CN112932722A - Fixing device for subcutaneous injection of experimental rat - Google Patents

Fixing device for subcutaneous injection of experimental rat Download PDF

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Publication number
CN112932722A
CN112932722A CN202110112761.6A CN202110112761A CN112932722A CN 112932722 A CN112932722 A CN 112932722A CN 202110112761 A CN202110112761 A CN 202110112761A CN 112932722 A CN112932722 A CN 112932722A
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CN
China
Prior art keywords
fixing
mouse
cavity
fixing device
fixed
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Pending
Application number
CN202110112761.6A
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Chinese (zh)
Inventor
郑鸿
刘权兴
戴纪刚
周东
于莎莎
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Second Affiliated Hospital Army Medical University
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Second Affiliated Hospital Army Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Second Affiliated Hospital Army Medical University filed Critical Second Affiliated Hospital Army Medical University
Priority to CN202110112761.6A priority Critical patent/CN112932722A/en
Publication of CN112932722A publication Critical patent/CN112932722A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/006Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means

Abstract

The invention discloses a fixing device for subcutaneous injection of an experimental rat, which comprises a fixing seat, a fixing seat and a fixing device, wherein the fixing seat is internally provided with a cavity; the four-limb fixing mechanism comprises four fixing rubber bands, and the fixing rubber bands are arranged on the fixing seat and correspond to the four limbs of the mouse; and truck fixed establishment, including fixed cover, set up the through-hole of intercommunication cavity on the fixing base, the top of cavity is equipped with sliding connection and the baffle that can the switching through-hole, the one end and the fixing base surface of fixed cover are articulated mutually, and the other end can insert in the through-hole, be equipped with a plurality of elastic limiting plates of having along the axial on the medial surface of keeping away from the hinged end of fixed cover, the limiting plate sets up towards the hinged end direction. The use above-mentioned experimental mouse hypodermic injection fixing device, can enough fix the four limbs of mouse, can fix the truck of mouse again to can avoid the mouse to scratch the experimenter and the health struggle influence experiment effect when doing the subcutaneous injection experiment.

