CN112950536A - High attenuation region detection method and device and computer equipment - Google Patents

High attenuation region detection method and device and computer equipment Download PDF

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CN112950536A
CN112950536A CN202110098966.3A CN202110098966A CN112950536A CN 112950536 A CN112950536 A CN 112950536A CN 202110098966 A CN202110098966 A CN 202110098966A CN 112950536 A CN112950536 A CN 112950536A
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image
region
high attenuation
puncture
difference image
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CN112950536B (en
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胡扬
陈明
周海华
王汉禹
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Shanghai United Imaging Healthcare Co Ltd
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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
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    • G06COMPUTING; CALCULATING OR COUNTING
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    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10004Still image; Photographic image
    • G06T2207/10012Stereo images
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    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20212Image combination
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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
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    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30068Mammography; Breast
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30096Tumor; Lesion

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Abstract

The application relates to a high attenuation region detection method, a high attenuation region detection device and computer equipment. And when the stereotactic projection image and the puncture image are acquired, the positions of the needle holders are different. And obtaining a difference image according to the stereo positioning projection image and the puncture image. Setting a ratio threshold value, and determining a region larger than the ratio threshold value in the difference image as a first high attenuation region in the puncture image. By utilizing the characteristics that when the stereotactic projection image and the puncture image are obtained, the positions of the needle holders are different, and the attenuation of the puncture mechanism is much larger than that of human tissues, the detection of a high attenuation area in the puncture image is realized.

Description

High attenuation region detection method and device and computer equipment
Technical Field
The application relates to the technical field of medical instruments, in particular to a high attenuation region detection method and device and computer equipment.
Background
Diagnosis of breast disease, breast puncture is typically required in several cases: 1) the lump is found, the nature is not clear, and whether the lump is benign or malignant is clear through biopsy; 2) the breast cancer is highly suspected, before the treatment of the auxiliary chemotherapy, the breast cancer needs to be verified by biopsy and pathological examination, and the biological indexes of the breast cancer, namely estrogen receptor, progestational hormone receptor, HER-2 oncogene, Ki67 and the like, are examined to guide the selection of chemotherapeutic drugs; 3) when a doctor combines physical examination and auxiliary examination analysis and suspects that the breast tumor is suspicious breast cancer, the doctor recommends the patient to carry out puncture biopsy; 4) sometimes the breast tumor is not obvious when the patient is examined, but suspicious lesion is found under B ultrasonic or molybdenum target, and the doctor may also recommend needle biopsy.
Breast punctures are often performed under the guidance of imaging medicine (e.g., color ultrasound, X-ray, CT) to improve the accuracy of the puncture. All there is the metal object formation of image in the various types of image of puncture in-process collection, has the metal object in the image, can cause certain influence to the post processing effect of image, need get rid of these regions through the detection to the metal object. In the image before needle insertion and the image after needle insertion, objects with high attenuation such as a puncture mechanism can be imaged, so that the high attenuation objects exist in a large-area in the image, and the attenuation characteristics, the shapes and the position information of the imaged objects are various, so that certain difficulty is brought to detection.
Disclosure of Invention
Based on this, the application provides a high attenuation region detection method, device and computer equipment, which utilize the characteristics that when the stereotactic projection image and the puncture image are obtained, only the position of a needle holder is different, and the attenuation of a puncture mechanism is much larger than that of human tissues, so as to realize the detection of the high attenuation region in the puncture image.
A high attenuation region detection method comprising:
respectively acquiring a stereotactic projection image and a puncture image, wherein the needle holder is in different positions when the stereotactic projection image and the puncture image are acquired;
obtaining a difference image according to the stereotactic projection image and the puncture image;
setting a ratio threshold value, and determining a region larger than the ratio threshold value in the difference image as a first high attenuation region in the puncture image.
In one embodiment, the difference image is obtained by subtracting the puncture image from the stereotactic projection image; or the difference image is a relative difference image obtained by dividing the difference image and the stereo positioning projection image.
