CN113073039B - Colorimetric blood culture interpretation method and device - Google Patents
Colorimetric blood culture interpretation method and device Download PDFInfo
- Publication number
- CN113073039B CN113073039B CN202110310310.3A CN202110310310A CN113073039B CN 113073039 B CN113073039 B CN 113073039B CN 202110310310 A CN202110310310 A CN 202110310310A CN 113073039 B CN113073039 B CN 113073039B
- Authority
- CN
- China
- Prior art keywords
- value
- critical point
- blood culture
- judging whether
- rgb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
Abstract
The invention discloses a colorimetric blood culture interpretation method and a colorimetric blood culture interpretation device, wherein the method comprises the following steps: judging whether the bacteria culture duration reaches a first preset value; if so, acquiring RGB values of the bottom of the blood culture bottle, and judging whether the conditions for converting the RGB values into HSV values are met; if yes, converting the RGB value into an HSV value; acquiring a first change critical point and a second change critical point corresponding to the H value; acquiring H values corresponding to the first change critical point and the second change critical point, and judging whether the difference value of the H values corresponding to the first change critical point and the second change critical point is greater than a second preset value; if yes, judging that the current moment is a positive judgment moment, and judging whether the S value is more than or equal to the H value; if so, the blood culture result is judged to be a positive result. Compared with the prior art, the method and the device not only improve the detection accuracy of the blood culture result, but also shorten the detection time, thereby improving the detection efficiency.
Description
Technical Field
The invention relates to the field of biological detection, in particular to a colorimetric blood culture interpretation method and a colorimetric blood culture interpretation device.
Background
The colorimetry blood culture bottle changes the bottle internal pressure through produced carbon dioxide or other gases when the cultivation of inoculation bacterium in the liquid medium in the bottle breeds to promote carbon dioxide and see through the porous silica gel encapsulation membrane in bottle bottom in the bottle, contact the biochemical sensor who encapsulates in silica gel and change colour, blood culture bottle rubber bottom is grey in the colour before the use, and RGB three-colour numerical value is close.
The blood culture bottle begins to change color during use, changes from middle gray to yellow, and finally becomes dark yellow. Since the color change is irreversible, the presence of bacteria in the culture solution in the flask can be determined by the color change.
The clinical judgment method for the blood culture result of the colorimetry mostly adopts a threshold value method of color cumulative change numerical values, namely, when the color changes to a specific value, a positive result or a negative result is judged by a matched instrument.
Specifically, after a large amount of data is collected and collated, growth curves of various bacteria are obtained and accord with the curve laws shown in fig. 2 to 4.
As shown in fig. 3: and ab stage, which is an external factor wave band stage, is just a stage of putting the strain into a blood culture instrument for starting culture after inoculation is finished, and the temperature of the strain is not yet constant to 35 ℃. At this time, the growth curve fluctuates and is disordered. Indicating that the pressure, temperature, etc. in the bottle are in the early preparation stage. Usually, this period is 0 to 30 minutes in the initial stage of the culture.
And the bc stage is a stable plateau stage, the RGB three curves are relatively stable, the temperature in the stage is detected, and the temperature is found to reach the constant culture temperature of 35 ℃. At this time, the pressure in the bottle was stable and the temperature was constant.
The cd stage is a bacterial fission stage, the RGB three curves begin to break balance, the R \ G line is upward, and the B line is downward. The pressure at this time was measured at the time of the test and started to increase.
The de stage is a rapid growth stage, the R line is rapidly upward, the G line is next to the G line, the B line is downward, and the three values of R \ G \ B are enlarged.
The ef stage is a saturation stage, and the three values of R \ G \ B are kept in parallel at corresponding intervals and unchanged, which indicates that the bacterial growth in the bottle reaches a saturation state.
Tests prove that after the bacteria reach the cd stage, the corresponding biochemical sensor arranged in the blood culture bottle changes color irreversibly. Therefore, the yang determination timing is set to be in the cd segment.