Description

Fixing device for subcutaneous injection of experimental rat
Technical Field
The invention particularly relates to a fixing device for subcutaneous injection of an experimental rat.
Background
The experimental mouse is a white fur rat or a mouse which is generally used as an experimental animal in teaching and research of subjects such as physiology, medicine, pharmacy and the like, different experimental purposes can be realized by carrying out subcutaneous injection on the mouse in medical research, and the experimental mouse has important medical value and scientific research significance.
Subcutaneous injection of mice is generally performed by pinching the skin of the mouse up, with the neck or outer thigh of the mouse selected. In the prior art, in order to ensure the safety of experimenters, a fixing device is usually adopted to fix the limbs of a mouse so as to prevent the experimenters from being scratched by the mouse. However, because subcutaneous injection needs to be uniform and slow, the effect of subcutaneous injection can be affected if the body of a mouse only fixed on four limbs struggles in the process of continuous injection.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides a fixing device for subcutaneous injection of an experimental mouse, which can fix the trunk of the mouse and ensure the smoothness of the subcutaneous injection.
In order to achieve the purpose, the invention is realized by the following technical scheme: a fixing device for subcutaneous injection of an experimental rat comprises a fixing seat with a cavity inside;
the four-limb fixing mechanism comprises four fixing rubber bands, and the fixing rubber bands are arranged on the fixing seat and correspond to the four limbs of the mouse; and
truck fixed establishment, including fixed cover, set up the through-hole of intercommunication cavity on the fixing base, the top of cavity is equipped with sliding connection and can the baffle of switching through-hole, the one end and the fixing base surface of fixed cover are articulated mutually, and the other end can insert in the through-hole, be equipped with a plurality of elastic limiting plates that have along circumference on the medial surface of the end of keeping away from of fixed cover, the limiting plate sets up towards articulated end direction.
Put the mouse on the fixing base, fix four limbs through four fixed rubber bands, rotate fixed cover and cover on the truck of mouse to insert fixed cover and push down in the through-hole, the baffle is transferred little with the aperture of through-hole during fixed, has elastic limiting plate and can pass the through-hole, and can not return, makes fixed cover can be fixed with the truck of mouse, and the aperture is transferred to reuse baffle after finishing using, and fixed cover of being convenient for takes out.
The subcutaneous injection fixing device for the experimental rat has the beneficial effects that: the four limbs of the mouse can be fixed, the laboratory worker is prevented from being scratched, the trunk of the mouse can be fixed, and the phenomenon that the injection effect is influenced by struggling of the body is avoided.
Further, four limbs fixed establishment still includes the pivot of setting in the cavity, the pivot sets up along the horizontal direction, the both ends of fixed rubber band all penetrate in the fixing base cavity to be connected with the pivot through the stay cord.
Before fixed four limbs, can loosen fixed rubber band slightly so that four limbs put into, rotate the pivot, drive the stay cord and twine in the pivot to will fix the rubber band and draw down and fix four limbs, thereby both facilitate the use and have better fixed effect again.
Further, four limbs fixed establishment still includes hollow stand, spring and release link, every all be equipped with the stand on the base of fixed rubber band department, logical groove has been seted up along vertical direction to the side of stand, the spring sets up in the stand, the release link sets up along the horizontal direction, and one end is connected with the spring in stretching into the stand from leading to the groove, and the other end is connected with the middle part of fixed rubber band.
When the fixed rubber band is pulled downwards, the reset rod is driven to move downwards, after the rotating shaft loosens the fixed rubber band, the spring drives the reset rod to move upwards, four limbs of the mouse are loosened, the fixed rubber band is erected when the mouse is not used, and the four limbs of the mouse are conveniently placed into the mouse.
Further, the top of cavity is equipped with the slide rail, baffle and slide rail sliding connection to be connected with the rack through the connecting rod, be equipped with the cover in the pivot and be equipped with the gear, the gear meshes with the rack mutually.
When the pivot pivoted, can drive the rack displacement through the gear to drive connecting rod and baffle and remove on the slide rail, the part is shielded with the through-hole to the baffle when the fixed rubber band of pulling, so that fixed cover inserts fixedly, uses the backplate of accomplishing to open the through-hole, and fixed rubber band also loosens simultaneously.
Furthermore, a plurality of strip-shaped grooves communicated with the cavity are formed in the fixing seat, two parallel strip-shaped grooves are formed in each fixing rubber band, sliding blocks are arranged in the strip-shaped grooves, and two ends of each fixing rubber band penetrate through the two sliding blocks and enter the cavity respectively;
the fixing base lateral wall is provided with a plurality of threaded holes communicated with the cavity, the threaded holes correspond to the fixed rubber band in position one to one, threaded connection screw rods are arranged in the threaded holes, and the screw rods are connected with two corresponding connected sliding blocks in a homogeneous mode.
