CN113088437B

CN113088437B - Mycoplasma analyzer

Info

Publication number: CN113088437B
Application number: CN202110315367.2A
Authority: CN
Inventors: 林华青; 王万春; 苏建华
Original assignee: Zhuhai Deer Bioengineering Co ltd
Current assignee: Zhuhai Deer Bioengineering Co ltd
Priority date: 2021-03-24
Filing date: 2021-03-24
Publication date: 2024-01-05
Anticipated expiration: 2041-03-24
Also published as: CN113088437A

Abstract

The utility model discloses a mycoplasma analyzer, which comprises a machine table, an incubator, a culture box making device, a culture box transferring mechanism and a camera device, wherein a first sliding rail is arranged on the machine table along the front-back direction, a slidable carrier plate is arranged on the first sliding rail, a culture box limiting groove is arranged on the carrier plate, and the front end of the first sliding rail is a culture box feeding station; the culture box making device is used for making the culture box and placing the completed culture box in the culture box limiting groove; the incubator is provided with a chamber and a chamber door capable of sealing the chamber; the culture box transferring mechanism is provided with a supporting plate, and the supporting plate can support the culture box on the culture box feeding station and transfer the culture box into the cavity; the camera device is connected with the culture box transferring mechanism and faces the supporting plate to shoot the mixture in the culture box. The culture box making device places the culture box which is manufactured in the culture box limiting groove to cultivate the sample, and the camera shooting device shoots the state of the mixture in the culture box, so that the method is convenient and quick.

Description

Mycoplasma analyzer

Technical Field

The utility model relates to the technical field of medical equipment, in particular to a mycoplasma analyzer.

Background

Microorganisms include the following eight general classes: bacteria, viruses, fungi, actinomycetes, rickettsia, mycoplasma, chlamydia, and spirochetes. The microorganism is tiny and closely related to human beings, and covers a plurality of beneficial and harmful species, and the microorganism is widely applied to various fields of food, medicine, industry and agriculture, environmental protection, sports and the like. The drug sensitivity test refers to a test for determining the bacteriostatic or bactericidal ability of a drug in vitro. Mixing a microorganism sample and a culture medium to prepare a sample liquid, wherein the sample can be body fluid, microorganisms such as mycoplasma or bacteria are contained in the sample, then injecting the sample liquid into a culture box with corresponding staining liquid, then placing the culture box in an environment with proper temperature to cultivate the mixture of the sample liquid and the staining liquid, and finally judging the drug sensitivity by observing the color of the mixture in the culture box. The device at the present stage is simpler, the cultivation effect of the incubator is poorer, the incubator is required to be manually operated one by one, and the overall efficiency of mycoplasma cultivation and inspection analysis is low.

Disclosure of Invention

The present utility model aims to solve at least one of the technical problems existing in the prior art. Therefore, the mycoplasma analyzer provided by the utility model can replace manual mycoplasma cultivation and detection analysis, and has high efficiency.

The mycoplasma analyzer comprises a machine table, an incubator, a culture box making device, a culture box transferring mechanism and a camera device, wherein a first sliding rail is arranged on the machine table along the front-back direction, a slidable carrier plate is arranged on the first sliding rail, a culture box limiting groove is arranged on the carrier plate, and the front end of the first sliding rail is a culture box feeding station; the culture box making device is used for making a culture box and placing the culture box in the culture box limiting groove; the incubator is arranged on the machine table and is provided with a chamber and a box door capable of sealing the chamber; the culture box transferring mechanism is arranged on the machine table, a supporting plate is arranged on the culture box transferring mechanism, and the supporting plate can support the culture box on the culture box feeding station and transfer the culture box into the cavity; the camera device is connected with the culture box transferring mechanism and faces the supporting plate to shoot the mixture in the culture box.

The mycoplasma analyzer provided by the embodiment of the utility model has at least the following beneficial effects: initially, a carrier plate approaches to a culture box making device, the culture box making device places the manufactured culture box in a culture box limiting groove, and then the carrier plate conveys the culture box to a culture box feeding station; at the moment, the box door is in an open state, the supporting plate supports the culture box on the culture box feeding station and penetrates through the box door, and then the supporting plate places the culture box in the cavity; after microorganisms such as mycoplasma are propagated in the cavity for a certain time, the cavity door is opened, the supporting plate supports the culture box in the culture box fixing groove, at the moment, the camera device is opposite to the culture box, and the camera device can shoot the state of the mixture in the culture box so as to recognize the color and other changes of the mixture, analyze the growth condition or the drug sensitivity condition of the mycoplasma, and the like, and is convenient and rapid, and no manual operation is needed.

According to some embodiments of the utility model, the incubator is provided with a heating mechanism and a vertically rotatable rotating bracket in the chamber, a plurality of layers of support plates are arranged on the rotating bracket at intervals up and down, a plurality of culture box fixing grooves are arranged on the support plates, and the support plates can support the culture boxes and transfer the culture boxes to the culture box fixing grooves.

According to some embodiments of the utility model, the box door is arranged on the front side of the incubator, the box door is arranged above the incubator feeding station, the incubator transferring mechanism comprises a first lifting moving mechanism connected with the machine table, a first mounting plate arranged on the output end of the first lifting moving mechanism, a first front-back moving mechanism arranged on the first mounting plate, the supporting plate is connected with the first mounting plate, a limiting plate is arranged on the output end of the first front-back moving mechanism, the limiting plate is arranged above the supporting plate, a containing cavity for containing the incubator can be formed between the limiting plate and the supporting plate, and the opening of the containing cavity faces to the left side.