To provide a reliable interpretation, the ab segment shown in FIG. 3 was cut away and the improvement curve is shown in FIG. 4.
As shown in fig. 4, starting at point K, the B value, which had been previously greater than the R value, starts to be less than the R value. And setting a K point as a blood culture positive result demarcation point. R-B =0 may be obtained at this time; from the experimental results, it was found that over time, once the K point was broken, the R value began to become progressively larger than the B value, and the difference became larger and larger. Meanwhile, the color of the biochemical sensor of the blood culture bottle is gradually and obviously changed when the human eyes observe the biochemical sensor.
Therefore, according to the RGB three-color value change, the positive judgment method comprises the following steps:
1) time conditions are as follows: the culture time is T more than 30 minutes
2) Trigger time: r-value = B-value; namely: R-B =0
3) And (3) judging a positive result: R-B > 2; after 5 minutes, calculating that R-B is more than 2;
then the result is judged to be positive.
For a few bacteria with little gas production in the growth process, the color change range of the biochemical sensor at the bottom of the blood culture bottle is limited, even the intersection of the R value and the B value can not occur, and the judgment condition is not met.
Therefore, in practical application, false positive or false negative misjudgment often occurs in the interpretation method in the prior art, and meanwhile, the judgment period is long, which brings trouble to clinical use.
Disclosure of Invention
The invention mainly aims to provide a colorimetric blood culture interpretation method and aims to solve the technical problem of improving the efficiency of a blood culture judgment method.
The invention provides a colorimetric blood culture interpretation method, which comprises the following steps:
judging whether the bacterial culture duration reaches a first preset value;
if so, acquiring RGB values of the bottom of the blood culture bottle, and judging whether the conditions for converting the RGB values into HSV values are met, wherein H represents a hue value, S represents a saturation value, and V represents a brightness value;
if yes, converting the RGB value into an HSV value;
acquiring a first change critical point and a second change critical point corresponding to the H value, wherein the first change critical point is a critical point at which the H value is changed from a constant value to a constant value, and the second change critical point is a critical point at which the H value is changed from a constant value to a constant value;
acquiring H values corresponding to the first change critical point and the second change critical point, and judging whether the difference value of the H values corresponding to the first change critical point and the second change critical point is greater than a second preset value;
if yes, judging that the current moment is a positive judgment moment, and judging whether the S value is more than or equal to the H value;
if so, the blood culture result is judged to be a positive result.
Preferably, the step of determining whether the condition for converting the RGB value into the HSV value is met includes:
judging whether the R value is smaller than the B value or not according to a preset time interval;
if the R value is smaller than the B value in two consecutive results, converting the RGB value into the HSV value.
The invention also provides a colorimetric blood culture interpretation device, comprising:
the first judgment module is used for judging whether the bacteria culture duration reaches a first preset value;
the second judgment module is used for acquiring the RGB value of the bottom of the blood culture bottle and judging whether the condition of converting the RGB value into the HSV value is met or not if the RGB value is the same as the HSV value, wherein H represents a hue value, S represents a saturation value, and V represents a brightness value;
the conversion module is used for converting the RGB numerical value into the HSV numerical value if the RGB numerical value is the HSV numerical value;
the acquisition module is used for acquiring a first change critical point and a second change critical point corresponding to the H value, wherein the first change critical point is a critical point of the H value from constant to changing, and the second change critical point is a critical point of the H value from changing to constant;
the third judgment module is used for acquiring H values corresponding to the first change critical point and the second change critical point and judging whether the difference value of the H values corresponding to the first change critical point and the second change critical point is larger than a second preset value or not;
the fourth judgment module is used for judging whether the current moment is the sun judgment moment and judging whether the S value is larger than or equal to the H value if the current moment is the sun judgment moment;
and the execution module is used for judging that the blood culture result is a positive result if the blood culture result is positive.
Preferably, the second determination module includes:
the judgment submodule is used for judging whether the R value is smaller than the B value or not according to a preset time interval;
and the execution submodule is used for converting the RGB value into the HSV value if the R value is smaller than the B value in two consecutive results.
The invention has the beneficial effects that: the growth of bacteria can enable the liquid state in the blood culture bottle to become more turbid, so that the change of the reflection degree of a biochemical sensor arranged in the bottom of the blood culture bottle can be brought, the blood culture result is detected according to the reflection degree, the misjudgment (false negative result and false positive result) caused by the RGB method when the bacteria are too few can be avoided, the result can be obtained by one-time judgment, the continuous twice judgment is not needed like the traditional technology, and the detection time is shortened. In conclusion, the method and the device not only improve the detection accuracy of the blood culture result, but also shorten the detection time, thereby improving the detection efficiency!
Drawings
FIG. 1 is a schematic diagram of HSV values for a first embodiment of a bacterial growth curve corresponding to a colorimetric blood culture interpretation method of the present invention;
FIG. 2 is a graph of a first RGB value of a prior art bacterial growth curve;
FIG. 3 is a graph of a second RGB value of a prior art bacterial growth curve;
FIG. 4 is a graph of a third RGB value of a prior art bacterial growth curve;
FIG. 5 is a schematic structural view of a first embodiment of a colorimetric blood culture reading device according to the present invention.
Description of reference numerals:
1. a first judgment module; 2. A second judgment module; 3. A conversion module; 4. An acquisition module;
5. a third judgment module; 6. A fourth judging module; 7. And executing the module.
The implementation, functional features and advantages of the objects of the present invention will be further explained with reference to the accompanying drawings.
Detailed Description
It should be understood that the specific embodiments described herein are merely illustrative of the invention and do not limit the invention.
Referring to fig. 1, the present invention provides a colorimetric blood culture interpretation method, including:
s1: judging whether the bacteria culture duration reaches a first preset value;
s2: if so, acquiring an RGB value of the bottom of the blood culture bottle, and judging whether a condition for converting the RGB value into an HSV value is met, wherein H represents a hue value, S represents a saturation value, and V represents a brightness value;
s3: if yes, converting the RGB numerical value into HSV numerical value;
s4: acquiring a first change critical point and a second change critical point corresponding to the H value, wherein the first change critical point is a critical point at which the H value is changed from a constant value to a constant value, and the second change critical point is a critical point at which the H value is changed from a constant value to a constant value;
s5: acquiring H values corresponding to a first change critical point and a second change critical point, and judging whether the difference value of the H values corresponding to the first change critical point and the second change critical point is greater than a second preset value;
s6: if yes, judging that the current moment is a positive judgment moment, and judging whether the S value is more than or equal to the H value;
s7: if so, the blood culture result is judged to be a positive result.
In the embodiment of the present invention, it is determined whether the bacteria culture time reaches a first preset value (e.g., greater than 30 minutes). If so, acquiring RGB values of the bottom of the blood culture bottle, and judging whether the conditions for converting the RGB values into HSV values are met. When the conditions are met, the RGB values of the blood culture are converted into HSV values. And acquiring the H values corresponding to the first change critical point G and the second change critical point K1, and determining whether the difference between the H value at the point G and the H value at the point K1 is greater than a second preset value (for example, the second preset value is 10). If yes, the current time is judged as the positive judgment time, whether the S value is larger than or equal to the H value is judged, and if yes, the blood culture result is judged as a positive result. The growth of bacteria can enable the liquid state in the blood culture bottle to become more turbid, so that the change of the reflection degree of a biochemical sensor arranged in the bottom of the blood culture bottle can be brought, the blood culture result is detected according to the reflection degree, the misjudgment (false negative result and false positive result) caused by the RGB method when the bacteria are too few can be avoided, the result can be obtained by one-time judgment, the continuous twice judgment is not needed like the traditional technology, and the detection time is shortened. In conclusion, the method not only improves the detection accuracy of the blood culture result, but also shortens the detection time, thereby improving the detection efficiency!
