CN112973562A

CN112973562A - Preparation process of traditional Chinese medicine compound for reducing livestock and poultry vaccine reaction

Info

Publication number: CN112973562A
Application number: CN202110315993.1A
Authority: CN
Inventors: 方文军; 岳耀辉; 李希臣; 郭新鹏; 钟文才; 胡春娥
Original assignee: Gaomi Yuyang Breeding Co ltd; Weifang Yuyang Pharmaceutical Co ltd
Current assignee: Gaomi Yuyang Breeding Co ltd; Weifang Yuyang Pharmaceutical Co ltd
Priority date: 2021-03-24
Filing date: 2021-03-24
Publication date: 2021-06-18

Abstract

The invention relates to a preparation process of a traditional Chinese medicine compound for reducing livestock and poultry vaccine reaction, which comprises the following steps: step one, adding traditional Chinese medicine raw materials into a pharmaceutical tank through a first feeding hole, adding traditional Chinese medicine auxiliary materials into the pharmaceutical tank through a second feeding hole, adding water into the pharmaceutical tank through a liquid inlet, and mixing by using a stirrer to form a traditional Chinese medicine preparation mixture; step two, when the device is used for preparing the traditional Chinese medicine liquid, a first control valve is opened to enable the traditional Chinese medicine preparation mixture to flow into a first storage tank; step three, when the traditional Chinese medicine ointment is prepared, opening a second control valve to enable the traditional Chinese medicine preparation mixture to flow into a second storage tank; and step four, when the traditional Chinese medicine preparation mixture is used for preparing traditional Chinese medicine particles, opening a third control valve to enable the traditional Chinese medicine preparation mixture to flow into a third storage tank. Therefore, the concentration and viscosity of the raw materials in the preparation process can be accurately controlled, the preparation efficiency is improved, and the traditional Chinese medicine particles, the traditional Chinese medicine ointment and the traditional Chinese medicine liquid can be prepared by the same equipment.

Description

Preparation process of traditional Chinese medicine compound for reducing livestock and poultry vaccine reaction

Technical Field

The invention relates to the field of a preparation process of a traditional Chinese medicine compound, in particular to a preparation process of a traditional Chinese medicine compound for reducing livestock and poultry vaccine reaction.

Background

In recent years, with the rapid development of economy in China, the living standard of the masses is continuously improved, the output rate of animal husbandry is doubled, in order to ensure the safety of livestock and poultry, the livestock and poultry need to be injected with vaccines regularly, inevitably, the livestock and poultry can suffer from lassitude, anorexia, body temperature rise, vomiting and serious death possibly after the vaccines are injected, more and more traditional Chinese medicine compounds are used for reducing the vaccine reaction of the livestock and poultry, and how to utilize the existing traditional Chinese medicine compounds to safely and completely prepare medicines becomes a problem worthy of research.

At present, the existing process is used for preparing a traditional Chinese medicine compound, but the concentration and the viscosity of raw materials in the preparation process cannot be accurately controlled, and traditional Chinese medicine particles, traditional Chinese medicine ointment and traditional Chinese medicine liquid cannot be prepared by the same equipment.

Disclosure of Invention

Therefore, the invention provides a preparation process of a traditional Chinese medicine compound for reducing livestock and poultry vaccine reaction, which can accurately control the concentration and viscosity of raw materials in the preparation process, improve the preparation efficiency, and can prepare traditional Chinese medicine granules, traditional Chinese medicine ointment and traditional Chinese medicine liquid through the same equipment.

In order to achieve the above object, the present invention provides a process for preparing a Chinese herbal compound for reducing livestock and poultry vaccine reaction, comprising:

adding traditional Chinese medicine raw materials into a pharmaceutical tank through a first feeding hole, adding traditional Chinese medicine auxiliary materials into the pharmaceutical tank through a second feeding hole, adding water into the pharmaceutical tank through a liquid inlet, and mixing the traditional Chinese medicine raw materials, the traditional Chinese medicine auxiliary materials and the water by using a stirrer to form a traditional Chinese medicine preparation mixture; in the stirring process, a central control module controls a temperature measuring instrument to measure the temperature of the traditional Chinese medicine preparation mixture and compare the measured real-time temperature with the preset temperature of the traditional Chinese medicine preparation mixture, when the central control module judges that the comparison result does not meet a first preset condition, the central control module calculates a temperature difference adjusting coefficient, when the calculation is finished, the central control module calculates a temperature difference value by combining the temperature adjusting coefficient and compares the temperature difference value with the parameters in a preset temperature difference value matrix delta H0, and the central control module controls a temperature adjusting valve to adjust the temperature in the pharmaceutical tank according to the comparison result;

when the central control module judges that the comparison result meets a first preset condition, the central control module controls a concentration measuring instrument to measure the concentration of the traditional Chinese medicine preparation mixture and compares the measured real-time concentration with the preset concentration of the traditional Chinese medicine preparation mixture, and the central control module judges according to the comparison result that a viscosity measuring instrument is controlled to measure the viscosity of the traditional Chinese medicine preparation mixture or controls a first feed port to add traditional Chinese medicine raw materials or controls a second feed port to add traditional Chinese medicine auxiliary materials;

when the central control module controls the first feed port to add the traditional Chinese medicine raw materials, the central control module calculates a concentration difference value and matches the concentration difference value with the parameter in a preset concentration difference value interval matrix delta Sa0 to determine the amount of the traditional Chinese medicine raw materials to be added, and when the determination is finished, the central control module controls the first feed port to add the traditional Chinese medicine raw materials;

when the central control module controls the second feed port to add the traditional Chinese medicine auxiliary materials, the central control module controls the pressure measuring instrument to measure the pressure in the pharmaceutical tank and compares the measured pressure with the parameters in the preset pharmaceutical tank pressure matrix N0 to determine the amount of the traditional Chinese medicine auxiliary materials to be added, and when the determination is finished, the central control module controls the second feed port to add the traditional Chinese medicine auxiliary materials;