In one embodiment, the method further comprises the following steps:
obtaining an absolute difference image according to the difference image;
determining a region of the absolute difference image that is greater than the ratio threshold as an at least partially high attenuation union region, wherein the at least partially high attenuation union region is a union region of the stereotactic projection image and the puncture image;
determining at least one second high attenuation region in the stereotactic projection images;
merging a first region of the at least one second high attenuation region that does not occur in the high attenuation union region into the first high attenuation region.
In one embodiment, the method further comprises the following steps:
setting a region of the at least one second high attenuation region appearing in the high attenuation union region as a second region, and judging whether a corresponding gray value of the second region in the difference image is greater than zero;
and if the corresponding gray value of the second region in the difference image is greater than zero, merging the second region into the first high attenuation region.
In one embodiment, the method further comprises the following steps:
if the corresponding gray value of the second region in the difference image is less than or equal to zero, acquiring a first average gray value of a first high attenuation region in the puncture image;
judging whether a second average gray value of the second area in the puncture image is smaller than a preset multiple of the first average gray value;
and if the second average gray value is smaller than a preset multiple of the first average gray value, merging the second area into the first high attenuation area.
In one embodiment, the puncture images include pre-needle insertion images and post-needle insertion images.
A high attenuation region detection apparatus comprising:
the device comprises an acquisition unit, a display unit and a control unit, wherein the acquisition unit is used for acquiring a stereotactic projection image and a puncture image, and the positions of needle holders are different when the stereotactic projection image and the puncture image are acquired;
the first calculation unit is used for obtaining a difference image according to the stereotactic projection image and the puncture image; and
a determination unit configured to set a ratio threshold value and determine a region larger than the ratio threshold value in the difference image as a first high attenuation region in the puncture image.
In one embodiment, the method further comprises the following steps:
the second calculating unit is used for obtaining an absolute difference image according to the difference image; and
a determination unit for determining at least one second high attenuation region in the stereotactic projection images;
wherein the determination unit is further configured to determine a region larger than the ratio threshold in the absolute difference image as an at least partially high attenuation union region, wherein the at least partially high attenuation union region is a union region of the stereotactic projection image and the puncture image, and a first region of the at least one second high attenuation region that does not appear in the high attenuation union region is merged into the first high attenuation region.
In one embodiment, the determining unit is further configured to set, as the second region, a region that appears in the high attenuation union region in the at least one second high attenuation region, and determine whether a corresponding gray value of the second region in the difference image is greater than zero, and if the corresponding gray value of the second region in the difference image is greater than zero, merge the second region into the first high attenuation region.
A computer device comprising a memory storing a computer program and a processor implementing the steps of the high attenuation region detection method of any of the above embodiments when executing the computer program.
The high attenuation region detection method respectively acquires a stereotactic projection image and a puncture image. And when the stereotactic projection image and the puncture image are acquired, the positions of the needle holders are different. And obtaining a difference image according to the stereo positioning projection image and the puncture image. Setting a ratio threshold value, and determining a region larger than the ratio threshold value in the difference image as a first high attenuation region in the puncture image. By utilizing the characteristics that when the stereotactic projection image and the puncture image are obtained, the positions of the needle holders are different, and the attenuation of the puncture mechanism is much larger than that of human tissues, the detection of a high attenuation area in the puncture image is realized.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments or the conventional technologies of the present application, the drawings used in the descriptions of the embodiments or the conventional technologies will be briefly introduced below, it is obvious that the drawings in the following descriptions are only some embodiments of the present application, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic flow chart of a method for detecting a high attenuation region according to an embodiment of the present application;
FIG. 2 is a schematic perspective view of an embodiment of the present application;
FIG. 3 is a schematic view of a puncture image acquisition process and images provided in accordance with an embodiment of the present application;
FIG. 4 is a schematic diagram of various images acquired during a lancing process according to an embodiment of the present application;
FIG. 5 is a schematic diagram of obtaining a relative difference image according to an embodiment of the present application;
FIG. 6 is a schematic illustration of a first high attenuation region in an acquired penetration image provided by one embodiment of the present application;
FIG. 7 is a schematic diagram of obtaining a high attenuation union region according to an embodiment of the present application;
FIG. 8 is a schematic illustration of a second high attenuation region in a stereotactic projection image acquired in accordance with one embodiment of the present application;
FIG. 9 is a schematic diagram of a relationship between a second high attenuation region and a high attenuation union region in a stereotactic projection image obtained according to an embodiment of the present application;
FIG. 10 is a schematic structural diagram of a high attenuation region detection apparatus according to an embodiment of the present application;
fig. 11 is a schematic structural diagram of a high attenuation region detection apparatus according to another embodiment of the present application.
Description of the main element reference numerals
10. An acquisition unit; 20. a first calculation unit; 30. a determination unit; 40. a second calculation unit;
50. a determination unit.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present application more comprehensible, embodiments accompanying the present application are described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application. This application is capable of embodiments in many different forms than those described herein and those skilled in the art will be able to make similar modifications without departing from the spirit of the application and it is therefore not intended to be limited to the embodiments disclosed below.
It will be understood that, as used herein, the terms "first," "second," and the like may be used herein to describe various elements, but these elements are not limited by these terms. These terms are only used to distinguish one element from another. For example, a first acquisition module may be referred to as a second acquisition module, and similarly, a second acquisition module may be referred to as a first acquisition module, without departing from the scope of the present application. The first acquisition module and the second acquisition module are both acquisition modules, but are not the same acquisition module.
It will be understood that when an element is referred to as being "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein in the description of the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
For the needle biopsy under the guidance of X-ray, the general procedure is that the doctor or the operator controls the needle holder to hold the puncture needle to puncture the body cavity to obtain the biopsy tissue. In the process, a puncture image is shot at preset angles within a deflection angle range of-15 degrees to 15 degrees relative to the vertical direction. The puncture image is a projection image. The doctor or the operator can observe the position of the puncture needle by observing the puncture image, so as to guide the next puncture to be more accurate. Due to the fact that metal is highly attenuated under the multi-energy spectrum, artifacts appear around the puncture needle in the puncture image. The artifact will affect the accuracy of the position judgment of the puncture needle by a doctor or an operator, and thus the treatment effect of the metal puncture may be affected because the position judgment of the puncture needle is not accurate enough.
Referring to fig. 1, in order to overcome the effect of the puncture needle artifact in the puncture image, the present application provides a method for detecting a high attenuation region. The high attenuation region detection method comprises the following steps:
and S10, respectively acquiring a stereotactic projection image and a puncture image, wherein the positions of the needle holder are different when the stereotactic projection image and the puncture image are acquired.
And S20, obtaining a difference image according to the stereotactic projection image and the puncture image.
S30, a ratio threshold is set, and a region in the difference image larger than the ratio threshold is determined as a first high attenuation region in the puncture image.
Referring to fig. 2, the step of acquiring the stereotactic projection image may be to position the patient and immobilize the breast using a compression plate. After the positioning is finished, the positions of the compression plate and the breast are unchanged in the whole puncture process. Then, the bulb tube is set to have a deflection angle of 0 degree relative to the vertical direction, X rays are made to be incident perpendicular to the flat plate and obtain images, namely tracking images, and the lesion position is guaranteed to be in a pierceable range. And then, respectively taking one image by rotating the bulb tube clockwise and anticlockwise by 15 degrees relative to the vertical direction, wherein the images are named as a stereo image pair, and according to the projection position of the focus in the stereo image pair, the spatial position information of the focus in the breast can be calculated by combining system geometric parameters. And a doctor or an operator delineates the position of the lesion information according to the stereo image. One of the images in the stereo image pair is a stereotactic projection image.
In one optional embodiment, the puncture image includes a pre-needle insertion image and a post-needle insertion image. Referring to fig. 3, the step of acquiring the puncture image may be that a doctor or an operator controls the needle holder to move to the target point position, and installs a proper puncture needle. And (3) pressing a needle inserting switch, driving a needle holder to reach a lesion position by a puncture mechanism, and shooting images respectively at a deflection angle of-15 degrees relative to the vertical direction and a deflection angle of +15 degrees relative to the vertical direction before sampling, wherein the images are named as a pair of images before needle inserting so as to observe whether the needle inserting position is correct or not. After the needle inserting position is determined to be correct, performing puncture to obtain biopsy tissues; two images, namely an image pair after needle insertion, of which the deflection angle relative to the vertical direction is-15 degrees and an image pair after needle insertion is +15 degrees are photographed, and whether the biopsy tissue is taken out or not is confirmed. It will be appreciated that the above-described acquisition of stereotactic projection images and images of the puncture may be performed in a scenario in which only the position of the needle holder is different. Of course, if other effects are present (e.g., partial image interference), the stereotactic projection images and the puncture images may be acquired after eliminating these effects.
All images of various types collected in the puncture process can be imaged with metal objects. As shown in fig. 4, fig. 4(a), (b), and (c) are a tracking image (Scout image), a stereotactic projection image (Stereo Pair image), and a puncture image (prefix Pair image (pre-needle insertion image) or Postfire Pair image (post-needle insertion image)), respectively. Metal objects (such as black parts in fig. 4) exist in the image, which may have a certain effect on the post-processing effect of the image, and these regions need to be excluded by detecting the metal objects; in the Scout image and the Stereo Pair image, only one needle holder area enters the image, the position of the needle holder area in the image is relatively fixed, the gray information and the shape information are relatively fixed, and the metal area is easy to detect; in the Prefire Pair image and the Postfire Pair image, objects with high attenuation such as a puncture mechanism can be imaged, so that an implant exists in a large-area in the image, the attenuation characteristics, the shape and the position information of the imaged object are various, and certain difficulty is brought to detection. Therefore, the detection of the high attenuation area in the subsequent puncturing image at the same angle after the Stereo Pair image is acquired is carried out by virtue of the characteristics that the dose is unchanged, the swing position is unchanged, only the position of the needle holder is changed, and the attenuation of the puncturing mechanism is larger than that of human tissues in the process of acquiring the Stereo Pair image sequence, the Prefire Pair image sequence and the Postfire Pair image sequence; first, the Prefire Pair image and Postfire Pair image at the same angle are subtracted from the Stereo Pair image at the same angle, and the difference image is determined, thereby detecting a high attenuation region in the Prefire Pair image and Postfire Pair image.
In an alternative embodiment, the difference image is a difference image obtained by subtracting the puncture image from the stereotactic projection image, or the difference image is a relative difference image obtained by dividing the difference image by the stereotactic projection image.
The detection of high attenuation regions in the pre-needle insertion image is described as an example. Referring to fig. 5, a difference image is obtained by subtracting the puncture image (fig. 5(b)) from the stereotactic projection image (fig. 5(a)) with the same angle for setting the bulb, and then the difference image is divided by the stereotactic projection image to obtain a relative difference image (fig. 5 (c)); a ratio threshold is set, and if a region larger than the ratio threshold in the relative difference image is considered to be a region having a large difference from the stereotactic projection image in the pre-needle image, the region is directly determined to be a high attenuation region in the pre-needle image (as shown in fig. 6).
In this embodiment, the high attenuation region detection method obtains the stereotactic projection image and the puncture image respectively. And when the stereotactic projection image and the puncture image are acquired, the positions of the needle holders are different. And obtaining a difference image according to the stereo positioning projection image and the puncture image. Setting a ratio threshold value, and determining a region larger than the ratio threshold value in the difference image as a first high attenuation region in the puncture image. By utilizing the characteristics that when the stereotactic projection image and the puncture image are obtained, the positions of the needle holders are different, and the attenuation of the puncture mechanism is much larger than that of human tissues, the detection of a high attenuation area in the puncture image is realized.
In one embodiment, the high attenuation region detection method further includes:
and obtaining an absolute difference image according to the difference image. And judging the area which is larger than the ratio threshold value in the absolute difference image as an at least partial high attenuation union set area, wherein the at least partial high attenuation union set area is the union set area of the stereotactic projection image and the puncture image. At least one second high attenuation region in the stereotactic projection images is determined. Merging a first region of the at least one second high attenuation region that does not occur in the high attenuation union region into the first high attenuation region.
An absolute difference image is an image obtained by taking the absolute values of pixels at respective positions of the difference image. The description will be continued by taking the detection of a high attenuation region in the pre-needle insertion image as an example. The absolute value of the relative difference image is taken, and then thresholding operation is performed by using a ratio threshold value, so that the obtained white area shown in fig. 7 is the union of the high attenuation areas in the stereotactic projection image and the pre-needle-insertion image. The detection of high attenuation regions in the stereotactic image may be performed based on a gray-scale threshold method. And defining a high attenuation area in the stereo positioning image as a second high attenuation area. It is understood that the first high attenuation region and the second high attenuation region only have differences in the associated images. The number of second high attenuation regions may comprise a plurality of connected regions. As shown in fig. 8, two second high attenuation regions, i.e., high attenuation region 1 and high attenuation region 2, are included in the stereotactic projection image. And intersecting the second high attenuation region with the high attenuation union region, if the second high attenuation region does not intersect with the high attenuation union region, the second high attenuation region is also a high attenuation region in the pre-needle-insertion image, and the second high attenuation region and the high attenuation union region are merged into the first high attenuation region. The white region in fig. 9(a) is the high attenuation region 1, and fig. 9(a) does not intersect with fig. 7, and it is described that the white region in fig. 9(a) is also a high attenuation region in the pre-needle insertion image, and the white regions are merged into the first high attenuation region. Similarly, the white area in fig. 9(b) is the high attenuation area 2, and the intersection of fig. 9(b) and fig. 7 is the white area in fig. 9 (c). The complement of fig. 9(b) and 7 is a white area as in fig. 9 (d). Here, as the white area in fig. 9(d) does not intersect with fig. 7, it is described that the white area in fig. 9(d) is also a high attenuation area in the pre-needle insertion image, and is merged into the first high attenuation area.
In one embodiment, the high attenuation region detection method further includes:
and judging whether the corresponding gray value of a second region in the difference image, which is in the high attenuation union region, of the at least one second high attenuation region is greater than zero. And if the corresponding gray value of the second region in the difference image is greater than zero, merging the second region into the first high attenuation region.
The description will be continued by taking the detection of a high attenuation region in the pre-needle insertion image as an example. Taking intersection of each high attenuation region and the high attenuation union region in the stereo positioning image, if the intersection exists, the region may be a high attenuation region in the image before needle insertion, and at the moment, the high attenuation region in the image before needle insertion is overlapped with the high attenuation region in the stereo positioning image; as shown in fig. 9(c), the intersection region of the high attenuation region 2 in the pre-needle-insertion image and the high attenuation union region may be the needle holder region in the stereotactic projection image, but not the needle holder region in the pre-needle-insertion image; it is also possible that the needle holder area in the pre-needle insertion image is not the needle holder area in the stereotactic projection image. It is also possible to have both the needle holder area in the pre-needle insertion image and the needle holder area in the stereotactic projection image. If the value of the region in the difference image is positive, because the region is already determined as a high attenuation region in the stereotactic image and the gray level of the region is lower than that of the corresponding position in the pre-needle image, the region is also a high attenuation region in the pre-needle image and is merged into the first high attenuation region.
In one embodiment, the high attenuation region detection method further includes:
and if the corresponding gray value of the second region in the difference image is less than or equal to zero, acquiring a first average gray value of a first high attenuation region in the puncture image. And judging whether a second average gray value of the second area in the puncture image is smaller than a preset multiple of the first average gray value. And if the second average gray value is smaller than a preset multiple of the first average gray value, merging the second area into the first high attenuation area.
The description will be continued by taking the detection of a high attenuation region in the pre-needle insertion image as an example. If the gray value of the area in the difference image is less than or equal to zero, counting a first average gray value of the area which is judged to be high attenuation in the image before needle insertion, if a second average gray value of the area in the image before needle insertion is less than a certain multiple of the first average gray value of the area which is judged to be high attenuation, considering the area to be a high attenuation area, and combining the area to be the first high attenuation area.
In this embodiment, by using the characteristics that only the positions of the needle holders are different and the attenuation of the puncture mechanism is much greater than that of the human tissue when the stereotactic projection image and the puncture image are obtained, the detection of the high attenuation region in the puncture image is further realized.
