CN113040288A - Poultry feed additive and application thereof - Google Patents
Poultry feed additive and application thereof Download PDFInfo
- Publication number
- CN113040288A CN113040288A CN201911377241.7A CN201911377241A CN113040288A CN 113040288 A CN113040288 A CN 113040288A CN 201911377241 A CN201911377241 A CN 201911377241A CN 113040288 A CN113040288 A CN 113040288A
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- parts
- weight
- poultry
- feed
- feed additive
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- 244000144977 poultry Species 0.000 title claims abstract description 72
- 239000003674 animal food additive Substances 0.000 title claims abstract description 50
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 71
- 229920000057 Mannan Polymers 0.000 claims abstract description 43
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims abstract description 29
- 235000019752 Wheat Middilings Nutrition 0.000 claims abstract description 29
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 claims abstract description 29
- 229910052901 montmorillonite Inorganic materials 0.000 claims abstract description 29
- 239000011669 selenium Substances 0.000 claims abstract description 29
- 229910052711 selenium Inorganic materials 0.000 claims abstract description 29
- 235000011649 selenium Nutrition 0.000 claims abstract description 29
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims abstract description 18
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims abstract description 9
- 235000017557 sodium bicarbonate Nutrition 0.000 claims abstract description 9
- 235000019764 Soybean Meal Nutrition 0.000 claims description 36
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 36
- 239000011707 mineral Substances 0.000 claims description 36
- 239000004455 soybean meal Substances 0.000 claims description 36
- 229940088594 vitamin Drugs 0.000 claims description 31
- 239000011782 vitamin Substances 0.000 claims description 31
- 239000001763 2-hydroxyethyl(trimethyl)azanium Substances 0.000 claims description 28
- 235000019743 Choline chloride Nutrition 0.000 claims description 28
- 229960003178 choline chloride Drugs 0.000 claims description 28
- SGMZJAMFUVOLNK-UHFFFAOYSA-M choline chloride Chemical compound [Cl-].C[N+](C)(C)CCO SGMZJAMFUVOLNK-UHFFFAOYSA-M 0.000 claims description 28
- 235000012054 meals Nutrition 0.000 claims description 28
- 235000019779 Rapeseed Meal Nutrition 0.000 claims description 26
- 240000008042 Zea mays Species 0.000 claims description 26
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 26
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 26
- 235000005822 corn Nutrition 0.000 claims description 26
- 235000012343 cottonseed oil Nutrition 0.000 claims description 26
- 239000000843 powder Substances 0.000 claims description 26
- 239000004456 rapeseed meal Substances 0.000 claims description 26
- 150000003839 salts Chemical class 0.000 claims description 26
- 235000012424 soybean oil Nutrition 0.000 claims description 26
- 239000003549 soybean oil Substances 0.000 claims description 26
- 239000004575 stone Substances 0.000 claims description 26
- 239000000126 substance Substances 0.000 claims description 26
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims description 22
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 22
- 239000004472 Lysine Substances 0.000 claims description 22
- 229930182817 methionine Natural products 0.000 claims description 22
- 210000000056 organ Anatomy 0.000 claims description 17
- 150000001413 amino acids Chemical class 0.000 claims description 8
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 6
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims description 6
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 6
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 6
- 235000010755 mineral Nutrition 0.000 claims description 6
- 102000004169 proteins and genes Human genes 0.000 claims description 6
- 108090000623 proteins and genes Proteins 0.000 claims description 6
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 4
- 230000036039 immunity Effects 0.000 claims description 4
- 239000003921 oil Substances 0.000 claims description 4
- 235000019198 oils Nutrition 0.000 claims description 4
- 230000004083 survival effect Effects 0.000 claims description 4
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 3
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 3
- 229930003427 Vitamin E Natural products 0.000 claims description 3
- 229960002685 biotin Drugs 0.000 claims description 3
- 235000020958 biotin Nutrition 0.000 claims description 3
- 239000011616 biotin Substances 0.000 claims description 3
- 229960000304 folic acid Drugs 0.000 claims description 3
- 235000019152 folic acid Nutrition 0.000 claims description 3
- 239000011724 folic acid Substances 0.000 claims description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 3
- 239000011664 nicotinic acid Substances 0.000 claims description 3
- 229940055726 pantothenic acid Drugs 0.000 claims description 3
- 235000019161 pantothenic acid Nutrition 0.000 claims description 3
- 239000011713 pantothenic acid Substances 0.000 claims description 3
- 239000011715 vitamin B12 Substances 0.000 claims description 3
- 239000011716 vitamin B2 Substances 0.000 claims description 3
- 239000011726 vitamin B6 Substances 0.000 claims description 3
- 239000011647 vitamin D3 Substances 0.000 claims description 3
- 235000019165 vitamin E Nutrition 0.000 claims description 3
- 239000011709 vitamin E Substances 0.000 claims description 3
- 229940046009 vitamin E Drugs 0.000 claims description 3
- 239000011652 vitamin K3 Substances 0.000 claims description 3
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 2
- 235000017060 Arachis glabrata Nutrition 0.000 claims description 2
- 244000105624 Arachis hypogaea Species 0.000 claims description 2
- 235000010777 Arachis hypogaea Nutrition 0.000 claims description 2
- 235000018262 Arachis monticola Nutrition 0.000 claims description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 2
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 claims description 2
- 240000007594 Oryza sativa Species 0.000 claims description 2
- 235000007164 Oryza sativa Nutrition 0.000 claims description 2
- 241000209140 Triticum Species 0.000 claims description 2
- 235000021307 Triticum Nutrition 0.000 claims description 2
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 2
- 229910052802 copper Inorganic materials 0.000 claims description 2
- 239000010949 copper Substances 0.000 claims description 2
- 239000003651 drinking water Substances 0.000 claims description 2
- 235000020188 drinking water Nutrition 0.000 claims description 2
- 235000020232 peanut Nutrition 0.000 claims description 2
- 230000001105 regulatory effect Effects 0.000 claims description 2
- 235000009566 rice Nutrition 0.000 claims description 2
- 235000019155 vitamin A Nutrition 0.000 claims description 2
- 239000011719 vitamin A Substances 0.000 claims description 2
- 239000011718 vitamin C Substances 0.000 claims description 2
- 229940045997 vitamin a Drugs 0.000 claims description 2
- 239000011701 zinc Substances 0.000 claims description 2
- 229910052725 zinc Inorganic materials 0.000 claims description 2
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims 3
- 235000019700 dicalcium phosphate Nutrition 0.000 claims 3
- 235000013594 poultry meat Nutrition 0.000 abstract description 51
- 238000004091 panning Methods 0.000 abstract description 7
- 230000008901 benefit Effects 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- 235000013305 food Nutrition 0.000 abstract description 4
- 241000287828 Gallus gallus Species 0.000 description 59
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 23
- 239000011575 calcium Substances 0.000 description 23
- 229910052791 calcium Inorganic materials 0.000 description 23
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 20
- 230000000052 comparative effect Effects 0.000 description 19
- 235000013330 chicken meat Nutrition 0.000 description 10
- 229960001231 choline Drugs 0.000 description 10
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 10
- 230000000694 effects Effects 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- 208000010359 Newcastle Disease Diseases 0.000 description 7
- 239000003242 anti bacterial agent Substances 0.000 description 5
- 206010059866 Drug resistance Diseases 0.000 description 4
- 229940088710 antibiotic agent Drugs 0.000 description 4
- 210000001669 bursa of fabricius Anatomy 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 230000003053 immunization Effects 0.000 description 4
- 238000002649 immunization Methods 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 3
- 241000411851 herbal medicine Species 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 210000003323 beak Anatomy 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 210000003746 feather Anatomy 0.000 description 2
- 210000002865 immune cell Anatomy 0.000 description 2
- 230000028993 immune response Effects 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 230000017448 oviposition Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 229960005486 vaccine Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- 210000001325 yolk sac Anatomy 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 108010001857 Cell Surface Receptors Proteins 0.000 description 1
- 108060003951 Immunoglobulin Proteins 0.000 description 1
- 206010062016 Immunosuppression Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 229930003448 Vitamin K Natural products 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000003640 drug residue Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 235000021050 feed intake Nutrition 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000035931 haemagglutination Effects 0.000 description 1
- 230000004727 humoral immunity Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 230000001506 immunosuppresive effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 102000006240 membrane receptors Human genes 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001932 seasonal effect Effects 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/28—Silicates, e.g. perlites, zeolites or bentonites
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
- A23K40/10—Shaping or working-up of animal feeding-stuffs by agglomeration; by granulation, e.g. making powders
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Health & Medical Sciences (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Birds (AREA)
- Fodder In General (AREA)
Abstract
The invention provides a poultry feed additive and application thereof, wherein the poultry feed additive contains yeast mannan, montmorillonite, yeast selenium, sodium bicarbonate and wheat middling. The poultry feed additive provided by the invention can improve the poultry antibody level and reduce the death and panning, thereby improving the poultry production benefit and ensuring the quality safety of poultry meat and egg food.
Description
Technical Field
The invention relates to a feed additive, in particular to a poultry feed additive.
Background
The antibody is an immune globulin generated by the immune response of an organism, and when poultry grow and develop in various physiological periods such as yolk sac digestion metabolism in a brooding period, moulting in an egg laying period and the like, and stress such as beak breaking, group transfer, season changing and the like can influence the reduction of the antibody level of the poultry organism to cause various diseases. In the actual culture process, the treatment by antibiotics can cause the animals to generate drug resistance and immunosuppression to destroy the immune system of the organism, further reduce the antibody level of the animals, increase the death and culling rate and reduce the production benefit.
At present, except antibiotics, other antibacterial agents in the market are mainly derived from Chinese herbal medicines and chemically synthesized polysaccharides, and due to the fact that the extraction process is complex, the use cost is high, the product components are not clear, and the product quality difference is large. The yeast mannan is a high-efficiency biological responder with strong activity, no toxic or side effect and no drug resistance to antibiotics, can act on an immune cell surface receptor to activate an immune related signal conduction path, promote immune cells to release downstream signal molecules and induce an organism to generate nonspecific and specific immune response reaction, has the functions of resisting tumors, enhancing the immunity of the organism, resisting bacteria and viruses and the like, and is widely used in the medicine and food industries.
The use of chemically synthesized antibiotics has the problems of drug resistance, drug residue and the like, and some synthetic raw materials have toxic action; the function and the content of components for enhancing immunity in the Chinese herbal medicine additive are not clear, and the consistency of the using effect of the feed produced in different batches is difficult to ensure.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a poultry feed additive. The feed additive can promote the development of poultry immune organs and improve the poultry antibody level.
In a first aspect, the invention provides a poultry feed additive, which comprises yeast mannan, montmorillonite, yeast selenium, sodium bicarbonate and wheat middling.
The poultry feed additive comprises, by weight, 0.005-0.3 part of yeast mannan, 0.05-0.5 part of montmorillonite, 0.005-0.3 part of yeast selenium, 0.01-0.5 part of sodium bicarbonate and 2-8 parts of wheat middling.
Preferably, the poultry feed additive comprises 0.01-0.1 part of yeast mannan, 0.1-0.3 part of montmorillonite, 0.01-0.1 part of yeast selenium, 0.01-0.05 part of sodium bicarbonate and 2-8 parts of wheat middling in parts by weight.
Preferably, the poultry feed additive comprises 0.03-0.08 part of yeast mannan, 0.2-0.3 part of montmorillonite, 0.03-0.08 part of yeast selenium and 0.02-0.04 part of sodium bicarbonate by weight part
And 5-7 parts of wheat middling.
Preferably, the poultry feed additive also contains a multi-vitamin multi-mineral premix, and the multi-vitamin multi-mineral premix contains vitamin A and vitamin B2Vitamin B6Vitamin B12Vitamin C, vitamin D3Nicotinic acid, pantothenic acid, folic acid, biotin, vitamin E, vitamin K3Copper element, zinc element, iron element and manganese element.
Preferably, the mass percentage of the multi-vitamin and multi-mineral premix in the poultry feed additive is 1-13%.
Preferably, the content of the multi-vitamin multi-mineral premix in the poultry feed additive is 0.1 to 0.7 part by weight.
The multi-dimensional multi-mineral premix provided by the invention is obtained by commercial purchase or self-made.
Preferably, each kilogram of the multi-vitamin and multi-mineral premix contains vitamin A4000-8000 KIU and vitamin B25000-15000mg of vitamin B65000-15000mg of vitamin B1250-100mg, vitamin C200000-300000 mg, vitamin D31000-2000KIU, 50000-150000mg nicotinic acid, 600000mg pantothenic acid, 600000mg folic acid, 500-2000mg biotin, 1000-3000mg vitamin E, 40000 mg vitamin K, 60000mg vitamin K36000mg of 4000-.
Preferably, the poultry feed additive also contains amino acid substances, and preferably, the amino acid substances are selected from one or the combination of more than two of methionine and lysine.
Preferably, the mass percentage of the amino acid substances in the poultry feed additive is 0.1-36%.
Preferably, the content of the amino acid substances in the poultry feed additive is 0.01-3 parts by weight.
In a second aspect, the invention provides the use of the poultry feed additive in poultry feed or poultry drinking water.
In a third aspect, the invention provides a feed comprising said poultry feed additive.
Preferably, the feed consists of the poultry feed additive and a basic ration, and the mass ratio of the poultry feed additive to the basic ration is 1-10: 90-99.
Preferably, the feed also contains an energy supply substance, preferably, the energy supply substance is selected from one or the combination of more than two of corn, rice and wheat, and preferably, the energy supply substance is 40-70 parts by weight.
Preferably, the feed also contains protein substances, preferably, the protein substances are selected from one or more of soybean meal, rapeseed meal, cottonseed meal and peanut meal, and preferably, the protein substances are 0.1-50 parts by weight.
Preferably, the feed also contains mineral substances, preferably, the mineral substances are selected from one or more of salt, calcium hydrophosphate and stone powder, and preferably, the content of the mineral substances is 0.01-15 parts by weight.
Preferably, the feed also contains oil and fat substances, preferably, the oil and fat substances are selected from soybean oil, and preferably, the content of the oil and fat substances is 1-10 parts by weight.
Preferably, the feed also contains choline chloride, and the content of the choline chloride is 0.01-1 part by weight.
Preferably, the feed also comprises 40-70 parts of corn, 10-50 parts of soybean meal, 0.1-10 parts of cottonseed meal, 0.1-10 parts of rapeseed meal, 1-10 parts of soybean oil, 0.1-5 parts of calcium hydrophosphate, 0.1-5 parts of stone powder, 0.01-5 parts of salt and 0.01-1 part of choline chloride by weight.
Preferably, the feed also comprises 50-60 parts of corn, 20-30 parts of soybean meal, 1-5 parts of cottonseed meal, 0.5-4 parts of rapeseed meal, 2-5 parts of soybean oil, 1-2 parts of calcium hydrophosphate, 1-1.5 parts of stone powder, 0.1-1 part of salt and 0.05-0.5 part of choline chloride by weight.
The poultry feed additive provided by the invention or the application of the feed provided by the invention is any one of the following 1) or 2):
1) the application in regulating the immune organs of poultry; 2) the application in improving the immunity of poultry bodies; 3) application in improving survival rate of poultry.
The poultry feed additive provided by the invention can improve the poultry antibody level reduction caused by stress of various feeding stages, such as yolk sac digestion metabolism in brooding period, growth period, moulting in egg laying period and the like, and various external environment changes, such as beak breaking, colony transfer, seasonal temperature difference change, feed raw material pollution and the like.
The poultry feed additive provided by the invention has the advantages of no residue and no drug resistance, and is beneficial to the safety of poultry meat and egg food; compared with Chinese herbal medicine additives, the yeast mannan has definite components, can be industrially produced, and has stable product quality.
The poultry feed additive provided by the invention can promote the development of poultry immune organs, thereby improving the poultry antibody level, reducing death and panning, further improving the poultry production benefit and ensuring the poultry meat and egg food safety.
Detailed Description
The present invention will be described in further detail with reference to specific examples in order to provide those skilled in the art with a better understanding of the invention. It should be understood by those skilled in the art that this should not be construed as limiting the scope of the claims of the present invention. It should be noted that the reagent or the apparatus of the present invention can be obtained by commercially available methods without specific mention.
The content of mannan in the yeast mannan is more than or equal to 40 percent.
Specific sources of the raw materials and equipment used in the present invention are listed in table 1 below.
Table 1 materials and equipment used in the examples
Example 1
1000kg of broiler feed, wherein the feed comprises the following components in parts by mass: 1-21 days old: 59 parts of corn, 28 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 2.3 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.4 parts of stone powder, 0.3 part of salt, 0.1 part of choline chloride, 0.14 part of 99% methionine, 0.36 part of 98.5% lysine, 0.4 part of multi-mineral multi-vitamin premix, 5.07 parts of wheat middling, 0.01 part of sodium bicarbonate, 0.2 part of montmorillonite, 0.01 part of yeast mannan and 0.01 part of yeast selenium. Age 22-42 days: 60 parts of corn, 24 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 3.1 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.32 parts of stone powder, 0.3 part of salt, 0.12 part of 99% methionine, 0.26 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 7.37 parts of wheat middling, 0.01 part of sodium bicarbonate, 0.3 part of montmorillonite, 0.01 part of yeast mannan and 0.01 part of yeast selenium. Wherein the protein content of the soybean meal is more than 40%, and the choline content is more than 60%. The content of the yeast mannan is more than or equal to 40 percent.
Example 2
1000kg of broiler feed, wherein the feed comprises the following components in parts by mass: 1-21 days old: 59 parts of corn, 28 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 2.3 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.4 parts of stone powder, 0.3 part of salt, 0.14 part of 99% methionine, 0.36 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 5.03 parts of wheat middling, 0.02 part of sodium bicarbonate, 0.2 part of montmorillonite, 0.03 part of yeast mannan and 0.02 part of yeast selenium. Age 22-42 days: 60 parts of corn, 24 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 3.1 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.32 parts of stone powder, 0.3 part of salt, 0.12 part of 99% methionine, 0.26 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 7.33 parts of wheat middling, 0.02 part of sodium bicarbonate, 0.3 part of montmorillonite, 0.03 part of yeast mannan and 0.02 part of yeast selenium. Wherein the protein content of the soybean meal is more than 40%, and the choline content is more than 60%. The content of the yeast mannan is more than or equal to 40 percent.
Example 3
1000kg of broiler feed, wherein the feed comprises the following components in parts by mass: 1-21 days old: 59 parts of corn, 28 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 2.3 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.4 parts of stone powder, 0.3 part of salt, 0.14 part of 99% methionine, 0.36 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 4.99 parts of wheat middling, 0.03 part of sodium bicarbonate, 0.2 part of montmorillonite, 0.05 part of yeast mannan and 0.03 part of yeast selenium. Age 22-42 days: 60 parts of corn, 24 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 3.1 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.32 parts of stone powder, 0.3 part of salt, 0.12 part of 99% methionine, 0.26 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 7.29 parts of wheat middling, 0.03 part of sodium bicarbonate, 0.3 part of montmorillonite, 0.05 part of yeast mannan and 0.03 part of yeast selenium. Wherein the protein content of the soybean meal is more than 40%, and the choline content is more than 60%. The content of the yeast mannan is more than or equal to 40 percent.
Example 4
1000kg of broiler feed, wherein the feed comprises the following components in parts by mass: 1-21 days old: 59 parts of corn, 28 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 2.3 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.4 parts of stone powder, 0.3 part of salt, 0.14 part of 99% methionine, 0.36 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 4.93 parts of wheat middling, 0.04 part of sodium bicarbonate, 0.2 part of montmorillonite, 0.08 part of yeast mannan and 0.05 part of yeast selenium. Age 22-42 days: 60 parts of corn, 24 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 3.1 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.32 parts of stone powder, 0.3 part of salt, 0.12 part of 99% methionine, 0.26 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 7.23 parts of wheat middling, 0.04 part of sodium bicarbonate, 0.3 part of montmorillonite, 0.08 part of yeast mannan and 0.05 part of yeast selenium. Wherein the protein content of the soybean meal is more than 40%, and the choline content is more than 60%. The content of the yeast mannan is more than or equal to 40 percent.
Example 5
1000kg of broiler feed, wherein the feed comprises the following components in parts by mass: 1-21 days old: 59 parts of corn, 28 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 2.3 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.4 parts of stone powder, 0.3 part of salt, 0.14 part of 99% methionine, 0.36 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 4.87 parts of wheat middling, 0.05 part of sodium bicarbonate, 0.2 part of montmorillonite, 0.1 part of yeast mannan and 0.08 part of yeast selenium. Age 22-42 days: 60 parts of corn, 24 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 3.1 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.32 parts of stone powder, 0.3 part of salt, 0.12 part of 99% methionine, 0.26 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 7.17 parts of wheat middling, 0.05 part of sodium bicarbonate, 0.3 part of montmorillonite, 0.1 part of yeast mannan and 0.08 part of yeast selenium. Wherein the protein content of the soybean meal is more than 40%, and the choline content is more than 60%. The content of the yeast mannan is more than or equal to 40 percent.
Comparative example 1
1000kg of broiler feed, wherein the feed comprises the following components in parts by mass: 1-21 days old: 59 parts of corn, 28 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 2.3 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.4 parts of stone powder, 0.3 part of salt, 0.14 part of 99% methionine, 0.36 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 5.3 parts of wheat middling, 0 part of sodium bicarbonate, 0 part of montmorillonite, 0 part of yeast mannan and 0 part of yeast selenium. Age 22-42 days: 60 parts of corn, 24 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 3.1 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.32 parts of stone powder, 0.3 part of salt, 0.12 part of 99% methionine, 0.26 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 7.7 parts of wheat middling, 0 part of sodium bicarbonate, 0 part of montmorillonite, 0 part of yeast mannan and 0 part of yeast selenium. Wherein the protein content of the soybean meal is more than 40%, and the choline content is more than 60%. The content of the yeast mannan is more than or equal to 40 percent.
Comparative example 2
1000kg of broiler feed, wherein the feed comprises the following components in parts by mass: 1-21 days old: 59 parts of corn, 28 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 2.3 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.4 parts of stone powder, 0.3 part of salt, 0.14 part of 99% methionine, 0.36 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 1.8 parts of wheat middling, 1.2 parts of sodium bicarbonate, 1.3 parts of montmorillonite, 0.5 part of yeast mannan and 0.5 part of yeast selenium. Age 22-42 days: 60 parts of corn, 24 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 3.1 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.32 parts of stone powder, 0.3 part of salt, 0.12 part of 99% methionine, 0.26 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 1.8 parts of wheat middling, 1.2 parts of sodium bicarbonate, 3.7 parts of montmorillonite, 0.5 part of yeast mannan and 0.5 part of yeast selenium. Wherein the protein content of the soybean meal is more than 40%, and the choline content is more than 60%. The content of the yeast mannan is more than or equal to 40 percent.
Comparative example 3
1000kg of broiler feed, wherein the feed comprises the following components in parts by mass: 1-21 days old: 59 parts of corn, 28 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 2.3 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.4 parts of stone powder, 0.3 part of salt, 0.14 part of 99% methionine, 0.36 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 5.01 parts of wheat middling, 0.04 part of sodium bicarbonate, 0.2 part of montmorillonite, 0 part of yeast mannan and 0.05 part of yeast selenium. Age 22-42 days: 60 parts of corn, 24 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 3.1 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.32 parts of stone powder, 0.3 part of salt, 0.12 part of 99% methionine, 0.26 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 7.31 parts of wheat middling, 0.04 part of sodium bicarbonate, 0.3 part of montmorillonite, 0 part of yeast mannan and 0.05 part of yeast selenium. Wherein the protein content of the soybean meal is more than 40%, and the choline content is more than 60%. The content of the yeast mannan is more than or equal to 40 percent.
Comparative example 4
1000kg of broiler feed, wherein the feed comprises the following components in parts by mass: 1-21 days old: 59 parts of corn, 28 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 2.3 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.4 parts of stone powder, 0.3 part of salt, 0.14 part of 99% methionine, 0.36 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 0 part of wheat middling, 0 part of sodium bicarbonate, 0 part of montmorillonite, 3.3 parts of yeast mannan and 2 parts of yeast selenium. Age 22-42 days: 60 parts of corn, 24 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 3.1 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.32 parts of stone powder, 0.3 part of salt, 0.12 part of 99% methionine, 0.26 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 0 part of wheat middling, 0 part of sodium bicarbonate, 0 part of montmorillonite, 4.7 parts of yeast mannan and 3 parts of yeast selenium. Wherein the protein content of the soybean meal is more than 40%, and the choline content is more than 60%. The content of the yeast mannan is more than or equal to 40 percent.
Comparative example 5
1000kg of broiler feed, wherein the feed comprises the following components in parts by mass: 1-21 days old: 59 parts of corn, 28 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 2.3 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.4 parts of stone powder, 0.3 part of salt, 0.14 part of 99% methionine, 0.36 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 4.98 parts of wheat middling, 0.04 part of sodium bicarbonate, 0.2 part of montmorillonite, 0.08 part of yeast mannan and 0 part of yeast selenium. Age 22-42 days: 60 parts of corn, 24 parts of soybean meal, 1 part of cottonseed meal, 0.5 part of rapeseed meal, 3.1 parts of soybean oil, 1.2 parts of calcium hydrophosphate, 1.32 parts of stone powder, 0.3 part of salt, 0.12 part of 99% methionine, 0.26 part of 98.5% lysine, 0.1 part of choline chloride, 0.4 part of multi-mineral multi-vitamin premix, 7.28 parts of wheat middling, 0.04 part of sodium bicarbonate, 0.3 part of montmorillonite, 0.08 part of yeast mannan and 0 part of yeast selenium. Wherein the protein content of the soybean meal is more than 40%, and the choline content is more than 60%. The content of the yeast mannan is more than or equal to 40 percent.
Influence of various groups of feeds on growth indexes of broilers
1 examples validation test: 4000 feathers of white feather broilers of 1 day old are selected in the test, and the test chickens are randomly divided into 10 groups (example 1, example 2, example 3, example 4, example 5, comparative example 1, comparative example 2, comparative example 3, comparative example 4 and comparative example 5), wherein each group has 4 repetitions and each repetition has 100 chickens. The test feed adopts the feed formulas in the corresponding examples or comparative examples of each group, the feed is firstly crushed, is gradually expanded and mixed and then is granulated, the feed is crushed in the early stage, and the crushing is not needed in the later stage. The test broiler chickens are raised in a plane scattered mode, fed and drunk freely, and normal broiler chicken raising management is referred to.
2 index of production Performance
Feed-meat ratio (F/G): and calculating the feed-meat ratio of each stage and the feed-meat ratio of the whole stage on the basis of the broiler chickens living at a certain stage. And recording the weight of dead eliminated chickens, and correcting the feed consumption of the dead eliminated chickens when calculating the feed-meat ratio.
Feed conversion ratio (average daily feed intake per chicken/average daily gain per chicken) (correction)
The death and culling rate: dead and culled chickens (well documented) account for the proportion of the whole population.
3 immunoassay index
Immune organ index: the moderate virulence vaccine of the bursa of Fabricius is inoculated at a dropping mouth which is 1 time of 14 days old, one chicken with approximate average weight is picked in each group before immunization (14 days old), 7 days after immunization (21 days old), 14 days after immunization (28 days old) and 21 days after immunization (35 days old), the bursa of Fabricius of chicken immune organs are collected and weighed by an electronic balance, and the index of the bursa of Fabricius is determined. The immune organ index is calculated by referring to the method of snow plum and the like (2009), and the formula is as follows: organ index is organ fresh weight (g)/live weight (kg).
The humoral immunity index is as follows: the new combined vaccine is inoculated by dropping 1 time of eyes and nose at 7 days of age, 1 chicken is randomly extracted from each column at 7 days (14 days of age), 14 days (21 days of age) and 21 days (28 days of age) at 7 am to 8 am, the blood is collected from the inferior pterygoid vein, the serum is separated, and the antibody titer of the serum Newcastle disease in the blood is detected by a hemagglutination inhibition test.
4 results and analysis
1) Influence on growth performance of broiler chickens
When the broilers in each group were fed for 21d and 42d, the weights were weighed and the average weight of the broilers in each group was calculated, and the results are shown in table 2.
TABLE 2 influence of different feeds on feed conversion ratio of broilers
As can be seen from Table 2, the weight of the broilers fed with the feeds provided in examples 1-5 was increased as compared with the weight of the broilers fed with the feeds provided in comparative examples 1-5, and particularly, the weight of the broilers fed with the feed provided in example 5 was 695.28g at 21 days and 2.53kg at 42 days, which was significantly different from the weight of the broilers fed with the feeds provided in comparative examples 1-5.
Meanwhile, as can be seen from table 2, the feed ratio of the broiler chickens fed with the feeds provided in examples 1 to 5 was lower than that of the broiler chickens fed with the feeds provided in comparative examples 1 to 5, and particularly, the feed ratio of the broiler chickens fed with the feed provided in example 4 was 1.66 at 1 to 21d and 2.08 at 22 to 42 d.
The data show that the poultry feed additive provided by the invention can better promote broilers to absorb nutrient substances and improve the utilization rate of the feed.
The results of the mortality and culling rate of the broilers in different growth stages of the broilers in each group are shown in table 3.
TABLE 3 influence of different feeds on mortality and culling rate of broilers
As shown in table 3, in terms of dead panning, the dead panning rate of the broilers fed with the feeds provided in examples 1 to 5 of the present invention is significantly lower than that of the broilers fed with the feeds provided in comparative examples 1 to 5, especially the dead panning rate of the broilers fed with the feed provided in example 4 is the lowest, compared with the feed provided in comparative example 1, the dead panning rates of the broilers fed with the feed provided in example 4 at 21-day-old and 42-day-old are respectively reduced by 31.58% and 61.11%, so that the dead panning rate can be significantly reduced, which indicates that the poultry feed additive provided by the present invention has an effect of significantly improving the survival rate of poultry.
2) Influence on immune organs of broiler chickens
The test results of the influence of the feeds of each group on the indexes of immune organs of the broilers are shown in table 4. The results show that the immune organ indexes of the broilers fed with the feeds provided by the examples 1-5 of the invention are higher than those of the broilers fed with the feeds provided by the comparative examples, and particularly the feed provided by the example 4 can obviously improve the immune organ indexes of the broilers, which shows that the poultry feed additive provided by the invention can promote the development of bursa of Fabricius of immune organs of the broilers.
TABLE 4 influence on immune organ indices of broilers
3) Effect of different feeds on Newcastle disease antibody levels in broiler chickens
The results of the tests on the effect of the feed provided in examples 1 to 5 and comparative examples 1 to 5 on Newcastle disease immune antibodies in broiler chickens are shown in Table 5.
TABLE 5 Effect on Newcastle disease immune antibody titers in broiler chickens
As shown in table 5, the newcastle disease immune antibody titer of the broilers fed with the feeds provided in examples 1 to 5 of the present invention is significantly higher than that of the broilers fed with the feeds provided in comparative examples 1 to 5, and particularly, the newcastle disease immune antibody titer of the broilers fed with the feed provided in example 4 reaches 7.30 at 14 days of age, 8.12 at 21 days of age, and 7.50 at 28 days of age, and at the same time, as can be seen from the dispersion of the antibody titer, the antibody titer generated in example 4 is relatively uniform and can maintain a relatively stable antibody level in the next two weeks, which indicates that the poultry feed additive provided by the present invention can improve and stabilize the newcastle disease antibody level of the broilers.
The experimental results prove that the poultry feed additive provided by the invention can obviously improve the survival rate of poultry, immune organ index and immune antibody level, can obviously reduce the death and culling rate, promotes the development of immune organs of broilers, improves the poultry antibody titer, and has the effects of improving the poultry antibody level and production benefit.
Claims (15)
1. The poultry feed additive is characterized by comprising yeast mannan, montmorillonite, yeast selenium, sodium bicarbonate and wheat middling.
2. The poultry feed additive as claimed in claim 1, wherein the poultry feed additive comprises yeast mannan 0.005-0.3 part, montmorillonite 0.05-0.5 part, yeast selenium 0.005-0.3 part, sodium bicarbonate 0.01-0.5 part and wheat middling 2-8 parts;
preferably, the poultry feed additive comprises 0.01-0.1 part of yeast mannan, 0.1-0.3 part of montmorillonite, 0.01-0.1 part of yeast selenium, 0.01-0.05 part of sodium bicarbonate and 2-8 parts of wheat middling in parts by weight;
more preferably, the poultry feed additive comprises 0.03-0.08 part of yeast mannan, 0.2-0.3 part of montmorillonite, 0.03-0.08 part of yeast selenium, 0.02-0.04 part of sodium bicarbonate and 5-7 parts of wheat middling in parts by weight.
3. The poultry feed additive according to claim 1 or 2, wherein the poultry feed additive further comprises a multi-vitamin multi-mineral premix, wherein the multi-vitamin multi-mineral premix comprises vitamin A and vitamin B2Vitamin B6Vitamin B12Vitamin C, vitamin D3Nicotinic acid, pantothenic acid, folic acid, biotin, vitamin E, vitamin K3Copper element, zinc element, iron element and manganese element;
preferably, the mass percentage of the multi-vitamin and multi-mineral premix in the poultry feed additive is 1-13%;
preferably, the content of the multi-vitamin multi-mineral premix in the poultry feed additive is 0.1 to 0.7 part by weight.
4. The poultry feed additive according to any one of claims 1 to 3, wherein the poultry feed additive further comprises amino acids, preferably the amino acids are selected from one or a combination of more than two of methionine and lysine;
preferably, the mass percentage of the amino acid substances in the poultry feed additive is 0.1-36%;
preferably, the content of the amino acid substances in the poultry feed additive is 0.01-3 parts by weight.
5. Use of a poultry feed additive according to any one of claims 1-4 in poultry feed or poultry drinking water.
6. A feed comprising the poultry feed additive of any one of claims 1 to 4.
7. The feed of claim 6, wherein the feed consists of the poultry feed additive and a basal ration in a mass ratio of the poultry feed additive to the basal ration of 1-10: 90-99.
8. The feed according to claim 6 or 7, wherein the feed further comprises an energy supplying substance, preferably the energy supplying substance is selected from one or a combination of more than two of corn, rice and wheat, preferably the energy supplying substance is 40-70 parts by weight.
9. The feed according to any one of claims 6 to 8, wherein the feed further comprises a protein substance, preferably the protein substance is selected from one or a combination of more than two of soybean meal, rapeseed meal, cottonseed meal and peanut meal, and preferably the protein substance is 0.1 to 50 parts by weight.
10. The feed according to any one of claims 6 to 9, wherein the feed further comprises a mineral, preferably the mineral is selected from one or a combination of more than two of salt, calcium hydrogen phosphate and stone powder, preferably the mineral is contained in an amount of 0.01 to 15 parts by weight.
11. The feed according to any one of claims 6 to 10, further comprising a fat and oil substance, preferably selected from the group consisting of soybean oil, preferably in an amount of 1 to 10 parts by weight.
12. The feed according to any one of claims 6 to 11, wherein the feed further comprises choline chloride, preferably the choline chloride is present in an amount of 0.01 to 1 part by weight.
13. The feed according to any one of claims 6 to 12, wherein the feed further comprises 40 to 70 parts by weight of corn, 10 to 50 parts by weight of soybean meal, 0.1 to 10 parts by weight of cottonseed meal, 0.1 to 10 parts by weight of rapeseed meal, 1 to 10 parts by weight of soybean oil, 0.1 to 5 parts by weight of calcium hydrogen phosphate, 0.1 to 5 parts by weight of stone powder, 0.01 to 5 parts by weight of salt, and 0.01 to 1 part by weight of choline chloride.
14. The feed according to any one of claims 6 to 13, wherein the feed further comprises 50 to 60 parts by weight of corn, 20 to 30 parts by weight of soybean meal, 1 to 5 parts by weight of cottonseed meal, 0.5 to 4 parts by weight of rapeseed meal, 2 to 5 parts by weight of soybean oil, 1 to 2 parts by weight of calcium hydrogen phosphate, 1 to 1.5 parts by weight of stone powder, 0.1 to 1 part by weight of salt, and 0.05 to 0.5 part by weight of choline chloride.
15. Use of the poultry feed additive according to any one of claims 1-4 or the feed according to any one of claims 6-14 as any one of the following 1) or 2):
1) the application in regulating the immune organs of poultry; 2) the application in improving the immunity of poultry bodies; 3) application in improving survival rate of poultry.
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