when the central control module controls the viscosity measuring instrument to measure the viscosity of the traditional Chinese medicine preparation mixture, the central control module compares the measured real-time viscosity with parameters in a preset traditional Chinese medicine preparation mixture viscosity matrix eta 0, and when the central control module judges that the comparison result meets a second preset condition, the central control module judges that the traditional Chinese medicine preparation mixture can be used for preparing traditional Chinese medicine liquid or traditional Chinese medicine ointment or traditional Chinese medicine particles;

when the central control module judges that the comparison result meets a second preset condition, the central control module controls the liquid inlet to add water or controls the temperature regulating valve to regulate the temperature;

step two, when the central control module judges that the traditional Chinese medicine preparation mixture is used for preparing traditional Chinese medicine liquid, a first control valve is opened to enable the traditional Chinese medicine preparation mixture to flow into a first storage tank;

step three, when the central control module judges that the traditional Chinese medicine preparation mixture is used for preparing traditional Chinese medicine ointment, opening a second control valve to enable the traditional Chinese medicine preparation mixture to flow into a second storage tank;

step four, when the central control module judges that the traditional Chinese medicine preparation mixture is used for preparing traditional Chinese medicine particles, a third control valve is opened to enable the traditional Chinese medicine preparation mixture to flow into a third storage tank;

the central control module is further provided with a preset temperature difference matrix delta H0 (delta H1, delta H2 and delta H3), wherein delta H1 represents a first preset temperature difference value, delta H2 represents a second preset temperature difference value, delta H3 represents a third preset temperature difference value, and delta H1 is smaller than delta H2 and smaller than delta H3;

the central control module is further provided with a preset temperature regulating quantity matrix Q0(Q1, Q2, Q3 and Q4), wherein Q1 represents a first preset temperature regulating quantity, Q2 represents a second preset temperature regulating quantity, Q3 represents a third preset temperature regulating quantity, and Q4 represents a fourth preset temperature regulating quantity;

when the central control module judges that the comparison result meets a first preset condition, the central control module calculates a temperature adjusting coefficient sigma, and when the calculation is completed, the central control module calculates a temperature difference value delta H by combining sigma and compares the temperature difference value delta H with parameters in a preset temperature difference value matrix delta H0:

if the delta H is less than the delta H1, the central control module controls the temperature regulating valve to increase the temperature of Q1 quantity;

if the delta H is not more than delta H1 and less than delta H2, the central control module controls the temperature of the temperature regulating valve to increase the temperature of Q2;

if the delta H is not more than delta H2 and less than delta H3, the central control module controls the temperature of the temperature regulating valve to increase the temperature of Q3;

if the delta H is not less than or equal to the delta H3, the central control module controls the temperature regulating valve to raise the temperature of the Q4 amount;

the calculation formula of the temperature adjustment coefficient sigma is as follows,

σ＝(H/H0)×((H0+H)/(H0+H))；

the calculation formula of the temperature difference Δ H is as follows,

△H＝(H0-H)×σ；

in the formula, H0 represents the preset temperature of the mixture prepared from the traditional Chinese medicines, and H represents the real-time temperature of the mixture prepared from the traditional Chinese medicines.

Further, in the stirring process, the real-time temperature of the traditional Chinese medicine preparation mixture measured by the temperature measuring instrument is H, meanwhile, the central control module is further provided with a preset traditional Chinese medicine preparation mixture temperature H0, and in the stirring process, the central control module compares H with H0:

if H is larger than or equal to H0, the central control module judges that the comparison result meets a first preset condition;

and if H is less than H0, the central control module judges that the comparison result does not meet the first preset condition.

Further, the central control module is also provided with a preset concentration S0 of the traditional Chinese medicine preparation mixture;

when the central control module judges that the price comparison result meets a first preset condition, the central control module controls a concentration measuring instrument to measure the concentration of the traditional Chinese medicine preparation mixture and compares the measured real-time concentration S of the traditional Chinese medicine preparation mixture with S0:

if S is less than S0, the central control module controls the first feed inlet to add the traditional Chinese medicine raw materials;

if S is S0, the central control module controls a viscosity measuring instrument to measure the viscosity of the traditional Chinese medicine preparation mixture;

if S is more than S0, the central control module controls the first feed inlet to add the traditional Chinese medicine raw materials.

Further, the central control module is further provided with a preset concentration difference interval matrix Δ Sa0(Δ Sa1, Δ Sa2, Δ Sa3, Δ Sa4), wherein Δ Sa1 represents a first difference interval of preset concentration, Δ Sa2 represents a second difference interval of preset concentration, Δ Sa3 represents a third difference interval of preset concentration, and Δ Sa4 represents a fourth difference interval of preset concentration, and numerical ranges of the intervals are not overlapped;

the central control module is also provided with a preset traditional Chinese medicine raw material adding matrix ma0(ma1, ma2, ma3 and ma4), wherein ma1 represents a first preset traditional Chinese medicine raw material adding amount, ma2 represents a second preset traditional Chinese medicine raw material adding amount, ma3 represents a third preset traditional Chinese medicine raw material adding amount, and ma4 represents a fourth preset traditional Chinese medicine raw material adding amount;

when the central control module controls the first feed inlet to add the traditional Chinese medicine raw materials, the central control module calculates a concentration difference value delta Sa and matches the concentration difference value delta Sa with parameters in a preset concentration difference value interval matrix delta Sa 0:

if the delta Sa is within the range of delta Sai, the central control module controls the first feed inlet to add mai amounts of traditional Chinese medicine raw materials, and i is 1,2,3 and 4;

the concentration difference Δ Sa is calculated as follows:

△Sa＝(S0-S)×β；

wherein β represents a concentration adjustment coefficient, and β is S0/S.

