CN112971699B - Two-stage image stabilizing device applied to eye movement compensation of eye fundus imaging instrument - Google Patents
Two-stage image stabilizing device applied to eye movement compensation of eye fundus imaging instrument Download PDFInfo
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- CN112971699B CN112971699B CN202110294060.9A CN202110294060A CN112971699B CN 112971699 B CN112971699 B CN 112971699B CN 202110294060 A CN202110294060 A CN 202110294060A CN 112971699 B CN112971699 B CN 112971699B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0008—Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/14—Arrangements specially adapted for eye photography
Abstract
The invention discloses a two-stage image stabilizing device applied to eye movement compensation of an eye fundus imaging instrument, which comprises a coarse image stabilizing beacon light source, a coarse image stabilizing detector, a fine image stabilizing illumination light source, a scanning image stabilizing mirror and an image stabilizing mirror deflection control module; the coarse image stabilization detector is used for measuring the displacement of a light spot image formed on the fundus after the beacon light emitted by the coarse image stabilization beacon light source passes through the fundus imaging light path, so as to obtain the coarse movement amount of the eye movement; the fine image stabilization detector is used for acquiring an eyeground area image which is provided with illumination by eyeground illumination light emitted by the fine image stabilization illumination light source and calculating to obtain fine movement amount of eye movement of a human eye; and the image stabilizing mirror deflection control module calculates a deflection compensation instruction according to the coarse motion amount and the fine motion amount and controls the scanning image stabilizing mirror to deflect according to the deflection compensation instruction. The invention can realize rapid and high-precision eye movement compensation image stabilization of the fundus imaging instrument, and obtain more stable images, thereby improving the fundus imaging quality.
Description
Technical Field
The invention relates to the technical field of fundus imaging, in particular to a two-stage image stabilizing device applied to eye movement compensation of a fundus imaging instrument.
Background
The human eye is an important visual organ and fundus imaging is often used to provide a diagnosis of fundus disease or certain systemic diseases. The human eye has eye movement, namely physiological fundus vibration, and the vibration can cause fundus imaging image blurring, reduce imaging quality and influence the diagnosis capability of diseases.
Most of eye movement compensation image stabilization technologies used by the existing eye fundus imaging equipment irradiate the eye fundus by using a beacon light source, focus the beacon light source on the eye fundus to form a light spot, monitor the movement of the light spot, calculate the eye movement amplitude and direction in real time according to the light spot displacement, and accordingly adjust the light path direction to perform eye movement compensation. Because the human eyes have aberration, the facula has a certain diffusion range on the eyeground, and the calculation precision of the facula displacement is reduced, so that the eye movement compensation precision is reduced, and the imaging quality is limited finally.
Disclosure of Invention
The invention aims to overcome the defects of an eye movement compensation image stabilization technology in the existing eye fundus imaging instrument, and provides a two-stage image stabilization device applied to eye movement compensation of the eye fundus imaging instrument.
In order to solve the problems, the invention adopts the following technical scheme:
a double-stage image stabilization device applied to eye movement compensation of an eye fundus imaging instrument comprises a coarse image stabilization beacon light source, a coarse image stabilization detector, a fine image stabilization illumination light source, a scanning image stabilization mirror and an image stabilization mirror deflection control module;
the double-stage image stabilizing device is arranged in an eye fundus imaging optical path and is used for performing eye movement compensation on the eye fundus imaging optical path, and the eye fundus imaging optical path comprises a human eye to be detected, a scanning image stabilizing module front optical path, a scanning image stabilizing module rear optical path and an eye fundus imaging unit;
beacon light emitted by the coarse-level image stabilization beacon light source enters the fundus of the eye of the detected person after passing through the scanning image stabilization module rear light path, the scanning image stabilization mirror and the scanning image stabilization module front light path, is focused into a light spot on the fundus, and returns to the coarse-level image stabilization detector along the original path after passing through beacon light reflected by the fundus, so that a light spot image is formed on the coarse-level image stabilization detector, and the coarse-level image stabilization detector measures the displacement of the light spot image to obtain the coarse-level movement amount of the eye movement of the human eye;
the fundus illumination light emitted by the precise image stabilization illumination light source enters the fundus of the eye to be detected, the fundus illumination light reflected by a fundus region enters the precise image stabilization detector after passing through the scanning image stabilization module front light path, the scanning image stabilization mirror and the scanning image stabilization module rear light path, the precise image stabilization detector images the fundus region, collects a plurality of frames of fundus region images, processes a plurality of frames of fundus region images by using an image digital processing method, and calculates to obtain the precise movement amount of the eye movement, wherein the image digital processing method is any one of an image matching processing method, a frequency spectrum analysis processing method and a deep learning processing method;
and the image stabilizing mirror deflection control module calculates a deflection compensation instruction according to the coarse motion amount and the fine motion amount, controls the scanning image stabilizing mirror to deflect according to the deflection compensation instruction, and adjusts the direction of fundus illumination light to enable the fundus imaging unit to acquire a stable fundus image after eye movement compensation.
Compared with the prior art, the invention has the following beneficial effects:
the invention provides a two-stage image stabilizing device applied to eye movement compensation of an eye fundus imaging instrument, which adopts a coarse and fine two-stage image stabilizing mode to carry out eye movement compensation image stabilization, namely, the coarse movement amount of the eye movement of a human eye is calculated by using a light spot image of beacon light, and the fine movement amount of the eye movement of the human eye is calculated by using a multi-frame eye fundus region image through an image digital processing method. The beacon light spot method is high in measurement speed, accuracy superior to that of a pixel level can be achieved through image motion amount calculation, and compared with the beacon light spot method that the motion amount measurement accuracy is inferior to that of the pixel level, the accuracy is higher, so that two-stage image stabilization is performed by combining the two methods, rapid and high-accuracy eye movement compensation image stabilization of an eye fundus imaging instrument can be achieved, a more stable image is obtained, and therefore the eye fundus imaging quality is improved.
Drawings
Fig. 1 is a schematic structural diagram of a two-stage image stabilizing device applied to eye movement compensation of a fundus imaging instrument according to an embodiment of the present invention.
Detailed Description
The technical solution of the present invention will be described in detail with reference to the accompanying drawings and preferred embodiments.
As shown in fig. 1, in one embodiment of the present invention, the present invention provides a two-stage image stabilization device applied to eye movement compensation of a fundus imaging instrument, the device includes a coarse-stage image stabilization beacon light source 1, a coarse-stage image stabilization detector 2, a fine-stage image stabilization detector 3, a fine-stage image stabilization illumination light source 4, a scanning image stabilization mirror 5, and an image stabilization mirror deflection control module. Beacon light emitted by a coarse image stabilization beacon light source 1 is reflected by the eye ground and finally enters a coarse image stabilization detector 2, eye ground illumination light emitted by a fine image stabilization illumination light source 4 is reflected by the eye ground and finally enters a fine image stabilization detector 3, beacon displacement under the dynamic environment of the human eye is measured by the coarse image stabilization detector 2, local image displacement of the eye ground under the dynamic environment of the human eye is measured by the fine image stabilization detector 3, coarse movement amount and fine movement amount of the human eye movement are converted from the measurement result and are respectively sent to an image stabilization mirror deflection control module, the image stabilization mirror deflection control module controls the deflection angle of a scanning image stabilization mirror 5, the light beam direction irradiated by the eye ground is adjusted, and eye movement compensation image stabilization is realized.
The double-stage image stabilizing device is arranged in an eye fundus imaging optical path and is used for carrying out eye movement compensation on the eye fundus imaging optical path, wherein the eye fundus imaging optical path comprises a human eye to be detected 6, a scanning image stabilizing module front optical path 7, a scanning image stabilizing module rear optical path 8 and an eye fundus imaging unit 9.
Specifically, in this embodiment, the beacon light emitted by the coarse-scale image stabilization beacon light source 1 enters the fundus of the eye 6 of the human being to be examined after passing through the scanning image stabilization module rear light path 8, the scanning image stabilization mirror 5 and the scanning image stabilization module front light path 7, and is focused on the fundus to form a light spot, the light spot is used as a coarse-scale measurement beacon for eye movement, the beacon light reflected by the fundus returns to the coarse-scale image stabilization detector 2 along the original path, a light spot image is formed on the coarse-scale image stabilization detector 2, the light spot image moves on the coarse-scale image stabilization detector 2 under the influence of eye movement of the human eye 6, the coarse-scale image stabilization detector 2 can measure the displacement of the light spot image, and the coarse-scale movement amount of the eye movement is calculated according to the amplitude and direction of the light spot movement, the physiological structure of the human eye and the optical path structure of the eye fundus imaging instrument.
Fundus illumination light emitted by the fine image stabilization illumination light source 4 enters the fundus of a human eye 6 to be detected to illuminate a part of the region of the fundus, the fundus illumination light reflected by the fundus region enters the fine image stabilization detector 3 after passing through the scanning image stabilization module front light path 7, the scanning image stabilization mirror 5 and the scanning image stabilization module rear light path 8 to serve as a fine measurement beacon of the human eye movement, the fine image stabilization detector 3 images the fundus region, a plurality of frames of fundus region images are collected, a plurality of frames of fundus region images are processed by using an image digital processing method, and the fine movement amount of the human eye movement is calculated through the movement amount of the images. The image digital processing method for processing the fundus region images in the present embodiment includes, but is not limited to, an image matching processing method, a spectral analysis processing method, a deep learning processing method, and the like, as long as a method of acquiring the amount of eye movement of the human eye from the plurality of frames of fundus region images is within the scope of the present patent. Optionally, the fundus region image acquired by the fine image stabilization detector 3 may be the whole region of the single-frame imaging of the fundus imaging unit 9, or may also be a local region of the single-frame imaging of the fundus imaging unit 9, and may be specifically selected and set according to actual needs.
The precise image stabilization illuminating light source 4 can be a light source specially and independently arranged for precise image stabilization, or can also be an illuminating light source directly used by an eye fundus imaging instrument for eye fundus imaging, the position of the precise image stabilization illuminating light source can be independently arranged behind a rear light path 8 of the scanning image stabilization module as shown in figure 1, the precise image stabilization illuminating light source and the precise image stabilization detector 3 jointly use a special light path branch, and the precise image stabilization illuminating light source can also be arranged in a front light path 7 of the scanning image stabilization module or in the rear light path 8 of the scanning image stabilization module, so that the light path structure is further simplified, and the volume of the device is reduced.
The coarse image stabilization detector 2 and the fine image stabilization detector 3 are respectively connected with an image stabilization mirror deflection control module, the coarse image stabilization detector 2 and the fine image stabilization detector 3 respectively send coarse motion amount and fine motion amount into the image stabilization mirror deflection control module, the image stabilization mirror deflection control module calculates a deflection compensation instruction according to the coarse motion amount and the fine motion amount, controls the scanning image stabilization mirror 5 to deflect according to the deflection compensation instruction, adjusts the direction of fundus illumination light to adapt to and compensate eye movement, and enables the fundus imaging unit 9 to acquire a stable fundus image after eye movement compensation.
In this embodiment, the installation position of the scanning image stabilizing mirror 5 is different according to the optical path design of the fundus imaging instrument, and the scanning image stabilizing mirror itself may also be responsible for the fundus scanning imaging function, and it should be noted that, as long as the scanning image stabilizing mirror 5 adopts the coarse motion amount and the fine motion amount described in this embodiment to perform the eye movement compensation image stabilization, it is within the protection scope of this patent.
In this embodiment, the combination and splitting of the beacon light beam and the combination and splitting of the fundus illumination light beam can be implemented by using a plurality of beam splitters or equivalent optical elements, the positions of the beam splitters or the equivalent optical elements may be different due to the specific light path design of a fundus imaging instrument, fig. 1 only takes the case that the beam splitter 10, the beam splitter 11, the beam splitter 12 and the beam splitter 13 are all arranged behind the rear light path 8 of the scanning image stabilization module as an example, the beacon light emitted by the coarse image stabilization beacon light source 1 enters the rear light path 8 of the scanning image stabilization module through the beam splitter 10, the beam splitter 11 and the beam splitter 12, and the beacon light reflected by the fundus returns to the coarse image stabilization detector 2 through the original paths of the beam splitter 12, the beam splitter 11 and the beam splitter 10; fundus illumination light emitted by the fine image stabilization illumination light source 4 enters the scanning image stabilization module rear light path 8 through the beam splitter 13 and the beam splitter 12, and fundus illumination light reflected by the fundus region returns to the fine image stabilization detector 3 through the beam splitter 12 and the beam splitter 13. It should be noted that, for those skilled in the art, the number of the beam splitters and the positions of the beam splitters may be designed according to actual needs, and the number and the positions of the beam splitters which can meet the light transmission requirements of the coarse image stabilization beacon light source 1, the coarse image stabilization detector 2, the fine image stabilization detector 3, and the fine image stabilization lighting source 4 are all within the protection scope of the present patent.
The two-stage image stabilization device applied to eye movement compensation of the fundus imaging instrument provided by the embodiment adopts a coarse and fine two-stage image stabilization mode to perform eye movement compensation image stabilization, namely, the light spot image of beacon light is used for calculating the coarse movement amount of eye movement of a human eye, and a multi-frame fundus area image is used for calculating the fine movement amount of the eye movement of the human eye through an image digital processing method. The beacon light spot method is high in measurement speed, accuracy superior to that of a pixel level can be achieved through image motion amount calculation, and compared with the beacon light spot method that the motion amount measurement accuracy is inferior to that of the pixel level, the accuracy is higher, so that two-stage image stabilization is performed by combining the two methods, rapid and high-accuracy eye movement compensation image stabilization of an eye fundus imaging instrument can be achieved, a more stable image is obtained, and therefore the eye fundus imaging quality is improved.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.
Claims (5)
1. The utility model provides a be applied to doublestage image stabilization device of eye ground imaging instrument eye movement compensation which characterized in that: the device comprises a coarse image stabilization beacon light source (1), a coarse image stabilization detector (2), a fine image stabilization detector (3), a fine image stabilization lighting source (4), a scanning image stabilization mirror (5) and an image stabilization mirror deflection control module;
the double-stage image stabilizing device is arranged in an eye fundus imaging optical path and is used for performing eye movement compensation on the eye fundus imaging optical path, and the eye fundus imaging optical path comprises a human eye to be detected (6), a scanning image stabilizing module front optical path (7), a scanning image stabilizing module rear optical path (8) and an eye fundus imaging unit (9);
beacon light emitted by the coarse image stabilization beacon light source (1) enters the fundus of the eye (6) of the detected person after passing through the scanning image stabilization module rear light path (8), the scanning image stabilization mirror (5) and the scanning image stabilization module front light path (7), is focused into a light spot on the fundus, and returns to the coarse image stabilization detector (2) along the original path after passing through the beacon light reflected by the fundus, so that a light spot image is formed on the coarse image stabilization detector (2), and the coarse image stabilization detector (2) measures the displacement of the light spot image, so that the coarse movement amount of the eye movement of the human eye is obtained;
fundus illumination light emitted by the fine image stabilization illumination light source (4) enters the fundus of the human eye to be detected (6), fundus illumination light reflected by a fundus region enters the fine image stabilization detector (3) after passing through the scanning image stabilization module front light path (7), the scanning image stabilization mirror (5) and the scanning image stabilization module rear light path (8), the fine image stabilization detector (3) images the fundus region, a plurality of frames of fundus region images are collected, a plurality of frames of fundus region images are processed by an image digital processing method, and the fine movement amount of the eye movement of the human eye is obtained by calculation, wherein the image digital processing method is any one of an image matching processing method, a spectrum analysis processing method and a deep learning processing method;
and the image stabilizing mirror deflection control module calculates a deflection compensation instruction according to the coarse motion amount and the fine motion amount, controls the scanning image stabilizing mirror (5) to deflect according to the deflection compensation instruction, and adjusts the direction of fundus illumination light to enable the fundus imaging unit (9) to acquire a stable fundus image after eye movement compensation.
2. The dual-stage image stabilization device applied to ocular fundus imaging instrument eye movement compensation according to claim 1, wherein:
the precise image stabilization illuminating light source (4) adopts an illuminating light source used by an eyeground imaging instrument for eyeground imaging.
3. The dual-stage image stabilization device applied to ocular fundus imaging apparatus eye movement compensation according to claim 1 or 2, wherein:
and the fine image stabilizing illumination light source (4) is arranged behind the rear light path (8) of the scanning image stabilizing module.
4. The dual-stage image stabilization device applied to ocular fundus imaging apparatus eye movement compensation according to claim 1 or 2, wherein:
and the fine image stabilizing illumination light source (4) is arranged in the front light path (7) of the scanning image stabilizing module or the rear light path (8) of the scanning image stabilizing module.
5. The dual-stage image stabilization device applied to ocular fundus imaging apparatus eye movement compensation according to claim 1 or 2, wherein:
the fundus region image is the entire region or a partial region of single-frame imaging by the fundus imaging unit (9).
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| CN110301886B (en) * | 2019-06-28 | 2020-11-27 | 南京博视医疗科技有限公司 | Optical system for real-time closed-loop control of fundus camera and implementation method thereof |
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