CN112992323B - Sperm supply management system for sperm bank - Google Patents
Sperm supply management system for sperm bank Download PDFInfo
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- CN112992323B CN112992323B CN202110274694.8A CN202110274694A CN112992323B CN 112992323 B CN112992323 B CN 112992323B CN 202110274694 A CN202110274694 A CN 202110274694A CN 112992323 B CN112992323 B CN 112992323B
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Abstract
The invention is suitable for the technical field of assisted reproduction, and discloses a sperm supply management system for a sperm bank, which comprises a reception module, a freezing module, a file management module and a supply module; the receiving module is used for inputting the identity information and the physical examination information of the first semen donation volunteers, identifying the identity of the second semen donation volunteers, encrypting the identity information of the semen donation volunteers for the first time and calculating the semen donation subsidy amount; the freezing module is used for encrypting the identity information of the donation volunteers after the first encryption for the second time, and recording semen analysis data of the donation volunteers and information of semen warehousing and ex-warehousing operation; the file management module is used for managing the electronic files of qualified donation volunteers and recording the feedback information of the sperm mechanism. The supply module is used for supplying the frozen semen to the semen using mechanism according to the application and the requirement of the semen using mechanism and the feedback information of the external semen supplying mechanism. The invention can automatically realize the management of supplying essence to the essence bank, does not need to consume too much manpower, and can greatly improve the working efficiency.
Description
Technical Field
The invention belongs to the technical field of assisted reproduction, and particularly relates to a sperm supplying management system for a sperm bank.
Background
The sperm bank is a mechanism for collecting, detecting, preserving and providing sperms by utilizing an ultralow temperature freezing technology, and the purposes of treating infertility, preventing genetic diseases, providing reproductive insurance and the like are achieved.
At present, the management of the sperm bank is usually manual management, but the manual management method is labor-consuming and low in working efficiency.
Disclosure of Invention
In view of this, the embodiment of the present invention provides a sperm library supply and management system, so as to solve the problems of manpower consumption and low working efficiency in the prior art.
The embodiment of the invention provides a sperm supply management system of a sperm bank, which comprises: the system comprises a reception module, a refrigeration module, a file management module and a supply module;
the receiving module is used for inputting the identity information and the physical examination information of the first donation spermatophore, identifying the identity of the second donation spermatophore, encrypting the identity information of the donation spermatophore for the first time and calculating donation spermatorrhea subsidy amount;
the freezing module is used for encrypting the identity information of the semen donation volunteers after the first encryption for the second time, and recording the data of semen analysis and freezing resuscitation experiments of the semen donation volunteers and the information of semen warehousing and ex-warehousing operation;
the file management module is used for carrying out classification management on the electronic files of qualified donation sperm volunteers and recording the use information of the external supply sperm, the pregnancy outcome information of the donation sperm acceptors and the birth information of offspring fed back by the sperm mechanism;
and the supply module is used for supplying the frozen semen to the semen using mechanism according to the application and the requirement of the semen using mechanism and the feedback information of the externally supplied semen.
Optionally, the supply module is further configured to determine the number of the reserved recipients, the number of the AIDs valid recipients, and the number of the IVF valid recipients corresponding to the semen of the semen donation volunteer, based on the number of the reserved recipients, the number of the AIDs valid recipients, and the number of the IVF valid recipients; wherein the semen of the semen donation volunteer can be externally supplied for the next time = 5-reserved number of recipients-number of AID effective recipients-number of IVF effective recipients;
the number of AID effective recipients comprises the number of pregnancies of the AID recipients, the number of AID recipients who use semen and do not feed back pregnancy information, and the number of semen which is externally used for AID and is not used;
the number of effective recipients of IVF includes the number of pregnancies of IVF recipients, the number of IVF recipients who have used semen and all embryos frozen without transfer, the number of IVF recipients who have used semen and have not fed back pregnancy information, the number of IVF recipients who have used semen and transferred embryos and have not been pregnant and have frozen embryos, and the number of semen fractions that have been ex-served for IVF and have not been used.
Optionally, the reception module is further configured to record the identity status of the semen donation volunteers as a screening period when the identity information of the semen donation volunteers is entered; after the physical examination information of the donation spermatozoa is all qualified, modifying the identity state of the donation spermatozoa into a donation period, and modifying the identity state of the donation spermatozoa into elimination when any one item of the physical examination information of the donation spermatozoa is unqualified; when the quantity of the semen donated by the semen donation volunteers is not less than a first preset semen quantity or the semen donation time is not less than a first preset number of days, modifying the identity state of the semen donation volunteers into a period to be supplied externally, and reminding workers of ending the donation period of the semen donation volunteers; starting timing when the semen donation volunteers in the external supply period donate semen for the last time, reminding workers to carry out HIV recheck on the semen donation volunteers after a second preset number of days, recording HIV recheck results, modifying the identity state of the qualified semen donation volunteers in the HIV recheck results into an external supply period, and modifying the identity state of the unqualified semen donation volunteers in the HIV recheck results into elimination; when the semen donation time of a semen donation volunteer is not less than a first preset number of days and the semen count frozen and stored by the semen donation volunteer is less than a second preset semen count, or when the semen donation volunteer does not carry out HIV recheck within a specified time, the identity state of the semen donation volunteer is modified to be eliminated;
the freezing module is also used for reminding the staff: storing the semen of the semen donation volunteers in the donation storage chamber, transferring the semen of the semen donation volunteers in the period of external supply from the donation storage chamber to the storage chamber for external supply, transferring the semen of the semen donation volunteers in the period of external supply from the storage chamber for external supply to the storage chamber for external supply, and destroying the rejected semen of the semen donation volunteers.
Optionally, the supply module is further configured to determine whether an abnormal condition occurs according to the usage information of the external supply semen, the pregnancy information of the semen supply recipient, and the birth information of the offspring, and label the information corresponding to the external supply semen as abnormal if the abnormal condition occurs.