Referring to fig. 10, the present application provides a high attenuation region detection apparatus. The high attenuation region detection apparatus includes an acquisition unit 10, a first calculation unit 20, and a determination unit 30.
The acquisition unit 10 is used for acquiring stereotactic projection images and puncture images. And when the stereotactic projection image and the puncture image are acquired, the positions of the needle holders are different. The first calculation unit 20 is configured to obtain a difference image according to the stereotactic projection image and the puncture image. The determination unit 30 is configured to set a ratio threshold, and determine a region larger than the ratio threshold in the difference image as a first high attenuation region in the puncture image.
The step of acquiring stereotactic projection images may be positioning the patient and immobilizing the breast with the compression plate. After the positioning is finished, the positions of the compression plate and the breast are unchanged in the whole puncture process. Then, the bulb tube is set to have a deflection angle of 0 degree relative to the vertical direction, X rays are made to be incident perpendicular to the flat plate and obtain images, namely tracking images, and the lesion position is guaranteed to be in a pierceable range. And then, respectively taking one image by rotating the bulb tube clockwise and anticlockwise by 15 degrees relative to the vertical direction, wherein the images are named as a stereo image pair, and according to the projection position of the focus in the stereo image pair, the spatial position information of the focus in the breast can be calculated by combining system geometric parameters. And a doctor or an operator delineates the position of the lesion information according to the stereo image. One of the images in the stereo image pair is a stereotactic projection image.
In one optional embodiment, the puncture image includes a pre-needle insertion image and a post-needle insertion image. The step of acquiring the puncture image may be that a doctor or an operator controls the needle holder to move to the target point position, and installs a proper puncture needle. Before sampling, one image is shot at a deflection angle of-15 degrees relative to the vertical direction and one image is shot at a deflection angle of +15 degrees relative to the vertical direction respectively, namely a pair of images before needle insertion, so as to observe whether the needle insertion position is correct. After the needle inserting position is determined to be correct, performing puncture to obtain biopsy tissues; two images, namely an image pair after needle insertion, of which the deflection angle relative to the vertical direction is-15 degrees and an image pair after needle insertion is +15 degrees are photographed, and whether the biopsy tissue is taken out or not is confirmed. It will be appreciated that the above-described acquisition of stereotactic projection images and images of the puncture may be performed in a scenario in which only the position of the needle holder is different. Of course, if other effects are present (e.g., partial image interference), the stereotactic projection images and the puncture images may be acquired after eliminating these effects.
In an alternative embodiment, the difference image is a difference image obtained by subtracting the puncture image from the stereotactic projection image, or the difference image is a relative difference image obtained by dividing the difference image by the stereotactic projection image.
The detection of high attenuation regions in the pre-needle insertion image is described as an example. Subtracting the puncture image from the stereotactic projection image with the same angle for setting the bulb tube to obtain a difference image, and then dividing the difference image and the stereotactic projection image to obtain a relative difference image; and setting a ratio threshold, wherein the area which is larger than the ratio threshold in the relative difference image is regarded as the area with larger difference from the stereotactic projection image in the pre-needle-insertion image, and directly judging the area as a high attenuation area in the pre-needle-insertion image.
In this embodiment, the high attenuation region detection apparatus obtains the stereotactic projection image and the puncture image separately. And when the stereotactic projection image and the puncture image are acquired, the positions of the needle holders are different. And obtaining a difference image according to the stereo positioning projection image and the puncture image. Setting a ratio threshold value, and determining a region larger than the ratio threshold value in the difference image as a first high attenuation region in the puncture image. By utilizing the characteristics that when the stereotactic projection image and the puncture image are obtained, the positions of the needle holders are different, and the attenuation of the puncture mechanism is much larger than that of human tissues, the detection of a high attenuation area in the puncture image is realized.
Referring to fig. 11, in one embodiment, the high attenuation region detection apparatus further includes a second calculation unit 40 and a determination unit 50.
