the acquisition subsystem 30 and the tagging subsystem 20 both reply to the central processing system 10 with a time, i.e., a start time, at the same time through UDP, wherein the time when the acquisition subsystem 30 replies to the central processing system 10 according to the synchronous query command is a first time stamp, and the time when the tagging subsystem 20 replies to the central processing system 10 according to the synchronous query command is a second initial time stamp.
Step 316, the central processing system determines whether the difference between the first initial timestamp and the second initial timestamp is within a first preset range.
Step 317, if the difference value of the first initial timestamp and the second initial timestamp is within a first preset range, completing the synchronization of the marking subsystem and the acquisition subsystem;
step 318, if the difference value between the first initial timestamp and the second initial timestamp is not within the first preset range, returning to step 313 until the difference value between the first initial timestamp and the second initial timestamp is within the first preset range.
For example, if the current time of the acquisition subsystem 30 is 1s and the current time of the marking subsystem 20 is 1.1s, the difference is small enough to indicate that the marking subsystem 20 and the acquisition subsystem 30 are synchronized. If the current time of the acquisition subsystem 30 is 1s, and the current time of the marking subsystem 20 is 2s, it indicates that the synchronization is not good, and the resynchronization is needed until the difference between the first initial timestamp and the second initial timestamp is within the first preset range.
Step 320, the acquisition subsystem acquires data information and transmits the data information at a preset frequency, adds a first time stamp corresponding to the data information into a data packet, transmits the data packet and the data information to the central processing system, and simultaneously transmits a second time stamp at a time corresponding to an event occurrence signal according to the event occurrence signal transmitted by the central processing system through a wired communication protocol; wherein the data information in the data packet comprises consecutive 1 st signal data point, …, i-1 st signal data point and i signal data point, i is a positive integer; .
And step 330, the central processing system receives the data packet sent by the acquisition subsystem through the second wireless communication protocol, acquires a current second timestamp from the marking subsystem through the wired communication protocol, the first wireless communication protocol or the second wireless communication protocol, and aligns a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem.
Optionally, fig. 5 is a schematic structural diagram of another electroencephalogram device provided in an embodiment of the present invention, and as shown in fig. 5, the central processing system 10 provided in the embodiment of the present invention includes a data processing module 11, a first wired communication module 12, and a first wireless communication module 13. The tag subsystem 20 includes a second wired communication module 21 and a second wireless communication module 22; the acquisition subsystem 30 comprises a data acquisition processing module 31 and a network communication module 32; the first wired communication module 12 is used for establishing a wired connection with the second wired communication module 21 through a wired communication protocol; the first wireless communication module 13 is configured to establish a wireless network connection with the second wireless communication module 22 through a first wireless communication protocol; and is further configured to establish a wireless network connection with the network communication module 32 via the first wireless communication protocol and the second wireless communication protocol; the data processing module 11 is configured to send an instruction to the marking subsystem 20 and the collecting subsystem 30 through a first wireless communication module in the central processing system 10 in a first wireless communication protocol, so as to complete synchronization of the marking subsystem 20 and the collecting subsystem 30; the data acquisition processing module 31 is configured to acquire data information and transmit the data information at a preset frequency, add a first timestamp corresponding to the data information to a data packet, send the data packet to the data processing module 11 together with the data information, and simultaneously send a second timestamp at a time corresponding to an event occurrence signal according to the event occurrence signal transmitted by the data processing module 11 through a wired communication protocol by the tagging subsystem 20; the data processing module 11 is further configured to receive a data packet sent by the acquisition subsystem 30 through a second wireless communication protocol, acquire a current second timestamp from the marking subsystem 20 through the wired communication protocol, the first wireless communication protocol, or the second wireless communication protocol, and align a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem 20.
That is, the functions of the data processing module 11 include internal trigger event generation, data reception, alignment and processing of data and event. The first wireless communication module 13 in the central processing system 10 establishes a wireless network connection with the second wireless communication module 22 in the marking subsystem 20 and the network communication module 32 in the acquisition subsystem 30 through the first wireless communication protocol for timestamp alignment control. The first wired communication module 12 in the central processing system 10 and the second wired communication module 21 in the tag subsystem 20 establish a wired connection through a wired communication protocol to transmit the trigger event signal generated by the data processing module 11 to the tag subsystem 20 through the wired communication protocol, thereby avoiding the problem of delay. The first wireless communication module 13 in the central processing system 10 establishes a wireless network connection with the network communication module 32 in the acquisition subsystem 30 through a second wireless communication protocol, so that the data acquired by the data processing module 31 in the acquisition subsystem 30 according to the set sampling frequency is sent to the data processing module 11. The data processing module 11 obtains a current second timestamp from the marking subsystem according to the received data packet and through the wired communication protocol, the first wireless communication protocol or the second wireless communication protocol, and performs alignment of a data point corresponding to the second timestamp. In addition, the acquisition subsystem 30 and the tag subsystem 20 may communicate with each other via a first wireless communication protocol, which is a broadcast communication protocol and only receives and sends data without interaction.
It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.

