CN113024661A - Insulin purification equipment - Google Patents
Insulin purification equipment Download PDFInfo
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- CN113024661A CN113024661A CN202110227938.7A CN202110227938A CN113024661A CN 113024661 A CN113024661 A CN 113024661A CN 202110227938 A CN202110227938 A CN 202110227938A CN 113024661 A CN113024661 A CN 113024661A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
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Abstract
The invention relates to the technical field of medicine purification equipment, in particular to insulin purification equipment, wherein supporting legs are arranged at the bottom of a drying box at equal intervals, a stirring tank is arranged on the left side of the top of the drying box, a gas purifier is arranged on the right side of the top of the drying box, a vertical plate is fixed in the middle of the top of the drying box, a top plate is rotatably arranged in the middle of the top of the vertical plate, a first motor is arranged on one side of the top plate, the output end of the first motor extends into the stirring tank, a rotating shaft is fixedly arranged inside the stirring tank, driven rotating shafts are rotatably arranged at the bottom of the top plate, the number of the driven rotating shafts is two, the rotating shaft is located between the two driven rotating shafts, double belt pulleys are arranged at the top of the outer wall of the rotating shaft, single belt pulleys correspondingly matched with the double belt pulleys are. The present invention has the effect of increasing the rate of insulin purification.
Description
Technical Field
The invention relates to the technical field of medical purification equipment, in particular to insulin purification equipment.
Background
Insulin is a protein hormone secreted by the beta cells of the islets of langerhans in the pancreas stimulated by endogenous or exogenous substances such as glucose, lactose, ribose, arginine, glucagon, etc. Insulin is the only hormone in the body which reduces blood sugar and promotes the synthesis of glycogen, fat and protein. Exogenous insulin is mainly used for treating diabetes.
The production process of the artificial insulin mainly comprises the following steps: 1. strain expanding culture, namely activating and primarily expanding culture of strains taken out from a strain bank; 2. seed tank culture, in which the strain is further expanded and cultured in the seed tank, and is transferred into a fermentation tank for culture when the strain reaches logarithmic phase; 3. fermentation tank culture-control in two stages, wherein in the first stage, the thalli are enriched mainly by controlling dissolved oxygen and supplementing glycerol, in the second stage, the thalli are subjected to high-density expression of a target product by supplementing methanol, and the content of the target product is detected by HPLC; 4. and (4) performing solid-liquid separation on the fermentation liquor, namely allowing the target product to exist in the supernatant of the fermentation liquor, and mainly controlling the yield of the target product. 5. P1 purification, namely removing pigments and foreign proteins in the fermentation supernatant respectively through two-step column chromatography, and controlling the yield of a target product by using an ultraviolet detector, wherein main reagents are ethanol and isopropanol; precipitating and drying P1, adjusting the pH value to precipitate P1, and then centrifugally drying to obtain an intermediate chemical solid; p2 purification-temperature control for transpeptidation reaction, wherein the main reagent is DMSO and 1, 4-butanediol, and then purification is carried out by column chromatography, and the main reagent is isopropanol; p2 precipitation, drying, adjusting pH value to precipitate P2, and then centrifugally drying to obtain an intermediate solid. 6. Uncapping, namely, carrying out uncapping reaction by controlling humidity and temperature to obtain a final product, namely a semisolid insulin, wherein the main reagent is acetone; 7. crude purification of finished products, namely purifying insulin by two-step column chromatography, wherein the purified insulin is concentrated by Tris-HCI and isopropanol as reagents, and is transferred to the next procedure by a pipeline to refine the crude insulin by a preparative chromatogram, and the main reagent is chromatographic acetonitrile; 8. fine purification of finished products, namely, after two-step crystallization, filtering and sterilizing to a hundred-grade area through a pipeline, and carrying out primary crystallization and water washing on insulin finished products; 9. and (4) filtering and freeze-drying, namely filtering, sterilizing and freeze-drying the washed insulin to obtain the finished insulin product.
From the above, in the production process of artificial insulin, purification is an important link, and equipment for purifying insulin in the prior art is simple and crude, and the stirring effect is not good, so that the reaction effect of reactants is not good, and the yield of insulin is reduced. To this end, we propose an apparatus for purifying insulin.
Disclosure of Invention
The present invention is directed to an insulin purification device to solve the above-mentioned problems of the background art.
In order to achieve the purpose, the invention provides the following technical scheme: the insulin purification equipment comprises a drying box, wherein supporting legs are equidistantly mounted at the bottom of the drying box, an agitator tank is arranged on the left side of the top of the drying box, a gas purifier is arranged on the right side of the top of the drying box, a vertical plate is fixed in the middle of the top of the drying box, a top plate is rotatably mounted in the middle of the top of the vertical plate, a first motor is mounted on one side of the top plate, the output end of the first motor extends into the agitator tank and is fixedly provided with a rotating shaft, driven rotating shafts are rotatably mounted at the bottom of the top plate and are provided with two rotating shafts, the rotating shafts are located between the two driven rotating shafts, double belt pulleys are mounted at the top of the outer wall of the rotating shaft, single belt pulleys correspondingly matched with the double belt pulleys are mounted on the outer wall of the driven;
rectangular frames are symmetrically arranged on two sides of the outer wall of the rotating shaft, cross rods are uniformly arranged in the rectangular frames, rectangular supports are respectively arranged at two ends, away from the outer wall of the driven rotating shaft, of the two outer walls of the driven rotating shaft, scraping plates for scraping crystals on the inner wall of the stirring tank are respectively fixed at the rectangular supports and the other ends of the rectangular frames, a top cover plate is arranged at the top of the stirring tank through a flange, the double belt pulleys and the single belt pulley are both positioned above the top cover plate, a supporting frame for fixing the stirring tank is fixed at the left side of the vertical plate, a heat insulation plate is fixed at the top of the supporting frame and is sleeved on the outer wall of the stirring tank, a feeding pipe is arranged at;
the drying oven is characterized in that a longitudinal partition plate is arranged in the middle of the inside of the drying oven, honeycomb plates are fixed between the left side and the right side of the longitudinal partition plate and the inner wall of the left side and the right side of the drying oven respectively, the inside of the drying oven is divided into a left draining cavity and a right drying cavity by the longitudinal partition plate, the bottom of the discharge pipe extends to the inside of the draining cavity, a solenoid valve is installed inside the discharge pipe, a water storage cylinder is arranged at the top of the inner part of the draining cavity, a crystallization cylinder is rotatably installed inside the water storage cylinder, the distance between the bottom of the crystallization cylinder and the bottom of the inner wall of the water storage cylinder is not less than 20CM, draining holes are uniformly formed in the bottom of the crystallization cylinder, a drain pipe is installed on one side of the bottom of the water storage cylinder, the bottom of the drain pipe extends to the outside of the drying oven, the utility model discloses a drying oven, including waterlogging caused by excessive rainfall chamber, conveying pipe, drying cabinet, honeycomb panel top, drying cabinet, waterlogging caused by excessive rainfall chamber bottom rotation and installation bull stick, the bull stick bottom extends to inside the water storage section of thick bamboo, just crystallization section of thick bamboo bottom fixed connection, bull stick outer wall bottom be fixed with initiative bevel gear intermeshing's passive bevel gear, the conveying pipe is installed at the inside top of drying cabinet, conveying pipe one end extends to waterlogging caused by excessive rainfall chamber inside is fixed with the suction nozzle that is used for adsorbing the crystallization, the conveying pipe other end extends to the stoving intracavity portion is fixed with the nozzle that blows off the crystallization, stoving intracavity portion sets up the drying cabinet that is used for placing the crystallization, the micropore has evenly been seted up on the drying cabinet, the drying cabinet is installed honeycomb panel top, the inside bottom in stoving.
As the further setting of above-mentioned scheme, gas purifier is including tertiary cartridge filter, tertiary cartridge filter is first cartridge filter, second cartridge filter and third cartridge filter from supreme down in proper order. .
As a further arrangement of the scheme, a metal wire mesh is installed at the bottom of the interior of the first filter cylinder, and a non-woven fabric mesh is installed at the top of the interior of the first filter cylinder.
As the further setting of above-mentioned scheme, second cartridge filter internally mounted has the filter, second cartridge filter internally mounted has the purification casing, it has the active carbon granule to purify casing inside packing.
As a further arrangement of the scheme, the right side of the top of the drying box is provided with a circulation hole, and the circulation hole is positioned in the middle of the bottom of the gas purifier.
As a further arrangement of the scheme, a filtering cover is installed in the middle of the top of the gas purifier in a threaded mode, and filtering holes are evenly formed in the filtering cover.
As a further arrangement of the scheme, an ear seat is fixed at the top of the right end of the vertical plate, and positioning holes matched with each other are formed in the ear seat and the top plate.
As a further arrangement of the scheme, an electric heating wire net is uniformly installed on the inner wall of the heat insulation plate, a temperature sensor is installed inside the stirring tank, and the electric heating wire net and the temperature sensor are respectively electrically connected with an external control device through a wire.
According to the scheme, the radian of the scraper is consistent with that of the inner wall of the stirring tank, the outer wall of the scraper is uniformly provided with the edge strips, and the edge strips are in contact with the inner wall of the stirring tank.
As a further arrangement of the scheme, the top of the inner wall of the water storage cylinder is provided with a circular groove, the middle of the outer wall of the crystallizing cylinder is provided with a circular ring protruding outwards, and the circular groove is matched with the circular ring.
Compared with the prior art, the invention has the beneficial effects that:
1. according to the stirring tank, the first motor is started, the amplitude of forward rotation and reverse rotation of the first motor is set to be not more than 45 degrees, the rotating shaft rotates to drive the double belt pulleys to rotate, the single belt pulley is driven to rotate through the belt, the rotating shaft is driven to rotate, the rectangular frame rotates to stir solution in the stirring tank when the rotating shaft rotates, the reaction speed is improved, the stirring effect is improved due to the arrangement of the cross rod, the rectangular support rotates when the rotating shaft rotates to stir the solution in the stirring tank, the rectangular frame and the rectangular support rotate to drive the scraper to scrape crystals adhered to the inner portion of the stirring tank, waste is reduced, and the purification efficiency is improved.
2. When the crystallizer is used, the second motor is started to rotate the driving conical gear to drive the driven conical gear meshed with the driving conical gear to rotate, so that the rotating rod rotates to drive the crystallizing cylinder to rotate, the crystallizing cylinder rotates in the water storage cylinder, redundant water in crystals enters the water storage cylinder through the water draining holes under the action of centrifugal force and finally flows out through the water draining pipe, and the water in crystals in the crystallizing cylinder is less, so that the next operation is facilitated.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic view of a first perspective structure of the present invention;
FIG. 2 is a schematic view of a second perspective structure of the present invention;
FIG. 3 is a front view of the present invention;
FIG. 4 is a schematic structural diagram of a third perspective of the present invention;
FIG. 5 is a schematic view of the overall structure of the rotating shaft and the driven rotating shaft according to the present invention;
FIG. 6 is a schematic view of the internal structure of the stirring tank of the present invention;
FIG. 7 is a schematic view of the internal structure of the drying box and the gas purifier according to the present invention;
FIG. 8 is a schematic view of the inner structure of a draining chamber according to the present invention;
FIG. 9 is a schematic view of an internal structure of a drying chamber according to the present invention;
FIG. 10 is a schematic view of the structure of the present invention at A.
In the figure: 1. a drying oven; 111. an air inlet; 112. a draining cavity; 113. a drying cavity; 114. a flow-through hole; 2. a stirring tank; 211. a discharge pipe; 3. a gas purifier; 4. a vertical plate; 41. an ear mount; 5. a top plate; 6. a first motor; 7. a rotating shaft; 8. a driven shaft; 9. a feed pipe; 10. a support frame; 11. a thermal insulation board; 12. a second motor; 13. supporting legs; 14. a belt; 15. a filter cover; 16. positioning holes; 17. a top cover plate; 18. a double belt pulley; 19. a single pulley; 20. a rectangular bracket; 21. purifying the shell; 22. a rectangular frame; 23. a cross bar; 24. a squeegee; 25. a longitudinal partition; 26. a honeycomb panel; 27. a water storage cylinder; 271. a drain pipe; 28. a driving bevel gear; 29. a crystallization cylinder; 30. a rotating rod; 31. a driven bevel gear; 32. a transport pipe; 33. a drying oven; 34. a drying lamp; 35. a wire mesh; 36. a nonwoven web; 37. a filter plate.
Detailed Description
In order to make the technical solutions better understood by those skilled in the art, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only partial embodiments of the present application, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail with reference to the accompanying drawings 1 to 10, in conjunction with the embodiments.
Example 1
This embodiment 1 introduces an insulin purifying apparatus, which includes a drying oven 1, wherein supporting legs 13 are equidistantly installed at the bottom of the drying oven 1, an agitator tank 2 is installed on the left side of the top of the drying oven 1, a gas purifier 3 is installed on the right side of the top of the drying oven 1, a vertical plate 4 is fixed in the middle of the top of the drying oven 1, a top plate 5 is rotatably installed in the middle of the top of the vertical plate 4, an ear seat 41 is fixed at the top of the right end of the vertical plate 4, the ear seat 41 and the top plate 5 are both provided with positioning holes 16 that are mutually matched, during installation, the top plate 5 can be fixed by sequentially passing through the positioning holes 16 on the top plate 5 and the positioning holes 16 on the ear seat 41 through bolts, a first motor 6 is installed on one side of the top plate 5, an output end of the first motor 6 extends to the inside of the agitator tank 2 and, two driven rotating shafts 8 are arranged, the rotating shaft 7 is positioned between the two driven rotating shafts 8, double belt pulleys 18 are arranged at the top of the outer wall of the rotating shaft 7, single belt pulleys 19 correspondingly matched with the double belt pulleys 18 are arranged on the outer wall of each driven rotating shaft 8, and belts 14 are respectively sleeved between the two single belt pulleys 19 and the double belt pulleys 18;
rectangular frames 22 are symmetrically arranged on two sides of the outer wall of the rotating shaft 7, cross rods 23 are uniformly arranged in the rectangular frames 22, two rectangular supports 20 are respectively arranged at one end of the outer wall of the driven rotating shaft 8, which is away from the other end of each rectangular support 20, a scraper 24 used for scraping crystals on the inner wall of the stirring tank 2 is fixed at the other end of each rectangular support 22, the radian of each scraper is consistent with that of the inner wall of the stirring tank 2, blades are uniformly arranged on the outer wall of each scraper 24, the blades are in contact with the inner wall of the stirring tank 2, a top cover plate 17 is arranged at the top of the stirring tank 2 through a flange, the double belt pulleys 18 and the single belt pulley 19 are both positioned above the top cover plate 17, a support frame 10 used for fixing the stirring tank 2 is fixed on the left side of the vertical plate 4, a heat insulation board 11 is fixed, electric heat silk screen is evenly installed to 11 inner walls of heated board, 2 internally mounted of agitator tank have temperature sensor, electric heat silk screen with temperature sensor passes through wire and external control device electric connection respectively, and external control device is common computer, opens electric heat silk screen through external control device, makes 2 inside temperature of agitator tank rise, thereby improves the reaction rate of 2 inside reactants of agitator tank, senses the temperature not in the default scope when 2 inside wind temperature sensor of agitator tank, gives external control device with this information transfer, through the power of external control device adjustment electric heat silk screen, thereby adjusts the temperature, inlet pipe 9 is installed at 2 left side tops of agitator tank, agitator tank 2 bottoms are fixed with discharging pipe 211, during the use, start first motor 6, set up the amplitude of first motor 6 corotation reversal and is no more than 45, make pivot 7 rotate, pivot 7 rotates and drives two belt pulleys 18 and rotate, it rotates to drive single belt pulley 19 through belt 14, thereby drive pivot 7 and rotate, when passive pivot 8 rotates, rectangular frame 22 rotates, stir 2 inside solutions of agitator tank, improve reaction rate, the horizontal pole 23 of setting, the stirring effect has been improved, when pivot 7 rotates, rectangular support 20 rotates, stir 2 inside solutions of agitator tank, rectangular frame 22 and rectangular support 20 rotate, drive scraper blade 24 and strike off the crystal of 2 inside adhesions of agitator tank.
The drying oven is characterized in that a longitudinal partition plate 25 is arranged in the middle of the inside of the drying oven 1, honeycomb plates 26 are fixed between the left side and the right side of the longitudinal partition plate 25 and the inner wall of the left side and the right side of the drying oven 1 respectively, the longitudinal partition plate 25 separates the inside of the drying oven 1 into a left draining cavity 112 and a right side drying cavity 113, the bottom of the discharge pipe 211 extends into the draining cavity 112, an electromagnetic valve is installed inside the discharge pipe 211, a water storage cylinder 27 is arranged at the top inside the draining cavity 112, a crystallization cylinder 29 is rotatably installed inside the water storage cylinder 27, an annular groove is formed in the top of the inner wall of the water storage cylinder 27, an outwardly convex ring is arranged in the middle of the outer wall of the crystallization cylinder 29, the annular groove is matched with the ring, the distance between the bottom of the crystallization cylinder 29 and the bottom of the inner wall of the water storage cylinder 27 is not less than 20CM, draining holes, the bottom of the drain pipe 271 extends to the outside of the drying box 1, the bottom of the left end of the drying box 1 is provided with the second motor 12, the output end of the second motor 12 extends to the inside of the draining cavity 112 is fixed with the active bevel gear 28, the bottom of the draining cavity 112 is rotatably provided with the rotating rod 30, the bottom of the rotating rod 30 extends to the inside of the water storage cylinder 27, the bottom of the crystallization cylinder 29 is fixedly connected, the bottom of the outer wall of the rotating rod 30 is fixed with the passive bevel gear 31 which is meshed with the active bevel gear 28, when the stirring tank is used, the solution and the crystal which have good reaction in the stirring tank 2 enter the crystallization cylinder 29 through the discharge pipe 211, the solution enters the inside of the water storage cylinder 27 through the draining hole on the crystallization cylinder 29, finally flows out through the drain pipe 271, the crystal is intercepted by the crystallization cylinder 29, the second motor 12 is opened to rotate the active bevel gear 28, the driven bevel gear 31 that drives and mesh with it rotates for bull stick 30 rotates, and bull stick 30 rotates, drives crystallization cylinder 29 and rotates, and crystallization cylinder 29 rotates at a water storage cylinder 27 inside, and unnecessary moisture enters into a water storage cylinder 27 inside through the waterlogging caused by excessive rainfall hole under the effect of centrifugal force in the crystallization, flows out through drain pipe 271 at last, makes the moisture less in the inside crystallization of crystallization cylinder 29.
Example 2
This embodiment 2 introduces an insulin purification device, which includes a drying oven 1, wherein support legs 13 are equidistantly installed at the bottom of the drying oven 1, an agitator tank 2 is installed on the left side of the top of the drying oven 1, a gas purifier 3 is installed on the right side of the top of the drying oven 1, a vertical plate 4 is fixed in the middle of the top of the drying oven 1, a top plate 5 is rotatably installed in the middle of the top of the vertical plate 4, a first motor 6 is installed on one side of the top plate 5, a rotating shaft 7 is fixed inside the agitator tank 2 by extending the output end of the first motor 6, a driven rotating shaft 8 is rotatably installed at the bottom of the top plate 5, two driven rotating shafts 8 are provided, the rotating shaft 7 is located between the two driven rotating shafts 8, two belt pulleys 18 are installed on the top of the outer wall of the rotating shaft 7, single belt pulleys 19 correspondingly, the belt 14 is respectively sleeved between the two single belt pulleys 19 and the two double belt pulleys 18, a longitudinal partition plate 25 is arranged in the middle inside the drying oven 1, honeycomb plates 26 are fixed between the left side and the right side of the longitudinal partition plate 25 and the inner walls of the left side and the right side of the drying oven 1, the longitudinal partition plate 25 divides the inside of the drying oven 1 into a draining cavity 112 on the left side and a drying cavity 113 on the right side, a conveying pipe 32 is installed at the top inside the drying oven 1, one end of the conveying pipe 32 extends into the draining cavity 112 and is fixed with a suction nozzle for adsorbing crystals, the other end of the conveying pipe 32 extends into the drying cavity 113 and is fixed with a nozzle for blowing out the crystals, the drying cavity 113 is internally provided with a drying oven 33 for placing the crystals, micropores are uniformly formed in the drying oven 33, the drying oven 33 is installed at the top of the honeycomb plates 26, and a drying lamp 34 for drying the crystals is installed at the bottom, air inlet holes 111 are uniformly formed in the bottom of the right end of the drying box 1, crystals in the crystallization cylinder 29 are conveyed to the inside of the drying box 33 through the conveying pipe 32, the drying lamp 34 is turned on, the drying lamp 34 dries the drying box 33, gas generated during drying enters the gas purifier 3 through the circulation hole 114 and is purified by the gas purifier 3, harmful substances and peculiar smell in the gas are adsorbed, and finally the purified gas is discharged through the filter cover 15.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. An insulin purification device, comprising a drying cabinet (1), characterized in that: supporting legs (13) are installed at the bottom of the drying box (1) at equal intervals, an agitator tank (2) is arranged on the left side of the top of the drying box (1), a gas purifier (3) is arranged on the right side of the top of the drying box (1), a vertical plate (4) is fixed in the middle of the top of the drying box (1), a top plate (5) is installed in the middle of the top of the vertical plate (4) in a rotating mode, a first motor (6) is installed on one side of the top plate (5), the output end of the first motor (6) extends to a rotating shaft (7) fixed in the agitator tank (2), a driven rotating shaft (8) is installed at the bottom of the top plate (5) in a rotating mode, two driven rotating shafts (8) are arranged, the rotating shaft (7) is located between the two driven rotating shafts (8), two belt pulleys (18) are installed at the top of the outer wall of the rotating shaft (7), single, a belt (14) is sleeved between the two single belt pulleys (19) and the double belt pulleys (18) respectively;
the improved stirring tank is characterized in that rectangular frames (22) are symmetrically arranged on two sides of the outer wall of the rotating shaft (7), a cross rod (23) is uniformly arranged in each rectangular frame (22), two rectangular supports (20) are respectively arranged at one end of the outer wall of the driven rotating shaft (8) away from each other, the rectangular supports (20) and the other end of each rectangular frame (22) are respectively fixed with a scraper (24) used for scraping crystallization of the inner wall of the stirring tank (2), a top cover plate (17) is arranged at the top of the stirring tank (2) through a flange, the double belt pulleys (18) and the single belt pulley (19) are respectively positioned above the top cover plate (17), a support frame (10) used for fixing the stirring tank (2) is fixed on the left side of the vertical plate (4), a heat insulation plate (11) is fixed at the top of the support frame (10), the heat insulation plate (11) is sleeved on the outer wall of the, a discharge pipe (211) is fixed at the bottom of the stirring tank (2);
the drying oven is characterized in that a longitudinal partition plate (25) is arranged in the middle of the inside of the drying oven (1), honeycomb plates (26) are fixed between the left side and the right side of the longitudinal partition plate (25) and the inner wall of the left side and the right side of the drying oven (1), the longitudinal partition plate (25) separates the inside of the drying oven (1) into a left draining cavity (112) and a right drying cavity (113), the bottom of the discharging pipe (211) extends to the inside of the draining cavity (112), an electromagnetic valve is arranged inside the discharging pipe (211), a water storage cylinder (27) is arranged at the top of the inside of the draining cavity (112), a crystallization cylinder (29) is rotatably arranged inside the water storage cylinder (27), the bottom of the crystallization cylinder (29) and the distance between the bottoms of the inner walls of the water storage cylinder (27) are not less than 20CM, draining holes are uniformly formed in the bottom of the crystallization cylinder (29), and a drain pipe, the utility model discloses a drying oven, including a drying oven, drain pipe (271), second motor (12) are installed to drain pipe (271) bottom extends to drying oven (1) outside, second motor (12) output extends to draining chamber (112) inside is fixed with initiative conical gear (28), draining chamber (112) bottom is rotated and is installed bull stick (30), bull stick (30) bottom extends to inside water storage tube (27), just crystallization tube (29) bottom fixed connection, bull stick (30) outer wall bottom be fixed with initiative conical gear (28) intermeshing's passive conical gear (31), transport pipe (32) are installed at drying oven (1) inside top, transport pipe (32) one end extends to draining chamber (112) inside is fixed with the suction nozzle that is used for adsorbing the crystallization, transport pipe (32) other end extends to drying chamber (113) inside is fixed with the nozzle that blows off the crystallization, drying chamber (113) inside sets up drying cabinet (33) that is used for placing the crystallization, evenly seted up the micropore on drying cabinet (33), drying cabinet (33) are installed honeycomb panel (26) top, drying chamber (113) inside bottom is installed and is used for drying the stoving lamp (34) of crystal thing, inlet port (111) have evenly been seted up to drying cabinet (1) right-hand member bottom.
2. An insulin purification device according to claim 1, wherein: gas purifier (3) are including tertiary cartridge filter, tertiary cartridge filter is from supreme first cartridge filter, second cartridge filter and the third cartridge filter of being in proper order down.
3. An insulin purification device according to claim 2, wherein: and a metal wire mesh (35) is arranged at the bottom of the interior of the first filter cartridge, and a non-woven fabric mesh (36) is arranged at the top of the interior of the first filter cartridge.
4. An insulin purification device according to claim 2, wherein: the second cartridge filter internally mounted has filter (37), second cartridge filter internally mounted has purification casing (21), it has the active carbon granule to purify casing (21) inside packing.
5. An insulin purification device according to claim 1, wherein: the right side of the top of the drying box (1) is provided with a circulation hole (114), and the circulation hole (114) is positioned in the middle of the bottom of the gas purifier (3).
6. An insulin purification device according to claim 1, wherein: the middle of the top of the gas purifier (3) is provided with a filtering cover (15) in a threaded manner, and filtering holes are uniformly formed in the filtering cover (15).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110227938.7A CN113024661B (en) | 2021-03-02 | 2021-03-02 | Insulin purification equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110227938.7A CN113024661B (en) | 2021-03-02 | 2021-03-02 | Insulin purification equipment |
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| CN113024661A true CN113024661A (en) | 2021-06-25 |
| CN113024661B CN113024661B (en) | 2023-01-06 |
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