CN113081901A - 一种多功能的弱酸性洁面水及其制备方法 - Google Patents
一种多功能的弱酸性洁面水及其制备方法 Download PDFInfo
- Publication number
- CN113081901A CN113081901A CN202110368502.XA CN202110368502A CN113081901A CN 113081901 A CN113081901 A CN 113081901A CN 202110368502 A CN202110368502 A CN 202110368502A CN 113081901 A CN113081901 A CN 113081901A
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- CN
- China
- Prior art keywords
- lanolin
- peg
- glucoside
- glycerides
- multifunctional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000001815 facial effect Effects 0.000 title claims abstract description 34
- 238000002360 preparation method Methods 0.000 title abstract description 9
- 239000004166 Lanolin Substances 0.000 claims abstract description 109
- 229940039717 lanolin Drugs 0.000 claims abstract description 109
- 235000019388 lanolin Nutrition 0.000 claims abstract description 109
- 125000005456 glyceride group Chemical group 0.000 claims abstract description 48
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 35
- 229930182478 glucoside Natural products 0.000 claims abstract description 31
- -1 alkyl glucoside Chemical class 0.000 claims abstract description 30
- PHOQVHQSTUBQQK-SQOUGZDYSA-N D-glucono-1,5-lactone Chemical compound OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O PHOQVHQSTUBQQK-SQOUGZDYSA-N 0.000 claims abstract description 21
- 235000012209 glucono delta-lactone Nutrition 0.000 claims abstract description 21
- 229960003681 gluconolactone Drugs 0.000 claims abstract description 21
- 230000002378 acidificating effect Effects 0.000 claims abstract description 20
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical class O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 18
- 150000003839 salts Chemical class 0.000 claims abstract description 14
- 238000000034 method Methods 0.000 claims abstract description 10
