CN113100922B - Radio frequency ablation electrode integrated with optical fiber temperature sensor - Google Patents

Radio frequency ablation electrode integrated with optical fiber temperature sensor Download PDF

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Publication number
CN113100922B
CN113100922B CN202110378981.3A CN202110378981A CN113100922B CN 113100922 B CN113100922 B CN 113100922B CN 202110378981 A CN202110378981 A CN 202110378981A CN 113100922 B CN113100922 B CN 113100922B
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ablation
optical fiber
temperature sensor
electrode
fiber temperature
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CN113100922A (en
Inventor
莫晓龙
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Nuoer Medical Shenzhen Co ltd
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Nuoer Medical Shenzhen Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/0066Sensing and controlling the application of energy without feedback, i.e. open loop control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00666Sensing and controlling the application of energy using a threshold value
    • A61B2018/00678Sensing and controlling the application of energy using a threshold value upper
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00773Sensed parameters
    • A61B2018/00791Temperature
    • A61B2018/00797Temperature measured by multiple temperature sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1467Probes or electrodes therefor using more than two electrodes on a single probe

Abstract

The application provides a radio frequency ablation electrode integrated with a fiber temperature sensor. The radio frequency ablation electrode integrated with the optical fiber temperature sensor comprises a sleeve (7) and the optical fiber temperature sensor. A plurality of ablation recording common electrodes are integrated on the sleeve (7), and comprise a first ablation recording common electrode (31) and a second ablation recording common electrode (32). The optical fiber temperature sensor comprises an optical fiber temperature sensor probe (1), and the optical fiber temperature sensor probe (1) is arranged on the side wall or inside the sleeve (7).

Description

Radio frequency ablation electrode integrated with optical fiber temperature sensor
Technical Field
The application relates to an electrode with a radio frequency ablation function, in particular to a radio frequency ablation electrode integrated with an optical fiber temperature sensor.
Background
Radio frequency ablation is widely used in minimally invasive surgery as a primary thermal ablation means, for example, lesion tissue can be ablated. Taking an intracranial electrode with a radiofrequency ablation function as an example, two electrode contacts are connected with external radiofrequency ablation equipment through a lead. And controlling the electrode contacts to discharge, and forming radio frequency current between the electrode contacts. The tissue in a surrounding area is ablated by taking the middle position of the two electrode contacts as the center.
In order to reasonably control the temperature, temperature sensors such as thermocouples are generally integrated on existing radiofrequency ablation electrodes. However, the conventional temperature sensor is easily interfered by electromagnetic environments such as magnetic resonance and the like, and has no magnetic resonance compatibility.
Disclosure of Invention
In order to solve or improve the problems mentioned in the prior art, the application provides a radio frequency ablation electrode integrated with a fiber optic temperature sensor.
The application provides a radio frequency ablation electrode integrated with a fiber temperature sensor, which comprises a sleeve and the fiber temperature sensor,
a plurality of ablation recording common electrodes are integrated on the sleeve, the plurality of ablation recording common electrodes comprise a first ablation recording common electrode and a second ablation recording common electrode,
the optical fiber temperature sensor comprises an optical fiber temperature sensor probe which is arranged on the side wall or inside the sleeve.
In at least one embodiment, the first ablation recording common electrode and the second ablation recording common electrode are disposed at an end portion of the sleeve at intervals in an axial direction of the sleeve.
In at least one embodiment, the fiber optic temperature sensor probe is located intermediate the first and second ablation-recording common electrodes and the fiber optic temperature sensor probe is located on a sidewall of the cannula.
In at least one embodiment, the fiber optic temperature sensor probe is located intermediate the first and second ablation-recording common electrodes and is located on the axis of the cannula.
In at least one embodiment, the radiofrequency ablation electrode integrated with the fiber optic temperature sensor further comprises an optical fiber and a fiber optic connector,
the optical fiber temperature sensor probe is integrated at the end part of the optical fiber, and the optical fiber temperature sensor probe realizes signal exchange with external equipment through the optical fiber and the optical fiber connector.
In at least one embodiment, the optical fiber is externally sheathed with a protective tube.
In at least one embodiment, the fiber-optic temperature sensor integrated radiofrequency ablation electrode further comprises one or more recording electrodes, and the first ablation recording common electrode, the second ablation recording common electrode and the one or more recording electrodes are arranged on the side wall of the sleeve at equal intervals along the axial direction of the sleeve.
In at least one embodiment, the plurality of ablation recording common electrodes are disposed on a sidewall of the sleeve at intervals along an axial direction of the sleeve,
two adjacent ablation recording common electrodes in the plurality of ablation recording common electrodes form an ablation electrode pair, the radio-frequency ablation electrode integrated with the optical fiber temperature sensor comprises one or more ablation electrode pairs,
the radio frequency ablation electrode integrated with the optical fiber temperature sensor comprises one or more optical fiber temperature sensor probes.
In at least one embodiment, the fiber optic temperature sensor integrated radio frequency ablation electrode comprises a plurality of ablation electrode pairs and a plurality of fiber optic temperature sensor probes,
the plurality of optical fiber temperature sensor probes are respectively arranged in the middle position between two ablation recording common electrodes of the plurality of ablation electrode pairs.
In at least one embodiment, the ablation recording common electrodes arranged at intervals are equally spaced, and a plurality of the fiber-optic temperature sensor probes are respectively arranged at the central positions of the ablation electrode pairs.
In at least one embodiment, the fiber optic temperature sensor integrated radiofrequency ablation electrode comprises a lead for connecting the first and second ablation recording common electrodes to an external radiofrequency ablation device, and radiofrequency ablation is achieved by forming a radiofrequency current between the first and second ablation recording common electrodes.
The optical fiber temperature sensor is integrated in the radio frequency ablation electrode, the traditional thermocouple is replaced, the temperature measurement is met, meanwhile, the optical fiber is used as a transmission carrier of temperature signals, the interference under electromagnetic environments such as magnetic resonance is avoided, and the magnetic resonance compatibility is achieved.
Drawings
Fig. 1 shows a schematic structural diagram of a fiber optic temperature sensor integrated radio frequency ablation electrode according to an embodiment of the present application.
Fig. 2 shows a schematic structural diagram of a fiber optic temperature sensor integrated radio frequency ablation electrode according to another embodiment of the present application.
Fig. 3 is a schematic view showing the structure of a conventional electrode with a tungsten rod built therein.
Description of the reference numerals
1, an optical fiber temperature sensor probe; 2, an optical fiber; 31 a first ablation recording common electrode; 32 a second ablation recording common electrode; 33 a third erasing recording common electrode; 34 a fourth ablation recording common electrode; 35 a fifth ablation recording common electrode; 4 a recording electrode; 5, an optical fiber joint; 6 connecting a plug; 7, sleeving a sleeve; 8, a tungsten rod; 9 conducting wires.
Detailed Description
Exemplary embodiments of the present application are described below with reference to the accompanying drawings. It should be understood that the detailed description is only intended to teach one skilled in the art how to practice the present application, and is not intended to be exhaustive or to limit the scope of the application.
The application provides a radio frequency ablation electrode integrated with a fiber temperature sensor. As shown in figure 1, the radio frequency ablation electrode integrated with the optical fiber temperature sensor comprises an optical fiber temperature sensor probe 1, an optical fiber 2, a first ablation recording common electrode 31, a second ablation recording common electrode 32, an optical fiber connector 5, a connecting plug 6, a sleeve 7 and a lead 9.
The first ablation recording common electrode 31 and the second ablation recording common electrode 32 can realize ablation and recording functions by using a macro electrode of the prior art. The first ablation recording common electrode 31 and the second ablation recording common electrode 32 can be connected with an external radiofrequency ablation device through the lead 9 and the connecting plug 6 to realize a radiofrequency ablation function, or connected with an external electroencephalogram recording device to realize a recording function. The wire 9 may be an enameled wire having a diameter of 50 μm. The first ablation-recording common electrode 31 and the second ablation-recording common electrode 32 are disposed at the end of the sleeve 7 at intervals in the axial direction of the sleeve 7.
By forming radio frequency current between the first ablation recording common electrode 31 and the second ablation recording common electrode 32, the radio frequency ablation of the human tissue around the center of the circle is realized by taking the central positions of the first ablation recording common electrode 31 and the second ablation recording common electrode 32 as the center of the circle.
The optical fiber temperature sensor mentioned in the present application is based on the optical fiber temperature measurement technology mature in the industry, and the basic principle is that a small block of special fluorescent material is placed at the end of the optical fiber 2 to form the optical fiber temperature sensor probe 1. The optical fiber connector 5 is connected to the laser generator and the signal demodulator. The laser generator generates a laser pulse which is transmitted through the optical fiber 2 and irradiates the phosphor. After the fluorescent substance is irradiated, fluorescence is generated, and the fluorescence signal is transmitted back to the signal demodulator through the optical fiber 2. The characteristics such as spectrum/phase of the fluorescence generated after the fluorescent substance is irradiated are related to the temperature, and the signal demodulator can calculate the temperature around the fluorescent substance by analyzing the characteristics of the received fluorescence.
As shown in fig. 1, the optical fiber temperature sensor probe 1 may be located at a position intermediate the first ablation-recording common electrode 31 and the second ablation-recording common electrode 32, and the optical fiber temperature sensor probe 1 may be located at a side wall or inside of the sheath 7, preferably disposed on the axis of the sheath 7.
It can be understood that the implementation of the fiber optic temperature sensor probe 1 disposed at the casing axis may be less technically difficult to implement. The functional relationship between the surface temperatures of the fiber temperature sensor probe 1 and the first ablation recording common electrode 31 and the second ablation recording common electrode 32 can be calculated through thermodynamic modeling, experiments and the like. Thus, by measuring the temperature of the optical fiber temperature sensor probe 1 in the sleeve, the temperature of the surface of the ablation recording common electrode and the nearby human tissue can be calculated. The device is shut down to protect the patient after ablation records that the common electrode surface and nearby body tissue are above a set value, such as by existing control systems.
The application applies the optical fiber temperature measurement technology to the radio frequency ablation electrode, satisfies the temperature measurement, and simultaneously takes the optical fiber as the transmission carrier of the temperature signal, avoids the interference of electromagnetic environments such as magnetic resonance and the like, has magnetic resonance compatibility, and can realize the radio frequency ablation of the magnetic resonance real-time navigation. The use of fiber optic temperature sensors in radiofrequency ablation electrodes is not readily envisioned by those skilled in the art.
In one embodiment of the present application, as shown in fig. 1, the fiber optic temperature sensor integrated radiofrequency ablation electrode further comprises a plurality of recording electrodes 4. The recording electrode 4 may be realized as a macro-electrode, and the recording electrode 4 may also be realized as a micro-electrode. The first ablation recording common electrode 31, the second ablation recording common electrode 32 and the recording electrode 4 are provided on the side wall of the sleeve 7 at intervals in the axial direction of the sleeve 7. The recording electrodes 4 are used for detecting electric signals at different positions of human tissues.
In another embodiment of the present application, as shown in fig. 2, the ablation recording common electrode may further include a third ablation recording common electrode 33, a fourth ablation recording common electrode 34, and a fifth ablation recording common electrode 35 implemented with macro electrodes.
The first ablation-recording common electrode 31, the second ablation-recording common electrode 32, the third ablation-recording common electrode 33, the fourth ablation-recording common electrode 34, and the fifth ablation-recording common electrode 35 are provided on the sidewall of the sleeve 7 at intervals in the axial direction of the sleeve 7.
The interval distances between the ablation recording common electrodes arranged at intervals can be equal, and the plurality of optical fiber temperature sensor probes are respectively positioned at the central positions between the adjacent ablation recording common electrodes. When the electrodes are arranged at equal intervals, the electrode contact points can be simply and clearly used as a ruler for doctors, and the implantation depth of the electrodes can be judged under the condition of not needing complex calculation or table lookup, which has important significance in clinical operation. Meanwhile, in a magnetic resonance image, the electrode contacts arranged at equal intervals can also be used as a scale, so that a doctor can relatively conveniently judge the positions and the like of the electrodes in the image.
The radio frequency ablation electrode integrated with the optical fiber temperature sensor further comprises a plurality of optical fiber temperature sensor probes 1, wherein the plurality of optical fiber temperature sensor probes 1 are respectively arranged between the second ablation recording common electrode 32 and the third ablation recording common electrode 33, between the third ablation recording common electrode 33 and the fourth ablation recording common electrode 34, and between the fourth ablation recording common electrode 34 and the fifth ablation recording common electrode 35.
It is to be understood that the above embodiments are merely exemplary and the number of the ablation recording common electrodes is not limited. The number of the ablation recording common electrode and the optical fiber temperature sensor probe 1 can be expanded, and the measurement range is expanded. That is, the sleeve 7 has a plurality of electrodes that can be used for ablation, and the doctor can optionally select each contact position as a radio frequency ablation electrode pair, thereby enlarging the range of radio frequency ablation of the electrodes.
In addition, the linear characteristic of the temperature field is utilized by using the optical fiber temperature sensor probe arranged inside the electrode (for example, on the axis), and the temperature value in the human tissue outside the radio frequency ablation electrode is calculated through the temperature value at the position of the optical fiber temperature sensor probe. The calculation has certain errors, and if a plurality of optical fiber temperature sensor probes are arranged at different positions and the temperatures of different positions in a temperature field are measured in real time, the error of calculating the temperature in the human tissue can be greatly reduced.
As shown in fig. 3, in a conventional electrode, a tungsten rod 8 is usually built in a sleeve 7 at the front end of the electrode to enhance the rigidity of the front end of the electrode, so as to ensure that the electrode is always kept straight during the operation. The diameter of this tungsten rod 8 is usually between 0.4 and 0.6 mm.
The radio frequency ablation electrode integrated with the optical fiber temperature sensor can remove the tungsten rod 8, and the optical fiber 2 is arranged at the position of the tungsten rod 8. The optical fiber 2 can be sleeved with an insulating protection tube with certain hardness, so that the optical fiber temperature sensor is protected in an insulating manner, and the rigidity of the front end (left side in the figure) of the radio frequency ablation electrode integrated with the optical fiber temperature sensor is ensured. The outer diameter of the protective tube may be 0.6mm and the inner diameter may be 0.3mm. The material of the protection tube may be a polymer material, for example: polyvinyl chloride (PVC), polyester resin (PET), ABS plastic, polyimide (PI), thermoplastic polyurethane rubber (TPU), polytetrafluoroethylene (PTFE), nylon, and the like.
The electroencephalogram temperature measurement system can be integrated on an electroencephalogram electrode, can be used for supporting radiofrequency ablation, can also be used for accurately measuring temperature data of intracranial specific positions when acquiring electroencephalogram signals, and is used for supporting related scientific research.
The magnetic resonance imaging device can be integrated on radio frequency ablation electrodes for other body parts to realize magnetic resonance compatibility; such as abdominal ablation electrodes, cardiopulmonary ablation electrodes, and the like.
Especially when the optical fiber temperature sensor probe is arranged on the side wall of the sleeve, the optical fiber temperature sensor probe can also be used as an energy projector for carrying out nerve regulation treatment based on laser irradiation.
While the foregoing is directed to the preferred embodiment of the present application, it will be understood by those skilled in the art that various changes and modifications may be made without departing from the spirit and scope of the application.