According to some embodiments of the utility model, the culture box transferring mechanism further comprises a first left-right moving mechanism arranged on the first mounting plate, wherein a first baffle plate is connected to the output end of the first left-right moving mechanism, the first baffle plate faces the opening of the accommodating cavity, and the first baffle plate can be abutted against the left side surface of the culture box.

According to some embodiments of the utility model, the machine is provided with a second left-right moving mechanism at the left side of the culture box feeding station, and the output end of the second left-right moving mechanism is provided with a first pushing plate, and the first pushing plate can push the culture box on the culture box feeding station into the accommodating cavity.

According to some embodiments of the utility model, the supporting plate is made of transparent material, the image pickup device is connected with the first mounting plate through a connecting plate, and the image pickup device is located below the supporting plate.

According to some embodiments of the utility model, a supporting table is arranged on the machine table, the supporting table is positioned above the side of the feeding station of the culture box, the incubator is arranged on the supporting table, a first rotary driving mechanism is arranged on the supporting table, and the output end of the first rotary driving mechanism extends into the incubator and is connected with the rotary bracket.

According to some embodiments of the utility model, the rotary support comprises a hollow shell, the peripheral wall of the shell is provided with ventilation holes, and the heating mechanism is arranged in the shell.

According to some embodiments of the utility model, the machine is provided with a culture box material rack, a culture bottle material tray and a suction head material tray on the periphery of the first sliding rail, the carrier plate is also provided with a culture bottle limit hole, the culture box making device comprises a box carrying mechanism, a bottle carrying mechanism, a box cover clamping jaw and a liquid injection mechanism which are all arranged on the machine, the box carrying mechanism can carry a culture box on the culture box material rack into the culture box limit groove, the bottle carrying mechanism is movably arranged above the first sliding rail and the culture bottle material tray, the bottle carrying mechanism can clamp a bottle cover of a culture bottle and carry the culture bottle from the culture bottle material tray into the culture bottle limit hole, the box cover clamping jaw is movably arranged above the first sliding rail, the box cover can clamp and lift a box cover of the culture box, the liquid injection mechanism can be arranged above the space between the first sliding rail and the suction head material tray, and the liquid injection mechanism can carry the suction head of the culture bottle and inject sample liquid into the suction head material tray through the suction head clamping jaw.

According to some embodiments of the utility model, the culture box making device further comprises a second lifting moving mechanism arranged on the machine platform, a third front-back moving mechanism, a third left-right moving mechanism and a mounting frame which are all arranged on the second lifting moving mechanism, wherein the second lifting moving mechanism, the third front-back moving mechanism and the third left-right moving mechanism can respectively drive the mounting frame to move along the up-down, front-back and left-right directions, and the bottle carrying mechanism, the box cover clamping jaw and the liquid filling mechanism are all connected with the mounting frame.

Additional aspects and advantages of the utility model will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the utility model.

Drawings

The foregoing and/or additional aspects and advantages of the utility model will become apparent and may be better understood from the following description of embodiments taken in conjunction with the accompanying drawings in which:

FIG. 1 is a schematic diagram of a Mycoplasma analyzer according to an embodiment of the present utility model;

FIG. 2 is a schematic view showing the structure of a machine and a transfer mechanism of a culture cassette in the mycoplasma analyzer shown in FIG. 1;

FIG. 3 is an enlarged partial schematic view of FIG. 2A;

FIG. 4 is a schematic view showing the structures of a rotary support, a support plate, a heating mechanism and a rotary driving mechanism in a mycoplasma analyzer according to an embodiment of the present utility model;

FIG. 5 is a schematic longitudinal cross-sectional view of the structure of FIG. 4;

FIG. 6 is a schematic view showing the structure of a culture cassette making device in a mycoplasma analyzer according to an embodiment of the present utility model;

FIG. 7 is a schematic view of a mechanism of a first slide rail, a second back and forth movement mechanism and a body jaw in a mycoplasma analyzer according to an embodiment of the present utility model;

FIG. 8 is a schematic diagram of the bottle handling mechanism, the cap clamping jaw and the liquid injection mechanism of the mycoplasma analyzer according to the embodiment of the utility model;

FIG. 9 is a schematic diagram showing a mechanism of a flask tray and cassette handling mechanism in a mycoplasma analyzer according to an embodiment of the present utility model;

FIG. 10 is a schematic diagram showing a cross-sectional view of a flask tray and cassette handling mechanism in a mycoplasma analyzer according to an embodiment of the utility model.