- 150000002148 esters Chemical class 0.000 claims abstract description 7
- 229920005862 polyol Polymers 0.000 claims abstract description 6
- 150000003077 polyols Chemical class 0.000 claims abstract description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 36
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 18
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 17
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical compound C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 claims description 12
- 239000003921 oil Substances 0.000 claims description 11
- 235000019198 oils Nutrition 0.000 claims description 11
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims description 9
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 9
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 9
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims description 9
- PHYFQTYBJUILEZ-IUPFWZBJSA-N triolein Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC PHYFQTYBJUILEZ-IUPFWZBJSA-N 0.000 claims description 9
- 239000001993 wax Substances 0.000 claims description 9
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 8
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims description 8
- 235000004977 Brassica sinapistrum Nutrition 0.000 claims description 6
- JDRSMPFHFNXQRB-CMTNHCDUSA-N Decyl beta-D-threo-hexopyranoside Chemical compound CCCCCCCCCCO[C@@H]1O[C@H](CO)C(O)[C@H](O)C1O JDRSMPFHFNXQRB-CMTNHCDUSA-N 0.000 claims description 6
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 6
- RADKZDMFGJYCBB-UHFFFAOYSA-N Pyridoxal Chemical compound CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 claims description 6
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 claims description 6
- 229940073499 decyl glucoside Drugs 0.000 claims description 6