Further, the central control module is further provided with a preset pharmaceutical tank pressure matrix N0(N1, N2 and N3), wherein N1 represents a preset pharmaceutical tank first pressure, N2 represents a preset pharmaceutical tank second pressure, N3 represents a preset pharmaceutical tank third pressure, and N1 < N2 < N3;

the central control module is further provided with a preset traditional Chinese medicine auxiliary material adding matrix mb0(mb1, mb2, mb3 and mb4), wherein mb1 represents a first preset traditional Chinese medicine auxiliary material adding amount, mb2 represents a second preset traditional Chinese medicine auxiliary material adding amount, mb3 represents a third preset traditional Chinese medicine auxiliary material adding amount, and mb4 represents a fourth preset traditional Chinese medicine auxiliary material adding amount;

when the central control module controls the second feed port to add the traditional Chinese medicine auxiliary materials, the central control module controls the pressure measuring instrument to measure the pressure in the pharmaceutical tank and compares the measured pressure N with the parameters in a preset pharmaceutical tank pressure matrix N0:

if N is less than N1, the central control module controls the second feed inlet to add the traditional Chinese medicine auxiliary materials with the amount of mb 1;

if N is more than or equal to N1 and less than N2, the central control module controls the second feed inlet to add the traditional Chinese medicine auxiliary materials with the amount of mb 2;

if N is more than or equal to N2 and less than N3, the central control module controls the second feed inlet to add the traditional Chinese medicine auxiliary materials with the amount of mb 3;

if N is larger than or equal to N3, the central control module controls the second feed inlet to add the traditional Chinese medicine auxiliary materials with the amount of mb 4.

Further, the central control module is also provided with a preset viscosity matrix eta 0 (eta min, eta max) of the traditional Chinese medicine preparation mixture, wherein eta min represents the lowest viscosity of the preset traditional Chinese medicine preparation mixture, eta max represents the highest viscosity of the preset traditional Chinese medicine preparation mixture, and eta min is less than eta max;

when the central control module controls the viscosity measuring instrument to measure the viscosity of the traditional Chinese medicine preparation mixture, the central control module compares the measured real-time viscosity eta with the parameters in a preset traditional Chinese medicine preparation mixture viscosity matrix eta 0:

if eta is not less than eta min and not more than eta max, the central control module judges that the comparison result meets a second preset condition, and the traditional Chinese medicine preparation mixture can be used for preparing traditional Chinese medicine liquid or traditional Chinese medicine ointment or traditional Chinese medicine particles;

if eta is less than eta min, the central control module judges that the comparison result does not accord with a second preset condition and controls the temperature regulating valve to regulate the temperature;

if eta is larger than eta max, the central control module judges that the comparison result does not accord with a second preset condition and controls the liquid inlet to be added with water.

Further, the central control module is further provided with a density matrix rho 0 (rho 1, rho 2, rho 3) of the preset traditional Chinese medicine preparation mixture, wherein rho 1 represents a first density of the preset traditional Chinese medicine preparation mixture, rho 2 represents a second density of the preset traditional Chinese medicine preparation mixture, rho 3 represents a third density of the preset traditional Chinese medicine preparation mixture, and rho 1 is greater than rho 2 and is greater than rho 3;

when the central control module judges that the comparison result meets a second preset condition, the central control module controls a density measuring instrument to measure the density of the traditional Chinese medicine preparation mixture and compares the measured real-time density rho of the traditional Chinese medicine preparation mixture with the parameters in a preset traditional Chinese medicine preparation mixture density matrix rho 0:

if rho is rho 1, the central control module judges that the traditional Chinese medicine preparation mixture can be used for preparing traditional Chinese medicine liquid;

if rho is rho 2, the central control module judges that the traditional Chinese medicine preparation mixture can be used for preparing traditional Chinese medicine ointment;

if rho is rho 3, the central control module judges that the traditional Chinese medicine preparation mixture can be used for preparing traditional Chinese medicine particles.

Further, the central control module is further provided with a preset first viscosity difference matrix Δ η a0(Δ η a1, Δ η a2, Δ η a3), wherein Δ η a1 represents a preset first viscosity first difference, Δ η a2 represents a preset first viscosity second difference, Δ η a3 represents a preset first viscosity third difference, and Δ η a1 < Δη a2 < Δη a 3;

the central control module is further provided with a preset water adding amount matrix mc0(mc1, mc2, mc3 and mc4), wherein mc1 represents a first preset water adding amount, mc2 represents a second preset water adding amount, mc3 represents a third preset water adding amount, and mc4 represents a fourth preset water adding amount;

when the central control module judges that the comparison result does not accord with a second preset condition and controls the liquid inlet to add water, the central control module calculates a first viscosity difference value delta eta a, and when the calculation is completed, the central control module compares the first viscosity difference value delta eta a with parameters in a preset first viscosity difference matrix delta eta a 0:

if the delta eta a is less than the delta eta a1, the central control module controls the liquid inlet to add water with the amount of mc 1;

if the delta eta a is not more than delta eta a1 and is less than delta eta a2, the central control module controls the liquid inlet to be added with water with the amount of mc 2;

if the delta eta a is not more than delta eta a2 and is less than delta eta a3, the central control module controls the liquid inlet to be added with water with the amount of mc 3;

if the delta eta a is more than or equal to the delta eta a3, the central control module controls the liquid inlet to add water with the quantity of mc 4;

the first viscosity difference Δ η a is calculated as follows,

△ηa＝(η-ηmax)×δa；

wherein δ a represents a first viscosity difference coefficient, and δ a ═ η/η max.

Further, the central control module is further provided with a preset second viscosity difference matrix Δ η b0(Δ η b1, Δ η b2, Δ η b3, Δ η b4), wherein Δ η b1 represents a preset second viscosity first difference, Δ η b2 represents a preset second viscosity second difference, Δ η b3 represents a preset second viscosity third difference, and Δ η b4 represents a preset second viscosity fourth difference;

when the central control module judges that the comparison result does not accord with a second preset condition and controls the temperature regulating valve to regulate the temperature, the central control module calculates a second viscosity difference value delta eta b, and when the calculation is completed, the central control module compares the second viscosity difference value delta eta b with parameters in a preset second viscosity difference matrix delta eta b 0:

if delta eta b is equal to delta eta bi, the central control module controls the temperature regulating valve to increase the temperature of Qi quantity to regulate the temperature of the traditional Chinese medicine preparation mixture, wherein Qi represents parameters in a preset temperature regulating quantity matrix Q0, and i is equal to 1,2,3 and 4;

the second viscosity difference Δ η b is calculated as follows,

△ηb＝(ηmin-η)×δb；

wherein δ b represents a second viscosity difference coefficient, and δ b ═ η min/η.