Reference numerals:

machine 100, first slide rail 110, culture box feeding station 111, second left-right movement mechanism 120, push plate 121, support 130, first rotation driving mechanism 131, culture box rack 140, bottom plate structure 141, enclosure 142, opening 143, notch 144, culture bottle tray 150, suction head tray 160, second front-back movement mechanism 170, fifth left-right movement mechanism 180, body gripping jaw 181, incubator 200, door 210, heating mechanism 220, electric bar 221, heat sink 222, rotation bracket 230, housing 231, ventilation hole 232, culture box making device 300, box transporting mechanism 310, guide rail 311, sixth left-right movement mechanism 312, second push plate 313, bottle transporting mechanism 320, bottle gripping jaw 321, and third left-right movement mechanism second rotary drive mechanism 322, lid jaw 330, liquid injection mechanism 340, third elevating movement mechanism 341, second mounting plate 342, fourth elevating movement mechanism 343, cylinder 344, second shutter 345, second elevating movement mechanism 350, third forward and backward movement mechanism 360, third leftward and rightward movement mechanism 370, mounting frame 380, support plate 400, culture cassette fixing groove 410, avoidance hole 411, support plate 500, culture cassette limiting groove 510, culture bottle limiting hole 520, culture cassette transfer mechanism 600, support plate 610, first elevating movement mechanism 620, first mounting plate 630, first forward and backward movement mechanism 640, limiting plate 650, first leftward and rightward movement mechanism 660, first shutter 670, connecting plate 680, imaging device 700.

Detailed Description

Embodiments of the present utility model are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative only and are not to be construed as limiting the utility model.

In the description of the present utility model, it should be understood that the direction or positional relationship indicated in reference to the description of the orientation, such as upper, lower, front, rear, left, right, etc., may be based on the direction or positional relationship shown in the drawings, merely for convenience of describing the present utility model and simplifying the description, and does not indicate or imply that the apparatus or element to be referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present utility model.

In the description of the present utility model, a plurality means one or more, and a plurality means two or more, and it is understood that greater than, less than, exceeding, etc. does not include the present number, and it is understood that greater than, less than, within, etc. include the present number. The description of the first and second is for the purpose of distinguishing between technical features only and should not be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.

In the description of the present utility model, unless explicitly defined otherwise, terms such as arrangement, installation, connection, etc. should be construed broadly and the specific meaning of the terms in the present utility model can be reasonably determined by a person skilled in the art in combination with the specific contents of the technical scheme.

Referring to fig. 1 to 4, the utility model discloses a mycoplasma analyzer, comprising a machine 100, an incubator 200, a incubator making device 300, an incubator transferring mechanism 600 and a camera 700, wherein a first sliding rail 110 is arranged on the machine 100 along the front-back direction, a slidable carrier plate 500 is arranged on the first sliding rail 110, an incubator limiting groove 510 is arranged on the carrier plate 500, and the front end of the first sliding rail 110 is provided with an incubator feeding station 111; the culture box making device 300 is arranged on the machine 100 in a region close to the first sliding rail 110, and the culture box making device 300 is used for making a culture box and placing the completed culture box in the culture box limiting groove 510; the incubator 200 is arranged on the machine 100, and the incubator 200 is provided with a chamber and a chamber door 210 capable of sealing the chamber; the culture box transferring mechanism 600 is arranged on the machine 100, a supporting plate 610 is arranged on the culture box transferring mechanism 600, and the supporting plate 610 can support the culture box on the culture box feeding station 111 and transfer the culture box into the cavity; the camera 700 is connected to the cassette transfer mechanism 600 and faces the tray 610 to take a picture of the mixture in the cassette.

Initially, the carrier plate 500 approaches the culture box making device 300, the culture box making device 300 places the manufactured culture box in the culture box limiting groove 510, and then the carrier plate 500 conveys the culture box to the culture box feeding station 111; at this time, the door 210 is opened, the tray 610 lifts up the cassette on the cassette loading station 111 and passes through the door 210, and then the tray 610 places the cassette in the chamber; after microorganisms such as mycoplasma are propagated in the chamber for a certain time, the chamber door 210 is opened, the supporting plate supports the culture box in the culture box fixing groove 410, at the moment, the camera device 700 is opposite to the culture box, and the camera device 700 can shoot the state of the mixture in the culture box so as to identify the color and other changes of the mixture, analyze the growth condition or drug sensitivity condition of the mycoplasma, and the like, and is convenient and rapid, and no manual operation is needed.

In some embodiments of the present utility model, incubator 200 has a warming mechanism 220 and a vertically rotatable rotating support 230 within the chamber, the rotating support 230 has a plurality of support plates 400 spaced up and down, the support plates 400 have a plurality of cassette fixing slots 410, and the support plates 610 can hold up the cassettes and transfer the cassettes to the cassette fixing slots 410. The heating mechanism 220 can heat the air in the chamber, so that an environment suitable for cultivating microorganisms such as mycoplasma is formed in the chamber, and the growth of the microorganisms such as mycoplasma is accelerated. The culture cassette fixing groove 410 is used for limiting the culture cassette, and preventing the culture cassette from falling from the support plate 400; the rotating bracket 230 can rotate with the support plate 400 and the culture box fixing grooves 410, so that each culture box fixing groove 410 can be opposite to the box opening of the incubator 200, each culture box fixing groove 410 can limit one culture box, the number of culture boxes which can be cultivated in one time of the incubator 200 is large, and the efficiency of cultivating microorganisms such as mycoplasma is improved.

In some embodiments of the present utility model, the box door 210 is disposed on the front side of the incubator 200, the box door 210 is disposed above the incubator loading station 111, the incubator transferring mechanism 600 includes a first lifting moving mechanism 620 connected to the machine 100, a first mounting plate 630 on an output end of the first lifting moving mechanism 620, a first front-back moving mechanism 640 disposed on the first mounting plate 630, the pallet 610 is connected to the first mounting plate 630, a limiting plate 650 is disposed on an output end of the first front-back moving mechanism 640, the limiting plate 650 is disposed above the pallet 610, a receiving cavity for receiving the incubator can be formed between the limiting plate 650 and the pallet 610, and an opening of the receiving cavity faces to the left.

When a containing cavity for containing the culture box is formed between the limiting plate 650 and the supporting plate 610, the culture box can enter the containing cavity through the opening of the containing cavity, the culture box is supported by the supporting plate 610, the limiting plate 650 limits the culture box on the supporting plate 610, and the culture box is prevented from sliding along the front-back direction; then the first lifting and moving mechanism 620 drives the supporting plate 610 to lift and the supporting plate 610 faces the box opening, the first front and back moving mechanism 640 drives the limiting plate 650 to move backwards and extend into the chamber, and the culture box is pushed into the chamber by the limiting plate 650 and falls into the culture box fixing groove 410, so that the transfer of the culture box to the culture box fixing groove 410 is completed.

Since the opening of the accommodating chamber is directed to the left, the cartridge loading station 111 is positioned at the left of the supporting plate 610 and the limiting plate 650, so that the cartridge can be smoothly introduced into the accommodating chamber. The first elevating and moving mechanism 620 is connected to the left or right machine 100 area of the cassette loading station 111.

In some embodiments of the present utility model, the culture cassette transferring mechanism 600 further comprises a first left-right moving mechanism 660 provided on the first mounting plate 630, wherein a first baffle 670 is connected to an output end of the first left-right moving mechanism 660, the first baffle 670 faces an opening of the accommodating cavity, and the first baffle 670 can abut against a left side surface of the culture cassette. The first left-right moving mechanism 660 may drive the first shutter 670 to move away from or extend into the accommodating chamber, and when the first shutter 670 extends into the accommodating chamber, the inner wall of the first shutter 670 may abut against the left side surface of the culture cassette, and the first shutter 670 may prevent the culture cassette from slipping off the tray 610 from the opening of the accommodating chamber. It will be appreciated that the first shutter 670 is U-shaped, the opening of the first shutter 670U-shaped groove faces the opening of the accommodating chamber, and when the first shutter 670 extends into the accommodating chamber, the inner wall of the first shutter 670U-shaped groove abuts against the front and rear and left sides of the culture cassette.

In some embodiments of the present utility model, the machine 100 is provided with a second left-right moving mechanism 120 at the left side of the incubator feeding station 111, and a first push plate 121 is provided at the output end of the second left-right moving mechanism 120, where the first push plate 121 can push the incubator on the incubator feeding station 111 into the accommodating chamber. The second left-right moving mechanism 120 drives the first push plate 121 to move in the left-right direction, and when the first push plate 121 moves from left to right, the first push plate 121 can push the culture cassette on the culture cassette loading station 111 into the accommodating chamber.

In some embodiments of the present utility model, the supporting plate 610 is made of transparent material, the image capturing device 700 is connected to the first mounting plate 630 through the connecting plate 680, and the image capturing device 700 is located below the supporting plate 610. Because the camera device 700 is located below the supporting plate 610 and the supporting plate 610 is transparent, when the supporting plate 610 supports the culture box, the camera device 700 can shoot the mixture in the culture box, and the efficiency is high.

In some embodiments of the present utility model, a support stand 130 is provided on the machine 100, the support stand 130 is located above the side of the feeding station 111 of the incubator 200, the support stand 130 is provided with a first rotation driving mechanism 131, and an output end of the first rotation driving mechanism 131 extends into the incubator 200 and is connected to a rotation bracket 230. The support table 130 functions to support the incubator 200 and the first rotation driving mechanism 131; the first rotary driving mechanism 131 drives the rotary support 230 to rotate so that different cartridge fixing grooves 410 can face the mouth of the incubator 200.

Referring to fig. 5, the rotating bracket 230 includes a hollow housing 231, and a ventilation hole 232 is provided in a peripheral wall of the housing 231, and the heating mechanism 220 is provided in the housing 231. The housing 231 serves to protect the warming mechanism 220 and to prevent the warming mechanism 220 from contacting other components, thereby preventing the warming mechanism 220 from damaging other components and also preventing personnel from touching the warming mechanism 220 by mistake. The ventilation holes 232 allow air inside and outside the housing 231 to circulate, and the air heated by the heating mechanism 220 communicates with air outside the housing 231 through the ventilation holes 232, so that the temperature inside the chamber is appropriate.

In some embodiments of the present utility model, the heating mechanism 220 includes an electric heating rod 221 disposed in the housing 231 and a heat sink 520 wound around the electric heating rod 221. The electric heating rod 221 is a common heating element, the using method is simple and convenient to control, and the cooling fins 520 help to quickly transfer the heat generated by the electric heating rod 221 into the air.

In some embodiments of the present utility model, the support plate 400 is disc-shaped, the bottom wall of the culture box fixing slot 410 is provided with a avoiding hole 411, the avoiding hole 411 can allow the supporting plate 610 to extend in, and the openings of the culture box fixing slot 410 and the avoiding hole 411 are both arranged on the outer circumferential wall of the support plate 400. Because the openings of the culture box fixing groove 410 and the avoidance hole 411 are all arranged on the outer circumferential wall of the support plate 400, the support plate 610 and the culture box can respectively extend into the avoidance hole 411 and the culture box fixing groove 410, so that the culture box can accurately fall into the culture box fixing groove 410, and other areas of the bottom wall of the culture box fixing groove 410 play a role in supporting the culture box.

The machine 100 is further provided with a waste collection tank, and the cultivation box after cultivation and detection can be thrown into the waste collection tank through the cultivation box transferring mechanism 600. The box door 210 is disposed on the supporting table 130, the box door 210 adopts a pushing door structure, the supporting table 130 is provided with a fourth left-right moving mechanism, an output end of the fourth left-right moving mechanism is connected with the box door 210, and the fourth left-right moving mechanism drives the box door 210 to move along a left-right direction so as to open or close the incubator 200.

The first elevating and moving mechanism 620 is a screw moving pair, and redundant description is not made here. The first back-and-forth movement mechanism 640 includes a first motor provided on the first mounting plate 630, a first driving wheel provided on an output end of the first motor, a first driven wheel provided on the first mounting plate 630, and a first belt wound around the first driving wheel and the first driven wheel, the first driving wheel and the first driven wheel being provided along a front-back direction, and the limiting plate 650 being connected with the first belt. The first motor drives the first belt to rotate, so that the limiting plate 650 can be driven to move in the front-rear direction. The second forward-backward movement mechanism 130, the second left-right movement mechanism 120, and the first left-right movement mechanism 660 are similar and identical in structure and principle to the first forward-backward movement mechanism 640, and redundant description thereof is not made here.

It will be appreciated that the first rotary driving mechanism 131 may include a second motor disposed on the supporting table 130, a second driving wheel disposed on an output end of the second motor, a transmission shaft rotatably penetrating through the supporting table 130, a second driven wheel disposed on a lower end of the transmission shaft, and a second belt wound around the second driving wheel and the second driven wheel, and an upper end of the transmission shaft extends into the incubator 200 and is connected with the rotary bracket 230.

Referring to fig. 6 to 8, the machine 100 is provided with a culture box rack 140, a culture bottle tray 150 and a suction head tray 160 on the periphery of the first slide rail 110, a culture bottle limiting hole 520 is further provided on the carrier plate 500, the culture box making device 300 comprises a box carrying mechanism 310, a bottle carrying mechanism 320, a box cover clamping jaw 330 and a liquid filling mechanism 340 which are all arranged on the machine 100, the box carrying mechanism 310 can carry the culture box on the culture box rack 140 into the culture box limiting groove 510, the bottle carrying mechanism 320 is movably arranged above the first slide rail 110 and the culture bottle tray 150, the bottle carrying mechanism 320 can clamp the bottle cover of the culture bottle and carry the culture bottle from the culture bottle tray 150 into the culture bottle limiting hole 520, the box cover clamping jaw 330 is movably arranged above the first slide rail 110, the box cover clamping jaw 330 can clamp and lift the box cover of the culture box, and the liquid filling mechanism 340 is arranged above the first slide rail 110 and the suction head tray 160, and the liquid filling mechanism 340 can carry the suction head on the suction head 160 and fill the sample liquid in the culture box.

When the position of the carrier 500 corresponds to the position of the culture box material rack 140, the box conveying mechanism 310 can convey the culture boxes on the culture box material rack 140 into the culture box limiting groove 510 one by one; when the position of the carrier plate 500 corresponds to the position of the cover clamping jaw 330, the cover clamping jaw 330 clamps and lifts the cover of the culture box; when the position of the carrier plate 500 corresponds to the position of the culture bottle tray 150, the bottle carrying mechanism 320 clamps the bottle cap of the culture bottle and carries the culture bottle from the culture bottle tray 150 into the culture bottle limiting hole 520; when the position of the carrier plate 500 corresponds to the position of the tip tray 160, the filling mechanism 340 carries the tip removed from the tip tray 160 and fills the sample liquid in the flask into the culture cassette through the tip. The sample liquid is injected into the culture box without manual operation; after the production of one culture box is completed, the next culture box can be produced, and the method is convenient and quick; and each sample liquid can be injected into different culture boxes by different suction heads, so that cross contamination of the sample liquid is avoided.

A plurality of culture cassettes can be accommodated on the culture cassette material frame 140, a plurality of culture flasks can be accommodated on the culture flask material tray 150, and a plurality of suction heads can be accommodated on the suction head material tray 160, so that the culture cassette making device 300 can continuously make a plurality of culture cassettes with mixtures. The machine 100 is further provided with a second front-back moving mechanism 170 on the periphery of the first sliding rail 110, an output end of the second front-back moving mechanism 170 is connected with the carrier plate 500, the second front-back moving mechanism 170 can drive the carrier plate 500 to move on the first sliding rail 110 along the front-back direction, that is, the second front-back moving mechanism 170 is used for conveying the carrier plate 500 near the incubator box manufacturing device 300 to the incubator feeding station 111 at first.

In some embodiments of the present utility model, the incubator box manufacturing apparatus 300 further includes a second lifting moving mechanism 350 disposed on the machine 100, and a third front-back moving mechanism 360, a third left-right moving mechanism 370 and a mounting frame 380 all disposed on the second lifting moving mechanism 350, where the second lifting moving mechanism 350, the third front-back moving mechanism 360 and the third left-right moving mechanism 370 can respectively drive the mounting frame 380 to move in the up-down, front-back and left-right directions, and the bottle transporting mechanism 320, the box cover clamping jaw 330 and the liquid filling mechanism 340 are all connected with the mounting frame 380.

The second lifting and moving mechanism 350, the third front-back moving mechanism 360 and the third left-right moving mechanism 370 can drive the mounting frame 380 to move along the front-back, left-right and up-down directions, and the first sliding rail 110 is arranged along the front-back direction, and the bottle carrying mechanism 320, the box cover clamping jaw 330 and the liquid filling mechanism 340 are all connected with the mounting frame 380, so that the second lifting and moving mechanism 350, the third front-back moving mechanism 360 and the third left-right moving mechanism 370 can drive the bottle carrying mechanism 320, the box cover clamping jaw 330 and the liquid filling mechanism 340 to move along the front-back, left-right and up-down directions, that is, the bottle carrying mechanism 320 can realize the back-and-forth movement of the culture bottle between the culture bottle tray 150 and the carrier plate 500, the box cover clamping jaw 330 can complete the opening and closing of the box cover, and the liquid filling mechanism 340 can complete the effect of filling the culture box with sample liquid.

In some embodiments of the present utility model, the second elevating moving mechanism 350, the third front-rear moving mechanism 360, the third left-right moving mechanism 370, and the mounting frame 380 are sequentially connected. That is, the third forward and backward movement mechanism 360 is provided on the output end of the second elevating movement mechanism 350, the third leftward and rightward movement mechanism 370 is provided on the output end of the third forward and backward movement mechanism 360, and the mounting frame 380 is provided on the output end of the third leftward and rightward movement mechanism 370. The second lifting and moving mechanism 350 may drive the third front and rear moving mechanism 360, the third left and right moving mechanism 370 and the mounting frame 380 to lift, the third front and rear moving mechanism 360 may drive the third left and right moving mechanism 370 and the mounting frame 380 to move in the front and rear direction, and the third left and right moving mechanism 370 may drive the mounting frame 380 to move in the left and right direction. The second lifting and moving mechanism 350, the third forward and backward moving mechanism 360 and the third leftward and rightward moving mechanism 370 may be screw pairs commonly used in the market, and redundant description is not made here.

In some embodiments of the present utility model, bottle handling mechanism 320 includes bottle cap jaws 321 coupled to a mounting frame 380. The bottle cap clamping jaw 321 can clamp the bottle cap of the culture bottle to clamp the culture bottle. Lid jaw 330 and lid jaw 321 may be motorized jaws, which are common in the market place and are not described in any greater detail herein.

In some embodiments of the present utility model, a fifth left-right moving mechanism 180 is further provided on the machine 100, a bottle body clamping jaw 181 is provided at an output end of the fifth left-right moving mechanism 180, the fifth left-right moving mechanism 180 can drive the bottle body clamping jaw 181 to extend to the carrier plate 500, so that the bottle body clamping jaw 181 clamps a culture bottle on the carrier plate 500, the bottle handling mechanism 320 further includes a second rotation driving mechanism 322, the second rotation driving mechanism 322 is connected with the mounting frame 380, and the bottle cap clamping jaw 321 is provided at an output end of the second rotation driving mechanism 322. The body jaw 181, the cap jaw 321 and the cap jaw 330 may be commercially available electric jaws, and are not described in detail herein. The second rotary drive mechanism 322 may be a third motor.

At first, the bottle cap is screwed on, when the sample liquid in the bottle needs to be pumped out, the fifth left-right moving mechanism 180 drives the bottle body clamping jaw 181 to extend to the carrier plate 500, the bottle body clamping jaw 181 clamps the bottle on the carrier plate 500, and then the second rotary driving mechanism 322 drives the bottle cap clamping jaw 321 to rotate so as to unscrew the bottle cap of the bottle.

Referring to fig. 9 and 10, the culture cassette rack 140 includes a bottom plate structure 141 and a surrounding block 142 connected to each other, the bottom plate structure 141 and the surrounding block 142 form an inner cavity for accommodating the culture cassettes in a stacked manner, the bottom plate structure 141 is connected to the machine 100, and the surrounding block 142 is provided with an opening 143 at the bottom of the side surface near the first slide rail 110 through which a single culture cassette can pass. Multiple cartridges may be stacked in the interior chamber for use, with individual cartridges being discharged from the interior chamber one by one through opening 143, in preparation for sequential movement of cartridges one by one to cartridge stop slot 510.

In some embodiments of the present utility model, the cassette handling mechanism 310 includes a guide rail 311, a sixth left-right moving mechanism 312, and a second pushing plate 313 that is disposed on an output end of the sixth left-right moving mechanism 312 in a liftable manner, wherein the guide rail 311 and the sixth left-right moving mechanism 312 are disposed on the machine 100, two ends of the guide rail 311 are respectively close to the first slide rail 110 and the opening 143, a notch 144 is formed at a bottom of a side surface of the enclosure 142 away from the first slide rail 110, the second pushing plate 313 can pass through the notch 144 to push the culture cassette out of the opening 143 onto the guide rail 311, and the second pushing plate 313 can push the culture cassette to move along the guide rail 311 into the culture cassette limiting groove 510.

The sixth left-right moving mechanism 312 can drive the second push plate 313 to move in the left-right direction. Initially, the second push plate 313 is in a low position, when the second push plate 313 moves to the right of the culture box material frame 140, the second push plate 313 rises to a high position, then the sixth left-right moving mechanism 312 drives the second push plate 313 to move to the left, the second push plate 313 passes through the notch 144 and continues to move, the second push plate 313 can push the culture box at the lowest position in the inner cavity from the opening 143 to the guide rail 311, and then the culture box moves to the culture box limiting groove 510 under the guiding action of the guide rail 311.

In some embodiments, the sixth left-right moving mechanism 312 is connected to the second pushing plate 313 through an electromagnetic lock, the electromagnetic lock is vertically disposed, and an output end of the electromagnetic lock is connected to the second pushing plate 313 and can drive the second pushing plate 313 to rise or fall.

In some embodiments of the present utility model, the base plate structure 141 includes a front base plate and a rear base plate disposed in a front-rear arrangement, where the front base plate and the rear base plate are both disposed on the machine 100, and the front base plate and the rear base plate are both connected to the enclosure 142, and the notch 144 is formed between the front base plate and the rear base plate, and the second push plate 313 can pass through between the front base plate and the rear base plate. Since the notch 144 is formed between the front and rear chassis, the second push plate 313 can pass through between the front and rear chassis, so the second push plate 313 abuts against the culture cassette and drives the culture cassette to move toward the opening 143.

In some embodiments of the present utility model, the liquid injection mechanism 340 includes a third lifting and moving mechanism 341 disposed on the mounting frame 380, a second mounting plate 342 disposed on the third lifting and moving mechanism 341, and a fourth lifting and moving mechanism 343 and a syringe 344 both disposed on the second mounting plate 342, wherein an output end of the fourth lifting and moving mechanism 343 is connected with a piston rod of the syringe 344, and a front end of the syringe 344 can be inserted into a tail end of the suction head.

The fourth lifting and moving mechanism 343 and the syringe 344 are both disposed on the second mounting plate 342, so the third lifting and moving mechanism 341 can drive the syringe 344 to lift by driving the second mounting plate 342 to lift, so that the syringe 344 is inserted into or pulled out from the culture flask, and the syringe 344 can be sleeved with or removed from the suction head, and then is driven by the third front-back moving mechanism 360 and the third left-right moving mechanism 370 to move above the culture box. The output end of the fourth lifting moving mechanism 343 is connected with the piston rod of the cylinder 344, and the cylinder 344 can be driven to suck or spray the sample liquid by driving the piston rod to lift through the fourth lifting moving mechanism 343, so that the effect that the sample liquid enters the suction head or is sprayed out from the suction head is realized.

In some embodiments of the present utility model, the liquid injection mechanism 340 further includes a suction head recovery box and a second baffle 345 both disposed on the machine 100, the second baffle 345 is disposed above the suction head recovery box, and a tail end surface of the suction head may abut against a lower side surface of the second baffle 345. The cylinder 344 carrying the suction head is moved by the third forward and backward movement mechanism 360, the third leftward and rightward movement mechanism 370 and the fourth elevating movement mechanism 343, and when the end face of the rear end of the suction head abuts against the lower side face of the second shutter 345, the cylinder 344 is lifted, the suction head falls off from the cylinder 344 by the blocking of the second shutter 345, and finally the suction head falls into the suction head recovery box.

The second back-and-forth moving mechanism 170 includes a fourth motor, a third driving wheel, a third driven wheel and a third belt, the third driving wheel is disposed at an output end of the fourth motor, the fourth motor and the third driven wheel are both disposed on the machine 100, a linear direction formed by the third driving wheel and the third driven wheel is the same as a length direction of the first sliding rail 110, the third belt is wound on the third driving wheel and the third driven wheel, and the carrier 500 is connected with the third belt. When the fourth motor drives the third belt to rotate, the third belt can drive the carrier 500 to slide on the first sliding rail 110. The sixth left-right moving mechanism 312, the third elevating moving mechanism 341, and the fifth left-right moving mechanism 180 are similar in structure and the same in operation as the second front-rear moving mechanism 170, and redundant description thereof will not be made here. The second lifting and moving mechanism 350, the third front and rear moving mechanism 360 and the third left and right moving mechanism 370 may be screw moving pairs commonly used in the market, and redundant description is not made here. The fourth elevating moving mechanism 343 may be an electric cylinder.

The embodiments of the present utility model have been described in detail with reference to the accompanying drawings, but the present utility model is not limited to the above embodiments, and various changes can be made within the knowledge of one of ordinary skill in the art without departing from the spirit of the present utility model.