Optionally, the abnormal condition includes at least one of the number of offspring birth defects corresponding to the same semen donating volunteer not less than a first preset number, the number of aborted recipients corresponding to the same semen donating volunteer not less than a second preset number, and preset abnormal information; the preset abnormal information is that the number of pregnant women in the recipients corresponding to the same sperm donation volunteer is 0, and the number of non-pregnant women is not less than a third preset number; the first preset quantity is smaller than the second preset quantity and smaller than the third preset quantity.
Optionally, the reception module is further configured to identify the identity of the volunteer donated again based on fingerprint recognition and image recognition.
Optionally, the reception module is further configured to generate a profile number according to the identity information of the semen donation volunteers when the identity information of the semen donation volunteers is encrypted for the first time;
and the freezing module is also used for generating a semen supply number according to the file number and the blood type of the semen donation volunteers when the identity information of the semen donation volunteers after the first encryption is encrypted for the second time.
Optionally, the supply module is further configured to record an expiration date of the agreement signed with the semen mechanism, check whether the expiration date is exceeded when the semen is supplied externally, and stop supplying the semen externally to the semen mechanism if the expiration date is exceeded.
Optionally, the freezing module is further configured to query a semen storage location, query a location usage of the semen storage tank, query usage of different batches of cryoprotectant solutions, and query semen analysis and a cryopreservation recovery experiment record.
Optionally, the sperm supply management system of the sperm bank further comprises a recruitment module and a supervisor module;
the recruitment module is used for checking the information input condition of the first sperm donation volunteers;
and the supervisor module is used for setting the authority of each module, analyzing and exporting the working record of each module so as to control the quality and update the sperm supply and management system of the sperm library.
Compared with the prior art, the embodiment of the invention has the following beneficial effects: the sperm supply management system of the sperm bank provided by the embodiment of the invention comprises: the system comprises a reception module, a freezing module, a file management module and a supply module; the receiving module is used for inputting the identity information and the physical examination information of the first donation spermatophore, identifying the identity of the second donation spermatophore, encrypting the identity information of the donation spermatophore for the first time and calculating donation spermatorrhea subsidy amount; the freezing module is used for encrypting the identity information of the donation spermatozoa subjected to the first encryption for the second time, and recording the data of semen analysis of the donation spermatozoa and the information of semen warehousing and ex-warehousing operation; the file management module is used for carrying out classification management on the electronic files of qualified donation sperm volunteers and recording the use information of the external supply sperm, the pregnancy outcome information of the donation sperm acceptors and the birth information of offspring fed back by the sperm mechanism; and the supply module is used for supplying the frozen semen to the semen using mechanism according to the application and the requirement of the semen using mechanism and the feedback information of the externally supplied semen. The sperm supply management system can automatically realize the sperm supply management of the sperm bank, does not need to consume too much manpower, and can greatly improve the working efficiency.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the embodiments or the prior art descriptions will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without inventive exercise.
Fig. 1 is a schematic diagram of a sperm bank for sperm management system according to an embodiment of the present invention.
Detailed Description
In the following description, for purposes of explanation and not limitation, specific details are set forth, such as particular system structures, techniques, etc. in order to provide a thorough understanding of the embodiments of the present application. It will be apparent, however, to one skilled in the art that the present application may be practiced in other embodiments that depart from these specific details. In other instances, detailed descriptions of well-known systems, devices, circuits, and methods are omitted so as not to obscure the description of the present application with unnecessary detail.
In order to illustrate the technical means of the present invention, the following description is given by way of specific examples.
Fig. 1 is a schematic diagram of a sperm library supply and management system according to an embodiment of the present invention, and for convenience of description, only the parts related to the embodiment of the present invention are shown.
As shown in fig. 1, the sperm bank sperm management system 10 may include: a reception module 11, a freezing module 12, a file management module 16 and a supply module 13;
the receiving module 11 is used for inputting the identity information and physical examination information of the first donation spermatophore, identifying the identity of the second donation spermatophore, encrypting the identity information of the donation spermatophore for the first time and calculating donation spermatorrhea subsidy amount;
the freezing module 12 is used for encrypting the identity information of the semen donation volunteers after the first encryption for the second time, and recording the data of semen analysis and freezing resuscitation experiments of the semen donation volunteers and the information of semen warehousing and ex-warehousing operations;
the file management module 16 is used for performing classified management on the electronic files of qualified donation sperm volunteers, and recording the use information of the external supply semen, the pregnancy outcome information of the donation sperm acceptors and the birth information of offspring fed back by the sperm mechanism;
and the supply module 13 is used for supplying the frozen semen to the semen using mechanism according to the application and the requirement of the semen using mechanism and the feedback information of the externally supplied semen.
The sperm cell management system 10 provided by the embodiment of the present invention is supported by hardware and software such as a server, a computer, and the like.
The physical examination information comprises basic physical examination information, blood information and a semen auxiliary examination result. The warehouse-in and warehouse-out operation can comprise warehouse-out, warehouse moving, warehouse entering, destroying and the like.
Specifically, the reception module 11 can be used for the first time of donation of semen volunteers ' identity information and the input of physical examination information, donate the discernment of semen volunteers ' identity again, donate the orderly arrangement of each item screening work, carry out the encryption for the first time to donate semen volunteers ' identity information, calculate donation of semen subsidy amount, filter the screening and the inquiry of not donating semen volunteers and each item information for a long time. After the receiving module 11 finishes inputting the relevant information, the system will automatically transfer part of the information to the freezing module 12 to perform the operations such as inputting the relevant information of the module. The reception module 11 is used for receiving personnel in departments to perform related operations.