Further, the central control module is also provided with a preset maximum temperature Hmax of the mixture for preparing the traditional Chinese medicine;

when the central control module controls the temperature regulating valve to raise the temperature so as to regulate the temperature of the traditional Chinese medicine preparation mixture, the central control module controls the temperature measuring instrument to measure the temperature of the traditional Chinese medicine preparation mixture again, and compares the measured temperature Hs with a preset traditional Chinese medicine preparation mixture highest temperature Hmax:

if Hs is less than or equal to Hmax, the central control module judges that the traditional Chinese medicine preparation mixture can be used for preparing traditional Chinese medicine liquid or traditional Chinese medicine ointment or traditional Chinese medicine particles;

and if Hs is larger than Hmax, the central control module controls a refrigerating device to cool the traditional Chinese medicine preparation mixture.

Compared with the prior art, the method has the advantages that the real-time temperature of the traditional Chinese medicine preparation mixture is compared with the preset temperature of the traditional Chinese medicine preparation mixture to determine whether the temperature of the traditional Chinese medicine preparation mixture needs to be adjusted or not, the temperature difference value is compared with the parameter in the preset temperature difference value matrix delta H0 to determine the temperature adjusting amount of the temperature adjusting valve for adjusting the temperature in the pharmaceutical tank, the real-time concentration of the traditional Chinese medicine preparation mixture is compared with the preset concentration of the traditional Chinese medicine preparation mixture to determine whether the concentration of the traditional Chinese medicine preparation mixture needs to be further measured or whether the traditional Chinese medicine raw materials need to be added or whether the traditional Chinese medicine auxiliary materials need to be added or not, the concentration difference value is matched with the parameter in the preset concentration difference value interval matrix delta Sa0 to determine the amount of the traditional Chinese medicine raw materials to be added, the measured pressure in the pharmaceutical tank is compared with the parameter in the preset pressure matrix N0 of the pharmaceutical tank to determine the, the real-time viscosity of the traditional Chinese medicine preparation mixture is compared with the parameters in the preset traditional Chinese medicine preparation mixture viscosity matrix eta 0 to determine whether the traditional Chinese medicine preparation mixture can be used for preparing traditional Chinese medicine liquid or traditional Chinese medicine ointment or traditional Chinese medicine particles, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration and viscosity of raw materials in the preparation process, the preparation efficiency is improved, and the traditional Chinese medicine particles, the traditional Chinese medicine ointment and the traditional Chinese medicine liquid can be prepared by the same equipment.

Furthermore, the embodiment of the invention compares the real-time concentration S of the traditional Chinese medicine preparation mixture with the preset concentration S0 of the traditional Chinese medicine preparation mixture to determine whether the concentration of the traditional Chinese medicine preparation mixture needs to be further measured or whether traditional Chinese medicine raw materials need to be added or traditional Chinese medicine auxiliary materials need to be added, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration of the raw materials in the preparation process, and the preparation efficiency is improved.

Furthermore, according to the embodiment of the invention, the amount of the added traditional Chinese medicine raw materials is determined by matching the concentration difference value delta Sa with the parameters in the preset concentration difference value interval matrix delta Sa0, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration of the raw materials in the preparation process, and the preparation efficiency is improved.

Furthermore, the embodiment of the invention compares the pressure N of the pharmaceutical tank with the parameters in the preset pharmaceutical tank pressure matrix N0 to determine the amount of the added traditional Chinese medicine auxiliary materials, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration of the raw materials in the preparation process, and the preparation efficiency is improved.

Furthermore, the embodiment of the invention compares the real-time viscosity eta of the traditional Chinese medicine preparation mixture with the parameters in the preset viscosity matrix eta 0 of the traditional Chinese medicine preparation mixture to determine whether the traditional Chinese medicine preparation mixture can be used for preparing traditional Chinese medicine liquid or traditional Chinese medicine ointment or traditional Chinese medicine particles, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration and viscosity of the raw materials in the preparation process, and the preparation efficiency is improved.

According to the embodiment of the invention, the density rho of the mixture prepared from the traditional Chinese medicines in real time is compared with the parameters in the density matrix rho 0 of the mixture prepared from the traditional Chinese medicines in a preset mode to determine the traditional Chinese medicine state of the mixture prepared from the traditional Chinese medicines for preparation, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration and viscosity of raw materials in the preparation process, the preparation efficiency is improved, and the traditional Chinese medicine particles, the traditional Chinese medicine ointment and the traditional Chinese medicine liquid can be prepared by the same equipment.

Furthermore, the addition amount of water when the viscosity of the traditional Chinese medicine preparation mixture is adjusted by adding water into the liquid inlet is determined by comparing the first viscosity difference value delta eta a with the parameters in the preset first viscosity difference value matrix delta eta a0, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the viscosity of raw materials in the preparation process, and the preparation efficiency is improved.

Furthermore, the embodiment of the invention compares the second viscosity difference value delta eta b with the parameters in the preset second viscosity difference value matrix delta eta b0 to determine the adjustment amount of the temperature when the temperature is adjusted by the temperature adjusting valve to adjust the viscosity of the traditional Chinese medicine preparation mixture, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the viscosity of the raw materials in the preparation process, and the preparation efficiency is improved.

Furthermore, the embodiment of the invention compares the re-measured temperature Hs of the mixture of the traditional Chinese medicine preparation with the preset highest temperature Hmax of the mixture of the traditional Chinese medicine preparation to determine whether the mixture of the traditional Chinese medicine preparation needs to be cooled down by the refrigerating device, so that the temperature in the preparation process can be accurately controlled, and the preparation efficiency is effectively improved.

