CN112927212B - OCT cardiovascular plaque automatic identification and analysis method based on deep learning - Google Patents

OCT cardiovascular plaque automatic identification and analysis method based on deep learning Download PDF

Info

Publication number
CN112927212B
CN112927212B CN202110263890.5A CN202110263890A CN112927212B CN 112927212 B CN112927212 B CN 112927212B CN 202110263890 A CN202110263890 A CN 202110263890A CN 112927212 B CN112927212 B CN 112927212B
Authority
CN
China
Prior art keywords
image
section
result
plaque
cross
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202110263890.5A
Other languages
Chinese (zh)
Other versions
CN112927212A (en
Inventor
张步春
马礼坤
孔祥勇
徐潇
侯杨
孙庆文
李昕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Yishi Network Technology Co ltd
Original Assignee
Shanghai Yishi Network Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Yishi Network Technology Co ltd filed Critical Shanghai Yishi Network Technology Co ltd
Priority to CN202110263890.5A priority Critical patent/CN112927212B/en
Publication of CN112927212A publication Critical patent/CN112927212A/en
Application granted granted Critical
Publication of CN112927212B publication Critical patent/CN112927212B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/04Architecture, e.g. interconnection topology
    • G06N3/045Combinations of networks
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/08Learning methods
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/10Segmentation; Edge detection
    • G06T7/136Segmentation; Edge detection involving thresholding
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • G06T2207/10101Optical tomography; Optical coherence tomography [OCT]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/20Special algorithmic details
    • G06T2207/20081Training; Learning
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30101Blood vessel; Artery; Vein; Vascular
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

The invention provides an OCT cardiovascular plaque automatic identification and analysis method based on deep learning, which comprises the following steps: deep section treatment: dividing the depth section of the OCT image to obtain a division result A1; cross section treatment: dividing the cross section of the OCT image to obtain a division result A2; and (3) sectional comprehensive treatment: integrating the deep section processing result A1 and the cross section processing result A2 and performing segmentation processing to obtain a segmentation result A; analysis of results: and calculating plaque attenuation index IPA according to the segmentation result A to obtain plaque category. The invention has reasonable design, integrates different image classification characteristics and OCT clinical characteristics, and can effectively solve the problem of weak plaque identification capability in the prior art by carrying out three-dimensional reconstruction and segmentation on the 3D OCT image and obtaining the quantization index IPA and finally classifying the plaque based on the IPA.

Description

OCT cardiovascular plaque automatic identification and analysis method based on deep learning
Technical Field
The invention relates to the field of image analysis, in particular to an OCT cardiovascular plaque automatic identification and analysis method based on deep learning.
Background
Cardiovascular diseases have developed as the first killer of resident disease death in China, causing immeasurable harm to national health and national economic development. Unstable lipid plaques are a major cause of the first-death cardiovascular disease, coronary heart disease.
Intravascular optical coherence tomography (IV-OCT) technology is rapidly developing into an effective means for diagnosing coronary heart disease due to its ultra-high imaging resolution (10-20 μm). IV-OCT images can clearly visualize different types of atherosclerotic plaques, known as "living tissue microscopy".
In segmenting plaques, N.Gessert et al pre-trains all models on ImageNet, then trains images using ResNet50-V2 and DenseNet121 models and polar and Cartesian coordinate systems to achieve segmentation and classification of several plaques for coronary OCT images, and attempts several different migration learning modes, finally comparing the serial results of several methods. Zhang et al propose a hybrid model of a faster-CNN network model with a fourth-order partial differential equation and a global local active contour model, first using the faster-CNN network model to detect calcified plaque areas, locating calcified plaque locations, setting a bounding box for a feature region, and setting the bounding box as an initial contour of the active contour model, and then minimizing the joint energy function of the fourth-order partial differential equation and the global local active contour model portion by a gradient descent and finite difference scheme, thereby segmenting calcified plaque in the coronary OCT image. He et al used OTSU automatic thresholding algorithm to segment tissue regions in the image, then input them as input sources into a CNN-based classifier, and divide focal tissue in the coronary OCT image into 5 different tissue categories, completing plaque characterization of the coronary OCT image. The problem of segmentation of coronary artery plaque is solved by using deep learning, a large data set is needed, or the data volume is increased through a large amount of data expansion, and the calculation amount and the requirement on hardware brought by a deep convolutional neural network are all difficulties of the deep learning in application to the segmentation of coronary artery OCT image plaque.
These methods are mainly classified into methods focusing on using deep learning, such as AlexNet, googleNet, VGG-Net, faster-CNN, denseNet, resNet, etc., in which plaque is segmented at each deep section, and then deep features are extracted from the segmented regions and then classified. These methods have achieved better results on image classification, such as ImageNet. They are mainly used for classifying and identifying different kinds of animals, plants, tools and other common articles of life. However, for OCT 3D images, the images produced by optical instrument interferometry, where plaque is typically small and 3D images, the ability to identify different plaques is typically weak, and there is a certain disadvantage.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide an OCT cardiovascular plaque automatic identification and analysis method based on deep learning, which is used for carrying out three-dimensional reconstruction and segmentation on a 3D OCT image to obtain a quantization index IPA and finally classifying the plaque based on the IPA.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
an OCT cardiovascular plaque automatic identification and analysis method based on deep learning comprises the following steps:
s100, deep section processing: dividing the depth section of the OCT image to obtain a division result A1;
s200, cross section processing: dividing the cross section of the OCT image to obtain a division result A2;
s300, section comprehensive treatment: integrating the deep section processing result A1 and the cross section processing result A2 and performing segmentation processing to obtain a segmentation result A;
s400, analyzing results: and calculating plaque attenuation index IPA according to the segmentation result A to obtain plaque category.
In a preferred embodiment of the present invention, in step S100, the deep section processing specific steps include:
s101, inputting a 2D Image { Image (i, j, k) of a depth section; k=1, 2,3, …, M } = { Image (i, j, 1), image (i, j, 2), image (i, j, 3), …, image (i, j, M) }, wherein Image (i, j, k) represents coordinates of each point in the 2D Image;
s102, outputting the segmented 2D image, wherein the size of the segmented 2D image is consistent with that of the input image, the pixels of the useful area are 1, the pixels of the useless area are 0, and after obtaining the 2D images of all the depth sections, the 3D image A1 is obtained through combination.
In a preferred embodiment of the present invention, the specific processing method in step S102 is as follows: and carrying out convolution operation on each 2D image of the depth section, and combining to obtain a 3D image A1.
In a preferred embodiment of the present invention, in step S200, the cross-section processing specific steps include:
s201, inputting a 2D Image { Image (i, j, k) of a cross section; i=1, 2,3, …, N } = { Image (1, j, k), image (2, j, k), image (3, j, k), …, image (N, j, k) }, wherein Image (i, j, k) represents coordinates of each point in the 2D Image;
s202, outputting the segmented 2D image, wherein the size of the segmented 2D image is consistent with that of the input image, the pixels of the useful area are 1, the pixels of the useless area are 0, and after the 2D images of all cross sections are obtained, the 3D image A2 is obtained through combination.
In a preferred embodiment of the invention, the respective 2D images of the cross-section are convolved to obtain the 3D image A2 in combination.
In a preferred embodiment of the present invention, in step S300, the cross-section integration processing includes the specific steps of:
s301, inputting all depth section segmentation results A1 and cross section segmentation results A2;
s302, comprehensive depth interface divisionThe segmentation result A1 and the cross-section segmentation result A2 calculate a segmentation result A, wherein
In a preferred embodiment of the present invention, in step S400, the specific steps of the result analysis include:
s401, calculating and inputting a segmentation result A according to a calculation formula of the segmentation result A;
s402, outputting plaque categories;
s403, calculating a value of plaque attenuation coefficient IPA:
where x is the plaque attenuation coefficient threshold, μ t For the attenuation coefficient, N (μ) t X) means the number of pixel points with attenuation coefficient larger than x, N total The effective area of the segmentation result a is shown.
Through the technical scheme, the invention has the following beneficial effects:
the invention has reasonable design, integrates different image classification characteristics and OCT clinical characteristics, and can effectively solve the problem of weak plaque identification capability in the prior art by carrying out three-dimensional reconstruction and segmentation on the 3D OCT image and obtaining the quantization index IPA and finally classifying the plaque based on the IPA.
Drawings
FIG. 1 is a flow chart of an OCT cardiovascular plaque automatic identification and analysis method based on deep learning;
FIG. 2 is a graph showing the calculation process of the segmentation result A1 of the OCT cardiovascular plaque automatic recognition and analysis method based on deep learning;
FIG. 3 is a graph showing the calculation process of the segmentation result A2 of the OCT cardiovascular plaque automatic recognition and analysis method based on deep learning;
FIG. 4 is a deep cross-sectional view of an OCT image of an OCT cardiovascular plaque automatic identification and analysis method based on deep learning according to the present invention;
fig. 5 is a cross-sectional view of an OCT image of a method for automatically identifying and analyzing cardiovascular plaques based on deep learning according to the present invention.
Detailed Description
The present invention will be described in further detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present invention more apparent.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the disclosure. As used in this disclosure and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
Referring to fig. 1, an embodiment of an OCT cardiovascular plaque automatic identification and analysis method based on deep learning according to the present invention is shown. In this embodiment, the plaque automatic identification and analysis method includes the following steps:
referring to fig. 1 and 2, step S100 is described in detail:
s100, deep section processing: and (3) performing segmentation processing on the depth section of the OCT image to obtain a segmentation result A1. The processing method of the segmentation result A1 comprises the following steps:
i. inputting a 2D Image { Image (i, j, k) of a depth section; k=1, 2,3, …, M } = { Image (i, j, 1), image (i, j, 2), image (i, j, 3), …, image (i, j, M) }, wherein Image (i, j, k) represents coordinates of each point in the 2D Image;
outputting the segmented 2D image, wherein the size of the segmented 2D image is consistent with that of the input image, the pixels of the useful area are 1, the pixels of the useless area are 0, and the 3D image A1 is obtained by combining the 2D images of all the depth sections. And performing convolution operation on each 2D image of the depth section, and combining to obtain a 3D image A1.
The specific treatment method is as follows:
Block1:
convolving a 2D Image (i, j, k) of a kth depth section, wherein k=1, 2,3, …, M, with a filter_k1 of 3*3 to obtain a result_k1, convolving a filter_k2 of 3*5 to obtain a result_k2, convolving a filter_k3 of 5*3 to obtain a result_k3, convolving a filter_k4 of 5*5 to obtain a result_k4, a1×result_k1+a2×result_k2+a3×result_k3+a4×result_k4=result_k1.
Block_k_2, block_k_3, block_k_4: the structure is the same as block_k_1.
Result k B1 passes through blockk2=result k B2,
result k B2 passes through blockk3=result k B3,
result k B3 passes through blockk4=result k B4,
c1*Result_k_B1+c2*Result_k_B2+c3*Result_k_B3+c4*Result_k_B4=A1。
referring to fig. 1 and 3, step S200 is described in detail:
s200, cross section processing: and performing segmentation processing on the cross section of the OCT image to obtain a segmentation result A2. The processing method of the segmentation result A2 comprises the following steps:
i. inputting a 2D Image { Image (i, j, k) of the cross section; i=1, 2,3, …, N } = { Image (1, j, k), image (2, j, k), image (3, j, k), …, image (N, j, k) }, wherein Image (i, j, k) represents coordinates of each point in the 2D Image;
outputting the segmented 2D image, wherein the size of the segmented 2D image is consistent with that of the input image, the pixels of the useful area are 1, the pixels of the useless area are 0, and after the 2D images of all cross sections are obtained, the 3D image A2 is obtained through combination. Wherein, convolution operation is carried out on each 2D image of the cross section, and the 3D images A2 are obtained in a combined way.
The specific method is as follows:
Block1:
convolving the i-th cross-section 2D Image { Image (i, j, k), i=1, 2,3, …, N }, performing a convolution operation on the filter_i1 of 3*3 to obtain result_i1, performing a convolution operation on the filter_i2 of 3*5 to obtain result_i2, performing a convolution operation on the filter_i3 of 5*3 to obtain result_i3, performing a convolution operation on the filter_i4 of 5*5 to obtain result_i4, b1×result_i1+b2×result_i2+b3×result_i3+b4×result_i4=result_i_b1.
Block2, block3, block4: the structure is the same as Block 1.
Result i B1 passes through block2=result i B2,
result i B2 passes through block3=result i B3,
result i B3 passes through block4=result i B4,
d1*Result_i_B1+d2*Result_i_B2+d3*Result_i_B3+d4*Result_i_B4=A2。
referring to fig. 1, step S300 is described in detail:
s300, section comprehensive treatment: and integrating the depth section processing result A1 and the cross section processing result A2, and performing segmentation processing to obtain a segmentation result A. The processing method of the segmentation result A comprises the following steps:
i. inputting all the depth section segmentation results A1 and the cross section segmentation results A2;
ii, integrating the depth interface segmentation result A1 and the cross section segmentation result A2 to calculate a segmentation result A, wherein
The specific algorithm is as follows:
A=zeros(width=A1.width,height=A1.height,length=A1.length)
forifrom0toA1.width
forjfrom0toA1.height
forkfrom0toA1.length
ifA1(i,j,k)belongstoA2:
A(i,j,k)=A1(i,j,k)。
referring to fig. 1, step S400 is described in detail:
s400, analyzing results: and calculating plaque attenuation index IPA according to the segmentation result A to obtain plaque category. The specific method for analyzing the result is as follows:
i. calculating and inputting a segmentation result A according to a calculation formula of the segmentation result A;
outputting plaque categories;
calculating the value of plaque attenuation coefficient IPA:
where x is the plaque attenuation coefficient threshold, μ t For the attenuation coefficient, N (μ) t X) means the number of pixel points with attenuation coefficient larger than x, N total The effective area of the segmentation result a is shown. IPA represents plaque attenuation index (index) to quantify the degree of plaque attenuation in blood vessels. The calculation method is that when the pixel fraction of different types of plaques in the attenuation map is larger than the attenuation coefficient threshold value x, the pixel fraction is multiplied by 1000. The present study represents fibrous plaque with calculated value IPA6, IPA11 indicating lipid plaque. Among them, the larger the IPA, the worse the plaque stability.
The invention considers the characteristics of common image classification, combines the clinical characteristics of OCT, and simultaneously analyzes two sections of OCT images: deep section and cross section. Fig. 4 and 5 are 2D images of the depth cross section and the cross section of OCT, respectively. On the depth section: each 2D cross-section of the OCT image presents a circular or quasi-circular interference aperture; on the cross section, the OCT image can be viewed from the cross section after three-dimensional reconstruction, and each cross section is a 2D image and is specifically characterized in that a certain area in the middle is provided with a transverse bent interval stripe. The problem of weak plaque identification capability in the prior art can be effectively solved by performing three-dimensional reconstruction and segmentation on the 3D OCT image and obtaining a quantization index IPA and finally classifying the plaque based on the IPA.
While the invention has been described with respect to preferred embodiments thereof, it will be understood by those skilled in the art that various modifications and additions may be made without departing from the scope of the invention. Equivalent embodiments of the present invention will be apparent to those skilled in the art having the benefit of the teachings disclosed herein, when considered in the light of the foregoing disclosure, and without departing from the spirit and scope of the invention; meanwhile, any equivalent changes, modifications and evolution of the above embodiments according to the essential technology of the present invention still fall within the scope of the technical solution of the present invention.

Claims (5)

1. The OCT cardiovascular plaque automatic identification and analysis method based on deep learning is characterized by comprising the following steps of:
s100, deep section processing: dividing the depth section of the OCT image, and carrying out four convolution operations on the 2D image of the depth section to obtain a division result A1;
s200, cross section processing: dividing the cross section of the OCT image, and performing convolution operation on the 2D image of the cross section for four times to obtain a division result A2;
s300, section comprehensive treatment: integrating the deep section processing result A1 and the cross section processing result A2 and performing segmentation processing to obtain a segmentation result A;
in step S300, the section integrated processing specifically includes:
s301, inputting all depth section segmentation results A1 and cross section segmentation results A2;
s302, calculating a segmentation result A by integrating the depth interface segmentation result A1 and the cross section segmentation result A2, wherein
S400, analyzing results: calculating plaque attenuation index IPA according to the segmentation result A to obtain plaque category;
in step S400, the specific steps of the result analysis include:
s401, calculating and inputting a segmentation result A according to a calculation formula of the segmentation result A;
s402, outputting plaque categories;
s403, calculating a value of plaque attenuation coefficient IPA:
where x is the plaque attenuation coefficient threshold, μ t For the attenuation coefficient, N (μ) t X) means the number of pixel points with attenuation coefficient larger than x, N total The effective area of the segmentation result a is shown.
2. The method for automatically identifying and analyzing cardiovascular plaques based on deep learning OCT according to claim 1, wherein in step S100, the deep cross-section processing comprises the specific steps of:
s101, inputting a 2D Image { Image (i, j, k) of a depth section; k=1, 2,3, …, M } = { Image (i, j, 1), image (i, j, 2), image (i, j, 3), …, image (i, j, M) }, wherein Image (i, j, k) represents coordinates of each point in the 2D Image;
s102, outputting the segmented 2D image, wherein the size of the segmented 2D image is consistent with that of the input image, the pixels of the useful area are 1, the pixels of the useless area are 0, and after obtaining the 2D images of all the depth sections, the 3D image A1 is obtained through combination.
3. The method for automatically identifying and analyzing OCT cardiovascular plaque based on deep learning according to claim 2, wherein the specific processing method in step S102 is as follows: and carrying out convolution operation on each 2D image of the depth section, and combining to obtain a 3D image A1.
4. The method for automatic recognition and analysis of deep learning based OCT cardiovascular plaque of claim 1, wherein in step S200, the cross-section processing comprises the specific steps of:
s201, inputting a 2D Image { Image (i, j, k) of a cross section; i=1, 2,3, …, N } = { Image (1, j, k), image (2, j, k), image (3, j, k), …, image (N, j, k) }, wherein Image (i, j, k) represents coordinates of each point in the 2D Image;
s202, outputting the segmented 2D image, wherein the size of the segmented 2D image is consistent with that of the input image, the pixels of the useful area are 1, the pixels of the useless area are 0, and after the 2D images of all cross sections are obtained, the 3D image A2 is obtained through combination.
5. The automatic recognition and analysis method of cardiovascular plaques based on deep learning of claim 1, wherein the respective 2D images of the cross-sections are convolved to obtain a 3D image A2 in combination.
CN202110263890.5A 2021-03-11 2021-03-11 OCT cardiovascular plaque automatic identification and analysis method based on deep learning Active CN112927212B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110263890.5A CN112927212B (en) 2021-03-11 2021-03-11 OCT cardiovascular plaque automatic identification and analysis method based on deep learning

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110263890.5A CN112927212B (en) 2021-03-11 2021-03-11 OCT cardiovascular plaque automatic identification and analysis method based on deep learning

Publications (2)

Publication Number Publication Date
CN112927212A CN112927212A (en) 2021-06-08
CN112927212B true CN112927212B (en) 2023-10-27

Family

ID=76172610

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110263890.5A Active CN112927212B (en) 2021-03-11 2021-03-11 OCT cardiovascular plaque automatic identification and analysis method based on deep learning

Country Status (1)

Country Link
CN (1) CN112927212B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113538471B (en) * 2021-06-30 2023-09-22 上海联影医疗科技股份有限公司 Plaque segmentation method, plaque segmentation device, computer equipment and storage medium
CN114469337A (en) * 2021-07-05 2022-05-13 深圳市中科微光医疗器械技术有限公司 Ablation catheter assembly, laser ablation system and method
CN113538365A (en) * 2021-07-13 2021-10-22 深圳市中科微光医疗器械技术有限公司 Method and device for calculating IPA of intra-cavity OCT image

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011260A (en) * 2006-02-01 2007-08-08 西门子公司 Method and CT system for detecting and differentiating plaque in vessel structures of a patient
CN104398271A (en) * 2014-11-14 2015-03-11 西安交通大学 Method using three-dimensional mechanics and tissue specific imaging of blood vessels and plaques for detection
CN104794708A (en) * 2015-04-10 2015-07-22 浙江工业大学 Atherosclerosis plaque composition dividing method based on multi-feature learning
CN109697459A (en) * 2018-12-04 2019-04-30 云南大学 One kind is towards optical coherence tomography image patch Morphology observation method
CN110136157A (en) * 2019-04-09 2019-08-16 华中科技大学 A kind of three-dimensional carotid ultrasound image vascular wall dividing method based on deep learning
CN110223781A (en) * 2019-06-03 2019-09-10 中国医科大学附属第一医院 A kind of various dimensions plaque rupture Warning System
CN111161216A (en) * 2019-12-09 2020-05-15 杭州脉流科技有限公司 Intravascular ultrasound image processing method, device, equipment and storage medium based on deep learning
CN111445473A (en) * 2020-03-31 2020-07-24 复旦大学 Vascular membrane accurate segmentation method and system based on intravascular ultrasound image sequence multi-angle reconstruction
CN111768403A (en) * 2020-07-09 2020-10-13 成都全景恒升科技有限公司 Calcified plaque detection decision-making system and device based on artificial intelligence algorithm

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3363350B1 (en) * 2009-09-23 2019-12-11 Lightlab Imaging, Inc. Lumen morphology and vascular resistance measurements data collection systems, apparatus and methods
US9693755B2 (en) * 2012-01-19 2017-07-04 Konica Minolta, Inc. Ultrasound diagnostic device and method for controlling ultrasound diagnostic device
US20140303499A1 (en) * 2013-04-09 2014-10-09 Konica Minolta, Inc. Ultrasound diagnostic apparatus and method for controlling the same
US11432719B2 (en) * 2019-03-14 2022-09-06 Oregon Health & Science University Visual field simulation using optical coherence tomography and optical coherence tomographic angiography

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101011260A (en) * 2006-02-01 2007-08-08 西门子公司 Method and CT system for detecting and differentiating plaque in vessel structures of a patient
CN104398271A (en) * 2014-11-14 2015-03-11 西安交通大学 Method using three-dimensional mechanics and tissue specific imaging of blood vessels and plaques for detection
CN104794708A (en) * 2015-04-10 2015-07-22 浙江工业大学 Atherosclerosis plaque composition dividing method based on multi-feature learning
CN109697459A (en) * 2018-12-04 2019-04-30 云南大学 One kind is towards optical coherence tomography image patch Morphology observation method
CN110136157A (en) * 2019-04-09 2019-08-16 华中科技大学 A kind of three-dimensional carotid ultrasound image vascular wall dividing method based on deep learning
CN110223781A (en) * 2019-06-03 2019-09-10 中国医科大学附属第一医院 A kind of various dimensions plaque rupture Warning System
CN111161216A (en) * 2019-12-09 2020-05-15 杭州脉流科技有限公司 Intravascular ultrasound image processing method, device, equipment and storage medium based on deep learning
CN111445473A (en) * 2020-03-31 2020-07-24 复旦大学 Vascular membrane accurate segmentation method and system based on intravascular ultrasound image sequence multi-angle reconstruction
CN111768403A (en) * 2020-07-09 2020-10-13 成都全景恒升科技有限公司 Calcified plaque detection decision-making system and device based on artificial intelligence algorithm

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Molecular pathobiology of scleritis and its therapeutic implications;Undurti N Das;;International Journal of Ophthalmology(第01期);全文 *
OCT纵向图像形成分析;曾绍群,骆清铭,刘贤德,徐海峰,李再光;电子学报(第10期);全文 *
Optical coherence tomography angiography of the peripapillary region and macula in normal, primary open angle glaucoma, pseudoexfoliation glaucoma and ocular hypertension eyes;Helin Ceren Kse;Oya Tekeli;;International Journal of Ophthalmology(第05期);全文 *
光学相干层析成像技术原理及研究进展;陆冬筱;房文汇;李玉瑶;李金华;王笑军;;中国光学(第05期);全文 *
基于深度学习的颈动脉超声图像斑块分割算法;蔡梦媛;周然;程新耀;丁明跃;;生命科学仪器(第03期);全文 *

Also Published As

Publication number Publication date
CN112927212A (en) 2021-06-08

Similar Documents

Publication Publication Date Title
CN112927212B (en) OCT cardiovascular plaque automatic identification and analysis method based on deep learning
CN109166124B (en) Retinal blood vessel morphology quantification method based on connected region
CN108961261B (en) Optic disk region OCT image hierarchy segmentation method based on space continuity constraint
EP2285266B1 (en) Automatic cup-to-disc ratio measurement system
US7992999B2 (en) Automated assessment of optic nerve head with spectral domain optical coherence tomography
US8111896B2 (en) Method and system for automatic recognition of preneoplastic anomalies in anatomic structures based on an improved region-growing segmentation, and commputer program therefor
TWI544898B (en) Device and method for determining a skin inflammation score
CN113420826B (en) Liver focus image processing system and image processing method
JP2005199040A (en) Method and apparatus for processing image data to aid in detecting disease
Chen et al. Automated ventricular systems segmentation in brain CT images by combining low-level segmentation and high-level template matching
CN113610808B (en) Group brain map individuation method, system and equipment based on individual brain connection diagram
US20150371400A1 (en) Segmentation and identification of closed-contour features in images using graph theory and quasi-polar transform
CN107895364B (en) A kind of three-dimensional reconstruction system for the preoperative planning of virtual operation
JP2009531117A (en) Method and system for automatically recognizing precancerous abnormalities in anatomical structures and corresponding computer program
CN111415324B (en) Classification and identification method for brain disease focus image space distribution characteristics based on magnetic resonance imaging
US20070049839A1 (en) System and method for automated airway evaluation for multi-slice computed tomography (msct) image data using airway lumen diameter, airway wall thickness and broncho-arterial ratio
CN108416793B (en) Choroidal vessel segmentation method and system based on three-dimensional coherence tomography image
Dodo et al. Graph-Cut Segmentation of Retinal Layers from OCT Images.
Bodzioch et al. New approach to gallbladder ultrasonic images analysis and lesions recognition
Xu et al. Weakly supervised detection of central serous chorioretinopathy based on local binary patterns and discrete wavelet transform
CN112638262A (en) Similarity determination device, method, and program
CN116725563B (en) Eyeball salience measuring device
KR101514795B1 (en) Quantification method of vessel
Niessen et al. Error metrics for quantitative evaluation of medical image segmentation
CN115969400A (en) Apparatus for measuring area of eyeball protrusion

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant