CN113116382A - Skin tissue temperature detection device and detection method - Google Patents
Skin tissue temperature detection device and detection method Download PDFInfo
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- CN113116382A CN113116382A CN201911399428.7A CN201911399428A CN113116382A CN 113116382 A CN113116382 A CN 113116382A CN 201911399428 A CN201911399428 A CN 201911399428A CN 113116382 A CN113116382 A CN 113116382A
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- 238000001514 detection method Methods 0.000 title abstract description 29
- 238000012545 processing Methods 0.000 claims abstract description 14
- 230000008859 change Effects 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 16
- 238000002604 ultrasonography Methods 0.000 claims description 15
- 238000002560 therapeutic procedure Methods 0.000 description 7
- 238000002595 magnetic resonance imaging Methods 0.000 description 6
- 230000008569 process Effects 0.000 description 5
- 206010028851 Necrosis Diseases 0.000 description 3
- 206010046798 Uterine leiomyoma Diseases 0.000 description 3
- 238000009529 body temperature measurement Methods 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 230000001112 coagulating effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000017074 necrotic cell death Effects 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000012886 linear function Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0858—Detecting organic movements or changes, e.g. tumours, cysts, swellings involving measuring tissue layers, e.g. skin, interfaces
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N7/02—Localised ultrasound hyperthermia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0052—Ultrasound therapy using the same transducer for therapy and imaging
Abstract
The invention provides a skin tissue temperature detection device and a skin tissue temperature detection method, belongs to the technical field of temperature detection, and can solve the problem that the existing skin tissue temperature detection time period is long. The skin tissue temperature detection device of the present invention includes: the signal receiving and transmitting module comprises a signal transmitting unit and a signal receiving unit, wherein the signal transmitting unit is used for transmitting ultrasonic signals to skin tissues to be detected; the signal receiving unit is used for receiving a reflected ultrasonic signal reflected by the skin tissue and determining parameters of the reflected ultrasonic signal; and the processing module is used for determining the temperature of the skin tissue according to the parameters of the reflected ultrasonic signals and the corresponding relationship between the pre-stored parameters of the reflected ultrasonic signals and the skin temperature.
Description
Technical Field
The invention belongs to the technical field of temperature detection, and particularly relates to a device and a method for detecting the temperature of skin tissues.
Background
The High Intensity Focused Ultrasound (HIFU) technology focuses ultrasonic energy propagated in a biological tissue through a focused ultrasound transducer to form a high intensity focal point, and the temperature of the focal point rapidly rises to over 65 ℃ after the focal point absorbs strong acoustic energy, so that the biological tissue in the focal point range achieves coagulation necrosis, and the biological tissue outside the acoustic wave focusing region is not lost, thereby realizing non-invasive treatment on human tumors or diseased tissues.
In the HIFU ultrasonic surgical procedures for treating hysteromyoma and the like using HIFU technology, the temperature of skin tissue needs to be detected. At present, the detection of skin tissue temperature is mainly based on MRI (Magnetic Resonance Imaging), but if MRI is used for monitoring the temperature change in operations such as the treatment of hysteromyoma by HIFU, the temperature measurement result cannot be obtained immediately, the operation needs to wait for about 5-10s, if temperature detection is carried out for multiple times in the operations, the operation time is greatly prolonged, and the MRI is difficult to popularize due to high cost.
Disclosure of Invention
The present invention is directed to at least one of the technical problems of the prior art, and provides a temperature detection device for skin tissue capable of rapidly detecting the temperature of the skin tissue.
The technical scheme adopted for solving the technical problem of the invention is a skin tissue temperature detection device, which comprises:
the signal receiving and transmitting module comprises a signal transmitting unit and a signal receiving unit, wherein the signal transmitting unit is used for transmitting ultrasonic signals to skin tissues to be detected; the signal receiving unit is used for receiving a reflected ultrasonic signal reflected by the skin tissue and determining parameters of the reflected ultrasonic signal;
and the processing module is used for determining the temperature of the skin tissue according to the parameters of the reflected ultrasonic signals and the corresponding relationship between the pre-stored parameter change of the reflected ultrasonic signals and the skin temperature.
Preferably, the signal transceiving module comprises a focused ultrasound transducer.
Preferably, the ultrasonic signal comprises a focused pulsed ultrasonic signal.
Preferably, the parameter of the reflected ultrasonic signal comprises an amplitude of the reflected ultrasonic signal;
the device for detecting the temperature of the skin tissue further comprises a storage unit, a processing unit and a control unit, wherein the storage unit is used for storing the corresponding relation between the amplitude change of the reflected ultrasonic signal and the skin temperature;
the processing module is specifically configured to determine the temperature of the skin tissue according to the amplitude of the reflected ultrasonic signal and the corresponding relationship between the amplitude change of the reflected ultrasonic signal and the skin temperature.
The technical scheme adopted for solving the technical problem of the invention is a skin tissue temperature detection method, which comprises the following steps:
transmitting an ultrasonic signal to skin tissue to be detected;
receiving a reflected ultrasonic signal reflected by the skin tissue and determining parameters of the reflected ultrasonic signal;
and determining the temperature of the skin tissue according to the parameters of the reflected ultrasonic signals and the corresponding relationship between the pre-stored parameter change of the reflected ultrasonic signals and the skin temperature.
Preferably, the ultrasonic signal comprises a focused pulsed ultrasonic signal.
Preferably, the parameters of the reflected ultrasonic signal include: the amplitude of the reflected ultrasonic signal;
the step of determining the temperature of the skin tissue according to the pre-stored correspondence of the parameters of the reflected ultrasound signal to the skin temperature, based on the parameters of the reflected ultrasound signal, comprises: and determining the temperature of the skin tissue according to the amplitude of the reflected ultrasonic signal and the corresponding relation between the pre-stored amplitude change of the reflected ultrasonic signal and the skin temperature.
Preferably, the correspondence relationship between the amplitude variation of the reflected ultrasonic signal and the skin temperature includes: the corresponding function relation of the amplitude of the reflected ultrasonic signal and the skin temperature.
Drawings
Fig. 1 is a block diagram of a skin tissue temperature detection apparatus according to embodiment 1 of the present invention;
fig. 2 is a flowchart of a method for detecting the temperature of skin tissue according to embodiment 2 of the present invention.
Detailed Description
In order to make the technical solutions of the present invention better understood, the present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.
In the HIFU ultrasonic surgical procedures for treating hysteromyoma and the like using HIFU technology, the temperature of skin tissue needs to be detected. At present, the skin tissue temperature detection mode is mainly MRI, but MRI detection cost is high, measurement precision of a high-temperature area is inaccurate, a temperature measurement result cannot be obtained immediately, waiting for about 5-10s is needed, and operation time is greatly prolonged if temperature detection is carried out for multiple times in an operation. Embodiments of the present invention provide a device and a method for detecting a temperature of a skin tissue, and the device and the method for detecting a temperature of a skin tissue according to embodiments of the present invention will be described in detail below with reference to the following detailed description and accompanying drawings.
Example 1:
as shown in fig. 1, the present embodiment provides a temperature detection apparatus for skin tissue, including: the device comprises a signal transceiving module and a processing module.
The signal receiving and transmitting module comprises a signal transmitting unit and a signal receiving unit, wherein the signal transmitting unit is used for transmitting ultrasonic signals to skin tissues to be detected; the signal receiving unit is used for receiving the reflected ultrasonic signals reflected by the skin tissue and determining the parameters of the reflected ultrasonic signals. The processing module is used for determining the temperature of the skin tissue according to the parameters of the reflected ultrasonic signals and the corresponding relationship between the pre-stored parameters of the reflected ultrasonic signals and the skin temperature.
In the skin temperature detection device provided by this embodiment, the signal transceiver module can transmit the ultrasonic signal to the skin tissue to be detected and receive the returned ultrasonic signal. During HIFU treatment, the temperature of the skin tissue needs to be detected. The inventor finds that the acoustic impedance of the skin tissue is different at different temperatures, which causes the ultrasonic signals reflected by the skin tissue with different temperatures to be different, so that the present temperature of the skin tissue can be determined by detecting the received ultrasonic signals reflected by the skin tissue in the embodiment.
Taking HIFU therapy as an example, as the temperature of the skin surface increases, the acoustic impedance of the skin tissue changes, and the amplitude of the ultrasonic signal reflected by the skin tissue increases. With the temperature increasing, the skin tissue is gradually denatured and coagulative necrosis occurs, which causes the hardness of the skin tissue to change, the ultrasonic signal capable of passing through the skin tissue is reduced, and the amplitude of the reflected ultrasonic signal is increased. The temperature of the skin tissue can thus be determined by detecting the ultrasound signals reflected by the skin tissue.
In this embodiment, the signal transceiver module has functions of transmitting and receiving ultrasonic signals. That is, the signal transceiver module can transmit the ultrasonic signal to the skin tissue, and can also receive and detect the reflected ultrasonic signal reflected by the skin tissue to determine the parameters of the reflected ultrasonic signal. The parameters of the ultrasonic signal may include the amplitude, intensity, etc. of the ultrasonic signal.
Preferably, the ultrasonic signal comprises a focused pulsed ultrasonic signal.
Preferably, the signal transceiving module comprises a focused ultrasound transducer. The focusing ultrasonic transducer is a mature device integrating the functions of ultrasonic emission and ultrasonic receiving. The focusing ultrasonic transducer is provided with a signal transmitting unit and a signal receiving unit, wherein the signal transmitting unit can transmit focusing pulse ultrasonic signals and can specifically transmit the focusing pulse ultrasonic signals to skin tissues to be subjected to temperature detection; the signal receiving unit may receive the focused pulsed ultrasound signal reflected by the skin tissue (i.e. the reflected ultrasound signal) for determining the temperature of the skin tissue from the reflected ultrasound signal. In this embodiment, an ultrasonic transducer with a mature technology in the prior art can be directly selected as the signal transceiver module. Of course, other devices capable of implementing the functions of transmitting and receiving the ultrasonic signal may be selected, which is not limited in this embodiment.
Preferably, the present embodiment further comprises a storage unit, which is used for storing the corresponding relationship between the parameter variation of the reflected ultrasonic signal and the skin temperature. The corresponding relationship between the parameter variation of the reflected ultrasonic signal and the skin temperature may include a corresponding functional relationship between the amplitude of the parameter of the reflected ultrasonic signal and the skin temperature. Specifically, multiple experiments can be performed in advance, a thermocouple is attached to the surface of skin tissue to record the temperature of the surface of the skin according to the sizes of relevant parameters of reflected ultrasonic signals at different temperatures, two groups of data corresponding to the amplitude of the parameter of the reflected ultrasonic signal and the skin temperature are obtained through multiple experiments, linear fitting is performed on the two groups of data to obtain a unitary linear function relation, and the function relation is continuously optimized (multiple groups of data are measured to obtain an average value); after the relation is determined, the amplitude values in a group of data which are not calculated are substituted into the function relation to calculate the temperature, the temperature is compared with experimental data measured by a thermocouple, and if the difference between the calculated temperature and the measured temperature is not large, the function relation can be used for monitoring the data processing of the skin tissue temperature in the HIFU treatment process.
Or, the corresponding relationship between the parameter variation of the reflected ultrasonic signal and the skin temperature may also include a corresponding table of the parameter amplitude of the reflected ultrasonic signal and the skin temperature, and similarly, the parameter amplitude of the reflected ultrasonic signal at different skin temperatures may be determined through multiple experiments, and multiple sets of corresponding data of the parameter amplitude of the reflected ultrasonic signal and the skin temperature with smaller error may be obtained after data processing through multiple times of test data, so as to be used for detecting the skin tissue temperature.
Preferably, in this embodiment, the parameter of the reflected ultrasonic signal includes an amplitude of the reflected ultrasonic signal. Experimental data prove that the amplitude change of the ultrasonic signals reflected by the skin tissue at different temperatures is relatively more obvious, so that the temperature of the skin tissue is preferably detected by detecting the amplitude of the reflected ultrasonic signals in the embodiment.