Because the mice that do the experiment are not of the same size, can rotate the screw rod on the fixing base lateral wall, drive two sliders at the displacement of bar inslot to adjust the position of fixed rubber band, be convenient for fix the four limbs of the mice of different sizes.
Furthermore, the fixing seat is provided with a needle inlet hole on both sides of the head and the tail of the mouse.
The two needle inlet holes are respectively used for injecting the neck and the thigh of the mouse by inserting needles, so that the needle insertion is more convenient.
Further, still include the base, be equipped with two lead screw lifters that are close to both sides respectively on the base, lead screw lifter's sliding seat is fixed to be set up on the base, the spout of both ends respectively towards two needle inlet hole directions is seted up to the bottom of fixing base, lead screw top and spout sliding connection of lead screw lifter.
Because the sliding seat is fixed, the lead screw goes up and down to drive one of them one end of base and upwards rotates, and the lead screw slides in the spout and upwards jack-up the fixing base to the neck or the thigh portion injection of mouse when being convenient for experiment.
Furthermore, the spout is T type groove, the lead screw top of lead screw lift is equipped with the slide bar with spout sliding connection.
The sliding groove in the T-shaped groove can limit the sliding rod and avoid falling off.
Furthermore, rocking bars are arranged on sliding seats of the screw rod lifter, and fixing pins are sleeved on the two rocking bars.
The fixing pin is arranged on the two rocking rods, and one rocking rod can drive the other rocking rod to rotate together to enable the fixing seat to rise integrally.
Drawings
In order to more clearly illustrate the embodiments of the present invention, the drawings, which are required to be used in the embodiments, will be briefly described below. In all the drawings, the elements or parts are not necessarily drawn to actual scale.
Fig. 1 is a top view of a fixing device for subcutaneous injection of an experimental rat according to an embodiment of the present invention;
FIG. 2 is a front view of the hypodermic injection fixing device of the experimental rat shown in FIG. 1;
FIG. 3 is a front view of the hypodermic injection fixing device of the experimental rat shown in FIG. 1;
FIG. 4 is a side view of the hypodermic injection fixing device of the laboratory mouse shown in FIG. 1;
reference numerals:
10-a fixed seat, 11-a through hole, 12-a strip-shaped groove, 121-a sliding block, 13-a screw rod, 14-a push rod, 15-a needle inlet hole and 16-a sliding groove;
20-a four-limb fixing mechanism, 21-a fixing rubber band, 22-a rotating shaft, 221-a motor, 23-a pull rope, 24-an upright post, 241-a spring and 25-a reset rod;
30-a trunk fixing mechanism, 31-a fixing sleeve, 311-a limiting plate, 32-a baffle, 33-a connecting rod, 34-a rack and 35-a gear;
40-base, 41-screw rod lifter, 42-slide rod and 43-fixing pin.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.
Referring to fig. 1 to 4, the present invention provides a subcutaneous injection fixing device for an experimental mouse, which includes a fixing base 10, four limb fixing mechanisms 20 and a trunk fixing mechanism 30, wherein the mouse is placed on the fixing base 10, four limbs of the mouse are fixed by the four limb fixing mechanisms 20, and the trunk fixing mechanism 30 fixes the body, so that the experimental result can be prevented from being influenced by the mouse scratching experimental personnel or struggling the body during injection.
Specifically, as shown in fig. 1 and 2, the limb fixing mechanism 20 includes four fixing rubber bands 21 disposed on the fixing base 10, and the four fixing rubber bands correspond to the limbs of the mouse, respectively, for fixing the limbs of the mouse. The fixing seat 10 has a cavity inside, in this embodiment, a rotating shaft 22 is provided in the cavity along the horizontal direction, both ends of the fixing rubber band 21 penetrate into the cavity and are connected with the rotating shaft 22 through a pulling rope 23, a motor 221 is further provided in the cavity, and one end of the rotating shaft 22 is connected with an output shaft of the motor 221. In this embodiment, the four-limb fixing mechanism 20 further includes a hollow upright post 24, a spring 241 and a reset rod 25, each fixing rubber band 21 is provided with a vertical upright post 24, the spring 241 is arranged in the upright post 24, a through groove is axially formed in the side surface of the upright post 24, one end of the reset rod 25 extends into the upright post 24 from the through groove and is connected with the through groove in a sliding manner, and the other end of the reset rod is connected with the middle part of the fixing rubber band 21.
Before fixing, the mouse is placed on the fixed seat 10, at the moment, under the action of the spring 241, the reset rod 25 lifts the fixed rubber band 21, and four limbs of the mouse can be conveniently placed. The motor 221 drives the rotating shaft 22 to rotate, the pull rope 23 can be wound on the rotating shaft 22, so that the fixed rubber band 21 is pulled in the cavity, the four limbs of the mouse are fixed, and the fixed rubber band 21 drives the reset rod 25 to move downwards. After the mouse is used, the motor 221 rotates reversely, the pull rope 23 and the fixed rubber band 21 are loosened by the rotating shaft 22, and the spring 241 drives the reset rod 25 to move upwards, so that the mouse can be loosened.
In this embodiment, a plurality of strip-shaped grooves 12 communicating with the cavity are formed in the surface of the fixing seat 10, each fixing rubber band 21 is provided with the strip-shaped groove 12 arranged in parallel, a sliding block 121 and a push rod 14 are arranged in each strip-shaped groove 12, and two ends of each fixing rubber band 21 penetrate into the cavity from the sliding block 121 in each strip-shaped groove 12. The side wall of the fixing seat 10 is provided with a plurality of threaded holes, which are respectively in one-to-one correspondence with the positions of the plurality of fixed rubber bands 21. Threaded hole is equipped with threaded connection's screw rod 13, screw rod 13 penetrates in the cavity, push rod 14 sets up along the axial of bar groove 12 and one end is connected with screw rod 13, the other end has the disc and inlays to be established and rotate rather than in slider 121 and be connected, through rotating screw rod 13, can drive the push rod 14 and the slider 121 slip of two bar inslot 12, thereby adjust the position of fixed rubber band 21, according to laboratory mouse's volume size, adjust the position of fixed four limbs, can promote fixed effect, avoid the laboratory man of mouse scratch.
Specifically, as shown in fig. 1 and fig. 3, the trunk fixing mechanism 30 includes a fixing sleeve 31 that can be sleeved on the mouse body, the through hole 11 of the communicating cavity is provided on the surface of the fixing base 10, one end of the fixing sleeve 31 is hinged on the surface of the fixing base 10, the other end of the fixing sleeve 31 can be inserted into the through hole 11, a plurality of elastic limiting plates 311 are arranged on the inner side of the fixing sleeve along the axial direction, and the limiting plates 311 are arranged towards the direction of the hinged end. The bottom of the through hole 11 is provided with a baffle 32, and the baffle 32 can open and close the through hole 11 to adjust the pitch of the through hole 11.
Since the motor 221 and the rotating shaft 22 are provided in the present embodiment, the motor 221 can drive the trunk fixation mechanism 30 at the same time as the limb fixation mechanism 20. The top of the cavity is provided with a slide rail, the baffle 32 is arranged on the slide rail and is in sliding connection with the slide rail, the baffle 32 is connected with a rack 34 parallel to the slide rail through a connecting rod 33, a gear 35 is sleeved on the rotating shaft 22, and the gear 35 is meshed with the rack 34. The motor 221 is used for tensioning the fixed rubber band 21 through the rotating shaft 22 and the pull rope 23, the gear 35 rotates to drive the rack 34 to move, so that the baffle 32 is driven to slide on the sliding rail, the through hole 11 is reduced, the fixed sleeve 31 can be inserted into the through hole 11 at the moment, and the limiting plate 311 has elasticity and is in a barb shape, so that the limiting plate cannot be taken out after being inserted, and the fixing effect is achieved. After use, the motor 221 rotates reversely to move the baffle 32 reversely, so that the through hole 11 is enlarged, and the fixing strip can be taken out from the through hole 11.
Specifically, as shown in fig. 4, the two ends of the fixing base 10, which are opposite to the head and the tail of the mouse, are provided with needle inlet holes 15, so that experimenters can conveniently perform subcutaneous injection on the neck and the thigh of the mouse. The lower side of fixing base 10 is equipped with base 40, is connected with fixing base 10 through two lead screw lifters 41 on the base 40, and two lead screw lifters 41 are close to the both ends that are equipped with two and advance pinhole 15 respectively. The bottom of the fixed seat 10 is provided with a sliding chute 16 opened towards the two needle inlet holes 15, in this embodiment, the sliding chute 16 is a T-shaped groove, the sliding seat of the screw rod lifter 41 is arranged on the base 40 and is provided with a rocker, the top end of the screw rod is provided with a sliding rod 42 slidably connected with the sliding chute 16, and the sliding rod 42 can rotate in the sliding chute 16.
Since the sliding seat is fixed, by rotating one of the rocking bars, the screw rod can be driven to ascend to jack up one side of the fixed seat 10, and the sliding rod 42 slides and relatively rotates in the sliding groove 16. One end of the fixing seat 10 is lifted up, so that experimenters can conveniently perform subcutaneous injection on the neck or thigh of the mouse. Meanwhile, the fixing pins 43 can be sleeved on the two rockers, holes are formed in the two ends of each fixing pin 43 and are respectively sleeved on the two rockers, and the two lead screws can be driven to ascend together by shaking one of the rockers, so that the fixing base 10 is lifted upwards, and the convenience of operation of experimenters is improved.
The operating principle of the subcutaneous injection fixing device for the experimental rat is as follows: put on fixing base 10 with spreading out mouse four limbs, rotate screw 13 and adjust the position of slider 121 and fixed rubber band 21, then motor 221 drives pivot 22 and rotates, and stay cord 23 twines on pivot 22, will fix rubber band 21 and drop-down, and the four limbs of mouse are fixed. When the rotating shaft 22 rotates, the gear 35 drives the baffle 32 to displace through the rack 34 and the connecting rod 33, the pitch of the through hole 11 is reduced, the fixing sleeve 31 is inserted into the through hole 11 to fix the mouse body, and the limiting plate 311 can fix the fixing sleeve 31. One side or the whole of the fixed seat 10 is lifted by shaking the screw rod lifter 41, so that subcutaneous injection can be performed on the neck or the thigh of the mouse through the needle inserting hole 15.
Use above-mentioned experimental mouse hypodermic fixing device, can enough fix the four limbs of mouse, can fix the truck of mouse again, can avoid the mouse to scratch experimenter or health to struggle when doing the hypodermic and influence the injection effect to can also adjust the fixed position of four limbs and truck according to the size of mouse, have better fixed effect, can also promote hypodermic's convenience simultaneously.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention, and they should be construed as being included in the following claims and description.

Claims (9)

1. The utility model provides a fixing device is injected to experiment mouse subcutaneous which characterized in that: comprises a fixed seat with a cavity inside;
the four-limb fixing mechanism comprises four fixing rubber bands, and the fixing rubber bands are arranged on the fixing seat and correspond to the four limbs of the mouse; and
truck fixed establishment, including fixed cover, set up the through-hole of intercommunication cavity on the fixing base, the top of cavity is equipped with sliding connection and the baffle that can the switching through-hole, the one end and the fixing base surface of fixed cover are articulated mutually, and the other end can insert in the through-hole, be equipped with a plurality of elastic limiting plates of having along the axial on the medial surface of keeping away from the hinged end of fixed cover, the limiting plate sets up towards the hinged end direction.
2. The hypodermic fixing device for laboratory mice according to claim 1, wherein: the four limbs fixing mechanism is characterized by further comprising a rotating shaft arranged in the cavity, the rotating shaft is arranged along the horizontal direction, and the two ends of the fixed rubber band penetrate into the fixed seat cavity and are connected with the rotating shaft through pull ropes.
3. The hypodermic fixing device for laboratory mice according to claim 2, wherein: four limbs fixed establishment still includes hollow stand, spring and release link, every all be equipped with the stand on the base of fixed rubber band department, logical groove has been seted up along vertical direction to the side of stand, the spring sets up in the stand, the release link sets up along the horizontal direction, and one end is connected with the spring in stretching into the stand from leading to the groove, and the other end is connected with the middle part of fixed rubber band.
4. The hypodermic fixing device for laboratory mice according to claim 2, wherein: the top of cavity is equipped with the slide rail, baffle and slide rail sliding connection to be connected with the rack through the connecting rod, be equipped with the cover in the pivot and be equipped with the gear, the gear meshes with the rack mutually.
5. The hypodermic fixing device for laboratory mice according to claim 2, wherein: the fixing seat is provided with a plurality of strip-shaped grooves communicated with the cavity, two parallel strip-shaped grooves are formed in each fixing rubber band, sliding blocks are arranged in the strip-shaped grooves, and two ends of each fixing rubber band penetrate through the two sliding blocks respectively to enter the cavity;
the fixing base lateral wall is provided with a plurality of threaded holes communicated with the cavity, the threaded holes correspond to the fixed rubber band in position one to one, threaded connection screw rods are arranged in the threaded holes, and the screw rods are connected with two corresponding connected sliding blocks in a homogeneous mode.
6. The hypodermic fixing device for laboratory mice according to claim 1, wherein: the fixing seat is provided with a needle inlet hole at the two sides of the head and the tail of the mouse.
7. The hypodermic fixing device for laboratory mice according to claim 6, wherein: the base is provided with two lead screw lifters which are close to two sides respectively, sliding seats of the lead screw lifters are fixedly arranged on the base, sliding grooves with two ends facing two needle inlet hole directions are formed in the bottom of the fixing seat respectively, and the top ends of lead screws of the lead screw lifters are connected with the sliding grooves in a sliding mode.
8. The hypodermic fixing device for laboratory mice according to claim 7, wherein: the spout is T type groove, lead screw top of lead screw lift is equipped with the slide bar with spout sliding connection.
9. The hypodermic fixing device for laboratory mice according to claim 7, wherein: rocking bars are arranged on sliding seats of the screw rod lifter, and fixing pins are sleeved on the rocking bars.
CN202110112761.6A 2021-01-27 2021-01-27 Fixing device for subcutaneous injection of experimental rat Pending CN112932722A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110112761.6A CN112932722A (en) 2021-01-27 2021-01-27 Fixing device for subcutaneous injection of experimental rat

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Application Number Priority Date Filing Date Title
CN202110112761.6A CN112932722A (en) 2021-01-27 2021-01-27 Fixing device for subcutaneous injection of experimental rat

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CN112932722A true CN112932722A (en) 2021-06-11

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113475459A (en) * 2021-08-02 2021-10-08 西安工业大学 Lizard fixing device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203693823U (en) * 2014-01-07 2014-07-09 上海中医药大学附属岳阳中西医结合医院 Large and small mice fixing device
CN107753142A (en) * 2017-11-23 2018-03-06 张栩坤 A kind of animal and veterinary Baoding therapeutic system
CN211213648U (en) * 2019-06-27 2020-08-11 成都大学 Mouse fixing device for experiments
CN211409515U (en) * 2019-12-08 2020-09-04 遵义市第一人民医院 Mouse fixer and heating combined device
CN212308109U (en) * 2020-03-13 2021-01-08 侍昊 Fixing device for mouse acupuncture experiments

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203693823U (en) * 2014-01-07 2014-07-09 上海中医药大学附属岳阳中西医结合医院 Large and small mice fixing device
CN107753142A (en) * 2017-11-23 2018-03-06 张栩坤 A kind of animal and veterinary Baoding therapeutic system
CN211213648U (en) * 2019-06-27 2020-08-11 成都大学 Mouse fixing device for experiments
CN211409515U (en) * 2019-12-08 2020-09-04 遵义市第一人民医院 Mouse fixer and heating combined device
CN212308109U (en) * 2020-03-13 2021-01-08 侍昊 Fixing device for mouse acupuncture experiments

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113475459A (en) * 2021-08-02 2021-10-08 西安工业大学 Lizard fixing device

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