The freezing module 12 is used for laboratory technicians to perform related operations, and specifically can be used for recording semen analysis data of semen donation volunteers, data of freezing resuscitation experiments, arrangement of semen auxiliary examination, information of operations such as warehousing, moving, ex-warehouse and destroying of frozen semen, and the like. In the semen donation process of the semen donation volunteers, the system can automatically display part of the information of the volunteers recorded by the reception module 11 in the module, and automatically complete the second encryption of the identity of the semen donation volunteers.
The file management module 16 is used for performing classified management on the electronic files of qualified donation spermatozoa, and specifically, the electronic files can be divided into externally-supplied spermatozoa and stoped-supplied spermatozoa according to different stages of the donation spermatozoa; the using condition of the external semen supplied by the semen mechanism (including analysis after semen resuscitation, a pregnancy assisting way of a semen supplier, a fertilization way and the like), the pregnancy ending information after the semen supplier (including the preservation of frozen embryos, clinical pregnancy, abortion and midterm induction), the birth information of offspring and the condition of 1 year after birth are recorded.
The supply module 13 is configured to deliver the external semen to the semen utilization mechanism (reproductive center), and select semen meeting the requirement for semen utilization according to various feedback information (including the information on the use of the external semen, the pregnancy outcome information of the semen-providing recipient, the birth information of offspring, and the like) of the used semen mechanism and the requirement for semen utilization of the semen utilization mechanism, for example, for IVF (In Vitro Fertilization) or AID (Artificial Insemination by Donor), blood type, ethnic group, and the like.
The sperm supply management system 10 provided by the embodiment of the present invention includes: a reception module 11, a freezing module 12, a file management module 16 and a supply module 13; the receiving module 11 is used for inputting the identity information and physical examination information of the first semen donation volunteers, identifying the identity of the second semen donation volunteers, encrypting the identity information of the first semen donation volunteers for the first time and calculating the semen donation subsidy amount; the freezing module 12 is used for encrypting the identity information of the semen donation volunteers after the first encryption for the second time, and recording the data of semen analysis and frozen resuscitation experiments of the semen donation volunteers and the information of semen warehousing-in and warehousing-out operations; the file management module 16 is used for performing classified management on the electronic files of qualified donation sperm volunteers, and recording the use information of the external supply semen, the pregnancy outcome information of the donation sperm acceptors and the birth information of offspring fed back by the sperm mechanism; and the supply module 13 is used for supplying the frozen semen to the semen using mechanism according to the application and the requirement of the semen using mechanism and the feedback information of the externally supplied semen. The sperm supply management system 10 can automatically realize the sperm supply management work of the sperm bank, does not need to consume too much manpower, and can greatly improve the work efficiency.
As an optional implementation, after the system performs secondary encryption on the identity information of the spermatogenic volunteers, DNA information specific to the genome part of the spermatogenic volunteers is obtained, and the DNA information is associated with the identity information after secondary encryption to form a data packet, where the data packet includes three parts: the first part is the identity information of the donated sperm volunteers after the secondary encryption; the second part is DNA information of the sperm-donating volunteers; the third part is information obtained by performing hash operation on the first part and the second part. The data packet is used as a first data packet in the chain, the second data packet in the chain is also three parts, wherein the first part and the second part are the same as the first data packet, except that the information is information of a second sperm-donating volunteer, and the third part is obtained by carrying out hash operation on the first part, the second part and the third part of a previous data packet in the second data packet. The data structure of the third data packet is the same as that of the second data packet, wherein the information is that of the third sperm-donating volunteer, and by analogy, one data packet is generated for each sperm-donating volunteer, so that the data packets of all the sperm-donating volunteers form a chain. The generation of the data packet is computed on a non-networked server. And after the chain is copied, uploading the chain to a plurality of cloud servers for storage on a device capable of being networked.
In the embodiment of the invention, the identity information of the semen donation volunteers is encrypted twice in the reception module 11 and the freezing module 12 respectively, so that not only can the identity privacy of the semen donation volunteers be protected and the identity information be prevented from being exposed, but also the possibility of associating the semen donation volunteers with the semen donation recipient information can be greatly reduced. Except for the user of the management module, any other module can not search all the information of the donated spermatozoa, and when the manager searches all the information of the donated spermatozoa, for example, the identity information of the donated spermatozoa is converted and associated, the manager can enter the donated spermatozoa only by inputting a double password.
In an embodiment of the present invention, the supply module 13 is further configured to determine the number of the reserved recipients, the number of the AIDs effective recipients, and the number of the IVF effective recipients corresponding to the semen of each semen donation volunteer, the number of the next available semen shares of the semen donation volunteer; wherein the semen of the semen donation volunteer can be externally supplied for the next time = 5-reserved number of recipients-number of AID effective recipients-number of IVF effective recipients.
Semen from one sperm donor volunteer only allowed up to 5 women to become pregnant. The system can automatically calculate the maximum external supply number of the next time according to the number of the external supplies of the semen of each semen donation volunteer, the use condition of the semen donation recipient, the pregnancy assisting mode, the conditions of whether clinical pregnancy, abortion, midterm induction of labor, whether frozen embryos exist and the like. Under the condition that 5 sperm donors are pregnant or frozen embryos are stored, the external supply of the semen of the sperm donor is automatically stopped. The system adopts digital logic to judge and calculate.
The number of the reserved recipients can be manually assigned, generally, the number of the reserved recipients can be 5 for volunteers with special characteristics, such as RH blood type negative and minority sperm donation volunteers, so that the sperm external supply of the sperm donation volunteers can be locked and reserved for the condition with specific requirements, and the external supply can be carried out after the number of the reserved recipients is modified.
The quantity of externally supplied semen is the most important and serious link in the work of the semen bank. The system can automatically calculate the number of the externally-supplied semen next time according to the number of the externally-supplied semen of each semen donation volunteer, the use condition fed back by the semen donation acceptors, the pregnancy condition, the information of whether the frozen embryo is stored and the like, and can avoid the occurrence of manual recording and calculation errors and excessive external supply.
The embodiment of the invention can reserve semen of a sperm donor with special characteristics, such as RH blood type negativity and minority nationality. In case of special requirement of the sperm mechanism (genital center), external supply is performed. Not only meets the requirements of specific people, but also avoids the ethical problem caused by the partial characteristic difference between the sperm donor and receptor.
In one embodiment of the invention, the number of AID valid recipients includes the number of pregnancies of the AID recipients, the number of AID recipients who have used semen and have not fed back pregnancy information, and the number of semen portions that have been used for AID and have not been used;
the number of effective recipients of IVF includes the number of pregnancies of IVF recipients, the number of IVF recipients who have used semen and all embryos frozen without transfer, the number of IVF recipients who have used semen and have not fed back pregnancy information, the number of IVF recipients who have used semen and transferred embryos and have not been pregnant and have frozen embryos, and the number of semen fractions that have been ex-served for IVF and have not been used.
Wherein the number of AID effective recipients is the sum of the number of pregnancies of the AID recipients, the number of AID recipients who use semen and do not feed back pregnancy information and the number of semen portions which are externally used for AID and are not used.
The number of effective recipients of the IVF is the sum of the number of pregnancies of the IVF recipients (including fresh period and freezing period, with and without frozen embryo), the number of IVF recipients who have used semen and all embryos frozen and not transplanted, the number of IVF recipients who have used semen and transplanted embryos and not pregnant and have frozen embryos, and the number of semen portions that have been used for IVF and not used.
In sperm-donating IVF, the number of people is counted if sperm-donating recipients have frozen embryos preserved, as gestation. The system tracks and records the number and the condition of the embryos fed back by the information until all the embryos are thawed, and the record of the sperm donor and the sperm acceptor can be calculated according to the pregnancy condition. And if the donor and the receiver have a plurality of periods of freshness and freezing, the last assignment is substituted into the formula for calculation. For example, after a fresh cycle transfer of embryos, no frozen embryos are stored and the system value is 1; after the pregnancy status is fed back as not pregnant, the system changes the assignment to 0. If the sperm donor and the sperm receiver have been born with offspring, the sperm donor and the sperm receiver are transplanted with the frozen embryo again and belong to the second fetus of the same woman, and after pregnancy, the system does not add the number of gestational people.
In an embodiment of the present invention, the reception module 11 is further configured to record the identity status of the semen donation volunteers as a screening period when the identity information of the semen donation volunteers is entered; after the physical examination information of the donation spermatozoa is all qualified, modifying the identity state of the donation spermatozoa into a donation period, and modifying the identity state of the donation spermatozoa into elimination when any one item of the physical examination information of the donation spermatozoa is unqualified; when the quantity of the semen donated by the semen donation volunteers is not less than a first preset semen quantity or the semen donation time is not less than a first preset number of days, modifying the identity state of the semen donation volunteers into a period to be supplied externally, and reminding workers of ending the donation period of the semen donation volunteers; starting timing when the sperm donation volunteers in the external supply period donate semen for the last time, reminding workers to carry out HIV recheck on the sperm donation volunteers after a second preset number of days, recording HIV recheck results, modifying the identity state of qualified sperm donation volunteers as the external supply period and modifying the identity state of unqualified sperm donation volunteers as the elimination period; when the semen donation time of a semen donation volunteer is not less than a first preset number of days and the semen count frozen and stored by the semen donation volunteer is less than a second preset semen count, or when the semen donation volunteer does not carry out HIV recheck within a specified time, the identity state of the semen donation volunteer is modified to be eliminated;
the refrigeration module 12 is also used for reminding the staff: storing the semen of the semen donation volunteers in the donation storage chamber, transferring the semen of the semen donation volunteers in the period of external supply from the donation storage chamber to the storage chamber for external supply, transferring the semen of the semen donation volunteers in the period of external supply from the storage chamber for external supply to the storage chamber for external supply, and destroying the rejected semen of the semen donation volunteers.
Specifically, the reception module 11 may record the identity status of the first semen donation volunteer as a screening period, the semen donation volunteer in the screening period records all the results in the reception module 11 after completing the archive establishment, the physical examination, the semen and blood examination in the screening period, if all the examination results are qualified, the screening period is automatically converted into the donation period, and if one is not qualified, the screening period is converted into the elimination period. Information regarding donated sperm volunteers for the donation period is automatically sent to the freezing module 12.
After the semen donation volunteers enter the donation period, the freezing module 12 will prompt the staff, specifically the laboratory personnel, to deposit the semen donated by the semen donation volunteers in the donation storage room.
Alternatively, the first preset number of semen may be 45 and the first preset number of days may be 180 days. That is, when the semen donated by the semen donation volunteer reaches 45 or the semen donation time (starting from the blood collection date of the screening period) reaches 180 days, the reception module 11 automatically converts the semen donation volunteer from the donation period to the non-donation period to end the semen donation, and displays the related information of the semen donation volunteer in the non-donation period in the reception module 11 and the freezing module 12. The reception module 11 prompts the end of the semen donation period, and corresponding staff reminds volunteers of the end of the semen donation period according to the prompt.
After receiving the information of the semen donation volunteers in the external supply period, the freezing module 12 prompts laboratory personnel to perform first bank transfer on the semen of the volunteers, and the semen is transferred from the donation storage room to the external supply storage room.
Wherein the second predetermined number of days may be 180 days. Namely, the reception module 11 starts to time at the time of last semen donation of the semen donation volunteer, prompts the staff to take blood from the semen donation volunteer for rechecking of projects such as HIV after 180 days, and records the rechecking result into the system after the rechecking result comes out. The reception module 11 automatically changes the identity state of the donation spermatozoa with qualified rechecking result from the external supply period to the external supply period, and changes the identity information of the donation spermatozoa with unqualified rechecking result from the external supply period to the elimination. Information regarding the availability of donated and rejected volunteers is automatically sent to the freezing module 12.
After receiving the information of the semen donation volunteers in the external supply period, the freezing module 12 prompts laboratory personnel to carry out second bank transfer, and the semen donation volunteers in the external supply period are transferred from the storage room to be externally supplied to the external supply storage room. The freezing module 12, upon receiving information from a rejected donated sperm volunteer, prompts laboratory personnel to destroy the semen of the rejected donated sperm volunteer.
Wherein, the information of the donated sperm volunteers in the period of external supply can be automatically sent into the supply module 13.
When the semen number frozen by the semen donation volunteer is too small to be supplied to the outside or the semen donation volunteer does not perform item review such as HIV in a specified time, the reception module 11 changes the identity state of the semen donation volunteer into elimination and displays related information in the freezing module 12.
The supply module 12 can be used for staff to check the semen information of all semen donation volunteers in the external supply period, and the external supply information is transferred to the freezing module 12 after the external supply operation is carried out on the semen in the external supply storage chamber according to the requirement. The freezing module 12 prompts the laboratory personnel to carry out the ex-warehouse operation according to the external supply information, and automatically transfers the semen ex-warehouse information to the file management module 16 for recording.
When the supply module 12 performs semen external supply operation, the number of external supply copies is automatically calculated according to different usage modes of the external supply semen. If the external semen is used for AID, 2 records are one copy; for external semen supply for IVF, 1 note was one.
The archive management module 16 can be used for archive management personnel to check all semen information which is supplied externally, after receiving the feedback information of the semen using mechanism, the semen information is recorded, and the feedback information related to the supply module 13 is automatically transferred to the supply module 13, so that the supply module 13 can automatically calculate the number of copies (counts) which can be supplied externally next time and display the copies in the supply module 13.
According to the embodiment of the invention, the judgment of the result and the calculation of the time can be automatically carried out according to the data input by each module, and the identity state of the semen donation volunteers can be automatically converted.
Optionally, in the reception module 11, calculating the donation-benefit amount may include:
and determining the semen donation subsidy amount according to the identity state of the semen donation volunteers. The status may include, among others, a screening period, a donation period, a pending alimentation period, an allocatable period, and a culling period.
Specifically, if the identity status of the semen donation volunteer is in the screening period, the amount of the semen donation subsidy of the semen donation volunteer is determined to be 100 yuan, that is, 100 yuan is subsidized in the screening period no matter whether the semen detection result is qualified or not.
And if the identity state of the semen donation volunteers is the donation period, determining the semen donation subsidy amount according to the semen detection result. Wherein, if the semen detection result is qualified, the semen donation supplement amount is 100 yuan, and if the semen detection result is unqualified, the semen donation supplement amount is 50 yuan.
And if the identity state of the semen donation volunteers is in the period of external supply, determining the semen donation subsidy amount according to the total semen count retained by the semen donation volunteers. The method comprises the following specific steps:
if the total semen count retained by the semen donation volunteer is less than the first preset total count and the system does not prompt to perform HIV review, the remaining subsidy is not issued any more, and the volunteer can be manually eliminated by the staff of the reception department corresponding to the reception module 11;
if the first preset total count is less than or equal to the total semen count retained by the semen donation volunteers and less than the second preset total count, determining the semen donation subsidy amount as a first preset semen donation subsidy amount;
if the second preset total count is less than or equal to the total semen count retained by the semen donation volunteers and less than the third preset total count, determining the semen donation subsidy amount as a second preset semen donation subsidy amount;
if the third preset total count is less than or equal to the semen total count retained by the semen donation volunteers and less than the fourth preset total count, determining the semen donation supplement amount as a third preset semen donation supplement amount;
and if the total semen count retained by the semen donation volunteers is more than or equal to 45, determining the semen donation auxiliary amount as a fourth preset semen donation auxiliary amount.
If the identity status of the donation volunteer is obsolete, no donation subsidy is calculated.
The first predetermined total count may be 5, the second predetermined total count may be 12, the third predetermined total count may be 30, and the fourth predetermined total count may be 45. The first preset donation essence supplementary amount may be 1000 yuan, the second preset donation essence supplementary amount may be 2000 yuan, the third preset donation essence supplementary amount may be 3500 yuan, and the fourth preset donation essence supplementary amount may be 5000 yuan. The values of the above-mentioned preset parameters can be adjusted according to the change of the work schedule.
In addition to donation of essence subsidies, the reward subsidy amount may be calculated according to the total duration of the donation period of the essence donator. Specifically, if the total duration of the donation period is less than or equal to a first preset number of days, determining the reward subsidy amount to be 1000 yuan; and if the total duration of the donation period is larger than the first preset number of days, determining that the reward subsidy amount is 0 yuan. Wherein the first preset number of days may be 180 days. The duration of the donation period is timed from the day of blood collection in the screening period.
In summary, the total subsidy amount of the donated spermatozoa = donated spermatozoa amount + reward amount.
After HIV review, the remaining subsidy amount to be earned = total subsidy amount-earned subsidy amount.
After the semen donation volunteers finish the semen retention in the donation period, the system can automatically calculate the total subsidy amount to be received by the volunteers, the donation semen subsidy amount already received in the screening period and the donation period and the residual subsidy amount according to the total number of the retained semen and the total duration of the donation period (timing is started from the blood collection date in the screening period), and the donation semen subsidy amount and the residual subsidy amount are all displayed in the reception module 11, so that the persons in the reception department corresponding to the reception module 11 can conveniently inform the donation volunteers in detail.
After the donation volunteer completes the HIV review, the system is entered, and the reception module 11 displays: the remaining subsidy amount may be collected.
Optionally, the reception module 11 may be further configured to record a total amount of subsidies released to the donation volunteer daily and a newly drawn reserve subsidy amount, and calculate a daily stock amount according to a yesterday stock amount, a daily total amount of subsidies released, and a daily newly drawn reserve subsidy amount. Namely, the daily stock amount = yesterday stock amount-total amount of subsidy dispensed on the day + amount of reserve subsidy newly retrieved on the day.
The reception module 11 can also be used to record the next semen donation time reserved by the semen donation volunteers in the donation period during each semen donation.
The reception module 11 can also be used for making statistics of the number of the people who donate sperm by reservation every day, and reminds the staff when the number of the people who donate sperm reaches the preset maximum number in reservation every day. The phenomenon that the appointment time of a plurality of volunteers is too concentrated and exceeds the reception capacity of the sperm bank can be effectively avoided.
The reception module 11 may also be used to display a list of donated spermatozoa reserved on the day, so that no-visited volunteers are followed by telephone calls after the daily work is finished.
The reception module 11 can also be used for automatic screening the information that the sperm in the same day detected unqualified donation period volunteer, generate EXCEL form, supply the staff of authorization to derive the system, so that the staff copies the back with the form, the automatic short message platform of sending outside the use system, inform the volunteer in the same day testing result and how to adjust self state, when improving personnel work efficiency, the qualification probability that the sperm detected when also having improved this volunteer donated the sperm next time, also avoided communicating the system directly with the internet, the information security hidden danger of bringing.
The reception module 11 may also be used to automatically screen information of recent (e.g., last 15 or 30 days) non-spermatogenic volunteers to facilitate screening and management of inactive volunteers.
In an embodiment of the present invention, the supplying module 13 is further configured to determine whether an abnormal condition occurs according to the usage information of the external supply semen, the pregnancy outcome information of the semen supplier and the birth information of the offspring, and if the abnormal condition occurs, label the information corresponding to the external supply semen with an abnormality.
The information corresponding to the semen supply outside the semen supply is marked to be abnormal, wherein the information can be automatically changed in color, for example, the information is normally black, and is changed into red when an abnormal condition occurs, and the like.
The embodiment of the invention can judge according to fertilization situation, offspring birth situation and the like of the sperm donor and the sperm acceptor fed back by the sperm mechanism, and when abnormal situations occur, the sperm supply information of the sperm donor automatically changes color to prompt cautious external supply.
In an embodiment of the present invention, the abnormal condition includes at least one of the number of birth defects of offspring corresponding to the same semen donating volunteer not less than a first preset number, the number of abortion of recipients corresponding to the same semen donating volunteer not less than a second preset number, and preset abnormal information; the preset abnormal information is that the number of pregnant people in recipients corresponding to the same sperm-donating volunteers is 0, and the number of non-pregnant people is not less than a third preset number; the first preset quantity is smaller than the second preset quantity and smaller than the third preset quantity.
The abnormal conditions include: the information of the offspring is fed back to the birth defect, and a plurality of women are not pregnant or aborted after using the semen of the same semen donor. The system also adopts digital logic to judge and calculate.
Alternatively, the first predetermined number may be 1, the second predetermined number may be 3, and the third predetermined number may be 10.
The embodiment of the invention can carry out the quality control before the next external supply according to the feedback information of the external supply semen. When birth defects appear in the information feedback of the offspring, multiple women are not pregnant or aborted after using the semen of the same semen donation volunteer, and the system automatically changes the color of the semen information of the semen donation to prompt the next prudent external supply.
In one embodiment of the present invention, the reception module 11 is further configured to identify the identity of the re-donated volunteers based on fingerprint recognition and image recognition.
Specifically, when the identity of the volunteer donating sperm again is identified, the fingerprint and the photo of the volunteer donating sperm can be collected and compared with the fingerprint information and the photo information of the volunteer prestored in the system, and if the fingerprint and the photo are the same, the identity of the volunteer is successfully identified. And the double check can avoid the possibility of repeatedly donating essence by substituting names or borrowing other identity cards in the midway.
In an embodiment of the present invention, the reception module 11 is further configured to generate a profile number according to the identity information of the semen donation volunteers when the identity information of the semen donation volunteers is encrypted for the first time;
the freezing module 12 is further configured to generate a semen donation number according to the profile number and the blood type of the semen donation volunteers when the identity information of the semen donation volunteers after the first encryption is encrypted for the second time.
The file number of donation spermatophore is dispatched by the system is automatic in succession, supplies the essence number according to donation spermatophore's blood type, and automatic in succession is dispatched, not only can stop the possibility that artifical group number made mistakes, has more mainly accomplished the restriction of each module authority.
In one embodiment of the present invention, the supply module 13 is further configured to record the expiration date of the agreement with the semen mechanism, check whether the expiration date is exceeded when semen is supplied externally, and stop the semen supply externally to the semen mechanism if the expiration date is exceeded.
In an embodiment of the present invention, the freezing module 12 is further configured to query a semen storage location, query a location usage of a semen storage tank, query usage of different lot numbers of freezing protection solutions, and query semen analysis and freezing resuscitation experiment records.
Optionally, the freezing module 12 may also perform query on the semen warehousing, moving, leaving, and destroying records.
The freezing module 12 can also realize the query of the storage location of the frozen semen, the query of the use condition of the location of the frozen semen storage tank, the query of each experimental record, the maintenance of the use batch number of the freezing protection liquid, and the like. The freezing module 12 can inquire the service time and the service test record of the freezing protection liquid of different batches, and is convenient for the quality control and analysis of the freezing protection liquid of different batches.
In one embodiment of the present invention, the sperm library management system 10 further comprises a recruitment module 14 and a supervisor module 15;
the recruitment module 14 is used for checking the information input condition of the first sperm donation volunteers;
and the supervisor module 15 is used for setting the authority of each module, analyzing and exporting the working record of each module, and updating the sperm library sperm supply management system 10.
The recruitment module 14 is used for the recruitment department personnel to check the situation of the recruited new donated volunteers, and to record the situation of the system after the initial screening.
And the supervisor module 15 is used for setting and modifying the authority of each department module by a person in charge (manager) of the sperm bank department, analyzing and exporting the working records of each module to perform quality control, updating and maintaining the system and the like.
Optionally, the refrigeration module 12 is connected to the reception module 11 and the supply module 13, the recruitment module 14 is connected to the reception module 11, the archive management module 16 is connected to the reception module 11 and the supply module 13, and the supervisor module 15 is connected to the reception module 11, the supply module 13, the refrigeration module 12, the archive management module 16 and the recruitment module 14.
And the information of each module is exported, so that the rapid analysis and statistics of various data are facilitated, and the quality analysis and control are carried out.
In the embodiment of the invention, after the important information of each module is input by one person, the important information is checked and stored by a second person. The information can not be changed later, the accuracy of the information can be improved, and the possibility of single-person tampering is avoided.
The sperm library provided by the embodiment of the invention can be used by the sperm management system 10 to protect data security in various ways, and is convenient for recovering data to use when needed.
Specifically, the supervisor module 15 may also be configured to lock and store information newly entered on the day at midnight 0 every day, and the information cannot be changed later, so as to prevent the previous data information from being affected by a later-stage misoperation.
The supervisor module 15 may also be configured to save the daily final data with the date of the day as the file name, and automatically save the daily data file for the last 7 days. If there is a malfunction on a certain day in the last 7 days, the data can be restored to the state before the malfunction.
The supervisor module 15 can also be used for automatically backing up data to the standby hard disk in a preset time, so that the data loss caused by the damage of a single hard disk can be prevented; the spare hard disk is stored in a place outside the server by the workers, so that data damage caused by accidents of the machine room is prevented, and the data safety is further enhanced. Of course, the backup can also be performed manually by the staff.
The embodiment of the invention automatically transmits part of relevant information in the working process through information correlation among the modules, can realize authority setting of the modules, enhances the confidentiality of personal information of the donation spermatozoa in the sperm bank, and can further avoid the possibility of leakage of the whole set of information of the donation spermatozoa.
The sperm bank sperm supply management system 10 provided by the embodiment of the invention can realize the functions of identification of sperm donation volunteers, establishment of information and files, sperm donation flow arrangement, storage management of frozen semen, sperm feedback information management, sperm supply management outside the sperm supply and the like through each module, organically connect the work of each work department, transmit data among each department in real time by using the information, save the labor cost and improve the work efficiency.
It is obvious to those skilled in the art that, for convenience and simplicity of description, the foregoing division of the functional units and modules is merely used as an example, and in practical applications, the foregoing function distribution may be performed by different functional units and modules as needed, that is, the sperm library is provided for the internal structure of the sperm management system and divided into different functional units or modules, so as to perform all or part of the above-described functions. Each functional unit and module in the embodiments may be integrated in one processing unit, or each unit may exist alone physically, or two or more units are integrated in one unit, and the integrated unit may be implemented in a form of hardware, or in a form of software functional unit. In addition, specific names of the functional units and modules are only for convenience of distinguishing from each other, and are not used for limiting the protection scope of the present application. For the specific working processes of the units and modules in the above-mentioned apparatus, reference may be made to the corresponding processes in the foregoing method embodiments, which are not described herein again.
In the above embodiments, the descriptions of the respective embodiments have respective emphasis, and reference may be made to the related descriptions of other embodiments for parts that are not described or illustrated in a certain embodiment.
Those of ordinary skill in the art will appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware or combinations of computer software and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the technical solution. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present application.
In the embodiments provided in the present application, it should be understood that the disclosed sperm library for the sperm management system and method may be implemented in other ways. For example, the above-described example of a sperm library for a sperm management system is merely illustrative, and for example, the division of the modules or units is only one logical division, and there may be other divisions in an actual implementation, for example, multiple units or components may be combined or integrated into another system, or some features may be omitted, or not implemented. In addition, the shown or discussed mutual coupling or direct coupling or communication connection may be an indirect coupling or communication connection through some interfaces, devices or units, and may be in an electrical, mechanical or other form.
The units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the solution of the embodiment.
In addition, functional units in the embodiments of the present application may be integrated into one processing unit, or each unit may exist alone physically, or two or more units are integrated into one unit. The integrated unit can be realized in a form of hardware, and can also be realized in a form of a software functional unit.
The integrated module/unit, if implemented in the form of a software functional unit and sold or used as a stand-alone product, may be stored in a computer readable storage medium. Based on such understanding, all or part of the flow in the method of the embodiments described above can be realized by a computer program, which can be stored in a computer-readable storage medium and can realize the steps of the embodiments of the methods described above when the computer program is executed by a processor. Wherein the computer program comprises computer program code, which may be in the form of source code, object code, an executable file or some intermediate form, etc. The computer-readable medium may include: any entity or device capable of carrying the computer program code, recording medium, U.S. disk, removable hard disk, magnetic diskette, optical disk, computer Memory, read-Only Memory (ROM), random Access Memory (RAM), electrical carrier wave signal, telecommunications signal, and software distribution medium, etc. It should be noted that the computer readable medium may contain other components which may be suitably increased or decreased as required by legislation and patent practice in jurisdictions, for example, in some jurisdictions, computer readable media which may not include electrical carrier signals and telecommunications signals in accordance with legislation and patent practice.
The above-mentioned embodiments are only used for illustrating the technical solutions of the present application, and not for limiting the same; although the present application has been described in detail with reference to the foregoing embodiments, it should be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not substantially depart from the spirit and scope of the embodiments of the present application and are intended to be included within the scope of the present application.
Claims (9)
1. A sperm bank sperm supply management system, comprising: the system comprises a reception module, a refrigeration module, a file management module and a supply module;
the receiving module is used for inputting the identity information and physical examination information of the first donation spermatophore, identifying the identity of the second donation spermatophore, encrypting the identity information of the donation spermatophore for the first time and calculating donation spermatorrhea subsidy amount;
the freezing module is used for encrypting the identity information of the semen donation volunteers after the first encryption for the second time, and recording the data of semen analysis and freezing resuscitation experiments of the semen donation volunteers and the information of semen warehousing and ex-warehousing operation;
the file management module is used for carrying out classification management on the electronic files of qualified sperm donation volunteers and recording the use information of external supply semen, the pregnancy outcome information of sperm donors and offspring birth information fed back by the sperm mechanism;
the supply module is used for supplying frozen semen to the semen using mechanism according to the application and the requirement of the semen using mechanism and the feedback information of the externally supplied semen;
the reception module is further used for recording the identity state of the semen donation volunteers as a screening period when the identity information of the semen donation volunteers is input; after the physical examination information of the sperm-donating volunteers is completely qualified, modifying the identity state of the sperm-donating volunteers into a donation period, and when any item in the physical examination information of the sperm-donating volunteers is unqualified, modifying the identity state of the sperm-donating volunteers into elimination; when the quantity of the semen donated by the semen donation volunteers is not less than a first preset semen quantity or the semen donation time is not less than a first preset number of days, modifying the identity state of the semen donation volunteers into a period to be supplied externally, and reminding workers of ending the donation period of the semen donation volunteers; starting timing when the semen donation volunteers in the external supply period donate semen for the last time, reminding workers to carry out HIV recheck on the semen donation volunteers after a second preset number of days, recording HIV recheck results, modifying the identity state of the qualified semen donation volunteers in the HIV recheck results into an external supply period, and modifying the identity state of the unqualified semen donation volunteers in the HIV recheck results into elimination; when the semen donation time of a semen donation volunteer is not less than a first preset number of days and the semen count frozen and stored by the semen donation volunteer is less than a second preset semen count, or when the semen donation volunteer does not carry out HIV recheck within a specified time, the identity state of the semen donation volunteer is modified to be eliminated;
the freezing module is also used for reminding workers: storing the semen of the donation spermatophore in a donation storage chamber, transferring the semen of the donation spermatophore to be in an external supply period from the donation storage chamber to the storage chamber to be in the external supply period, transferring the semen of the donation spermatophore to be in the external supply period from the storage chamber to be in the external supply storage chamber, and destroying the rejected semen of the donation spermatophore.
2. The sperm bank sperm supply management system of claim 1, wherein the supply module is further configured to determine the next number of available semen portions of the sperm donor volunteers based on the number of reserved recipients, the number of valid recipients for AID, and the number of valid recipients for IVF corresponding to the sperm donor volunteers; wherein, the semen of the semen donation volunteer can be externally supplied for the next time = 5-the number of reserved recipients-the number of AID effective recipients-the number of IVF effective recipients;
the number of AID effective recipients comprises the number of pregnancies of the AID recipients, the number of AID recipients who use semen and do not feed back pregnancy information, and the number of semen which is externally used for AID and is not used;
the effective recipients of the IVF include the number of pregnancies of the IVF recipients, the number of IVF recipients who have used semen and all embryos frozen and not transplanted, the number of IVF recipients who have used semen and not fed back pregnancy information, the number of IVF recipients who have used semen and transplanted embryos and not pregnant and have frozen embryos, and the number of semen portions that have been used for IVF and not used.
3. The sperm bank sperm supply management system of claim 1, wherein the supply module is further configured to determine whether an abnormal condition occurs according to the usage information of the external supply semen, the pregnancy outcome information of the sperm supply recipient, and the birth information of the offspring, and if an abnormal condition occurs, label the information corresponding to the external supply semen as abnormal.
4. The sperm bank sperm supply management system of claim 3, wherein the abnormal condition comprises at least one of a number of offspring birth defects corresponding to the same sperm-donating volunteer not less than a first preset number, a number of abortion of recipients corresponding to the same sperm-donating volunteer not less than a second preset number, and preset abnormal information; the preset abnormal information is that the number of pregnant women in the recipients corresponding to the same sperm donation volunteer is 0, and the number of non-pregnant women is not less than a third preset number; the first preset quantity is smaller than the second preset quantity and smaller than the third preset quantity.
5. The sperm bank sperm supply management system of claim 1 wherein the hospitality module is further configured to identify the identity of the re-donated sperm volunteers based on a combination of fingerprint recognition and image recognition.
6. The sperm bank sperm supply management system of claim 1, wherein the reception module is further configured to generate a profile number according to the identity information of the donated sperm volunteers when the identity information of the donated sperm volunteers is encrypted for the first time;
and the freezing module is also used for generating a semen donation number according to the profile number and the blood type of the semen donation volunteers when the identity information of the semen donation volunteers subjected to the first encryption is encrypted for the second time.
7. The sperm bank sperm supply management system of claim 1, wherein the supply module is further configured to record an expiration date of an agreement with the sperm utilization mechanism, check whether the expiration date is exceeded when semen is supplied externally, and stop the semen supply to the sperm utilization mechanism if the expiration date is exceeded.
8. The sperm bank sperm supply management system of claim 1, wherein the freezing module is further configured to query a sperm storage location, query a location usage of a sperm storage tank, query usage of different lot numbers of cryoprotectants, and query sperm analysis and cryo-resuscitation experimental records.
9. The sperm bank sperm management system of any one of claims 1 to 8 further comprising a recruitment module and a supervisor module;
the recruitment module is used for checking the information input condition of the first sperm donation volunteers;
and the supervisor module is used for setting and analyzing the authority of each module and exporting the working record of each module so as to control the quality and update the sperm library for the sperm management system.
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| CN112270783A (en) * | 2020-09-27 | 2021-01-26 | 四川大学华西第二医院 | Sperm bank identity verification and process management system based on three-dimensional face recognition technology |
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