Specifically, when the parameter of the reflected ultrasonic signal includes the amplitude of the reflected ultrasonic signal, the storage unit may be configured to store a correspondence between a change in the amplitude of the reflected ultrasonic signal and the skin temperature. The processing module is specifically used for determining the temperature of the skin tissue according to the amplitude of the reflected ultrasonic signal and the corresponding relation between the amplitude of the reflected ultrasonic signal and the skin temperature.
In the device for detecting the temperature of the skin tissue provided by the embodiment, the processing module can be realized by a device with a data processing function, such as a chip processor and a computer, and through setting of a program, the temperature of the skin tissue can be determined according to the parameters of the reflected ultrasonic signals and the corresponding relation between the parameter change of the pre-stored reflected ultrasonic signals and the skin temperature.
Example 2:
as shown in fig. 2, the present embodiment provides a method for detecting a temperature of skin tissue, which can detect a temperature of skin tissue based on the device for detecting a temperature of skin tissue provided in embodiment 1. The detection method can comprise the following steps:
s1, transmitting an ultrasonic signal to the skin tissue to be detected.
Preferably, the ultrasonic signal includes a pulsed ultrasonic signal.
S2, receiving the reflected ultrasonic wave signal reflected by the skin tissue and determining the parameters of the reflected ultrasonic wave signal.
Preferably, the parameters of the reflected ultrasonic signal include: the amplitude of the reflected ultrasonic signal. In this step, the method may specifically include: and determining the temperature of the skin tissue according to the amplitude of the reflected ultrasonic signal and the corresponding relation between the pre-stored amplitude of the reflected ultrasonic signal and the skin temperature.
And S3, determining the temperature of the skin tissue according to the parameters of the reflected ultrasonic signals and the corresponding relationship between the pre-stored parameters of the reflected ultrasonic signals and the skin temperature.
Preferably, when the parameters of the reflected ultrasonic signal include: when the amplitude of the reflected ultrasonic signal is larger than the corresponding value of the skin temperature, the corresponding relation between the amplitude of the reflected ultrasonic signal and the skin temperature comprises the following steps: the corresponding function relation between the amplitude change of the reflected ultrasonic signal and the skin temperature.
In the skin temperature detection method provided by this embodiment, the signal transceiver module may transmit an ultrasonic signal to the skin tissue to be detected and receive a returned ultrasonic signal. By detecting the received ultrasonic signals reflected by the skin tissue, the current temperature of the skin tissue can be determined. The skin temperature detection method provided by the embodiment is low in cost, and can realize real-time temperature measurement, namely, if the temperature changes, the temperature can be displayed immediately.
Taking HIFU therapy as an example, as the temperature of the skin surface increases, the acoustic impedance of the skin tissue changes, and the amplitude of the ultrasonic signal reflected by the skin tissue increases. With the temperature increasing, the skin tissue is gradually denatured and coagulative necrosis occurs, which causes the hardness of the skin tissue to change, the ultrasonic signal capable of passing through the skin tissue is reduced, and the amplitude of the reflected ultrasonic signal is increased. The temperature of the skin tissue can thus be determined by detecting the ultrasound signals reflected by the skin tissue. The method for detecting the temperature of the skin tissue based on the embodiment can shorten the detection time of the skin tissue, thereby shortening the operation time, and can reflect the temperature of the skin in time in the operation process so as to prevent the skin from being scalded in the HIFU treatment.