Claims (2)

1. A radio frequency ablation electrode integrated with a fiber temperature sensor is characterized in that,
the radio frequency ablation electrode integrated with the optical fiber temperature sensor comprises a sleeve (7) and the optical fiber temperature sensor,
a plurality of ablation recording common electrodes are integrated on the sleeve (7), the plurality of ablation recording common electrodes comprise a first ablation recording common electrode (31) and a second ablation recording common electrode (32),
the optical fiber temperature sensor comprises an optical fiber temperature sensor probe (1);
the optical fiber temperature sensor probe (1) is positioned in the middle of the first ablation recording common electrode (31) and the second ablation recording common electrode (32), and the optical fiber temperature sensor probe (1) is positioned on the side wall of the sleeve (7);
the plurality of ablation recording common electrodes are arranged on the side wall of the sleeve (7) at intervals along the axial direction of the sleeve (7),
two adjacent ablation recording common electrodes in the plurality of ablation recording common electrodes form an ablation electrode pair,
the radiofrequency ablation electrode integrated with the optical fiber temperature sensor comprises a plurality of ablation electrode pairs and a plurality of optical fiber temperature sensor probes (1),
the plurality of optical fiber temperature sensor probes (1) are respectively arranged in the middle position between two ablation recording common electrodes of the plurality of ablation electrode pairs;
the interval distances among the ablation recording common electrodes which are arranged at intervals are equal, and the plurality of optical fiber temperature sensor probes (1) are respectively arranged at the central positions of the ablation electrode pairs;
the optical fiber of the optical fiber temperature sensor is arranged in a sleeve at the front end of the electrode, an insulating and hard protection tube is sleeved outside the optical fiber, the protection tube is made of high polymer materials, and the high polymer materials comprise polyvinyl chloride, polyester resin, plastic, polyimide, thermoplastic polyurethane rubber, polytetrafluoroethylene and nylon;
the optical fiber joint of the optical fiber temperature sensor is connected to the laser generator and the signal demodulator, and the probe of the optical fiber temperature sensor is used as an energy projector for laser irradiation;
wherein the radio frequency ablation electrode integrated with the optical fiber temperature sensor also comprises an optical fiber (2) and an optical fiber joint (5),
the optical fiber temperature sensor probe (1) is integrated at the end part of the optical fiber (2), and the optical fiber temperature sensor probe (1) realizes signal exchange with external equipment through the optical fiber (2) and the optical fiber joint (5);
wherein the radio frequency ablation electrode integrated with the optical fiber temperature sensor further comprises one or more recording electrodes (4), and the first ablation recording common electrode (31), the second ablation recording common electrode (32) and the one or more recording electrodes (4) are arranged on the side wall of the sleeve (7) at equal intervals along the axial direction of the sleeve (7);
wherein the radio frequency ablation electrode integrated with the optical fiber temperature sensor comprises a lead (9), the lead (9) is used for connecting the first ablation recording common electrode (31) and the second ablation recording common electrode (32) to an external radio frequency ablation device, and radio frequency ablation is realized by forming radio frequency current between the first ablation recording common electrode (31) and the second ablation recording common electrode (32).
2. The RF ablation electrode integrated with a fiber optic temperature sensor according to claim 1,
the first ablation recording common electrode (31) and the second ablation recording common electrode (32) are arranged at the end of the sleeve (7) at intervals along the axial direction of the sleeve (7).
CN202110378981.3A 2021-04-08 2021-04-08 Radio frequency ablation electrode integrated with optical fiber temperature sensor Active CN113100922B (en)

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CN202110378981.3A CN113100922B (en) 2021-04-08 2021-04-08 Radio frequency ablation electrode integrated with optical fiber temperature sensor

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CN202110378981.3A CN113100922B (en) 2021-04-08 2021-04-08 Radio frequency ablation electrode integrated with optical fiber temperature sensor

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CN113100922B true CN113100922B (en) 2023-02-21

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020123696A1 (en) * 2001-03-01 2002-09-05 Kokate Jaydeep Y. Catheters with fluorescent temperature sensors
US7285118B1 (en) * 2002-07-18 2007-10-23 Functional Neuroscience Inc. Brain stimulation lead used for lesioning

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020123696A1 (en) * 2001-03-01 2002-09-05 Kokate Jaydeep Y. Catheters with fluorescent temperature sensors
US7285118B1 (en) * 2002-07-18 2007-10-23 Functional Neuroscience Inc. Brain stimulation lead used for lesioning

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