Claims

1. Mycoplasma analyzer, characterized in that it comprises:

the machine is provided with a first sliding rail along the front-back direction, a slidable carrier plate is arranged on the first sliding rail, a culture box limiting groove and a culture bottle limiting hole are formed in the carrier plate, the front end of the first sliding rail is a culture box feeding station, a fifth left-right moving mechanism is arranged on the machine, and a culture box material rack, a culture bottle material tray and a suction head material tray are arranged on the periphery of the first sliding rail;

the culture box making device comprises a box carrying mechanism, a bottle carrying mechanism, box cover clamping jaws, a liquid filling mechanism, a second lifting moving mechanism, a third front-back moving mechanism, a third left-right moving mechanism and a mounting frame, wherein the box carrying mechanism, the bottle carrying mechanism, the box cover clamping jaws and the liquid filling mechanism are all arranged in a box limiting groove of the machine table, the third front-back moving mechanism, the third left-right moving mechanism and the mounting frame are all arranged on the second lifting moving mechanism, the third front-back moving mechanism and the third left-right moving mechanism can respectively drive the mounting frame to move in the vertical direction, the bottle carrying mechanism, the box cover clamping jaws and the liquid filling mechanism are all connected with the mounting frame, the bottle carrying mechanism can carry a culture box on a culture box material frame into the culture box limiting groove, the bottle carrying mechanism can be movably arranged above the first sliding rail and the culture box material disc, the bottle cover carrying mechanism can clamp a culture bottle and can clamp a bottle cover in the culture box from the upper side, the bottle cover clamping jaw can be rotatably driven by the bottle cover clamping jaw driving mechanism to the bottle cover driving mechanism, the bottle cover driving mechanism can be rotatably driven by the bottle cover driving jaw driving mechanism to the bottle cover driving plate driving the bottle cover driving mechanism to the bottle cover driving jaw driving mechanism to the bottle cover driving mechanism to the bottle cover driving jaw driving mechanism. The box cover clamping jaw can clamp and lift the box cover of the culture box, the liquid injection mechanism is arranged above the space between the first sliding rail and the suction head charging tray in a lifting manner, the liquid injection mechanism can carry the suction head on the suction head charging tray and inject sample liquid in the culture bottle into the culture box through the suction head, and the culture box manufacturing device is used for manufacturing the culture box and placing the completed culture box in the culture box limiting groove; the incubator is arranged on the machine table and is provided with a chamber and a box door capable of sealing the chamber;

the culture box transferring mechanism is arranged on the machine table, a supporting plate is arranged on the culture box transferring mechanism, and the supporting plate can support the culture box on the culture box feeding station and transfer the culture box into the cavity;

and the image pickup device is connected with the culture box transferring mechanism and faces the supporting plate to photograph the mixture in the culture box.

2. The mycoplasma analyzer of claim 1, wherein: the incubator is equipped with heating mechanism and vertical rotatable runing rest in the cavity, be equipped with the backup pad that the interval set up about the multilayer on the runing rest, be equipped with a plurality of cultivation box fixed slots in the backup pad, the layer board can hold up the cultivation box and will the cultivation box shifts to the cultivation box fixed slot.

3. The mycoplasma analyzer of claim 2, wherein: the incubator comprises an incubator body, an incubator door, an incubator loading station, an incubator transferring mechanism, a support plate, a limiting plate, a support plate and a support plate, wherein the incubator door is arranged on the front side surface of the incubator body, the incubator door is arranged above the incubator loading station, the incubator transferring mechanism comprises a first lifting moving mechanism connected with the incubator body, a first mounting plate arranged on the output end of the first lifting moving mechanism, a first front-back moving mechanism arranged on the first mounting plate, the support plate is connected with the first mounting plate, the output end of the first front-back moving mechanism is provided with the limiting plate, the limiting plate is arranged above the support plate, a containing cavity for containing the incubator body can be formed between the limiting plate and the support plate, and the opening of the containing cavity faces to the left side.

4. A mycoplasma analyzer according to claim 3, wherein: the culture box transfer mechanism further comprises a first left-right moving mechanism arranged on the first mounting plate, a first baffle is connected to the output end of the first left-right moving mechanism, the first baffle faces the opening of the accommodating cavity, and the first baffle can be abutted to the left side face of the culture box.

5. The mycoplasma analyzer of claim 4, wherein: the machine is in the left side of cultivateing box material loading workstation is equipped with second left and right movement mechanism, be equipped with first push pedal on the output of second left and right movement mechanism, first push pedal can with cultivate on the box material loading workstation cultivate the box impels hold the chamber.

6. The mycoplasma analyzer of claim 5, wherein: the support plate is made of transparent materials, the camera device is connected with the first mounting plate through the connecting plate, and the camera device is located below the support plate.

7. The mycoplasma analyzer of claim 2, wherein: the incubator is characterized in that a supporting table is arranged on the machine table and is positioned above the side of the incubator feeding station, the incubator is arranged on the supporting table, a first rotary driving mechanism is arranged on the supporting table, and the output end of the first rotary driving mechanism extends into the incubator and is connected with the rotary support.

8. The mycoplasma analyzer of claim 7, wherein: the rotary support comprises a hollow shell, ventilation holes are formed in the peripheral wall of the shell, and the heating mechanism is arranged in the shell.

9. The mycoplasma analyzer of claim 2, wherein: the backup pad is discoid, the diapire of cultivateing the box fixed slot is equipped with dodges the hole, dodge the hole and supply the layer board stretches into, cultivate the box fixed slot with dodge the opening in hole all locates on the outer circumference wall of backup pad, the layer board with cultivate the box can stretch into respectively dodge the hole with cultivate in the box fixed slot.

10. The mycoplasma analyzer according to claim 1 or 2, wherein: the machine is also provided with a waste collection tank body, and the culture box after cultivation and detection can be thrown into the waste collection tank body through the culture box transfer mechanism.