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 6
- 229940074774 glycyrrhizinate Drugs 0.000 claims description 6
- BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical compound OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 claims description 6
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 6
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims description 6
- 239000011701 zinc Substances 0.000 claims description 6
- 229910052725 zinc Inorganic materials 0.000 claims description 6
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 5
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- 239000004480 active ingredient Substances 0.000 claims description 5
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- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 claims description 4
- IIRDTKBZINWQAW-UHFFFAOYSA-N hexaethylene glycol Chemical compound OCCOCCOCCOCCOCCOCCO IIRDTKBZINWQAW-UHFFFAOYSA-N 0.000 claims description 4
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 claims description 4
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- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 4
- 229960004889 salicylic acid Drugs 0.000 claims description 4
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 claims description 4
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 claims description 3
- PAEMERHSTIDLSE-QMCAAQAGSA-N (2r,3r,4s,5s,6r)-2-hexadecoxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound CCCCCCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O PAEMERHSTIDLSE-QMCAAQAGSA-N 0.000 claims description 3
- MPDGHEJMBKOTSU-WFJWTYAKSA-N (2s,4as,6as,6br,10s,12as)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid Chemical compound C12C(=O)C=C3C4C[C@@](C)(C(O)=O)CC[C@]4(C)CC[C@@]3(C)[C@]1(C)CCC1[C@]2(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-WFJWTYAKSA-N 0.000 claims description 3