The second calculating unit 40 is configured to obtain an absolute difference image according to the difference image. The determination unit 50 is adapted to determine at least one second high attenuation region in the stereotactic projection images. Wherein the determination unit 30 is further configured to determine a region of the absolute difference image larger than the ratio threshold as an at least partially high attenuation union region, wherein the at least partially high attenuation union region is a union region of the stereotactic projection image and the puncture image. The determination unit 30 merges first regions, which do not appear in the high attenuation union region, of the at least one second high attenuation region into the first high attenuation region.
The description will be continued by taking the detection of a high attenuation region in the pre-needle insertion image as an example. And taking an absolute value of the relative difference image, and performing thresholding operation by using a ratio threshold value to obtain a region B which is a union set of the high attenuation regions in the stereotactic projection image and the pre-needle-insertion image. The detection of high attenuation regions in the stereotactic image may be performed based on a gray-scale threshold method. And defining a high attenuation area in the stereo positioning image as a second high attenuation area. It is understood that the first high attenuation region and the second high attenuation region only have differences in the associated images. The number of second high attenuation regions may comprise a plurality of connected regions. And taking intersection of each high attenuation region and the high attenuation union set region in the stereotactic image, if the intersection does not exist, indicating that the region is also the high attenuation region in the image before needle insertion, and combining the high attenuation region and the high attenuation union set region into the first high attenuation region.
In one embodiment, the determining unit 30 is further configured to determine whether a corresponding gray value of a second region, which appears in the high attenuation union region, in the difference image is greater than zero, and merge the second region into the first high attenuation region if the corresponding gray value of the second region in the difference image is greater than zero.
If the corresponding gray value of the second region in the difference image is less than or equal to zero, the determining unit 30 is further configured to obtain a first average gray value of a first high attenuation region in the puncture image. And judging whether a second average gray value of the second area in the puncture image is smaller than a preset multiple of the first average gray value. And if the second average gray value is smaller than a preset multiple of the first average gray value, merging the second area into the first high attenuation area.
The description will be continued by taking the detection of a high attenuation region in the pre-needle insertion image as an example. Taking intersection of each high attenuation region and the high attenuation union region in the stereo positioning image, if the intersection exists, the region may be a high attenuation region in the image before needle insertion, and at the moment, the high attenuation region in the image before needle insertion is overlapped with the high attenuation region in the stereo positioning image; if the value of the region in the difference image is positive, because the region is already determined as a high attenuation region in the stereotactic image and the gray level of the region is lower than that of the corresponding position in the pre-needle image, the region is also a high attenuation region in the pre-needle image and is merged into the first high attenuation region. If the gray value of the area in the difference image is less than or equal to zero, counting a first average gray value of the area which is judged to be high attenuation in the image before needle insertion, if a second average gray value of the area in the image before needle insertion is less than a certain multiple of the first average gray value of the area which is judged to be high attenuation, considering the area to be a high attenuation area, and combining the area to be the first high attenuation area.
In this embodiment, by using the characteristics that only the positions of the needle holders are different and the attenuation of the puncture mechanism is much greater than that of the human tissue when the stereotactic projection image and the puncture image are obtained, the detection of the high attenuation region in the puncture image is further realized.
The present application provides a computer device. The computer device comprises a memory storing a computer program and a processor implementing the steps of the high attenuation region detection method according to any of the above embodiments when the processor executes the computer program.
The memory, which is a computer-readable storage medium, may be used for storing software programs, computer-executable programs, and modules, such as program instructions/modules corresponding to the magnetic resonance imaging method in the embodiments of the present application. The processor executes various functional applications of the device and data processing by executing software programs, instructions and modules stored in the memory, that is, implements the high attenuation region detection method described above.
The memory may mainly include a program storage area and a data storage area, wherein the program storage area may store an operating system, an application program required for at least one function. The storage data area may store data created according to the use of the terminal, and the like. Further, the memory may include high speed random access memory, and may also include non-volatile memory, such as at least one magnetic disk storage device, flash memory device, or other non-volatile solid state storage device. In some examples, the memory may further include memory located remotely from the processor, and these remote memories may be connected to the device over a network. Examples of such networks include, but are not limited to, the internet, intranets, local area networks, mobile communication networks, and combinations thereof.
In this embodiment, the computer device implements the high attenuation region detection method to obtain the stereotactic projection image and the puncture image respectively. And when the stereotactic projection image and the puncture image are acquired, only the position of the needle holder is different. And obtaining a difference image according to the stereo positioning projection image and the puncture image. Setting a ratio threshold value, and determining a region larger than the ratio threshold value in the difference image as a first high attenuation region in the puncture image. By utilizing the characteristics that when the stereotactic projection image and the puncture image are obtained, only the position of the needle holder is different, and the attenuation of the puncture mechanism is much larger than that of human tissues, the detection of a high attenuation area in the puncture image is realized.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the claims. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (10)

1. A method for detecting a high attenuation region, comprising:
respectively acquiring a stereotactic projection image and a puncture image, wherein the needle holder is in different positions when the stereotactic projection image and the puncture image are acquired;
obtaining a difference image according to the stereotactic projection image and the puncture image;
setting a ratio threshold value, and determining a region larger than the ratio threshold value in the difference image as a first high attenuation region in the puncture image.
2. The method for detecting a high attenuation region according to claim 1, wherein the difference image is obtained by subtracting the puncture image from the stereotactic projection image; or the difference image is a relative difference image obtained by dividing the difference image and the stereo positioning projection image.
3. The high attenuation region detection method according to claim 2, further comprising:
obtaining an absolute difference image according to the difference image;
determining a region of the absolute difference image that is greater than the ratio threshold as an at least partially high attenuation union region, wherein the at least partially high attenuation union region is a union region of the stereotactic projection image and the puncture image;
determining at least one second high attenuation region in the stereotactic projection images;
and merging the first areas which do not appear in the high attenuation union area in each second high attenuation area into the first high attenuation area.
4. The high attenuation region detection method according to claim 3, further comprising:
setting a region of the at least one second high attenuation region appearing in the high attenuation union region as a second region, and judging whether a corresponding gray value of the second region in the difference image is greater than zero;
and if the corresponding gray value of the second region in the difference image is greater than zero, merging the second region into the first high attenuation region.
5. The high attenuation region detection method according to claim 4, further comprising:
if the corresponding gray value of the second region in the difference image is less than or equal to zero, acquiring a first average gray value of a first high attenuation region in the puncture image;
judging whether a second average gray value of the second area in the puncture image is smaller than a preset multiple of the first average gray value;
and if the second average gray value is smaller than a preset multiple of the first average gray value, merging the second area into the first high attenuation area.
6. The method of claim 1, wherein the puncture images include pre-needle insertion images and post-needle insertion images.
7. A high attenuation region detection apparatus, comprising:
the device comprises an acquisition unit, a display unit and a control unit, wherein the acquisition unit is used for acquiring a stereotactic projection image and a puncture image, and the positions of needle holders are different when the stereotactic projection image and the puncture image are acquired;
the first calculation unit is used for obtaining a difference image according to the stereotactic projection image and the puncture image; and
a determination unit configured to set a ratio threshold value and determine a region larger than the ratio threshold value in the difference image as a first high attenuation region in the puncture image.
8. The high attenuation region detecting apparatus according to claim 7, further comprising:
the second calculating unit is used for obtaining an absolute difference image according to the difference image; and
a determination unit for determining at least one second high attenuation region in the stereotactic projection images;
wherein the determination unit is further configured to determine a region larger than the ratio threshold in the absolute difference image as an at least partially high attenuation union region, wherein the at least partially high attenuation union region is a union region of the stereotactic projection image and the puncture image, and a first region of the at least one second high attenuation region that does not appear in the high attenuation union region is merged into the first high attenuation region.
9. The apparatus according to claim 8, wherein the determining unit is further configured to set, as the second region, a region of the at least one second high attenuation region appearing in the high attenuation union region, and determine whether a corresponding gray-level value of the second region in the difference image is greater than zero, and if the corresponding gray-level value of the second region in the difference image is greater than zero, merge the second region into the first high attenuation region.
10. A computer device comprising a memory and a processor, the memory storing a computer program, characterized in that the processor, when executing the computer program, implements the steps of the high attenuation region detection method of any one of claims 1 to 6.
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