Further, the step S2 of determining whether the condition for converting the RGB value into the HSV value is met includes:
s21: judging whether the R value is smaller than the B value or not according to a preset time interval;
s22: and if the R value is smaller than the H value in two consecutive times, converting the RGB value into an HSV value.
In the embodiment of the invention, whether the R value is smaller than the B value or not is judged according to the time interval (such as the interval of 5 minutes), and if the R value is smaller than the B value in two consecutive times, the RGB value is converted into the HSV value.
Referring to fig. 5, the present invention provides a colorimetric blood culture interpretation device including:
the first judgment module 1 is used for judging whether the bacteria culture duration reaches a first preset value;
a second judging module 2, configured to, if yes, obtain an RGB value of the bottom of the blood culture bottle, and judge whether a condition for converting the RGB value into an HSV value is achieved, where H denotes a hue value, S denotes a saturation value, and V denotes a brightness value;
the conversion module 3 is used for converting the RGB numerical value into the HSV numerical value if the RGB numerical value is positive;
the obtaining module 4 is configured to obtain a first change critical point and a second change critical point corresponding to the H value, where the first change critical point is a critical point at which the H value changes from a constant value to a constant value, and the second change critical point is a critical point at which the H value changes from a constant value to a constant value;
the third judging module 5 is configured to obtain H values corresponding to the first change critical point and the second change critical point, and judge whether a difference between the H values corresponding to the first change critical point and the second change critical point is greater than a second preset value;
a fourth judging module 6, configured to, if yes, judge that the current time is a sun judgment time, and judge whether the S value is greater than or equal to the H value;
and the execution module 7 is used for judging that the blood culture result is a positive result if the result is positive.
In the embodiment of the present invention, it is determined whether the bacteria culture time reaches a first preset value (e.g., greater than 30 minutes). If so, acquiring RGB values of the bottom of the blood culture bottle, and judging whether the conditions for converting the RGB values into HSV values are met. When the conditions are met, the RGB values of the blood culture are converted into HSV values. And acquiring H values corresponding to the first change critical point G and the second change critical point K1, and judging whether the difference value between the H value of the point G and the H value of the point K1 is greater than a second preset value (for example, the second preset value is 10). If yes, the current time is judged as the positive judgment time, whether the S value is larger than or equal to the H value is judged, and if yes, the blood culture result is judged as a positive result. The growth of bacteria can enable the liquid in the blood culture bottle to become more turbid, so that the reflectivity of a biochemical sensor arranged in the bottom of the blood culture bottle can be changed, the blood culture result is detected according to the reflectivity, the misjudgment (false negative result and false positive result) caused by an RGB method when the bacteria are too few can be avoided, the result can be obtained by one-time judgment, the continuous two-time judgment is not needed like the traditional technology, and the detection time is shortened. In conclusion, the method and the device not only improve the detection accuracy of the blood culture result, but also shorten the detection time, thereby improving the detection efficiency!
Further, the second determination module includes:
the judgment submodule is used for judging whether the R value is smaller than the B value or not according to a preset time interval;
and the execution submodule is used for converting the RGB value into the HSV value if the R value is smaller than the B value as a result of two consecutive times.
In the embodiment of the invention, whether the R value is smaller than the B value or not is judged according to the time interval (such as the interval of 5 minutes), and if the R value is smaller than the B value in two consecutive times, the RGB value is converted into the HSV value.
The above description is only a preferred embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, which are made by using the contents of the present specification and the accompanying drawings, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.
Claims (4)
1. A colorimetric blood culture interpretation method is characterized by comprising the following steps:
judging whether the bacteria culture duration reaches a first preset value;
if so, acquiring RGB numerical values of the bottom of the blood culture bottle, and judging whether the conditions for converting the RGB numerical values into HSV numerical values are met, wherein H represents a hue value, S represents a saturation value, and V represents a brightness value;
if so, converting the RGB value into the HSV value;
acquiring a first change critical point and a second change critical point corresponding to the H value, wherein the first change critical point is a critical point of the H value from constant to changing, and the second change critical point is a critical point of the H value from changing to constant;
acquiring H values corresponding to the first change critical point and the second change critical point, and judging whether the difference value of the H values corresponding to the first change critical point and the second change critical point is greater than a second preset value;
if yes, judging that the current moment is a positive judgment moment, and judging whether the S value is more than or equal to the H value;
if so, the blood culture result is judged to be a positive result.