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- ALVZNPYWJMLXKV-UHFFFAOYSA-N 1,9-Nonanediol Chemical compound OCCCCCCCCCO ALVZNPYWJMLXKV-UHFFFAOYSA-N 0.000 claims description 3
- AEQDJSLRWYMAQI-UHFFFAOYSA-N 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline Chemical compound C1CN2CC(C(=C(OC)C=C3)OC)=C3CC2C2=C1C=C(OC)C(OC)=C2 AEQDJSLRWYMAQI-UHFFFAOYSA-N 0.000 claims description 3
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- OCUCCJIRFHNWBP-IYEMJOQQSA-L Copper gluconate Chemical compound [Cu+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O OCUCCJIRFHNWBP-IYEMJOQQSA-L 0.000 claims description 3
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Abstract
本发明公开了一种多功能的弱酸性洁面水及其制备方法，属于化妆品领域，包括以下质量百分比的组分：水：30wt％～90wt％、多元醇：0.001％wt～50wt％、烷基葡糖苷：0.001wt％～50wt％、葡糖酸内酯或葡糖酸内酯的盐：0.001wt％～15wt％、甘草酸的盐或酯：0.001wt％～5wt％、水解羊毛脂或甘油酯类：0.001wt％～5wt％。洁面水具有洁面、卸妆、修复三效合一的特征，更特别地作为弱酸性配方用于修复皮肤固有的酸性屏障和提高皮肤水化，有助于弱化皮肤清洁过程中的角质细胞肿胀和脱水过程，减轻皮肤刺激，洗后不干燥、不紧绷。
Description
技术领域
本发明属于化妆品领域，具体涉及一种多功能的弱酸性洁面水及其制备方法。
背景技术
洁面水是人们采用洗涤方式去除人体面部表面附着的皮脂、屑片等生理代谢产物以及污垢、化妆品残留物等时所使用的清洁产品。早在一百多年以前科学家就已经发现人体皮肤表面是弱酸性的(pH4至6)，但是现有技术中的皮肤清洁产品大都是碱性的，清洁后必然导致皮肤表面pH的碱性化，导致皮肤干燥、紧绷和外油内干，碱性清洁剂与护肤品也是导致皮肤敏感的重要因素。
对清洁剂的pH值与皮肤刺激性的相关性研究发现，大多数推荐给敏感皮肤的产品都有相当大的刺激作用，这与产品的pH值有关。包括清洁后出现的皮肤敏感、干燥、紧绷、红斑、脱屑、皲裂，产品的pH值越高，对皮肤的刺激性越大，越来越多的皮肤科医生推荐弱酸性的、与皮肤生理pH值一致的多效洁面水用于敏感肌肤护理。
因此，需开发一种多功能的弱酸性洁面水及其制备方法，作为弱酸性配方用于修复皮肤固有的酸性屏障和提高皮肤水化，同时兼具洁面、卸妆、修复三效合一。
发明内容
本发明的目的在于提供一种多功能的弱酸性洁面水及其制备方法，以解决皮肤清洁剂的碱性导致皮肤干燥、紧绷和外油内干，以及清洁剂功能单一的问题。
为实现本发明目的，采用的技术方案为：一种多功能的弱酸性洁面水，包括以下质量百分比的组分：水：30wt％～90wt％、多元醇：0.001％wt～50wt％、烷基葡糖苷：0.001wt％～50wt％、葡糖酸内酯或葡糖酸内酯的盐：0.001wt％～15wt％、甘草酸的盐或酯：0.001wt％～5wt％、水解羊毛脂或甘油酯类：0.001wt％～5wt％。
作为进一步可选方案，所述多元醇为以下中的一种或多种：双丙甘醇、丙醇、异丙醇、丙二醇、1,3-丙二醇、甘油、双甘油、1,2-丁二醇、1,4-丁二醇、2,3-丁二醇、1,2-戊二醇、1,5-戊二醇、二甘醇、三甘醇、1,2-己二醇、1,6-己二醇、壬二醇、1,9-壬二醇、木糖醇、乳糖醇、辛二醇、辛甘醇、戊二醇、乙醇、乙二醇、SD乙醇-38B、SD乙醇-38C、SD乙醇-39C、SD乙醇40、SD乙醇40-A、SD乙醇40-B、变性乙醇。
作为进一步可选方案，所述烷基葡糖苷选自C8-14烷基葡糖苷、C12-16烷基葡糖苷、C12-18烷基葡糖苷、C12-2-烷基葡糖苷、十六烷基葡糖苷、辛基葡糖苷、癸基葡糖苷、辛基/癸基葡糖苷、辛基聚二甲基硅氧烷乙氧基葡糖苷、椰油基葡糖苷、乙基葡糖苷、异硬脂基葡糖苷、月桂基葡糖苷中的一种或多种。
作为进一步可选方案，所述葡糖酸内酯的盐为以下中的任意一种：所述葡糖酸内酯的盐包括葡糖酸钙、葡糖酸钴、葡糖酸钾、葡糖酸镁、葡糖酸锰、葡糖酸钠、葡糖酸铜、葡糖酸锌、葡糖酸亚铁。
作为进一步可选方案，所述甘草酸的盐或酯为以下中的任意一种：甘草酸铵、甘草酸锌、甘草酸钾、甘草酸二钾、甘草酸二钠、甘草酸三钠、甘草亭酸、甘草亭酸锌、甘草亭酸硬脂酸酯、琥珀酰甘草亭酸二钠、硬脂醇甘草亭酸酯、甘草类黄酮。
作为进一步可选方案，所述水解羊毛脂选自以下天然羊毛脂及其衍生物中的任意一种：羊毛脂、羊毛脂蜡、羊毛脂酸、羊毛脂油、氢化羊毛脂、乙酰化羊毛脂、PEG-5羊毛脂、PEG-7羊毛脂、PEG-20羊毛脂、PEG-24羊毛脂、PEG-27羊毛脂、PEG-30羊毛脂、PEG-35羊毛脂、PEG-40羊毛脂、PEG-50羊毛脂、PEG-55羊毛脂、PEG-60羊毛脂、PEG-75羊毛脂、PEG-85羊毛脂、PEG-100羊毛脂、PEG-150羊毛脂、PEG-20氢化羊毛脂、PEG-40氢化羊毛脂、PEG-70氢化羊毛脂、PEG-75羊毛脂蜡、PEG-75羊毛脂油、PPG-12-PEG-50羊毛脂、PPG-12-PEG-65羊毛脂油、PPG-2羊毛脂醇醚、PPG-20-PEG-20氢化羊毛脂、PPG-5羊毛脂醇醚、PPG-5羊毛脂蜡、羟基化羊毛脂、氢化羊毛脂。
作为进一步可选方案，所述甘油脂类选自以下中的任意一种或多种：辛酸/癸酸甘油酯类、椰油酸甘油酯类、异硬脂酸/肉豆蔻酸甘油酯类、油菜籽油甘油酯类、油酸/亚油酸/亚麻酸聚甘油酯类、月桂酸/肉豆蔻酸/棕榈酸/硬脂酸甘油酯类、植物甾醇低芥酸菜子油甘油酯类、棕榈油甘油酯、阿魏酰大豆甘油酯、大豆甘油酯类、单酸甘油酯柠檬酸酯、红花油酸甘油酯、葵花籽油甘油酯、葵花籽油甘油酯类、棉籽油酸甘油酯、牛脂酸甘油酯、牛脂酸甘油酯类、妥尔油甘油酯类、小麦胚芽油甘油酯类、PEG-4辛酸/癸酸甘油酯类、PEG-6辛酸/癸酸甘油酯类、PEG-7辛酸/癸酸甘油酯类、PEG-8辛酸/癸酸甘油酯类。
作为进一步可选方案，其组分还包括：泛醇、肌醇、肌醇六磷酸、烟酰胺、吡哆素、吡哆醛、甜菜碱、水杨酸、壬二酸、燕麦活性成分中的任一种或几种组合。
本发明还提供一种如上任一项所述的多功能的弱酸性洁面水的制备方法，包括以下步骤：
1)准备原料；
2)按质量百分比称取各组分；
3)在常温下分别将各组分加入水相锅，混合均匀；
4)半成品检验，检验pH值为4～6；
5)检验合格后依次进行灌装、入库、包装。
全部采用常温下的冷配方工艺，无需加热乳化。
本发明的有益效果是：
1.本发明的洁面水是一种低泡的水性清洁产品，对皮肤温和无刺激，具有洁面、卸妆、修复三效合一的特效；
2.本发明采用非乳化的冷配方工艺，无需加热和乳化，可降低生产成本并防止活性成分的失活；
3.本发明的弱酸性配方可作为pH调节剂用于修复皮肤固有的酸性屏障，防止皮肤表面pH值的碱性化，最终产品的pH值为4至6，有效防止碱性清洁剂所致的过度去脂化；
4.本发明的洁面水可作为保湿剂用于提高皮肤水化，有助于弱化皮肤洁面过程中的角质细胞肿胀与脱水过程，减轻传统碱性清洁剂的皮肤刺激性，洗后不干燥、不紧绷；
5.本发明的洁面水在不含防腐剂的情况下可以在常温贮存36月以上并保持稳定，无微生物生长。
附图说明
为了更清楚地说明本发明的技术方案，下面将对实施例描述中所需要使用的附图作简单地介绍，应当理解的是，下面描述中的附图是本发明的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1是本发明实施例提供的多功能的弱酸性洁面水的皮肤水分测试比较示意图。
具体实施方式
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明的实施例，本领域普通技术人员在没有做出创造性劳动的前提下所获得所有其他实施例，都属于本发明的保护范围。可以理解的是，附图仅仅提供参考与说明用，并非用来对本发明加以限制。
除非另有定义，本文所使用的所有的技术和科学术语与属于本发明的技术领域的技术人员通常理解的含义相同。本文中在本发明的说明书中所使用的术语只是为了描述具体的实施例的目的，不是旨在于限制本发明。
下面结合附图及具体实施例对本发明作进一步阐述。
本发明提供的多功能的弱酸性洁面水，包括以下质量百分比的组分：水：30wt％～90wt％、多元醇：0.001％wt～50wt％、烷基葡糖苷：0.001wt％～50wt％、葡糖酸内酯或葡糖酸内酯的盐：0.001wt％～15wt％、甘草酸的盐或酯：0.001wt％～5wt％、水解羊毛脂或甘油酯类：0.001wt％～5wt％。
多元醇和水解羊毛脂作为保湿剂；烷基葡糖苷作为表面活性剂；葡糖酸内酯或葡糖酸内酯的盐作为pH调节剂和稳定剂。
多元醇为以下中的一种或多种：双丙甘醇、丙醇、异丙醇、丙二醇、1,3-丙二醇、甘油、双甘油、1,2-丁二醇、1,4-丁二醇、2,3-丁二醇、1,2-戊二醇、1,5-戊二醇、二甘醇、三甘醇、1,2-己二醇、1,6-己二醇、壬二醇、1,9-壬二醇、木糖醇、乳糖醇、辛二醇、辛甘醇、戊二醇、乙醇、乙二醇、SD乙醇-38B、SD乙醇-38C、SD乙醇-39C、SD乙醇40、SD乙醇40-A、SD乙醇40-B、变性乙醇。
烷基葡糖苷选自C8-14烷基葡糖苷、C12-16烷基葡糖苷、C12-18烷基葡糖苷、C12-2-烷基葡糖苷、十六烷基葡糖苷、辛基葡糖苷、癸基葡糖苷、辛基/癸基葡糖苷、辛基聚二甲基硅氧烷乙氧基葡糖苷、椰油基葡糖苷、乙基葡糖苷、异硬脂基葡糖苷、月桂基葡糖苷中的一种或多种。
葡糖酸内酯的盐为以下中的任意一种：所述葡糖酸内酯的盐包括葡糖酸钙、葡糖酸钴、葡糖酸钾、葡糖酸镁、葡糖酸锰、葡糖酸钠、葡糖酸铜、葡糖酸锌、葡糖酸亚铁。
甘草酸的盐或酯为以下中的任意一种：甘草酸铵、甘草酸锌、甘草酸钾、甘草酸二钾、甘草酸二钠、甘草酸三钠、甘草亭酸、甘草亭酸锌、甘草亭酸硬脂酸酯、琥珀酰甘草亭酸二钠、硬脂醇甘草亭酸酯、甘草类黄酮。
水解羊毛脂选自以下天然羊毛脂及其衍生物中的任意一种：羊毛脂、羊毛脂蜡、羊毛脂酸、羊毛脂油、氢化羊毛脂、乙酰化羊毛脂、PEG-5羊毛脂、PEG-7羊毛脂、PEG-20羊毛脂、PEG-24羊毛脂、PEG-27羊毛脂、PEG-30羊毛脂、PEG-35羊毛脂、PEG-40羊毛脂、PEG-50羊毛脂、PEG-55羊毛脂、PEG-60羊毛脂、PEG-75羊毛脂、PEG-85羊毛脂、PEG-100羊毛脂、PEG-150羊毛脂、PEG-20氢化羊毛脂、PEG-40氢化羊毛脂、PEG-70氢化羊毛脂、PEG-75羊毛脂蜡、PEG-75羊毛脂油、PPG-12-PEG-50羊毛脂、PPG-12-PEG-65羊毛脂油、PPG-2羊毛脂醇醚、PPG-20-PEG-20氢化羊毛脂、PPG-5羊毛脂醇醚、PPG-5羊毛脂蜡、羟基化羊毛脂、氢化羊毛脂。
甘油脂类选自以下中的任意一种或多种：辛酸/癸酸甘油酯类、椰油酸甘油酯类、异硬脂酸/肉豆蔻酸甘油酯类、油菜籽油甘油酯类、油酸/亚油酸/亚麻酸聚甘油酯类、月桂酸/肉豆蔻酸/棕榈酸/硬脂酸甘油酯类、植物甾醇低芥酸菜子油甘油酯类、棕榈油甘油酯、阿魏酰大豆甘油酯、大豆甘油酯类、单酸甘油酯柠檬酸酯、红花油酸甘油酯、葵花籽油甘油酯、葵花籽油甘油酯类、棉籽油酸甘油酯、牛脂酸甘油酯、牛脂酸甘油酯类、妥尔油甘油酯类、小麦胚芽油甘油酯类、PEG-4辛酸/癸酸甘油酯类、PEG-6辛酸/癸酸甘油酯类、PEG-7辛酸/癸酸甘油酯类、PEG-8辛酸/癸酸甘油酯类。
本洁面水的组分还包括：泛醇、肌醇、肌醇六磷酸、烟酰胺、吡哆素、吡哆醛、甜菜碱、水杨酸、壬二酸、燕麦活性成分中的任一种或几种组合。作为皮肤美容调理活性成分。
各组分的含量可根据与其它成分的平衡来适当设定，本发明的洁面水具有温和、低泡性和适当的清洁能力，与传统碱性清洁剂相比较对皮脂膜的影响轻微，有助于防止过度去脂化和脂质屏障受损。
实施例1
本实施例的洁面水各组分如下：水：76wt％、双丙甘醇：10wt％、烷基葡糖苷：10wt％、葡糖酸内酯：1.5wt％、甘草酸二钾：1wt％、水解羊毛脂：1.5wt％。可用作敏感肌肤的多效洁面水的制备。
实施例2
本实施例的洁面水各组分如下：水：74.5wt％、双丙甘醇：10wt％、烷基葡糖苷：10wt％、葡糖酸内酯：2wt％、甘草酸二钾：0.5wt％、PEG-6辛酸/癸酸甘油酯类：3wt％。可用作不含羊毛脂的多效洁面水的制备。
实施例3
本实施例的洁面水各组分如下：水：75wt％、双丙甘醇：10wt％、烷基葡糖苷：10wt％、葡糖酸内酯：2wt％、甘草酸铵：0.5wt％、油酸甘油酯：2wt％、泛醇：0.5wt％。可用作面部及头皮清洁的多效洁面水的制备。
实施例4
本实施例的洁面水各组分如下：水：71.2wt％、双丙甘醇：10wt％、烷基葡糖苷：10wt％、葡糖酸内酯：3wt％、甘草酸铵：0.3wt％、辛酸/癸酸甘油酯类：1.5wt％、水杨酸：0.5wt％、烟酰胺：2wt％、肌醇：1wt％、泛醇：0.5wt％。可用作油性、易生粉刺肌肤的多效洁面水的制备。
实施例5
本实施例的洁面水各组分如下：水：82.7wt％、双丙甘醇：5wt％、烷基葡糖苷：5wt％、葡糖酸内酯：1wt％、甘草酸铵：0.3wt％、椰油酸甘油酯类：3wt％、燕麦仁提取物：3wt％。可用作婴幼儿多效洁面水的制备。
本发明的多效洁面水试验：
受试者：5名研究人员，年龄25～55岁，以室内工作为主，无大量日晒史、无光感性疾病史；测量部位无皮肤病、色素沉着、瘢痕或可影响皮肤的全身疾病。
试验材料：取本发明的多效洁面水各200ml，通过添加不同剂量的10％NaOH溶液，分别调制出pH值为4.5、5.5、7.0和7.5的洁面水。
试验设备：角质层含水量测量仪。
试验方法：采用间接法测定皮肤含水量。以本实验室5名研究人员作为受试者，在受试者前臂内侧对等位置各选取一块2cm×2cm大小的皮肤作为试验区并标记，测定皮肤清洁前、清洁后立即及清洁后每隔30分钟测定皮肤含水量，取5名受试者的平均值为记录结果，如下表1。皮肤水分测试比较示意图如图1。
表1、皮肤含水量(acu)
| 时间(min) | Before | 0 | 30 | 60 | 90 | 120 | 150 | 180 |
| 洁面水：pH4.5 | 48.3 | 80.8 | 36.1 | 37.1 | 38.2 | 43.1 | 45.5 | 48.1 |
| 洁面水：pH5.5 | 47.3 | 81.4 | 36.5 | 38.8 | 37.9 | 39.8 | 41.1 | 45.4 |
| 洁面水：pH7.0 | 49.5 | 83.7 | 29.8 | 31.9 | 35.3 | 37.1 | 40.9 | 42.6 |
| 洁面水：pH7.5 | 49.7 | 85.2 | 24.4 | 24.6 | 29.2 | 30.6 | 36.2 | 39.1 |
通过表1可以发现：当组合物的pH值为4至6时，皮肤清洁后(0分钟)角质层水化、肿胀明显低于pH值为7或7.5时；当组合物的pH值为4至6时，皮肤清洁后30至180分钟引起的角质层脱水也明显低于pH值为7或7.5时。实验数据说明，本发明的组合物弱化了皮肤洁面过程中的角质细胞肿胀与脱水。
本洁面水在常温贮存36个月无微生物生长。
多效洁面水微生物挑战性试验：
将具有以下菌种的组合物加入洁面水，各菌种的抑菌圈直径如表2。
表2、抑菌圈直径(mm)：
从表2的抑菌圈直径可以看出，本发明的组合物对常见的革兰阳性菌、阴性菌、真菌有一定的抑菌活性，所以，在未添加反腐剧的情况下常温储存36个月稳定且无微生物生长。
本发明实施例还提供一种如上任一项所述的多功能的弱酸性洁面水的制备方法，全部采用常温下的冷配方工艺，无需加热乳化，包括以下步骤：
1)准备原料；
2)按质量百分比称取各组分；
3)在常温下分别将各组分加入水相锅，混合均匀；
4)半成品检验，检验pH值为4～6；
5)检验合格后依次进行灌装、入库、包装。
与现有技术相比，本发明的制备方法制成的洁面水对皮肤温和无刺激，可作为pH调节剂用于修复皮肤固有的酸性屏障，防止皮肤表面pH值的碱性化，亦可作为保湿剂用于提高皮肤水化，有助于弱化皮肤洁面过程中的角质细胞肿胀与脱水过程，减轻传统碱性清洁剂的皮肤刺激性，洗后不干燥、不紧绷，同时具有洁面、卸妆、修复三效合一的特效。
本发明不局限于上述可选实施方式，应当理解，本领域的普通技术无需创造性劳动就可以根据本发明的构思作出诸多修改和变化。因此，凡本技术领域中技术人员依本发明的构思在现有技术的基础上通过逻辑分析、推理或者有限的实验可以得到的技术方案，皆应在由权利要求书所确定的保护范围内。
Claims (9)
1.一种多功能的弱酸性洁面水，其特征在于，包括以下质量百分比的组分：水：30wt％～90wt％、多元醇：0.001％wt～50wt％、烷基葡糖苷：0.001wt％～50wt％、葡糖酸内酯或葡糖酸内酯的盐：0.001wt％～15wt％、甘草酸的盐或酯：0.001wt％～5wt％、水解羊毛脂或甘油酯类：0.001wt％～5wt％。
2.根据权利要求1所述的多功能的弱酸性洁面水，其特征在于，所述多元醇为以下中的一种或多种：双丙甘醇、丙醇、异丙醇、丙二醇、1,3-丙二醇、甘油、双甘油、1,2-丁二醇、1,4-丁二醇、2,3-丁二醇、1,2-戊二醇、1,5-戊二醇、二甘醇、三甘醇、1,2-己二醇、1,6-己二醇、壬二醇、1,9-壬二醇、木糖醇、乳糖醇、辛二醇、辛甘醇、戊二醇、乙醇、乙二醇、SD乙醇-38B、SD乙醇-38C、SD乙醇-39C、SD乙醇40、SD乙醇40-A、SD乙醇40-B、变性乙醇。
3.根据权利要求1所述的多功能的弱酸性洁面水，其特征在于，所述烷基葡糖苷选自C8-14烷基葡糖苷、C12-16烷基葡糖苷、C12-18烷基葡糖苷、C12-2-烷基葡糖苷、十六烷基葡糖苷、辛基葡糖苷、癸基葡糖苷、辛基/癸基葡糖苷、辛基聚二甲基硅氧烷乙氧基葡糖苷、椰油基葡糖苷、乙基葡糖苷、异硬脂基葡糖苷、月桂基葡糖苷中的一种或多种。
4.根据权利要求1所述的多功能的弱酸性洁面水，其特征在于，所述葡糖酸内酯的盐为以下中的任意一种：所述葡糖酸内酯的盐包括葡糖酸钙、葡糖酸钴、葡糖酸钾、葡糖酸镁、葡糖酸锰、葡糖酸钠、葡糖酸铜、葡糖酸锌、葡糖酸亚铁。
5.根据权利要求1所述的多功能的弱酸性洁面水，其特征在于，所述甘草酸的盐或酯为以下中的任意一种：甘草酸铵、甘草酸锌、甘草酸钾、甘草酸二钾、甘草酸二钠、甘草酸三钠、甘草亭酸、甘草亭酸锌、甘草亭酸硬脂酸酯、琥珀酰甘草亭酸二钠、硬脂醇甘草亭酸酯、甘草类黄酮。
6.根据权利要求1所述的多功能的弱酸性洁面水，其特征在于，所述水解羊毛脂选自以下天然羊毛脂及其衍生物中的任意一种：羊毛脂、羊毛脂蜡、羊毛脂酸、羊毛脂油、氢化羊毛脂、乙酰化羊毛脂、PEG-5羊毛脂、PEG-7羊毛脂、PEG-20羊毛脂、PEG-24羊毛脂、PEG-27羊毛脂、PEG-30羊毛脂、PEG-35羊毛脂、PEG-40羊毛脂、PEG-50羊毛脂、PEG-55羊毛脂、PEG-60羊毛脂、PEG-75羊毛脂、PEG-85羊毛脂、PEG-100羊毛脂、PEG-150羊毛脂、PEG-20氢化羊毛脂、PEG-40氢化羊毛脂、PEG-70氢化羊毛脂、PEG-75羊毛脂蜡、PEG-75羊毛脂油、PPG-12-PEG-50羊毛脂、PPG-12-PEG-65羊毛脂油、PPG-2羊毛脂醇醚、PPG-20-PEG-20氢化羊毛脂、PPG-5羊毛脂醇醚、PPG-5羊毛脂蜡、羟基化羊毛脂、氢化羊毛脂。
7.根据权利要求1所述的多功能的弱酸性洁面水，其特征在于，所述甘油脂类选自以下中的任意一种或多种：辛酸/癸酸甘油酯类、椰油酸甘油酯类、异硬脂酸/肉豆蔻酸甘油酯类、油菜籽油甘油酯类、油酸/亚油酸/亚麻酸聚甘油酯类、月桂酸/肉豆蔻酸/棕榈酸/硬脂酸甘油酯类、植物甾醇低芥酸菜子油甘油酯类、棕榈油甘油酯、阿魏酰大豆甘油酯、大豆甘油酯类、单酸甘油酯柠檬酸酯、红花油酸甘油酯、葵花籽油甘油酯、葵花籽油甘油酯类、棉籽油酸甘油酯、牛脂酸甘油酯、牛脂酸甘油酯类、妥尔油甘油酯类、小麦胚芽油甘油酯类、PEG-4辛酸/癸酸甘油酯类、PEG-6辛酸/癸酸甘油酯类、PEG-7辛酸/癸酸甘油酯类、PEG-8辛酸/癸酸甘油酯类。
8.根据权利要求1所述的多功能的弱酸性洁面水，其特征在于，其组分还包括：泛醇、肌醇、肌醇六磷酸、烟酰胺、吡哆素、吡哆醛、甜菜碱、水杨酸、壬二酸、燕麦活性成分中的任一种或几种组合。
9.一种如权利要求1-8任一项所述的多功能的弱酸性洁面水的制备方法，其特征在于，包括以下步骤：
1)准备原料；
2)按质量百分比称取各组分；
3)在常温下分别将各组分加入水相锅，混合均匀；
4)半成品检验，检验pH值为4～6；
5)检验合格后依次进行灌装、入库、包装。
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