Claims (10)

1. The data synchronization method of the electroencephalogram device is characterized in that the electroencephalogram device comprises a central processing system, a marking subsystem and at least one acquisition subsystem;
the data synchronization method of the electroencephalogram device comprises the following steps:
the central processing system sends an instruction to the marking subsystem and the acquisition subsystem through a first wireless communication protocol so as to complete the synchronization of the marking subsystem and the acquisition subsystem;
the acquisition subsystem acquires data information and transmission data information at a preset frequency, adds a first time stamp corresponding to the data information into a data packet, and sends the data packet and the data information to the central processing system, and meanwhile, the marking subsystem sends a second time stamp at a corresponding moment of an event occurrence signal according to the event occurrence signal transmitted by the central processing system through a wired communication protocol; wherein the data information in the data packet comprises consecutive 1 st signal data point, …, i-1 st signal data point and i signal data point, i is a positive integer;
and the central processing system receives the data packet sent by the acquisition subsystem through a second wireless communication protocol, acquires a current second timestamp from the marking subsystem through the wired communication protocol, the first wireless communication protocol or the second wireless communication protocol, and aligns a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem.
2. The data synchronization method of an electroencephalographic apparatus according to claim 1, wherein the first time stamp includes:
…, a 1 st sampling time point corresponding to the 1 st signal data point, an i-1 st sampling time point corresponding to the i-1 st signal data point, and an i-th sampling time point corresponding to the i-th signal data point; alternatively, the first and second electrodes may be,
sequence numbers 1 and … corresponding to the 1 st signal data point, sequence number 2 corresponding to the i-1 st signal data point, and sequence number i corresponding to the i-th signal data point.
3. The data synchronization method of an electroencephalograph according to claim 1, wherein the central processing system sends instructions to the tagging subsystem and the acquisition subsystem through a first wireless communication protocol, comprising:
step 111, the central processing system sends a preparation start synchronization instruction to the marking subsystem and the acquisition subsystem through a first wireless communication protocol;
step 112, the marking subsystem and the collecting subsystem respond to the central processing system according to the preparation starting synchronous instruction to prepare a finishing instruction;
and step 113, the central processing system determines the marking subsystem and the acquisition subsystem to complete preparation and start synchronization according to the preparation completion instruction, and sends a synchronization instruction to the marking subsystem and the acquisition subsystem through the first wireless communication protocol, so that the marking subsystem resets the time stamp according to the synchronization instruction and the acquisition subsystem resets the time stamp according to the synchronization instruction.
4. The data synchronization method for electroencephalographic apparatuses according to claim 3, further comprising, after the step 113:
the central processing system sends a synchronous query instruction to the at least one acquisition subsystem and the marking subsystem simultaneously through a first wireless communication protocol;
the acquisition subsystem responds a first initial timestamp to the central processing system at the moment according to the synchronous query instruction, and the marking subsystem responds a second initial timestamp to the central processing system at the moment according to the synchronous query instruction;
the central processing system judges whether the difference value of the first initial timestamp and the second initial timestamp is within a first preset range;
and if the difference value of the first initial timestamp and the second initial timestamp is within a first preset range, completing the synchronization of the marking subsystem and the acquisition subsystem.
5. The method for data synchronization of electroencephalogram devices according to claim 4, wherein if the difference value of the first initial timestamp and the second initial timestamp is not within the first preset range, the step 113 is returned until the difference value of the first initial timestamp and the second initial timestamp is within the first preset range.
6. The data synchronization method of an electroencephalographic device according to claim 1, wherein the marking subsystem comprises a first chip, the acquisition subsystem comprises a second chip;
the first chip and the second chip are of the same chip type.
7. The data synchronization method of the electroencephalogram device according to claim 1, wherein the acquisition subsystem comprises at least one of an electroencephalogram acquisition device, an electromyogram acquisition device and an electrocardiograph acquisition device;
the data information comprises an electroencephalogram signal, an electromyogram signal or an electrocardiosignal.
8. The data synchronization method of the electroencephalograph according to claim 1, wherein the wired communication protocol comprises one of TTL, SDIO protocol, parallel port communication, serial port communication, USB protocol, and HMDI protocol;
the first wireless communication protocol includes: UDP protocol or ICMP protocol;
the second wireless communication protocol includes: TCP/IP protocol.
9. A brain electrical device for implementing a data synchronization method of the brain electrical device according to any one of claims 1 to 8, the brain electrical device comprising: the system comprises a central processing system, a marking subsystem and at least one acquisition subsystem;
the central processing system is used for sending instructions to the marking subsystem and the acquisition subsystem through a first wireless communication protocol so as to complete the synchronization of the marking subsystem and the acquisition subsystem;
the acquisition subsystem is used for acquiring data information and transmitting the data information at a preset frequency, adding a first time stamp corresponding to the data information into a data packet, and sending the data packet and the data information to the central processing system; wherein the data information in the data packet comprises consecutive 1 st signal data point, …, i-1 st signal data point and i signal data point, i is a positive integer;
the marking subsystem is used for sending a second timestamp of a corresponding moment of an event occurrence signal according to the event occurrence signal transmitted by the central processing system through a wired communication protocol;
the central processing system is further configured to receive a data packet sent by the acquisition subsystem through a second wireless communication protocol, acquire a current second timestamp from the marking subsystem through the wired communication protocol, the first wireless communication protocol, or the second wireless communication protocol, and align a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem.
10. The brain electrical device according to claim 9, wherein the central processing system includes a data processing module, a first wired communication module and a first wireless communication module;
the marking subsystem comprises a second wired communication module and a second wireless communication module;
the acquisition subsystem comprises a data acquisition processing module and a network communication module;
the first wired communication module is used for establishing wired connection with the second wired communication module through a wired communication protocol;
the first wireless communication module is used for establishing wireless network connection with the second wireless communication module through a first wireless communication protocol; the wireless network communication module is also used for establishing wireless network connection with the network communication module through a first wireless communication protocol and a second wireless communication protocol;
the data processing module is used for sending instructions to the marking subsystem and the acquisition subsystem through the first wireless communication module in the central processing system in the first wireless communication protocol so as to complete the synchronization of the marking subsystem and the acquisition subsystem;
the data acquisition processing module is used for acquiring data information and transmitting the data information at a preset frequency, adding a first time stamp corresponding to the data information into a data packet, transmitting the data packet and the data information to the data processing module, and meanwhile, the marking subsystem transmits a second time stamp at a corresponding moment of an event occurrence signal according to the event occurrence signal transmitted by the data processing module through the wired communication protocol;
the data processing module is further configured to receive a data packet sent by the acquisition subsystem through the second wireless communication protocol, acquire a current second timestamp from the marking subsystem through the wired communication protocol, the first wireless communication protocol, or the second wireless communication protocol, and align a data point corresponding to the second timestamp according to the second timestamp acquired from the marking subsystem.
CN202110482597.8A 2021-04-30 2021-04-30 Data synchronization method of electroencephalogram device and electroencephalogram device Active CN113143290B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110482597.8A CN113143290B (en) 2021-04-30 2021-04-30 Data synchronization method of electroencephalogram device and electroencephalogram device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110482597.8A CN113143290B (en) 2021-04-30 2021-04-30 Data synchronization method of electroencephalogram device and electroencephalogram device

Publications (2)

Publication Number Publication Date
CN113143290A true CN113143290A (en) 2021-07-23
CN113143290B CN113143290B (en) 2024-01-19

Family

ID=76873200

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110482597.8A Active CN113143290B (en) 2021-04-30 2021-04-30 Data synchronization method of electroencephalogram device and electroencephalogram device

Country Status (1)

Country Link
CN (1) CN113143290B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116236205A (en) * 2022-12-19 2023-06-09 天津大学 Multichannel miniature brain electricity acquisition system
CN116991201A (en) * 2023-09-27 2023-11-03 博睿康科技(常州)股份有限公司 Single-equipment multi-physiological-parameter synchronization method, acquisition system and data alignment method

Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090318785A1 (en) * 2008-06-23 2009-12-24 Akihiro Ishikawa Real - time simultaneous measurement system, real - time simultaneous measurement apparatus, real-time simultaneous measurement method, and storage medium in which program is stored
US20110282232A1 (en) * 2010-05-12 2011-11-17 Neurofocus, Inc. Neuro-response data synchronization
CN102547969A (en) * 2012-02-24 2012-07-04 电子科技大学 High-accuracy wireless clock synchronization system for power system
FR2989240A1 (en) * 2012-04-10 2013-10-11 Commissariat Energie Atomique DATA SYNCHRONIZATION METHOD AND DATA TRANSMISSION SYSTEM USING SUCH A METHOD.
US20140012509A1 (en) * 2012-07-06 2014-01-09 Daniel Barber Methods and systems for synchronization and distribution of multiple physiological and performance measures
US20150358096A1 (en) * 2013-01-14 2015-12-10 Yu Mike Chi Synchronizing wireless data acquisition of physiological information
CN204884122U (en) * 2015-07-13 2015-12-16 北京视友科技有限责任公司 Portable many human brains electricity data synchronous sampling system based on radio communication
CN106332268A (en) * 2016-08-31 2017-01-11 博睿康科技(常州)股份有限公司 Method for precisely synchronizing wireless data of electroencephalogram device
US20170020406A1 (en) * 2012-04-13 2017-01-26 UE Technology Method for measuring biological stimulus signal
CN106361322A (en) * 2016-08-31 2017-02-01 博睿康科技(常州)股份有限公司 Automatic accumulative deviation detection method and automatic accumulative deviation detection device for electroencephalogram device
CN107644566A (en) * 2017-08-17 2018-01-30 北京航空航天大学 A kind of brain electricity evaluation system of the simulated flight device based on brain electricity
CN107874756A (en) * 2017-11-21 2018-04-06 博睿康科技(常州)股份有限公司 The precise synchronization method of eeg collection system and video acquisition system
CN108369646A (en) * 2015-07-16 2018-08-03 博拉斯特运动有限公司 Multisensor event detection and tagging system
CN109756744A (en) * 2017-11-02 2019-05-14 腾讯科技(深圳)有限公司 Data processing method, electronic equipment and computer storage medium
CN110072278A (en) * 2019-04-30 2019-07-30 南京大学 A kind of wireless multinode physiological signal monitor system based on low-power consumption bluetooth
CN110141231A (en) * 2019-05-17 2019-08-20 天津大学 A kind of event time point synchronous recording method in wireless brain wave acquisition
CN110868269A (en) * 2020-01-19 2020-03-06 上海高仙自动化科技发展有限公司 Method and device for determining synchronization between sensors, electronic equipment and storage medium
CN111095860A (en) * 2017-10-30 2020-05-01 华为技术有限公司 Method and device for clock synchronization
CN111360809A (en) * 2018-12-25 2020-07-03 深圳市优必选科技有限公司 Signal instruction control method and device of robot and terminal equipment
CN111885569A (en) * 2020-07-13 2020-11-03 深兰人工智能芯片研究院(江苏)有限公司 Visual stimulation and response acquisition control system

Patent Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090318785A1 (en) * 2008-06-23 2009-12-24 Akihiro Ishikawa Real - time simultaneous measurement system, real - time simultaneous measurement apparatus, real-time simultaneous measurement method, and storage medium in which program is stored
US20110282232A1 (en) * 2010-05-12 2011-11-17 Neurofocus, Inc. Neuro-response data synchronization
CN102547969A (en) * 2012-02-24 2012-07-04 电子科技大学 High-accuracy wireless clock synchronization system for power system
FR2989240A1 (en) * 2012-04-10 2013-10-11 Commissariat Energie Atomique DATA SYNCHRONIZATION METHOD AND DATA TRANSMISSION SYSTEM USING SUCH A METHOD.
US20170020406A1 (en) * 2012-04-13 2017-01-26 UE Technology Method for measuring biological stimulus signal
US20140012509A1 (en) * 2012-07-06 2014-01-09 Daniel Barber Methods and systems for synchronization and distribution of multiple physiological and performance measures
US20150358096A1 (en) * 2013-01-14 2015-12-10 Yu Mike Chi Synchronizing wireless data acquisition of physiological information
CN204884122U (en) * 2015-07-13 2015-12-16 北京视友科技有限责任公司 Portable many human brains electricity data synchronous sampling system based on radio communication
CN108369646A (en) * 2015-07-16 2018-08-03 博拉斯特运动有限公司 Multisensor event detection and tagging system
CN106332268A (en) * 2016-08-31 2017-01-11 博睿康科技(常州)股份有限公司 Method for precisely synchronizing wireless data of electroencephalogram device
CN106361322A (en) * 2016-08-31 2017-02-01 博睿康科技(常州)股份有限公司 Automatic accumulative deviation detection method and automatic accumulative deviation detection device for electroencephalogram device
CN107644566A (en) * 2017-08-17 2018-01-30 北京航空航天大学 A kind of brain electricity evaluation system of the simulated flight device based on brain electricity
CN111095860A (en) * 2017-10-30 2020-05-01 华为技术有限公司 Method and device for clock synchronization
CN109756744A (en) * 2017-11-02 2019-05-14 腾讯科技(深圳)有限公司 Data processing method, electronic equipment and computer storage medium
CN107874756A (en) * 2017-11-21 2018-04-06 博睿康科技(常州)股份有限公司 The precise synchronization method of eeg collection system and video acquisition system
CN111360809A (en) * 2018-12-25 2020-07-03 深圳市优必选科技有限公司 Signal instruction control method and device of robot and terminal equipment
CN110072278A (en) * 2019-04-30 2019-07-30 南京大学 A kind of wireless multinode physiological signal monitor system based on low-power consumption bluetooth
CN110141231A (en) * 2019-05-17 2019-08-20 天津大学 A kind of event time point synchronous recording method in wireless brain wave acquisition
CN110868269A (en) * 2020-01-19 2020-03-06 上海高仙自动化科技发展有限公司 Method and device for determining synchronization between sensors, electronic equipment and storage medium
CN111885569A (en) * 2020-07-13 2020-11-03 深兰人工智能芯片研究院(江苏)有限公司 Visual stimulation and response acquisition control system

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116236205A (en) * 2022-12-19 2023-06-09 天津大学 Multichannel miniature brain electricity acquisition system
CN116991201A (en) * 2023-09-27 2023-11-03 博睿康科技(常州)股份有限公司 Single-equipment multi-physiological-parameter synchronization method, acquisition system and data alignment method
CN116991201B (en) * 2023-09-27 2023-12-22 博睿康科技(常州)股份有限公司 Single-equipment multi-physiological-parameter synchronization method, acquisition system and data alignment method

Also Published As

Publication number Publication date
CN113143290B (en) 2024-01-19

Similar Documents

Publication Publication Date Title
CN113143290B (en) Data synchronization method of electroencephalogram device and electroencephalogram device
CN110141231B (en) Event time point synchronous recording method in wireless electroencephalogram acquisition
DE60132665T2 (en) WIRELESS SYSTEM PROTOCOL FOR TELEMETRY MONITORING
CN103607269B (en) A kind of brain electric installation and accurate wireless event synchronizing method
US20090185548A1 (en) Enhanced communication of data in wireless control area networks
CN104287726B (en) A kind of cerebration event synchronization record system and method
EP2158841A2 (en) Synchronization of medical devices via digital interface
DE102005029439A1 (en) Add-on module for synchronizing operations of a plurality of devices
CN107874756A (en) The precise synchronization method of eeg collection system and video acquisition system
CN109217961A (en) A kind of multimodal human-computer interaction and man-machine environment test data synchronizing device and method
CN110072278A (en) A kind of wireless multinode physiological signal monitor system based on low-power consumption bluetooth
US20140128735A1 (en) Wireless real-time electrocardiogram and medical image integration
CN110739969A (en) signal synchronous acquisition system
CN112804022B (en) Multi-source signal synchronization system and method thereof
CN107898457B (en) Method for clock synchronization between group wireless electroencephalogram acquisition devices
CN113288178B (en) Electroencephalogram event synchronization system and method based on multi-channel electroencephalogram acquisition
EP1227691B1 (en) Distributed test system for testing and monitoring electronic signals on network connections
CN113180698B (en) Wireless automatic deviation compensation method of electroencephalogram device and electroencephalogram device
DE112014000420T5 (en) Synchronize wireless data collection of physiological information
US20130293393A1 (en) Data Synchronization Method and Data Transmission System to Carry out Such a Method
CN102749864A (en) Bridge acceleration signal conditioner
DE102020118068A1 (en) SYNCHRONIZATION OF A NETWORK DEVICE FOR WIRELESS COMMUNICATION, IN PARTICULAR A NETWORK TERMINAL DEVICE, IN A WIRELESS NETWORK
CN116991201B (en) Single-equipment multi-physiological-parameter synchronization method, acquisition system and data alignment method
CN211127817U (en) Synchronous module
CN113541846B (en) Method and system for monitoring network time synchronization performance

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant