CN113034641B - Sparse angle CT reconstruction method based on wavelet multi-scale convolution feature coding - Google Patents

Sparse angle CT reconstruction method based on wavelet multi-scale convolution feature coding Download PDF

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CN113034641B
CN113034641B CN202110331020.7A CN202110331020A CN113034641B CN 113034641 B CN113034641 B CN 113034641B CN 202110331020 A CN202110331020 A CN 202110331020A CN 113034641 B CN113034641 B CN 113034641B
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刘进
亢艳芹
强俊
王勇
夏振宇
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Abstract

本发明公开了一种基于小波多尺度卷积特征编码的稀疏角度CT重建方法,属于计算机断层成像技术领域。本发明先对高质量的CT样本图像进行小波变换获得高频系数图,再对高频系数图进行多尺度卷积特征学习,构建多尺度滤波器字典;然后引入构建的多尺度滤波器字典,建立小波多尺度卷积特征编码约束的稀疏角度CT重建模型;对重建模型进行变量分解,分为卷积特征学习更新目标函数和重建图像更新目标函数;最后通过交替迭代的策略更新重建图像及多尺度滤波器字典,获得最终重建图像。本发明可有效减缓稀疏角度CT重建中的条状伪影及细节丢失情况,并提高重建图像对比度,促进稀疏角度CT扫描在临床诊断与治疗领域中的使用。

Figure 202110331020

The invention discloses a sparse angle CT reconstruction method based on wavelet multi-scale convolution feature coding, which belongs to the technical field of computed tomography. The method first performs wavelet transformation on high-quality CT sample images to obtain a high-frequency coefficient map, then performs multi-scale convolution feature learning on the high-frequency coefficient map to construct a multi-scale filter dictionary; and then introduces the constructed multi-scale filter dictionary, A sparse angle CT reconstruction model with wavelet multi-scale convolution feature coding constraints is established; the reconstruction model is decomposed into variables, which are divided into convolution feature learning update objective function and reconstructed image update objective function; A dictionary of scale filters to obtain the final reconstructed image. The invention can effectively reduce the stripe artifacts and the loss of details in the sparse angle CT reconstruction, improve the contrast of the reconstructed image, and promote the use of the sparse angle CT scan in the field of clinical diagnosis and treatment.

Figure 202110331020

Description

一种基于小波多尺度卷积特征编码的稀疏角度CT重建方法A Sparse Angle CT Reconstruction Method Based on Wavelet Multiscale Convolutional Feature Coding

技术领域technical field

本发明涉及计算机断层成像技术领域,更具体地说,涉及一种基于小波多尺度卷积特征编码的稀疏角度CT重建方法。The invention relates to the technical field of computerized tomography, and more specifically, to a sparse-angle CT reconstruction method based on wavelet multi-scale convolution feature coding.

背景技术Background technique

计算机断层成像(Computed Tomography,CT)是利用物体成分的X射线衰减差异,通过重建算法呈现准确无误的结构信息的影像技术,可实现无创检测。CT成像具有空间分辨率高、扫描成本低、时间短等一系列优势,在临床中与磁共振成像、超声波成像和正电子发射断层成像等技术互补,可以为疾病筛查、诊断和治疗提供了影像基础,是目前各级医院不可缺少的医疗设备之一。然而,过多的X射线照射能损伤组织细胞,增加潜在疾病获得风险。据调查,在一次常规螺旋CT扫描中,检查者可能受到1.5~10mSv的辐射剂量照射,远高于普通胸透检查0.2~0.5mSv的剂量。随着检查次数的增加,辐射还具有累积效应,延长检查者所受的伤害,此外一些特殊人群(如儿童,孕妇,老年人等)所伤害更大。为此,在不影响图像诊断的前提下,尽可能降低X射线剂量。Computed Tomography (CT) is an image technology that uses the X-ray attenuation difference of object components to present accurate structural information through reconstruction algorithms, and can realize non-invasive detection. CT imaging has a series of advantages such as high spatial resolution, low scanning cost, and short time. It is complementary to magnetic resonance imaging, ultrasound imaging, and positron emission tomography in clinical practice, and can provide imaging for disease screening, diagnosis, and treatment. The foundation is one of the indispensable medical equipment in hospitals at all levels. However, excessive X-ray exposure can damage tissue cells, increasing the risk of acquiring underlying diseases. According to the survey, in a conventional spiral CT scan, the examiner may be exposed to a radiation dose of 1.5-10 mSv, which is much higher than the dose of 0.2-0.5 mSv in ordinary chest X-ray examination. As the number of inspections increases, radiation also has a cumulative effect, prolonging the damage suffered by the examiner, and some special groups (such as children, pregnant women, the elderly, etc.) are more injured. Therefore, the X-ray dose should be reduced as much as possible without affecting the image diagnosis.

采用稀疏角度扫描,降低投影数据角度个数,是减少X射线照射的一种有效途径。然而,降低射线的采样会导致采集信号的缺失,进而引起重建图像退化,尤其是会导致组织细节丢失,增加重建图的条状伪影,导致医师在阅片时出现漏诊和误诊的情况。为提高稀疏角度CT成像效果:一方面,从CT图像角度出发,研究人员设计专业的图像复原及处理算法,以抑制伪影,增强图像细节。但不同扫描设备、模式及重建方法下,CT图像的伪影表征差异大,这也导致该方法泛化能力差。另一方面,从CT投影数据角度出发,对原始数据或对数变换后的投影数据进行修复、复原等处理,以提高投影数据的一致性,进而可提高重建效果。但由于投影数据敏感性较高,处理过程中,易出现欠校正、过校正及数据一致性低等情况。此外,改进重建算法也是提高成像效果的一种主要途径,近年来大量的迭代重建算法被提出并取得了优异的成绩,尤其是基于先验信息约束的统计迭代重建算法。但是这类算法面临的主要问题有:超参数多,难以自适应优化;算法复杂度高,需要重复迭代计算;先验信息具有不稳定性,无法获得统一框架下的先验项等,使得迭代重建在临床应用场景下难以充分发挥其价值。虽然“稀疏扫描成像”中仍存有诸多问题,但这些都将是未来CT研究领域的重要指标,也是X射线成像发展的主要方向。Using sparse angle scanning to reduce the number of projection data angles is an effective way to reduce X-ray exposure. However, reducing the sampling of rays will lead to the loss of acquired signals, which in turn will cause the degradation of the reconstructed image, especially the loss of tissue details and increase the streak artifacts of the reconstructed image, which will lead to missed diagnosis and misdiagnosis when doctors read the image. In order to improve the effect of sparse-angle CT imaging: On the one hand, from the perspective of CT images, researchers design professional image restoration and processing algorithms to suppress artifacts and enhance image details. However, under different scanning equipment, modes and reconstruction methods, the artifact representation of CT images varies greatly, which also leads to poor generalization ability of this method. On the other hand, from the perspective of CT projection data, the original data or the projection data after logarithmic transformation are repaired and restored to improve the consistency of the projection data, thereby improving the reconstruction effect. However, due to the high sensitivity of projection data, under-correction, over-correction and low data consistency are prone to occur during processing. In addition, improving the reconstruction algorithm is also a main way to improve the imaging effect. In recent years, a large number of iterative reconstruction algorithms have been proposed and achieved excellent results, especially the statistical iterative reconstruction algorithm based on prior information constraints. However, the main problems faced by this type of algorithm are: there are many hyperparameters, it is difficult to adaptively optimize; the algorithm complexity is high, and repeated iterative calculations are required; Reconstruction is difficult to give full play to its value in clinical application scenarios. Although there are still many problems in "sparse scanning imaging", these will be important indicators in the field of CT research in the future, and also the main direction of X-ray imaging development.