2. The colorimetric blood culture interpretation method according to claim 1, wherein the step of judging whether the condition for converting the RGB value into the HSV value is achieved comprises:
judging whether the R value is smaller than the B value or not according to a preset time interval;
and if the R value is smaller than the B value in two consecutive times, converting the RGB value into the HSV value.
3. A colorimetric blood culture interpretation device comprising:
the first judgment module is used for judging whether the bacteria culture duration reaches a first preset value;
the second judgment module is used for acquiring the RGB value of the bottom of the blood culture bottle and judging whether the condition of converting the RGB value into the HSV value is met or not if the RGB value is the bottom of the blood culture bottle, wherein H represents a hue value, S represents a saturation value, and V represents a brightness value;
the conversion module is used for converting the RGB numerical value into the HSV numerical value if the RGB numerical value is the same as the HSV numerical value;
the acquisition module is used for acquiring a first change critical point and a second change critical point corresponding to the H value, wherein the first change critical point is a critical point of the H value from constant to changing, and the second change critical point is a critical point of the H value from changing to constant;
the third judging module is used for acquiring H values corresponding to the first change critical point and the second change critical point and judging whether the difference value of the H values corresponding to the first change critical point and the second change critical point is larger than a second preset value or not;
the fourth judgment module is used for judging whether the current moment is the sun judgment moment and judging whether the S value is larger than or equal to the H value if the current moment is the sun judgment moment;
and the execution module is used for judging that the blood culture result is a positive result if the blood culture result is positive.
4. The colorimetric blood culture interpretation device according to claim 3, wherein the second judgment module comprises:
the judgment submodule is used for judging whether the R value is smaller than the B value or not according to a preset time interval;
and the execution submodule is used for converting the RGB value into the HSV value if the R value is smaller than the B value as a result of two consecutive times.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110310310.3A CN113073039B (en) | 2021-03-23 | 2021-03-23 | Colorimetric blood culture interpretation method and device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110310310.3A CN113073039B (en) | 2021-03-23 | 2021-03-23 | Colorimetric blood culture interpretation method and device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113073039A CN113073039A (en) | 2021-07-06 |
| CN113073039B true CN113073039B (en) | 2022-09-06 |
Family
ID=76613707
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110310310.3A Active CN113073039B (en) | 2021-03-23 | 2021-03-23 | Colorimetric blood culture interpretation method and device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113073039B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114317672A (en) * | 2021-12-30 | 2022-04-12 | 苏州新实医疗科技有限公司 | Blood culture bottle culture detection state display method and blood culture instrument |
Citations (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0380949A2 (en) * | 1989-02-02 | 1990-08-08 | Berthold Koch | Reference cell for evaluating the turbidity of liquids |
| US5817475A (en) * | 1996-11-15 | 1998-10-06 | Giles Scientific, Inc. | Automatic microbiological testing apparatus and method |