Drawings

FIG. 1 is a schematic structural diagram of a device for preparing a Chinese herbal compound for reducing the vaccine reaction of livestock and poultry according to the present invention;

FIG. 2 is a schematic flow chart of a preparation process of the traditional Chinese medicine compound for reducing livestock and poultry vaccine reaction according to the invention;

the notation in the figure is: 1. a medicine preparation tank; 11. a first feed port; 12. a second feed port; 13. a liquid inlet; 14. a stirrer; 15. a first control valve; 16. a second control valve; 17. a third control valve; 18. a temperature regulating valve; 2. a first storage tank; 3. a second storage tank; 4. a third storage tank; 5. a refrigeration device.

Detailed Description

In order that the objects and advantages of the invention will be more clearly understood, the invention is further described below with reference to examples; it should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

Preferred embodiments of the present invention are described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are only for explaining the technical principle of the present invention, and do not limit the scope of the present invention.

It should be noted that in the description of the present invention, the terms of direction or positional relationship indicated by the terms "upper", "lower", "left", "right", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, which are only for convenience of description, and do not indicate or imply that the device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention.

Furthermore, it should be noted that, in the description of the present invention, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

Referring to fig. 1 and 2, fig. 1 is a schematic structural diagram of a device for preparing a traditional Chinese medicine compound for reducing livestock and poultry vaccine reaction according to the present invention, fig. 2 is a schematic flow diagram of a process for preparing a traditional Chinese medicine compound for reducing livestock and poultry vaccine reaction according to the present invention, and the device for preparing a traditional Chinese medicine compound for reducing livestock and poultry vaccine reaction according to the present embodiment includes:

the system comprises a medicine preparation tank 1, a first storage tank 2, a second storage tank 3, a third storage tank 4 and a refrigerating device 5, wherein the medicine preparation tank 1 is respectively connected with the first storage tank 2, the second storage tank 3, the third storage tank 4 and the refrigerating device 5, the medicine preparation tank 1 is used for preparing a mixture according to a traditional Chinese medicine compound, the first storage tank 2 is used for preparing a traditional Chinese medicine liquid, the second storage tank 3 is used for preparing a traditional Chinese medicine ointment, and the third storage tank 4 is used for preparing traditional Chinese medicine particles;

the medicine preparation tank 1 comprises a first feed port 11, a second feed port 12, a liquid inlet 13, a stirrer 14, a first control valve 15, a second control valve 16, a third control valve 17 and a temperature regulating valve 18, wherein the first feed port 11, the second feed port 12 and the liquid inlet 13 are all arranged on the medicine preparation tank 1, the first feed port 11 is used for adding traditional Chinese medicine raw materials into the medicine preparation tank 1, the second feed port 12 is used for adding traditional Chinese medicine auxiliary materials into the medicine preparation tank 1, and the liquid inlet 13 is used for adding water into the medicine preparation tank 1; the stirrer 14 is arranged in the medicine preparation tank 1 and extends to two ends to mix the traditional Chinese medicine raw materials, the traditional Chinese medicine auxiliary materials and water; the first control valve 15, the second control valve 16 and the third control valve 17 are all arranged at the bottom of the medicine preparation tank 1, and the first control valve 15 is connected with the first storage tank 2 and used for introducing a traditional Chinese medicine preparation mixture capable of being used for preparing traditional Chinese medicine liquid into the first storage tank 2; the second control valve 16 is connected to the second storage tank 3, and is used for introducing a traditional Chinese medicine preparation mixture capable of being used for preparing traditional Chinese medicine ointment into the second storage tank 3; the third control valve 17 is connected to the third storage tank 4 to introduce a herbal preparation mixture capable of being used to prepare herbal granules into the third storage tank 4.

With reference to fig. 1, based on the above apparatus for preparing a Chinese herbal compound for reducing livestock and poultry vaccine reaction, the process for preparing a Chinese herbal compound for reducing livestock and poultry vaccine reaction of the embodiment includes:

step one, adding traditional Chinese medicine raw materials into a pharmaceutical tank 1 through a first feeding hole 11, adding traditional Chinese medicine auxiliary materials into the pharmaceutical tank 1 through a second feeding hole 12, adding water into the pharmaceutical tank 1 through a liquid inlet 13, and mixing the traditional Chinese medicine raw materials, the traditional Chinese medicine auxiliary materials and the water by using a stirrer 14 to form a traditional Chinese medicine preparation mixture; in the stirring process, the central control module controls the temperature measuring instrument to measure the temperature of the traditional Chinese medicine preparation mixture and compare the measured real-time temperature with the preset traditional Chinese medicine preparation mixture temperature, when the central control module judges that the comparison result does not meet a first preset condition, the central control module calculates a temperature difference adjusting coefficient, when the calculation is finished, the central control module calculates a temperature difference value by combining the temperature adjusting coefficient and compares the temperature difference value with the parameters in a preset temperature difference value matrix delta H0, and the central control module controls the temperature adjusting valve 18 to adjust the temperature in the medicine preparation tank 1 according to the comparison result;

when the central control module judges that the comparison result meets a first preset condition, the central control module controls a concentration measuring instrument to measure the concentration of the traditional Chinese medicine preparation mixture and compares the measured real-time concentration with the preset concentration of the traditional Chinese medicine preparation mixture, and the central control module judges according to the comparison result that a viscosity measuring instrument is controlled to measure the viscosity of the traditional Chinese medicine preparation mixture or controls a first feed port 11 to add traditional Chinese medicine raw materials or controls a second feed port 12 to add traditional Chinese medicine auxiliary materials;

when the central control module controls the first feed port 11 to add the traditional Chinese medicine raw materials, the central control module calculates a concentration difference value and matches the concentration difference value with the parameter in a preset concentration difference value interval matrix delta Sa0 to determine the amount of the traditional Chinese medicine raw materials to be added, and when the determination is finished, the central control module controls the first feed port 11 to add the traditional Chinese medicine raw materials;

when the central control module controls the second feed port 12 to add the traditional Chinese medicine auxiliary materials, the central control module controls the pressure measuring instrument to measure the pressure in the medicine preparation tank 1 and compares the measured pressure with the parameters in the preset pressure matrix N0 of the medicine preparation tank 1 to determine the amount of the traditional Chinese medicine auxiliary materials to be added, and when the determination is finished, the central control module controls the second feed port 12 to add the traditional Chinese medicine auxiliary materials;

when the central control module judges that the comparison result meets a second preset condition, the central control module controls the liquid inlet 13 to add water or controls the temperature regulating valve 18 to regulate the temperature;

step two, when the central control module judges that the traditional Chinese medicine preparation mixture is used for preparing traditional Chinese medicine liquid, opening a first control valve 15 to enable the traditional Chinese medicine preparation mixture to flow into a first storage tank 2;

step three, when the central control module judges that the traditional Chinese medicine preparation mixture is used for preparing traditional Chinese medicine ointment, opening a second control valve 16 to enable the traditional Chinese medicine preparation mixture to flow into a second storage tank 3;

step four, when the central control module judges that the traditional Chinese medicine preparation mixture is used for preparing traditional Chinese medicine particles, a third control valve 17 is opened to enable the traditional Chinese medicine preparation mixture to flow into a third storage tank 4;

the medicine preparation tank 1, the temperature measuring instrument, the concentration measuring instrument and the viscosity measuring instrument are wirelessly connected with the central control module, the central control module is used for controlling the preparation process, and a matrix is arranged in the central control module;

if the delta H is less than the delta H1, the central control module controls the temperature adjusting valve 18 to increase the temperature of Q1 quantity;

if the delta H is not more than delta H1 and less than delta H2, the central control module controls the temperature of the temperature adjusting valve 18 to increase the temperature by the amount of Q2;

if the delta H is not more than delta H2 and less than delta H3, the central control module controls the temperature of the temperature adjusting valve 18 to increase the temperature by the amount of Q3;

if the delta H is not less than or equal to the delta H3, the central control module controls the temperature regulating valve 18 to raise the temperature of the Q4 amount;

σ＝(H/H0)×((H0+H)/(H0+H))；

the calculation formula of the temperature difference Δ H is as follows,

△H＝(H0-H)×σ；

The embodiment of the invention compares the real-time temperature of the traditional Chinese medicine preparation mixture with the preset temperature of the traditional Chinese medicine preparation mixture to determine whether the temperature of the traditional Chinese medicine preparation mixture needs to be adjusted or not, compares the temperature difference with the parameter in a preset temperature difference matrix delta H0 to determine the temperature adjustment amount of the temperature adjustment valve 18 for adjusting the temperature in the pharmaceutical tank 1, compares the real-time concentration of the traditional Chinese medicine preparation mixture with the preset concentration of the traditional Chinese medicine preparation mixture to determine whether the concentration of the traditional Chinese medicine preparation mixture needs to be further measured or whether the traditional Chinese medicine raw materials need to be added or whether the traditional Chinese medicine auxiliary materials need to be added or not, matches the concentration difference with the parameter in a preset concentration difference interval matrix delta Sa0 to determine the amount of the traditional Chinese medicine raw materials to be added, and compares the measured pressure in the pharmaceutical tank 1 with the parameter in a pressure matrix N0 of the pharmaceutical tank 1 to determine the amount of the traditional Chinese medicine auxiliary materials, the real-time viscosity of the traditional Chinese medicine preparation mixture is compared with the parameters in the preset traditional Chinese medicine preparation mixture viscosity matrix eta 0 to determine whether the traditional Chinese medicine preparation mixture can be used for preparing traditional Chinese medicine liquid or traditional Chinese medicine ointment or traditional Chinese medicine particles, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration and viscosity of raw materials in the preparation process, the preparation efficiency is improved, and the traditional Chinese medicine particles, the traditional Chinese medicine ointment and the traditional Chinese medicine liquid can be prepared by the same equipment.

Specifically, in the stirring process, the real-time temperature of the traditional Chinese medicine preparation mixture measured by the temperature measuring instrument is H, meanwhile, the central control module is further provided with a preset traditional Chinese medicine preparation mixture temperature H0, and in the stirring process, the central control module compares H with H0:

The embodiment of the invention compares the real-time temperature H of the traditional Chinese medicine preparation mixture with the preset temperature H0 of the traditional Chinese medicine preparation mixture to determine whether the temperature of the traditional Chinese medicine preparation mixture needs to be adjusted.

Specifically, the central control module is also provided with a preset concentration S0 of the traditional Chinese medicine preparation mixture;

if S is less than S0, the central control module controls the first feed inlet 11 to add the traditional Chinese medicine raw materials;

if S is more than S0, the central control module controls the first feed inlet 11 to add the traditional Chinese medicine raw materials.

According to the embodiment of the invention, the real-time concentration S of the traditional Chinese medicine preparation mixture is compared with the preset concentration S0 of the traditional Chinese medicine preparation mixture to determine whether the concentration of the traditional Chinese medicine preparation mixture needs to be further measured or whether traditional Chinese medicine raw materials need to be added or whether traditional Chinese medicine auxiliary materials need to be added, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration of the raw materials in the preparation process, and the preparation efficiency is improved.

Specifically, the central control module is further provided with a preset concentration difference interval matrix Δ Sa0(Δ Sa1, Δ Sa2, Δ Sa3, Δ Sa4), wherein Δ Sa1 represents a first difference interval of preset concentration, Δ Sa2 represents a second difference interval of preset concentration, Δ Sa3 represents a third difference interval of preset concentration, Δ Sa4 represents a fourth difference interval of preset concentration, and numerical ranges of the intervals are not overlapped;

when the central control module controls the first feed inlet 11 to add the traditional Chinese medicine raw materials, the central control module calculates a concentration difference value delta Sa and matches the concentration difference value delta Sa with parameters in a preset concentration difference value interval matrix delta Sa 0:

if the delta Sa is within the range of delta Sai, the central control module controls the first feed inlet 11 to add mai amounts of traditional Chinese medicine raw materials, i is 1,2,3 and 4;

the concentration difference Δ Sa is calculated as follows:

△Sa＝(S0-S)×β；

wherein β represents a concentration adjustment coefficient, and β is S0/S.

According to the embodiment of the invention, the concentration difference value delta Sa is matched with the parameters in the preset concentration difference value interval matrix delta Sa0 to determine the amount of the added traditional Chinese medicine raw materials, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration of the raw materials in the preparation process, and the preparation efficiency is improved.

Specifically, the central control module is further provided with a preset medicine tank 1 pressure matrix N0(N1, N2 and N3), wherein N1 represents a preset medicine tank 1 first pressure, N2 represents a preset medicine tank 1 second pressure, N3 represents a preset medicine tank 1 third pressure, and N1 < N2 < N3;

when the central control module controls the second feeding hole 12 to add the traditional Chinese medicine auxiliary materials, the central control module controls the pressure measuring instrument to measure the pressure in the medicine preparation tank 1 and compares the measured pressure N with the parameters in a preset pressure matrix N0 of the medicine preparation tank 1:

if N is less than N1, the central control module controls the second feed inlet 12 to add the traditional Chinese medicine auxiliary materials with the amount of mb 1;

if N is more than or equal to N1 and less than N2, the central control module controls the second feed inlet 12 to add the traditional Chinese medicine auxiliary materials with the amount of mb 2;

if N is more than or equal to N2 and less than N3, the central control module controls the second feed inlet 12 to add the traditional Chinese medicine auxiliary materials with the amount of mb 3;

if N is more than or equal to N3, the central control module controls the second feeding hole 12 to add the traditional Chinese medicine auxiliary materials with the amount of mb 4.

According to the embodiment of the invention, the amount of the added traditional Chinese medicine auxiliary materials is determined by comparing the pressure N of the medicine preparation tank 1 with the parameters in the preset pressure matrix N0 of the medicine preparation tank 1, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration of the raw materials in the preparation process, and the preparation efficiency is improved.

Specifically, the central control module is further provided with a preset traditional Chinese medicine preparation mixture viscosity matrix eta 0 (eta min, eta max), wherein eta min represents the lowest viscosity of the preset traditional Chinese medicine preparation mixture, eta max represents the highest viscosity of the preset traditional Chinese medicine preparation mixture, and eta min is less than eta max;

if eta is less than eta min, the central control module judges that the comparison result does not accord with a second preset condition and controls the temperature regulating valve 18 to regulate the temperature;

if eta is larger than eta max, the central control module judges that the comparison result does not accord with the second preset condition and controls the liquid inlet 13 to add water.

According to the embodiment of the invention, the real-time viscosity eta of the traditional Chinese medicine preparation mixture is compared with the parameters in the preset viscosity matrix eta 0 of the traditional Chinese medicine preparation mixture to determine whether the traditional Chinese medicine preparation mixture can be used for preparing traditional Chinese medicine liquid or traditional Chinese medicine ointment or traditional Chinese medicine particles, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the concentration and viscosity of raw materials in the preparation process, and the preparation efficiency is improved.

Specifically, the central control module is further provided with a density matrix rho 0 (rho 1, rho 2, rho 3) of the preset traditional Chinese medicine preparation mixture, wherein rho 1 represents a first density of the preset traditional Chinese medicine preparation mixture, rho 2 represents a second density of the preset traditional Chinese medicine preparation mixture, rho 3 represents a third density of the preset traditional Chinese medicine preparation mixture, and rho 1 is greater than rho 2 and is greater than rho 3;

Specifically, the central control module is further provided with a preset first viscosity difference matrix Δ η a0 ([ delta ] η a1, [ delta ] η a2, [ delta ] η a3), wherein Δ η a1 represents a preset first viscosity first difference value, [ delta ] a2 represents a preset first viscosity second difference value, [ delta ] a3 represents a preset first viscosity third difference value, [ delta ] a1 < [ delta ] η a2 < [ delta ] η a 3;

when the central control module judges that the comparison result does not accord with a second preset condition and controls the liquid inlet 13 to add water, the central control module calculates a first viscosity difference value delta eta a, and when the calculation is completed, the central control module compares the first viscosity difference value delta eta a with parameters in a preset first viscosity difference matrix delta eta a 0:

if the delta eta a is less than the delta eta a1, the central control module controls the liquid inlet 13 to add water with the amount of mc 1;

if the delta eta a is not more than delta eta a1 and is less than delta eta a2, the central control module controls the liquid inlet 13 to add water with the amount of mc 2;

if the delta eta a is not more than delta eta a2 and is less than delta eta a3, the central control module controls the liquid inlet 13 to add water with the amount of mc 3;

if the delta eta a is more than or equal to the delta eta a3, the central control module controls the liquid inlet 13 to add water with the quantity of mc 4;

the first viscosity difference Δ η a is calculated as follows,

△ηa＝(η-ηmax)×δa；

According to the embodiment of the invention, the addition amount of water when the viscosity of the traditional Chinese medicine preparation mixture is adjusted by adding water into the liquid inlet 13 is determined by comparing the first viscosity difference value delta eta a with the parameters in the preset first viscosity difference value matrix delta eta a0, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the viscosity of raw materials in the preparation process, and the preparation efficiency is improved.

Specifically, the central control module is further provided with a preset second viscosity difference matrix Δ η b0(Δ η b1, Δ η b2, Δ η b3, Δ η b4), wherein Δ η b1 represents a preset second viscosity first difference, Δ η b2 represents a preset second viscosity second difference, Δ η b3 represents a preset second viscosity third difference, and Δ η b4 represents a preset second viscosity fourth difference;

when the central control module judges that the comparison result does not accord with a second preset condition and controls the temperature regulating valve 18 to regulate the temperature, the central control module calculates a second viscosity difference value delta eta b, and when the calculation is completed, the central control module compares the second viscosity difference value delta eta b with parameters in a preset second viscosity difference matrix delta eta b 0:

if Δ η b is equal to Δ η bi, the central control module controls the temperature regulating valve 18 to increase the temperature by Qi quantity to regulate the temperature of the traditional Chinese medicine preparation mixture, Qi represents a parameter in a preset temperature regulating quantity matrix Q0, and i is equal to 1,2,3, 4;

the second viscosity difference Δ η b is calculated as follows,

△ηb＝(ηmin-η)×δb；

According to the embodiment of the invention, the second viscosity difference value delta eta b is compared with the parameters in the preset second viscosity difference value matrix delta eta b0 to determine the temperature regulating quantity when the temperature regulating valve 18 regulates the temperature to regulate the viscosity of the traditional Chinese medicine preparation mixture, so that the preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction can accurately control the viscosity of the raw materials in the preparation process, and the preparation efficiency is improved.

Specifically, the central control module is also provided with a preset maximum temperature Hmax of the traditional Chinese medicine preparation mixture;

when the central control module controls the temperature regulating valve 18 to raise the temperature so as to regulate the temperature of the Chinese medicine preparation mixture, the central control module controls the temperature measuring instrument to measure the temperature of the Chinese medicine preparation mixture again, and compares the measured temperature Hs with a preset maximum temperature Hmax of the Chinese medicine preparation mixture:

and if Hs is larger than Hmax, the central control module controls a refrigerating device 5 to cool the traditional Chinese medicine preparation mixture.

According to the embodiment of the invention, the re-measured temperature Hs of the traditional Chinese medicine preparation mixture is compared with the preset highest temperature Hmax of the traditional Chinese medicine preparation mixture to determine whether the traditional Chinese medicine preparation mixture needs to be cooled by the refrigerating device 5, so that the temperature in the preparation process can be accurately controlled, and the preparation efficiency is effectively improved.

So far, the technical solutions of the present invention have been described in connection with the preferred embodiments shown in the drawings, but it is easily understood by those skilled in the art that the scope of the present invention is obviously not limited to these specific embodiments. Equivalent changes or substitutions of related technical features can be made by those skilled in the art without departing from the principle of the invention, and the technical scheme after the changes or substitutions can fall into the protection scope of the invention.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention; various modifications and alterations to this invention will become apparent to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A preparation process of a traditional Chinese medicine compound for reducing livestock and poultry vaccine reaction is characterized by comprising the following steps of:

σ＝(H/H0)×((H0+H)/(H0+H))；

the calculation formula of the temperature difference Δ H is as follows,

△H＝(H0-H)×σ；

2. The preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction according to claim 1, wherein the real-time temperature of the traditional Chinese medicine preparation mixture measured by the temperature measuring instrument is H during stirring, and meanwhile, the central control module is further provided with a preset traditional Chinese medicine preparation mixture temperature H0, and the central control module compares H with H0 during stirring:

3. The preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction according to claim 2, wherein the central control module is further provided with a preset concentration S0 of a traditional Chinese medicine preparation mixture;

4. The preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction according to claim 3, wherein the central control module is further provided with a preset concentration difference interval matrix delta Sa0 (delta Sa1, delta Sa2, delta Sa3 and delta Sa4), wherein delta Sa1 represents a first difference interval of the preset concentration, delta Sa2 represents a second difference interval of the preset concentration, delta Sa3 represents a third difference interval of the preset concentration, delta Sa4 represents a fourth difference interval of the preset concentration, and the numerical ranges of the intervals are not overlapped;

the concentration difference Δ Sa is calculated as follows:

△Sa＝(S0-S)×β；

wherein β represents a concentration adjustment coefficient, and β is S0/S.

5. The process for preparing a Chinese herbal compound for reducing livestock and poultry vaccine reaction according to claim 3, wherein the central control module is further provided with a preset pharmaceutical tank pressure matrix N0(N1, N2, N3), wherein N1 represents a preset pharmaceutical tank first pressure, N2 represents a preset pharmaceutical tank second pressure, N3 represents a preset pharmaceutical tank third pressure, and N1 < N2 < N3;

6. The process for preparing a Chinese herbal compound for reducing livestock and poultry vaccine reaction according to claim 3, wherein the central control module is further provided with a preset Chinese herbal medicine preparation mixture viscosity matrix η 0(η min, η max), wherein η min represents the preset Chinese herbal medicine preparation mixture minimum viscosity, η max represents the preset Chinese herbal medicine preparation mixture maximum viscosity, and η min < η max;

7. The preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction according to claim 6, wherein the central control module is further provided with a density matrix ρ 0(ρ 1, ρ 2, ρ 3) of the preset traditional Chinese medicine preparation mixture, wherein ρ 1 represents a first density of the preset traditional Chinese medicine preparation mixture, ρ 2 represents a second density of the preset traditional Chinese medicine preparation mixture, ρ 3 represents a third density of the preset traditional Chinese medicine preparation mixture, and ρ 1 < ρ 2 < ρ 3;

8. The process for preparing a herbal compound for reducing a vaccine response in livestock and poultry according to claim 6, wherein the central control module is further provided with a preset first viscosity difference matrix Δ η a0(Δ η a1, Δ η a2, Δ η a3), wherein Δ η a1 represents a preset first viscosity first difference, Δ η a2 represents a preset first viscosity second difference, Δ η a3 represents a preset first viscosity third difference, and Δ η a1 < Δη a2 < Δη a 3;

the first viscosity difference Δ η a is calculated as follows,

△ηa＝(η-ηmax)×δa；

9. The process for preparing a herbal compound for reducing livestock and poultry vaccine reaction according to claim 6, wherein the central control module is further provided with a preset second viscosity difference matrix Δ η b0(Δ η b1, Δ η b2, Δ η b3, Δ η b4), wherein Δ η b1 represents a preset second viscosity first difference, Δ η b2 represents a preset second viscosity second difference, Δ η b3 represents a preset second viscosity third difference, and Δ η b4 represents a preset second viscosity fourth difference;

the second viscosity difference Δ η b is calculated as follows,

△ηb＝(ηmin-η)×δb；

10. The preparation process of the traditional Chinese medicine compound for reducing the livestock and poultry vaccine reaction according to claim 9, wherein the central control module is further provided with a preset maximum temperature Hmax of the traditional Chinese medicine preparation mixture;