将稀疏特征学习作为先验模型,构成约束项,被广泛应用于稀疏角度CT重建中。稀疏特征学习类方法也展现了优越的性能,极大地推进了稀疏角度CT成像算法的实用化。该类方法主要是通过样本训练构造字典,并利用字典对信号进行稀疏编码,在特征识别、分类和图像复原等领域中受到广泛关注。然而,传统的稀疏特征学习,其先验信息提取能力有限,如何拓展增强其特征学习能力,如何设计多种尺度的特征编码形式,以充分发挥其优势,并更好的服务于低剂量CT成像,是临床CT成像发展的关键问题。Sparse feature learning is used as a priori model to constitute a constraint item, which is widely used in sparse angle CT reconstruction. Sparse feature learning methods also exhibit superior performance, which greatly promotes the practicality of sparse-angle CT imaging algorithms. This type of method mainly constructs a dictionary through sample training, and uses the dictionary to sparsely encode the signal. It has received extensive attention in the fields of feature recognition, classification, and image restoration. However, the traditional sparse feature learning has limited a priori information extraction ability. How to expand and enhance its feature learning ability, how to design multi-scale feature encoding forms, so as to give full play to its advantages and better serve low-dose CT imaging , is a key issue in the development of clinical CT imaging.

公开于该背景技术部分的信息仅仅旨在增加对本发明的总体背景的理解,而不应当被视为承认或以任何形式暗示该信息构成已为本领域一般技术人员所公知的现有技术。The information disclosed in this Background section is only for enhancing the understanding of the general background of the present invention and should not be taken as an acknowledgment or any form of suggestion that the information constitutes the prior art that is already known to those skilled in the art.

发明内容Contents of the invention

1.发明要解决的技术问题1. The technical problem to be solved by the invention

本发明的目的在于克服现有技术中稀疏角度CT重建方法存在的图像质量不高、伪影残留多、组织细节丢失、对比度低等问题,拟提供一种基于小波多尺度卷积特征编码的稀疏角度CT重建方法,称之为小波多尺度卷积特征编码约束重建(Wavelet domain Multi-Scale Convolutional sparse coding constrained Reconstruction,简称WMCR)。该方法是在不改变现有的CT硬件成本条件下,通过多尺度上的卷积特征学习,以提高特征信息感知、编码及解码能力,获得丰富的先验知识,为稀疏角度CT优质重建服务。本发明通过抑制由扫描角度缺失引起的图像伪影和细节丢失现象,来提高稀疏角度CT重建图像质量,并最终为患者降低额外辐射,增加诊疗收益。The purpose of the present invention is to overcome the problems of low image quality, residual artifacts, loss of tissue details, and low contrast existing in the sparse angle CT reconstruction method in the prior art, and to provide a sparse angle CT reconstruction method based on wavelet multi-scale convolution feature coding The angle CT reconstruction method is called Wavelet domain Multi-Scale Convolutional sparse coding constrained Reconstruction (WMCR for short). This method is to improve feature information perception, encoding and decoding capabilities through multi-scale convolutional feature learning without changing the cost of existing CT hardware, obtain rich prior knowledge, and serve for high-quality reconstruction of sparse-angle CT . The present invention improves image quality of sparse-angle CT reconstruction by suppressing image artifacts and loss of details caused by missing scanning angles, and ultimately reduces extra radiation for patients and increases diagnosis and treatment benefits.

2.技术方案2. Technical solution

为达到上述目的,本发明提供的技术方案为:In order to achieve the above object, the technical scheme provided by the invention is:

本发明的一种基于小波多尺度卷积特征编码的稀疏角度CT重建方法,包括以下步骤:A kind of sparse angle CT reconstruction method based on wavelet multi-scale convolution feature coding of the present invention comprises the following steps:

步骤1、获取初始多尺度滤波器字典原子;Step 1. Obtain the initial multi-scale filter dictionary atom;

对给定的高质量CT样本图像xs进行小波变换,获得高频和低频小波系数,其中高频系数部分表示为

Figure GDA0003856912530000021
Figure GDA0003856912530000022
Figure GDA0003856912530000023
分别为水平、垂直和对角三个方向的子带信号;对F0进行多尺度卷积特征学习,获取初始的多尺度滤波器字典原子
Figure GDA0003856912530000024
Perform wavelet transformation on a given high-quality CT sample image x s to obtain high-frequency and low-frequency wavelet coefficients, where the high-frequency coefficients are expressed as
Figure GDA0003856912530000021
Figure GDA0003856912530000022
and
Figure GDA0003856912530000023
are the sub-band signals in the horizontal, vertical and diagonal directions respectively; perform multi-scale convolution feature learning on F 0 to obtain the initial multi-scale filter dictionary atoms
Figure GDA0003856912530000024

学习模型表示为:The learning model is expressed as:

Figure GDA0003856912530000025
Figure GDA0003856912530000025

其中*为卷积算子,K为卷积核尺度数,N为单个尺度下卷积核个数,

Figure GDA0003856912530000026
为对应原子的特征图,β为正则化参数;Where * is the convolution operator, K is the number of convolution kernel scales, and N is the number of convolution kernels at a single scale,
Figure GDA0003856912530000026
is the feature map of the corresponding atom, and β is the regularization parameter;

步骤2、构建小波多尺度卷积特征编码约束的稀疏角度CT重建模型;Step 2. Construct a sparse-angle CT reconstruction model constrained by wavelet multi-scale convolution feature coding;

步骤3、重建模型分解:对重建模型进行固定变量分解,获得卷积特征学习更新目标函数和待重建图像更新目标函数;Step 3. Reconstruction model decomposition: Decompose the reconstruction model with fixed variables to obtain the convolution feature learning update objective function and the image update objective function to be reconstructed;

步骤4、交替的方式求解卷积特征学习更新目标函数和待重建图像更新目标函数获得最终的重建结果图。Step 4. Alternately solve the convolution feature learning update objective function and the image to be reconstructed update objective function to obtain the final reconstruction result map.

更进一步地,步骤2中构建的重建模型表示为:Further, the reconstructed model constructed in step 2 is expressed as:

Figure GDA0003856912530000031
Figure GDA0003856912530000031

其中*为卷积算子,K为卷积核尺度数,N为单个尺度下卷积核个数,A为CT系统的投影矩阵,x为待重建图像,p为稀疏投影数据,W为小波变换高频系数提取算子,λ和β为正则化参数,dn,k为多尺度滤波器字典原子,Mn,k为对应的特征图。Where * is the convolution operator, K is the number of convolution kernel scales, N is the number of convolution kernels at a single scale, A is the projection matrix of the CT system, x is the image to be reconstructed, p is the sparse projection data, and W is the wavelet Transform the high-frequency coefficient extraction operator, λ and β are the regularization parameters, d n, k are the multi-scale filter dictionary atoms, and M n, k are the corresponding feature maps.

更进一步地,步骤3中分解获得的卷积特征学习更新目标函数和待重建图像更新目标函数,分别表示为:Furthermore, the convolutional feature learning update objective function obtained by decomposing in step 3 and the update objective function of the image to be reconstructed are respectively expressed as:

Figure GDA0003856912530000032
Figure GDA0003856912530000032

Figure GDA0003856912530000033
Figure GDA0003856912530000033

其中*为卷积算子,K为卷积核尺度数,N为单个尺度下卷积核个数,A为CT系统的投影矩阵,x为待重建图像,p为稀疏投影数据,W为小波变换高频系数提取算子,λ和β为正则化参数,xt为第t(0≤t)次更新后的待重建图像,

Figure GDA0003856912530000034
为第t次更新后的多尺度滤波器字典原子,
Figure GDA0003856912530000035
为第t次更新后对应原子的特征图。Where * is the convolution operator, K is the number of convolution kernel scales, N is the number of convolution kernels at a single scale, A is the projection matrix of the CT system, x is the image to be reconstructed, p is the sparse projection data, and W is the wavelet Transform the high-frequency coefficient extraction operator, λ and β are regularization parameters, x t is the image to be reconstructed after the tth (0≤t) update,
Figure GDA0003856912530000034
is the multi-scale filter dictionary atom after the tth update,
Figure GDA0003856912530000035
is the feature map of the corresponding atom after the tth update.

更进一步地,步骤1中小波变换采用1层的二维平稳小波变换,选用Haar小波基。Furthermore, in step 1, the wavelet transform adopts a layer 2 two-dimensional stationary wavelet transform, and the Haar wavelet base is selected.

更进一步地,步骤1中多尺度滤波器参数为:卷积核尺度数范围为2≤K≤5,单个尺度下卷积核个数取值范围为32≤N≤64,卷积核大小可选范围为6×6×3至14×14×3。Furthermore, the parameters of the multi-scale filter in step 1 are: the range of convolution kernel scales is 2≤K≤5, the value range of the number of convolution kernels at a single scale is 32≤N≤64, and the size of the convolution kernel can be The selection range is from 6×6×3 to 14×14×3.

更进一步地,步骤1中学习模型式(1)采用交替方向乘子算法求解,获取初始多尺度滤波器字典原子。Furthermore, in step 1, the learning model formula (1) is solved using the alternating direction multiplier algorithm to obtain the initial multi-scale filter dictionary atoms.

更进一步地,步骤2中小波变换高频系数提取算子W的操作步骤为:首先对图像进行1层的二维平稳小波变换,选用Haar小波基;然后选取高频系数部分的水平、垂直和对角三个方向的子带信号;最后对这三个方向的子带信号按照第三维度顺序叠加组合。Furthermore, the operation steps of the wavelet transform high-frequency coefficient extraction operator W in step 2 are as follows: first, perform a 1-layer two-dimensional stationary wavelet transform on the image, and select the Haar wavelet base; then select the horizontal, vertical and The sub-band signals in three diagonal directions; finally, the sub-band signals in these three directions are superimposed and combined according to the order of the third dimension.

更进一步地,步骤3中当t=0时为初始值,初始多尺度滤波器字典原子由步骤1获得,初始待重建图像x0由斜坡滤波器的滤波反投影算法重建获得。Furthermore, in step 3, when t=0 is the initial value, the initial multi-scale filter dictionary atom is obtained in step 1, and the initial image x 0 to be reconstructed is reconstructed by the filter back projection algorithm of the slope filter.

更进一步地,步骤4中卷积特征学习更新目标函数式(3)采用交替方向乘子算法求解,待重建图像更新目标函数式(4)采用抛物面替代算法求解。Furthermore, in step 4, the convolutional feature learning update objective function (3) is solved by the alternating direction multiplier algorithm, and the image update objective function (4) to be reconstructed is solved by the paraboloid substitution algorithm.

更进一步地,步骤4中当迭代前后待重建图像满足RMSE(xt+1-xt)≤30时停止,输出最终的重建结果图,其中RMSE(·)为均方误差计算算子。Furthermore, in step 4, stop when the image to be reconstructed before and after iteration satisfies RMSE(x t+1 -x t )≤30, and output the final reconstruction result map, where RMSE(·) is the mean square error calculation operator.

3.有益效果3. Beneficial effect

采用本发明提供的技术方案,与现有技术相比,具有如下有益效果:Compared with the prior art, the technical solution provided by the invention has the following beneficial effects:

本发明的一种基于小波多尺度卷积特征编码的稀疏角度CT重建方法,首先,对高质量的CT样本图像进行小波变换获得高频系数图,对高频系数图进行多尺度卷积特征学习,构建多尺度滤波器字典;然后,以构建的多尺度滤波器字典为初始值,建立小波域高频系数卷积特征编码约束的重建模型;接下来,对重建模型进行变量分解,分为重建图像更新和多尺度滤波器字典更新;最后,通过交替迭代的策略更新重建图像及多尺度滤波器字典,获得最终重建图像。通过将小波域多尺度卷积特征编码先验引入重建中,可有效的改善了现有的重建方法在稀疏扫描角度重建时出现的条状伪影和细节丢失问题。实验结果验证了在多种稀疏角度扫描数据下,本发明方法(WMCR)与传统的小波域卷积稀疏编码重建方法(Wavelet domain Convolutional Sparse Coding,简称WCSC)相比,可够有效的抑制重建图像中由投影角度缺失导致的条状伪影及细节丢失问题,重建图像具有较好的视觉效果与对比度。本发明方法有望为国内医院影像科室和CT制造商提供先进实用的稀疏角度重建框架,为患者降低额外辐射,增加诊疗收益,具有较高的应用和推广前景。A sparse-angle CT reconstruction method based on wavelet multi-scale convolution feature coding of the present invention, first, perform wavelet transformation on high-quality CT sample images to obtain high-frequency coefficient maps, and perform multi-scale convolution feature learning on high-frequency coefficient maps , to construct a multi-scale filter dictionary; then, with the constructed multi-scale filter dictionary as the initial value, a reconstruction model with the convolution feature coding constraints of high-frequency coefficients in the wavelet domain is established; next, the variable decomposition of the reconstruction model is divided into reconstruction Image update and multi-scale filter dictionary update; finally, the reconstructed image and the multi-scale filter dictionary are updated through an alternate iterative strategy to obtain the final reconstructed image. By introducing the wavelet-domain multi-scale convolutional feature coding prior into the reconstruction, the existing reconstruction methods can effectively improve the problems of strip artifacts and loss of details in the reconstruction of sparse scanning angles. The experimental results have verified that the method of the present invention (WMCR) can effectively suppress the reconstructed image compared with the traditional wavelet domain convolutional sparse coding reconstruction method (WCSC) under the scan data of various sparse angles. The reconstructed image has better visual effect and contrast due to the strip artifacts and loss of details caused by the lack of projection angle. The method of the present invention is expected to provide an advanced and practical sparse angle reconstruction framework for domestic hospital imaging departments and CT manufacturers, reduce additional radiation for patients, increase diagnosis and treatment benefits, and has high application and promotion prospects.

附图说明Description of drawings

图1为本发明中基于小波多尺度卷积特征编码的稀疏角度CT重建方法的流程示意图;Fig. 1 is the schematic flow chart of the sparse angle CT reconstruction method based on wavelet multi-scale convolution feature coding in the present invention;

图2为实施例中腹部180个扫描角度投影数据的重建图(a:参考图;b:FBP重建图;c:WCSC重建图像;d:WMCR重建图像);Fig. 2 is the reconstructed image of projection data of 180 scanning angles of the abdomen in the embodiment (a: reference image; b: FBP reconstructed image; c: WCSC reconstructed image; d: WMCR reconstructed image);

图3为实施例中腹部120个扫描角度投影数据的重建图(a:参考图;b:FBP重建图;c:WCSC重建图像;d:WMCR重建图像);Fig. 3 is the reconstructed image of projection data of 120 scan angles of the abdomen in the embodiment (a: reference image; b: FBP reconstructed image; c: WCSC reconstructed image; d: WMCR reconstructed image);

图4为实施例中腹部重建后滤波器字典集合示意图(a:180个角度扫描实验;b:120个角度扫描实验);Fig. 4 is a schematic diagram of filter dictionary set after abdominal reconstruction in the embodiment (a: 180 angle scanning experiments; b: 120 angle scanning experiments);

图5为实施例中胸部180个扫描角度投影数据的重建图(a:参考图;b:FBP重建图;c:WCSC重建图像;d:WMCR重建图像);Fig. 5 is the reconstructed figure of projection data of 180 scan angles of the chest in the embodiment (a: reference figure; b: FBP reconstructed figure; c: WCSC reconstructed image; d: WMCR reconstructed image);

图6为实施例中胸部120个扫描角度投影数据的重建图(a:参考图;b:FBP重建图;c:WCSC重建图像;d:WMCR重建图像);Fig. 6 is the reconstructed figure of projection data of 120 scanning angles of the chest in the embodiment (a: reference figure; b: FBP reconstructed figure; c: WCSC reconstructed image; d: WMCR reconstructed image);

图7为实施例中胸部投影数据的重建图的Profile曲线(a:180个扫描角度;b:120个扫描角度)。Fig. 7 is the Profile curve of the reconstruction image of the chest projection data in the embodiment (a: 180 scanning angles; b: 120 scanning angles).

具体实施方式Detailed ways

为进一步了解本发明的内容,结合附图对本发明作详细描述。In order to further understand the content of the present invention, the present invention will be described in detail in conjunction with the accompanying drawings.

在本发明的描述中,需要说明的是,术语“中心”、“上”、“下”、“左”、“右”、“竖直”、“水平”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本发明的限制。此外,术语“第一”、“第二”、“第三”仅用于描述目的,而不能理解为指示或暗示相对重要性。In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" etc. The indicated orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, or in a specific orientation. construction and operation, therefore, should not be construed as limiting the invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and should not be construed as indicating or implying relative importance.

下面结合实施例对本发明作进一步的描述。The present invention will be further described below in conjunction with embodiment.

实施例1Example 1

本实施例的一种基于小波多尺度卷积特征编码的稀疏角度CT重建方法流程图如图1所示,具体步骤如下:A flow chart of a sparse angle CT reconstruction method based on wavelet multi-scale convolution feature coding in this embodiment is shown in Figure 1, and the specific steps are as follows:

步骤1、获取初始多尺度滤波器字典原子;Step 1. Obtain the initial multi-scale filter dictionary atom;

对给定的高质量CT样本图像xs进行小波变换,可获得高频和低频小波系数,其中高频系数部分可表示为

Figure GDA0003856912530000051
Figure GDA0003856912530000052
Figure GDA0003856912530000053
分别为水平、垂直和对角三个方向的子带信号;对F0进行多尺度卷积特征学习,获取初始的多尺度滤波器字典原子
Figure GDA0003856912530000054
学习模型可表示为:Perform wavelet transform on a given high-quality CT sample image x s to obtain high-frequency and low-frequency wavelet coefficients, where the high-frequency coefficients can be expressed as
Figure GDA0003856912530000051
Figure GDA0003856912530000052
and
Figure GDA0003856912530000053
are the sub-band signals in the horizontal, vertical and diagonal directions respectively; perform multi-scale convolution feature learning on F 0 to obtain the initial multi-scale filter dictionary atoms
Figure GDA0003856912530000054
The learning model can be expressed as:

Figure GDA0003856912530000055
Figure GDA0003856912530000055

其中*为卷积算子,K为卷积核尺度数,N为单个尺度下卷积核个数,

Figure GDA0003856912530000056
为对应原子的特征图,β为正则化参数。Where * is the convolution operator, K is the number of convolution kernel scales, and N is the number of convolution kernels at a single scale,
Figure GDA0003856912530000056
is the feature map of the corresponding atom, and β is the regularization parameter.

具体的,对给定的高质量CT样本图像xs进行1层的二维平稳小波变换,选用Haar小波基。多尺度滤波器参数为:卷积核尺度个数范围为2≤K≤5,单个尺度下卷积核个数取值范围为32≤N≤64,卷积核大小可选范围为6×6×3至14×14×3之间,具体大小依据扫描角度数、计算机存储空间大小、待重建图像质量等因素手动选择。β为正则化参数依据具体数据手动调节。在使用交替方向乘子算法求解式(1)后,得到初始的多尺度滤波器字典原子

Figure GDA0003856912530000061
Specifically, the given high-quality CT sample image x s is subjected to one-layer two-dimensional stationary wavelet transform, and the Haar wavelet base is selected. The multi-scale filter parameters are: the range of the number of convolution kernel scales is 2≤K≤5, the value range of the number of convolution kernels at a single scale is 32≤N≤64, and the optional range of convolution kernel size is 6×6 Between ×3 and 14×14×3, the specific size is manually selected based on factors such as the number of scanning angles, the size of computer storage space, and the quality of the image to be reconstructed. β is a regularization parameter that is manually adjusted according to specific data. After solving Equation (1) using the Alternating Direction Multiplier Algorithm, the initial multiscale filter dictionary atoms are obtained
Figure GDA0003856912530000061

步骤2、构建小波多尺度卷积特征编码约束的稀疏角度CT重建模型;Step 2. Construct a sparse-angle CT reconstruction model constrained by wavelet multi-scale convolution feature coding;

构建的重建模型可表示为:The constructed reconstruction model can be expressed as:

Figure GDA0003856912530000062
Figure GDA0003856912530000062

其中*为卷积算子,K为卷积核尺度数,N为单个尺度下卷积核个数,A为CT系统的投影矩阵,x为待重建图像,p为稀疏投影数据,W为小波变换高频系数提取算子,λ和β为正则化参数,dn,k为多尺度滤波器字典原子,Mn,k为对应原子的特征图。Where * is the convolution operator, K is the number of convolution kernel scales, N is the number of convolution kernels at a single scale, A is the projection matrix of the CT system, x is the image to be reconstructed, p is the sparse projection data, and W is the wavelet Transform the high-frequency coefficient extraction operator, λ and β are the regularization parameters, d n, k are the multi-scale filter dictionary atoms, and M n, k are the feature maps of the corresponding atoms.

具体的,稀疏角度CT重建模型中小波变换高频系数提取算子W的操作步骤为:首先对图像进行1层的二维平稳小波变换,选用Haar小波基;然后选取高频系数部分的水平、垂直和对角三个方向的子带信号;最后对这三个方向的子带信号按照第三维度顺序叠加组合。算子W操作后所获得的为三维数据,其中第一第二维度大小与待重建图像相等,第三维度大小为3。正则化参数λ依据具体数据经验性的选取。Specifically, the operation steps of the wavelet transform high-frequency coefficient extraction operator W in the sparse angle CT reconstruction model are as follows: first, perform a two-dimensional stationary wavelet transform on the image, and select the Haar wavelet base; then select the level of the high-frequency coefficient part, The sub-band signals in three vertical and diagonal directions; finally, the sub-band signals in these three directions are superimposed and combined according to the order of the third dimension. After the operation of the operator W, the obtained data is three-dimensional data, in which the size of the first and second dimensions is equal to the image to be reconstructed, and the size of the third dimension is 3. The regularization parameter λ is selected empirically based on specific data.

步骤3、重建模型分解:Step 3, reconstruction model decomposition:

对重建模型式(2)进行固定变量分解,可获得卷积特征学习更新目标函数和待重建图像更新目标函数,分别表示为:By decomposing the fixed variables of the reconstruction model formula (2), the convolutional feature learning update objective function and the image update objective function to be reconstructed can be obtained, which are expressed as:

Figure GDA0003856912530000063
Figure GDA0003856912530000063

Figure GDA0003856912530000064
Figure GDA0003856912530000064

其中*为卷积算子,K为卷积核尺度数,N为尺度卷积核个数,A为投影矩阵,p为投影数据,W为小波变换高频系数提取算子,λ和β为正则化参数,xt为第t(0≤t)次更新后的待重建图像,

Figure GDA0003856912530000065
为第t次更新后的多尺度滤波器字典原子,
Figure GDA0003856912530000066
为第t次更新后对应原子的特征图。Among them, * is the convolution operator, K is the number of convolution kernel scales, N is the number of scale convolution kernels, A is the projection matrix, p is the projection data, W is the wavelet transform high-frequency coefficient extraction operator, λ and β are Regularization parameters, x t is the image to be reconstructed after the tth (0≤t) update,
Figure GDA0003856912530000065
is the multi-scale filter dictionary atom after the tth update,
Figure GDA0003856912530000066
is the feature map of the corresponding atom after the tth update.

具体的,在卷积特征学习更新目标函数和待重建图像更新目标函数中,当t=0时为初始值,初始多尺度滤波器字典原子及特征图由步骤1获得,初始待重建图像x0由滤波反投影(Filter Back Projection,FBP)算法重建获得。Specifically, in the convolutional feature learning update objective function and the image update objective function to be reconstructed, when t=0 is the initial value, the initial multi-scale filter dictionary atoms and feature maps are obtained by step 1, and the initial image to be reconstructed x 0 It is reconstructed by the filter back projection (Filter Back Projection, FBP) algorithm.

步骤4、交替的方式求解卷积特征学习更新目标函数和待重建图像更新目标函数获得最终的重建图像。Step 4. Alternately solve the convolution feature learning update objective function and the image to be reconstructed update objective function to obtain the final reconstructed image.

具体的,卷积特征学习更新目标函数式(3)采用交替方向乘子算法求解。令D=(d1,1,d1,2,…,dn,k)为向量化的滤波器字典,M=(M1,1,M1,2,…,Mn,k)为向量化的特征图集合,则

Figure GDA0003856912530000071
可简化表示为矩阵相乘DM(其中矩阵元素之间仍然是卷积运算),并为向量化的特征图集合M与滤波器字典D添加辅助变量C和F,则式(3)的求解可包括以下式:Specifically, the convolutional feature learning update objective function formula (3) is solved by an alternating direction multiplier algorithm. Let D=(d 1,1 ,d 1,2 ,…,d n,k ) be a vectorized filter dictionary, and M=(M 1,1 ,M 1,2 ,…,M n,k ) be Vectorized feature map set, then
Figure GDA0003856912530000071
It can be simplified as matrix multiplication DM (where the matrix elements are still convolution operations), and add auxiliary variables C and F to the vectorized feature map set M and filter dictionary D, then the solution of formula (3) can be Include the following formulas:

Figure GDA0003856912530000072
Figure GDA0003856912530000072

Figure GDA0003856912530000073
Figure GDA0003856912530000073

ut+1=ut+Mt+1-Ct+1(3-3)u t+1 =u t +M t+1 -C t+1 (3-3)

Figure GDA0003856912530000074
Figure GDA0003856912530000074

Figure GDA0003856912530000075
Figure GDA0003856912530000075

ht+1=ht+Dt+1-Ft+1(3-6)h t+1 =h t +D t+1 -F t+1 (3-6)

其中u和h为求解中的尺度化对偶辅助变量,ρ1和ρ2为拉格朗日乘子,大小可设为ρ1=50β+1,ρ2=1,Proj(·)为投影截断操作,通过对滤波器的截断操作以保证编码尺寸大小与待重建图像数据大小相同,初始化后F0=D0,C0=M0,h0=0,u0=0。式(3-1)为特征图更新,式(3-4)为滤波器字典更新,式(3-1)和式(3-4)的解均可通过三维傅里叶变换行求解可获得,式(3-2)可通过软阈值收缩算法求解获得,式(3-5)可采用三维傅里叶变换及投影截断求解获得。待重建图像更新目标函数式(4)采用抛物面替代算法求解,具体可表示为:where u and h are scaled dual auxiliary variables in the solution, ρ 1 and ρ 2 are Lagrangian multipliers, the size can be set as ρ 1 =50β+1, ρ 2 =1, Proj(·) is the projection truncation The operation is to ensure that the encoding size is the same as the size of the image data to be reconstructed through the truncation operation of the filter. After initialization, F 0 =D 0 , C 0 =M 0 , h 0 =0, u 0 =0. Equation (3-1) is the update of the feature map, and Equation (3-4) is the update of the filter dictionary. The solutions of Equation (3-1) and Equation (3-4) can be obtained by solving the three-dimensional Fourier transform row , Equation (3-2) can be obtained by the soft threshold shrinkage algorithm, and Equation (3-5) can be obtained by three-dimensional Fourier transform and projection truncation. The update objective function formula (4) of the image to be reconstructed is solved by the paraboloid substitution algorithm, which can be specifically expressed as:

xt+1=xt-[AT(Axt-p)+λWT(DM-Wxt)]/[ATAI+λ] (4-1)x t+1 =x t -[ AT (Ax t -p)+λW T (DM-Wx t )]/[ AT AI+λ] (4-1)

其中AT为CT系统的反投影算子,WT为小波高频系数逆变换操作,I为全为1的向量。最后,按顺序交替求解式(3-1)、式(3-2)、式(3-3)、式(3-4)、式(3-5)、式(3-6)和式(4-1),重复迭代,直到迭代前后待重建图像满足RMSE(xt+1-xt)≤30时停止,输出最终的重建结果图,其中RMSE(·)为均方误差计算算子。Among them, AT is the back projection operator of the CT system, W T is the wavelet high-frequency coefficient inverse transform operation, and I is a vector with all 1s. Finally, formula (3-1), formula (3-2), formula (3-3), formula (3-4), formula (3-5), formula (3-6) and formula ( 4-1), repeat the iteration until the image to be reconstructed before and after the iteration satisfies RMSE(x t+1 -x t )≤30 and stop, and output the final reconstruction result map, where RMSE( ) is the mean square error calculation operator.

效果评估准则Effect Evaluation Criteria

实验中,我们对高质量腹部及胸部图像数据进行仿真,获得不同扫描角度的模拟投影数据,并进行相应的重建。模拟扫描使用的参数为:探测器大小为960,探测器单元尺寸为0.78mm,射线源到物体中心和探测器中心的距离分别为50cm和100cm,扫描分别采集180个投影数据和120个投影数据,其它参数采用默认值。180个腹部投影数据重建中正则化参数λ与β分别为0.02和0.016,120个腹部投影数据重建中参数为0.025和0.018;180个胸部投影数据重建中正则化参数λ与β分别为0.022和0.018,120个胸部投影数据重建中参数为0.026和0.021。实验中,单个尺度下卷积核个数均为32,卷积核尺度个数为3,卷积核大小分别为8×8×3,10×10×3,12×12×3。In the experiment, we simulated high-quality abdominal and chest image data, obtained simulated projection data from different scanning angles, and carried out corresponding reconstruction. The parameters used in the simulation scan are: the detector size is 960, the detector unit size is 0.78mm, the distances from the ray source to the center of the object and the center of the detector are 50cm and 100cm respectively, and the scan collects 180 projection data and 120 projection data respectively , and other parameters adopt the default values. The regularization parameters λ and β in the reconstruction of 180 abdominal projection data are 0.02 and 0.016 respectively, the parameters in the reconstruction of 120 abdominal projection data are 0.025 and 0.018; the regularization parameters λ and β in the reconstruction of 180 chest projection data are 0.022 and 0.018 respectively , the parameters in the reconstruction of 120 chest projection data are 0.026 and 0.021. In the experiment, the number of convolution kernels at a single scale is 32, the number of convolution kernel scales is 3, and the sizes of convolution kernels are 8×8×3, 10×10×3, and 12×12×3.

附图中,所有重建后的CT图其显示窗宽为400HU(Housfield Units,HU),窗位为50HU。实验将采用主观评价和客观评价的方法验证本发明算法的有效性。主观评价:通过比较稀疏角度下腹部和胸部数据的FBP重建图、WCSC重建图和WMCR重建图,来分析平均本发明的重建效果(如图2,图3,图5和图6);通过选取感兴趣区域,画出重建图固定区域的profile曲线(如图4和图7白色线段标记区域),可以细致的观察重建组织细节的偏差。客观评价:实验将采用有参考的评价指标,如峰值信噪比(Peak Signal to Noise Ratio,PSNR)和结构相似度(Structural Similarity Index,SSIM),对实验结果进行定量比较。In the accompanying drawings, all reconstructed CT images show a window width of 400HU (Housfield Units, HU) and a window level of 50HU. The experiment will adopt the methods of subjective evaluation and objective evaluation to verify the validity of the algorithm of the present invention. Subjective evaluation: by comparing the FBP reconstruction figure, WCSC reconstruction figure and WMCR reconstruction figure of sparse angle hypogastric region and chest data, analyze the average reconstruction effect of the present invention (as Fig. 2, Fig. 3, Fig. 5 and Fig. 6); By selecting For the region of interest, draw the profile curve of the fixed area of the reconstruction map (as shown in Figure 4 and Figure 7, the area marked by the white line segment), so that the deviation of the details of the reconstructed tissue can be carefully observed. Objective evaluation: The experiment will use reference evaluation indicators, such as Peak Signal to Noise Ratio (PSNR) and Structural Similarity Index (SSIM), to quantitatively compare the experimental results.

主观评价subjective evaluation

通过观察比较图2,图3,图5和图6中CT重建图像的条状伪影强度,伪影分布,组织细节,不同组织间的对比度,重建图像纹理等特点,可以看出本发明能获得更高质量的重建图像。同时,我们从重建结果中可以看到,当扫描角度数减少后,FBP重建图受到严重的噪声干扰,无法区分组织细节,WCSC重建图和WMCR重建图中噪声伪影得到了明显抑制,且WMCR重建方法较WCSC重建方法可以更好的保持图像细节,提高对比度。随之角度数量的减少,伪影越多,重建图像质量逐渐下降,但WMCR方法依然带来较好的重建结果,明显优于WCSC算法的。By observing and comparing the stripe artifact intensity, artifact distribution, tissue details, contrast between different tissues, reconstructed image texture and other characteristics of CT reconstruction images in Fig. 2, Fig. 3, Fig. 5 and Fig. 6, it can be seen that the present invention can Obtain higher quality reconstructed images. At the same time, we can see from the reconstruction results that when the number of scanning angles is reduced, the FBP reconstruction image is severely disturbed by noise, and tissue details cannot be distinguished. The noise artifacts in the WCSC reconstruction image and WMCR reconstruction image are significantly suppressed, and WMCR Compared with the WCSC reconstruction method, the reconstruction method can better maintain the image details and improve the contrast. As the number of angles decreases, the more artifacts, the quality of the reconstructed image gradually decreases, but the WMCR method still brings better reconstruction results, which is obviously better than that of the WCSC algorithm.

客观评价objective comment

在使用主观评价本发明方法在稀疏角度扫描CT重建中的有效性的同时,实验将进一步采用PSNR和SSIM两个量化指标对重建图像进行评价,以量化确认本发明方法的有效性。PSNR和SSIM的计算方法如下:While subjectively evaluating the effectiveness of the method of the present invention in sparse angle scanning CT reconstruction, the experiment will further use two quantitative indicators of PSNR and SSIM to evaluate the reconstructed image to quantitatively confirm the effectiveness of the method of the present invention. PSNR and SSIM are calculated as follows:

Figure GDA0003856912530000081
Figure GDA0003856912530000081

Figure GDA0003856912530000091
Figure GDA0003856912530000091

其中xT为最后一次更新的待重建图像,xr为用于模拟的高质量参考图,N为图像像素总数;Hmax为xr的最大值,μxT和μxr分别表示CT图像xT和xr中总像素CT值的平均值;σxT和σxr分别表示CT图像xT和xr中总像素CT值的标准差值,σxTr为CT图像xT与xr的协方差,常数C1=(0.01×Hmax)2,C2=(0.03×Hmax)2。以用于模拟的高质量图像为参考图,计算不同数据重建图像的PSNR和SSIM值,其结果如表1所示。where x T is the last updated image to be reconstructed, x r is the high-quality reference image used for simulation, N is the total number of image pixels; H max is the maximum value of x r , μ xT and μ xr respectively represent the CT image x T and the mean value of the total pixel CT values in x r ; σ xT and σ xr respectively represent the standard deviation of the total pixel CT values in CT images x T and x r , σ xTr is the covariance of CT images x T and x r , Constants C 1 =(0.01×H max ) 2 , C 2 =(0.03×H max ) 2 . Taking the high-quality image used for simulation as a reference image, calculate the PSNR and SSIM values of the reconstructed images with different data, and the results are shown in Table 1.

表1Table 1

Figure GDA0003856912530000092
Figure GDA0003856912530000092

从表1中可以看出,在模拟稀疏角度下腹部和胸部数据重建中,FBP重建图像的量化指标最差,WCSC重建结果均有一定的提高,而采用本发明WMCR方法可获得更高的SSIM和PSNR值(本发明WMCR方法与WCSC方法结果相比,在180个角度扫描数据实验中,PSNR约高出1.4dB左右,SSIM约高出0.01左右,在120个角度扫描数据实验中,PSNR约高出.9dB左右,SSIM约高出0.01左右)。从图4和图7中可以看出,在所选像素中(图4(a)和图7(a)中图像白色线段标记区域,Ref为参考图像),WMCR重建图中组织边界像素值跳跃更加明显,组织边界更锐利,曲线走势更接近参考图像。从上述实验可以看到,在相同的稀疏角度扫描条件下本发明方法可获得更少伪影的CT重建图像,且稳定性高,具有一定的应用前景。It can be seen from Table 1 that in the data reconstruction of the lower abdomen and chest at simulated sparse angles, the quantitative index of the FBP reconstruction image is the worst, and the WCSC reconstruction results have been improved to a certain extent, and the WMCR method of the present invention can obtain a higher SSIM With PSNR value (WMCR method of the present invention compares with WCSC method result, in 180 angle scan data experiments, PSNR about 1.4dB higher, SSIM about 0.01 higher, in 120 angle scan data experiments, PSNR about about .9dB higher and SSIM about 0.01 higher). It can be seen from Fig. 4 and Fig. 7 that in the selected pixels (in Fig. 4(a) and Fig. 7(a), the white line segment mark area of the image, Ref is the reference image), the tissue boundary pixel value jumps in the WMCR reconstruction map It is more obvious, the tissue boundary is sharper, and the curve trend is closer to the reference image. It can be seen from the above experiments that under the same sparse angle scanning condition, the method of the present invention can obtain a CT reconstruction image with fewer artifacts, and has high stability, which has a certain application prospect.

以上示意性的对本发明及其实施方式进行了描述,该描述没有限制性,附图中所示的也只是本发明的实施方式之一,实际的结构并不局限于此。所以,如果本领域的普通技术人员受其启示,在不脱离本发明创造宗旨的情况下,不经创造性的设计出与该技术方案相似的结构方式及实施例,均应属于本发明的保护范围。The above schematically describes the present invention and its implementation, which is not restrictive, and what is shown in the drawings is only one of the implementations of the present invention, and the actual structure is not limited thereto. Therefore, if a person of ordinary skill in the art is inspired by it, without departing from the inventive concept of the present invention, without creatively designing a structural mode and embodiment similar to the technical solution, it shall all belong to the protection scope of the present invention .

Claims (1)

1.一种基于小波多尺度卷积特征编码的稀疏角度CT重建方法,其特征在于,包括以下步骤:1. A sparse angle CT reconstruction method based on wavelet multi-scale convolution feature coding, characterized in that, comprising the following steps: 步骤1、获取初始多尺度滤波器字典原子;Step 1. Obtain the initial multi-scale filter dictionary atom; 对给定的高质量CT样本图像xs进行小波变换,获得高频和低频小波系数,其中小波变换采用1层的二维平稳小波变换,选用Haar小波基;高频系数部分表示为
Figure FDA0003856912520000011
Figure FDA0003856912520000012
fv 0
Figure FDA0003856912520000013
分别为水平、垂直和对角三个方向的子带信号;对F0进行多尺度卷积特征学习,获取初始的多尺度滤波器字典原子
Figure FDA0003856912520000014
学习模型表示为:
Carry out wavelet transform on a given high-quality CT sample image x s to obtain high-frequency and low-frequency wavelet coefficients, where the wavelet transform uses a two-dimensional stationary wavelet transform with a layer of Haar wavelet basis; the high-frequency coefficient part is expressed as
Figure FDA0003856912520000011
Figure FDA0003856912520000012
f v 0 and
Figure FDA0003856912520000013
are the sub-band signals in the horizontal, vertical and diagonal directions respectively; perform multi-scale convolution feature learning on F 0 to obtain the initial multi-scale filter dictionary atoms
Figure FDA0003856912520000014
The learning model is expressed as:
Figure FDA0003856912520000015
Figure FDA0003856912520000015
其中*为卷积算子,K为卷积核尺度数,N为单个尺度下卷积核个数,
Figure FDA0003856912520000016
为对应原子的特征图,β为正则化参数;学习模型式(1)采用交替方向乘子算法求解,获取初始多尺度滤波器字典原子;其中多尺度滤波器参数为:卷积核尺度数范围为2≤K≤5,单个尺度下卷积核个数取值范围为32≤N≤64,卷积核大小可选范围为6×6×3至14×14×3;
Where * is the convolution operator, K is the number of convolution kernel scales, and N is the number of convolution kernels at a single scale,
Figure FDA0003856912520000016
is the feature map corresponding to the atom, and β is the regularization parameter; the learning model formula (1) is solved by the alternate direction multiplier algorithm to obtain the initial multi-scale filter dictionary atoms; the multi-scale filter parameters are: the range of the convolution kernel scale number 2≤K≤5, the value range of the number of convolution kernels under a single scale is 32≤N≤64, and the optional range of convolution kernel size is 6×6×3 to 14×14×3;
步骤2、构建小波多尺度卷积特征编码约束的稀疏角度CT重建模型;构建的重建模型表示为:Step 2. Construct a sparse angle CT reconstruction model constrained by wavelet multi-scale convolution feature coding; the constructed reconstruction model is expressed as:
Figure FDA0003856912520000021
Figure FDA0003856912520000021
其中*为卷积算子,K为卷积核尺度数,N为单个尺度下卷积核个数,A为CT系统的投影矩阵,x为待重建图像,p为稀疏投影数据,W为小波变换高频系数提取算子,λ和β为正则化参数,dn,k为多尺度滤波器字典原子,Mn,k为对应的特征图;其中小波变换高频系数提取算子W的操作步骤为:首先对图像进行1层的二维平稳小波变换,选用Haar小波基;然后选取高频系数部分的水平、垂直和对角三个方向的子带信号;最后对这三个方向的子带信号按照第三维度顺序叠加组合;算子W操作后所获得的为三维数据,其中第一维度第二维度大小与待重建图像相等,第三维度大小为3;Where * is the convolution operator, K is the number of convolution kernel scales, N is the number of convolution kernels at a single scale, A is the projection matrix of the CT system, x is the image to be reconstructed, p is the sparse projection data, and W is the wavelet Transform the high-frequency coefficient extraction operator, λ and β are regularization parameters, d n, k are the multi-scale filter dictionary atoms, M n, k are the corresponding feature maps; the operation of the wavelet transform high-frequency coefficient extraction operator W The steps are as follows: firstly carry out 1-layer two-dimensional stationary wavelet transform on the image, and select the Haar wavelet base; then select the sub-band signals in the horizontal, vertical and diagonal directions of the high-frequency coefficient part; finally, the sub-band signals in the three directions The band signals are superimposed and combined according to the order of the third dimension; after the operation of the operator W, the obtained data is three-dimensional data, in which the size of the first dimension and the second dimension are equal to the image to be reconstructed, and the size of the third dimension is 3; 步骤3、重建模型分解:对重建模型进行固定变量分解,获得卷积特征学习更新目标函数和待重建图像更新目标函数;分别表示为:Step 3. Reconstruction model decomposition: Decompose the reconstruction model with fixed variables to obtain the convolution feature learning update objective function and the image update objective function to be reconstructed; respectively expressed as:
Figure FDA0003856912520000022
Figure FDA0003856912520000022
Figure FDA0003856912520000023
Figure FDA0003856912520000023
其中*为卷积算子,K为卷积核尺度数,N为单个尺度下卷积核个数,A为CT系统的投影矩阵,x为待重建图像,p为稀疏投影数据,W为小波变换高频系数提取算子,λ和β为正则化参数,xt为第t(0≤t)次更新后的待重建图像,
Figure FDA0003856912520000031
为第t次更新后的多尺度滤波器字典原子,
Figure FDA0003856912520000032
为第t次更新后对应原子的特征图;其中当t=0时为初始值,初始多尺度滤波器字典原子由步骤1获得,初始待重建图像x0由斜坡滤波器的滤波反投影算法重建获得;
Where * is the convolution operator, K is the number of convolution kernel scales, N is the number of convolution kernels at a single scale, A is the projection matrix of the CT system, x is the image to be reconstructed, p is the sparse projection data, and W is the wavelet Transform the high-frequency coefficient extraction operator, λ and β are regularization parameters, x t is the image to be reconstructed after the tth (0≤t) update,
Figure FDA0003856912520000031
is the multi-scale filter dictionary atom after the tth update,
Figure FDA0003856912520000032
is the feature map of the corresponding atom after the t-th update; where t=0 is the initial value, the initial multi-scale filter dictionary atom is obtained from step 1, and the initial image x 0 to be reconstructed is reconstructed by the filter back projection algorithm of the slope filter get;
步骤4、交替的方式求解卷积特征学习更新目标函数和待重建图像更新目标函数获得最终的重建结果图;其中卷积特征学习更新目标函数式(3)采用交替方向乘子算法求解,待重建图像更新目标函数式(4)采用抛物面替代算法求解;当迭代前后待重建图像满足RMSE(xt+1-xt)≤30时停止,输出最终的重建结果图,其中RMSE(·)为均方误差计算算子。Step 4. Alternately solve the convolutional feature learning update objective function and the image update objective function to be reconstructed to obtain the final reconstruction result graph; where the convolution feature learning update objective function formula (3) is solved by the alternate direction multiplier algorithm, and the image to be reconstructed Image update objective function formula (4) is solved by paraboloid substitution algorithm; stop when the image to be reconstructed before and after iteration satisfies RMSE(x t+1 -x t )≤30, and output the final reconstruction result map, where RMSE( ) is mean Square error calculation operator.
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