Specifically, when the temperature detection method provided by this embodiment is used in HIFU therapy, the temperature detection method may be combined with HIFU therapy equipment and used in a HIFU therapy process; for example, in the process of stopping 2 seconds for 2S-5 cycles (HIFU therapy for 2 seconds, stopping 2 seconds, and HIFU therapy for 5 cycles), a signal transceiver module transmits a pulse ultrasonic signal (e.g., focused pulse ultrasonic) and then receives a reflected ultrasonic signal, and the change of the skin surface temperature is determined by the amplitude of the reflected ultrasonic signal reflected by the skin surface, so that the skin temperature is monitored during the treatment process without affecting the treatment, and a real-time monitoring effect is achieved. The technology can realize the transmission of ultrasonic signals and the reception and detection of the amplitude of the reflected ultrasonic waves through software, does not need manual operation after being combined with the HIFU equipment, and automatically calculates the corresponding temperature through the amplitude, thereby facilitating the judgment of a doctor on the treatment effect. The signal transceiver module and the therapeutic head of HIFU treatment can use the same ultrasonic transducer, and only needs to convert and transmit the corresponding required signal, thereby saving the cost of the therapeutic equipment.
It will be understood that the above embodiments are merely exemplary embodiments taken to illustrate the principles of the present invention, which is not limited thereto. It will be apparent to those skilled in the art that various modifications and improvements can be made without departing from the spirit and substance of the invention, and these modifications and improvements are also considered to be within the scope of the invention.
Claims (8)
1. A device for detecting the temperature of skin tissue, comprising:
the signal receiving and transmitting module comprises a signal transmitting unit and a signal receiving unit, wherein the signal transmitting unit is used for transmitting ultrasonic signals to skin tissues to be detected; the signal receiving unit is used for receiving a reflected ultrasonic signal reflected by the skin tissue and determining parameters of the reflected ultrasonic signal;
and the processing module is used for determining the temperature of the skin tissue according to the parameters of the reflected ultrasonic signals and the corresponding relationship between the pre-stored parameter change of the reflected ultrasonic signals and the skin temperature.
2. The device for detecting the temperature of skin tissue according to claim 1, wherein said signal transceiving module comprises a focused ultrasound transducer.
3. The device for detecting the temperature of skin tissue according to claim 1, wherein said ultrasonic signal comprises a focused pulsed ultrasonic signal.
4. The device for detecting the temperature of skin tissue according to claim 1, wherein the parameter of the reflected ultrasonic signal comprises an amplitude of the reflected ultrasonic signal;
the device for detecting the temperature of the skin tissue further comprises a storage unit, a processing unit and a control unit, wherein the storage unit is used for storing the corresponding relation between the amplitude change of the reflected ultrasonic signal and the skin temperature;
the processing module is specifically configured to determine the temperature of the skin tissue according to the amplitude of the reflected ultrasonic signal and the corresponding relationship between the amplitude change of the reflected ultrasonic signal and the skin temperature.
5. A method of detecting temperature of skin tissue, comprising:
transmitting an ultrasonic signal to skin tissue to be detected;
receiving a reflected ultrasonic signal reflected by the skin tissue and determining parameters of the reflected ultrasonic signal;
and determining the temperature of the skin tissue according to the parameters of the reflected ultrasonic signals and the corresponding relationship between the pre-stored parameter change of the reflected ultrasonic signals and the skin temperature.
6. The method for detecting the temperature of skin tissue according to claim 5,
the ultrasonic signal comprises a focused pulsed ultrasonic signal.
7. The method for detecting the temperature of skin tissue according to claim 5, wherein the parameters of the reflected ultrasonic signal include: the amplitude of the reflected ultrasonic signal;
the step of determining the temperature of the skin tissue according to the pre-stored correspondence of the parameters of the reflected ultrasound signal to the skin temperature, based on the parameters of the reflected ultrasound signal, comprises: and determining the temperature of the skin tissue according to the amplitude of the reflected ultrasonic signal and the corresponding relation between the pre-stored amplitude change of the reflected ultrasonic signal and the skin temperature.
8. The method according to claim 7, wherein said correlation of the amplitude variation of the reflected ultrasound signal with the skin temperature comprises: the corresponding function relation of the amplitude of the reflected ultrasonic signal and the skin temperature.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114428527A (en) * | 2022-01-26 | 2022-05-03 | 云南贝泰妮生物科技集团股份有限公司 | Radio frequency beauty instrument temperature control system based on ultrasonic echo |
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