| CN102016062A (en) * | 2008-02-19 | 2011-04-13 | 贝克顿·迪金森公司 | Systems and methods for identifying a culture as positive for microorganisms with high confidence |
| JP2012002532A (en) * | 2010-06-14 | 2012-01-05 | Nippon Telegr & Teleph Corp <Ntt> | Method, device, and program for diagnosing deterioration |
| EP2713334A1 (en) * | 2011-06-28 | 2014-04-02 | Rakuten, Inc. | Product image processing apparatus, product image processing method, information storing medium, and program |
| CN106769893A (en) * | 2016-11-22 | 2017-05-31 | 西安建筑科技大学 | A kind of characterizing method of the sludge microbe COMMUNITY CHARACTERISTICS based on color space |
| CN107850556A (en) * | 2015-07-22 | 2018-03-27 | 矢崎总业株式会社 | Check device and inspection method |
| CN108279238A (en) * | 2018-01-30 | 2018-07-13 | 深圳春沐源控股有限公司 | A kind of fruit maturity judgment method and device |
| KR101876151B1 (en) * | 2017-12-13 | 2018-08-09 | (주)에스티엠 | Sample analyte measurement method |
| CN109324039A (en) * | 2017-07-31 | 2019-02-12 | 爱威科技股份有限公司 | Test strips reaction density detection method, device, storage medium and computer equipment |
| CN109704234A (en) * | 2019-02-25 | 2019-05-03 | 齐鲁工业大学 | A kind of identification of medical waste bucket judges grasping system and method |
| CN208857258U (en) * | 2018-06-23 | 2019-05-14 | 郑州安图生物工程股份有限公司 | Tissue culture plate interpretation device |
| WO2019164814A1 (en) * | 2018-02-20 | 2019-08-29 | Purdue Research Foundation | System and method of detecting contaminants |
| CN112241697A (en) * | 2020-10-10 | 2021-01-19 | 上海欧菲智能车联科技有限公司 | Corner color determination method and device, terminal device and readable storage medium |
| CN113409277A (en) * | 2021-06-22 | 2021-09-17 | 陈战士 | Metering detection method and device for agricultural product production |
| CN214334987U (en) * | 2020-12-31 | 2021-10-01 | 重庆民朗科技有限公司 | Blood culture detection module |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200063197A1 (en) * | 2017-05-15 | 2020-02-27 | Arizona Board Of Regents On Behalf Of Arizona State University | Quantitative detection and analysis of target dna with colorimetric rt-qlamp |
| CN211122550U (en) * | 2019-12-08 | 2020-07-28 | 中国科学院新疆理化技术研究所 | Hand-held explosive and drug colorimetric analyzer |
-
2021
- 2021-03-23 CN CN202110310310.3A patent/CN113073039B/en active Active
Patent Citations (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0380949A2 (en) * | 1989-02-02 | 1990-08-08 | Berthold Koch | Reference cell for evaluating the turbidity of liquids |
| US5817475A (en) * | 1996-11-15 | 1998-10-06 | Giles Scientific, Inc. | Automatic microbiological testing apparatus and method |
| CN102016062A (en) * | 2008-02-19 | 2011-04-13 | 贝克顿·迪金森公司 | Systems and methods for identifying a culture as positive for microorganisms with high confidence |
| JP2012002532A (en) * | 2010-06-14 | 2012-01-05 | Nippon Telegr & Teleph Corp <Ntt> | Method, device, and program for diagnosing deterioration |
| EP2713334A1 (en) * | 2011-06-28 | 2014-04-02 | Rakuten, Inc. | Product image processing apparatus, product image processing method, information storing medium, and program |
| CN107850556A (en) * | 2015-07-22 | 2018-03-27 | 矢崎总业株式会社 | Check device and inspection method |
| CN106769893A (en) * | 2016-11-22 | 2017-05-31 | 西安建筑科技大学 | A kind of characterizing method of the sludge microbe COMMUNITY CHARACTERISTICS based on color space |
| CN109324039A (en) * | 2017-07-31 | 2019-02-12 | 爱威科技股份有限公司 | Test strips reaction density detection method, device, storage medium and computer equipment |
| KR101876151B1 (en) * | 2017-12-13 | 2018-08-09 | (주)에스티엠 | Sample analyte measurement method |
| CN108279238A (en) * | 2018-01-30 | 2018-07-13 | 深圳春沐源控股有限公司 | A kind of fruit maturity judgment method and device |
| WO2019164814A1 (en) * | 2018-02-20 | 2019-08-29 | Purdue Research Foundation | System and method of detecting contaminants |
| CN208857258U (en) * | 2018-06-23 | 2019-05-14 | 郑州安图生物工程股份有限公司 | Tissue culture plate interpretation device |
| CN109704234A (en) * | 2019-02-25 | 2019-05-03 | 齐鲁工业大学 | A kind of identification of medical waste bucket judges grasping system and method |
| CN112241697A (en) * | 2020-10-10 | 2021-01-19 | 上海欧菲智能车联科技有限公司 | Corner color determination method and device, terminal device and readable storage medium |
| CN214334987U (en) * | 2020-12-31 | 2021-10-01 | 重庆民朗科技有限公司 | Blood culture detection module |
| CN113409277A (en) * | 2021-06-22 | 2021-09-17 | 陈战士 | Metering detection method and device for agricultural product production |
Non-Patent Citations (5)
| Title |
|---|
| CNPt-Direct与Blue-Carba化学比色法检测阳性血培养瓶中产碳青霉烯酶肠杆菌科细菌应用价值研究;刘亚萌 等;《临床军医杂志》;20191115;第47卷(第11期);第1207-1215页 * |
| Generalized filtering operations for hue images;Park, H等;《OPTICAL ENGINEERING》;20010131;第40卷(第1期);第100-107页 * |
| Implementation of RGB to HSV Color Space Conversion with Xilinx System Generator;Long Wen等;《Advanced Materials Research》;20130923;第816卷;第527-534页 * |
| 不同浓度条件下液溶胶丁达尔现象的研究;李万军 等;《化学教育》;20160402;第37卷(第7期);第77-81页 * |
| 基于FPGA的RGB和HSV色空间转换算法实现;袁奋杰;《电子器件》;20100820;第33卷(第4期);第493-497页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN113073039A (en) | 2021-07-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN113073039B (en) | Colorimetric blood culture interpretation method and device | |
| CN104977296B (en) | A kind of detection method and device of novel alcoholic strength | |
| CN201069389Y (en) | Photoelectric color recognition testing instrument | |
| CN102610996A (en) | Method and device for rapidly calibrating luminous power | |
| CN109324039A (en) | Test strips reaction density detection method, device, storage medium and computer equipment | |
| CN103743425B (en) | The detection method of gauge pointer dynamic response capability | |
| CN113850154A (en) | Inverter IGBT (insulated Gate Bipolar transistor) micro fault feature extraction method based on multi-modal data | |
| CN115343345A (en) | High-precision detection method of glucolase biosensor based on adaptive Kalman filtering algorithm | |
| CN109490393B (en) | Method and system for analyzing quality of yeast material by extraction method of characteristic values of physicochemical indexes in yeast for making hard liquor | |
| CN109115847B (en) | Electrochemical fingerprint spectrum detection method for protein powder | |
| CN105675168B (en) | Automatic numbering device and method for temperature sensors | |
| Haddad et al. | A feature extraction algorithm for multi-peak signals in electronic noses | |
| CN206256041U (en) | Brewing fermentation monitor control system in a kind of tank | |
| CN205486181U (en) | A automatic verification system that is used for pointer gauge head and simple and easy digital gauge outfit | |
| November et al. | Evaluation of on-line viable biomass measurements during fermentations of Candida utilis | |
| CN110887943B (en) | Method for improving response speed of oxygen concentration sensor | |
| CN112863135A (en) | Experimental process prompting and early warning system of experimental assistant robot | |
| CN205750589U (en) | A kind of based on monolithic processor controlled intelligent temperature controller | |
| WO1997014781A1 (en) | Method of making an alcoholic beverage by fermentation, and fermentation test kit for use in the method | |
| CN209276541U (en) | A kind of dry ferment device for detecting activity | |
| CN215727635U (en) | Rapid inspection device for automatic blood culture instrument | |
| CN1818654A (en) | Fast trace inspection of tissue acetylcholinesterase | |
| CN217059934U (en) | Water pollution detects check-up equipment with DNA biosensor | |
| CN107748021A (en) | A kind of temperature sensor dynamic testing method based on FPGA | |
| CN111537409B (en) | High-precision erythrocyte sedimentation temperature compensation measuring method and device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |